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diff --git a/.gitattributes b/.gitattributes new file mode 100644 index 0000000..6833f05 --- /dev/null +++ b/.gitattributes @@ -0,0 +1,3 @@ +* text=auto +*.txt text +*.md text diff --git a/36496-0.txt b/36496-0.txt new file mode 100644 index 0000000..0b71015 --- /dev/null +++ b/36496-0.txt @@ -0,0 +1,8825 @@ +The Project Gutenberg EBook of On the cattle plague: or, Contagious typhus +in horned cattle. Its history, origin, desc, by Honoré Bourguignon + +This eBook is for the use of anyone anywhere at no cost and with +almost no restrictions whatsoever. You may copy it, give it away or +re-use it under the terms of the Project Gutenberg License included +with this eBook or online at www.gutenberg.org + + +Title: On the cattle plague: or, Contagious typhus in horned cattle. Its history, origin, description, and treatment + +Author: Honoré Bourguignon + +Release Date: June 22, 2011 [EBook #36496] + +Language: English + +Character set encoding: UTF-8 + +*** START OF THIS PROJECT GUTENBERG EBOOK ON THE CATTLE PLAGUE *** + + + + +Produced by Barbara Kosker, Bryan Ness and the Online +Distributed Proofreading Team at https://www.pgdp.net + + + + + + + +-----------------------------------------------+ + | Transcriber's Note: | + | | + | Inconsistent hyphenation and spelling in the | + | original document have been preserved. | + | | + | Greek words are transliterated and marked | + | +like so+. | + | | + +-----------------------------------------------+ + + + + + ON THE + CATTLE PLAGUE: + OR, + Contagious Typhus in Horned Cattle. + + ITS HISTORY, ORIGIN, DESCRIPTION, AND TREATMENT. + + + + + BY + H. BOURGUIGNON, + + Doctor of the Faculté de Paris, Fellow of the Société de Médecine + de Paris; Laureate of the Institute of France, Member of the + Legion of Honour, etc. + + + + + "Scribo nec ficta, nee picta, sed quæ ratio, + sensus et experientia docent." + + + + + PHILADELPHIA: + J. B. LIPPINCOTT & CO. + LONDON: J CHURCHILL & SONS. + 1869. + + + + + TO + MISS BURDETT COUTTS. + + + MADAM, + +The numerous services which you have rendered, and the interest you have +shown in the calamitous epizootic which at this moment decimates the +noble herds of England, have prompted me to dedicate the following pages +to you, satisfied that I am only giving public expression to the homage +felt for you by many of your fellow-countrymen. + +I have the honour to be, Madam, + + With respect, your obedient servant, + + H. BOURGUIGNON. + + + + +PREFACE. + + +Nations, during the successive phases of their evolution on the globe, +in which they advance from a state of infancy and barbarism to one of +virility and civilization, from civilization to decadence or senility; +and from decadence to their final extinction, are liable to numberless +calamities. + +These calamities are produced by moral causes, and are then called +social Revolutions; and in other instances from physical causes, and +then they are termed Cataclysms, Epidemics, or Epizootics. + +In these crises, the initiative and devotion of individuals, the public +administration, and the application of knowledge acquired in the Arts +and Sciences, afford collectively an infallible criterion for +ascertaining the position which a nation occupies in the scale of +civilization, and the value of its religious, social, and political +institutions. + +Calamities always leave behind them disasters and victims, but they +bequeath also a precious legacy. Nations which are called upon for fresh +and progressive efforts, find in the experience they have gained a new +source of strength and means of future greatness. I am convinced that +this will be the case with England; though, helpless for the moment, and +unable to stay the Cattle Plague which now ravages her entire extent, +she will in future be found better prepared to resist the inroads of +such a direful enemy. + +No branch of human knowledge has been more rudely tested during the +present epizootic than medical science. Many persons have been astounded +at its helplessness; but if they had reflected at what a distance +medicine has to follow in the wake of the exact sciences by which it is +furnished with instruments for prosecuting its researches,--that +organic chemistry progresses but slowly,--that the Cattle Plague was +entirely unknown to the present generation of medical men in +England,--and that the means for its scientific and practical study have +been therefore wholly wanting, they would have been less surprised to +find that it is as difficult to cure the Cattle Plague as it, is to cure +phthisis, cancer, hydrophobia, and the cholera, against which medicine +but too often is of little avail. + +In times of great national calamity it behoves every one to contribute +in proportion to his talents, fortune, or abilities, to alleviate the +effects of the common misfortune. The poor man's mite, and the honest +intention of the most insignificant, when added to the budget of common +efforts, have their relative value; and it is for these reasons that I +have published the following monograph on the Cattle Plague. + +If it assists in any way to the extinction of the present epizootic, or +if it serve to point out the necessity of combining the study of +comparative pathology with that of medicine, I shall feel that I have +contributed something which may favour my claim to be enrolled among the +citizens of England. + +This book, as may easily be seen, was originally written in my native +language. A few kind and obliging friends--more particularly Mr. Taylor +Sinnett, Drs. Clapton and Gervis, of St. Thomas's Hospital, and Mr. +Berridge, of the British Museum--have rendered me the greatest +assistance in the translation. Without the guidance of such competent +auxiliaries I could not have performed my arduous task. + +I therefore beg to return to those gentlemen, and to all those who have +assisted me on this occasion, my sincerest and most grateful thanks. + + H. B. + + + + +CONTENTS. + + + PAGE + + Introduction 1 + + + FIRST PART. + + The History of the Contagious Typhus of the Ox, from + the remotest Times down to the Present Day 5 + + + SECOND PART. + + CHAPTER I.--On Typhus Disease in general, and the + Typhus which affects the Ox in particular 72 + + CHAPTER II.--The Origin and Causes of the Ox-Typhus 84 + + CHAPTER III.--Description of the Contagious Typhus + of the Ox; its Symptoms, Course, Progress, &c. 140 + 1. Symptomatic Characteristics 141 + 2. Lesions found in the Bodies after Death 163 + 3. Diagnosis--Prognosis--Use of the Flesh of + Animals--Danger of direct Absorption 173 + 4. General Considerations on the Typhus, and + Recapitulation of the Symptoms 191 + + CHAPTER IV.--Treatment of the Ox-Typhus 206 + 1 & 2. Means and Measures to be employed + to resist the Causes of Contagious Typhus + of the Bovine Species 208 + 3. Curative Medication 237 + 4. Hygienic Measures to be taken against the + Extension of the Contagion--Acts and + Orders concerning sanitary Police Regulations 257 + + + THIRD PART. + + To Farmers and Graziers 281 + + + FOURTH PART. + + Suggestions on the Improvements to be effected in + the Study of Medical Science, in order that we + may be in a Condition to confront Disease generally, + and Epizootic and Epidemic Diseases in particular 311 + + + APPENDIX. + + Various Documents 337 + + + + +INTRODUCTION. + + +Everyone is talking of the CATTLE PLAGUE! But why should we +borrow this sinister and gloomy denomination from the middle ages and +from the people's vocabulary? Is this, then, an unknown and incurable +disease? Is this the first time that it has made its appearance on the +soil of Great Britain? To judge by the manner in which the diffusion of +this complaint has been met, accounted for, explained, and discussed, +one might imagine it was so; and yet the mere observation of its causes, +its symptoms, and its signs and effects on the bodies of the diseased +animals, besides a few references to the medical library, would easily +have testified that nature did not wait until the second half of the +19th century to generate a new distemper. No! Nothing new has appeared +for a long time in the worlds of space. The cosmic phenomena pursue +their perpetual course, and the organic phenomena, _à fortiori_, do the +same. Life, throughout the whole range of the animal kingdom, whatever +may be its changes and fluctuations, submits to the fixed and invariable +laws which hold dominion over health and disease. Our presumption and +ignorance alone can account for the astonishment we manifest, not only +when we witness great general calamities, but even when we look upon +those simple morbid derangements which organic matter, both animal and +vegetable, is continually undergoing on the globe, in the natural +progress of destruction and dissolution. + +The habit we most of us have contracted of confining our observations to +the phenomena which strike our eyes, instead of fixing them on the +general causes by which these phenomena have been produced; the +forgetfulness of some, in others the want of acquaintance with general +and comparative pathology, have in this instance led many conscientious +inquirers to misapprehend both the nature and the treatment of the +cattle complaint. It is in vain that we have subdivided and classed +medical science--in vain that we have arbitrarily instituted a +veterinary medicine and a human medicine; nature, in her acts, has no +such subtleties. With nature, organic matter is organic matter, life is +life; and although it may be true that both organic matter and life +become more complex, and continue to rise in perfection till they reach +man, it is quite as true that the laws of pathology and physiology are +the same in all, and that it is just as difficult to cure the typhus of +the ox as that of man. As, therefore, it is because we overlooked these +fundamental truths, that the outbreak of the cattle distemper found us +unprepared, we must treat the subject with all the gravity which is its +due. + +Let it not, however, be feared that the special fact of the _so-called_ +Cattle Plague will be lost sight of amidst a crowd of scientific +generalities. No; collateral reflections, seemingly foreign to the main +argument, will concur to elucidate it; and all these rays of light will +converge to a common centre, reflecting, we flatter ourselves, some +evident facts and practical truths. + +This work on the contagious typhus of the ox is divided into four +principal parts. + +The first part contains the history of this typhus from the remotest +times down to the present day. It is divided into several sections. + +The second part, which gives the description of the disease, is +subdivided into four chapters. + +The first chapter treats of general typhus, in order that a perfect +understanding may be arrived at as to the name and definition of the +particular distemper which affects the ox. + +The second relates to the causes and origin of the disease. + +The third treats of its symptoms, its progress, &c. + +The fourth contains its mode of treatment. + +The third part gives some plain instructions for the benefit of farmers, +cattle-dealers, and dairymen. + +The fourth part gives a development of the scientific means and +safeguards to be adopted, in order that this country shall never relapse +into that state of helpless panic to which a want of preparation exposed +it when the present epizootia began its ravages. + + + + +FIRST PART. + + _The History of the Contagious Typhus of the Ox, from the + remotest times down to the present day._ + + +I. + +General, local, and particular causes of destruction are constantly +reacting on organized creatures, and these causes account for those +_epiphytic_ diseases which infest plants, the _epizootic_ diseases which +spread mortality among the brute creation, and the _epidemic_, which +strike and are fatal to the human species. Thus it is that we +particularize at present, in the vegetable kingdom, the disease which +has attacked the vines, olive-trees, and potatoes; in the animal +kingdom, the silkworm sickness, and the cholera, and the typhoid fever +of cattle: so that we may safely say, that one or other of these +diseases is always, at a given moment, raging in some part of the globe +among some species of animal, either birds, pigs, horses, sheep, horned +cattle, or, in fine, attacks man himself. + +When, however, the peccant invasion falls only on the vegetables and +animals situated at our antipodes, we seldom hear of the ravages it +commits; and when we do, forgetful of the affinity which links together +all the organic beings on the earth and their mutual dependence, nothing +can exceed the indifference we show to these calamities. Then, when the +danger threatens us nearer home, or when the evil has invaded us, we +have recourse to quarantine as the grand preservative to shield us. But +this preservative remedy is most frequently deceptive--a mere illusion; +for the real plague, typhus and cholera, borne along by the winds of +heaven, pass over the longest distances and the highest obstacles, and +baffle all our calculations; teaching us, by their successive returns, +that we shall continually be exposed to their destructive havoc so long +as we neglect to eradicate the evil at its original source, that is, in +those countries from which it emanates. + +And this is the place to observe, that the cholera morbus threatens to +keep a permanent footing in the English possessions of India, because +the public works, by means of which the great rivers used to be confined +to their beds, have not of late been repaired and kept in good order in +those countries; owing to which neglect, their waters overflow the +plains, leaving, when they subside, those pestilential deposits which +afford a perpetual incubation to the cholera. + +We are induced to dwell thus on the general causes of these diseases, +because the sick plants, on which dumb animals feed, and the sick +animals, on which man himself feeds, have a continual relation of cause +and effect; and we shall have to refer to this subject and give it +weight, when we come to speak of the treatment of these diseases. + +It is an important fact, which deserves our most pointed attention and +consideration, that the vital resistance inherent in the animal frame to +withstand the attacks of these contagious diseases, is very far from +being the same throughout the whole kind. Man, in this respect, is the +most favoured and best fortified; he is able, without much +degenerating, to inhabit any latitude, to go with a sort of impunity, if +his calling require him to do so, amidst the most pestilential +emanations, and to continue for hours inhaling their baneful fumes. We +could quote many striking examples of this resisting power in man. But +there is one which we have recently witnessed, and which all can +appreciate. We refer to the slaughter-house of the great Metropolitan +Market. Here we saw, in lumps and fragments, every variety of corrupt +_detritus_ of animals which had been seized with the contagious typhus; +we saw the animals, too, being felled and slaughtered and dissected, in +a high temperature which rendered the air so poisonous that we could +hardly breathe it; yet amidst all this infection the workmen employed to +move and handle these revolting wrecks appeared indifferent to the +scene, and quite in their usual health. No living animal besides man +could stand such a trial; no other could breathe for hours, and day +after day, like these workmen, an atmosphere so charged with decomposing +impurities. + +We say, therefore, that man may expose himself, with less danger to his +life than any other animal, to those pernicious causes which produce and +develop contagious diseases. Next to him, with respect to this power of +vital resistance, come the omnivorous animals, then the carnivorous, and +last of all, the herbivorous, in which this faculty is very feeble +indeed. + +This prime consideration, to be fully understood and appreciated by +unscientific readers, would require explanations beyond the scope of +this work. Let us, however, for the present establish the fact, that +herbivorous animals, such as sheep and horned cattle, offer but a very +weak resistance to the causes which generate infectious and epizootic +diseases, and let us do our best to prove it by demonstration; for if +this truth be once admitted, we shall therefrom deduce that it is the +duty of man constantly to surround these frail and delicate creatures +with special care and attention, if he wishes to prevent their being +decimated from time to time, and if he would likewise avoid the +consequent injuries to himself--the loss of health and money accruing +from this deterioration. + +So long as the herbivorous or grass-eating animal is properly fed; so +long as he browses on fat pastures; so long as his blood retains those +physiological elements which are the prime condition of health, he can, +and does, resist the causes of most contagious maladies. But if a hot +summer and a long continuance of dry weather chance to curtail, in +temperate zones, the usual abundance of his fodder, then comes the fatal +change: the blood is impoverished, the secretions are debilitated, a +strange languor runs through the system, the vital resistance is +unnerved, and he becomes an easy prey to those noxious influences which +were encountered before without injury whilst his provision was +abundant. + +This is a fundamental matter. We therefore beg leave to support and +justify our argument by borrowing some additional evidence from prior +labours of ours, accomplished at the Ecole d'Alfort, near Paris, +conjointly with Professor Delafond, whose name has so often been cited +in the public journals in connexion with the cattle plague. + +All vegetables and animals; with the exception of _adult_ men, whenever +their health declines from any cause (but more particularly from +paucity of food), spontaneously generate microscopic parasites, or very +minute insects, the germs of which are inherent in their system. A flock +of fleecy animals, wasted by deficient food in dry and parched meadows, +becomes attacked in due time by a parasitical cutaneous disease, known +as the _itch_, which is enough, if not checked, to destroy the whole. +Now, all that is required is to remove this flock to a more fertile +soil, where there is plenty to feed them, and the disease will disappear +of itself without any treatment. Deficiency of food destroys the health +of animals, and abundance of food overcomes disease in them. + +A sheep affected by this parasitical disease may, without any fear, be +placed in a flock of healthy sheep, for he will not propagate the +distemper; but if instead of being sound and healthy, the flock is in a +weak declining state, this contaminated animal will diffuse the disease +with frightful rapidity, and may cause their entire destruction. These +facts may seem startling, but we are only speaking after the +incontestable authority of experiments. + +We selected six healthy sheep, which we kept well supplied with +provisions; we covered these healthy sheep with parasites (acari). On +every one of these sound, well-fed sheep, the microscopic animalculæ +died off without generating the cutaneous disease; for the blood, the +humours, and the skin of sound and healthy sheep constitute a soil +unfavourable to the propagation of these parasites, and actually starve +them to death. + +After this first experiment, we subjected these six sheep to a deficient +diet; they grew lean, their blood was impoverished, and then all we had +to do was to lay upon them not thousands and thousands of these +parasites--as we had done in the first instance--but one solitary female +in a state of fecundity; and the parasitical distemper unfolded itself +so fiercely as to cause the death of three of these sheep on which the +test was allowed to run its course; whilst the other three sheep, having +been restored in time to a recoverable condition just as they were about +to drop off, were thoroughly cured, without any special treatment, by +the sole influence of good food and ordinary hygienic attention. + +Other tests, similar to these experiments, were applied to dogs, horses, +and horned cattle. A lean and scraggy dog, covered with parasites and +eruptions, with eyes running foul humour, a dog which could neither run +nor stand, and which was reduced to the last stage of wasting marasmus, +was rescued from the jaws of death and thoroughly cured without special +treatment, by the sole influence of a rich restorative diet. This dog +afterwards became a fine hunting hound, beautiful in shape, and +admirable for his sportive attributes. + +These experiments having been submitted to the judgment of the Académie +des Sciences in Paris, were honoured with its approval, and the reports +concerning them were printed at the Academy's expense, and crowned at +the competitive examination. + +The vital resistance of horned cattle is so feeble, that those animals +which are periodically exhibited in the north of London, though +certainly chosen from among the most healthy and robust, could not herd +together in large numbers for the space of a month in the Agricultural +Hall at Islington, without sinking under infectious and contagious +diseases--almost one and all. Under the conditions in which we see them +in that Show, a single month would be sufficient to produce almost their +complete destruction; for even a single week, which is the usual +duration of their confinement, affects them so much as to render a large +proportion of them unhealthy. + +Every one knows how apt cavalry horses are to sicken and die off during +a campaign. Every one has heard of the fearful ravages amongst the +horses of the Allied armies during the Crimean war, when many companies +were dismounted owing to this mortality. + +Let us now transport ourselves in thought into the middle of those +immense steppes where vast and innumerable herds of herbivorous animals +are being bred for our supply, and consider what will be the effects on +their health and life if they should be afflicted with a scarcity of +forage, in consequence of this long dry summer. + +It is unnecessary to say that there exist in Russia, in Hungary, in +Australia, in North and South America, and in many other parts of the +globe, large tracts of country which are still uninhabited, whose +uncultivated soil supplies with food great numbers of sheep and cattle. +These spacious tracts, known as moorlands or steppes, particularly +abound in Russia, on the banks of the Wolga, the Don, the Dnieper; in +Hungary, on the banks of the Danube; and also in South America, in the +republics of Venezuela, New Granada, Columbia, &c. + +Now, in hot and rainy seasons these steppes teem with rich and luxuriant +verdure; the plants growing up in the marshes are prolific and abundant, +and even those parts of the wild moors which produce nothing but heath +are capable of feeding and fattening flocks and herds. + +Under conditions so auspicious as these, animals may still suffer, but +in what way? By excess of food, or repletion. They are in general robust +and healthy, and thus fortified they inhale without detriment the +deleterious gases of oxygen with carbon, carburetted hydrogen and the +like, exhaled by the plants which grow out of the swampy soils. Thus +protected, too, they are proof against the fluctuations of the seasons, +and against every injury which threatens them; and their strong and +sound condition enables them to sustain the fatigues of their long and +arduous journeys, and to supply the rich countries of the West with +their flesh, fleece, and hides. + +When the seasons have thus conveyed a due proportion of heat, water, and +electricity to the elements of the soil, both plants and animals conduce +to the comfort and health of man, and fulfil his expectations. But the +laws of nature are involved in mystery. Good and evil go hand in +hand--death and life travel close together--and a few years of +prosperous harvests are almost invariably followed by blight, +barrenness, and scarcity. Most men think only of the present time, and +this imprudence and want of foresight prevent farmers and great cattle +proprietors from collecting and holding in reserve the requisite stores +of sustenance to supply their sheep and oxen during these barren +seasons. Sickness then breaks out, and these helpless creatures perish +in vast numbers, to the detriment of their owners' best interests. + +And truly, when continual rains cause the rivers to overflow, when the +plains are drenched and soaked, or when a burning sun scorches the +ground, herbivorous animals wander in vain from field to field in quest +of sustenance to restore their strength, or of pure and healthy water to +slake their thirst; their vital resistance dwindles away, deleterious +gases poison and bewilder them, their blood is debased, and as Ovid +says, + + "Corpora foeda jacent, vitiantur odoribus herbæ." + +And since these mild and harmless animals, which seem to have been +created merely to clothe us, and to nourish us with their milk and +flesh, have not been endowed by nature either with the intelligence, or +the activity, or the cunning, or the invention, or the skill bestowed on +the omnivorous and carnivorous species, hard is their fate under the +pressing needs of hunger. Peaceful creatures, they browse in vain on +deleterious plants on a sterile soil; their external and internal +teguments now afford a favourable seat for the propagation of +parasites--for the _parasitogenia_; and soon after a general _adynamia_, +or relaxation of the fibres, delivers them up without resistance to the +morbific elements of the infectious diseases to which they are exposed, +where the languishing, the sick, and the rotting are herded together, +and they are carried off by hecatombs by this wasteful and devouring +typhus. + + +II. + +We may readily conclude, from these general observations on infectious +and contagious diseases, that they must have existed in all former ages; +and if in our present advanced state of civilization they are so +destructive, we may be sure that in those remote periods they must have +been, both as regards man as well as the brute creation, the cause of +general extermination, in whatever parts of the earth they prevailed. +And indeed, whenever we refer to ancient or modern history, we are +continually struck with the analogy which exists between the epidemic +diseases signalized by the general name of PLAGUE, and which +decimated all the living beings, and those which more recently, and at +the present moment, have startled the world by their fatal effects on +men and animals. + +Moreover, we cannot too often repeat the fact--in order that those +documents relating to the past which contain useful instruction may be +examined and searched into--that the physiological and pathological laws +which rule and determine the phenomena of organic matter, whether in +health or sickness, were, like the laws of chemistry, electricity, and +astronomy, originally established at the time of creation, and that +matter submits with passive obedience to the laws of transformation and +transubstantiation, which are the absolute condition of life. These are +the eternal laws of which a synthesis so admirable is furnished by the +Gospel, in this short injunction, "_Take, eat, this is my body; drink, +this is my blood._" + +Now, if man, who is the sovereign master of this matter, did not take +care to regulate and modify it for his own benefit and the benefit of +all living creatures on whom his own life depends, as well as his wealth +and happiness; if he did not seek thereby continually to diminish the +sum of evil, and to extend the sum of good which it is his mission to +increase, he would violate these laws, which are inherent in matter, and +which have existed for his use since the creation of the world. + +We must likewise believe that those PLAGUES which are spoken of +in the Bible, those which Homer alludes to, that which is related by +Plutarch, and which succeeded the general drought in 753 before Christ; +those mentioned by Titus Livius, Virgil, Ovid, and other Latin authors, +the most virulent of which plagues raged in the years 310, 212, and 178 +of the Foundation of Rome, resembled the epidemics or plagues which are +witnessed in our own day. + +The plague of 212 swept away all the inhabitants of Sicily, cattle as +well as men; that of 178 destroyed all the priests, who sought in vain +for victims free from the contagion, to offer them up as sacrifices to +the offended Gods. + +Cecilius Severus gives a most striking description of a pestilential +disease which, in 376 A.D., swept away all the cattle in +Europe. Judging from his account of that scourge, we may fairly believe +that the distemper he has described was identically the same as the one +which has just broken out in England. "A universal distaste, sudden +dejection, vertigoes, spasmodic tension in the limbs, _a painful_ +_swelling of the lower belly_, violent affections of the nerves, sudden +death--everything shows the presence of a pestilential ferment, which +irritates the solids, infects and vitiates the fluids, which is the +cause of the putrefaction of the humours, manifested by the swelling of +the lower belly, which in that case depends on a putrid fermentation so +as to disengage air." + +A piece of iron, representing the sign of the Cross, was heated in the +fire, and when red-hot was applied to the forehead of the sick animals; +and this remedy was looked upon at that time as the most effectual they +could apply. + +Grégoire de Tours makes mention of an epidemic, the result of a long dry +summer, which, in 592, was very fatal in its havoc, sparing no living +creature whatever. + +André Duchesne, in his "History of England," speaks of an epidemic +which, in 1316, during the reign of Edward II., owed its origin, on the +contrary, to a long season of rains. + +The celebrated physicians Ramazzini and Lancisi relate that in 1711, an +ox which had been imported from Hungary, that constant focus of typhus, +displayed the most deadly form of the cattle disease, in the Venetian +territory, although no alteration in the air or waters had been observed +in Italy, and the seasons had been regular and the pastures abundant. +The contagion spread into Piedmont, where it carried of 70,000 head of +cattle; thence it extended to France and Holland, each of which +countries lost 200,000 of these animals. The trade in hides introduced +the distemper into England, where it proved no less fatal. It was the +same in the other countries of Europe. + +In this disease, the intestines of the affected cattle were, as in the +present epizootia, inflamed, and strewed over with livid spots and +ulcerations, and the blood, though apparently fluid in the body of the +animal, _coagulated directly after it had issued from the vein_. + +Herment thence concludes, that this epizootia is nothing more than an +inflammation of the blood. Lancisi advised his contemporaries to put to +death without pity every animal which was affected or seemed to be +affected with the disease; and it was in England that this spirited +resolve was first acted upon. + +The three counties of Middlesex, Essex, and Surrey arrested the course +of this contagion in less than three months, by adopting this measure; +whilst in the rest of the stricken counties of Great Britain, and +likewise in Holland, where this decisive course was not taken at all, +the disease prevailed among the cattle for several years. Since that +time, it has been insisted on by some authors, that the barbarous +process of general extermination offers the most effectual remedy which, +in our present state of ignorance and improvidence, we could have +recourse to, in order to check the diffusion and the duration of this +fell disease. + +The learned Goelicke describes an epizootia which was witnessed in 1730, +at Frankfort-on-the-Oder. His narrative, written with a masterly hand, +might very properly be applied to the disease which we are now +considering; and the treatment recommended by this earnest and vigilant +observer is so wisely deduced from the symptoms, that even in the +present day we might take that treatment as a model. + +We could have borrowed much more largely from this source of +biographical researches had we not deemed that these quotations would be +sufficient for the purpose we had in view in this work. But from these +authorities we think it may justly be concluded, that infectious and +contagious diseases among horned cattle have frequently appeared from +the remotest times down to the middle of the eighteenth century. + +All these attacks of epizootia were a frequent and severe cause of +suffering and misery among animals and men; but the ravages which they +left behind them were of slight importance each time, if we compare them +with those attending the epizootia which towards the year 1746 affected +the animal kingdom. This dreadful scourge lasted ten years, and swept +away nearly the whole race of horned cattle throughout Europe. It was +closely studied and thoroughly understood in its causes, its symptoms, +and its treatment by the scientific authors of that day, and those +writers, more judicious than we, did not designate the malady by the +title of PLAGUE. This particular visitation deserves to fix our +attention in an especial manner, not only on account of its striking +resemblance to the disease which now makes us all so anxious, but +because it induced two English physicians, Malcolm Flemming and Peter +Layard, to write on this disease two accounts or statements which are +equal, if not superior, to all the volumes which have since appeared on +the subject of the Cattle Disease. There is no help for it, and our +pride must bend itself to the acknowledgment: these two men, our seniors +by a century, were men of quite another stamp. Their expositions, +enriched with quotations from the Greek and Latin authors, abounding in +facts, ingenious insights and inferences, are far superior in merit to +the multitude of voluminous works which have been written and published +since then. It would be easy to prove that these two sagacious inquirers +far better understood than we have done the real nature of this cattle +disease, and that we must be grateful to them for first opening the way +which all of us must take in order to discover the preventive and +curative means of which we are still ignorant. + +Let us observe, in passing, that these two physicians, who appear to +have been scarcely known, enlightened by the effects of the inoculation +of small-pox, then practised from man to man, appear to have first +conceived the idea, now practised in Russia, of preventing the +propagation of the contagious cattle disease by means of inoculation; +and we may raise the interest of this remark by reminding the reader +that their experiments to inoculate cattle were made in 1757, eight +years after the very year which gave birth to the future inoculation of +man with animal virus by the celebrated Jenner. By this it would appear +that the twofold honour of applying the method of inoculation as both +preventive and curative means in respect of contagion in cattle, and as +the preventive means by the variola of the cow to resist the ravages of +the small-pox in man, is the indisputable claim of English +physicians.[A] + + +III. + +Very little is known of the origin or first outbreak of the epizootia +which produced such fearful ravages in the middle of the eighteenth +century. Some suppose that it first appeared in Tartary, where it +occasioned a disorder twice as extensive in its pernicious effects as +any similar distemper which had been known up to that time. Thence it +passed into Russia, from which it spread on one side into Poland, +Livonia, Prussia, Pomerania, and Holland, and from that country into +England; on the other side towards the East, it invaded the Turkish +Empire, Bohemia, Hungary, Dalmatia, Austria, Moravia, Styria, the Gulf +of Venice, Italy, Spain, Portugal, France, the banks of the Rhine, and +Denmark. + +But another opinion has assigned Bohemia as the source from which this +destructive epizootia took its rise, and its supporters allege that +during the siege of Prague the cattle feeding in its plains had been +deprived of their usual fodder by the continual _razzias_ of the French +to supply their own cavalry. + +Be this as it may, this virulent cattle disease having at length +assumed the proportions of a public calamity, the several governments +were obliged to take it into serious consideration, and the medical +faculties and most celebrated physicians began to make it the subject of +their studies and reports. In France, therefore, the professors of the +faculty of Paris and Montpellier, suspending every other pursuit, +devoted their most assiduous care and attention to dumb animals. + +Sauvages, the Dean of the Faculty at Montpellier, drew up a most +philosophical and learned account of the prevailing disease, in which, +like Stahl, he forgot probably for a moment the part which, in the +progress of distempers, he ascribes to the soul. + +The professors of Paris, very famous in their day, but who, having left +behind them no works so valuable as the "Nosologia" of Sauvages, are now +completely forgotten, likewise addressed the result of their inquiries +and lucubrations to the King. + +Doctor Leclerc was sent into Holland, whence he brought back a Memorial, +which was a reflex of the opinions he found current in Denmark, and +which has been transmitted to us in the _Memorials of the Royal Society +of Science at Copenhagen_. + +It is evident from the reflections found in the writings of Malcolm +Flemming, Layard, and other competent observers, that this formidable +epizootia was in its character identical with the one described by +Ramazzini and Lancisi in 1711; and we feel warranted in saying, after +having examined every work of any importance which has treated of that +visitation, that it resembles the disease now prevailing among cattle, +in its march, in its symptoms, and in its gravity. We believe that these +three visitations constitute but one and the same malady, occurring at +three different periods. This appears to us a most important fact, for +if such be the case, the tentative treatment of that time deserves our +most particular attention. Consequently, a few retrospective glances may +perhaps be permitted us, in considering the subject of cattle disease. + +The medical professors (including several English physicians), who +observed and described the epizootia of 1745, divided the same into +three periods. + +The duration of the disease, when it passed through all its phases up to +the death of the affected animal, consisting of from ten to twelve days, +they usually ascribed to each of these periods or stages an average +continuance of three or four days. + +_1st Period._--After a few days of latent incubation, which the observer +could not suspect, the sick animal betrayed signs of the morbid state +which was about to declare itself, by his careless feeding, by drooping +his head, and by exhibiting the deepest dejection of spirits in his +attitude and look. Rumination, already imperfect, soon ceased +altogether, the appetite failed, the horns, ears, and hoofs were cold, +the hair grew stiff, the tongue and mucus looked white; the eyes were +tearful and fixed, the hearing obtuse, whilst, in the cows, the supply +of milk diminished. In cases of unusual gravity, transient shiverings +testified to a serious disturbance in all the animal functions. These +shiverings were followed by a violent fever, the blood became inflamed, +the breath hot, the respiration hurried and sometimes attended with +slight coughing; when, if too violent a repercussion was transmitted to +the nervous centres, the pressure on the vertebral line became +intolerable, and the animal, seized with vertigo, and almost delirious +with pain, would fall during this first period, as if struck by +lightning. + +The same phenomena are sometimes observed in the typhoid fever of man, +which offers moreover some analogy with the contagious typhus of the ox; +but as the ox and the horse have likewise the real typhus fever, they +may some day supply us with the preventive virus for that fever, in the +same manner as the cow now supplies us with the preventive virus for the +small-pox. + +_2nd Period._--In most cases the disease pursued its course with greater +or less regularity; the sick animal experienced gnawing pains or +twitchings, and spasmodic shootings in the limbs, apparently attended +with pain. His thirst was insatiable, but he had no appetite, the +functions of the bladder and intestines were impeded, then diarrhoea +supervened, accompanied with dry, fetid, and sometimes bloody excreta. +Thick viscid mucosities dripped from the nostrils, mouth, and eyes. The +dorsal regions and the loins were constantly aching, headache and +sleeplessness were permanent. The animal continued either standing or +lying down, and if he wanted to rest, he could not bend himself +gradually, but would fall like an inert mass to the ground. + +_3rd Period._--Diarrhoea was continual, becoming more fetid every day, +the wasting of flesh made rapid strides; the cellular tissue beneath the +hide was filled with gas along the vertebral channels and under the +abdomen; the nostrils were stopped up with mucosities, the animal could +only breathe through the mouth, puffing and blowing aloud as he drew in +the air; and at last pustular eruptions showed themselves on various +parts; but as this depurating crisis was insufficient, the poor beast, +in this final period of the attack, fell a sacrifice to it between the +seventh and twelfth day. If he chanced to be lying down his agony was +slow, but if standing, he would sink upon himself, and expire at once. + +In this dreadful epizootia, very few of the smitten cattle survived--not +more than four or five in a hundred; and in these favourable cases, the +symptoms presented certain signs and critical phenomena of a happy omen. +In these rare exceptions, the pulse did not exceed seventy, the +beatings of the heart were always perceptible, the patient did not +refuse to drink, the continuous fever exhibited no aggravation at night, +pustular eruptions and tumours appeared on the dewlap and the fore +limbs, and the epidermis over the mouth and nostrils peeled off about +the twelfth day. + +When dissected, the bodies offered to view the following alterations, +the same having already been observed by Frascator during the prevalence +of the epizootia in 1514, and by Lancisi and Ramazzini during that which +was so fatal in 1711. The mucous glands of the mouth were livid, and +occasionally excoriated; the bronchial tubes were obstructed with +mucosities; the lungs, besides being partially congested, were sometimes +emphysematous, that is, inflated with compressed air. Of the four +stomachs, the rumen was full of food, the reticulum, the omasum, and the +abomasum exhibited purple or livid spots, according to their place. The +thin intestine and the thick intestine showed either a general +injection, scattered livid spots, or ulcerations, according as the fever +had worn the exanthematous or typhoid form; for the mucous membrane of +the digestive channels, and especially that of the intestines, displays, +like the external tegument in man and the brute creation, divers forms +of inflammation, analogous with the measles, the scarlatina, and the +small-pox; so that, if the typhoid fever in man, which is nothing else +than the small-pox of the intestines, is so frequently cured, it is +because the general morbid condition, the fever, often conceals +different intestinal lesions, albeit they seem to be similar in the +general symptoms, which taken collectively constitute the disease. + +The flesh of these diseased animals was blackish, and devoid of blood; +the animals which fed upon it, if uncooked, sickened afterwards, or +died. The wrecks of the bodies, and more particularly the skin, +sometimes retained a strength of contagion so deadly, that the mere +exportation of them was enough to cause its propagation, and to this +cause was at that time attributed the outbreak of the contagion in +England. + +An extraordinary case of this pernicious influence, which is related by +Hartmann, who observed this epizootia at its decline in 1756, will give +an idea of the subtlety of this malignant virus. + +A farmer who had lost an ox in consequence of that virulent distemper, +buried it in one of his fields. The following night a bear smelt the ox, +raked it up with his feet, ate a portion of the flesh, and a few days +after, the beast of prey was found dead in a neighbouring wood by a +peasant in the parish of Eumaki. The skin belonging to this bear was +magnificent. The peasant flayed the animal and carried home his skin in +triumph. But his triumph was short; for that same night the poor +countryman fell ill, and died two days after the attack. The magistrates +of Wiburg, having heard of this occurrence, sent orders to have the +infected skin burned. Meanwhile, the skin had been given to the curate +of the place as a compensation for the offices of burial; but his +cupidity having persuaded him that this fine skin could not have +destroyed the peasant whom he had just buried, he did not burn it at +all, but induced another peasant to clean and dress it for him. This +simple fellow and two other clodpoles, who assisted him in the +preparation, fell ill, and all three of them died in the course of a +few days. A new and peremptory order now came from Wiburg to burn this +skin, to burn the house in which it had been dressed, to burn even the +presbytery itself, should it be deemed necessary. The skin had already +passed through several hands. However, the curate being still reluctant +to part with it, took it home again. "Can it be possible," said he to +himself, "that this skin has really proved fatal to life? What can have +been the cause, I wonder?" At the same time he rubbed it in his hands +and smelt it. Unlucky curate! A few days afterwards he himself was taken +ill and died. (_Memoirs of the Academy of Stockholm._) + +A native of Clermont Ferrand, in the department of Puy de Dôme, in +France, the birth-place of Pascal, one day finding an ox which had died +of the epizootia, stripped off the skin and carried it away. After his +return home, the black typhus, and then gangrene, broke out on one of +his arms, which had to be cut off, and the patient died of the effects +of the amputation. + +A butcher having slaughtered an ox smitten with this typhus, sold the +flesh for meat to some soldiers of the Regiment Royal Bavière, then +garrisoned in one of the towns of Languedoc. All those who partook of +this meat were seized with diarrhoea, dysentery, and fever, and +several of the sick soldiers very nearly died. The butcher, whose +avarice had caused all this mischief, had richly deserved some exemplary +punishment, and some of the sufferers proposed that he should be hanged +outright, but the majority, more clement, sentenced him to be beaten +black and blue with horsewhips. + +The popular saying, _when the beast is dead the poison is dead_, being +generally true, the virulence of the contagion, in the above instances, +possessed venomous properties of an exceptional character, for if every +sick animal slaughtered by the butchers and sold to the consumers, or +those which had been flayed for the sake of the skin, had contained so +murderous a virus in their tissues, the number of victims to the +contagion among the human species would have been appalling. And in that +case, too, similar sacrifices would be witnessed at present, for it +cannot be doubted that, in the actual state of the meat market in +London, the people are now in the daily habit of eating the flesh of +cattle which are diseased. + + +IV. + +Physicians of different countries have naturally bestowed much time and +care in considering and discussing the nature of this epizootia, because +they have felt that a satisfactory theory and appreciation of its +principal phenomena, might afford the medical faculty a rational basis +for some special treatment. + +Layard and the physicians of Geneva have considered this cattle disease +to be _a malignant fever with an eruptive tendency_. + +In the estimation of the faculties of Paris and Montpellier, this cattle +disease, considered in its symptoms, was nothing more than _a malignant +fever essentially contagious_, the action of which appeared to tend +exclusively towards the skin, and therefore it was rational to provoke +external eruptions and deposits which, as they matured, diverted from +the centre the greatest part of the morbific matter. + +_The treatment_, to which, above all, we invite the reader's attention +(more particularly that of medical men), necessarily varied according to +the period of the disease. It was sometimes preservative, sometimes +curative, as the case might be. + +_The Preventive Treatment._--The farmers and cattle-breeders, whose +herds were still exempt from the contagion, mindful of the advice which +they received through the public press, took very particular care of +their cattle during this season of epizootia: they rubbed them over with +a brush, and washed them at least once a day; they sheltered them from +the inclemency of wind and rain; they took their milch cows, which until +then they had kept shut up in unhealthy cow-houses, into the open air of +the fields; they washed and fumigated the stables; they examined the +quality of the fodder and of the other articles of food; they added +marine salt to their drinking water, or poured salt water over their +forage; and above all, they took care that no foreign animal commingled +with their flocks and herds. + +Some physicians, on their side conscious of the duty which devolves upon +them in such seasons of calamity, instead of resting satisfied with +recommending remedies, betook themselves boldly to the work, and studied +the disease experimentally in respect to its propagation and prevention. + +Thus, for instance, certain Dutch physicians, in 1754, wishing to know +whether the morbid matter would transmit the disease by inoculation, +made incisions in the necks of some oxen, cows and calves, inserting in +the wound a little tow saturated with the morbid secretions discharged +from the eyes and nostrils. This direct inoculation having been +practised on seventeen animals, transmitted the disease to them all in +the course of a few days. + +The English physicians having been made acquainted with these +experiments, applied them to a more practical purpose, no longer to +discover whether the disease could thus be transmitted (for that had +been proved), but to find out (what was far more important) whether this +fearful distemper could be prevented and kept off. + +Malcolm Flemming, in 1755, merely suggested the idea of inoculation as a +preventive means, without proceeding to a course of experiments to +ratify his opinion. He intimates his notion in the following terms:-- + +"I apprehend that inoculation will stand the better chance of bringing +on the distemper, if the subject it is performed on is as young as +safety will permit, the vessels being then most absorbent, and the +animal economy most easily put into disorder. + +"But even in case the inoculation of calves should be found so +successful as universally to prevail, the method I recommend will not be +altogether useless; for, by being properly modelled and adapted to +circumstances, it may, I am persuaded, prevent contagion, and likewise +act as a preparative in any epidemical affection of the inflammatory +kind, not only in horned cattle, but likewise in all other quadrupeds +that civil society may think worthy of preservation, and even in the +human species." + +Layard, in 1757, devotes the seventh chapter of his work, "The Means to +prevent the Infection," to the consideration of the preventive +treatment, in which he says:-- + +"No one will think of bringing the infection into any place free from +it, merely for the sake of inoculating their cattle; but if the +contagious distemper be in the neighbourhood of a herd, or break out so +as to endanger the stock, the grazier or farmer may, by inoculating his +cattle, with proper precautions, at least secure his stock, since he can +house them before they fall sick, prepare them, and have due care taken, +knowing the course of the distemper. + +"Sir William St. Quintin, the Rev. Dr. Fountayne, Dean of York, and +other gentlemen have succeeded in inoculation: in Holland it has both +failed and succeeded. These gentlemen all inoculated with matter taken +from the running of the mouth, nose, or eyes. Professor Swenke mentions +that the beast from which he took the matter was recovering from the +distemper. A circumstance to be attended to is this:--had matter been +taken after the crisis, from a tumour, boil, pimple, or scab, either on +the back near the spine, or on the legs, the pus would have proved much +more elaborated, subtle, and infecting than that which, flowing with the +mucus of the nose, must necessarily be, in some degree, sheathed by this +glutinous excretion, though I am well aware how putrid and acrid it is +rendered by the disease. + +"That nothing may be omitted which in any shape can contribute to the +success of inoculation, due attention should be paid to the constitution +and state of the beast, no less in this practice on the cattle than on +the human species. Undoubtedly the young, healthy, and strong bid fairer +for a good issue than the old, sickly, and feeble; each of these +different constitutions demand a particular treatment, even in the +method of preparation; and however trifling it may seem to many--the +urging a necessity of preparation--I will venture to affirm that I have +seen excellent effects arising from a rational preparation, and fatal +events from want of preparation. I have likewise been witness of +unfavourable turns, merely from an injudicious preparation. + +"The beasts which are sanguine require moderate bleeding; those that +have but a small share of blood must have none drawn. The strong must, +besides moderate bleeding and purging, be kept on light diet, and their +body kept open. Thus, scalded bran, mixed with their hay and chaff, will +cool them. The weakly, and such as are inclined to scour, must be kept +on dry fodder, and have peas and beans given them to strengthen them. A +mess of malt, or a quart of warm ale, with a few spices, will be very +suitable for them. + +"Whatever diseases the cattle may be affected with, if time will permit, +they are first to be removed. + +"The cattle to be inoculated are first to be well washed, rubbed dry, +and then curried, to remove all the filth from the hair and skin. Then +they are to be placed in a spacious barn or stable, where the air is +temperate and no cold can come to them. There they are to be prepared +according to the direction already given, foddered with good sweet hay, +and watered with clear spring water; and if the distemper be not near, +they may be turned out into the air, near the barn or stable, and may +stay there a few hours in the middle of the day. + +"When it appears that the cattle are in perfect health, free from any +infection or disease, brisk and lively, neither costive nor scouring, +and chewing their cud, then the operation may be safely undertaken, and +henceforth they must be confined to the barn. + +"Since there is observed to follow the greatest flow of the contagious +and putrid particles separated from the blood, wherever the infectious +matter makes an impression at first, particular care must be taken not +to inoculate near such vital parts as the heart and lungs, nor near the +womb, if a cow with calf be inoculated; for, though rowels are properly +applied in the dewlaps to draw off the pestilential humour from the +breast, and in other cases beasts are frequently rowelled in the +flanks,--yet, in this operation, as matter is inserted by these channels +into the neighbouring vessels, those vital parts, or the womb, might +become the chief seat of the disease, and the event prove fatal. + +"To prevent such accidents, human beings have been inoculated on the +arms and legs, and now-a-days the arms are found sufficient. I would +recommend that the cattle should be inoculated about the middle of the +shoulders or buttocks, on both sides, to have the benefit of two drains. +The skin is to be cut lengthways two inches, deep enough for the blood +to start, but not to bleed much. In this incision is to be put a dossil +or pledget of tow, dipped in the matter of a boil full ripe, opened in +the back of a young calf recovering from the distemper. It may not be +amiss to stitch up the wound, to keep the tow in, and let it remain +forty-eight hours. Then the stitches are to be cut, the tow taken out, +and the wound dressed with yellow basilicum ointment, or one made with +turpentine and yolk of egg, spread on pledgets of tow. These dressings +are to be continued during the whole illness, and till after the +recovery of the beast, to promote the discharge; and then the wound may +be healed with the cerate of lapis calaminaris, or any other. + +"On the third day after inoculation, the discolouring of the wound, +whose lips appear grey and swollen, will be a sign that the inoculation +has succeeded; but the beasts, as Professor Swenke informs us, did not +fall ill till the sixth day, which answers exactly to the observations +daily made in the inoculating of children. Yet the Professor adds that +on the third day a costiveness came on, which was removed by giving each +calf three ounces of Epsom salts. + +"No sooner do the symptoms of heaviness and stupidity appear than the +beasts must have a light covering thrown over them, and at night +fastened loosely. They must be rubbed morning and evening, and curried, +till the boils begin to rise; warm hay-water and vinegar-whey must be +given plentifully. Should the beasts require more nourishment, dry meat, +such as cut hay, with a little bran, may be offered. I should be very +cautious in giving milk-pottage, even after the boils and pimples had +all come out, for fear of bringing on a scouring. However, this caution +is proper, that whenever milk-pottage be given, the vinegar-whey is to +be omitted for obvious reasons. In cases of accident, the same attention +is to be observed in the disease by inoculation as in the natural way, +and the medicines recommended are the same I would use; but by +inoculation there seldom is a call for any, so favourably does the +distemper proceed through its several stages. + +"The crisis being over, it will be proper to purge the cattle, to air +them by degrees, and to have the same regard in the management of them +as is laid down in the chapter on the method of cure." + +Such are the recommendations which Layard has prescribed for those who +have to practise inoculation as a preventive treatment; it would be +difficult to offer an example of greater prudence or precision. + +A certain number of oxen were, by means of this inoculation, protected +against the attack of the cattle disease; and this mode of treatment +was, as we shall afterwards explain, adopted in Russia. Unfortunately, +this rational and preventive treatment was discovered only at the end of +the epizootia, when already upwards of six millions of horned cattle had +fallen a sacrifice to the contagious fever. + +_Curative Means._--When the first course of the disease had left no +doubt of the attack, the sick animal was subjected to an appropriate +diet, and restricted to liquids either as medicinal decoctions, or as +alimentary beverages. The decoctions consisted of whey mixed with a +little vinegar, and nitred hay. The broths, or alimentary beverages, +consisted of a decoction of bread, and of water mixed with bran and +meal, whether of barley, oats, or wheat. + +At this stage of the curative process, the majority of physicians +recommended one or two bleedings, in order to abate the violence of the +fever, and of the congestions near the nervous centres and the lungs; +and as constipation prevailed at the time, they strove with the same +object to empty the digestive passages, the intestines, and the +stomachs, notwithstanding the difficulty that exists to produce this +result in ruminating animals. + +The purgatives employed consisted of a decoction of senna, mixed with +prune juice, with a little rhubarb or fresh linseed oil, infused in +their drink, or applied as a clyster in warm water slightly salted. +Those who practised polypharmacy administered at night a mixture of +nitre, camphor, red-lead, and rhubarb, in half a pailful of warm water; +and greatly did they boast of the active influence of this beverage. + +Some practitioners even endeavoured, in the first stage of the malady, +to accelerate its action on the skin by giving for that purpose warm +drinks, and by covering the cattle with woollen cloths, to promote +perspiration; but it was generally admitted that the sick animals +preferred cold drinks, and that they were particularly fond of +acidulated whey. + +In the second period of the distemper, the same drinks were continued, +adding thereto some theriac or Jesuit's bark, in order to lessen the +frequency of the diarrhoetic evacuations. They also provoked the +depurating secretions from the mouth, nose, and eyes, by repeated +washings; and as those animals, in which the running was most easy and +copious, seemed to be less seriously affected with the disease, they +strove to increase that which flowed from the glands of the mouth by +fixing a gag in the jaws, and keeping it there for several hours. This +measure seemed so efficacious that a decree from the Parlement de Rouen, +issued on the 13th of March, 1745, ordered the application of a gag, or +bit, for three hours every day, to the cattle under treatment. + +In the third period, they sought to overcome the wasting of strength in +the system by means of tonic and nutritious drinks, decoctions of +centaury, Jesuit's bark, juniper berries, &c. They likewise administered +emollient clysters if the evacuations were bloody. + +Moreover, they placed two or three setons, principally in the dewlap, in +order to obey the signs and indications of nature--_quo natura vergit, +eo ducendum_; as a salutary and critical eruption of the skin was at +that period forcing its way. These setons were kept open with a mixture +of turpentine and yolks of egg, for the purpose of encouraging the +secretion. The purulent or emphysematous tumours were cut. + +But whatever means might be employed, almost all the cattle perished, +and the few and rare recoveries only afforded the pessimists the +satisfaction of claiming the merit of them for themselves. It was +remarked, besides, that the fattest beasts were the least able to resist +the effects of the distemper. + +It is hardly necessary to say, that during the whole course of the +treatment, great care was taken to keep both the stables and the cattle +in a perfect state of cleanliness. + +The convalescence of those animals which were cured was invariably long, +and required great attention as to their food and hygienic treatment. +Solid substances, roots, and forage were withheld until rumination +revived; and it was only after several days of encouraging trials that +the recovered animal was suffered at last to feed all day in the field, +according to his pleasure. + +Such, then, was that formidable epizootia which, in the middle of the +eighteenth century, swept away upwards of six millions of horned cattle, +and which occasioned a loss to Europe exceeding fifty millions +sterling--perhaps we might say a hundred millions--for other domestic +animals, sheep, horses, &c. (as generally happens in cases of +epizootia), had likewise suffered, in different degrees, from the +various complaints arising from inclement seasons. + +It was certainly necessary to our purpose that we should have taken this +retrospective view of the cattle disease, and it will afford us a +valuable guide for the future. We may now content ourselves with +bringing together the different annals in the chain of time which +elapsed between Layard's treatise, which was published in 1757, and the +present day. This chain of time amounts to 108 years. + + +V. + +The typhus of Horned Cattle, which had shown itself in a manner +permanent, sometimes raging at one part of the globe, sometimes at +another, could not, under the unaltered conditions by which it had been +generated, suspend its ravages; and though, thanks to her isolated +position, England may be less exposed to it than other countries, it is, +however, necessary to take note of what may serve for our instruction in +the several epizootics which will pass under our view. + +Medical writers relate that contagious typhus broke out several times in +Holland during the years 1768, 1769, and 1770; it also appeared in +French Flanders in 1771, in Hainault in 1773. In France one particular +spot was, at this period, completely rendered intact by drawing a +sanitary fence about its limits, and bestowing on the cattle particular +hygienic attention as a safeguard. The stables of these animals were +washed, cleansed, and fumigated; spring water was given them to drink, +their food was chosen with care, and a certain quantity of salt was +mixed with it. + +In 1774, Holland, a cold and damp country, was once more invaded by the +scourge; and the Government offered in vain a reward of 80,000 florins +to any one who should discover the preventive or specific remedy for the +disease. + +The typhus which, at that epoch, had likewise broken out again in the +south of France, threatened to become an abiding peril to the wealth of +nations. Two French authors, Vicq d'Azyr and Paulet, betook themselves +earnestly to the task of collecting every document which up to that time +had been published on the successive visitations of the malady, and of +offering the means of preventing it. Their intention was unquestionably +laudable, but the time for obtaining such a result had not yet arrived; +besides which, these two writers, whatever may have been their desert, +were not equal to an achievement of this character. They belonged, +indeed, to that order of men who look upon the cultivation of science +solely as a step to personal distinction. + +Vicq d'Azyr himself was but twenty-five years old when he issued, in +1775, his work, entitled, "Exposé des Moyens curatifs et preservatifs +qui peuvent être employés contre les Maladies des Bêtes à Cornes." We +should deceive ourselves if we expected to find in this exposition +anything but an interesting compilation of the works already published. + +Paulet's treatise appeared likewise in 1775, under the title, +"Recherches historiques et physiques sur les Maladies epizootiques, avec +les Moyens d'y rémédier dans tous les Cas, publiées _par ordre du Roi_." +Paris. Two volumes. + +After reading and reflecting on this title, as servile as it is +arrogant, I might have dispensed with all examination of the work. A +scientific man, whilst in the pursuit of truth, takes orders from +nobody, not even from kings. Paulet, therefore, writing _by order_, +could only produce a work of mediocrity, and such is incontestably the +degree of value of his two volumes, forming, as they do, a fastidious +dissertation of epizootics in general, and of those relating to cattle +in particular. + +The works of Paulet and Vicq d'Azyr, written at the same time, not being +the labour of men practising the medical art, are on a level as to the +notions which they have handed down to us; but that of Vicq d'Azyr +being the better of the two, we shall extract therefrom what may chiefly +interest us. + +Vicq d'Azyr relates the history of the epizootics, and expatiates on the +original cause of the typhus in horned cattle, and on its nature. The +passages in which he treats of its mode of propagation and its +treatment, are the most deserving of our notice. + +He says, that he tried to no purpose to communicate the disease a second +time to animals which had been fortunate enough to get cured. + +That cows covered with the fresh skins stripped from dead cattle, +victims to the distemper, did not contract it. + +That infected clothes which had been worn by men who had served in +hospitals where cattle were under treatment, having been laid on the +backs of several beasts in sound health, were found to transmit the +distemper in three cases out of six. + +That the gases expelled from the intestines, received into a bladder +ball, and let out under the noses of healthy cattle, have communicated +the disease to them, after ten or fifteen days of latent incubation; +and that the same gases being mixed with their drink, have also +propagated the contagion. + +That frictions, with the hands impregnated with virus, having been made +over the skin, did not produce any ill effects. + +That some oxen which had been designedly placed for a few hours among +sick animals, have afterwards been seized with the distemper. + +That a calf which had been placed in a stall containing some oxen +grievously affected, but which calf had a basket beneath its nose filled +with aromatic herbs, withstood the contagion. + +That cowsheds which had been partially cleansed and fumigated, +transmitted the disease to other cattle, even several months after they +had been vacated. + +Finally, he mentions the experiments of inoculation made by Lay and in +England, but not understanding their aim and capacity, he adds, that +inoculation does not seem to him of any use, since the inoculated +animals all died. Yet he quotes the encouraging results obtained by +Camper in Holland, who, out of 112 inoculated cattle, saved 41; and +those of Koopman, who, out of 94, cured 45 by this very inoculation. + +He reminds us that the cattle typhus is an abiding disease in Hungary +and Russia, where the beasts having bad water to drink, can only be +protected by a constant use of marine salt (_sel gemme_); but being +deprived of this salt, when they go great distances to be sold, and +being exposed to extreme fatigue and privations, the typhus then spreads +among them. He likewise tells us that Hungary and Dalmatia, which used +to supply the markets of Italy with butcher's meat, were obliged to give +up sending any cattle there, the Italians having firmly refused to +purchase the same at any price whatever. + +As regards treatment, the advice which Vicq d'Azyr gives to +agriculturists, is mostly borrowed from the authors who have written on +the great epizootics of 1711, and 1745 to 1755. Thus, he advises them to +give as drinks in the first stage, water whitened with meal and nitred; +to purge the animals with linseed oil; even to make scarifications on +the skin, and to keep up the suppuration with turpentine; to make the +animals inhale six times a day vapours seasoned with vinegar; to wrap +them over with woollen cloths; to bleed them once or twice; to +administer to them, when diarrhoea shows itself, a beverage containing +wormwood, quinine, and diascordium; to cut open the tumours containing +pus or air, etc. + +It is, as is seen, the same treatment as that quoted above; he +guarantees its success, and supports his views by the authority of Van +Swieten and Huxan. + +Van Swieten, however, had somewhat modified the treatment, by the +predominance which he allowed to acids; and this course seemed to him to +be only reasonable with respect to animals whose sick humours contain an +excess of alkali. + +Vicq d'Azyr fixed his attention on the means of prevention, the most +effectual of which, in his opinion, was to slaughter every animal which +had either sickened, or had been exposed to the influence of the +contagion; and as he insisted that the authorities had no measures to +keep in this matter of public interest, he made it a principle that the +government was bound to compensate the cattle proprietors whose animals +had to be killed--the more so, said he, that the crafty husbandmen would +never come forward and freely declare the invalidity of their cattle, +unless some indemnity were held out to them, which they would look upon +as a sort of equivalent for the benefits they had expected by cutting +them up and selling them as the food of man. + +The doctors of the period, scenting in Vicq d'Azyr a dangerous +competitor, considered the advice of exterminating the diseased cattle +as an _ingenious means of curing_ them, and as the author's age and +experience gave warrant for this satirical tone of discussion, the +public joined them in laughing at him. + +The epizootic typhus, if not so destructive, was at least as frequent in +the early part of the nineteenth century, as it had been during the +eighteenth. The armies during the wars of united Europe against the +French Republic and Empire, found it constantly in their train. Nor +could it be otherwise, the two leading causes of its prevalence being at +hand. For on one hand there was the transit of large herds from the +steppes of Hungary, and on the other the wretched hygienic conditions +amidst which the cattle had to live in the campaigning armies. + +Many books have been published of late years on the diseases of cattle, +in France and Germany; and several distinguished English veterinary +surgeons, especially Professor Simonds, have also devoted their +attention to the same subject. In the second part of this work, we shall +have occasion to refer to their labours. + +In France, Renault, Delafond, d'Arboval, Gellé, whose works enjoy a +deserved reputation, have discussed the subject of the origin of this +disease. + +Renault asserts that the disease has but one single focus, the steppes +of Russia and Hungary. The epizootics of Asia, Africa, and South America +are caused, he considers, by the importation of animals to those +countries. It is thus that he explains the epizootia which, under the +name of Delombodera, devastated the American Republics in 1832, and that +which, in 1841, appeared in Egypt. Renault thinks that neither the long +transit, nor the filthy state of the markets, nor the most wretched +feeding, are sufficient to account for contagious typhus among cattle; +that in addition to these causes, it still requires, in order to produce +and generate it among animals, a predisposition, and a special aptitude, +such as, hitherto at least, do not appear to have been witnessed except +in the progeny of the steppes. + +The other professors of his fraternity have submitted arguments to him, +which to us seem very rational; and we will endeavour to do justice to +them when we discuss the origin of the typhus which at this moment is +afflicting England. + + +VI. + +These historical dissertations and speculations on the subject of the +bovine epizootia certainly deserve to draw the attention of all who feel +an interest in the malady; but how insignificant they are compared with +the concluding facts which I have still to mention, before I at length +address myself to the consideration of the epizootia which is now +consuming our herds! + +The indisputable fact that so terrible a distemper as this typhus had +fixed itself permanently in Russia, and that it was causing incalculable +losses to the lordly proprietors of the steppes, as well as to the +government, roused them at last from their indifference. Then, indeed, +they urged the veterinary doctors to adopt some energetic means to +arrest the long duration of the scourge, and we must admit to their +honour, that various experiments which were tried for the purpose of +preventing the evil, have been crowned with complete success. Any one +may ascertain the fact by referring to the _Journal Magazin_ of Berlin, +in which the learned Professor Jessen of Dorpat has explained the +results of these important experiments. + +The Russian veterinarians having observed that the oxen which had been +cured of the typhus could mingle with impunity with the infected herds, +conceived the idea of communicating the complaint to sound cattle by +means of inoculation, and thereby to shield them from the contagion. + +The first experiments in the inoculation of _Tchouma_ or cattle typhus, +were made in the year 1853, by order of the government, in the +neighbourhood of Odessa, at the Heridin farm, by Professor Jessen. + +The first inoculative attempts were very fatal; they caused the death of +all the inoculated animals. But it was soon perceived that these +grievous results, far from prejudicing the theory, really confirmed it; +and that the virus, attenuated in its toxical properties, would prove as +effectual as was expected. And truly, in 1854 and 1855, at the Dorpat +establishment, the inoculations made with a better selected virus +afforded results less disastrous. At Kozau they were still more +satisfactory. In fine, passing from experiment to experiment, they +arrived at the conclusion that it was necessary to inoculate several +heads of cattle, the one after the other, without having recourse to any +other virus than the first inoculated, so that they might thereby obtain +virus of the 2nd, 3rd, 4th, 5th, and up to the 10th generation. The +virus thus attenuated in its morbid effects answered at length every +experiment, and oxen thus inoculated could mingle with impunity with +diseased cattle. + +At the veterinary establishment of Chalkoff they inoculated, during +eight meetings, 1059 animals with virus of the 3rd generation, and the +results were as satisfactory as could be wished for, only 60 animals +having sunk under the effects of this preventive operation. + +The inoculations made in 1857 and 1858 on an estate belonging to the +Duchess Helena, at Karlowska, in the government of Pultawa, and +conducted by the veterinarian Raussels, likewise afforded the most +satisfactory results. + +Professor Jessen thinks it certain, that beasts born of cows which have +been afflicted with contagious typhus do not contract the disease. He +maintains that Europe may be preserved from this frightful scourge, by +taking care that no cattle be exported from the steppes of Russia save +those which have had the distemper either naturally or by inoculation, +and he is striving to propagate this opinion, and to render it +practical, by having all the cattle inoculated, without exception. + +It is deeply to be regretted that counsels so prudent have not been +heeded in the 47 governments which, out of the 53 possessed by Russia, +have generated the contagious typhus; for then it would not so +frequently have effected its passage into the neighbouring states, and +England most probably, would not now have to take up arms against its +fatal extension. + + +VII. + +We here conclude that part of our labour which includes the history of +this disease, and what we have been able to glean from those medical +writers, and others, who have given us the results of their experience. +It may have appeared somewhat protracted, but it has at least laid open +to the student the antecedent investigations of our predecessors, under +calamities of the same kind, but considerably more fatal than what has +yet been witnessed in Western Europe during our time. We have +disinterred and brought to light the forgotten works of conscientious +and competent men. Like Brunelleschi, the architect, we have sought, not +to invent a theory, but to recover a practice; and thus we have received +the observations and precious facts, and finally the preventive +treatment, of other men and other times, which had coped successfully +against the cattle disease when its ravages were infinitely greater. + +To resume, then: these inquiries (which we undertook without +anticipating so rich a harvest) have proved, and made evident-- + +That the contagious typhus afflicting horned cattle, has spread its +destructive principle over our globe ever since there have been animals +living on its surface. + +That from century to century, not to say from year to year, it has +carried its terrors amidst nations and peoples. + +That the remedial measures which had been taken and applied prior to the +middle of the eighteenth century, were utterly powerless either to cure +this disease or to prevent it. + +That at that period appeared two English physicians, men of remarkable +aptitude and penetration, one of whom, Malcolm Flemming, laid down in +theory the bases of a preventive treatment; whilst the other, Peter +Layard, applied this theory to practice, by inoculating sound and +healthy animals with the morbid virus of the typhus, in order to protect +them from the fatal effects of the contagion. + +That this all-important progress in medical experience, has been +absolutely forgotten; so much so, indeed, that the experiments of +inoculation, tried in Russia only ten or twelve years ago with perfect +success, do not seem to be connected by any link with those made in +England a century before, and that the invasion of the so-called +CATTLE PLAGUE in 1865 seemed to some men to have introduced a +new scourge, which men were not armed and prepared to meet--which they +were powerless to cure, or to stay in its progress. + +These inquiries, then, have proved, we think, that we are not so +helpless as we had imagined to resist the evil. But we cannot help +feeling, that we have laid bare in this exposition some most distressing +inferences concerning the human mind. For, in truth, can anything be +more deplorable, than thus to see the civilized nations of Europe +endure, from century to century, these reiterated outbreaks of cattle +typhus, and to see likewise that no man of sufficient energy and +independence has yet arisen to tell the truth fearlessly to the +governments and peoples, however painful that truth may be, and to +expose the futility of the measures hitherto employed to arrest the +scourge? + +And, on the other hand, is it not most afflicting to see discoveries of +indisputable value buried out of view, submerged in public libraries, +utterly unknown and forgotten, like their authors, to such a degree, +that the distemper which they have made known in its entirety, and which +is as old as the world itself, seems to us almost new in 1865? + +God send, that these cruel trials and severe lessons which the past has +bequeathed to us may teach us something for our benefit! May the +irresistible might which is derived from the auspicious union of capital +and intelligence supersede the vain and flimsy efforts of isolated +energy! May the government, which lavishes hundreds of millions upon the +destructive engines of war, devote some portion of its ample means to +the study of hereditary infections and contagious diseases! For these +fatal epidemics decimate men as well as cattle, and we may at least ward +off from our children the desolating disease which at present afflicts +ourselves. + +We possess already every requisite means to protect ourselves from the +formidable visitation of these diseases: we have science; we have the +men who cultivate and teach it; we have the experience of the past +added to our own. To-day, we are called upon to resist the baleful +effects of cattle typhus; but another epizootia may come to-morrow, and +strike our horses and our sheep--those domestic animals which constitute +our most precious possession. The cholera hovers about us. If we do +nothing, if we talk and debate instead of acting, these scourges will +come upon us on a sudden, and find us quite as helpless as ever to +resist their sway. + +These palpable truths deserve to be further developed, and will be +treated more copiously at the end of this book. They will constitute the +complement of our work, necessarily written in haste, since the danger +we had to expose was itself so urgent and alarming. + +FOOTNOTES: + +[A] To assist the researches of other inquirers on this vital subject, +now so generally interesting, we may add, that the cattle treatises +already referred to--of Malcolm Flemming and Peter Layard--are to be +found in the Library of the British Museum, bound together in a single +volume, which is certainly worth ten times its weight in gold. It +contains, indeed, eight different opuscula, all relating to cattle +complaints, which scientific students may consult with real +gratification. I will here transcribe the titles of the most important +of these treatises, the pregnant expositions of the two English +physicians above-named. + +That of Malcolm Flemming: + +"A Proposal, in order to Diminish the Progress of the Distemper among +the Horned Cattle, supported by Facts. London, 1755." + +That of Peter Layard: + +"An Essay on the Nature, Cause, and Cure of the Contagious Distemper +among the Horned Cattle in these Kingdoms. London, 1757." + +A great many accounts, treatises, and expositions on the same subject +appeared at the same time in France, Holland, Denmark, and Switzerland. +One, which appeared in the last of these countries, is entitled: + +"Reflexions sur la Maladie du Gros Bétail, par la Société des Médecius +de Genève. 1756." + + + + +SECOND PART. + +This Part is divided, as already stated, into four chapters. + + + + +CHAPTER I. + +_On Typhous Diseases in general, and the Typhus which affects the Ox in +particular._ + + +By following the example of those authors who have described the +contagious typhus of the ox, we might proceed at once to explain its +symptoms, and go directly to our purpose; but, by taking this hasty +course, we should expose ourselves to be imperfectly understood by the +majority of our readers, and to leave certain doubts in the minds of +physicians as to the nature of the disease and the propriety of its +treatment. + +All animals, including man himself, are born with a predisposition and +liability to contract a certain number of contagious febrile diseases; +they bear in a manner a certain number of physiological elements, which +might be called latent germs, and which, under given conditions, become +the leaven of these diseases. This must, indeed, be the case, since +after these disorders have been once developed those who have been cured +of them are not apt to contract them again, the morbid developments +having destroyed that natural aptitude which had previously existed to +undergo the morbid action of the contagious virus. These diseases are +not numerous; they constitute a very distinct class, and the same laws, +which regulate the phenomena in one of them are applicable to all the +rest. + +These diseases exhibit the following characteristics: 1st, a period of +incubation, during which the whole economy, more particularly the blood +and humours, experience very important changes and modifications; 2nd, a +febrile state, which varies in its continuous or intermittent types, and +in its intensity, according to the species of the animals, and which +proceeds from the alteration of the blood; 3rd, a revulsion at once +toxical and congestive towards the nervous centre, inducing _stupor_; +4th, a flux of mucus from the mouth and chest; 5th, a more intense, +congestive, and inflammatory flux or discharge from the external or +internal teguments--the skin or the mucous membrane of the digestive +channels; 6th, a period of adynamia and dejection, with a tendency, in +some cases, to a critical or salutary rejection of the morbid matter by +the development of tumours or abscesses in the skin; 7th, they are at +once infectious and contagious, epizootic or epidemic; that is to say, +they are transmitted in different degrees by contact, by inoculation, +and at a distance by the means of vitiated air; 8th, finally--and this +is their leading characteristic--_they are not subject to recurrence_, +each individual that has once been affected, losing in general all +aptitude to contract the disease a second time. + +This last characteristic, when well understood, ought in reason to +induce us to have recourse to the preventive treatment, and such has +been the case with respect to the most virulent amongst them--small-pox +and the typhus of the ox. + +Prompted by these principles, which are as logical and fixed as any +mathematical deduction, I suggested in 1855 that inoculation should be +applied in typhoid fever, which is nothing else but the equivalent of +intestinal small-pox, in order to prevent the disease in men. But if the +simplest truth sometimes requires a contest of ages before it is heard +and understood, I could not hope to fix attention on a fact which might +be taken as problematical. I felt that I was outrunning time, and that I +should neither be heard nor understood; and so it has proved. + +Be that as it may, these typhous diseases have, as is seen, their laws +and foreseen development. They attack animals generally, but chiefly +herbivorous animals, endowed, as we have shown in the first part, with a +vital resistance which is, relatively speaking, very inconsiderable. + +These febrile typhous diseases (whether their development is caused by a +spontaneous morbid action in the patient or by an evident contagion), +have a period of incubation during which the vital strength undergoes +latent morbid modifications, though not sufficient to indicate, save in +times of epizootics and epidemics, the particular form which is about to +reveal its symptoms in the course of a few days. This period of +incubation being over, the mouth and chest become affected, and fever +declares itself; and then the _materies morbi_, which is to become the +special and dominant characteristic of the distemper, is directed either +to the skin, or to the digestive mucous membrane. In the first case, we +see evidence of exanthematic diseases, which present only the lightest +forms of detersive disorders, such as measles, scarlatina, or that more +serious one, from its pustulous form, the small-pox. In the second case, +the elimination takes place from the intestinal canal, and then we see +produced in animals, as well as in men, the typhous diseases: that is to +say, the typhoid fever--a pustulous and ulcerous malady of the +intestines--or the common typhus of the hospitals, prisons, and +campaigning armies; and again, in animals, there is also the typhus of +the steppes, of the marshes, &c. + +The Eastern pestilence, the plague of Rome in the age of Antoninus and +the plague of Athens, which might have given to Hippocrates the right +of treating with Artaxerxes as one potentate treats with another, ought +perhaps to be classed among those typhuses not subject to recurrence. + +As for the _cholera_, it seems to be a contagious and epidemic disorder, +of a distinct and particular kind. We are ignorant of its essential +cause, its nature, and its mode of treatment; and although it has +prevailed in every age, and even frequently of late years, it will +always, by reason of the strange formation of our medical institutions, +find us as weak and defenceless to resist its attack as we have ever +been. + +If we have been properly understood, typhous diseases are, above all, +general febrile affections. At one time the _materies morbi_, or +discharge, affects the skin; at another, the digestive mucous membrane. +When it acts upon the skin, as clinical observation shows, there is +sometimes a sort of hesitation in the eruptive process; people wonder +what disease is coming forth; the eruption wavers in the form it will +assume, till at length its real character is determined. The same +uncertainty prevails when the intestines are affected. Sometimes the +exanthema is merely the equivalent of simple measles or scarlatina of +the intestinal mucous membrane, and many typhoid fevers of short +continuance are nothing else in their nature. The same occurs in common +typhuses. Sometimes the local affection proceeds as far as pustulous +eruption, sometimes only to exanthematic rubefaction; hence the various +alterations which we have witnessed in the intestines of cattle killed +in our presence at the slaughter-houses of the Metropolitan Market, and +which we ourselves dissected. The experienced Professor Bouley, from the +Ecole Vétérinaire of Alfort, near Paris, whose visit must have been +beneficial to England, clearly recognised in an ox which was slaughtered +and dissected at the Metropolitan Market, the genuine pustule of typhoid +fever. But in most cases, as we shall show, it is the other forms which +prevail. + +We make these observations in order to anticipate the objections of +those reasoners who, being more influenced and guided by the local facts +and by the symptoms, than by the general phenomena of comparative +pathology, might argue that such or such fact is opposed to our +doctrine. + +In a word, then, typhous diseases have their types; but the living being +is subjected to so many different influences, hereditary, idiosyncratic, +climataic, hygienic, &c., that by the side of one subject going through +the course of morbid phenomena with fatal regularity, another may be +seen in which such or such functional derangement is readily +distinguished. Thus in some animals, predisposed thereto by prior +disorders, the morbid action originally propelled towards the channels +of respiration will continue to be most salient; and after dissection +the lungs will be congested and emphysematous, and the intestines +relatively but scarcely altered. The animal, indeed, though bordering on +typhus, will sink under the effect of functional derangement in the +breathing passages. In others, by the influence of some particular +predisposing cause, disorders of the nervous centres will be signalized; +a cerebral and spinal pains will be intolerable, delirium will quickly +ensue, and the asphyxiated patient, if a man, will succumb in the course +of a few days; or if an ox, he will be wild and ungovernable, and then +fall as if thunderstruck, fastened to his stall. Finally, in other +cases, these first two phases of the distemper will not prove fatal, the +intestinal injuries will pursue their course, and the affected animals +will not die until the third period. + +As we have seen, the morbid phenomena may be different, although the +affection continues the same; the typhoid fever or the typhus being +nevertheless the essential disease which prevails. + +These generalities, to some readers, may appear irrelevant, but let them +not be mistaken; they have a claim to our notice, and are really +important. They show, indeed, that independent of the preventive +treatment, which is an absolute rule in the case of virulent, +contagious, and non-recurring diseases, the treatment of the disease +itself, when it has declared itself, and when it pursues its course, +cannot be the same for every patient; and that, moreover, this treatment +must vary in the different phases of the disease, as physicians and +veterinarians are well aware. + +These generalities, likewise, explain the various diseases--viz., those +in which the animals blend together the typhous and exanthematic +diseases. The measles and the scarlet fever, affecting the external or +internal membranes, are like the first steps of these maladies; they are +generally slight, and we have but to watch over the progress of the +symptoms, and to assist nature, which, with few exceptions, brings all +things to a favourable issue. + +These disorders, which are relatively slight and do not provoke in the +economy any of those changes which in some sort transform the +constitution, are not absolutely proof against relapse. They lead us +rationally and by degrees to the more infectious and contagious +diseases, to the common typhus; therefore it is unnecessary to apply the +preventive treatment to them, that being exclusively reserved for the +latter. + +Let it then be well understood, that the typhus of the ox, the study of +which we are about to enter upon, may vary in its symptoms and +post-mortem appearances, without losing thereby the characteristic mark +which renders it a thoroughly distinct, and, in the present day, a +thoroughly well known distemper. + +Now that the reader possesses these general notions of the Contagious +Typhus, we shall be able to speak to him in a language which he will +understand, and give a definition which he will be able to judge and +appreciate. + +The typhus of the ox, then, is a _virulent, contagious, febrile, and +non-recurring disease, with stupor and derangement of the nervous, +respiratory, and digestive functions; leaving various changes in the +respective organs of these functions, and chiefly in the intestines_. + +This new definition seems to us to be more faithful and just than those +hitherto given; and this, if needed, we could demonstrate. + +I do not disguise from myself that some of the opinions expressed in +these generalities may, at first sight, appear strange and liable to +objection. Thus, it may be argued that inoculation as a preventive +treatment of typhous maladies is far from being a general law, +applicable to every case; since in Russia, for instance, where this +inoculation is practised every day, it completely fails in certain +foreign herds, and they die of the consequences of the operation; and +that this, therefore, might happen in England. + +To these objections we would reply, first, as regards the novelty of +opinions expressed, that we have taken up the pen, because we had to +write something different from what has already been published in known +works, otherwise it would have been our duty to remain silent; and +secondly, as regards the inefficacy of inoculation, that organic and +vital phenomena have their principles and their laws, which are fixed +and invincible, from which it is reasonable to deduce consequences and +positive rules of conduct, which cannot yield to superannuated opinions +or imperfectly executed experiments. To institute experiments indeed +under the rigorous conditions of a logical and irrefutable +demonstration, is not so easy a matter as may generally be thought. + +For our part, the principles deduced from strict observation are the +basis on which we build, and if it so chance that we are baffled in our +experiments we vary them indefinitely; and if still we are deceived in +our hopes, we ascribe the miscarriage to our impotence, to inadequate +means, and to the defective instruments which the physical and chemical +sciences, still in their cradle as regards organic matter, supply for +our use. Above all, we wish it to be remembered--"_Scribo nec ficta, nec +picta, sed quæ ratio, sensus, et experientia docent._" + + + + +CHAPTER II. + +_The Origin and Causes of the Ox Typhus._ + + +I. + +I have drawn my conclusions as to the preventive treatment of typhus in +the ox, from the knowledge I had acquired of its morbid phenomena, its +nature, and its non-recurrence; and it is a logical deduction quite as +accurate as could be the result of a syllogism. The study of the origin +of this typhus, and of the causes by which it is generated and spread +abroad, will supply us with additional arguments to sustain this +deduction, as well as those signs and indications which are the very +foundation of curative treatment. The description of the disease will +contribute to the same result; for the rational treatment of a distemper +can be derived only from a knowledge of all the phenomena which occasion +it, of the functional derangements, and of the alterations observed in +bodies after death. + +I wish particularly to say at once, in entering upon the subject of +etiology, that the special works which treat of it contain precise +information as to the causes and origin of the typhus in horned cattle; +and that the chief organs of the press in every country--those ephemeral +encyclopædias in which unfortunately so much vital force and +intelligence are dissipated--have published articles of the highest +interest on this subject. It would be physically impossible for me to +begin again a bibliographical labour similar to the one exhibited in the +First Part, in order to afford due justice to each of these public +writers, who have met the epizootia on the confines of their country and +fought hand to hand with it. This work is not susceptible of so much +enlargement. Let it be well understood, that I claim no other merit than +that of discussing these questions of etiology, in that order and with +that common sense which fix ideas firmly in the mind--which, if I may +use the term, _photograph_ them on those parts of the brain allotted to +the memory and judgment; also of drawing from known and admitted facts +more rational and practical conclusions than those which have been +current up to the present time. + +Much has been already said and argued on the origin of the contagious +typhus which affects the ox; some adhering exclusively to the special +conditions observable in the breed of those oxen which are reared and +fed on the steppes of Russia and Hungary; others, more reasonably, as it +seems to us, ascribing it to the hygienic conditions generally, that is +to say, to the climate, the season, the feeding, &c., &c., amidst which +these animals are living. + +All these discussions upon what has been said and argued on this subject +have been very useful. For, had it been rigidly proved that the oxen of +the steppes, by some peculiar organization, carry within them those +germs or physiological elements which at given times become the leaven +of the distemper, and, at a subsequent period, the elements of the +contagion, then, indeed, a fact of capital importance and prominent +authority would have been established, and the attention of all men +interested in these inquiries would have been exclusively concentrated +on that particular race of animals and on those countries smitten with +the curse, in order to arrest and confine the disease within its one and +only focus. + +The supporters of this theory, concerning the first circumscribed origin +of the typhus, maintain that all the epizootics whose deplorable history +we have given in the first part of this work, have had no other +generative causes than the propagation of the complaint, born and +begotten on the banks of the Wolga and the Danube, and subsequently +conveyed to the different parts of the earth by the emigration of the +cattle. And in this manner, too, they have accounted for the appearance +of the typhus in South America, in Africa, and in Asia. + +Since this doctrine on the origin of the typhus has been conceived and +maintained by men of a high order of understanding, we must suppose that +they had been struck and convinced by important facts and serious +reasons; and as it would be unfair to oppose a plain denial to an +opinion now so generally adopted, we are bound to say in what manner +these authors justify their views, after which we shall endeavour to +refute them. + +The partisans of the circumscribed origin, who make it depend +exclusively on the peculiar organization of the race of the steppes, +have based their argument, peremptory and unanswerable as they imagine, +on the prime fact, that it has always been possible to trace the +diffusion of the typhus in a given country, to some sick animal of the +steppes conveyed to that kingdom. In this manner it is, that they +explain the generation of the epizootics which have so frequently wasted +the continent of Europe. On whatever point of the globe they may appear, +this, and only this, is the source of their existence. The isolated +position of Great Britain is made to support their arguments. "Behold," +they exclaim, "Great Britain, which, thanks to its surrounding seas, has +escaped most of the epizootics which have desolated France and Germany +during the early part of the nineteenth century." Nay, more, the present +visitation of the distemper is also seized upon to sustain their theory, +since certain oxen, natives of the steppes, appear to have imported it +into London. + +We must add, that nothing is wanting in order to prove this assertion; +for they relate with perfect regularity, and step by step, the course +taken by the contagion; they specify the time occupied on its passage, +and even the names of the infected vessels which have thus imported the +principle of the typhus. + +It must be admitted that all the facts thus stated are indisputable; we +acknowledge as true, that the bovine race of the steppes has conveyed +into other countries the contagious germs of the disease; we admit that +its dissemination may be thus accounted for. + +But to admit this fact, and to draw from it the conclusion that the +bovine race of the steppes alone is capable, by some particular and +distinct organization, of developing the original typhus of the ox, and +that this typhus has no other focus on the earth than the banks of the +Dnieper and the Don, does not appear to us a sound logical deduction. +And as, if this conclusion were positively recognised, we might see but +one side of the evil, and deduce very serious consequences therefrom, it +is necessary to receive these facts for what they are worth, and no +more. + +Let us first observe, that those writers who ascribe the contagious +typhus to the race of Southern Russia, do not take into consideration +the epizootics of this typhus, the account of which has been handed down +to us by the ancient authors of Greece and Rome; and that they refer +just as little to those which are quite as frequent in the republics of +South America as on the banks of the Dnieper. For even if we allow that +once, and only once, one of these epizootics may be traced to the +arrival of a ship containing oxen brought from the steppes, how, on the +other hand, can we believe that all other epizootics have had such a +fortuitous cause to generate it; consequently, the typhus, in these +cases, must have been locally developed and diffused among American +cattle? + +Moreover, we seek in vain for the reasons which would authorize us to +assign to the bovine race of the steppes a particular organization, +rendering it alone fit to engender the typhus. But let us grant for a +moment, that the Russian and Hungarian oxen constitute a peculiar race, +as their framework and the length of their horns would seem to imply; +this much being conceded, it still remains to be shown in what respect +their anatomical and physiological structure differs from that of other +animals to such an extent as to render them alone liable to originate +this fatal typhus. + +Oh! if it were true that the bovine race of the steppes alone could +engender the typhus! we would hail the fact with joy, and would show +without much exertion of reasoning that, in that case, we possessed not +only the means of preventing the disease by inoculating sound and +healthy cattle, but the far more important means of sweeping it for ever +from the earth, by at once exterminating that cursed race, smitten with +the original predisposition of this plague; and as, after all, the +murderous scourge of the typhus of the steppes has already cost, and may +perhaps continue to cost the various nations of the Old World millions +upon millions, they would feel that their most urgent interest would be +to come to an understanding (nor would the sacrifice be too much for +their resources) so as to destroy and extirpate the evil at its original +source. There would then be no difficulty in raising up a new breed of +cattle in those countries, by transporting to it those of other nations +free from the infection. + +But who does not understand that this heroic sacrifice would be +illusory, and that the foreign races, modified in time in this new +medium, would regenerate the typhus; so that the double sacrifice of +extermination and indemnity would have been made to no purpose? + +We wish we could adopt this hypothesis, so simple and so consolatory, of +the circumscribed origin of the typhus, and its exclusive propagation +through the race of the steppes; but our mind is altogether opposed to +that view, and for the following reasons, amongst others:-- + +If the bovine race of the steppes alone could produce the typhic virus, +by reason of a particular organization which is the prime condition of +its existence, _this race alone would of necessity be fit to receive its +taint_ by the influence of contagion. But if the other animals of the +same species, as unfortunately too surely happens, can receive the +principle of the disorder, develop the ailment, and die of its effects, +then the reasoning of our opponents is faulty from its source; and it +must be admitted that all horned cattle are apt to generate the typhic +virus in those countries which afford the conditions of its production, +and that this exclusive predisposition as it is called, attributed to +the race inhabiting the steppes, is simply a chimera. + +But arguments are seldom exhausted even to defend a bad cause, and it is +objected that the fact that all oxen may contract the typhus transmitted +by the contact of animals from one to another, does not prove that the +original predisposition is the same in every race; and they persist in +maintaining--1st, that the typhus of the steppes is alone able +originally to beget the disease; 2nd, that having thus begotten and +produced it, it becomes, after this organic conception, apt to be +transmitted to every animal, and fit to be assimilated with them. + +To these subtleties and argumentative refinements it would be as easy +for me to oppose abstract reasonings equally strong, as it would have +been for the Jansenists and Mollinists, had it so chanced that they had +been drawn into a debate on the origin and nature of the virus of the +plague which carried off Jansenius. But let us confine ourselves to +serious facts and conclude-- + +1st. That we have no proof of any anatomical and physiological +difference in the humours or in the blood--that is to say, in the +organic, intimate, and biological elements of the individuals which +collectively constitute the bovine species. + +2nd. That we have a right to believe, that all horned cattle are apt to +develop the typhic virus when they are placed within the conditions +required for that effect--that is to say, when they are exposed to the +special morbific causes which form its condition _sine quâ non_, and +which are met with on the banks of those great rivers which water +Southern Russia and Hungary, in Africa, on the banks of the Nile, in +South America, on the margins of the lakes, and in what are called hot +climates, &c. + + +II. + +But if the origin of the typhus cannot exclusively depend on the +peculiar organization of certain individuals of the bovine species, we +must inquire after and search for the real causes which produce it. + +We have explained already, in the First Part, what alterations organic +matter undergoes in general, when accidental causes happen to modify its +organic elements; and we have pointed out the fact, that of all living +creatures herbivorous animals were those that offered the least vital +resistance to the causes of disease and destruction. + +This unquestionable fact being taken for granted, let us now consider +under what conditions live the multitudinous herds of horned cattle +which in Russia and in South America are reared and supported solely for +the produce of their flesh, and sometimes, too, for that of their hides. + +The great breeders and proprietors fix the number of their heads of +cattle according and in proportion to the quantity of the pastures, but +like other men, they mortgage the future for their benefit without +making due allowance for accidents or extreme changes of weather, as +when years of unusual drought succeed those of heavy rain; so that these +herds, by the single fact of these extreme fluctuations in the degrees +of temperature, are exposed to a multiplicity of causes productive of +disease. The same nature which generates life and health generates +disease and dissolution, and when the former are neglected the latter +will prevail. + +In the prosperous and favoured countries of the temperate zone, such as +England and France, these extreme variations in the seasons, which are +always the cause of a deficiency or alteration in the production of +fodder, are equally the cause of the numerous epizootics which attack +all the herbivorous species, and particularly those to which oxen fall +victims, such as the tumourous typhus (_le typhus charbonneux_), the +so-called aphthous fever, the contagious peripneumonia (which is not +liable to return and is prevented by inoculation), parasitical cutaneous +disease. + +But in less favoured countries, in those which are damp, argillaceous, +swampy, inundated by the overflows of their lakes and rivers, or by the +reflux of the sea, there is deposited a slimy or brackish water, which a +temporary torrid heat afterwards causes to ferment; and then a +superabundance of life, a teeming vegetation, springs up in all +directions. In the midst of this swarming vitality live and thrive an +infinity of worms, maggots, animalculæ, insects, mollusca, fish, +reptiles, birds, &c.; and here, too, all these creatures die and decay, +when this slime, the prolific source of generations which we might look +upon as spontaneous, begins to dry up and disintegrate. Then from these +organic vegetable and animal matters, in a state of decomposition, +escape those deleterious gases, such as hydrogen, carbonic oxide, +nitrogen, carbonic acid, sulphuretted hydrogen, and even phosphoretted +hydrogen. + +Often to all these causes of infection are added myriads of +grasshoppers, which cover the ground, where they die, aggravating the +mass of pestiferous vapour which fills the atmosphere. Finally, the +water which slakes the thirst of the herds of cattle is corrupted; the +plants on which they feed distil poisons; the air, the water, and the +plants, carry within them a principle of venom and death. After this, +how can we be surprised if this flood of putrid emanations is +transformed into a contagious typhic virus, whose subtle and +pestilential effluvia are conveyed by the ox to considerable distances? + +In fine, let us recapitulate in our minds all the causes of destruction +to which these passive creatures are exposed, and we shall acknowledge +that there is no necessity to attribute to them a peculiar organization +in order to understand the development of the typhus, which, at a given +moment, cuts them all off; and that in the deltas of the different +countries, as well in Asia, Africa, and America, as in Europe, are to be +found those conditions of infectious disease which we have described. In +these causes, and only in these causes, or in those which resemble them, +will rational men seek for the principle of the contagious typhus in the +bovine race. + +Moreover, who is there who does not understand that what is true with +regard to cholera is likewise applicable to this contagious typhus? The +cholera, for causes analogous to these, subject to the particular state +of the soil, is generated, not exclusively, it is true, but most +frequently, on the banks of the Ganges, in the same manner as the +contagious typhus is developed in certain countries where its natural +focus is found. + +The race of animals which exists on this deadly and destructive soil is +an instrument of incubation for typhus, not in consequence of their +peculiar structure, but because the conditions under which they live +condemn them to this fate. + + +III. + +Now the breeding of cattle, and the feeding and fattening of them for +the market, constitute a branch of industry--a great interest. They all +have to be removed, conveyed to various distances, and sold; so that +this traffic becomes a new cause to be added to all those which foster, +develop and propagate the distemper. + +In prosperous times, when the seasons, conformably with our wishes, have +pursued a course which we call regular (for we are fain to believe that +the planets turn on their axes on our account), and when the cattle find +the ground covered with rich pastures, and limpid streams--conditions +which are eminently favourable in themselves, though in Hungary it is +necessary to add gum, salt, mineral water, and arsenic acid, before the +health of these animals is satisfactory,--then the cattle breeders make +their sordid calculations, and select the heads of cattle intended for +sale. + +With animals, as with man, health is but relative, not absolute; the +healthiest in appearance often bearing within its frame the fatal +principle of no distant death. Fatness not being by any means a sure +sign of vital strength, many of these cumbersome beasts, though +seemingly in good and sound condition, contain in their systems, in +various stages of incubation, the tainted leaven of contagious +affections, such as peripneumonia, or even the typhus itself. + +But, regardless of this liability, their sale and migration are resolved +upon at length. Hitherto these harmless creatures have lived in the most +perfect stillness and retirement. Their calm, monotonous life has been +as regular as the course of time; never by a single pulsation have their +hearts exceeded the wonted number per minute; they are all gifted with a +nervous sensibility of which the vulgar have no notion. Some favoured +few have felt the sympathy of friendship for the herdsman who tended +them, and for the companions with which they fed. They have been leaders +of their own herd, they have marched at their head; they have given the +signal when to seek shelter beneath the trees, or when to repair to the +brook. They have loved the fields amidst which they have grown and +thriven. Some of them, reared and fed beneath the domestic thatch, were +grateful for the care they had received; their master was endeared to +them, they would run to meet his coming, answer to their name, and lick +his hand with fondness. + +And it is the course of this tranquil, this happy existence, that is +about to be broken abruptly. It is this creature, the pattern of +gentleness and goodness, that we are going to treat like a heap of +insensible and inert matter--which we are going to subject to +unutterable torture! + +And now, indeed, these creatures are all at once handed over to the +savage guidance, to the thongs and cudgels, of a hind, whose cruelty +keeps pace with his stolid ignorance, and who abets his dogs to quicken +their course to the neighbouring market. From this moment, half-fed and +athirst, these poor animals are forced to make long journeys afoot; or +since the construction of railways, to be heaped together confusedly in +a locomotive pen. There, the shaking, the sudden starts, the friction of +five hundred wheels on the rails, the horrid snorting of the engines, +alarm and terrify them to such a degree as to turn the whole mass of +their blood. + +In such a state of vital prostration or feverish excitement, entire +herds are carried to the public markets or to annual fairs with other +animals, and nearly all sent to the shambles. But some amongst them are +reserved for another fate. The females, for instance, are set apart to +serve as milch cows; and in this manner they carry with them into the +cowsheds, wherein they are received, the taint of those contagious +distempers, the germs of which lay concealed in their frames, or which +they have contracted from the companions of their journey. + +Some of these heads of cattle, starting from the steppes of Russia, have +to travel five hundred miles in an open cage, less cared for and +protected than bales of merchandise, exposed to the rain, to the heat +of the sun, to sudden changes of temperature, to cold and cutting +draughts, increased by the rapid motion of the train;--these animals, +foundered, prostrate, panting with fever and torturing pains, still have +to undergo new trials, if they cross the sea. In this case, the wretched +victims are violently expelled from the locomotive, rocking sheds of the +railway; a leathern strap hanging from a crane lifts them into the air, +and lets them down into the mid-deck of a ship, where they are crowded +as closely together as possible, for here, too, space is very costly. +Finally, the vessel gets under way and ploughs the ocean; contrary winds +beat it about in every direction, and these poor creatures have to +endure a new kind of torture, accompanied by the intolerable pangs of +sea-sickness; and in this state it is that they alight on the British +soil, and are driven off to the different markets. + +It is useless to expatiate at length on the state of general derangement +and disease in which these oxen reach their final destination. Some +amongst them have endured for eight or nine days these unspeakable +tortures, without being sustained by nourishment--for no animal, when +his spirits forsake him, can assimilate his food amidst all this +physical suffering and so great a shock to his nervous system. + +Let us here declare that these animals, though removed from their +meadows with all the signs and appearances of sound health, at a time +when a fine season had been productive of abundance, and when no +epizootia was raging in the country which they have left, may +nevertheless bear within them the taint of contagious typhus; and let us +ask ourselves what must come to pass in those disastrous years when this +typhus prevails under the influence of those destructive causes which +were passed in review just now, and when the Russian and Hungarian +proprietors, eager to forestall an inevitable general calamity, hasten +to send off to Italy, France, Holland, Finland, or to the ports of +England, many animals already seized with typhus, and whose virus must +have acquired infectious properties still more intense and deadly under +the influence of the deep disquiet and commotion which the removal and +conveyance of these animals, under conditions so deplorable, must have +produced in their frames. + +Such are indeed the pernicious conditions in which oxen may be, and +often are, dispatched to England; and such appears to be the real cause +of the outbreak of the spreading epizootia which we witness at this +moment, and which has created so much alarm in so many counties of +England.[B] + + +IV. + +Let us now consider this contagious typhus in its destructive extension +over the British soil; let us study and examine the causes of its +diffusion as they pass under our notice. + +The mooted question of determining whether the cattle typhus was +originally imported from abroad, or whether it broke out spontaneously +in England, has been, and still is, a subject of dubious debate amongst +some professional men, amongst the leading writers of the public +journals, and also amongst agriculturists and farmers.[C] + +And, in truth, the propagation of the distemper is occasionally +witnessed under conditions so singular and striking, that it seems to +warrant and supply arguments for every conceivable opinion. + +When the disease was recognised and identified for the first time on the +24th of June, 1865, public opinion ascribed its appearance to contagion +arising from some diseased cows imported from Finland, and which, after +being exposed in the Islington Market on the 19th, were sold and removed +to the cowsheds of a breeder or dairyman. + +We may observe that, on hearing the intelligence of this sudden +invasion, the public mind, which is so excitable in England, did not +disguise the indignation it felt against foreign countries which had +been capable of contaminating an island so advantageously situated and +so well protected, and infecting her magnificent herds, exuberant with +health. But after a closer examination of the facts, and possibly +alarmed, at the serious consequences of a Continental blockade which +would deprive the United Kingdom, not of the entire twenty or thirty +thousand live stock, such as oxen, sheep, pigs, &c., which they receive +every week, but only of the eight or ten thousand head of cattle which +are landed weekly on their coasts to supply their markets, public +opinion was appeased. But, unfortunately, this national susceptibility +now took the opposite extreme; and the only causes it now saw were the +dirt and want of adequate ventilation in the metropolitan stables and +sheds; and to these causes it attributed, first the generation, and then +the propagation or diffusion of the malady; an opinion which appeared +all the more natural and reasonable, in that the oxen and cows of the +graziers were the first victims of the typhus. + +We all know how liable, among all nations, the public mind is to waver +and fluctuate, and how susceptible and open it is to new impressions +during fatal visitations and general calamities; nor can we feel the +least surprise at the uncertainty which has so long prevailed, and still +continues, as to the real causes of the introduction of the bovine +typhus in England. + +Let us therefore examine this question of etiology, and try to discover +what opinion ought to prevail. + +It is important to establish at once two material facts which seem to us +indisputable: + +1st. That the contagious typhus in cattle which is known to be permanent +in the southeast of Europe, actually existed there during the month of +June, 1865; 2nd, That some of the horned cattle, fed and reared in that +part of Europe, were transported to England, after having crossed +through Russia from south to north, in order to avoid passing through +Germany. + +As for the first of these facts, it is admitted and received, as might +easily be proved by reproducing the speeches and addresses delivered by +the veterinary doctors at the Congress now being held at Vienna, and at +which were present the men whose experience of this cattle distemper +gives them the highest authority--Hertwig, Jessen, Röll, Siegmund, +Gerlach, &c. + +The contagious typhus of horned cattle is so fully in the epizootic +state in those countries which are washed by the Black Sea, that it was +enough for the veterinarians present at the Congress to manifest a +desire to see cattle afflicted with this disease, for the opportunity so +to do to be immediately afforded them.[D] + +Thus, then, the fact is undeniable, the contagious typhus was raging, in +June, 1865, in Hungary and Russia, as it rages there at all times. + +As for the conveyance of cattle from those countries into England, the +fact is no less certain and assured. It is well known that a convoy of +300 heads of cattle, proceeding from the pasture-grounds of Hungary and +Austria, was transported into Finland by rail, and afterwards shipped at +Revel for England. Thanks to the rapid locomotion by steam, the +migration of these cattle had lasted but ten days--two days for the +transport by land, and eight days for the passage by sea, through the +tortuous line of the Baltic; but this was sufficient length of time for +the incubation to be produced, even supposing the animals to have looked +sound when their transit began. + +Moreover, it is indubitable that the markets of this immeasurable London +have for many years been supplied with horned cattle from every country: +from France, Holland, Belgium, Podolia, Poland, Prussia, Austria, +Hungary, and Russia. + +Thus, the Islington Market (the fact is assured) had received horned +cattle imported from the countries where typhus is known to be +permanent. Were these cattle thus imported affected with the typhus? +This fact likewise is as certain as the other, since two of the foreign +cows thus imported, were the first to fall sick, and to die of this +typhus. + +But if the contagious typhus of horned cattle rages permanently on the +banks of the streams which discharge themselves into the Black Sea, and +if the beasts reared in those countries have long been transported to +England and other countries, how, it will be asked, is it that the +disease has not broken out more frequently, for it has never been seen +in Great Britain, at least, during the former part of the nineteenth +century? + +This question is not devoid of a certain degree of importance, and +deserves to fix our attention for a moment. + +Now the conditions in which the animals were exhibited in 1863 and 1864 +were precisely the same as those of 1865, before the outbreak of the +disease; and yet the contagion has been possible in 1865, whilst it was +not so in 1863. + +We do not presume to explain the mysterious phenomena which govern the +development of epidemics and epizootics; but it seems to us not +altogether impossible to give a rational and satisfactory elucidation of +the facts. + +In general, in _epizootics_, and I might even say in some particular +epidemics--in that of the typhus, for instance--three connected and +inseparable facts form the condition _sine quâ non_, of the generation +of the disease. First, a focus for producing the virus; secondly, for +the most part a favourable soil, and a special predisposition amongst +animals to receive and propagate it; thirdly, what is called an epidemic +or epizootic genius--that is to say, a particular state of the +atmospheric elements, or the air, which hitherto has escaped our +analyses, and whose morbific properties vary in their degrees of +intensity. Thus the epizootic genius of 1711, the terrible one of 1750, +and the one which now diffuses its contagious miasma, have differed in +some of their virulent conditions. + +However that may be, it will be sufficient to glance back at the past to +assure ourselves that, in general, epizootics have been coincident with +some violent change of season, such as extreme droughts, or +superabundant rains; that is to say, when the cattle, disturbed in the +physiological conditions of their health, have become favourable to the +incubation of the miasmatic leaven scattered through the air, or else +when these animals were living under irregular conditions, and had to +endure unwonted fatigues and privations, as in the folds of campaigning +armies, for instance. + +These epizootics have appeared to depend not only on the state of the +soil and of the health of the cattle, but also (we repeat it designedly) +on an element no less indispensable to the propagation of the disease--a +special state of the air, which favours the development and preservation +of typhic miasma: for sometimes a sudden change of temperature has +proved sufficient to stop the rampant progress of the contagion, the +other conditions remaining unaltered. + +These relations of cause and effect between the contagious principle, +the predisposition of the animals, and the state of the atmosphere, +evidently are subject to some exceptions; but we must allow that in the +present epizootic they are absolutely and completely applicable. For, in +truth, the years 1864 and 1865 have been distinguished, if not by the +persistency of a high rate of temperature not often witnessed, at least +by an excessive drought during the months which are both hot and rainy; +and this has happened in the various countries of Europe, thereby +producing a falling off in the pasture and fodder both as respects their +quantity and quality. + +As to England, a country usually cold and damp, but renowned for its +spacious green fields and meadows, it has suffered more than any other +country from these unfavourable conditions, and their destructive +influence on the grass and corn; the herds having found a great +reduction of food where formerly they met with abundance. Everybody has +seen, as we have ourselves, large herds of cattle, wandering in +amazement from field to field, and seeking for something to browse on a +parched and arid soil. A supplementary provision of corn, roots, malt, +and the grounds of the beer vat or spirit barrel, no doubt served to +mitigate the sad effects of these privations on the health of cattle; +but in spite of all that could be done, their blood became impoverished, +their strength and vital resistance sank, and (like the animals which we +transferred at will into a soil more favourable to the spread of +parasitic diseases), they afforded last June, as they do now, an unusual +predisposition to suffer and transform the morbific principles of +typhus, which in all probability they would have been proof against at +any other time. We may very fairly infer this much, for we must of +necessity believe that the regular importation of cattle from those +countries which are considered as the permanent focus of typhus, has +from time to time transported the miasmatic germs of this malady into +England, although the virus did not take effect on British cattle at +those periods, for want of one or other of the conditions necessary to +its generation and development. + +We may likewise infer, and a watchful appreciation of the facts +contained in the veterinary medical journals would show that this +opinion is not unfounded, that the special disease which constitutes +this typhus (similar in that respect to epidemic diseases), may develop +itself in one beast by accident, spontaneously, sporadically--that is to +say, without immediate contagion; in a word, _apart from those epizootic +conditions which alone render its propagation possible_. To be brief, we +think that an isolated case of cattle typhus may by chance be detected, +when there is no epizootia prevailing to account for it, just as we +occasionally meet with cases of typhus or cholera among men during +seasons absolutely free from these epidemics. It would not, therefore, +appear to us altogether impossible, that under the influence of very +special conditions, the contagious typhus of the ox might have its birth +in England; and this would favour the theory of those reasoners who +maintain that this typhus met with the first causes, and the origin of +its development, in the stalls and cowsheds of London. But such has not +been the cause of cattle typhus in the epizootia which we see at +present. + +No doubt some animals suffered great privations, but, whatever +alteration their health may have sustained, all this is nothing to be +compared to the sufferings endured by the cattle in the steppes under +the influence of deleterious conditions of the most exceptional +character, which do, indeed, give birth to this typhus, and which we +have already described. + +No, certainly not! _Nothing authorizes us to believe that the typhus now +under our observation was bred and born, at first, within the stalls and +cowsheds of London._ It was most assuredly imported. But it is true, +nevertheless, that this cruel scourge found the horned cattle of England +predisposed to receive it, and it likewise met with atmospheric +conditions favourable to its subsequent diffusion; in a word, it met +with the epizootic genius proper for the generation and propagation of +the typhus miasma. + +It is thus that we may account for and reconcile the two contending +theories, one of which refers the cause of this typhus to foreign +importation, whilst the other insists that it originated in the filthy +and half-ventilated cowsheds of the metropolis. + +But if this typhus could not spring up spontaneously out of the bovine +race of England, it must be confessed that, independently of the general +predisposition due to a great and protracted drought, it found in the +sickening sheds of the metropolitan and country cattle the most +favourable conditions for its incubation and subsequent diffusion. + +It would, indeed, be difficult to conceive of anything more directly +adverse to the hygienic laws of health in cattle than the stalls and +sheds dotted over the densely populated districts of London. Most of +these pent-up cribs are situated in narrow lanes and yards, in filthy +streets and blind alleys; and within these close, hot, and steaming +receptacles the miserable cows, pressed against each other, without +ever moving a limb, waste away and become phthisical in a very short +space of time. We may readily imagine what a prey to the contagion must +be afforded by these animals, already more or less ailing, some of which +are fed in a great measure on malt, so sour and acrid that the very +smell of it is intolerable. The milk from these cows is, moreover, of so +wretched a quality, that in a cowhouse containing 48 of these poor +creatures, at Kensington, I found only one, the milk of which exhibited +the taste and quality fit for a sick child, for whom I ordered a milk +diet. + +It is not, therefore, to be wondered at that the present epizootia, +during this late tropical season[E] especially, should have met with all +the conditions most conducive to its development and propagation. + +When the cattle distemper first broke out, the graziers, not suspecting +its gravity, attempted to treat the animals themselves, but soon +afterwards perceiving the fruitlessness of all their remedial measures, +they felt that the best thing they could do was to turn their sick +beasts to whatever account they could, by driving them to market or to +the slaughter-houses, an expedient which they were the more disposed to +adopt, inasmuch as the diseased cows had ceased to give milk. And then, +the removal of these animals, in various stages of the disorder, became +the most rapid means of disseminating the contagion, which, had it been +concentrated and pent-up at first within its narrow focus, would +otherwise have spread with less fearful havoc.[F] + +In the meanwhile the sick cows being commingled with thousands of heads +of cattle exposed for sale at the different markets, communicated far +and wide the principle of the disease; and as a certain number of these +animals remaining unsold were driven back to the farms, into stalls +until then removed from every cause of contagion, they introduced among +their sound companions the fatal germs of the distemper; and as, again, +this effectual means of propagating the evil was repeated several times +in the same week, the consequence was that, by the end of July--a little +more than a month after the outbreak--the whole of the south of England +was in some sort contaminated. Thence the contagion extended to the +north of the kingdom, and passed into Scotland; so that, at present, the +cattle-typhus has spread its ramifications over a great number of the +counties of Great Britain.[G] + +In the first instance, the contagion spread from animal to animal by +means of an infecting influence in some degree direct, among cattle +sheltered beneath the same roof, or collected in swarms within the same +markets. But very soon the air itself was impregnated and polluted by +the vaporization and diffusion of the typhic miasma; and herds of cattle +which had no contact, either direct or indirect, with infected animals, +were seen to be tainted with the distemper. Whether this contamination +was produced by the passage of attainted cattle along the public roads +(having fields on the right and left), or otherwise, nothing but an +absolute isolation, an utter impossibility of contact, appeared to offer +a perfect immunity against the spread of the evil. + +The miasma, condensed by the fogs and transported in all directions by +the winds, now began to overleap every natural or artificial barrier, +and the favoured herds, ruminating at their ease in the manorial farms +of the wealthy patricians, in their well-kept parks and amid every +luxury, were suddenly smitten with an evil which in their case seemed an +anomaly. In such peaceful homes these innocent creatures were tended by +intelligent and benevolent hands, which understood and felt for their +frail constitutions; food of the best quality was lavishly supplied to +them, and whatever they could wish for lay around them in abundance; +richly reared, they had themselves become so many ornaments within these +scenes of beauty, and all men thought that here, at least, were plots of +rural ground which the genius of epizootia would not invade, and in +which the healthy herds were invulnerable to contagion. + +It was under these circumstances that the fine farms of Earl Granville, +at Golder's Green, skirting the Finchley Road,[H] containing as many as +130 milch cows, were suddenly and fiercely attacked amidst their +seeming immunity, and struck down in great numbers. + +"When I left England a month ago," said the noble lord, "there were +about 130 milch cows in four sheds; in the two largest and best managed +I found only one cow yesterday, September 4th." + +The park of Holly Lodge,[I] which is partly bounded by the main road +along which pass and repass files of cattle going to and coming from the +markets, was visited by the same unsparing scourge. Now certainly, the +noble and beneficent lady of the manor, who secured to her cattle every +attention, and who, confiding in the resources of medical science, +attempted every means to save these stricken creatures doomed to an +inevitable death; she whose enlightened mind, equally open to the claims +of science as to those of misfortune, desired that experiments should be +made which might tend to throw any light on this devastating malady; +she, at any rate, one would think, might have escaped the common lot +without exciting wonder or envy at the privilege which she enjoyed. But +this fell and sweeping epizootia, inexorable in its latitudinarian +march, entered those shady bounds, and decimated those orderly sheds +with the same impartiality as it did that of the poor man, Cutting, +whose whole fortune was stored up in the two milch cows whose death he +had to deplore. + +This epizootia threatens to invade, one by one, all the European States, +like the awful scourge of 1750, to which we have already drawn +attention. For even now Holland and Belgium[J] have been smitten; and +the alarm it has excited has for a time superseded the panic which the +stealthy advance of the cholera to the west had kindled. Some imagine +that it might have been kept out of Great Britain, or have been checked +in its outbreak. But, in spite of all the safest precautions and the +soundest measures of preparation, it would most likely have baffled +human skill, and neither been held aloof nor stifled in its focus. But +how painful it is, to have to write and to think that ignorance, +carelessness, revolting cupidity, and the most wanton violation of the +laws, have all contributed to extend the evil, with the foulest +premeditation and the blindest disregard! + +To feel one's self a stranger in a country, and to be able to rejoice at +one's connexions with it, and at the same time to be obliged to give +publicity to certain truths distasteful to those to whom they are told, +is a most painful task. But, as it would be to swerve from that duty and +loyalty which the national interests as well as those of science impose +upon a writer, not to speak out with impartial justice in a matter of so +vital an importance, we beg permission to consider, without reserve, +this delicate question:--the causes which have contributed to propagate +the complaint. + + +V. + +England, so long spared by that wasting scourge, which had so often +extended its ravages over France and other kingdoms during the last +sixty years, was taken by surprise; and the regulations and laws +necessary to stifle without delay the distemper in its focus--that is to +say, in the metropolis--not being in readiness, the outbreak of the +disease found her helpless and unarmed. + +On the other hand, the organic forms of the English Government and +municipal bodies, the reserve of the Cabinet during the vacation, the +limited power of the Lord Mayor and his civic counsellors, the +subdivision of London into parishes and vestries, as in the good times +of the middle ages, the loose scattering of the shambles and meat +markets through the many streets of the huge town, the right asserted by +each man to be absolutely independent and free, the sanctity of the +Englishman's home, &c., &c., all concurred to let loose and propagate +the contagion, instead of keeping it within bounds. + +Indeed, whilst the competent authorities, with all the energy which +could be expected of them on so grave a matter, were meeting and +discussing the best measures to be taken, and the interesting debates at +the Mansion-house were throwing the first light upon the question, the +insidious malady pursued its destructive progress, diffusing new terror +and alarm. When at length the Privy Council issued their orders, +prescribing the public declaration of sick cattle, and that no affected +beast was to be conveyed either by rail or by ship, whilst all the +necessary means of purification and disinfection were to be employed, +&c., it was unfortunately too late, the dreadful calamity having taken +root and multiplied its stem like the upas-tree. + +What a field for reflection there is in these cases, which originating +with the imperfect state of the laws and institutions, have fostered and +encouraged the disease! But this is a subject which it would not behove +us to discuss, and we prefer to show by the notes which will be found +appended to the end of this work, and which are produced as attesting +documents, that cattle proprietors, by their own confession, too often +sacrifice the interests of the public to their own private advantage.[K] + +Nor have we been able to participate in the thoughts and reflections of +so many sensible and judicious persons, on the impotence and +dilatoriness of the public authorities, and also, let us say, on the +inadequate pecuniary means proposed by a people so lavish of its wealth +when useful and great undertakings are designed, without paying a +natural tribute of regret, to the memory of a Prince who took so deep an +interest in the progress of agriculture, and who, had he still been +living, would have known how to direct with a firm and steady hand, the +right measures to be taken amidst so many intricacies and +embarrassments. + +Sometimes allusion has been made to France in the speeches delivered at +these meetings, presided over by that active magistrate, the Lord Mayor. +In the course of these remarks the speakers have praised and held up to +admiration the advantages of her system of centralization, the decrees +of her sanitary police, and the promptness with which she executes the +measures which the public interests require. That is true. France is +certainly in a state to resist the scourge with very effectual means to +arrest its progress; but if in this matter, as in some others, she have +acquired a superiority, it has only been by an experience dearly +purchased, these epizootics having returned more than once to destroy +her flocks and herds. Politically, the same might be said of her +revolutions, those great moral epidemics. + +An orator, a writer, went so far as to say, in one of his numerous +letters, the one dated the 24th of August: "I regret to say some of our +neighbours laugh at our expense."[L] + +No, your neighbours will not laugh at your misfortunes. They sympathize +at present both in your joys and sorrows, and if I have taken up my pen +on this occasion, it has only been because I could not look with +indifference on your too just anxieties, when I flattered myself that I +might write some useful pages to mitigate and relieve them. + +As most newspaper readers are aware,[M] and as everybody may easily +ascertain, the diseased cattle, in spite of reiterated orders to destroy +them immediately, were, nevertheless, driven to the markets to be sold +for what could be got for them; or when their tainted condition was too +glaring they were at once sent off to the private shambles, the owners +of which, in order to disguise the accusatory proof of the misdemeanor, +hastened to sell the body of the animal. It would be quite impossible to +mention all the violations of the law, which every day continue to fill +the columns of the public journals. One graceless wretch, who deserved +to be hanged for it, if his ignorance do not excuse him, was so infamous +as to introduce a sick cow into a shed not yet attainted, in his +criminal desire of propagating the disease there.[N] + +Thus, then, independently of the causes inherent to the typhus itself, +which served of necessity to diffuse it, other causes proceeding from +the defective state of the law, and the perfidy of individuals, have +contributed to its dissemination. And yet the Government circulars, the +newspapers, and the reports of veterinary doctors have made known that +the slightest omissions and inattentions were serious--that the want of +ventilation and cleanliness in the stables, the overcrowding of the +cattle, and their abiding near their own droppings, or dung-heaps--that +the keeping of dead bodies close to farms, cowsheds, enclosed grounds, +and fields--that the hasty and imperfect burial of cattle--that the +collection and transit of their fragments, bones, horns, and skins--that +the driving on the public roads of any animal either tainted itself, or +having lived among those that were sick--that the clothes of persons and +stable utensils, soiled with putrid liquids--that all these, and similar +causes, were capable of propagating or aggravating the disease. + +But whilst we must loudly condemn the voluntary misdeeds of those who +drove their sick cattle to market, it must likewise be allowed that, to +conform one's self rigidly to the given injunctions, was sometimes +attended with serious embarrassments. How great, indeed, must have been +the perplexity of any grazier who, being the owner, for instance, of +forty head of cattle, and having seen ten of them perish under his eyes, +without knowing where to dispose of them, was threatened with the loss +of the remaining thirty within a few days! How could he calmly and +patiently resign himself to suffer so large a quantity of animal matter +to accumulate and putrefy around him, when, suddenly ruined, and +destitute of every resource, the authorities held back instead of coming +to his assistance. + +The prime cause of all the transgressions committed in despite of the +Privy Council's orders, may therefore be referred in part to the want +of compensation to be granted to the owners of infected cattle. It all +might be almost reduced to a question of money. For let us suppose for a +moment, that inspectors entrusted with adequate powers, had been +authorized, after a close examination, to point out the tainted cattle; +to fix a moderate price on them by way of compensation; to have them +slaughtered, carried away, and immediately buried, would not such a +course have diminished the generation of contagious miasma in a +considerable proportion? + +Moreover, some cattle-breeders and farmers exposed themselves to the +imposition of fines and penalties without any evil designs; for when +they drove their beasts to market they were only in the stage of +incubation, at the preliminary period, when it is really no easy task to +distinguish the distemper. The following fact will exemplify this. + +At each market, in spite of continual warnings, the inspectors pick out +and despatch to the slaughter-houses a certain number of sick cattle, +not only those affected with typhus, but with other disorders. One +cannot help wondering, on seeing the poor, lean, sickly condition of +some of these creatures, how their owners could have been so mad as to +expose them for sale; but in their number there are a few which, +although sick, appear in good health to the common observer. + +About a fortnight ago, during one of our visits to the great +Metropolitan Market, Mr. Tegg, the veterinary inspector, whose +intelligence and earnestness are quite equal to the very difficult +charge with which he is entrusted, ordered to be seized and removed to a +secluded fold near the slaughter-houses, a dozen diseased animals. When +once these cattle had been thus collected in a body, it was easy to +submit them to a still closer examination. Most of these beasts, adult +cows and oxen, were lean, panting, feverish, dispirited, and remained +motionless where they stood. But among them was a cow, with a brisk and +lively look, a quick open eye, which watched us with anxiety, and fled +at our approach every time we passed by her. The turn came for this cow +to be examined. Mr. Tegg, strong and handy--as every good veterinary +doctor should be--seized hold of one of her horns, but he was quickly +shaken off; other persons came up to assist him; the fiery animal was +suddenly seized by both horns, by the nostrils, and the tail; but so +strong and spirited was the animal, that she defended herself with +advantage against all her adversaries, and once more shook herself free. + +It was necessary, however, to master the creature, so they surrounded +her again, pressing her back this time into a corner of the pen, to +overpower her. But lo! the animal takes a sudden spring, and leaps over +the bars. Assuredly this cow, for a beast suspected of the typhus taint, +had given a proof, if not of health, at least of extraordinary vigour; +and her owner, who had seen her condemned with much vexation, now +thought he saw ample reason to reclaim her, and drive her back to the +market for sale. However the cow, on taking such a leap, and under +conditions so unfavourable, came down with all her weight upon her +limbs, fracturing one of her forelegs. + +After this accident, we were able to prosecute the examination we +desired, and Mr. Tegg showed us a row of little glandular swellings on +the ridge of the gums, and livid spots on the vaginal mucous membrane, +which confirmed his diagnosis. The owner of this cow, nevertheless, +still discredited the diseased state of the beast; so to convince him, +she was driven off at once to the slaughter-house to be struck down; +but, unfortunately, three or four others filled the required area, so +that the poor cow was forced to witness the execution of her +fellow-creatures before being killed herself. The look and posture of +this cow, her excited yet terrified glance as she surveyed this scene of +carnage, was one of those pictures which no pencil could draw; and +although we acknowledge that man possesses an incontestable right to +apply to his own use the dead or live matter of animals for his food and +sustenance, we could not help feeling for the poor victim, slipping over +the blood, and thus scenting death before receiving the stroke. + +We are not excessively sensitive; we have seen a hundred horses bleeding +from the incisions made by veterinary pupils, and scores of oxen +slaughtered; we ourselves have practised numerous experiments on +animals; but the affecting sight of that animal witnessing the slaughter +of others, and waiting her turn to die, touched us deeply. We could not +help asking ourselves, how it was that man could dispense with +compassion and good feeling even in that bloody toil, and why he did not +bandage the eyes of the doomed creatures he was going to sacrifice? +These dumb animals that we treat like inert matter are sensitive like +ourselves; they are very conscious of pain; and if it be our privilege +to compute the number of our days, we ought not to forget that they are, +like us, endowed with intelligence, so that when they are thus detained +at the place of execution, all their senses and faculties being +concentrated on their destroyer, they are fully conscious of the cruel +fate which awaits them. + +At last it was the poor beast's turn to be slaughtered, and ten minutes +afterwards we opened her entrails, and had proof that Mr. Tegg's +judgment was exact, for already the stomach and intestines offered to +view indubitable signs of the typhus at its first period. + +The owner of the cow was then convinced and brought to reason, but he +still very fairly asserted the goodness of his motives, about which none +present doubted at all, and applied for compensation to the full value +of the beast, both as butcher's meat and offal, which application was +granted. + +Judge, therefore, by this particular example, how many tainted cattle +there must have been which have propagated this distemper, some with and +some without the knowledge of their owners; and, "_horresco referens!_" +how much of this tainted meat must have been purchased and eaten by the +public, since this cow had all the appearance of health and vigour, and +the real diseased condition might not have been detected at all, but for +the experience and sagacity of Mr. Tegg, the inspector. + + +VI. + +In this consideration of the causes of the contagious typhus in bovine +cattle, we have deemed it essential to invite attention both to those +which are generally recognised and admitted, and to those which, though +they may have been settled in the minds of observant and experienced +men, may yet appear hypothetical to certain readers. + +Besides which, in every scientific work, allowance must be made for the +past and future; and here we have two vital distinctions. If the man +who undertakes this task does not go on, he falls back; and it was to +avoid incurring this reproach that we have passed our old boundaries and +visited new avenues. We are aware that more than one objection might be +urged against the opinions and theories which we have exposed, in order +to account for the outbreak of typhus in England; we might anticipate, +we might reply to these objections; but we would rather recapitulate our +inquiry into the causes, in the tangible form of practical propositions. + +From the general considerations above given, we think we may conclude, + +1st. That the causes which generate the cattle typhus on our globe are +permanent and unceasing, not only on the banks of the great rivers which +empty themselves into the Black Sea, but also in other countries--in +America, in Africa, &c.; wherever, in a word, exist the conditions, not +of race (the race of the animal in this case being but secondary), but +of climate and of the organic elements which are indispensable to the +formation and development of typhic miasma. + +2nd. That the cattle typhus, although it exists not necessarily, but +through the improvidence or want of caution in man, on different parts +of the earth, never appears at all in the temperate and more genial +zones, save under particular and special circumstances, analogous in +some degree with those which generate the human typhus--inclemency of +the seasons, overcrowded dwellings, bad or insufficient food, and want +of cleanliness; and that these particular and special circumstances give +birth to the epizootic genus, rendering the cattle fit and apt to +receive the germs of the contagious virus, and to foster its incubation. + +3rd. That the cattle typhus, thus accidentally developed in the +temperate and genial zones, by means of the vicious hygienic conditions +amidst which horned cattle are accustomed to live, and which serve as +the causes of its propagation, is afterwards transmitted by the contact +of animals living in the same stall or shed, or collected in herds on +the same ground, or transported in the same vehicles, by land or sea. + +4th. That the droppings of animals, their litter, their dead bodies, and +their detritus, or broken-up remains--also the stables, vehicles, and +implements which have served for their use, and all matters or +substances which have touched them or approached them--are generative +elements of the distemper. + +5th. That the typhic miasma, thus reproduced and multiplied in one place +under the influence of all these producing causes, is conveyed by the +winds to great distances, smiting those well guarded cattle which +appeared to be fully protected from the possibility of infection by +their isolation. + +6th. That the want of prompt and stringent measures first to +concentrate, and then to stifle this typhus in its focus; the love of +lucre, the perfidy of some, and the absence of foresight and caution in +others, may be, and have been in the particular cases which we are +dealing with, material causes and agencies of its diffusion. + +Such we consider to be the causes which engender and propagate cattle +typhus, and which will serve as a basis for the preventive measures to +be employed in order to withstand and check its propagation. + +FOOTNOTES: + +[B] We are aware that the transport of cattle is conducted in a +different manner during the prevalence of this epizootia. The account +given by two German veterinary surgeons of the management of the vessels +of the North German Lloyd's, and of the manner in which the animals are +treated, is a proof of this; but before the appearance of the epizootia, +the transport of animals by land and by sea left much to be desired. +This account will be found at the end of this work (NOTE A); and all +documents in support of the facts which have served as the basis of our +dissertation, are also in the Appendix, arranged alphabetically in the +form of notes. + +[C] See Notes B, C, D, E. + +[D] See Note F. + +[E] On the 15th of September, the thermometer stood at 80° Fahrenheit. + +[F] See Notes G, J. + +[G] See Notes K, L. + +[H] See Note M. + +[I] See Note N. + +[J] See Notes O, P. + +[K] See Notes R, S, T. + +[L] See Note V. + +[M] See Note Y. + +[N] See Note Z. + + + + +CHAPTER III. + +_Description of the Contagious Typhus of the Ox; its Symptoms, Course, +Progress, &c._ + + +I have already written the history of the typhus which affects the ox; I +have shown and dwelt upon the signs and characters of typhus diseases +generally, deducing therefrom the denomination and definition of that of +the ox in particular; finally, I have described the causes which +generate and diffuse it abroad. + +Now, I must make known the various phases and alterations to which the +disease is liable, and which, in the language of the medical schools, +are called its symptoms and characteristics; its progress or course; its +prognosis; its _post-mortem_ appearances, &c. &c. + +This examination, like those which have preceded it, will afford new +foundations for medical practice. + + +I. + +_Symptomatic Characteristics._--The typhus of the ox, like all +infectious and contagious diseases, offers to observation four +successive changes: 1st, a _period of Incubation_, during which the +original structure is subject to internal and latent derangements; 2nd, +a _period of Initiation_, during which the first evident signs of the +disease are manifested; 3rd, a _period of Endurance_, during which the +phenomena are fully developed; 4th, a _period of Decline_, or wasting +atony. + +These divisions and classifications, it will readily be conceived, are +rather fanciful, for nature does not adapt herself to our methodical +forms. Still we shall abide by them, because they have their relative +and practical utility, and because they will afford to the practitioner +suggestions more easily understood; and finally, because the organic +changes are different at these various periods, which in their entirety +constitute the typhus of the bovine species. + +The description of those different phases through which the organism of +cattle smitten with the contagion has to pass, has moreover been given +in a masterly manner by the veterinary physicians of the different +European countries, especially by those in which opportunities to +observe it have been most frequent--that is to say, by the Russian, +German, and French veterinary doctors, Jessen, Röll, D'Arboval, Gellé. + +The English physicians of the 18th century, as we have already seen, +were also in no respect inferior to those of our own time. Finally, Mr. +Simonds, who published a very able Report on his return from his +scientific exploration in Galicia, in 1857, and the skilful Professor +Bouley, in his recent communications to the Académie de Médecine, in +Paris, respecting his examination of the present cattle typhus in +England, have described the disease with minute exactness, as we +ourselves have verified on the various sick beasts which we have seen +during the last two months. + +1. _Period of Incubation._--Several careful experiments, which have been +cited in the historical division of this work, and numerous fortuitous +occasions, have authorized us to assign a duration of nine or twelve +days to the period of incubation, according to the general conditions +of the epizootia, the manner in which the contagion is transmitted, and +the former state of health of the affected cattle. + +Thus an epizootia at the outset, either when it has become general, or +when it is at its decline, does not always transmit typhic miasma of the +same virulent intensity, nor does it always provoke in the frame a +labour of incubation which is invariable. The contagion transmitted from +animal to animal living continually in the same stalls or sheds is +followed by an incubation more quick and active than that which results +from a chance contact in the markets, or from a contagion produced at a +distance, by the transmission of the miasmatic effluvium along the +public highways. + +Let us add to these considerations the relative state of each animal's +health, and we shall then perfectly understand that the incubation must +vary both in its continuance and in the characteristics of its +manifestation. In some animals it scarcely betrays the derangements +produced by its morbid operation: they preserve their appetite and their +usual looks. A close and attentive observation would alone be able to +distinguish some slight alterations in their way of living, in the +regularity of their rumination and sleep. But in others, there is no +mistaking a something irregular and unusual in their appearance and +living; the vital state is no longer the same. Thus an animal which used +to be cheerful and familiar becomes silent and solitary; it browses the +grass with less eagerness and avidity; it lies down more frequently and +longer; it lingers by the side of the hedge along the field, or it +wanders about, here and there, with a listless look, and without any +object. Others moan and complain, bellowing at intervals in an unusual +manner, very expressive of languor and pain. + +But apart from seasons of epizootia, the beasts too often exhibit these +imperceptible shades of variety in their looks and actions for the +attention to be struck by them; these changes, therefore, are almost +always unnoticed. + +However, the typhic miasma absorbed at the same time by the respiratory +and digestive mucous membranes serves to modify the qualities of the +blood, and secretly reacts on the nervous system; soon after, the +animal exhibits more decidedly those changes which previously were +hardly to be detected; his want of appetite is more marked, his sadness +more obvious, and his attention fixes itself more slowly and carelessly +on the objects which surround him. When he is in the shed, his usual +food is found in excess of his wants, his thirst is much keener and more +frequent, and a continual dejection and lowness of spirits or a +transitory agitation disturb all his functions. When the farmers or +graziers notice these premonitory signs for the first time they pay but +little attention thereto; but if the contagion has found its way into +their stalls and sheds they are no longer deceived by them, but begin to +apprehend that in a day or two fresh victims will be added to the +number. + +2. _Period of Initiation._--Soon the elaboration of the virulent miasma +in the organic structure changes the quality of the blood and humours, +the functions of assimilation and secretion are modified, the nervous +centres receive vitiated organic elements and are disturbed in their +physiological conditions, and the smitten animal displays that state of +latent uneasiness which he is imperfectly conscious of by a general +look of heaviness and stupor (Τυφος), which has suggested for this +disease its name of typhus. + +Indeed, the poor animal's eyes are fixed, the hearing becomes obtuse or +indifferent, as may be seen in the sinking of the ears, those organs +which are so sensitive, so contractile, and so vigilant in herbivorous +animals. With the head hanging down and motionless, the neck stretched +out, their forelegs open and spread, their buttocks drawn together and +one of them completely lax, they seem to succumb beneath the weight of +their bodies. In a word, the animal exhibits through its whole bearing a +heavy sadness, a general dejection, which bespeak a great derangement in +the whole structure. From this time, in the animals which are most +seriously affected, the appetite ceases, the rumination becomes +irregular and partial, whilst in some others the appetite and rumination +are maintained in different degrees. + +But the incubation of the morbid elements pursues its course, the +alteration of the blood becomes general, and the circulation is +increased and quickened. After this the fever interposes and stops the +secretions, that of the udders is dried up, the mucous channels cease to +flow, the mucous membrane of the mouth becomes whitish, the little +glands situated on it are more permanent, especially in the +circumference of the gums; the floor of the tongue and the larynx are +inflamed, the mucous membrane of the cow's sexual organs is red and +furrowed with livid streaks, the white of the eye is parched, and the +skin feels alternately hot and cold, as well as the horns and hoofs. + +Some of the sufferers have an external horripilation, transient +shiverings are felt in the front and hind quarters and at the junction +of the limbs with the trunk. Some pregnant cows near their delivery +miscarry. In a word, at this period of irritation, the whole frame is at +war with the typhic elements which besiege it, and which overcome the +preservative power of the vital forces, and from this general +disturbance arises an incandescent fever, which drains and stops all the +secretions at their source. + +These general symptoms are the first signs and warnings of functional +derangements more significant, which may, however, vary according to the +predispositions of each animal, and transfer their evolutions either to +the nervous centres or to the respiratory mucous membrane, or to that of +the digestive channels, in the inflammatory and febrile form of the +contagious typhus. Such at least is what we observe in the typhus of +1865 in England. + +The functional derangements, in truth, subordinate to and depending on +the predispositions exhibited by the cattle, are far from being the same +in all. In some, the nervous derangements predominate; in others, it is +those of the respiratory, and in others, it is those of the digestive +channels. + +As in this period of irritation the nervous centres are more +particularly affected, the animal suffers cerebral and rickety pains, a +constant cephalalgia, which provokes vague anxiety; he is sometimes +cheerful, sometimes wild and furious; he clenches his teeth and yawns, +the muscles of his face spasmodically contract, the spine feels very +sensitive when pressed, a burning and insatiable thirst comes on, the +breathing is hurried, and the intestinal evacuations are suspended. + +In this form the toxæmia appears to concentrate about the nervous +centres--as is observed elsewhere at the outset of certain violent +fevers, in the typhus and typhoid fever of man, for instance--and some +of their number may perish the victims of these nervous disorders, and +even fall as if struck with electricity. They die apparently from the +result of the typhic poison; for at this second period, we do not trace +in the nervous centres those injuries which might account for so sudden +a death. + +When the respiratory apparatus concentrates upon it the febrile +congestion, the breathing becomes painful, accelerated, embarrassed, +sometimes convulsive, and a deep, oppressive cough is heard from time to +time. The animal, under the yoke of this oppressive uneasiness, turns +his head from right to left, scents, and seems to question his flanks, +where the seat of the disorder is; and then, whether the pulmonary +affection is congestive or inflammatory or emphysematous, he may die of +the consequences of obstruction to the pulmonary circulation and from +the alteration of the blood, under the influence of a slow asphyxia, +but only at the third or fourth period. + +Finally, when the typhus localizes more particularly its morbid +phenomena on the digestive channels, we discern local alterations on the +floor of the tongue and the buccal mucous membrane, spots of livid red, +leaving behind them ulcerations of greater or less extent and depth on +different parts of the intestinal canal. In this form, which follows +more regularly all the periods, constipation is obstinate at the outset, +evacuation of the bowels takes place with difficulty, the fæces are hard +and the urine scanty, the belly is inflated and sensitive. + +Sometimes at this period of initiation, one of these three symptomatic +forms--the nervous, the pulmonary, and the digestive--may predominate +exclusively, so far as to mask the disease as a whole, and to constitute +it a special malady. But in that case, it is only the exaggeration of +the functional derangements which in their total constitute the typhus: +for when the distemper pursues its course, these three principal centres +of life are always affected in different degrees. Thus, not one of the +cattle smitten with the typhus goes through all the phases of the +disease, without suffering at a given moment in its nervous, +respiratory, and digestive functions. + +In this respect, the typhus of the ox presents an apparent analogy with +the typhoid fever in man, although it is different. Consequently, the +name of _typhus fever_ given by some veterinary surgeons, is not +altogether inapplicable to it. + +3. _Period of Duration._--At this stage of the disease, which may be +said to extend from the fourth to the seventh day, the nervous +derangements are confined to symptoms of uneasiness and sensibility +along the dorsal spine; for those cases which exhibited more violent +derangement in the nervous functions have proved fatal. In this period +of the disease the breathing is more embarrassed, particularly when the +pulmonary form of the disease prevails. The pulse, which is hard and +frequent, indicates from forty to sixty pulsations; the beatings of the +heart are more violent and audible; the mucous membranes, dry at the +outbreak, recover their secretions, but these latter are endowed with +irritating properties. Thus the eyelids, swollen and tumefied at the +edges beneath the lashes, drip with a corrosive liquid, which soon marks +its furrow along the chanfrin; the bronchiæ, the trachea, the nostrils, +the salivary glands, exude a serosity which runs out of the nasal and +buccal orifices. The exanthematic eruption having discharged itself +through the digestive channels, constipation is followed by diarrhoea, +rumination is completely stopped, the beast declines all solid +nutriment, and pants for drinks,--for those especially which have a +slight taste of acidity in them. + +The derangements at this period pursue a rapid course--the breathing +becomes more and more difficult, the skin is hot and dry, the hairs +stiffen more and more, gases are developed in the cellular tissues +beneath the skin, along the dorsal vertebræ, at the abdominal folds of +the posterior limbs and under the abdomen, in the form of flat, uneven, +crepitant tumours, which crackle when pressed with the hand; the +diarrhoea becomes more liquefied and irritant, for then it is no +longer a flow of droppings covered with mucus which is expelled, but +secretions already putrid, sometimes reddish in colour, and attended +with foetid gases, which induce tenesmus in the rectum, and force up +the tail. The animal grows perceptibly lean, his dejection is extreme, +and cows which are with calf miscarry. + +At night, the animal seems to have an increase of fever, sometimes of a +remittent type, after which he becomes drowsy and lies down to rest +himself or to sleep, if he can; but the difficulty of breathing, the +abdominal pains, soon force him to rise again, which he cannot do +without an effort. + +4. _Period of Decline and Sinking._--This stage is observed to extend +from the eighth day to the twelfth or the fourteenth. The morbid +functions pursue their course, for the disease has its regular phases +and a successive variation of phenomena. The secretions, which a few +days before were fluid and irritating, have undergone a change; they +have become thick and purulent, they flow more slowly from the ocular +mucous membranes, and also from the nasal and buccal, which are red and +inflamed, and they already emit a foetid smell. The dull tarnished +eyes become hollowed, purulent mucus lodges within their orbits, the +bronchiæ are stopped up, the breathing grows louder and more panting, +the animal instinctively stretches his neck to ease it; the wasting of +the flesh exposes the bones of the sacrum and coccyx, laying bare the +vertebræ and the ribs; the emphysematous tumours are more extensive and +crackling; the skin, less heated, wrinkles up and splits about the bony +protuberances; the udders are crusty and excoriated; detached boils, +hard and rounded at first, then soft and purulent, begin to show +themselves on the trunk and the upper parts of the limbs. The +diarrhoea, still frequent, becomes bloody and intolerably offensive. + +At this final period the organic structure yields to the effects of a +general alteration of the liquids and solids. The vital force has lost +the power of reaction; a mass of blood, decomposed by the double +influence of a virulent toxæmia and the obstructions of respiration, +conveys to all the organs a principle of dissolution; the nervous system +is in a manner paralysed, as is shown in the animal's insensibility. + +The secretions stop up the various channels and cavities; they lodge +within them; they undergo a putrid decomposition, and pass out with +difficulty in the form of a purulent and bloody flux, in the highest +degree infectious. Very soon the sick animal has ceased really to live; +it struggles and labours with its agony; if the lungs are clogged with +gas or fluid they rattle hurriedly and often; the animal cannot hold its +head up even when lying down, and when standing moves it to and fro as +if affected with the natural shaking of old age, and as if seeking to +ward off some indescribable evil, the occurrence of which it was +awaiting. + +The animal's body is a prey given up beforehand to the laws of organic +decomposition: the internal mucous membrane of the cheeks and lips peels +off in strips when rubbed; the sores on the skin have a livid and +gangrenous look; the eggs which the flies deposit on the edge of the +eyelids and at the nasal orifices, or on the excoriations of the skin, +quickly pass into the state of larvæ. The air they expire is cold and +infectious; the native caloric, extinguished in every focus +successively, disappears; the vaginal mucous membrane is tumefied, the +anal opening gapes, and from it flows a bloody and decomposed liquid +which the rectum can no longer expel. The mouth, half open and coated +with a thick glutinous foam, vainly tries to inhale long draughts of air +which can no longer reach the lungs. Finally, if the animal is lying +down, he expires in slow agony, his head borne down by its own weight; +or, if standing, he sinks and falls down, his death having anticipated +the fall. + +Such are the symptoms--the subjective signs which enable us to detect +the contagious typhus of the ox. But all animals do not exhibit these +disorders of the vital functions with the same regularity and excess. +Some of these we have seen, from first to last, sustain the internal +effects of the morbid process--in some sort passively--without revealing +any deep derangements in the nervous, respiratory, and digestive +functions. The poisonous virus had smitten them; they suffered in their +general structure; they looked stupefied; they lost, at a given moment, +their appetite and rumination; they had fever; their breathing had +become short and frequent; they had diarrhoea; they gradually lost +flesh, and the excreta passed through certain changes and +transformations. In a word, the animal had manifestly the bovine typhus; +but, thanks to a relative immunity, to a special organization, which +renders some of these beasts capable of resisting the contagion for a +long period, and sometimes altogether[O]--thanks to that variety which +we observe in different constitutions (for small-pox and typhus in man, +and the true typhoid fever in animals, do not operate with the same +violence on all alike)--thanks to this privileged organization,--we have +seen some oxen pass through every stage of the disease without +exhibiting this terrible train of morbid phenomena. + +In these cases--for even this mild form of the distemper at last +produces death--the injuries fix themselves more exclusively on the +digestive channels, and we witness, in dissection, ulcerations in some, +in others mere spots of a livid red, more or less extensive. + +Finally, although the typhus be one of the gravest maladies which +destroy and decimate cattle, all sick animals are not mortally affected +thereby. In the present epizootia, five per cent., as nearly as can be +ascertained, recover; and when that happens, signs of a favourable omen +are observable during the course of the attack. In these favourable +instances, indeed, the symptoms, even though they exhibit a certain +gravity, pursue a regular course; fever does not become remittent; the +fæcal discharge is copious and easy, with less foetor; the animal +loses flesh slowly and progressively; the tumours are cutaneous, +inflammatory; their character is good, depurative, and rather purulent +than gaseous and crackling. The droppings do not show that high degree +of pestilential decomposition described above; the animal in his drink +welcomes and digests a mixture of bran and flour; the secretions of +purulent mucus and the fæcal discharges dry up and stop in the early +part of the period of decline; the epidermis of the openings through +which they passed out peels off in thin scales, and afterwards in scurfs +or husks--in a word, the economy does not experience those acute +disturbances which strike one of the tripods of life--that is to say, +either the nervous centres, the lungs, or the digestive organs. + +Now, in these curable cases, in which the cure is most generally due to +nature's own efforts, but which a systematic treatment might render far +more frequent, the convalescence is long, and requires great attention +and a well-regulated diet, in which the food is carefully measured and +divided. Here there must be a rigid superintendence. A laxity in the +watchfulness, or too much reliance on the reviving health, have produced +sudden relapses, and been fatal to many sick cattle, which had been +looked upon as thoroughly cured. For it may well be conceived that +convalescent animals, after sustaining such violent derangements in +their health, and having been brought down to the lowest degree of +prostration and marasmus--to a reconstitution, we may call it, of the +solids and liquids--have a devouring hunger. If, therefore, the keeper +who looks after them unhappily forgets that the principal lesions or +sores are seated in the stomach and intestines, and if he gives them too +much solid nutriment, he impedes the cure, irritates the ulcerations not +yet thoroughly covered over, and soon adds another victim to those which +had already died. + +This convalescence lasts from fifteen to twenty days, and the animal +only recovers its health at last by slow degrees. Still the careful +keeper need not be afraid of a relapse when he is patient and watchful. + +Such, then, is the contagious typhus of the ox. Type of the unreturnable +infectious diseases, its virulent miasms undergo within the structure a +series of transformations: they produce in the frame a general disorder +fully capable of annihilating the predisposition or aptitude of the +animal to receive the taint. A disease essentially specific, it affects +the principal centres of life; it kills its victim both by its deadly +virus and by the local derangements to which it gives rise; for how is +it possible to preserve life when the whole nervous system, that +promoter and regulator of all the functions, is upset?--when the lungs +which revivify the blood, when the digestive organs which are the very +sources of alimentation, are smitten with stagnation?--when, in fine, +not only these vital centres have ceased to operate, but when each by +itself is the cause of torturing pains and exhaustion? + +The typhus, moreover, is observed in all animals of the bovine species, +whatever may be their race, their age, or their sex. The recovered +animals may live with impunity amidst diseased herds of cattle, thanks +to its non-relapsive nature. Jessen has even witnessed cows which, after +their own cure, communicated a sort of immunity to their offspring. For +the same reason it is that epizootias are less fatal in those countries +where they often occur, the constitutions of those animals which are +engendered amongst such habituated herds, preserving a prophylaxy +inherent to the blood which has been transmitted to them. + +Besides, what a pregnant subject is this for the physician, and what +more meritorious task can he set himself than the treatment of such a +distemper, which reason assures him must eventually lead to the cure and +eradication of the same complaint in the human species? + +From a cause which as yet has been indistinguishable and imponderable, +what important, what marvellous results loom in the future! The air +seems to us pure and wholesome, yet it conceals a typhic miasma of the +most deadly kind; it carries this pernicious principle into the richest +meadows, where we see feeding flocks and herds which to us seem +exuberant with health. Then this miasma is inhaled and absorbed, and it +meets in the frame the special and indispensable organic element which +is needed for its multiplication; there it undergoes certain latent +transformations, and a fermentation, a germination, which we call +_incubation_, in order to explain a process which we cannot understand. +Then fever is kindled, all the functions are disturbed, and the sick +animal is struck down, leaving us wondering, ignorant, and powerless +spectators in the presence of phenomena which, nevertheless, are the +eternal work of nature and have endured through all time.--But if in +the invisible typhic atom nature gives us death, it also gives us life +in the zoosperma. + + +II. + +_Lesions found in the Bodies of Oxen after Death._ + +The description which we have given of the disorders produced in the +different functions by the operation of the typhus, may easily suggest +what must be the lesions exhibited by the organs of the body. + +Death, we have said already, may overtake the disease at any of its +periods, and thus show every aspect and every degree of the organic +lesions. Such an animal being struck down at the period of initiation, +will not, of course, present the changes and varieties of the period of +decline, and _vice versâ_. + +In general, the state of the dead bodies is that of the most decided +marasmus; the remains are intensely repulsive, as well by the stench +they emit as by the sight they afford; and, in summer especially, +decomposition sets in with great rapidity. Consequently, the utmost care +is required in conveying them from place to place; and this attention +is the more essential, because in the transit, the cavities being +deprived of their contractile power, let flow the pestilential liquids +which they contain, thereby infecting the carriages and public roads. +The urgent necessity there is to inhume at once these dead bodies, the +most active agents in diffusing the contagion, is equally the drift of +this observation. + +The deceased animal, as a subject of anatomy, enables us to certify the +seat of the emphysematous tumours, and to see that they are really due +to the air which insinuates itself into the cellular tissue, and which, +receding from the pressure of the fingers between the cells, produced +the crackling sound we noticed above. This penetration of the air is, +moreover, a far more general effect than was supposed. + +It is ascertained, likewise, from the examination of these subjects, +that the round, fluctuating, and smaller tumours, are indeed purulent +gatherings, which occasionally find a passage into the layers and +interstices of the muscles. + +The muscular flesh is usually flabby, bloodless, unsightly, of a very +nauseous smell; and it would be difficult to imagine that the most +avaricious trickster would dare to offer even the most presentable parts +of it for sale and consumption. But when the expedients and artifices +known to the butcher's trade are had resort to, when, regardless of the +public health, the unprincipled dealer selects the most fleshy parts, +when he dresses and adorns them by colouring them over with the blood of +a healthy beast, the unwary eye of the purchaser may be deceived. +Observe, that we are now speaking of cattle that have died in the last +stage of this marasmus, so that we might suppose, even if the many +summonses before the magistrates, and the too moderate fines which have +been imposed on the guilty parties, had not shed the broadest light upon +the fact, that _a large number of sick cattle which had been slaughtered +at different stages of this frightful disease, have been dressed and +adorned, exposed for sale, sold, and eaten by a very large portion of +the inhabitants of London and of the country likewise_. + +_Digestive Channels._--The mucous membrane of the buccal cavity is, for +the most part, of a livid whiteness; ecchymosed stains, and sometimes +ulcerations, differing in their form and number, are visible on the +floor of the tongue. Mr. Simonds has had an anatomical model +constructed, which presents a perfect type of these ulcerations, some of +which are of a scarlet hue, with perpendicular edges. The _stomachs_ +exhibit a variety of ulcerations. + +The _paunch_, or first stomach, always contains a large quantity of food +intended for rumination; sometimes these aliments are dry, and lie +sticking to its sides; at other times they are diluted with water which +had not yet been absorbed after drinking. The inner membrane of this +first reservoir may show flat spots, with livid injections of different +sizes. + +The _honeycomb_, or second stomach, generally exhibits the same injuries +as the paunch. + +The _manyplies_, or third stomach, contains between its laminæ hard, +pulverulent, and dry alimentary substances, which are seen sticking to +the different leaves. On removing these substances, some ecchymosed +spots are laid bare, the epithelium of which easily peels off; +sometimes ulcerations, and even perforations, are visible. + +The _reed_, or fourth stomach, whose sides are thicker, more fleshy, and +more vascular, exhibits within its folds various kinds of lesions or +sores: they consist of large flat stains of a darkish red, more or less +soft, and sometimes ulcerations red on their deep surface, with clean +edges. + +As for the intestines, properly so called, the _duodenum_ shows the same +injuries, but most generally large ecchymosed spots. + +The _small intestine_ appears on the outside, even when it preserves its +place in the abdomen, of a reddish colour, lined with vessels distended +with blood, the signs of a general congestion of its membranes. The +examination of the mucous membrane, after it has been cut open +lengthways, shows, indeed, that this portion of the digestive tube is +the principal seat of the distemper; for, independently of this general +injection, you perceive ulcerations which have succeeded to detached +pustules or lengthy flat spots, the result of a cluster of several of +Peyer's glands, brought together by the plastic influence of +inflammation. These flat spots, or wafers, very similar to those we +observe in the typhoid fever of man, are inflamed and ulcerated in +different degrees. + +The mucous membrane of the _large intestine_ exhibits lesions depending +on the period of the disease. About the third period, the injection is +sometimes general, especially near the rectum; but in the fourth and +last period we often meet with ulcerations which are smaller in the +upper part, larger and deeper about the lower or rectal part. The +membrane of the sexual parts of the cow is strongly injected, and of a +dull red colour. + +As we have seen, the different organs of the digestive apparatus may, in +this typhus, offer to view extensive alterations perfectly consistent +with the gravity of the symptoms or the functional derangements. In two +cases in which disorders of the respiration had prevailed, and which had +been sacrificed on the eighth or tenth day of the disease, we only +observed partial injections of a very limited character, either on the +gastric membranes or on that of the intestine, and which might have +been detected in the case of common intestinal inflammation. Therefore, +in these two cases, the characteristic lesions of the typhus, if they +must be localized in the intestine, were, so to speak, absolutely +wanting. It was, we will not say exactly the same, on four other +animals, three oxen and one cow; but if, in two of them, the fourth +stomach was inflamed, if in the third the small intestine was congested, +and if, lastly, in the cow the large intestine showed ulcerations, we +could not in these lesions distinguish those of typhoid fever. + +These facts struck us with great surprise, for we were far from +suspecting them. We hoped, on opening the intestine of these animals, +which had certainly all died of the typhus, to meet assuredly in a +determined spot some well-known lesion declared beforehand. To our great +astonishment, such has not always been the case. So that our theories, +conclusive as they seemed on the identity of the ox typhus and the +typhoid fever in man, and which more than anyone else we wished to see +confirmed, must submit to observation. + +In fine, in this epizootia the intestinal lesions or sores present +different appearances. Developed to the utmost in some cases, so much so +as to exhibit ulcerations at the root of the tongue as well as in the +intestines, and to be in a manner the excess of the injuries which are +seen in typhoid fever, they are in other cases scarcely perceptible, and +sometimes entirely absent, when the animal is struck down in the third +or fourth period, that is to say, when the exanthematic or pustular +state has had time to develope itself on the digestive channels. One of +these animals seized by Mr. Tegg at the Camden Town market, was in such +a state of exhaustion that he could not be driven to the +slaughter-house, only two hundred yards distant; they were forced to +fell him on the spot midway, in order to have him conveyed to the place +of dissection. We only detected partial injections on the digestive tube +of this beast. The pulmonary emphysema which had caused this animal's +death was developed in the highest degree.--He was opened at the request +of M. Bouley, of Alfort. + +_Apparatus of Respiration._--Here, again, the typhus shows us injuries +which differ from those of typhoid fever; for if the breathing is always +more or less obstructed at the outbreak of this fever, no serious +organic change in the lungs is the consequence thereof. In the ox +typhus, on the contrary, when the pulmonary form prevails, the +derangements of the respiratory organs are remarkable. Thus, the mucous +membrane of the nostrils, from which flows a purulent and fetid mucus, +is sometimes ulcerated and excoriated. The larynx and the trachea or +windpipe, choked up with frothy mucus, show the same alterations, though +less frequently. The lungs, which are rather congested than inflamed, +are emphysematous, the air having entered and distended the cellular +tissue which unites the lobes together. + +In some cases, the lungs are so gorged with air that their lobes +constitute but a single heap, rendering them irrecognisable, so greatly +do their volume, their specific gravity, and their spongy aeriform +aspect differ from the natural state. + +_Apparatus of Circulation._--The inner sides of the heart show +ecchymosed spots, and the same is the case with the larger vessels. The +blood, diminished in its quantity and altered in its quality, is +blackish and more fluid; but in most cases it coagulates instantaneously +and in a mass, without separating into its solid and liquid parts. + +_Nervous System._--Having observed and dissected the dead bodies at the +slaughter-houses of the markets, we were not able to examine either the +brain or the spinal marrow. Besides, let us remark in this place, that +the mode of felling cattle in England would have rendered impossible +such an examination. For the animals are struck with a club, which kills +them both by cerebral concussion and by the direct alteration of the +brain; the instrument having a sharp end which perforates the skull and +injures the cerebral lobes. Nor is this all; the moment the animal is +struck down, a flexible rod is inserted into the hole made in the skull, +and driven as far as the spinal canal, so as to tear to pieces the +protuberance and the bulb, that is to say, the vital knot. This manner +of killing cattle seems to us, however, preferable to the one adopted +in France, where the animal does not sink till he has been struck +repeatedly with the club. + +But be that as it may, those authors who have examined the nervous +centres of horned cattle which had perished victims of the typhus, have +usually found the meninges, or membranes that envelope the brain, +injected, whilst the brain itself was slightly dotted over with blood. + +These anatomical lesions of the nervous centres being insufficient of +themselves to explain the death at the second period, we have +endeavoured to give the explanation of it in treating of the symptoms. + +The other organs, the spleen, the liver, the kidneys, present +alterations of a secondary interest only. + + +III. + + _Diagnosis--Prognosis--Use of the Flesh of Animals which have + Died of the Typhus--Danger of direct Absorption._ + +The typhus of the ox has such distinct and strongly marked +characteristics that it is not easily mistaken. However, to conform +ourselves to received custom, I will say some words about the principal +symptoms of some distempers affecting the ox, between which and typhus +unprofessional persons might be embarrassed, and hesitate to distinguish +them. We will transfer, however, those particulars pertaining to the +diagnosis to the part written for the special use of agriculturists, +farmers, and graziers, in order that they may readily find whatever it +may be necessary for them to know when they chance to have any sick and +tainted cattle to treat and cure. + +We have likewise a few words to say on the subject of the prognosis of +the disease, as regards its propagation and its time of lasting. +Finally, we will unfold a question of very real importance in +hygiene--we mean the use and consumption of the flesh of animals as +food, and the danger which may accrue to man and other animals from +contact with their dead bodies, or fragments of the same. + +The diseases of the ox, which we are accustomed to consider as +distinguished from typhus, are the contagious peripneumonia, the +apthous fever, and the "charbonneux" typhus; but, as we have just said, +we will mention by-and-by their chief characteristics. + +Everyone is anxious, and natural indeed is that anxiety, to know what +this epizootia will become--what will be its course; how long it will +last; whether it will extend its ravages over the whole extent of the +three kingdoms; and if, in fine, it will invade all Europe. + +To answer in a precise manner these questions would be a difficult task; +for who amongst us can assign at present any definite course to the +atmospheric variations? and yet they have a genuine influence on the +progress of the epizootia. On the other hand, the measures which have +been taken hitherto to confine the contagion to its different foci, have +unhappily proved almost ineffectual, but it may be hoped that, assisted +by experience, we shall be able to resist the evil more effectually, and +check its propagation. + +If the atmospheric conditions and the preventive measures could not +modify the spread of the distemper, we should have reason to dread a +still greater extension of the contagion; for the virulent character of +the epizootia appears to be of an exceptional intensity, and we may +perhaps compare it with the famous epizootia, of the middle of the +eighteenth century, which for ten years afflicted all Europe with its +ravages, striking down six millions of horned cattle. + +Let the reader cast an eye over the extracts borrowed from the +physicians of the principal faculties who have described this typhus, +and which we have reproduced in the first part of this book relating to +its history, and he will then be convinced that the disease is +absolutely the same as that which then raged so fiercely. And if that is +the case, we must anticipate that it will extend its ravages whilst +prolonging its duration. Already it has spread to Holland and Belgium; +Hungary and other provinces in the south-east of Germany--a fact much +less surprising--are likewise smitten with it; and now we hear the news +that France, though so vigilantly on her guard, has seen her frontiers +passed over. In spite of the _cordon sanitaire_ which she had prudently +established everywhere, some horned cattle have been seized with the +typhus at the town of Raubaix, in the north. + +Without setting ourselves up as pessimists, let us declare that we must +expect that the contagion will continue to spread. Let us make up our +minds to this, in order to take the necessary sanitary measures, and set +ourselves seriously to work by trying the preventive treatment. But, +alas! between the Government, the municipal corporations, the +agricultural societies, the cattle proprietors, and, with regret we add, +the veterinary surgeons, there has been sadly wanting, up to the present +time, that mutual understanding; that prompt and decisive action, and +those pecuniary advances which are so necessary to encounter and contend +with this great calamity. + +As for estimating with any approach to accuracy the sacrifice of +property; the pecuniary loss, which this fatal epizootic may occasion +the country, the want of exact statistics as to the number of cattle +which have already been struck down will not permit us to do it. But we +may, perhaps, already set it down approximately from 50,000 to 60,000 +head of cattle for England and Scotland, until we have obtained more +precise statistical information on this significant point of inquiry. + +That would represent, however, a very considerable capital; for if we +compute the loss of each animal at the average sum of 15_l._ only, the +sacrifice already incurred would not be less than from 750,000_l._ to +900,000_l._ This sacrifice in money might possibly have proved the be +all and the end all; and at this point we might, perhaps, have arrested +the contagion, had we all been able to act advisedly and harmoniously +together, in the name and for the interest of the public, from the first +appearance of the disease. But this calculation of, let us say, +900,000_l._, is made on the supposition that each cattle owner had been +willing to abide by his own loss; whereas, unfortunately, many of them +have striven to shift it on others, and large numbers of the sick and +tainted beasts having been sold and consumed, a proportionate sum thus +recovered by those avaricious men must be of course _deducted_ from this +estimate. Deducted, indeed! Considering the consequences on the public +health, is it not rather an aggravation than a mitigation of the loss? + +These last assertions naturally lead us to inquire whether we are not +justified in saying that the flesh of sick and tainted cattle, thus +circulated and consumed, has not had its baleful effects on the public +health. + +The butchers who sold the flesh of these sick and tainted cattle have no +doubt been careful to abstain from using it in their own families; and +the first time they speculated on the health of their fellow-citizens, +well knowing what they did, their conscience probably reproached them +with the misdemeanour. But afterwards, when no bad consequences to their +customers had been seen, their own impunity, joined to this apparent +harmlessness to their neighbours, rendered them bolder, and it became a +daily habit with them to sell this peccant offal, which poisons even the +earth by its contact. + +Moreover, the graziers themselves were in league with the butchers, and +took care to slaughter the affected animals before the wasting of their +flesh by the progress of the distemper had bereft them of their greatest +value. Their private interest prompting them thus to dispose of the +sick animals as fast as they could, the majority of the tainted beasts +were sold and eaten in the second stage or period of the typhus. + +Now, if the flesh of these diseased animals had been eaten raw, +accidents most terrible and appalling would certainly have been the +consequence, although dogs may have fed upon it without injury. But the +cooking of animal flesh at 100 degrees of heat has the property of +destroying for a time the septic germs, as the famous debates now being +held by the experimentalists who are studying the subject of spontaneous +generation tend to show. This poisonous meat, therefore, may at first +have been digested without producing immediate ill effects. + +Our medical practice, however, authorizes us to declare that, after +making every allowance for the influences of this extraordinarily hot +summer, digestive and nervous complaints of the acutest description, and +without any special cause to account for them, have been very numerous +indeed during the last two months, and beyond all proportion greater +than they usually are in London. And we cannot but feel that, if the +cholera should reach the shores of England at this critical conjuncture, +it will find organisms most ready to receive its virus. Then, indeed, if +the typhic miasma come to mix and blend with the choleraic miasma, all +living beings will have to contend with the most deleterious causes of +alterations in their health, and we may (God send it be otherwise!) +witness one of those measureless calamities which, known in former ages +as the _Black Pestilence_, decimated cattle and men indiscriminately, +and which, when we read the sorrowful accounts of it in history, make +the flesh creep with affright. + +We sincerely hope that such misfortunes may be spared us. But ought we +to abstain entirely and absolutely from consuming the flesh of cattle +smitten with typhus? It is a delicate question, but still we shall +answer it, making due allowance for every interest concerned. + +We conceive that all animals which are smitten with the early effects of +the disorder, which begin to operate at the opening of its second +period, that is to say, when the first symptoms are declared, such as +stupor, loss of appetite and shiverings, may be handed over to the +butchers. But this must only be done on the _positive understanding and +condition_ that every animal, sick or not sick, in times of epizootia, +shall pass, either in the farm, the market, or the stable, under the +examination of a competent veterinary inspector, who shall mark the +beast when fit to be sold for consumption. With this precaution, which +at present is put in practice in Belgium, every interest is cared for +and guarded--those of the public health as well as those of the cattle +owners. + +But there is another question of some importance which deserves to fix +our attention for a moment. People sometimes inquire whether the +ox-typhus can be communicated to other animals, and even to man, either +by contact, by direct absorption, or by inhaling the miasma floating in +the atmosphere. + +Experiments of great interest might be made on this subject; but we can +already assert, on the evidence of facts publicly known, that the direct +absorption of putrid matter and purulent secretions, and likewise the +mere contact with tainted flesh, when the epidermis or scarf-skin is +cracked or peeled off, or when the least open sore exists, may give +access to the disease, and produce death, both in man and other animals. +In these cases, the absorbed virus operates, not as a specific agent, +giving birth to typhus, but as a provocative septic agent, endowed with +infectious properties, which infuse into the economy a germ of virulent +and mortal disease. So long as a sound and intact outer skin stands as a +safeguard between us and absorption, we may fearlessly touch and handle +the tainted flesh of these animals. But the slightest sore or abrasion +is an open door to let in death. A young veterinary surgeon, who had a +slight wound in one of his arms, was carried off within forty-eight +hours, as was proved at a coroner's inquest, after he had dissected an +ox which had died of the typhus.[P] + +We see by this fatal example that we must be particularly careful not to +touch an ox tainted with typhus when we carry about us any open sore, +unless we take the utmost precaution in order to guard against all +direct contact or absorption. Man, as we have said and shown, breathes +with comparative impunity an atmosphere laden with the infectious miasma +of this typhus. But that which to-day is true may not be true +to-morrow; let us, therefore, be also on our guard against the too +continuous absorption of an atmosphere impregnated with these +deleterious principles. + +As for herbivorous animals in general, a similar organization must, in +their cases, predispose them to receive the contagion. Whenever we visit +the markets, we cannot help fearing to see the ox typhus communicated to +the sheep and pigs which are stationed around them. It is an +unquestionable fact that, in certain epizootias, all animals without +distinction have been smitten and struck down, and the herbivorous +animals more rapidly than any other. The habit of collecting such vast +numbers of cattle in the same market, and on the same day, though +convenient for business, appears to us injudicious, especially during +the prevalence of this scourge. + +This part of our treatise was in the printer's hands when Mr. Simonds +wrote a letter to the Privy Council which justifies all our +apprehensions. The typhus of the ox has been communicated to a number of +sheep, and we must all expect to see this cruel disease assume much +larger proportions than heretofore, since it has now obtained a second +focus for its maintenance and dissemination. + + "Veterinary Department, 23, New-street, Spring-gardens, + Sept. 25th. + + "SIR,--I beg to report that, acting on the + instructions received from you to investigate without loss + of time the statement received at your office relative to an + outbreak of the cattle plague in a remote part of the county + of Norfolk, supposed to have arisen from cattle having been + in contact with some diseased sheep, recently brought to the + premises, I have visited the district in question, and + inquired into all the circumstances of the case. + + "It appears that as far back as the 17th of August Mr. C. + Temple, farmer and merchant, of Blakeney, received on his + farm 120 lambs which he had instructed a dealer to procure + for him for feeding purposes. + + "The lambs were bought at Thetford-fair on the preceding + day, and were immediately sent by rail to Fakenham, from + which place they were driven to Blakeney, a distance of + about ten miles. On their arrival they appeared to be + fatigued to a greater extent than ordinary, which was, + however, attributed to the heat of the weather and the + exertion the animals had undergone. + + "In addition to this, the shepherd observed that several of + them seemed unwell, and he remarked to his master that they + did not appear to be a 'very healthy lot,' and that he + thought it would be better to return them to the dealer. + Within a day or two of this time the symptoms of illness + were more marked in all the original cases, and many more of + the animals had been attacked. On the 24th two of the worst + cases were removed from the field to the farm premises, and + were placed in a shed for treatment, in which afterwards a + cow was put. On the 25th two of the lambs died, and in + consequence of this, and of the large number which were now + affected, the whole were brought, on the morning of the + 27th, into the same yard where the shed previously alluded + to was situated. There is also another shed, separated from + this yard only by some old furze faggots, into which the + cows were driven night and morning for being milked. The + lambs remained in the yard till the morning of the 28th, + when having had some medicine administered to them, they + were returned to the fold and never came again near the + cows. + + "While in the yard three died, two on the 27th, and one on + the 28th, and on the following day two others died in the + field. From this time the disease went on, so that by + Friday last, the 22nd of September, the day of my visit, + forty-six had either died or been killed, and twenty-seven + were in a very precarious condition. + + "On the 7th of September, ten days after the last exposure + to the sheep, a cow gave evidence of being affected with the + cattle plague, this animal being the one which had been put + into the shed occupied by the diseased sheep on the 24th of + August. A second cow was attacked on the 11th of September, + and a third shortly afterwards, which was followed by + others; so that by the 16th all the cows, six in number, a + heifer, and a calf, were all dead. + + "My examination of the lambs showed that they were + unmistakably the subjects of the plague. The symptoms agreed + in almost every particular with those observed in cattle + affected with the malady, and the _post-mortem_ appearances + were also identical. + + "With a view to ascertain the true nature of the changes + produced in the system prior to death, I had four of the + lambs killed, and from these I took some diseased parts and + forwarded them to the Royal Veterinary College without note + or comment. These parts were examined by my colleague, Mr. + Varnell, who at once recognised the special changes of + structure which are caused by the cattle plague. + + "The whole facts of the case leave not the least doubt of + sheep being liable to the disease termed the cattle plague, + and that when affected they can easily communicate the + malady to the ox tribe; and moreover, that when so conveyed + it proves equally as destructive as when propagated from ox + to ox in the ordinary manner. + + "The case is also more important from having occurred in a + place no less than fourteen miles distant from any other + where the cattle plague exists, thus placing beyond a doubt + the fact of the malady being introduced among the cattle by + the sheep alone. + + "I regret to add that this is not a solitary case of sheep + being affected by the cattle plague. I learned that some + sheep were supposed to be similarly affected belonging to + Mr. R. J. H. Harvey, M.P., on his estate at Crown Point, + near Norwich. This place I also visited, and found a large + flock of upwards of 2000 lambs, among which the malady was + prevailing. A large number had been separated from the + diseased, and gave no evidence of the malady. Very many, + however, had died, and the disease was making rapid + progress. I also examined many of the dead, and found the + _post-mortem_ appearances to be identical with those seen in + the other cases spoken of in this report. + + "In this instance the malady was brought into the estate by + the purchase of some cattle, which afterwards died from the + disease, and which were unfortunately pastured with the + sheep at the time the disease manifested itself. + + "The whole matter is one of the greatest importance, and + which I lose no time in submitting to you for the + information of the Lords of the Council. + + "I have the honour to be, Sir, your most obedient servant, + + "JAS. B. SIMONDS." + + +IV. + + _General Considerations on the Ox-Typhus, and the + Recapitulation of the Symptoms._ + +We have seen the causes, the symptoms, and the cadaveric alterations of +the Bovine typhus, and we may therefore apply ourselves at present to +the consideration of its pathogenia and its nature. Only, the limits of +this book will not admit of a complete discussion of every point of this +important question of pathology; for if we desired to show in what +respect the typhus differs from, and in what respect it resembles, such +and such a morbid entity, febrile, infectious and contagious like it, +such a dissertation would require a whole volume for itself; we are +therefore obliged to keep within certain limits. + +Like every watchful physician who has applied himself to the study of +comparative pathology, we entertained our own preconceived opinions as +to the nature of this _Cattle Plague_. Arguing _à priori_ from what we +knew, from the laws of the pathogenia of those exanthematic diseases +which we have alluded to in a former chapter; from the identity of +variola in various animals; from the preventive treatment to which this +identity has led; believing that animals and man have each their typhoid +fever, as they have their variola or small-pox; considering with the +Ecole de Tours, typhoid fever as a variola of the intestinal mucous +membrane, and having proposed, in 1855,[Q] to adopt inoculation as a +preventive treatment, drawing an easy comparison between the typhus we +are now observing and the typhoid fever in man; hoping, we may say, +indeed, to find in this typhus the inoculative and preventive virus +which is required for our typhoid fever, all will understand with what +eager and vivid curiosity we have examined the entrails of the victims +struck down by this epizootia. For, if this typhus had been a genuine +typhoid fever, the bovine species which has already provided the +preventive virus for small-pox, would equally have afforded us the +preventive virus for typhoid fever. In this hypothesis, our proposal to +inoculate the typhoid fever, which up to this time has been tried on +horses only, and in experiments badly conducted, by pupils of the +Veterinary School of Lyons, was perhaps on the eve of being realised. +But we regret to say, we have been forced to submit to evidence, and to +acknowledge that the present infectious typhus is not the one we require +to provide us with the anti-typhoid virus. + +In the same manner as pathologists disagree as to the question, whether +the typhus and typhoid fever in man are one and the same disease, so +should we long debate, without coming to an agreement, as to that which +relates to the typhus and typhoid fever of the ox. We cannot pretend to +produce a reconciliation between these dissentient schools; all we +desire, is to sum up what observation has suggested to us, on account of +the practical and therapeutic interest belonging to the subject. + +For ourselves, the typhus and the typhoid fever of the ox are two +diseases of the same order, but nevertheless distinct; and the reasons +upon which we ground our opinion are suggested to us by the nature of +the intestinal lesions, the symptoms, and causes of these distempers. + +As we have already seen, the contagious typhus of the ox, at least that +of the present epizootia, is an infectious disease, which varies in the +intensity of the functional disorders and the cadaveric lesions to which +it gives rise. The typhoid fever, we mean the real one,--for there are +other intestinal exanthematic fevers which simulate it,--always localize +on the small intestines a pustulous exanthem, and in the typhus of the +ox, this pustulous exanthem and the ulcerations by which it is +succeeded, are frequently wanting. + +The real typhoid fever springs up in every country under the influence +of local causes, and is not in the same degree infectious and contagious +as the typhus proper. In fine, the typhoid fever smites many species of +animals--the horse, the pig, etc., without transmitting its contagion +with the same intensity. + +The contagious typhus of the ox appears to be more especially proper to +that animal; for in those latitudes where it developes itself other +animals are not affected by it. + +For these reasons, then, to which we could easily add many others, we +consider the typhus of the present epizootia a special and distinct type +of typhic diseases, and differing from the typhoid fever: it is the +highest expression of its class, and occupies the first degree in the +scale of infectious typhic diseases. Next to it we should place the +typhoid fever, which we admit is not often found in the ox. But +veterinary pathology is still less understood than human pathology, and +typhoid fever may perhaps be recognised in those diseases which the +former science has described under the names of _adynamic_ and _ataxic +fevers_. Besides, a persistent research among the veterinary memorials +and reports might possibly enable us to discover some instances in which +the real typhoid fever in the ox had been traced, apart from the +epizootic conditions. Here is an instance of it:-- + +Gellé, in vol. i. page 245 of the _Pathologie Bovine_, quotes the +following abstract which had been forwarded to him by one of his +brethren, on the dissection of an ox, which was made on the 10th of May, +1824:-- + +"_Duodenum._--Uniform redness of the mucous membrane, with thickening, +softening, and petechial spots. In the middle portion were discovered +some of Peyer's glands, small round pustules, whitish at the top, with +a reddish circumference. In some parts contiguous to these pustules lay +ulcerations somewhat extensive, which seemed to be the result of the +softening of the pustules which had preceded them. A dark pus issued +from these ulcerations. The inflammation by which they were attended was +diffused in some places, whilst in others it was circumscribed. In some +parts the intestinal mucous membrane was utterly destroyed. The +mesenteric glands were red and soft." + +Gellé adds:--"I have recorded this interesting narrative, as it may +perhaps serve hereafter to throw light on a point of doctrine." + +The intention which Gellé nurtured at the time, is, we see, now +fulfilled conformably with his object. + +The contagious typhus of the ox not being a real typhoid fever, we shall +not, consequently, be able to borrow from it the preventive virus for +that disease in man. But if these diseases differ, and if it is +difficult, in the present state of science, to assign to them such +distinct characters as to produce a perfect agreement among all medical +writers, we must, however, admit, that to designate the ox-typhus now +before us by the generic name of PLAGUE, after the Germans, who +have given it the name of RINDERPEST, would carry us too far +back. + +Let us acknowledge also, that the denomination of _contagious typhus_, +adopted by the French veterinary doctors, is not, any more than the +designation of TYPHUS FEVER, applied to it by English physicians, +totally free from objection. + +In truth, the various species of typhus whose characteristics we have +already given (see p. 73), are all of them febrile and contagious. +Whoever uses the word _typhus_, speaks of a contagious and febrile +malady, inasmuch as we cannot conceive typhus without its +accompaniments, fever and contagion. But as the prevailing +characteristic of this infectious disease is, above all, its +_contagion_, we have preferred to adopt the name of _contagious typhus_, +without, however, deceiving ourselves as to the value of the +denomination. The final elucidation has not yet been found for these +diseases; at some future day they will be methodically divided and +arranged, and each of them will then receive a special title, which will +remove from the mind that vague uncertainty which at present we regret. + +But if some faults of doctrine are open to debate, no doubt whatever can +exist in the mind as to the morbid individuality of ox-typhus, or the +general conditions of its pathogenia; and we are able to deduce from the +preceding explanation, the following conclusions as so many propositions +definitively settled:-- + +1st. The typhus of the ox is a disease essentially infectious, which is +produced by the absorption of the morbigenous miasma in the air. + +2nd. This typhic miasma is absorbed and engendered by the ox, under the +influence of a number of special deleterious causes. + +3rd. When the miasma has been absorbed and incubation produced, the +disease itself is but a supreme effort of nature--a struggle between the +vital forces and the morbid evolution of the poison, in order to guard +and defend life against the danger which threatens it. + +4th. A malady essentially general, _totius substantiæ_, it directs its +action, in different degrees, over the whole structure, but chiefly on +the nervous centres, on the organs of respiration, and on the digestive +apparatus. + +5th. Its progress is regular; to the latest period of incubation it +succeeds that of the general poisoning of the blood--that of the pyrexia +of general fever--which for a time stops up all the secretions. Then, +the morbid flux is localized according to particular predispositions: +either on the nervous centres, when the animal is struck down at the +outbreak; or on the lungs, when the respiratory derangements become the +leading symptoms; or on the digestive channels, when the train of +typhoid phenomena is observable. + +6th. The period of acute inflammation, which had dried up the sources of +secretion, gives place to that of the depurative and critical +exhalations or secretions; from every mucous membrane, from every +outlet, there issues a mucous discharge, which at first is thin and +clear, but afterwards becomes thick and purulent, and endowed with the +most infectious properties. The intestinal mucous membrane, smitten with +a particular lesion, becomes the seat of a flux extremely copious and +intolerably fetid. Gases, and occasionally purulent deposits, are +developed in the cellular tissue beneath the skin. + +7th. The organism or physical frame, disturbed in the very centres of +life, undergoes a general transformation, a kind of organic +decomposition beforehand, and all the symptoms of reaction are followed +by a period of wasting atony and adynamia, which usher in dissolution or +life's extinction. + +8th. Finally, throughout the whole course of the distemper, one special +functional derangement--_stupor_--has been witnessed as the predominant +symptom, the nervous system being in a manner annihilated in its +functions in consequence of the general infection. + +Such are, in a brief outline, the principal symptoms of this typhus, +which, when once engrafted on the economy, pursues its fatal march, and +no treatment can then arrest its evolution. As in small-pox, so in +typhoid fever and in most general disorders, Nature for a time must be +allowed to exercise her new functions, which succeed each other in due +course, and which the physician must not stop; for if he did, he would +accelerate death; but he must watch with a vigilant eye, in order to +assist the vital powers. + +The medical man, satisfied with these facts, will therefore abandon the +chimerical hope of finding a specific remedy for such a disease. The +virus once absorbed, the frame will endure, and fatally endure, all the +morbid phenomena which must produce and succeed each other. _Against +such a poison no other antidote exists than the poison itself._ And this +will be easily understood. What necessity have we for a specific remedy +to resist a distemper, which carries within itself its preventive +treatment? If it germinates and is propagated, let us not accuse Nature +and render her responsible; our own blindness, the lack of a community +of interests among the people, our social institutions, the still +imperfect state of the exact sciences, &c., amply explain how it is +that we have not yet employed the effectual means we possess, not of +curing it, but preventing it. If we could have our choice between +prevention and cure, should we not naturally take the former? + +Indeed, the sources, the causes which generate the typhic miasma, are +thoroughly well known to us, and these we can avoid. The developed +miasms hang suspended in the air; we may, perhaps, one day destroy them, +if not in the outer atmosphere, at least in the stalls and sheds where +the animals inhale and absorb them. In fine, if we are powerless to +arrest the fell disease when its periods revolve, we may hope at some +future time to act with greater efficiency upon it during its period of +incubation. + +On the other hand, if this formidable disease cannot be stopped in its +progress, does it follow that we should not treat it at all? Certainly +not! Far be such a heresy from our thoughts. What would be the +consequence, if we left to their fate the sufferers from the small-pox, +from typhoid fever, and from typhus itself, instead of watching over +them with the utmost solicitude? If the physician, the enlightened +interpreter of morbid phenomena, did not direct them with a bold and +fearless hand, but abandoned Nature to her helpless course, why, +necessarily, every patient would die, whereas a large number are now +saved. + +That which is true in the case of man, is likewise true in the case of +animals: we are bound to treat them when they are ill. If to-day we +think it more expeditious and more profitable to exterminate them, we +certainly neglect our duty. We are the sovereign masters of animals; +they are the companions of our toils and pleasures, their lives must be +given to preserve our own; but on their well-being and their happiness +our own well-being and happiness also depend. They will return to us the +sufferings and diseases of which they die a hundred times over. Like +ourselves, they die of consumptive, tubercular, cancerous, eruptive, +typhoid, and parasitical diseases. And who can tell whether they have +not communicated these disorders to man, who was, perhaps, originally +exempt from them; and whether they do not continually communicate them +to him? + +What noble pages might be written on the close connexion which exists +between all organized beings, both physically and morally! Let us love +these animals, let us treat them with kindness, and all our other +qualities will be raised by so doing. + +But as a man must belong to the time he lives in, we will take up for a +moment with the doctrines of the economists; we will tolerate the +extermination of diseased animals, as a painful necessity. Our duty is +to seek in the study of the diseases of animals _and in their cure_, the +cure of the disorders which afflict the human species. We shall, +therefore, now proceed to consider the subject of the treatment of +horned cattle, both as relates to preventive and curative medication. + +FOOTNOTES: + +[O] Mr. Simonds has for three months had under his observation a cow +which has lived with impunity among animals sick and dying of the +typhus. And a young calf did not contract the disease for more than +three weeks. + +[P] Another instance of the fatal effects of the terrible disease now +ravaging our flocks and herds of cattle, and resulting in the death of a +veterinary surgeon, has just occurred in the town of Sudbury, Suffolk. + +Last week the epidemic made its appearance in the stock-yard of Mr. +Ruffell, farmer, Melford, and the cases were attended by Mr. Robert John +Plumbly, veterinary surgeon, Sudbury. On Thursday a cow, which was +evidently suffering from the disease, was brought out and shot by Mr. +Plumbly, who afterwards made a partial _post-mortem_ examination of the +carcase. In doing so with a small scalpel his shirt-sleeves became +saturated with blood, &c. from the animal. He returned home, and the +same day was attacked with sickness and acute pains in the head and +chest, accompanied with a soreness in the bones generally. On the +following day he appeared somewhat better, and was able to attend to his +duties, but became worse towards evening, and was confined to his house +on the following day. He considered that he was merely suffering from +the effects of a severe cold, and did not call in medical assistance +till Saturday night. He slept well that night, and seemed somewhat +better on Sunday morning. About two o'clock in the afternoon he got out +of his bed to have it made, when he appeared comparatively strong and in +good spirits; but almost immediately afterwards he was taken in what +seemed to be a fit, and expired in a few minutes, before the surgeon, +who only lived next door, could come to his assistance. It was thought +that death had resulted from apoplexy, and a medical certificate to that +effect was given. Rumours, however, soon becoming current that Mr. +Plumbly's death was caused by the cattle plague, the borough coroner (R. +Ransom, Esq.) directed a _post-mortem_ examination to be made. But, by +this time, so rapid was the spread of the virus through the system that +the body appeared perfectly plague-stricken, and by Tuesday morning, +when the surgeons arrived to examine it, and it was taken out of the +coffin, the corpse scarcely retained the semblance of a human being, the +head and trunk being much swollen and black in colour, the features +quite undistinguishable, and all the flesh converted into a putrid +jelly-like mass. The tissues were completely disintegrated, so that it +was utterly impossible to make any examination. + +An inquest was held on Tuesday afternoon, at the court room, Town Hall, +before the coroner, R. Ransom, Esq., and a jury; Mr. Joseph Barker, +chemist, being chosen foreman. The mayor (S. Higgs, Esq.) and other +gentlemen were present during the whole of the inquiry, which lasted +four hours. + +The jury went and viewed the body, which lay in an outhouse, but were so +overcome with the fearful spectacle that they were permitted by the +coroner to retire to partake of stimulants before they could further +proceed with the inquiry. + +The first witness called was Mr. William Brown, veterinary surgeon, and +partner with the deceased, who deposed to having gone with him to Mr. +Ruffell's farm at Long Melford, on Thursday last, to examine several +cows down with the cattle plague. One was brought out and shot by the +deceased, who proceeded to examine the intestines and viscera, which did +not present the appearances usually observable in advanced stages of the +disease, there being but slight ulceration of the coats of the stomach +and bowels. The lungs were not examined, as the deceased had only a +small scalpel with him. In making incisions in the body the +shirt-sleeves of the deceased became covered with blood, but he did not +prick or cut himself. + +Henrietta Dansie, nurse, was examined, and said that deceased had been +suffering from boils on his right arm, one of which she had poulticed on +Wednesday, the day before he had examined the diseased animal. He +removed the poultice himself, but declined to put on a plaster as the +place was a small one, although not healed. He changed his linen on his +return from Melford; but the same afternoon he was taken with sickness +and vomiting, and complained of acute pains in his head and bones. On +Sunday afternoon, shortly before he died, he wished to have his bed +made, and got out and stood whilst it was being done. He then complained +of faintness, and got into bed again, and witness to revive him washed +his face and hands; in doing so she observed that the nails of one of +the hands which had lain in the bed were turning black. She was about to +give him some pills when she noticed a sudden change come over him; and +thinking he was going to faint or have a fit, she rang for assistance +and went herself for the doctor, who, being from home, another surgeon +residing next door was called in, but by this time the unfortunate +gentleman was quite dead. + +Mr. Maurice Mason, surgeon, said he was called in to see the deceased +the night before he died, and visited him again on Sunday morning, and +ordered him a lotion and leeches for his head and effervescing drinks +(the leeches were not applied). From the appearance of the body and the +evidence which had been adduced, witness was of opinion that the death +of the deceased was caused by the absorption of poisonous virus from the +dead beast. + +Mr. W. B. Smith, surgeon, gave similar evidence, and added that the +tissues of the body were so disintegrated that it would have been +utterly impossible to have made a _post-mortem_ examination. + +After half an hour's consultation the jury returned a verdict, "that +deceased died from the effects of the absorption of virus or poison into +his system upon the occasion of his making a _post-mortem_ examination +of a cow which had died from a certain disease called the cattle +plague." + +The sad occurrence has caused much sensation in the town, the deceased, +who was only 23 years of age, being well known and much respected. + + +[Q] "Appel à des Expériences dans le but d'établir le Traitement +Préservatif de la Fièvre Typhoide et des Maladies infectieuses +inrécidivables, par l'inoculation de leurs produits morbides." Memoire +lu à l'Institut, le 8 Octobre, 1855. Inséré dans la Gazette Hebdomadaire +de Médecine. Paris. + + + + +CHAPTER IV. + +_Treatment and Cure of the Ox-Typhus._ + + +In now addressing ourselves to the treatment, and, as far as human +agency can effect it, to the cure, of this insidious distemper, we +cannot conceal from ourselves, that this is the most difficult, the most +delicate, and, at the same time, the most important division of our +work; for it is to this part, above all, that attention will be +directed. This portion of our task, therefore, will prove especially +arduous; and nothing can give a better notion of the difficulties we +shall have to encounter than the many fruitless attempts which, for +several months past, have been made to overcome them by many ardent +inquirers, stimulated by the best possible intentions. + +This, then, is the moment--if we may be allowed the metaphor--to take +the bull by the horns; and we do so without hesitation. If, like so many +others, we are baffled and overcome in this unequal struggle--if our +strength is not on a level with our desires--we trust we shall be +pardoned. + +Several paths leading to the same end may be followed in this exposition +of the treatment of ox-typhus. After mature reflection, we shall adopt +the one, which will allow us to take the disease at its birth, _ab ovo_; +to study it in all its phases, in its first and second causes, and then +in the successive periods of its development. + +In this manner, we shall be able to give an account of each fact of real +importance mentioned in the foregoing pages, and to comprise within the +treatment whatever is connected either directly or indirectly with the +disease. + +Thus we will relate in so many separate articles,-- + +1st. The means and measures to be employed to meet and resist the first +local causes which may generate the typhus, then the secondary causes +which serve to propagate it. + +2nd. The means of preventing the spread of the disease to animals still +in good health. + +3rd. The means of treating it at its different periods, from the period +of incubation to that of its decline. + +4th. Finally, we shall insert the laws and sanitary regulations which +have been published in England relative to this disease. + +As will be seen, by adopting this method, the whole matter will be +considered consecutively and in regular order; and the reader will +understand that when such a phase of the malady is developed it is +because the preceding one, which is the cause of it, has not been +effectually contended with. + + +I. + + _Means and Measures to be employed to resist the Causes of + the Contagious Typhus of the Bovine Species._ + +We have shown fully and explicitly in what countries of the globe, and +in what particular conditions, the typhus is generated among oxen. We +know that this dire disease has its focus on the banks of great rivers +or lakes, which are periodically overflowed, and on which is deposited a +slime teeming with organic matter; in marshy plains, where the same +natural impurities are fostered; and that these first hotbeds of the +evil are found in China, in India, in America, in Africa, as well as on +the shores of the Black Sea. A spirit of observation which delights in +measuring the phenomena of nature with the contracted compass of its own +short views and conceptions, could alone have imagined that the +ox-typhus was only to be found originally in the steppes of Hungary and +Russia, and that the bovine species of those countries, thanks to a +special organization, was alone capable of generating the typhus. + +Since we know, then, in what conditions this disease is developed, and +especially in what manner it is propagated in Europe, it is not +impossible now, when nations are united by the means of quick and easy +communication, by commercial treaties, and by the mutual relations of +science, to examine what measures might be taken to modify and control +these conditions. A commission formed for this purpose, a scientific +congress, would be able to make on the spot a study of all the +circumstances which favour the development of typhus, and the result of +their reports would enlighten the peoples as to the causes which produce +it and from which they are first to suffer. They would be recommended to +choose as pastures the healthiest places, to withdraw their cattle at +certain seasons from those plots of ground which are baleful to them; +new systems of agriculture would be planned and tried, &c. These +questions being carefully examined, might lead to important results; nor +can we understand how, in the age in which we live, the same +indifference and apathy as prevailed in the past should be maintained in +presence of the positive and permanent causes of this infectious +disease, whose contagion, as we now see by many proofs, may extend at +once to so large a portion of Europe. There is now something to be done +in this matter; it is the duty of the governments to deal with it +effectually, and to take serious measures to destroy the evil radically, +if radically it can be destroyed, and, if not, to alleviate its +pernicious effects as much as possible. + +Moreover, many breeders of cattle have not waited until now to guard +against some of the first causes of the typhus: already they give the +animals rock salt, ferruginous and arsenical preparations, but all this +is done without method, and according to each man's will and pleasure. +It would, therefore, be necessary to institute regulations, and to see +them carried out and practised under the superintendence of public +functionaries, armed with sufficient power and authority. + +These measures having been taken, others no less indispensable ought to +follow. They should determine for the herds of cattle intended for +exportation, the ways and channels they must travel by to go to any +central part or to any railway station; and there the inspectors on duty +should mark every animal that passes out of the district he is leaving. +Heavy penalties should be inflicted on all who might infringe these +rules. + +These precautions would contribute in part to arrest the propagation of +the complaint; but there is another measure more radical and effectual, +which should be taken in order to prevent its extension--we mean +inoculation, which has met with complete success in some of the +governments of Russia. + +Thus we see, there are powerful means of withstanding the production of +the disease in its focus, or generative bed, and likewise its extension +among the herds of neighbouring countries; and these latter might render +them in some sort obligatory, by refusing most rigidly to admit to their +markets, as in Italy has sometimes been done, every head of cattle which +was not marked as inoculated or which was not furnished with a permit of +health. + +It is easy to conceive that those countries wherein the ox-typhus has +its birth, and for which the breeding of cattle and their exportation +are a great source of wealth, would soon feel that they are more +interested than any other in stifling the contagion in its focus, and in +affording to those countries that receive their herds, every security +and guarantee which they have a right to expect. Interest in this case +coming to the help of common sense, very satisfactory results would in +course of time be obtained. + +Moreover, we are conscious that we are here dealing with very +complicated questions; for, though in a book they may seem simple and +easy, their application is a matter of extreme difficulty. We know too +well that these preventive measures for protecting animals will meet +with many obstacles, and only be adopted at last with tardy reluctance, +since man himself continues in some respect indifferent to the causes +which spread about the fearful epidemics to which he falls a victim in +consequence of his neglect. + +In truth, it is well known that the cholera of the present day--that +much more serious _plague_--had its origin on the banks of the Red Sea, +amidst the infectious miasmata developed near Mecca, where thousands of +pilgrims who had died of fatigue and privation, and hundreds of +thousands of sheep butchered and religiously offered up in sacrifice, +have, beneath a torrid heat, generated the choleraic miasma, which +formerly was supposed to be produced exclusively on the banks of the +Ganges. This fact duly ascertained and proved, we might suppose that the +governments of the different nations among which the cholera is about to +extend its ravages, were indignant and had complained at thus being +smitten with a scourge, due to the careless ignorance and sordid avidity +of some official of the Turkish Government. But we should be mistaken. + +No! every one hoped at first that he, at least, would be spared by the +contagion, and the authorities did nothing to resist the evil but adopt +the old course of _quarantine_--a remedy more illusory now than ever, +since the nations are in constant communication, either in their own +persons or by the exchange of their commodities; and consequently, the +epidemic is pursuing its invading course from week to week. + +That which is being done for the cholera gives us a scale by which we +may estimate the efforts which will be made to arrest the generation and +the contagion of the cattle typhus.[R] + +We are certainly bound to resist the introduction of horned cattle +tainted with typhus; but in the conditions amidst which they live, some +of them may bear the seeds of the distemper, even whilst they appear in +perfect health, and therefore able to endure the fatigue of a long +journey. + +Now, in order to avoid exciting the incubation of the typhus during +their transit either to Finland, Holland, France, or England, it must +never be forgotten that these animals are gifted with a nervous +sensibility of wonderful acuteness, joined to the weakest vital +resistance. Care must be taken to husband their strength, to give them a +choice distribution of food easy of assimilation; barley-meal, or other +grains, must be mixed up with their drink; they must be protected from +the changes of weather; they must have room enough and air enough in the +locomotive stalls on the railway trains and on board ship. + +We pass over in silence the hygienic measures to be taken in order to +keep these vehicles of transit in a proper sanitary state: the sanitary +police regulations inserted further on will make them sufficiently +known. + +All these measures having been taken to meet and withstand distant +causes and dangers, let us now direct our attention to those local +causes which strike our eyes, and which likewise have their share of +influence in propagating the disease. Thus, whenever an inclement season +comes to deprive the herbivorous animals of sufficient pasture, or to +deteriorate its natural qualities, we are bound to remedy this change, +and to increase the cares we devote to them; for these frail and +helpless creatures, immediately feel and suffer from the effects of a +sustenance less than usually restorative. Under such circumstances, we +must make exceptional sacrifices; when they return from feeding on the +grass, we should give them some additional fodder, or roots of a +generous quality. We must imitate the regimen used in the country of the +steppes, by adding to their forage a solution of marine salt, or a +solution of sulphate of iron. Day by day we must give to the weakest and +least fed cattle, a ration consisting of bruised oats, pounded juniper +berries, gentian, sulphate of iron, and carbonate of soda. + +For, if we neglect to take those measures which are required to prevent +among herbivorous animals the development of those ordinary epizootias, +which every year are generated on our own soil, they will certainly +afford a favourable seat to the typhic miasma transmitted by foreign +animals, or exceptionally generated by themselves. These cares and +attentions must be greatly increased, when the foreign epizootia, has +spread itself, as in the present instance, among our flocks and herds. +Then, indeed, we must be careful not to load these creatures with +pampering food for the purpose of fattening them. For it may be +profitable, and the breeder may plume himself, on having produced an +adipose monstrosity to such a degree as to bury, for instance, a pig's +head in the fleshy exuberance of his thorax; but such a derogation from +the laws of nature borders closely on disease, and assuredly such an +unnatural accumulation, predisposes the glutted animals to epizootic +diseases in general. + +The water given them to drink must be attended to with particular +solicitude. It should never be drawn up from ponds or stagnant rivers. +The animals kept in the pasture grounds should always find at their +disposal, in receptacles intended for their use, a supply of pure fresh +water. + +After these precautions with respect to their food and sustenance, +attention must next be directed to the hygienic conditions required by +the animal. Every morning he should be cleaned, washed, brushed, and +dried; what is every day done for the horse must now be done for the ox. +These unusual cares will be most salutary to him, and greatly increase +his vital resistance. + +The animal thus protected in his food and particular necessities, +attention must next be directed to the stalls and sheds. Over-crowding +must be carefully avoided; the proper cube of air for breathing must be +measured out for each head of cattle; every day the latter must be +carried out into the open air; the floor of the stall or shed must first +be thoroughly cleansed and washed out, after which it must be sprinkled +with a solution of chloride of lime. If the stall is not well aired, a +little straw should be burned on the ground, to improve the atmosphere, +or else branches of resinous trees, or juniper berries may be used. In +some cases aromatic fumigations of sage, rosemary, or mint, boiled in +water, are employed, the balsamic vapours which arise therefrom being at +once tonic and purifying. During the night a tub, containing pitch and +tar, should be left in the stall, or a large piece of camphor should be +suspended from the ceiling. Vinegar may be spilt on a piece of red-hot +iron, or powder of sulphur may be burned into sulphuric gas and diffuse +its vapours through the stall or shed. This excellent parasiticide may +perhaps be equally endowed with anti-typhic properties. + +Finally, when this fatal epizootia is ravaging the country, every farmer +and agriculturist must carefully abstain from mixing with his herds any +cattle which have been bought either at fairs or markets; he must take +care, conformably with the directions issued by the Privy Council, (to +which we refer the reader for more ample details,) to avoid all contact +both direct and indirect with horned cattle tainted with the typhus, as +he might himself become an instrument of the contagion.--Let him never +forget that to take as the guide for his actions in these times of +calamity his private and personal interest, is the greatest crime a man +can commit. Let him strive, therefore, to assist the authorities in the +measures which they have taken for the interest of all. + + +II. + +Now that we have examined the measures which prudence directs us to take +to defend ourselves against the causes which produce and propagate +typhus, let us think of the means of preventing it, when the contagion +threatens to diffuse itself over a whole kingdom, as at present it is +doing in England. + +When, on the 19th of last June, it was believed that the typhus or +Cattle Plague, as they continue to call it, had effected its invasion in +England, the Government, informed by professional men of the serious +danger to which the interests of the country would be exposed, if the +disease should spread, might have considered this distemper not as a +question of private interest, but as one of public and national concern. +It might at the outset have given to this epizootia all the significancy +of a public calamity, have looked upon it as the invasion of an enemy +threatening to destroy its territory, and have employed every possible +means to stifle it at its birth. + +We well know that the English Government, derived as it is rather from +political than from religious and social changes, is at once +monarchical, aristocratic, and partially democratic, and for that reason +embarrassed in its working by so many wheels. Its authority is scattered +and divided, whilst the respect ascribed to the prerogatives of each +distinct public power is the safeguard of the State. In the absence of +both Houses during the recess, it could take no resolution as to ways +and means; for the difficulties on this unhappy occasion, we cannot too +often repeat it, are reduced to a question of money. Deprived of the +requisite authority, it was unable to do more than exhume the old laws +on the matter and ordain new ones. And yet, the impotence of the +Government was not perhaps so great as is imagined; for whilst it +suffered the typhus almost unmolested to devastate the country, it very +justly, and in the name of the public interest, took vigorous and +effectual measures to stamp out another epidemic--the rash and insane +conspiracy of the Fenians. It stood still and would not authorize +domiciliary visits in stables and stalls, nor the seizure of sick +animals, but it did not falter a moment at the domiciliary visits and +incarceration of insurgent citizens meditating mischief, so that in +this instance, the privilege of immunity has been given to the brute +creation. Everybody, both in England and out of England, admires their +vigour and despatch in stifling the insurrection in its bud. But why not +act with equal promptitude in the case of an epizootia? + +Arming itself, in this manner, in the public interest, and with +sufficient power, the Government might have appointed an executive +commission, with the Lord Mayor as president. Such a commission would +have applied itself at once to the consideration and studious +examination of the subject in all its bearings, and would have proposed +prompt and energetic measures, which the Government, with equal +despatch, would have confirmed by giving to them the authority of law, +as they have since tardily done. A fund, which, for the wealth of +England, would not have been considerable, 250,000_l._--the cost of a +few Armstrong guns--might have been placed at the disposal of this +Board, to enable its directors to meet and provide for, without delay, +every just claim and want arising from the scourge. + +An auxiliary commission, exclusively medical, and consisting of medical +and veterinary doctors, might have been formed conjointly with the +former, and every preventive measure, considered by them as necessary to +stamp out the complaint at the outbreak, after it had been proposed by +the medical board, and submitted to the executive commission, and by +them to the Home Secretary, might have been acted upon by law within +twenty-four hours. + +Taken unawares, and the mode of treating the sick animals not being +known at first, they would have been reduced to the cruel necessity of +exterminating at once all tainted cattle, as well as those belonging to +tainted herds, but not without compensating the owners of those +cattle.[S] + +They would have sent two physicians to Russia and Hungary, to observe +and study the preventive and curative medication, especially their mode +of inoculation, and thanks to the rapid locomotion of these times, +twenty days would have been sufficient for this foreign exploration. +The physicians constituting the medical board should have been +authorized to seize any beast tainted with the typhus; a company should +have been charged to collect and keep ready for the public service, at +the four quarters of London, an ample retinue of horses, closed +carriages, and working men, to convey at all hours of the day and night +the carcases of the slaughtered animals to the respective spots, where +long and deep trenches had been dug to receive them. Each carcase before +burial to have been well sprinkled with chloride of lime. + +By taking this course, every one's interest would have been respected, +as much as can be desired when a great calamity threatens a country; +besides, in doing so, the present ministers would but have followed the +example of the Government (with regard to compensation), during the +epizootia of the eighteenth century. The proprietors who had thus +received, not the full and absolute price, but a sum sufficiently +remunerative for their sacrificed cattle, would have assisted the +authorities, and thereby would have served the common interest, because +their sick cattle, perishing every hour within their stalls and sheds, +were no longer a real source of embarrassment and ruin. They would not +have been obliged to drive them to market to get what they could out of +them and disencumber themselves. The most active cause of the contagion +would by this means have been prevented. + +This allowance having been made for the most pressing dangers, attention +should next have been directed to a matter no less important--we mean +the treatment and cure of this distemper; for we will never admit that +England can have fallen back a century, and that whilst those +enlightened men--Malcolm Flemming and Layard--proposed and tried to cure +and prevent ox-typhus in 1757, we, in 1865, shall have been reduced to +the horrible alternative, the repugnant barbarity, of the general and +indiscriminate extermination of the tainted cattle. + +Whilst, therefore, the treatment of the typhus would have been studied +on the spot, and the most urgent measures would have been taken to +withstand the propagation of the evil, they would have established, a +few miles from London and on the northern side, in the direction of the +great cattle market, a number of hospitals or sanitariums, and, as far +as possible, within a park. These hospitals, constructed of wood, +containing, besides stables and sheds, a slaughter-house, a +dwelling-house for the staff of employés, a laboratory stocked with all +the physical and chemical instruments required, &c., would in two or +three weeks have been sufficiently prepared to receive a certain number +of cattle. + +Provided with these advantages and opportunities, a permanent stage of +operation would have been raised on which trials and experiments might +have been made with every chance of fruitful results. In these +sanitariums, for instance, the most practical physicians and +veterinarians might have entered upon a systematic course of treatment, +dividing the bovine patients into classes, according to their periods of +disease, their age, &c.; and trying some particular mode of treatment, +some remedy considered as effectual, alternately, upon each of these +classes of tainted cattle. These experiments, having been made under +circumstances so favourable, would have enabled the faculty to +establish a medical basis, which, if not infallible, would have been +relatively efficacious, and might have saved a large number of the +infected animals. + +Whilst thus fixing their attention on the cure of the sick animals, +these experimentalists would have carefully studied and practised the +preventive treatment by inoculation, availing themselves both of +Layard's hints and recommendations and of the practical knowledge +acquired by the medical expedition to the steppes, which would by that +time have returned from their mission. They would have selected animals +smitten with the genuine typhus, of the typhoid and intestinal form, in +_the third period_, whilst the depurative and critical secretions are +running from the mucous membranes; they would have gathered the virus +from its springs of infection or from its purulent subcutaneous deposits +or from the serum of the blood. + +On the other hand, they might have chosen four heifers, of good +constitutions and healthy, and these they might have prepared, according +to Layard's advice, for inoculation, by a special treatment, and by +hygienic and medical cares. On some of these the inoculation would have +been made near the tail, according to the subcutaneous process, with a +lancet charged with typhic virus; on others, a crucial incision, or +cross-cut, would have been made on the crupper. But, to speak truth, we +cannot do better than Layard, whose ingenious treatment, with all due +deference to a certain veterinarian of our day, deserves a very +different epithet than that of being amusing.[T] Layard says:-- + + "That nothing may be omitted which in any shape can + contribute to the success of inoculation, due attention + should be paid to the constitution and state of the beast, + no less in this practice on the cattle than on the human + species. Undoubtedly the young, healthy, and strong bid + fairer for a good issue than the old, sickly, and feeble; + each of these different constitutions demand a particular + treatment, even in the method of preparation; and however + trifling it may seem to many--the urging a necessity of + preparation--I will venture to affirm that I have seen + excellent effects arising from a rational preparation, and + fatal events from want of preparation. I have likewise been + witness of unfavourable turns, merely from an injudicious + preparation. + + "The beasts which are sanguine require moderate bleeding; + those that have but a small share of blood must have none + drawn. The strong must, besides moderate bleeding and + purging, be kept on light diet and their body kept open. + Thus, scalded bran, mixed with their hay and chaff; will + cool them. The weakly, and such as are inclined to scour, + must be kept on dry fodder, and have peas and beans given + them to strengthen them. A mess of malt, or a quart of warm + ale, with a few spices, will be very suitable for them. + + "Whatever diseases the cattle be affected with, if time will + permit, they are first to be removed. + + "The cattle to be inoculated are first to be well washed, + rubbed dry, and then curried, to remove all the filth from + the hair and skin. Then they are to be placed in a spacious + barn or stable, where the air is temperate and no cold can + come to them. There they are to be prepared according to the + direction already given, foddered with good sweet hay, and + watered with clear spring water; and if the distemper be not + near they may be turned out into the air, near the barn or + stable, and may stay there a few hours in the middle of the + day. + + "When it appears that the cattle are in perfect health, free + from any infection or other disease, brisk and lively, + neither costive nor scouring, and chewing their cud, then + the operation may be safely undertaken, and henceforth they + must be confined to the barn. + + "Since there is observed to follow the greatest flow of the + contagious and putrid particles separated from the blood, + wherever the infectious matter makes an impression at first, + particular care must be taken not to inoculate near such + vital parts as the heart and lungs, nor near the womb, if a + cow with calf be inoculated; for, though rowels are properly + applied in the dewlaps, to draw off the pestilential humour + from the breast, and in other cases beasts are frequently + rowelled in the flanks,--yet in this operation, as matter is + inserted by these channels into the neighbouring vessels, + those vital parts, or the womb, might become the chief seat + of the disease, and the event prove fatal. + + "To prevent such accidents, human beings have been + inoculated on the arms and legs, and now-a-days the arms are + found sufficient. I would recommend that the cattle should + be inoculated about the middle of the shoulders or buttocks, + on both sides, to have the benefit of two drains. The skin + is to be cut lengthways two inches, deep enough for the + blood to start, but not to bleed much. In this incision is + to be put a dossil or pledget of tow, dipped in the matter + of a boil full ripe, opened in the back of a young calf + recovering from the distemper. It may not be amiss to stitch + up the wound, to keep the tow in, and let it remain + forty-eight hours. Then the stitches are to be cut, the tow + taken out, and the wound dressed with yellow basilicon + ointment, or one made with turpentine and yolk of egg, + spread on pledgets of tow. These dressings are to be + continued during the whole illness, and till after the + recovery of the beast, to promote the discharge; and then + the wound may be healed with the cerate of lapis + calaminaris, or any other. + + "On the third day after inoculation, the discolouring of the + wound, whose lips appear grey and swollen, will be a sign + that the inoculation has succeeded; but the beasts, as + Professor Swenke informs us, did not fall ill till the sixth + day, which answers exactly to the observations daily made in + the inoculating of children. Yet the Professor adds that on + the third day a costiveness came on, which was removed by + giving each calf three ounces of Epsom salts. + + "No sooner do the symptoms of heaviness and stupidity appear + than the beasts must have a light covering thrown over them, + and at night fastened loosely. They must be rubbed morning + and evening, and curried, till the boils begin to rise; warm + hay-water and vinegar-whey must be given plentifully. Should + the beasts require more nourishment, dry meat, such as hay, + with a little bran, may be offered. I should be very + cautious in giving milk-pottage, even after the boils and + pimples had all come out, for fear of bringing on a + scouring. However, this caution is proper, that whenever + milk-pottage be given the vinegar-whey is to be omitted for + obvious reasons. In cases of accident, the same attention is + to be observed in the disease by inoculation as in the + natural way, and the medicines recommended are the same I + would use; but by inoculation there seldom is a call for + any, so favourably does the distemper proceed through its + several stages. + + "The crisis being over, it will be proper to purge the + cattle, to air them by degrees, and to have the same regard + in the management of them as is laid down in the chapter on + the method of cure." + +The typhic virus is so highly infectious and poisonous that the first +animals inoculated would have all died; it would have been necessary to +inoculate successively a number of animals with the virus derived from +the first inoculation, and transmitted from an inoculated animal to a +healthy one, by which means they would have acquired a virus of the +first, second, third generation, and so on. These inoculations having +always been made on four animals at a time; on two of them, the disease +would have been left to take its own course, in order that the +experimentalists might watch its progress and development, and the two +others would have supplied the virus for inoculation. + +At the third or fourth generation, the virus, modified and attenuated in +its infectious principles, would no longer have been mortal in its +effects, as experience has proved in Russia. Then the inoculated +animals, placed under the control of hygienic cares and a few purgative +and tonic medications, would have passed from convalescence to health. +The virus thus attenuated would have supplied the means of a practical +inoculation on a large scale to all healthy animals. + +Proceeding thus, they would, moreover, but have followed the method +adopted in those times of epidemic and epizootia when the small-pox is +raging. On those occasions, we subject our sick patients to vaccination +or revaccination; we inoculate the variola in our sheep threatened with +the contagion; we pursue the same course in cases of epizootia, of +peripneumonia. And truly, that which it is reasonable to do in one case +may be generalized and applied to a greater number. + +The experiment we have suggested might, perhaps, have been long and +difficult, nay, even costly, but we should have established, after a +certain time, the rational method of this preventive treatment, and have +distributed the same throughout the country. Veterinarians would have +formed in particular districts their centre of operation, in which the +preventive virus might have been produced, and they might have gone from +farm-house to farm-house to inoculate all the cattle within them. + +From these facts and observations made by the physicians, precious +documents would have been derived; and if, contrary to all expectation, +success had not justified every hope, we should have bequeathed to +future generations facts and experiences which would have been of the +most useful character to them and full of instruction. Thus it is that +science advances and progress is accomplished. + +If all that we have just indicated as a realizable matter had been done, +in effect, England would have afforded in this, as she has so often done +in other cases, a noble example to be followed, and would have acquired +a new title to the admiration of other nations. + +But, unfortunately it has not been so: silence has succeeded to +eloquence at Guildhall, and the meetings at the Mansion-house have +flickered away. That which was held on the 27th of September, seems +likely to be the last of them.[U] + +The subscriptions which, in spite of all the praiseworthy efforts and +earnestness of the Lord Mayor, did not reach 2000_l._, were returned to +the subscribers, so that all the attempts which have been made to +centralize the direction to be given to the various measures have proved +abortive. The plan of forming sanitariums, as well as that of +compensating the owners of cattle, have both fallen to the ground. + +What can we think of such a state of things when we see the ox-typhus +extending its ravages to sheep, and have to fear that the disease will +spread to other animal species? What serious reflections it creates in +our minds, and what awful consequences we might deduce therefrom! But +what would be the use of them? + +Let us add, however, that France, save on the recognised principle of +indemnification, and a more speedy extermination of her tainted cattle, +has shown the same deficiency as to the means of treatment as England; +whilst we have the consolation of attributing this impotence on the part +of this country to the fact that the outbreak of the epizootia has +occurred during the Parliamentary recess. + +It is, therefore, to institutions rather than to individuals that we +must ascribe the impossibility of conquering the difficulties which have +been met, and which at any other time might not have obstructed the +course of things. Far be it from us therefore to accuse of indifference +a great people renowned for their zealous promotion of public interests, +for their charity and inexhaustible philanthropy, whose innumerable +asylums have been opened to every misfortune, who support so many +hospitals and public charities by their voluntary contributions, and +who, in so many calamities, have seen some devoted heroine issue from +her retirement to assuage them. For if the Crimean war produced its lady +beneficent in the person of Florence Nightingale, all of us must allow +that if others had followed the example of Miss Burdett Coutts, who, in +a manner, has stood alone against the storm, by the facilities she has +afforded for treating and experimentalizing on the cattle smitten with +typhus, the formidable scourge might have been arrested in its focus. + + +III. + +_Curative Medication._ + +We might acquire the means of resisting the general causes which develop +the typhus; we might stop its diffusion, we might even prevent it, by +inoculating the sound and healthy animals, and yet it would be +necessary, none the less, to search for the means of curing it; for, as +in the small-pox, the preventive treatment of which we know, certain +circumstances would arise in the disease which would oblige us to treat +it. And as we are far from being able to resist the generation and +dissemination of this scourge, which reckons almost as many victims as +sufferers, it is important to make known what treatment we can oppose to +the functional derangements to which it gives rise. + +As we have already said, this typhus, when the organism has absorbed its +peccant and infectious miasma, produces a succession of disorders which +become in a manner temporary functions; it pursues its phases, its +periods; and as the functional derangements differ at these several +epochs from the development of the morbid phenomena, the course of +medicine which is employed to check them cannot always be the same. +Starting, therefore, from practical data, we will attend the disease in +its gradual advance--that is to say, in its distinct periods--and will +afterwards explain certain predominant symptoms, which, owing to their +importance, must likewise fix the attention of the careful therapeutist. + +It will be remembered that we have recognised four periods in the +regular course of typhus:-- + + 1st, a period of incubation; + 2nd, a period of initiation; + 3rd, a period of duration; + 4th, a period of decline. + +But, in the first place, before beginning the treatment, every farmer or +grazier, or cattle-owner, who keeps a certain number of cattle, should +divide his herd into several classes, in order to regulate and methodize +the cares to be given to the sick. + +Thus, he will form a first class, comprising the animals in a sound and +healthy state, having had no intercourse, either direct or indirect, +with the tainted cattle, and which he will be careful immediately to +isolate and keep apart. + +A second class must be formed of those beasts, which, though as yet +unaffected with the distemper, have, nevertheless, been exposed more or +less directly to its contagion, by living and consorting with them, or +by their contact with other animals, either at fairs or markets, or in +the ships and cattle-trucks on the railway during their transit from one +place to another. The horned cattle composing this latter class must be +carefully watched, and be made the subject of the preventive treatment, +the moment the first sign appears of the working of the incubation. + +A third class must be formed, consisting of cattle actually smitten with +the distemper. + +These divisions of animals being thus settled and separated, will +diminish the labour and the cost of treatment and the liability to +diffuse the complaint, especially when the epizootia begins to lose its +virulence. + + +_First Period--of Incubation._ + +We have said that infectious diseases, when once the frame had suffered +the effects of the poisonous miasma, pursued their fatal course, and +that, generally speaking, it was impossible after such infection to +arrest its development. We say generally, for the typhus at the outbreak +of its appearance on a virgin soil sometimes manifests itself in a +benignant manner, then it becomes more destructive, by-and-bye its +pernicious properties decline, and it in some sort goes out of itself. +One would say that the epizootia, like those it smites, has likewise its +peculiarities, its period of initiation, of duration, and of decline. +There are in consequence fixed times or epochs during which the +sufferers afford better scope for our means of action; at a given moment +the attenuated virus, having lost much of its deadly effects, ceases to +produce death, which decline is the real source of the marvellous +successes obtained by certain remedies against the epizootia. + +If it be true that the distemper at its period of duration, and at its +most critical moment, cannot be fettered, we should not be justified in +asserting positively the same, as respects the period of incubation. +Indeed, we are convinced ourselves, that if ever this disease shall be +clogged in the wheel, _if ever its specific remedy shall be discovered, +it will be within the period of incubation_, when the economy begins to +struggle with the first phenomena of the poisoning. Be that as it may, +we cannot, in epizootic times, too earnestly enjoin the owners of cattle +to submit their animals to a strict and close inspection, in order that, +when the first signs of incubation appear, they may modify the animal's +usual diet, and attack the disease at its birth, so as to render it +abortive, if the thing can be done. + +At this period we must endeavour to come to Nature's assistance, we must +shake and stir up the economy, we must unseat the morbid functions which +seek to master us, and then the vital force, thus solicited and +stimulated, may sometimes struggle with advantage. To do this +effectually, if the animal is atonic and predisposed to adynamia, if his +internal organs are relaxed, we will strengthen him by administering +every day a stimulating beverage. If he is confined to the stall we +will give him the open air, and let him graze the fields; which is a +treatment by itself for the invalid animal, so vivifying is the pure air +of the common, and so thoroughly different from the atmosphere which is +pent up within his stall. If the animal is strong, lusty, exuberant with +health, let him be purged once or twice, the purgative to be given at +intervals of twenty-four hours. (We shall give the medical formula in +the chapter addressed to farmers, graziers, &c.) + +This purgation, moreover, will correspond with the theory of those +authors who consider the evacuations as the proper means of delivering +the economy from the infectious miasms which have been absorbed. + +If the beast is plethoric, recourse should sometimes be had to bleeding, +especially in hot and dry seasons, like the one we have recently passed +through. + +These stimulative and depletive medications cannot but be favourable to +the animal, since it will anticipate the treatment to which he must be +submitted a few days later, when the disease shall have declared +itself. + +To this treatment, in some sort preventive, must be annexed an +_antimiasmatic_ beverage, either a _permanganate of potash_, or a +solution of _chlorate of potash_, or of _arsenic acid_ in powder, mixed +with some aromatized beverage, or solution of _arseniate of soda_. These +anti-typhic drinks must be discontinued on those days when the sick +cattle are purged. + +It need hardly be said, that during this period of incubation the +feeding of the cattle must be strictly attended to, and that the animal +must receive unusual hygienic care. + + +_Second Period, or that of Initiation._ + +At this period the constitution and temperament of the sick cattle must +first of all be deliberately studied, so as to ascertain fully which are +_lymphatic_, which are _nervous_, and which are _sanguine_. We must +notice the age, the sex, the state of gestation, and make allowance for +any prior complaints to which any of the sick cattle may have been +subject. For if, like certain system-mongers, we reduced the treatment +of all tainted cattle to the same mathematical formula of medication, +that is, either to bleeding or to purging exclusively, we should +certainly increase the number of victims. + +In this stage of the disease we have to contend with the derangements of +the circulation and secretions. The fever is generally intense, the +blood is inflamed or vitiated, the mucous membranes are dried up; +shiverings, alternations of cold and heat, &c., occur. We must then +mitigate these morbid phenomena either by bleeding or purging. The +bleeding must be more or less copious, according to the strength of the +animal. For, it must not be forgotten that we have several critical +phases to pass through, and if we exhaust the animal by too largely +draining him of blood, we may forfeit the success of the treatment. If +bleeding is considered unnecessary, let the sufferer be purged at once, +by administering either _sulphate of magnesia_ (_Epsom salts_), _or +sulphate of soda_ (_Glauber's salt_). These purges to be taken daily, +for two or three days, according to the way they operate. Linseed oil, +mixed in some warm beverage, may be given instead of these, or else a +mixture of rhubarb and calomel, or even a decoction of senna. Preference +should be given to saline or laxative purges, as, drastic purgatives, +such as aloes or jalap, sometimes concentrate the inflammation on the +narrow parts of the digestive channels. + +In this second stage--the period of initiation--the appetite is +generally gone, the thirst excessive; so that nutritive or solid feeding +must of course be suppressed. + +As for the drinks, they must be cold, consisting of water with +sufficient flour mixed in it to whiten it, and a little vinegar or +sulphuric acid, to acidulate it. A decoction of good hay with some +marine salt, or nitrate of potash; a decoction of pellitory or +wall-wort, of ground-ivy, or whey, or buttermilk, likewise acidulated, +and which the cattle are very partial to, will in every way be suitable +for their use. If the heat of the skin diminishes, and if congestion +appears to settle on the lungs, the drinks must be given warm, +consisting of a decoction of borage leaves, mallows, marsh-mallow, and +pellitory. In these cases, the body must be protected from chills by +overlaying it with blankets, so as to keep the mass of the blood as much +as possible on the surface, and check the tendency it has to load the +internal organs. + +By following these prescriptions, we shall answer all the conditions of +the treatment during the second period. In truth, by the process of +bleeding, we shall have reduced the heat of the fever, and prevented too +great a flow towards the nervous, pulmonary, or digestive centres. The +purgings will have acted with similar effects; and, what is more, they +will have cleared the _primæ viæ_, and rendered the circulation of the +abdominal apparatus more easy. In fine, the drinks will have contributed +to assuage the violence of the fever. The washing, which must be +effected with a wet sponge passed over the nose, mouth, and eyes, and +then over the skin, which must afterwards be rubbed dry, will be both +useful and pleasant to the sick animal. This cleansing will maintain the +important functions of the skin in due order. + +Some persons have advocated as most efficacious at this period +hydro-therapia, or the Water-cure, in the form of warm and cold +ablutions, vapour baths, &c. This treatment, so bracing by its revulsive +action, and the powerful influence of which we witnessed for several +years in the establishment which we superintended at Belle Vue, near +Paris, might prove of some service in ox-typhus, especially in the form +of the vapour bath; but it requires so much practice, and so incessant +and watchful a care, that it is needful to have the process attended by +an experienced practitioner. + +We must remark, in addition, that the general state of the animal, and +his desire for food, will show the degree of strictness and restraint +which must be observed in regulating his diet. His instinct must be +taken by us as a guide; and if the drinks rendered nutritive by the +addition of bran, oatmeal, barley flour, or even seed of grass pounded, +are relished by him, we must indulge his desires to some extent, in +order to keep up his strength. + + +_Third Period, or that of Duration._ + +At this stage of the distemper we must watch and follow step by step the +symptoms which attend it, and come to their relief. + +All the secretions have now resumed their course; from the mucous +membranes there occurs a copious discharge, first of all serous, then +thick and muco-purulent; the breathing may be obstructed, the +diarrhoea frequent; the air infiltrates beneath the integument. The +fever is sometimes continuous, sometimes intermittent. We must satisfy +the cravings of the vital powers by administering the same beverages as +in the preceding period. Far from checking the diarrhoea, as some +advise, we must regulate the evacuations by means of laxatives, such as +tartrate of potash, sulphate of magnesia, or sulphate of soda. It is +very essential, indeed, that the mucous membranes of the digestive +channels should be free, and not irritated by the contact of solid +alimentary substances or bilious secretions. + +If the diarrhoea be too frequent or irritating, we must give the +sufferer night and morning a clyster, consisting of bran water. + +At this period we will follow the advice given over and over again by +all the physicians of the last century, and apply cauteries with red-hot +iron, or fix one or two setons either on the dewlap, the neck, or the +thighs, and these issues must be kept open by means of basilicon +ointment. It is unquestionably of the highest importance to promote all +the depurative secretions in animals whose cellular tissue is choked up +with grease and lymph. Those only have got well in which the running has +been regular and copious, and the wasting of the flesh progressive. + +If the fever is not regular, two pills of sulphate of quinine must be +given, each pill containing one gramme, one pill in the morning, the +other during the day, in order to prevent the fit, which usually takes +place in the evening. If the state of atony, of adynamia, comes on at +this period, _acetate of ammonia_ must be given, from one to six ounces, +in a pint of water, the same to be administered in two doses; only the +acidulous or alkaline drinks must be discontinued, otherwise the acetate +of ammonia would be decomposed in its passage into the digestive +channels. Finally, the eyes, the nostrils, and the mouth must be +frequently washed with an infusion of camomile, or some other aromatic +plant. + +The setons must be kept up very carefully. If the sick animal relishes +the nutritive beverages, let him have a decoction of bread, rice, +barley, or oats. + + +_Fourth Period, or that of Decline._ + +At this stage of the disease, in which adynamia predominates, everything +must tend to support the organism. The drinks must be bitter and +stimulating; beer, with plenty of hops in it, with an addition of +powdered Peruvian bark or sulphate of iron, may be given; or a decoction +of this bark, with gentian roots, centaury leaves, and hops; or again, a +beverage may be administered night and morning, made of veterinary +theriacum, of extract of juniper and alcohol; or finally, an infusion of +aromatic plants. + +If the diarrhoea be bloody and fetid, give the animal night and +morning a clyster, consisting of a decoction of Jesuit's bark, adding +thereto a spoonful of powdered wood charcoal, pounded to the finest +powder, and passed carefully through a sieve. If the running ceases, its +return must be excited by injecting in the nostrils a spoonful of +sternutatory vinegar or smelling salts. Finally, the purulent boils must +be opened, and dressed with stimulating ointment. + +At this closing period, which determines the fate of the disease, as we +say, there is a tendency to despair of the cure. Seeing the fatal course +of most attacks, we lose heart, death seems inevitable, and we yield its +prey to its fangs. But let us not despair; let us remember that, in +these febrile infectious diseases, above all, the phenomena must almost +always proceed to the last stage of exhaustion of the vital powers to +render the cure attainable. Some patients, smitten with typhoid fever or +cholera, have owed their lives to the indefatigable tenacity of the +contest _in extremis_ between life and death. + +I still see before me a choleraic patient, whom, during the epidemic of +1849, I had left in the morning at ten o'clock, passing into the cold +period. At five o'clock I returned to see him; the whole family was in +tears, and the sheet had been thrown over the patient's head, as if he +had already breathed his last. Time was precious to me at that fell +season, and I was about to retire, when I applied my finger to the wrist +of the sufferer, and felt a faint pulsation at long intervals. I threw +my coat off directly, called for flannel and essential oil of mustard, +which I had prescribed that morning. I set the example, and instantly +the whole family helped me to rub the patient in every direction. In a +quarter of an hour the heart quickened and revived, and in less than +half an hour more the circulation resumed its course; at the end of an +hour of this obstinate struggle the vital heat began to show itself--in +a word, the patient was saved. + +We must not, therefore, give up the contest until the death of the +sufferer is fully ascertained; and the same persistency should be +practised in the case of animals smitten with the typhus. If the +circulation slackens, if the skin turns cold, take a piece of wool, coat +it with rubefacient liniment, and rub the animal therewith, more +particularly along the spine. Then give him a cordial drink, and pass +_raies de feu_ over the loins. All these appliances will help to +stimulate the nervous system, and resuscitate the exhausted powers of +life. + +If, at last, we are so fortunate as to overcome the profound adynamia +which has utterly prostrated the frame, we next shall have to sustain +the sick animal by giving him decoctions of meat with sea-salt, or +sulphate of iron added to it, or a light broth, made with meat and +bread. + +Herbivorous animals, put upon a carnivorous diet, would not generally +endure it, of course; but some of them rather incline to unctuous +beverages, and even to cooked or raw meat. All men know that certain +horse trainers give race-horses a small portion of meat, especially when +the races are coming on, in order to increase their mettle and strength. + +We remember a sheep, which we saw at the Ecole d'Alfort, during our +studies of comparative pathology and the cutaneous diseases of domestic +animals, which manifested a great liking for meat, and even ate it +ravenously like a glutton. + +In convalescence, the animal must be sent into the open air, in some +fold enclosed with bars; he must be taken every day to pasture, each day +increasing the time he is allowed to feed, and gradually he will be left +to return to his usual regimen. But still it must be observed, that in +this distemper convalescence is long and slow, and very deceitful. A too +substantial course of feeding often revives the inflammation of the +intestines by irritating ulcerations not yet healed, and more than one +animal which had been looked upon as cured has perished in its +convalescence through a lack of watchful attention. + +Herbivorous beasts, therefore, incline to and digest animal food; +consequently, we must give sick oxen meat broths, pure milk, or milk and +water. With these must be mixed wheat straw chopped small, for hay or +even oat straw would swell and distend the stomachs. + +The typhus in this epizootia is not regular in its progress and +development. Frequently the nervous or pulmonary phenomena predominate, +when the treatment, such as we have just explained, must be modified. We +must also bear in mind that nature does not divide a disease into +periods, like those we have adopted to render our exposition of the +symptoms more intelligible and the treatment itself more methodical. + +If the nervous form of the disease prevails--if the animal shows +alternations of dulness and restlessness--if, pressure on the spine is +very painful--above all, if, in bulls, for instance, there is plethora, +let the bleedings and purgings be increased in order to abate the +nervous erethismus. In this form, the violence of the attack usually +carries off the beast. Should there, however, be any chance of saving +him it will be by employing this medication, which is at once revulsive +and depletive, notwithstanding the well-known fact that bleedings, far +from relieving the nervous system, sometimes aggravate its irritability. + +A general ablution with cold water may be tried in _desperate cases_. +The animal must then be immediately well rubbed, and covered with wool, +in order to excite a thorough reaction. + +In the pulmonary form of the typhus, but only during the acute stage, +the drinks must be warm and emollient, composed of a decoction of +soothing substances, with mallows, &c.; or one of linseed, to which must +be added some oxymel of squills and opium. The purgatives must be +non-stimulating; and emetics, freely diluted, for instance, will be +very serviceable. + +At the third and fourth period in this pulmonary form of the disease, +adopt the treatment prescribed for intestinal typhus. + +We might have greatly enlarged the list of the pharmaceutic agents, but +the richer a treatment is in remedies the poorer it is in cures. We have +made choice of the simplest and safest among all the remedies advised by +experienced men, making allowance for the difficulties inherent to the +number of animals, the mode of application, the cost, &c., always +keeping in view the life of the animal to be saved and the interest of +the cattle owners. + +We think that the treatment by inoculation might have prevented the +typhus in a very large proportion, and that the curative medication +might have saved many of the infected cattle at the worst period of the +epizootia. + +Such, then, are the results which will one day be obtained, when we +shall be able to supersede the barbarous process of general +extermination, by the adoption of a rational treatment, founded at once +on science and practical experience. + + +IV. + + _Hygienic Measures to be taken against the Extension of the + Contagion--Acts and Orders concerning Sanitary Police + Regulations._ + +I have purposely neglected, in discussing the various plans of +treatment, certain measures to be adopted with the object of opposing +the spread of the contagion. The memorandum published on this subject by +the Privy Council, and drawn up by Dr. Thudichum, is so complete and so +clear, that we can find nothing better to say. I recommend its perusal +to all who possess horned cattle, and who have occasion to send them to +any distance. It is of the highest importance to follow this judicious +advice, as the general interest will constitute here the safeguard of +the pecuniary interests of each in particular. I add to this memorandum +upon hygienic measures, the consolidated and amended acts and orders +published under the head of "Sanitary Police." In this way those +interested will have beneath their eyes all which it is important for +them to know, both in a medical and legal point of view. + + MEMORANDUM _on the Principles and Practice of + Disinfection, as applicable to the present Epidemic of + Cattle Disease_. By J. L. W. THUDICHUM, M.D. + + + [Sidenote: I.--Principles of disinfection.] + + I.--PRINCIPLES OF DISINFECTION. + + [Sidenote: 1. Definition of disinfection.] + + 1. The term disinfection signifies the removal and + destruction, or destruction and subsequent removal of the + products of destruction, of all matters actually being or + containing products of disease capable of reproducing + disease in other animals. + + [Sidenote: 2. May include special purification and + deodorization.] + + 2. If the same processes and means, as used for this + purpose, are applied to the purification and deodorization + of places and things not actually infected, but capable or + suspected of being infected, then these preventive measures + are practically and properly included under the definition + of disinfection. + + [Sidenote: 3. Reproducers and primary carriers of + infection.] + + [Sidenote: Infectious parts of dead animals.] + + 3. The reproducers of the infectious matter or contagion are + all kinds of cattle of the ox tribe, which also are at + present in this country the only animals liable to its + specific effects. It is probable that the contagion adheres + with particular pertinacity to all secretions and discharges + from sick animals. For this reason, fæces or droppings, + urine, ruminated food, all secretions from the mouth, nose, + and eyes, and any sore parts of the surface of the diseased + animals must be considered as the principal and primary + carriers of the infectious matter or plague poison. It is + also probable that many parts of animals which have died + from the cattle plague, or have been killed during advanced + stages of the disease, are infectious, some because they are + primarily imbued with the contagion, others because they + have been in contact with it after the death of the animal. + Skins, hides, hair, horns, and hoofs, must therefore always + be treated with precaution. The chances of infection by + flesh, fat, cleaned guts, and blood, are perhaps more + remote, but cannot be lost sight of. + + [Sidenote: 4. Particular danger of droppings, or fæces.] + + 4. The cattle plague, although affecting every part of the + animal, shows its visible effects most extensively in the + intestinal canal. It is believed, and apparently upon good + grounds, that the intestinal discharges are the principal + agents, upon the distribution of which mainly depends the + spread of the disorder. + + [Sidenote: 5. Enumeration of infected things and places.] + + 5. It follows from the above, that all articles which have + been in contact with a diseased animal, or any of its + discharges, particularly its fæces, are capable of carrying + the infection for an indefinite time, and must be looked + upon as being actually infectious to other healthy animals. + Such are racks of wood or iron; cribs or mangers of wood, + iron, or stone; articles used for fastening animals; leather + collars and straps, ropes and chains; all harness of any + animals used for drawing, and all carts, waggons, and + carriages which they have actually been drawing; the stalls + or sheds in which animals have been standing; the whole + lengths of the gutters and drains through which their urine + has been flowing; the entire surface over which their manure + has been drawn, and all implements with which the removal + has been effected; the entire dung-heap upon which infected + manure has been put, and the fluid contents of the manure + pit, or of the special receptacle for the urine; yards or + sheds in which cattle have been kept to tread down long + straw, and the whole of such straw and manure, as also the + ground beneath them; paths and roads upon which diseased + cattle have walked or been carried; fields and meadows upon + which they have been grazing; all carts, carriages, trucks + and railway trucks in which diseased cattle have been + conveyed, and all the platforms, railings, bridges, and + boards upon which they have been moved thereto; as also all + apparatus which has been used to pen, tie, lift, haul, + lower, and fix them; the clothes, and particularly shoes and + boots, and iron-pointed sticks of drivers and their dogs; + the apparel of all cattle-herds or attendants, particularly + their shoes and boots; the shoes and boots of all persons + visiting places where diseased cattle are or have been + standing; and, in general, the clothes of all persons + visiting infected places, ships, and all parts of the + platforms, stages, stairs and bridges, hoists and cranes + used for embarking and landing the animals; markets, and all + sheds, and pens, and implements used in contact with cattle; + slaughter-houses, and all persons and implements in them + which have been employed upon sick cattle, as also sundry + parts or organs which come from sick animals killed in + slaughter-houses; knackers' yards, trucks or carts, horses, + men, and implements which have been employed in the disposal + of sick or dead animals; wells and ponds from which diseased + cattle have been drinking, or into which any portion of + their excreta has had any opportunity of flowing, directly + or indirectly; all fodder, grass, hay, straw, clover, &c., + and particularly remnants of fodder upon which diseased + cattle have been feeding; and, in general, all persons, + animals, places, buildings, and movable things which have + been in contact with matters proceeding from diseased + cattle, or with such diseased cattle themselves. To the + above-mentioned places and things any of the processes and + agents enumerated and described in the following may have + to be applied. + + + [Sidenote: II. Practice of disinfection.] + + II.--PRACTICE OF DISINFECTION. + + [Sidenote: A. Disinfection by earth.] + + [Sidenote: 1. Burying of animals, &c.] + + A. _Disinfection by Earth._ 1. _Burying._--All matters that + can be buried, so as to remain covered with a thick layer of + ground or earth are innocuous. The ground chosen for such + interment should be dry. The quickest, and cheapest, and + most certain way of disinfecting an animal dead from the + plague is to bury it entire. + + [Sidenote: 2. Burying of dung.] + + 2. The droppings, and all straw and other matters + contaminated therewith, may also be buried into ground where + they are not likely to be disturbed for a long time. The + places from which such droppings have been removed to be + cleaned and disinfected as will be described below. + + [Sidenote: 3. Infected manure and compost heaps.] + + 3. Manure heaps and the down-trodden manure of cattle yards, + if they have become infected by even a small quantity of the + droppings of a diseased animal, should be carefully shifted + to a suitable piece of ground, and there be transformed into + compost heaps. A layer of manure one or two feet in + thickness should be covered all over with six inches of dry + earth, ashes, and mineral rubbish; upon this another layer + of manure may be placed, and then again a layer of earth, + and so forth, until the whole of the manure is stacked; it + should be covered all over with a continuous layer of earth + of from six inches to one foot in thickness. If the manure + heap or yard manure cannot be shifted, it may be covered on + the spot with a layer of dry earth, after which all animals + are to be kept away from it. + + [Sidenote: 4. Removal of boil infected by soakage.] + + 4. If the floor of any shed or stable in which diseased + cattle has been standing is not constructed with special + water-tight and impenetrable material, it must be assumed to + be infected to the depth of at least six inches. This ground + should therefore be removed, together with any stones, + pavements, or wood work which may have been in contact with + it, carted to a piece of dry land and buried. Half-rotten + wood is a particularly favourable carrier of infection. + Mortar, bricks, loam, or any other lining of the sides of a + pen in which a diseased animal has been standing, should be + broken out and buried. + + [Sidenote: B. Disinfection by fire.] + + [Sidenote: 1. Burning.] + + B. _Disinfection by Fire._ 1. _Burning._--All infected + articles of a minor value, or made of incombustible + materials, can be disinfected by exposing them to a heat + which will char organic matter. To this class of articles + may be reckoned racks of wood or iron; cribs or mangers of + wood, iron or stone; leather collars and straps, ropes and + chains; dry manure, residues of fodder from which diseased + cattle have eaten; and all such small articles of little + value which can easily be replaced by new ones. Chains may + be exposed to a dull red heat; all other articles may be + heated over a fire of coal, brushwood, or straw until well + scorched. All new articles of ironware should be bought in a + galvanised state, to prevent the formation of rust, the + accumulations of which form convenient seats for infectious + matter, and for the same purpose it is desirable that iron + articles which have been disinfected by heat as above should + afterwards be either galvanised, or, at least, while hot be + treated with resin, to cover them with a durable varnish, or + should be varnished or painted. + + [Sidenote: C. Disinfection by chloride of lime. General + remarks.] + + C. _Disinfection by Chloride of Lime._--Chloride of lime, or + bleaching powder, is the most powerful, the cheapest and + most easily managed of all artificial disinfectants. It can + be had everywhere, and at any time, and in quantities + sufficient for every purpose. It should as much as possible + he applied in solution, of a strength varying somewhat with + the particular purpose for which it is to be employed; and + after it has been allowed to act upon the surface or matter + to be disinfected a reasonable time, should be washed off, + together with all products of decomposition. As chloride of + lime does not destroy only the infectious matter in a + mixture, but destroys all organic matter without + distinction, it is not applicable to large quantities of + matter, such as the manure of cattle, dung-heaps, &c., + inasmuch as twice or three times the weight of these matters + of chloride of lime would be required for their effectual + destruction and disinfection. It is further inapplicable to + all matters rich in ammonia, particularly putrid urine, as + it destroys the ammonia and evolves a large amount of gases, + some of which have a repugnant odour, and are perhaps not + quite innocuous. But for the disinfection of surfaces of + things and places no better or more suitable agent than + chloride of lime is at present known to science. + + [Sidenote: D. Special directions for disinfection of + stables, sheds, &c., trucks, and ships, &c.] + + [Sidenote: 1. Special directions.] + + [Sidenote: Washing.] + + [Sidenote: Scrubbing.] + + [Sidenote: All washing water to be disinfected.] + + D. _Special Directions for the Disinfection of Stables, + Sheds, Vans, Railway Trucks, and Cattle Ships,[V] and of + Persons and Things connected with them._--1. After such a + place has been cleaned by mechanical means, scraping, &c., + as much as possible, and all manure and dirt has been + carefully buried, the entire surface which has been + contaminated, or is likely to have been contaminated, should + be covered with a layer of chloride of lime in powder. The + powder should be worked about with a broom until equally + distributed. It is intended to disinfect the water to be + used in the washing process which is now to commence. Clean + water, from a hose in which it flows under pressure, or from + a force-pump, garden-engine, or from large watering-pots or + water-cans, or poured freely from buckets, should now be + applied to the entire surface by one person, while another + at the same time scrubs the entire surface; and particularly + all crevices, joints, and irregularities. The washing water + and chloride of lime are then to be worked down the gutters, + into the sinks, cesses, or natural watercourses. No washing + water from any infected place or thing should ever be + allowed to flow into any cesspool, urine-hold, dung-heap, + pond, sewer, or natural watercourse, without having + previously been mixed and stirred with a liberal amount of + chloride of lime. When the place has thus been scrubbed + until the water flows off clean, it is ready for effectual + disinfection. + + [Sidenote: 2. Actual disinfection.] + + [Sidenote: Solution of chloride of lime.] + + [Sidenote: How applied.] + + [Sidenote: How long to be left on.] + + 2. For this purpose a solution of chloride of lime in water, + in the proportion of one pound of the powder to one gallon + of water, is made. For the lair of one animal from six to + ten gallons of such fluid should be prepared. This fluid is + now distributed over the whole surface to be disinfected, + gradually, by squirting from a syringe, or by pumping + through a force-pump, garden-engine, or by watering from a + watering-pot or can with a finely pierced rose. All + woodwork, stones, bricks, cement, mortar, all fixtures of + whatever material, should be well wetted with the solution, + and immediately be scrubbed with a hard brush. Floor and + ceiling are also scrubbed, and the whole is left in this wet + state covered with the chloride of lime solution for at + least one hour, during which time care is taken that no + parts become dry. + + [Sidenote: 3. To be washed off after disinfection.] + + [Sidenote: Flushing.] + + [Sidenote: Precautions as to direction of clean water.] + + 3. As the chloride of lime and the products of its + decomposing action upon infectious matters may be hurtful to + cattle, these matters have to be carefully washed off by a + second and final flushing. For this too much water and too + much scrubbing cannot be employed. Care should be taken to + apply the clean water always to the highest parts, so as to + cause it to flow thence to the lower parts, and to wash away + the waste from the lower parts before applying any fresh + water to the upper parts. + + [Sidenote: 4. Care not to carry back dirt by brooms, boots, + &c.] + + 4. Care should also be taken to rinse and flush every broom + which has worked away sediment and waste from the lower + parts into and through the gutters and drains before + applying it again to the clean upper parts. Care should also + be taken that the working persons should not step from the + dirty or partially cleansed places on to the clean ones, as + this may suffice to bring infection back to the disinfected + place. + + [Sidenote: 5. Disinfection of workmen and tools.] + + 5. Lastly, all persons employed in this work, having swept + and flushed the gutters with the same care as the lairs, are + collected, together with all engines and tools which they + have used, as near as possible to the sink or place of final + egress of water from the premises, and there disinfected as + will be described. + + [Sidenote: Tools.] + + The tools, such as hooks, forks, spades, hoes, barrows, &c., + are scrubbed with the above solution of chloride of lime, + and subsequently water until clean; they are then + repeatedly wetted with the solution, and after it has had + time to disinfect the entire surfaces of them, they are + washed clean and laid up, or hung up to dry. + + [Sidenote: Workmen.] + + [Sidenote: Disinfection of boots.] + + [Sidenote: Disinfection of workpeople's bodies, hands, &c.] + + [Sidenote: Changing and disinfecting clothes.] + + [Sidenote: Burning of articles of little value.] + + The workmen, then, having finished the disinfection and + flushing of all objects and surfaces, effect their own + disinfection in the following manner:--They wash their boots + most carefully with chloride of lime and water, scraping the + soles and scrubbing the seams where the soles join the upper + leather. They wash their hands and arms, and by means of + clean rags or sponges they remove any splashes from their + clothes. After this they go indoors, remove all clothes from + head to foot, wash their bodies, and particularly their + hands, faces, hair and feet, with plenty of soap and water, + and put on fresh clothes and linen. The clothes and linen + which they have taken off should be treated as infected, set + to soak immediately in boiling water and afterwards + disinfected, or in water containing two ounces of chloride + of lime to the gallon in solution, or containing four ounces + of Condy's red permanganate of potash fluid in solution; or + the clothes and linen should be put in a copper and boiled + and subsequently washed. All articles of little value which + are much soiled should be burned on a bright fire. + + [Sidenote: E. Disinfection of live stock.] + + [Sidenote: 1. Stock may carry infection in two modes.] + + E. _Disinfection of Live Stock._--1. Live cattle may carry + infection in two ways: first, by being themselves infected + with the plague and reproducing the poison; and secondly, by + accidentally carrying the poison from other animals in a + dormant state upon some part of their surface, their hair, + and particularly their feet. These latter animals may + therefore infect others without being or becoming themselves + subjects of the plague. All persons therefore buying new + animals, should disinfect them before allowing them to enter + their premises. In a similar manner, if in a stable there + has been a case of plague, the healthy or apparently healthy + animals should all be disinfected. + + [Sidenote: 2. Mode and means of disinfecting live stock.] + + [Sidenote: Warming and refreshing drink.] + + [Sidenote: Penned in the quarantine shed.] + + 2. The mode in which live animals may be disinfected, + consists in washing them with disinfectant solutions of such + strength as will destroy the contagion without injuring the + surface of the animal. A solution of two ounces of chloride + of lime in a gallon of water, is a proper solution for + washing the coat of animals. A mixture of four ounces of + Condy's red permanganate of potash fluid, with one gallon of + water, is also a proper disinfectant solution. For + full-sized cows and bullocks, &c., several gallons of either + of these solutions should be used. Great care should be + taken to keep the solution away from the eyes, nostrils, + mouth, and tender parts. When the entire surface is washed + and disinfected, all disinfectant is removed by the + application of great quantities of clean tepid water to all + parts. The animal is given a warming and refreshing drink, + and is conducted by a clean attendant to the clean + quarantine shed. There it should receive fodder both dry and + green, and sop, and plenty of pure cold water, and be rubbed + dry with whisks of straw and hay. + + [Sidenote: F. The quarantine shed.] + + [Sidenote: 1. Objects.] + + [Sidenote: Both quarantine and surface disinfection are + required.] + + F. _The Quarantine Shed._--1. The quarantine shed is + intended to keep the new and suspected cattle separate for a + period of at least ten days, in order to afford the + security, to be obtained by observation alone, that it is + not actually infected with plague. While, therefore, + disinfection of the surface of cattle removes one kind of + danger, another, which cannot be removed, can only be kept + circumscribed or penned in, and this is done by the + quarantine shed. But the keeping of cattle in the quarantine + shed would not disinfect its surface with certainty even + during a much longer period than ten days; disinfection of + the surface therefore cannot supply the precaution of the + quarantine shed, and a rigorous quarantine cannot supply the + effect of surface disinfection. Both precautions are + necessary for perfect security, although either of them, + without the other, obviates a particular kind and a certain + amount of danger. + + [Sidenote: 2. Management of the quarantine shed.] + + 2. The quarantine shed should be situated in an isolated + part of the premises. All manure and urine from it should + flow and be carried to a particular place separate and + distinct from the common dung-heap, and be buried daily. + + [Sidenote: Cleanliness.] + + [Sidenote: Persons attending healthy stock not to attend + quarantine shed, and vice versâ.] + + The utmost cleanliness should be observed in the shed. All + tools, pails, currycombs, etc., used in this shed should be + used in it exclusively and nowhere else. The person + attending the quarantine shed should not be allowed to go + into the shed where healthy stock is kept, or permitted to + approach healthy stock. No person attending healthy stock + should be permitted to approach quarantine cattle, or to go + near or into the quarantine shed. But should unfortunately + only one person be available for both duties, that person + should be allowed to approach quarantine cattle only when + clothed in the safety dress to be immediately described. + + [Sidenote: G. The safety dress.] + + [Sidenote: 1. Description.] + + G. _The Safety Dress._--1. This consists of strong + water-boots reaching up to the knees, well greased all over; + of a waterproof coat, buttoned close all the way up in + front, and closing tightly round the neck and wrists. The + head is to be covered with a cap which takes the hair well + in. + + [Sidenote: 2. Persons who should use the safety dress.] + + [Sidenote: To disinfect before leaving suspected or infected + premises.] + + 2. Every person having occasion to visit sheds in which + there is diseased cattle, or suspected cattle, or quarantine + cattle, should be provided with the above dress, put it on + when entering the place, take it off when leaving the place, + and have it disinfected immediately. This precaution should + be strictly observed by all inspectors, all veterinarians, + or others called in to attend sick cattle, by all dealers + and butchers entering sheds, yards, or meadows, for the + purpose of sale or purchase, and by all other persons coming + on the premises on business in connexion with cattle. + + [Sidenote: 3. Strangers not to enter sheds except in + disinfected safety dresses.] + + [Sidenote: Proprietors of cattle to keep safety dresses.] + + 3. The owners of stock should not allow any strangers to + enter their sheds, yards, or meadows, except in disinfected + safety-dresses; and in case this should give rise to + difficulties, they will do well to have themselves one or + two such safety-dresses at hand, and to cause all persons + whose business compels them to enter their sheds, to leave + their own boots behind, and to put on the long boots, + waterproof-coat, and special cap. Only thus can they hope to + exclude all ordinary and obvious chances of infection from + their previously healthy sheds, yards, and meadows. + + [Sidenote: H. Measures to be taken where plague has + appeared.] + + [Sidenote: Killing and burying diseased animals.] + + [Sidenote: Disinfecting the living and the stables.] + + H. _Measures to be taken on Premises where Plague has + actually appeared._--1. When the plague has actually + appeared in any shed, yard, or place, the sick animal should + at once be removed with all due precautions. It is certainly + the safest and best to pole-axe the animal at once, and to + bury it entire, and then to disinfect the particular lair as + above described, clear out the stable or shed, disinfect + the whole of it and all apparatus, also all the animals, and + only to let the animals enter the shed, &c. again, after it + is completely sweet and dry. + + [Sidenote: 2. Hospital shed.] + + [Sidenote: Situation of.] + + 2. If, however, a proprietor is desirous of keeping a sick + animal because its illness does not appear severe or fatal, + he should place it in a separate shed, which must not be the + same as or near to the quarantine shed, and be distant from + all healthy animals, and so situated that the prevailing + wind does not blow from this hospital shed towards the + healthy or quarantine shed. The water should also not flow + from this hospital shed towards the others, or the yard, or + any meadow, but should be carefully drained away and sent + off the premises by a special sink. + + [Sidenote: 3. Preventing of diffusion of fæces.] + + 3. To prevent the scattering of fæces by infected animals + (and also by suspected animals and all animals suffering + from diarrhoea), their tails should be so tied to one or + other of their horns as to protect them against being soiled + by the intestinal discharges, and to prevent them from + distributing such discharges by the ceaseless motions + peculiar to these organs. The spattering of fæces should be + prevented by a copious supply of rough straw, with some + sand, sawdust, or ashes placed behind and underneath the + animal. The straw and fæces should be dealt with as has been + described. Animals affected with plague or diarrhoea should + not be led along streets, highroads, and paths, as they + would be certain to drop infectious fæces, which would then + be distributed over the entire length of these roads by the + feet of men and animals, and the wheels of vehicles. + + [Sidenote: 4. Special management of hospital shed.] + + [Sidenote: Persons to be employed.] + + 4. The sick animals should be disinfected repeatedly; their + pens should be cleaned and disinfected repeatedly, during + the course of the illness. This should be done by persons + either guarded by the safety dress, or--and this is + safest--by such as may not come into contact with healthy + cattle, or have to enter healthy sheds. All tools, pails, + fodder, &c., to be used in the hospital shed to be kept for + that purpose only, and never to be used with healthy, or + quarantine, or only suspected cattle. + + [Sidenote: 5. Disinfection of parts of dead or killed + animals.] + + 5. If the proprietor of any dead piece of cattle, whether it + has died naturally or been killed, should decide upon + dismembering it instead of burying it entire, and upon + utilising the hide, horns, hoofs, tallow, and bones, he + should disinfect the skin, horns, and hoofs, by steeping + them for one hour in a strong solution of chloride of lime, + containing one pound of the powder in each gallon of water, + and afterwards washing them. The tallow should be thickly + powdered with chloride of lime all over, and be sent + directly to the boilers. It should not be boiled in any + vessel employed on the farm. Under all circumstances, it is + advisable to let this dismemberment of dead and fallen + cattle he performed at the knacker's yard. + + [Sidenote: 6. Flesh, &c., to be buried.] + + 6. Flesh, blood, guts, lungs, and the bones of the head of + infected animals should not be trafficked with, as they + cannot easily be disinfected. They should always be buried. + + [Sidenote: I. Disinfection of meadows, fields, roads, &c.] + + [Sidenote: 1. Meadows.] + + I. _Disinfection of Meadows, Fields, Roads, &c._--1. Meadows + infected by diseased cattle should be carefully cleaned of + all dung, by burying each dropping on the spot where it + lies, cutting out the round piece of turf with the dropping + on it, and turning it upside down. The grass on the entire + meadow should then be cut and burned. It should then be left + without any cattle for at least a month, including at least + two wet days. + + [Sidenote: 2. Of roads, &c.] + + 2. All roads, paths, streets of towns, or villages should be + carefully and frequently scavenged. All carts, vans, or + waggons used for carrying manure, should be water-tight, + caulked and painted, and should not be permitted to ooze and + drop their fluid or semi-fluid contents on the road over + which they are drawn. They should be kept clean and + disinfected, as a precautionary measure, by the proceedings + above described. + + + [Sidenote: III. General recommendations.] + + III. GENERAL RECOMMENDATIONS. + + In conclusion it must be pointed out to farmers, dairymen, + and all persons having charge of cattle, + + _That the same great measures which are known to maintain + and restore the health of human beings, will also maintain + and restore the health of cattle._ + + Pure air; dry, spacious, well-ventilated and well-drained + clean sheds; clean and dry meadows; plenty of pure water; + frequent currying and washing; the prevention of the + development, by the destruction of the germs, of internal + and external parasites, particularly entozoa; proper food in + suitable quantities, and at proper times; protection from + inclement weather; the utmost cleanliness in the removal of + manure; the storing of the manure at a great distance from + the cattle-shed, and, in addition, the most conscientious + observance of the precautionary and disinfecting measures + above described--all these measures and agents together + will secure the utmost possible health of stock and the + prosperity of the agriculturist and dairyman. But the + neglect of any one of them will make the stock liable to + become infected, and the more so the more several or all + collateral conditions of the healthy existence of animals + are neglected. The negligent man is therefore certain to + lose, to injure his neighbour by defeating his precautions, + and to damage society; but the watchful and painstaking man + will be rewarded not only by the preservation of his + property, but particularly by the consciousness that it has + been preserved by his own care and attention, and that + thereby he has also benefited the state. + + * * * * * + +This consolidates and amends the former Orders. + + (_Copy._) + + At the _Council Chamber, Whitehall_, the 22nd day of + _September_, 1865. + + By the Lords of Her Majesty's Most Honourable Privy Council. + + PRESENT. + + Lord President. + Duke of Somerset. + Earl of Clarendon. + Earl de Grey and Ripon. + Mr. Secretary Cardwell. + Mr. H. A. Bruce. + + WHEREAS by an Act passed in the session of the eleventh and + twelfth years of Her present Majesty's reign, chapter one + hundred and seven, intituled "An Act to prevent until the + 1st day of September, 1850, and to the end of the then next + session of Parliament, the spreading of contagious or + infectious disorders amongst sheep, cattle, and other + animals," and which has since been from time to time + continued by divers subsequent Acts, and lastly by an Act + passed in the session of the twenty-eighth and twenty-ninth + years of the reign of Her present Majesty, chapter one + hundred and nineteen, it is (amongst other things) enacted + that it shall be lawful for the Lords and others of Her + Majesty's Privy Council, or any two or more of them, from + time to time, to make such Orders and Regulations as to them + may seem necessary for the purpose of prohibiting or + regulating the removal to or from such parts or places as + they may designate in such Order or Orders, of sheep, + cattle, horses, swine, or other animals, or of meat, skins, + hides, horns, hoofs, or other part of any animals, or of + hay, straw, fodder, or other articles likely to propagate + infection; and also for the purpose of purifying any yard, + stable, outhouse, or other place, or any waggons, carts, + carriages, or other vehicles; and also for the purpose of + directing how any animals dying in a diseased state, or any + animals, parts of animals, or other things seized under the + provisions of the said Act, are to be disposed of; and also + for the purpose of causing notices to be given of the + appearance of any disorder among sheep, cattle, or other + animals, and to make any other Orders or Regulations for the + purpose of giving effect to the provisions of the said Act, + and again to revoke, alter, or vary any such Orders or + Regulations; and that all provisions for any of the purposes + aforesaid in any such Order or Orders contained shall have + the like force and effect as if the same had been inserted + in the said Act; and that all persons offending against the + said Act shall for each and every offence forfeit and pay + any sum not exceeding twenty pounds, or such smaller sum as + the said Lords or others of Her Majesty's Privy Council may + in any case by such Order direct:-- + + And whereas a contagious or infectious disorder now prevails + among the cattle of Great Britain, which is generally + designated the "cattle plague," and may be recognised by the + following symptoms:-- + + "Great depression of the vital powers, frequent shivering, + staggering gait, cold extremities, quick and short + breathing, drooping head, reddened eyes, with a discharge + from them, and also from the nostrils, of a mucous nature; + raw-looking places on the inner side of the lips and roof of + the mouth, diarrhoea or dysenteric purging:" + + And whereas several Orders, dated respectively the 24th of + July, the 11th, 18th, and 26th of August, 1865, have been + made under the authority of the said Acts by the Lords of + Her Majesty's Privy Council, with a view to check the + spreading of the said disorder: + + And whereas it is expedient to consolidate and amend the + said Orders: + + Now, therefore, the Lords of Her Majesty's Privy Council do + hereby, by virtue of, and in exercise of the powers given + by, the said Act, so continued as aforesaid, order as + follows:-- + + 1. This Order shall extend to all parts of Great Britain. + + 2. The said Orders dated respectively the 24th of July, the + 11th, 18th, and 26th of August, 1865, are revoked, with the + exception of so much of the said Order of the 24th of July, + 1865, as empowers the Clerk of Her Majesty's Privy Council + to appoint Inspectors within the limits of the Metropolitan + Police District, provided that such revocation shall not + affect any appointment made, or any act done, or penalty + recoverable, under any Order hereby revoked. + + 3. In this Order the word "animal" shall mean any cow, + heifer, bull, bullock, ox, calf, sheep, lamb, goat, or + swine; and the word "Inspector" shall include any Inspector + appointed under this Order, or under any of the said revoked + Orders. + + 4. Whenever the Local Authority, as hereinafter defined, + shall be satisfied of the existence of the said disorder in, + or have reason to apprehend its approach to, the district + over which his or their jurisdiction extends, it shall be + lawful for such Local Authority, if he or they shall think + fit, from time to time to appoint one or more Veterinary + Surgeon or Surgeons, or other duly qualified person or + persons, to be an Inspector or Inspectors, for the purpose + of carrying into effect the rules and regulations made by + this Order, within the district for which he or they shall + have been appointed. And the same authority may, from time + to time, revoke such appointment. + + 5. Subject to the powers herein reserved to the Clerk of Her + Majesty's Privy Council, the Local Authority within the City + of London, and the liberties thereof, shall be the Lord + Mayor; in any municipal borough in England or Wales, the + Mayor; in any Petty Sessional Division in England or Wales + (exclusive so far as relates to the jurisdiction of the + Inspector of so much of the said division as lies, within + the limits of a municipal borough for which an Inspector has + been appointed), the Justices acting in and for such Petty + Sessional Division. The Local Authority in any burgh or town + in Scotland which is subject to the jurisdiction of a + Provost or other Principal Magistrate, shall be the Provost + or such Principal Magistrate; and in any other place in + Scotland not within the jurisdiction of such Provost or + other Principal Magistrate, the Justices of the County in + Sessions assembled. + + 6. Every Inspector shall from time to time report to the + Local Authority by which he is appointed, the steps taken by + him for carrying into effect the regulations prescribed by + this Order; and the Local Authority shall certify, in such + manner as may be directed by one of Her Majesty's Principal + Secretaries of State, the number of days that such Inspector + has actually been engaged in the performance of his duty, + and the number of miles travelled by him while thus engaged. + + 7. Every Inspector shall furnish the Lords of the Council + with such information in regard to the said disorder, as + their Lordships may, from time to time, require. + + 8. Every person having in his possession, or under his + custody, any animal labouring under the said disorder, shall + forthwith give notice thereof to the Inspector of the + district within which such person resides, or if no + Inspector shall have been appointed for the district within + which such person resides, then to the Officers hereinafter + named, according to the place of residence of the person + obliged to give notice; that is to say: within the + Metropolitan Police District, to the said Clerk of the Privy + Council; within the City of London, and the liberties + thereof, to the Lord Mayor; within any other borough, burgh, + or town subject to the jurisdiction of a Mayor, Provost, or + other Principal Magistrate, to such Mayor, Provost, or other + Principal Magistrate; elsewhere in England, to the Clerk of + the Justices acting in and for the Petty Sessional Division; + and elsewhere in Scotland, to the Clerk of the Peace of the + county. + + 9. Every Inspector shalt have power to enter upon and + inspect any premises or place in which any animal or animals + may be found within the district for which he is appointed, + and to examine and inspect, whenever and wherever he may + deem it necessary, any animal within such district. + + 10. Every Inspector shall have power within his district to + seize and slaughter, or cause to be seized and slaughtered, + and to be buried, as hereinafter directed, in any convenient + place, any animal labouring under the said disorder. + + 11. Every Inspector shall have power within his district to + cause to be cleansed and disinfected, in any manner which he + may think proper, any premises in which animals labouring + under the said disorder have been, or may be, and to cause + to be disinfected, and if necessary destroyed, any fodder, + manure, or refuse matter, which he may deem likely to + propagate the said disorder. And every owner or occupier of + such premises shall obey any order given by such Inspector + for that purpose. + + 12. Every Inspector shall have power within his district to + direct that any animal which he suspects to be labouring + under the said disorder, shall be kept separate from animals + free from the said disorder. And every person having in his + possession, or under his custody, such animal, shall obey + any order given by such Inspector for that purpose. + + 13. Every person having in his possession, or under his + custody, any animal labouring under the said disorder, + shall, as far as practicable, keep such animal separate from + all other animals, and shall not, if the animal be within a + district for which an Inspector has been appointed, remove + the same from his land or premises, without the licence of + the Inspector. + + 14. No person shall send or bring to any fair or market, or + expose for sale, or send or carry by any railway, or by any + ship or vessel coastwise, or place upon, or drive along, any + highway or the sides thereof; any animal labouring under the + said disorder. + + 15. No person in any district for which an Inspector has + been appointed shall, without the licence of the Inspector, + send or bring to or from market, or remove from his land or + premises, any animal which has been in the same shed or + stable, or has been in the same herd or flock, or has been + in contact, with any animal labouring under the said + disorder. + + 16. No person shall place, or keep, any animal labouring + under the said disorder in any common or unenclosed land, + or, if the animal be in a district for which an Inspector + has been appointed, in any field or pasture, where, in the + judgment of the Inspector, such animal may be likely to + propagate the said disorder. + + 17. All animals having died of the said disorder, or having + been slaughtered on account thereof; shall be buried with + their skins, and with a sufficient quantity of quick-lime, + or other disinfectant, as soon as practicable, and shall be + covered with at least five feet of earth, or shall, in + districts for which an Inspector has been appointed, with + the consent of the owner, be otherwise disposed of; in + manner directed by the Inspector. + + 18. During the continuance of the "cattle plague" within + the said City of London, or that part of the Metropolitan + Police District which is under the jurisdiction of the + Metropolitan Board of Works, no animal shall be brought or + sent to the Metropolitan Cattle Market, or any other market + within the said City or the said part of the Metropolitan + Police District, except for the purpose of being there sold + for immediate slaughtering; and every such animal, as soon + as sold, shall be marked for slaughter, in the manner in + which cattle are ordinarily marked for slaughter in the + Metropolitan Cattle Market. + + 19. Whenever any Local Authority, as hereinbefore defined, + declares, by notice published in any newspaper circulating + within his or their jurisdiction, that it is expedient that + animals, as hereinbefore defined, or some specified + description thereof, shall be excluded from any specified + market or fair within that jurisdiction, for a time to be + specified in such notice, it is hereby ordered, that after + the publication of such notice, it shall not be lawful for + any person to bring or send such animals or description + thereof into such market or fair: provided always, that this + clause of this Order shall not, unless renewed by a further + Order, be in force after the expiration of three calendar + months from the date of this Order. + + 20. Every person offending against this Order shall, in + pursuance of the said Act, for every such offence forfeit + any sum not exceeding twenty pounds which the Justices + before whom he or she shall be convicted of such offence may + think fit to impose. + + (Signed) ARTHUR HELPS. + +FOOTNOTES: + +[R] Since these lines were put into the printer's hands, the French +Government have proposed to other nations to take measures collectively +to prevent the pilgrimage to Mecca continuing to be a cause of the +spread of cholera. We hasten to render justice to this prudent +initiative. But why not take the same measures against typhus which are +judged necessary against cholera? + +[S] The typhus which broke out fifteen days ago near Roubaix, in France, +bordering upon Belgium, where the epizootia rages, appears to have been +stifled in its focus by the instantaneous extermination of the whole +herd in which it declared itself. + +[T] "It is amusing to read authors of the last century on the treatment +of this disease. They were far more confident in their powers than we +helpless creatures pretend to be. The directions given are full and +distinct, and in chapters boldly headed 'The Cure.' The beast is to be +bled, washed, and hot vinegar and water, with aromatic herbs, may be +placed in the stable to revive the cattle. The animal must be rubbed a +quarter of an hour, both morning and evening, and the bags of a milch +cow should be anointed morning and evening with warm oil. A rowel is to +be made in the dewlap by taking a skein of hemp, tow, or twisted +packthread, a foot long, and as thick as a man's thumb. _The +prescriptions are most amusing._ They may serve to entertain those who +want the cure at present, and for this reason I reproduce one or +two."--_Gamgee, Letter on 21st August._ + +[U] Dr. Letheby reported that 12,916 lbs., or more than five tons of +meat, had been condemned in the City markets during the past week as +unfit for human food. It consisted of 64 sheep, 4 calves, 7 pigs, 142 +quarters of beef, and 361 joints and pieces of meat; 5377 lbs. were +diseased or from animals that had died of disease, and the rest was +putrid. All of it was destroyed. Yesterday, a sub-committee of the +Metropolitan Plague Committee, at a meeting at the Mansion House, passed +an unanimous resolution, on the motion of Mr. Brewster, recommending +that, as unexpected and insuperable difficulties had arisen in carrying +out the purposes for which they were appointed, the money already +subscribed should be returned to the subscribers, after deducting, _pro +ratâ_, the expenses already incurred. + +[V] For the disinfection of railway trucks and cattle ships, see Special +Memorandum. + + + + +THIRD PART. + +_To Farmers and Graziers._ + + +You would have had just cause to reproach me with a want of common sense +if I had obliged you to read a book of two hundred pages, and to lose +your time in looking for the advice you will require, if the cattle +plague should visit your stalls and herds, instead of being able to turn +at once to the matter which concerns you. I have taken up my pen on +purpose to be of service to you; this is my principal duty, which I am +now going to fulfil by summing up in a few pages the most important +facts which have been described in the two first parts of this work. + +The cattle plague, which has lately fallen upon horned beasts, is a +plague, no doubt: but there are different species of plagues, and it is +necessary that you should know that this disease is one arising from +the absorption of seeds and germs with which the air is impregnated, and +which is drawn by the animals into their bodies when breathing the air +around them. When these germs, these infectious poisons, have penetrated +into the lungs and blood of the animals, these seeds of infection remain +there from eight to twelve days without producing any very perceptible +effects; but after that time the tainted animal becomes dejected, loses +his appetite, is seized with fever, laborious breathing, and +diarrhoea, to which sum of disorders in the health of oxen, cows, &c., +the name of _typhus_ has been given; or, as this distemper is contagious +in the highest degree, it has also been called the _contagious typhus_. + +You may compare this disease, in order to form a more precise idea of +it, to the small-pox, which sometimes afflicts your children, or to +typhoid fever. These complaints, which are familiar to most of you, have +some resemblance to the typhus of the ox. Only in the small-pox, which +is caught by contagion, and which seldom attacks more than once, like +typhus, the disease is localized on the skin; whilst in the cattle +plague the internal organs are the principal seat of the evil. + +This comparison will show you at once that the cattle plague, or rather +the cattle typhus, can only be cured when the disease has run its full +course, as you have observed in a person tainted with small-pox; so that +your task must be to help the sick animal to endure his complaint until +the end, or until he is cured; and you must not attempt to check it by +violent means, for if you did you would hasten the death which you +desire to prevent. You will likewise understand that if the disease--as +is certainly the case--does not attack the same animal twice, it would +be very beneficial to inoculate the animal whilst he is sound and +healthy, whenever this scourge threatens--as in the present time--to +attack all cattle. Perhaps you may be told that inoculation, which +prevents small-pox in man, cannot be applicable to cattle; that animals +inoculated with the virus of the typhus have all died of the +consequences of the operation, and so on. To all these objections you +will answer, with that downright good sense which belongs to your class, +_that Nature cannot have two weights and two measures_; and that if the +inoculation of the typhus kills animals, whilst the inoculation of the +small-pox saves men, both maladies being governed by the same laws, it +is the inexperience of physicians, and not the operation itself, which +must be made to account for it. + +In a word, to sow virus is to reap it; but there are many ways of sowing +it, and one man will reap a rich harvest, whilst another shall gather +nothing but tares. Let those unbelievers say what they like, and take my +word for it, that we shall one day cure typhus as frequently as we do +small-pox, by inoculating it, and when it appears in spite of that +course, by treating it medicinally. + +This contagious disease is very frequent in certain countries, +principally in Russia and Hungary, on the banks of the great rivers +which empty themselves into the Black Sea. In those remote countries, +when the seasons are either too rainy or too hot--and you know what a +summer that of 1865 has been--the pastures generate the pestilential +poisons of the typhus, the cattle absorb these destructive principles, +and die of them. + +But as the herds of cattle in those countries are bred for sale, and are +sent for that purpose to other countries, to France, Italy, England, +&c., the animals which have had the germ of the disease transport it +with them wherever they go. Thus, it is certain that some oxen conveyed +from Russia and Hungary, where the typhus frequently rages, brought the +disease with them into Great Britain in the month of last June; and as +the complaint is communicated from one animal to another, and afterwards +at great distances, it spread with great rapidity over England and +Scotland. So great are its powers of contagion, that some of the cattle +sent back from England have transmitted the disease to Holland, in the +first place, and afterwards to Belgium; and it was feared at one time +that all Europe would be invaded by it. + +The first belief was--and everything tends to make good the +opinion--that the typhus originally came from abroad; but many +respectable authorities, seeing the foul and nauseous state of the +stalls and cowsheds both in London and elsewhere, the overcrowding of +the animals, and the general neglect to which they are exposed, have +asserted that the disease had its origin in London. This, we repeat, is +not likely to have been the case, but it is not absolutely impossible; +at all events, there can be no question that the grievous conditions in +which some of your brethren keep their cattle have contributed to spread +the distemper, independently of other causes. + +Moreover, it is necessary to tell you, that sheep and horned cattle are +of all living animals those which are most sensitive to the influence of +contagious diseases. Every year you see instances of this fact in your +own fields and meadows. Your sheep, you all know, easily contract the +small-pox, worm diseases both on the skin and in the interior of the +body; your oxen have aphthous diseases, disorders of the blood and the +lungs, scabs and carbuncles--diseases which are all more or less +contagious, and which are generally brought on by want of care, and, +above all, by improper feeding: by which you see how much of the +sufferings of the cattle, and of the heavy losses to you which follow +them, depends upon yourselves and may be avoided. Besides, these poor +creatures, which some of you treat so harshly, are extremely +susceptible, and the blows they receive may easily affect their whole +mass of blood. You must, therefore, for your own sakes, treat them more +kindly and gently. + +Therefore, the typhus which was imported from Russia into England, +finding your cattle in such wretched conditions of cleanliness and +health, was propagated amongst them with fearful rapidity. When once the +disease had developed itself within your sheds and stalls, it would have +been the wisest plan immediately to kill the sick cattle, or to treat +them medicinally, carefully abstaining from driving to market any of +your beasts which had been exposed to the contagion. But unfortunately +you did not act in this manner; many amongst you could not put up +patiently with your losses, and only consulting your private interest, +to the detriment of the general good, you sold your sick cows and oxen, +and sowing the contagion about the country and through the markets, the +scourge was soon scattered in every direction, so that instead of +stifling the disease at its birth everything was done to propagate and +diffuse it. + +Now, if we add, that the germs of this typhus penetrate everywhere, that +it is sufficient to convey sick cattle along the public roads, and by +this means to pass near farms and meadows containing healthy cattle, to +transmit the contagion, that these noxious germs impregnate your own +clothes, the fleece of sheep, and every article, implement, and vehicle +used in agriculture, you cannot but see how often, though unwillingly, +you must have disseminated the evil far and wide. + +The germs, the miasmata of the disease, insinuate themselves not only +upon animals and men, but they shed their virus upon the grass of the +fields, the walls of the stalls and stables, and every agricultural +utensil. Every tainted animal scatters the pestilential and contagious +germs, not only by the air he expires, but by his droppings, and after +death by his mortal remains--his hide, his horns, his entrails, his +flesh--all of which disseminate the deadly germs into the atmosphere, +which afterwards diffuses them in every direction. + +The germs of this virulent distemper have no doubt smitten some cattle +which appeared in the best health and conditions, those of the rich as +well as those of the poor; but, just in the same manner as the cholera +chiefly fixes itself upon the sickly, the ill-fed, the unclean, upon +those who live in crowded dwellings and badly ventilated rooms; so, too, +does the typhus choose its victims among the stalls and stables of those +graziers who keep their cows tied up for years to the rack, giving them +neither air nor exercise, and feeding them, not on that diet which their +health requires, but on those things which add to their milk and +increase their flesh. It follows, of course, that the greater number of +these cows, more or less disordered by this long course of baleful +treatment, and many of which die of consumption, after their +deteriorated milk has infused into men the seeds of diseases, must +afford an easy prey to the typhus, _to receive which they seem almost +expressly to have been trained_. + +It is highly important then, farmers and graziers, that you should be +able to recognise this ox-typhus; in the first place, that you may take +the necessary measures to prevent its contagion; and secondly, that you +may apply the treatment which shall have been recommended to you. + +You must at all times, but above all when the contagious disease is +raging, keep a watchful eye on your cattle. If you notice in their gait, +in their looks, about their ears, any unusual signs; if they seem to you +less eager, less active, less vigilant, if they leave any part of their +rations when in the stables, or if, when in the fields, they no longer +browse with that continual alacrity which sometimes it is difficult to +divert them from, be upon your guard, and dread the outbreak of the +complaint. If to these changes of minor importance is added an appetite +really less acute, if the rumination is less regular, if the animal +looks sad and dispirited, if he exhibits an unwonted look of gloom, if +his leaden eye continues fixed, astonished, be sure a morbid change is +inwardly at work, and that this cruel distemper is spreading through his +frame. + +By-and-bye the animal loses his appetite more and more; rumination is +shorter and less frequent; he holds his head down, his ears sink and +fall; he grinds his teeth. Then as to the cows: their milk, which was +already diminished, suddenly dries up altogether, and that lowness of +spirits which had been visible for some days before, passes into stupor. +If at this time you touch their horns, their extremities, their hide in +any part, you find that all these different parts are sometimes warm, +sometimes cold. From this day forward you will witness, one by one, a +succession of disorders in the animal's health: partial shiverings at +the attachment of the fore and hind limbs, loud panting breathing, with +slight cough, the urine scanty and thick, the droppings hard and +constipated, and finally, general excessive warmth. If you press the +back the pressure will be painful, and all the signs of intense fever +will be manifest. + +Already these indications have divulged the nature of the malady you +have to deal with; but others more significant succeed them which remove +every doubt. The breathing becomes more hurried and oppressed, more +puffy; from the eyes, nostrils, and mouth there issues a discharge +which, thin and irritant at first, soon becomes thick and purulent, and +of a fetid smell. Diarrhoea takes the place of constipation; the +sexual organs of the cow are red and inflamed, and furrowed with livid +streaks. The cattle grow leaner and leaner, some of them dying at this +period. If they still hold out, the diarrhoea becomes more frequent, +more fetid, and sometimes bloody; gases are developed under the skin, +along the spine, where they form wide flat tumours, which crackle when +pressed upon with the fingers. Finally, the mucus which runs from the +head becomes still thicker and more fetid; a glutinous foam stops up the +mouth; the eyes, filled with humour, sink in the orbit; the bodily +warmth decreases, the animal sways his head from right to left, becomes +insensible, cold; his head lolls on one side, and he dies, panting, from +exhaustion and asphyxia, the tenth or twelfth day after the disease has +been confirmed. + +The carcass exhibits a repulsive appearance; the hide is dry, +excoriated, and cracked; it sticks to the bones, which show the form of +a skeleton, and the putrid decomposition, which had already set in +before death, seizes rapidly on all the tissues. + +The course of the disease is not always the same. Sometimes the animal +is agitated at first, and all the functions of life are so disturbed +that death comes on in the two or three first days. At other times, the +lungs are more affected than the other internal organs; the cough is +more intense, the breath hurried and obstructed, the excess of mucus +preventing the air from passing into the chest. + +When once you have seen this disease it is impossible to mistake it for +any other, unless it be the chest complaint called peripneumonia, which +is likewise contagious. But in this disease, as the Report of the Royal +Agricultural Society states, the attack is generally insidious; the eyes +preserve their vivacity, and the appetite is not lost until towards the +close. A short, dry cough shows itself from the outbreak, and persists. +The breathing is frequent and painful; the sides of the chest when +struck with the fingers give out the hard, solid sound of a full barrel, +this percussion being painful. The eyes, nose, and mouth do not +discharge those purulent secretions seen in typhus; the diarrhoea only +comes on at the end, being less frequent and fetid. In the milch cows +the milk decreases, but is not quite suppressed. The heat of the horns +and lower extremities is retained. The peripneumonia, in a word, runs +its course more regularly, and carries off the animal about the fourth +week. Thus it will be seen that the two distempers widely differ in +their symptoms. + +Every beast which dies of the contagious typhus, bears on its digestive +organs the traces of the malady, more or less strongly marked. The third +and fourth stomachs and the intestines exhibit red or livid patches, and +at other times ulcerations. + +The cattle plague is by far the most formidable malady which can affect +animals. When left to itself, or treated without discernment, it carries +off ninety cattle out of a hundred. In prior visitations, especially +that of 1750, when six millions of horned beasts were swept off in +Europe, England lost from three to four hundred thousand; and we may +suppose that the number of cattle which have perished since last June +exceeds sixty thousand. + +_The treatment_ is very difficult, owing to the contagious character of +the disease, and it has given rise to much discussion. In some +countries, the governments, considering the distemper incurable, only +seek to stamp it out wherever it may appear. They slaughter all the sick +cattle, and even those which had come near them, allowing a compensation +of half the value of the beast. This measure has not always proved +successful, the disease having in spite of it sometimes extended over +the whole of the country thus defended from its diffusion. + +England protected by the sea, and which has been spared for a century, +was taken somewhat unawares, so that some uncertainty has been witnessed +in the measures employed to arrest its course. In some districts, the +parties interested have had the good sense to form assurance funds; and +it is much to be regretted that the same plan has not been adopted for +the metropolis. + +But we cannot help what has been done; let us, therefore, be reconciled +with the past, and see what is best to be done in future for the +interests of all. What is the present state of the matter? A certain +number of districts, both in England and Scotland, are still exempt from +the typhus; in others the disease is generally extending its ravages. + +Those districts which hitherto have been spared, should institute +assurance funds, and take every precaution to secure themselves against +this scourge. In France, in Belgium, even in Great Britain, some places +managed, in 1750, to successfully protect themselves by prohibiting the +importation of any foreign cattle or animal. These preventive measures +may now be taken with some chance of success in certain parts. Ireland, +which, thanks to the published Orders in Council, seems to have escaped +up to this time from the contagion, shows us the effectual results of +these sanitary measures. + +As for the districts already infected, it is of the highest importance +to send no more tainted beasts to the different fairs and markets, +otherwise the distemper will spread indefinitely: the unsold cattle, the +sheep, the pigs, which are placed only a few yards apart, must +necessarily convey the contagion everywhere. It would even be necessary +at this time not to collect oxen and other animals together in the same +markets; we urgently invite the attention of all public authorities to +this most important question. + +At all events, the farmers and graziers who, after all the cautions they +have received, all the orders which have been published, and all the +dangers which have been clearly exposed to them, should still persist in +driving their cattle out of their abodes, would deserve censure, and +ought to be heavily fined. The best they can do, since the contagion has +not been prevented, is to submit their cattle to the treatment which we +are now going to explain to them in detail. + +It has been abundantly proved by the many convictions at the various +police courts, that the flesh of cattle seriously diseased has been sold +to the consumers, to the great injury of the public health; and if the +cholera, which is steadily and surely advancing towards us, should mix +its fatal germs with those of the ox-typhus, we must all expect +deplorable consequences, in case the flesh of tainted oxen should +continue to be sold by the butchers, as during the last three months it +has been. + +Every farmer or grazier who shall have fully ascertained that the ox +typhus has insinuated itself into his farm or his stables, must +instantly have recourse to the necessary measures and safeguards by +means of which he may limit its pernicious influence, and prevent the +spread of the contagion to his other cattle still sound and healthy. Let +him immediately divide his stock of animals into three classes or +lots--the first class must consist of healthy cattle, having had no +direct contact with the infected beasts; the second class must contain +those cattle which, though not yet sick, may become so, because they +have been in contact with those tainted; the third class will be +composed of cattle smitten with the typhus. + +The sound and healthy cattle forming the first class must be removed +from the farm, and driven to the field separately, by some other road, +in different pastures, and only after the dispersion of the morning +mists. Those which are accustomed to continue at the rack must be taken +out twice a day, for the twofold object of taking wholesome exercise, +and allowing their stalls and sheds to be cleaned. + +Their feeding must be attended to and watched with very particular care; +the rations of those which were being fattened up must be decreased, and +they ought to be sold to the butcher for consumption as soon as +possible. Let the following provisions be added to their daily +sustenance: + + Pounded oats 4 pounds. + Pounded juniper berries 1 pound. + Powdered gentian 1 ounce. + Sulphate of iron 2 drachms. + Carbonate of soda 2 " + +The herdsman who tends the cattle whilst feeding in the fields must have +them cleaned every day: he will carefully wash and scrub them; he will +not allow them to drink out of the ponds, or at any stagnant and muddy +watercourse. + +Those belonging to the second class must receive the same strengthening +and tonic ration in the morning; and, twice every day, one of the +following anti-contagious preparations: either a solution of _chlorate +of potash_ or of _permanganate of potash_; two drachms of either of +these salts dissolved in eight ounces of warm water, mixed afterwards +with a gallon of an infusion of sage or hyssop, just at the time when +the drink is given to them. + +Or you may employ, for the same purpose, a solution of arseniate of +soda--two grains dissolved in four ounces of water, and mixed with +their drink in the same way. You need hardly be told that these doses +must be reduced one half, when you have to treat a calf or a heifer, and +that the same diminution will hold good, in their cases, for all other +medicaments. _The use of these anti-contagious drinks is of the highest +importance; I recommend you earnestly to study their effects, and to +continue them even after the distemper shall have broken out._ + +These drinks having no disagreeable taste, the cattle take to them in +general; should the contrary be the case, give them in a bottle as all +men who are cattle owners know how to do. + +If the health of any of these animals among which the outbreak of the +typhus is apprehended should seem below the standard, you must apply a +purgative to those whose bowels do not operate well, and even have +recourse to bleeding in exceptional cases. + +During the absence of those cattle which are undergoing the preventive +treatment, let the hygienic conditions of their stalls and sheds be +looked to; for no circumstance must be overlooked or neglected if we +hope to withstand the propagation of so formidable a malady. Be careful +to take out the litter every day, to wash the floor and cleanse it of +the droppings, to ventilate the place thoroughly, to fumigate it with +burnt sulphur or aromatic plants, such as juniper berries, sage, +rosemary, salted with nitrate of potash and arsenic acid; in order to +promote the combustion and give effect to its disinfectious properties. +At night, camphor or tar, or naphthaline, or creosote, or even iodine, +may be left in the stable to diffuse their vapours; all these measures +are very effectual in modifying the air. + +Let us now see what must be done with respect to the sick animals +themselves. + +The typhus, as we have said, when once it is developed in an ox or cow, +usually pursues its fatal course until the last period of its cure; +generally death alone can arrest its march. Besides, the disorders which +this disease produces in the various functions of the body are not the +same at the different stages of its duration. Thus, for instance, the +fever produces great excitement in the beginning, but later it produces +exhaustion. Without being a physician, a man can understand that the +treatment to be applied to these different states ought not to be the +same. We must, moreover, observe that the typhus is of all known +distempers the most difficult to treat. It requires in the doctor a +degree of skill, of practical experience, vigilance, decision, and +sureness of hand which no man can be expected to possess at the first +outbreak of the epizootia. + +On the other hand, the constitution of the ox, so easily shaken, +undergoes in two weeks all the commotion which a man labouring under +typhoid fever would be subject to in a month. The phenomena succeed each +other with terrific swiftness, leaving scarcely time for us to act, or +for the medicines to operate. Do not, therefore, marvel at the great +mortality among your cattle, and at my repeated recommendations of the +preventive treatment by means of inoculation. + +At the outbreak, you must reduce the violence of the fever, prevent the +derangements in connexion with the nervous centres, assuage the thirst, +empty the stomachs and intestines, which will be the principal seat of +the complaint, and sometimes let blood. + +But how are you to obtain these results? By abolishing the solid +feeding, which is easily done, since the animal has lost his appetite. +Give him to drink, three or four times a day, half a pailful of a +decoction of good hay, adding thereto a sprinkling of salt; or a +decoction of wall-wort, with a drachm of nitrate of potash; or water +whitened with bran and flour, or whey, with a little vinegar. If the +animal has a tendency to cold, if he coughs, if his breathing is +oppressed, give him warm drinks, consisting of an infusion of mallow +leaves and borage, or else a light decoction of barley and oats, and +cover the animal's body warmly over. + +Now, with respect to purgatives: give the animal, night and morning, +according to the effect produced, 6 or 8 ounces of Epsom salts (sulphate +of magnesia), or an equal dose of Glauber's salt (sulphate of soda), +dissolved in two pints of honey-coloured water; or 12 ounces of linseed +oil in some warm drink; or a decoction of senna leaves and prunes, with +an ounce of sulphate of soda added thereto. + +We might point out a larger number of purgatives, but we shall desist +from so doing. Those which we have just prescribed, not being irritant +to the intestines, are the best which can be employed. + +If the animal is very restive, if he passes through alternate fits of +dejection, stupor, and great excitement, you must have recourse to +bleeding, particularly local bleeding, by opening the small veins of the +head. If the excitement does not abate you must add, night and morning, +to one of his drinks, 2 grains of extract of belladonna, or a half ounce +of powdered belladonna leaves. If the fever, at first, is irregular, and +tends to become malignant, you must then have recourse to sulphate of +quinine, 20 grains in the morning, and the same quantity during the day. + +When the disease is principally seated in the lungs, add to one of the +pectoral drinks 4 ounces of oxymel of squills, and 2 grains of opium, +giving also an emetic--5 grains of tartar-emetic to 4 pints of water--to +be taken in four times, at intervals of two hours. + +Whilst this medication is applied to the internal organs, let the animal +have unusual care taken of him; let his head be washed several times a +day with vinegar and water. + +Such is the course of treatment to be adopted during the first three or +four days. It must be, of course, followed methodically, watching and +obeying the signs of nature. The purgatives must not be given on those +days when the sick animal is bled, and the doses must vary with the +effects they produce. + +From the fourth to the seventh day the symptoms change, diarrhoea +shows itself, and the running appears at the nose, mouth, and eyes; you +must then continue the use of purgatives, but the dose must be weaker. +Those mentioned above are suitable in every way. The drinks, too, +continue the same. Sometimes, at this period of the disease, the animal +is utterly cast down, nothing can draw him from his stupor: he lies down +the whole day; in this case you give him acetate of ammonia, from 1 to 6 +ounces, in a pint of water, gradually increasing from 1 to 2 ounces a +day, according to the effect produced; and meanwhile, plain +non-acidulated drinks should be administered. + +At this stage of the disease it is right to assist the depurative work +of nature. This is effected by inserting a seton in the neck, and the +secretion of this issue is kept up by means of such an ointment as the +basilicon with powdered cantharides. Finally, the mouth, nose, and eyes +must be washed very often with an infusion of camomile and sage. + +At the last period of the distemper, the beast sinks into a state of +general exhaustion; his life seems all but extinguished through excess +of weakness. You must now sustain and keep him up by every possible +contrivance; give him bitter and stimulating drinks, beer diluted with +water, adding thereto some powder of Peruvian bark, or sulphate of +quinine. This is prepared by steeping in 8 pints of boiling water, +Peruvian bark, gentian root, centaury leaves and flowers, and hops, 1 +ounce of each; or else prepare a drink consisting of veterinary treacle, +extract of juniper, 1 ounce of each, dissolved in 2 ounces of alcohol, +and then mixed with 3 pints of water. + +When the diarrhoea becomes fetid and bloody, give, night and morning, +a clyster composed of a decoction of Peruvian bark, and a teaspoonful of +powdered charcoal from the poplar, well sifted. If the running from the +nostrils begins to stop, you must inject into the nasal orifices some +spoonfuls of a sternutatory solution, thus composed-- + + Spanish pepper 1 ounce. + Essence of turpentine 1 " + Camphor 2 drachms. + Vinegar 2 pints. + +Should any sores form on the skin, or should they arise from the opening +of purulent deposits, dress them with the following ointment-- + + Acetate of copper ½ a drachm. + Calcined alum 20 grains. + Sal ammoniac 20 " + Camphor ½ a drachm. + Common ointment ½ an ounce. + +If the natural heat diminishes greatly, if the chill reaches the hams +and skin, let the beast be rubbed all over, three times a day, with +wool, moistened with the following liniment-- + + Laurel oil ½ an ounce. + Green soap ½ " + Volatile oil of lavender ½ a drachm. + Solution of ammonia ½ " + +Simultaneously with the above, give the following cordial, to be drunk +in two draughts-- + + Cinnamon ½ an ounce. + Extract of gentian 1 ounce. + Red wine 2 pints. + +Should the animal fall into a state of lethargy, you must have recourse +to strokes of fire, according to surgical usage. + +This distemper must extend to its extreme degree of gravity before it +advances towards its cure; you need, therefore, not despair until the +last moment. At this period of exhaustion, the drinks above-mentioned +are given up, or you add nutritive beverages to them, such as beef-tea, +fat soups, milk, and farinaceous drinks. + +If the animal holds on, and his appetite returns, which will be shown by +the desquamation of the nostrils, by the return of rumination, by the +habit of the beast to look right and left, to question you in a manner, +add cut straw to his nutritive drinks: send him out every day into the +open air, and let him return by slow degrees to his habitual feeding. +But it is extremely important to watch the intestinal functions; to +diminish and change the food, if the diarrhoea returns; as such +relapses often cause the death of an animal considered out of danger. + +Such, then, farmers and graziers, is the treatment to be opposed to the +ox typhus: it is simple as respects the remedies, and I have deemed that +it ought to be so, in order that the medicines prescribed might be had +everywhere, and at a cost which the poor man could command as well as +the rich. The disease is variable, it is not always equally deadly; and +there comes a moment when in some sort it cures itself, with a little +assistance and watching. The great point is, to be careful and vigilant, +to attend to nature and the instincts of the suffering cattle, and lend +yourselves to both. + +I cannot reproduce here the instructions given by the Privy Council to +protect your cattle from contagion, and above all not to propagate it, +but I shall refer you to Doctor Thudichum's _Memorandum_, page 257. This +exposition is too complete to need anything added to it by me; study it +well; let it be your monitor and guide; read it over again and again; +your own interests and those of the whole country depend on the manner +in which you shall treat this admirable warning. + +There are in this disease, as in every other, unforeseen varieties and +complications, such as those which are brought on by the gestation and +abortion of cows, and those proceeding from prior disease; for these +accidents you will provide. Moreover, such a terrible distemper can only +be treated according to the advice of a professional man. Call him in, +then, follow his advice and prescriptions with rigid exactness, and do +not attempt to do better than he; and, above all, arm yourselves against +the insidious pretensions of quacks and charlatans, whatever mantle they +may put on to hide their ignorance. + + + + +FOURTH PART. + + _Suggestions on the Improvements to be effected in the Study + of Medical Science, in order that we may be in a Condition + to confront Diseases generally, but Epizootic and Epidemic + Diseases in particular._ + + +The epizootia of bovine typhus which is now extending its unrestricted +ravages over this island, and which has assumed the magnitude of a +general calamity, has naturally excited and stirred up the public mind. +Thoughtful and earnest men could not look on and witness unmoved the +ever progressive march of the scourge; but each observer has, +consistently with his means and qualifications, striven to find a remedy +to resist the evil. Thus, we have seen, and with respectful interest we +have watched, the gentlemen of the press, and other men of letters, +economists, scientific men, and, above all, physicians, producing from +day to day in the newspapers articles and letters of remarkable merit +on the all-engrossing subject of this epizootia. The re-opening of the +medical colleges furnished the skilful professors at their head with a +seasonable opportunity to consider this dire distemper, according to the +views of general pathology and medical philosophy, and this they have +done with unquestionable talent and ability. Still, something remains to +be said on this important matter, and since I have taken up my pen, like +others, I wish to mingle my voice with that of my brethren, and inquire +whether the time is not come to avail ourselves more fully than we have +done yet of the grand discoveries of the exact sciences, which, with +respect to the science of medicine, are the instruments of its progress. +And my object in doing so, is, that we may, as far as possible, rise to +a level with the ordeal which the future may have in store for us. + +Medicine is at once an art and a science. An art it has been at all +times, and in every age of civilized man; but it became a science only +when human knowledge had acquired a certain expansion; when natural +phenomena had been tested and explained; when mathematics, physics, +chemistry, botany, general anatomy, general pathology, had enabled the +inquiring physician to study with important results whatever belongs to +his theme; to understand the serial chain and connexion of bodies with +each other, in the mineral, vegetable, and animal kingdoms, and to +investigate their immutable laws. Uric acid, as we see with the +microscope, will always crystallize in rhombohedrons, according to a +fixed law; the vegetable cell, the germination of a seed, must obey, and +always submit to, the innate and indestructible forces inherent in them. +That which is true in the vegetable is true in the animal world, as +regards the pre-established order which regulates and controls the +phenomena of life. These laws which govern the development of organic +phenomena being immutable and everlasting, permit the different +generations which succeed each other on our globe to build upon a +durable basis, which certifies to the slow and laborious, but +irresistible march of human progress. + +Medical science being in truth only the application of other positive +sciences to the preservation of health and the cure of diseases, +continues like them to perfect itself incessantly; but all it can do is +to follow them at a distance, and it can never hope to reach their +degree of superiority. + +These are truths which have been long admitted and felt by us. +Therefore, we have appealed for assistance to the discoveries of the +natural sciences: physics, chemistry, have in our hands become effectual +means of observation and analysis; and we, in our age, gain more +knowledge in fifty years than our forefathers did in several centuries, +for they were then necessarily rather artists than scholars. In a word, +medical science or biology is constituting itself, and if it be fully +conscious of its impotence in the case of many diseases, it also knows +its progressive improvement. It is striving to achieve the highest place +among social institutions, and the day may come when it shall obtain it, +for nations will then owe to us their health and life--that is to say, +their earthly happiness. + +The laws by which organic phenomena are regulated, are, we have said, +everlasting; we may also declare that they are general. One of these +laws common to the plant, to the shell, to every species of vertebrata, +reappears in man, whose organization comprises all the functions divided +among the other organic kingdoms. Not only does the organization of man +obey the laws which govern the vital phenomena of other animals; not +only does he possess their organs and functions, but he is a tributary +subject to their diseases. So that the knowledge of the laws affecting +the functions and diseases of those creatures which are placed below him +in the scale of animals ought to be the first foundation of all medical +study. + +These truths are too manifest to be new; they are written and professed +everywhere, and every one amongst us has received general notions of +comparative anatomy and physiology at the beginning of his course of +study. But let us admit that these notions only served to expand the +circle of our knowledge and ideas, and that we seldom or never apply +them to the practice of our art. It would have been very different had +we received at the beginning of our medical novitiate, not merely in +theory and books, but practically and experimentally, precise notions of +anatomy, physiology, and, let me add, of the _pathology of all +animals_. Let us suppose for a moment that the task had been imposed +upon us before entering upon the study of human maladies, to observe the +structure of plants and animals, to submit their tissues to +microscopical examination and chemical analysis; to study experimentally +all their functions and diseases, and acknowledge that had such been the +case, the anatomy, physiology; and pathology of man would have been far +better understood, and that most of the difficulties against which we +now contend in vain in our helplessness, might easily have been +overcome. + +Comparative anatomy and physiology are the first conditions of all +medical instruction of a serious character; there can be no doubt on the +subject, but the evidence being not perhaps so palpable with respect to +comparative pathology, it will not be useless, therefore, to enter into +fuller particulars as to this subject. + +We know not whether any one has ever sought to retrace the first origin +of our diseases in the animal kingdom, but it would undoubtedly be a +study of great scientific interest. As for us, we gladly believe that +man, created to be the sovereign lord of the earth, did not originally +receive the principle of every organic disease with which we see him +affected. It seems to us probable that he was created sound in body and +in mind, but unequal is his vital powers, and in his faculties and +talents, the social functions being various and dissimilar, and subject +to physical and moral infirmities. We think it likely that plants and +animals, from which, in course of time, man's substance is formed, have +transmitted the first causes, the germs of some organic diseases with +which they were themselves affected. We see in this transmission of +animal diseases to man, a connecting link, which appears to us to be a +condition of harmony, order, peace, and happiness among all living +beings. It seems to us that the first injunction of a legislator should +be--_love other animals like yourselves_; for if man had practised this +maxim, he would have logically applied the same to his fellow-creatures; +and no doubt, with such principles to guide them, past generations would +not have bequeathed to us the innumerable calamities we have had to +deplore. + +We think that we receive from animals some of their diseases, because +the fact is palpably evident; thus they have parasitical diseases, such +as favus, tænia, psora, trichinosis, which they transmit to us. They are +likewise smitten with small-pox, typhoid fever, and with typhus; and +under certain given conditions they may transmit them to us. They die of +consumption and cancer, and it is probable that they transfuse into us +through their milk and flesh the germs of these diseases. Finally, we +have our epidemics as they have their epizootics; and here we will limit +our instances of this reciprocation. + +It is certain that the study of these maladies in animals would have +been for us the source of precise knowledge, which, if well understood +and explained, would have often led to their preventive treatment. This +is what has occurred in the case of small-pox; it is what will one day +occur in typhoid fever, in times of epidemic, as will be the case in a +certain number of other general or local diseases. + +In truth, some complaints now looked upon as inherent to the human +species, were originally foreign to it; most parasitical diseases +belong to this class. Thus man has not the _psora_, or itch--the +disease does not properly belong to him; the parasite which engenders it +is not bred in him, it is always transmitted to him by animals. It is +the same with the tænia, or tape-worm, with the trichina, or fine +hair-worm. + +Medical science, instituted on the bases of comparative pathology, would +have made the study of diseases in the brute creation, not the +collateral, but the principal object of its inquiries. It would have +applied itself to the cure of the lower animals; and whilst learning to +cure them, it would have ensured the cure of men's diseases. + +If such be the case, can any one believe that the treatment of diathetic +and hereditary maladies would be, as they still are, insoluble problems; +and that the physician would have the misery of seeing decimated, whilst +he helplessly looks on, a large part of the population, condemned +inevitably to die of consumption and cancer? Would every man smitten +with hydrophobia be irrevocably condemned to death? Assuredly, it would +not be so. + +That the physician should have been reduced to the painful necessity of +confessing his want of means, when medicine could be nothing more than +an art, we admit; but now that science has grown up and come of age, +society has a right to challenge him to do, what in past ages could not +have been expected of him. Briefly, we think that the time is come, by +blending comparative pathology with anatomy and physiology, to construct +one of the bases of the tripod on which medical science will have to +rest. The success which has already been achieved in this direction is a +certain guarantee for those which we may hope for hereafter. + +Such is our deep conviction, and perhaps we have some title to speak out +decidedly on this point, as we have long since exemplified our precepts +by actual proofs. + +Persuaded for many years that comparative pathology afforded to +industrious men a new mine, rich in precious veins for working, we +several times endeavoured to explore this fertile field. But, +unfortunately, our means of action not being consistent with our +sanguine expectations, we were repeatedly compelled to suspend our +pursuits, until at last we found at the Ecole Vétérinaire d'Alfort, the +favourable opportunity and the essential conditions of which we had so +long been in quest. + +Grieved at our helplessness to stay the ravages of pulmonary +consumption, I formed one day the resolution to study that wasteful +complaint in animals in order to discover, or at least to look for, the +required remedy. With that view, I confined in a dark, cold, and damp +cellar a number of animals to practise on: birds of different species, +rabbits, a monkey, a dog, &c. To these animals I dealt out a deficient +quantity of food. The monkey, as might have been expected, was the first +to be affected, since in our climates they all die of consumption. Next, +and for the same reason, it was the parrot's turn; then the chickens and +ducks died; after them the rabbits;--in fine, at the end of fourteen +months, the dog alone survived. All the rest had sunk under consumption, +and exhibited tubercles in different organs--in the lungs or mesentery. + +It was then necessary to have the counter-proof: to place a second set +of animals in the same conditions, to produce the disease again, and +attempt its cure. But the first experiment had been a long one, and I +was forced to relinquish the inquiry, which, moreover, was above my +means at that period. + +On another occasion, it seemed to me strange that we should be obliged +to open the bladder of patients suffering from the stone, or to subject +them to lithotrity, which has also its perils. Nature, I said to myself, +forms calculi by uniting organic elements, by crystallizing them, and by +cementing them with vesical mucus. But would it not be possible to cure +the disease by employing contrary means--dissolving the calculi in the +bladder by means of continued injections, changing the chemical agents +according to the composition of the calculus, and adding thereto the +action of a galvanic current? + +After this, I pursued my inquiry in this direction. I studied for +several months the chemical composition of calculi by examining them in +their dissolved state; and I saw that those in which the alkaline bases +prevailed, being submitted to a diluted solution of tartaric acid, which +would not injure the bladder, crumbled after a time; that the calculi +with excess of acid were also attacked by an alkaline solution; in +fine, that the calculi of oxalate of lime alone seemed to resist the +action of these chemical solutions. But it is well known that they +sometimes defy all lithotrite instruments, and compel us to have +recourse to the knife. + +These preliminary experiments over, it was necessary to come to their +application, and for that purpose to make experiments on some animals. +The canine species, omnivorous like ourselves, was chosen in preference. +Bitches were selected to be practised on; for as their urinary passages +are wider and more flexible, it enabled me to insert in the bladder +fragments of calculi already analysed, which were to serve as the nuclei +to the stones they were intended to develop. + +This second assortment of animals, penned up apart from each other, were +supplied with different modes of sustenance: some of them were put upon +a diet of meat only, others on a farinaceous diet, and a third set on a +mixed course of food. These experiments were being regularly followed +up, when an important and unforeseen event compelled me to desist at the +end of six months. The poor animals were destroyed; but all of them, as +I had anticipated, had generated calculi of various chemical +composition. + +These unfinished inquiries concerning comparative pathology, thus +interrupted in spite of myself, might, had circumstances allowed them to +reach the goal, have authorized us to undertake in man the dissolution +of stone in the bladder. And how would this have been effected? By +seizing the stone between the two ends of the catheter with the double +current, and by injecting a well-sustained series of dissolvents into +the patient, whilst lying at his ease in a recumbent posture. + +Nor is this all. They would likewise, I believe, have thrown some light +on the organic production of calculi, on the lithic diathesis, and the +particular formation of the stone; and led us, in some degree, to their +preventive treatment, which is always superior to the curative remedy. + +On a subsequent occasion, I betook myself to my task under more +favourable conditions. I undertook at Alfort, conjointly with Professor +Delafond, a course of experiments on the cutaneous diseases of animals +in relation to comparative pathology, having already, whilst walking +the hospitals, published a work on the "Entomology and Pathology of +Psora in Man," which had been printed at the expense of the Academy. + +These inquiries and examinations at Alfort were persisted in for five +years, and were considered to have led to very satisfactory results as +regards general pathology. But I have spoken of these labours in the +first part of my book. + +Pardon me, reader, and do not suppose that vanity or any desire to +parade myself has induced me to refer to these experiments. No; my only +object is to show to what results similar studies might lead, if they +were executed on a large scale and on the whole animal kingdom; if, +instead of these partial efforts made under favour, some special and +appropriate medical institution encouraged earnest experimentalists, +supplying them without stint with all necessary resources, and with the +best and completest instruments of observation. + +Will any one deny, that if medical science had been settled on this +foundation fifty years ago--that is to say, since the exact sciences +first began to provide us with the means of investigation, it would now +be so impotent? Epizootias and epidemics would not thus flout us as they +do; the cholera would no longer be an enigma, nor the ox typhus so +incurable. No! a hundred times no! Medical science would not he helpless +and impotent in our day, had our forerunners been more mindful and +provident. + +But, instead of this, the science for which we plead would have done +good work. It would have made and confirmed an infinite variety of +observations on the brute creation; it would have transmitted our +diseases to them as they transmit their diseases to us; it would have +treated and cured these diseases, and every such cure would have been a +new triumph, a new victory for mankind. + +For instance, during an outbreak of cholera, this science would have +been ready and prepared to try different experiments on men and animals; +it would first have communicated the cholera to animals, and then +submitted them to a variety of experimental treatments. This cholera, +which is not an infectious fever, with its regular and assigned periods, +like typhus, and which we are not obliged to suffer to run its course, +but which, on the contrary, is a nervous affection produced by some +poisonous miasma, the toxical effects of which first of all assail the +nervous system and then more particularly the great sympathetic; the +cramps being but the result of a reflective action--_this cholera, we +say, must be curable_, and well-advised experiments would reveal the +remedy we want for it, nor should we have to wait long for the +revelation. + +As for me, I once made a desperate attempt in this direction. It was +during the cholera of 1854. We remarked whilst dissecting subjects, as +is always the case, that the mucous membranes of the stomach and +intestines, which were in a manner paralyzed, had suffered the fluid +parts of the blood to ooze out on the surface. Hence the cause of those +vomitings, and those watery and colourless diarrhoeas which nothing +can stop, so that at a given moment the patients die, poisoned, of +course, but dying more particularly through want of circulation, the +blood being reduced to its solid parts and unable to circulate any +longer. Relying on this fact, and trusting for want of better to the +secondary effects, I strove to restore to the blood its aqueous part, +and, if possible, to re-establish the circulation. + +With this view, I went to the Hôpital de la Charité, provided with all +the requisite instruments. Choleraic patients were being brought there +every hour. The experiments being new, venturesome, and _dangerous_, in +the eyes of the hospital directors, I was only suffered to operate on +the moribund. The first patient, considered to be in a state +sufficiently desperate to be given up to me, was a woman, forty-five +years old. She was literally insensible, and thoroughly cold. I +hesitated for a moment to try the operation under conditions so +unreasonable, so preposterous--almost upon a corpse. The radial arteries +in the arm had ceased to beat, and the heart alone kept up a feeble +circulation at the central parts. At length I opened the vein, from +which not a single drop of blood proceeded, and taking the usual +measures to prevent the air from having access, I gradually and slowly +injected two ounces of alkaline solution, the process of injection +lasting twelve minutes. It was scarcely over before the patient +half-opened her eyelids, and looked about her with astonishment; the +pulse became perceptible for a few moments, and all present thought she +was saved. We put a few questions to her; the patient could not answer +us, but she nodded as much as to say "yes," when asked if she felt +better. But this was all we could do in her case. The circulation +stopped again, the patient relapsed into her state of insensibility and +died two hours after the injection. + +The result obtained in this instance had not answered our expectation. +However, the circulation had for a minute or two resumed its course, and +a flash of reason had once more shown itself. + +I thought the experiment ought to be repeated, and accordingly the next +morning I made another trial. The patient this time was a working +shoemaker, thirty-eight years of age, exactly in the same far-gone, +hopeless state as the patient of the day before. In his case, the inward +commotion caused by the injection was more powerful; twenty minutes +after the injection he was able to see, to understand, to speak, to +raise his head; but this vital recovery was, as in the former case, but +of short continuance, and two hours and a half after the operation the +man expired. + +After these experiments I dissected the two bodies, and then, finding +that their lungs were infiltrated with water, I understood that the +alkaline solution had not been assimilated, that it had stopped in its +passage into the pulmonary parenchyma, to the detriment of the functions +of the hæmatosis. I also understood that the proper injection, instead +of distilled alkaline water, would have been the serum of the blood, +drawn at the very moment from some man or animal. + +The conclusion which I drew from these experiments was that a variety of +operations, made at different stages of the malady, might lead to +beneficial results, especially if we succeeded in transmitting the +cholera to animals, as that would enable us to test a large number of +curative agents and to pursue a methodical course of experimentalization. + +From all I have said, I infer that life, health, and disease, being +subject to the same laws throughout the whole animal kind, it is certain +that the physician should possess precise knowledge as to the +organization, the functions, and diseases of animals. That by proceeding +in this manner, we shall advance from the simple to the complex, from +the plant to the animal, and from the animal to man. That we must of +necessity emerge from the state in which we are now entangled BY FOUNDING +AND ESTABLISHING IN LONDON A COLLEGE OF THE NATURAL AND MEDICAL SCIENCES. +Every medical pupil might spend two years in this college, receiving in +it an experimental and practical training; he would devote himself in it +to the chemical analysis of all bodies, to physiological experiments and +tests, without limit and of every kind. + +Most deeply do I appreciate the many difficulties and obstacles that +would interfere with the execution of such a design. In our civilized +age, nations seem rather bent on seeking out the means of exterminating +each other than of protecting themselves and animals from epidemics and +epizootias. It is believed that every first-rate kingdom now spends from +400 to 500 millions of francs (16 to 20,000,000_l._) annually in +maintaining their land and sea forces, whilst one-half of their +populations are living in misery and ignorance, in disease and +corruption. The time is not come--shall we ever see it?--to employ the +vital powers of the peoples, to better incessantly their social +condition. Perhaps, by reason of its organization, the Government of +this country would not be authorized to devote 100,000_l._ or +200,000_l._ to the establishment of an institution like the medical +college I suggest, notwithstanding its paramount necessity. But England +is in the habit of doing great things independently of the Government. +In default of the ruling powers, then, let me appeal to the national +initiative, for if the spectacle which we are at present witnessing was +not, in the case of England, one of those trials which invigorate a +people by the salutary teachings which they bring; if it did not induce +them to take some energetic resolution by which their interests would be +saved and their power enlarged, it would indeed be a deplorable sign of +the times and make us despair of its future. + +Moreover, to show the urgency of founding a _College of Natural and +Medical Science_, let us add, that in every other country they are +endeavouring to unite this indispensable complement to medical +education. The German universities, the Faculty of Paris, have, for +several years past, incorporated a course of comparative pathology, with +the other series of public lectures. + +It is not a mere Utopia that we propose, but an extension and +improvement, all the parts of which are already prepared. If this +College could be thrown open to-morrow, competent professors would be +ready at the call of duty to indite the programme for this instruction +within twenty-four hours; and as for the professors themselves, there +would be enough to choose among the large body of efficient scholars who +do honour to the country. + +If we have been rightly understood, we desire to see established in +London an institution which would afford an equivalent to what exists in +Paris, at the Museum and Collège de France, where numerous courses of +lectures on anatomy, physiology, physics, and chemistry are given. Only +in London this special college would be formed and organized on such a +scale as to bear away the palm from every previous foundation of the +same kind; it would be an institution unexampled in the world, out of +whose halls would one day come anatomists, physiologists, and +pathologists of the very highest order of excellence.--But organic +matter would not be the sole object of this instruction, for the animal +is something more than matter. Courses of medical history and +philosophy, of really general pathology, would introduce the students to +the grand phenomena of nature, to the great laws which govern the worlds +and the globe; and descending from the heights of science to the +observation of the infinitely minute, they would never forget the +important part of the vital powers, and of that unknown power called at +different times by the names of πνευμα, _archéc_--_mind_ and _soul_. + +The Regent's Park would, we think, be the proper site for this college, +as the contiguity of the Zoological Gardens would afford continual +opportunities for investigating the diseases of animals. + +Moreover, this college would not trench upon or interfere in any manner +with those medical and veterinary establishments which at present exist; +it would ally itself with, and complete them, nothing more. The +instruction received at this "College of Natural and Medical Science" +would be so useful and necessary, and so attractive withal, that the +sons of the great families would come to it to finish their collegiate +studies, to the great benefit of the country. Other young men, in +considerable numbers, would flock to it from various parts of the world. +The foundation of such an institution would be an epoch in the history +of science, and would give England another claim to the esteem of +nations. + +I conclude, then, with a conviction that a nation which owes to Lord +Bacon, the founder of experimental philosophy, his imperishable book on +the _restoration, the method and teaching of the sciences_; to Harvey, +the circulation; to Priestley, the constitution of chemistry; to +Sydenham, the modern Hippocrates, his treatise on "Practical Medicine"; +to Jenner, vaccination; and to Charles Bell, the discovery of the +sensitive and motor nerves--is a people too great and too enlightened to +retrograde; and that, if the epizootic of ox typhus did find them at +first unready and disarmed, they will in the end convert this disaster +into a new source of greatness and strength. + +Such is the sincere hope which I cherish and the prayer I offer up for +the happiness of a country which, for the future, has become my own. + + + + +APPENDIX. + + +NOTE A. + + BREMEN, August 30. + +The following report, drawn up by two German veterinary surgeons, of a +recent visit to London to examine into the cattle murrain, has been +furnished by the agent of the North German Lloyd's at Nordenhamm:-- + +"On Wednesday, the 9th instant, we, the undersigned, were requested to +be at Nordenhamm, if possible, the following morning. Upon our arrival +we were asked by the agent of the North German Lloyd's, who had +consulted with several of the chief cattle exporters, to undertake a +voyage to London at once in the steamer _Schwan_, in the interest of the +cattle export from the Weser. The object of our mission was, first, to +examine as closely as possible into the epidemic cattle disease raging +in and around London for some time past; then carefully to observe the +treatment of cattle upon the vessel during the voyage, upon arrival, and +at the time of disembarkation; lastly, to use every means in our power +to prevent obstacles being opposed to the continued export of cattle +from these ports to England. + +"Furnished by the agent of the North German Lloyd's with letters of +introduction to cattle dealers in London, and with the necessary funds, +we left Nordenhamm in the steamer _Schwan_, Captain Christensen, at 4 +P.M., on the 10th instant. The vessel carried 347 head of large +cattle, 2 calves, and 260 sheep. Favoured by very fine weather, we +arrived in the Thames at 2 P.M., on the 12th. At the beginning +of the voyage the animals were rather uneasy, trampled a good deal, and +caused considerable motion in the ship; after a time, however, they +became quiet. A sharp, penetrating smell was easily perceptible in the +'tween decks of the ship, which was quickly removed upon a light breeze +springing up, by means of the excellent ventilation and numerous +air-pipes and wind shafts. The animals were several times watered, and +it was easy to see how greatly they were refreshed. The hay in the +racks, on the other hand, was hardly touched. + +"Upon arriving in the port we were introduced by the captain to the two +veterinary surgeons stationed here to inspect the cattle, and witnessed +the rapid disembarkation of the cargo, all of which were thoroughly +healthy, not one being condemned. The cattle, when landed, were +immediately brought to carts standing in readiness and transported to +London, where they are cleansed and then driven into the adjacent +fields. + +"After doing all in our power to attain the object of our journey, we +went back to the port to wait for the _Schwan_, having first thoroughly +cleansed the clothes we had worn during our inspection of the diseased +cattle. The _Schwan_ came in shortly after our arrival, and disembarked +256 head of large cattle, 12 calves and 400 sheep, all in good +condition. Mr. Philipps, the London agent of the North German Lloyd's, +was on the spot, together with several reporters from newspapers, who +wished to see by personal investigation how and in what condition cattle +are brought from the Weser. + +"We re-embarked on the _Schwan_ upon the 19th. The crew were engaged +during the voyage in carefully cleansing the ship. The weather was fine, +and we arrived safely at Nordenhamm upon the 21st. + + (Signed) + + "G. J. RIPPEN, + "Veterinary Surgeon at Seefield. + + "H. FASTING, + "Veterinary Surgeon at Schwey." + + +NOTE B. + +Professor Simonds having had such opportunities of investigating those +diseases as they existed in England and in foreign countries as were +possessed only by a few Englishmen, might be permitted to offer a few +observations. He had been appointed by the Royal Agricultural Societies +of England and Ireland to proceed to the Continent in 1857, when there +was a rumour that the disease which existed among cattle in this country +at the present time was prevailing in Mecklenburg. Consuls sent +despatches that the rinderpest was prevailing largely, and the +Government, as a precautionary measure, closed the ports against the +introduction of cattle from the Baltic to this country. He found, +however, from his observations abroad that since 1817 there had been no +disease of this kind westward of a line between Revel in the Baltic and +the Gulf of Venice, but to the eastward of that line it had existed. He +came up with the affection at the Carpathian mountains, where it was +raging in 1857 just as it is raging in England at the present time. Not +only had it existed there, but it had been carried into the interior of +Russia in the ordinary method of the cattle trade. A person who was in +the habit of purchasing cattle attended a fair and bought a number of +animals, and took them to his own farm, and in the course of ten days +one or two were seized with the disease, and the result was there was a +gradual spread of the evil in that district. It gained ground until the +Government instituted the sanitary police regulations, which, though +they were such as would be considered strange in England, were, he +believed, absolutely necessary for the extirpation of the plague. It was +undoubtedly true that no foreign animals had been seized at our ports or +in the metropolitan market; but it was not necessary for the case they +had in hand to say whether the disease was or was not of foreign +importation. There was this fact before them, that it was not until the +month of June that the disease appeared in England. A certain number of +animals came out of a diseased district. He had documentary evidence +that animals came from Revel and came from the district of Esthonia. He +had before him proof that the disease now in England was raging in that +district. They had proof that shortly after the arrival of those cattle +in England the disease manifested itself here. He admitted there were +difficulties in the way of checking the importation of foreign cattle. +The Government had its eyes open to the matter, and he did not think it +possible for the Government to have done more than they had done or to +have done more quickly what they had been doing. At this moment half the +supply of the metropolitan market came from foreign countries, and he +did not wish to convey any reflection by saying that this disease had +its origin from abroad. He would admit that the animals from Germany and +Hungary were coming in a healthy condition; but he could not admit that +they came from Russia, Poland, or Galicia in so perfect a condition, +because the regulations there were not sufficient to stamp out the +disease. The Government had made an inquiry as to the general health of +cattle on the Continent. They believed France, Belgium, Holland, +Schleswig-Holstein, Oldenburg, and a large part of the Continent that +supplied cattle to this country were free from disease. This went to +show that we had admitted a disease not from where we received our +supplies of meat, but from some other district. Then it must be +associated with the fact that it came into this country when animals +arrived here from an infected district in Russia. Animals from Germany +and Hungary were often shipped and mixed with others from a diseased +district. As regarded the disease being spontaneous, we had been free +from it for twenty years. What was the state of our cowsheds fifty years +ago? Were they not in a more filthy condition than they are now? If, +therefore, the disease had been induced from common causes it would have +been here years and years ago. It was no reflection to say that a great +many cases could be traced directly to the metropolitan market. Take one +case which occurred in Sussex. Certain cattle had been bought in the +metropolitan market and were taken home. In three or four days they were +ill, and presented symptoms of this affection. In a few days more the +cows and calves were dead. In another instance calves were bought in +Chichester Market, where they had been taken from London. The result was +the death of twelve cows and ten calves. The people had other cattle on +the same farm, and not one of them took it. He could say, too, that +persons who had only one animal had lost it by the disease. How had the +disease got into Norfolk and Kent but by the animals which went from the +metropolitan market? He could prove by documentary evidence that it was +so. He could show there was not a single instance where the origin of +the disease could not be traced to the metropolis. It was the most +fearful visitation that had ever been seen in England. They had adopted +a system of compensation in Norfolk, and if by this meeting something +was done to shut out the animals of infected districts, no doubt the +promoters would receive not only the thanks of London, but the country +generally. + +Mr. Gibbins--Now, if the disease came from abroad, and diseased cattle +were shipped on the other side of the sea, no doubt the voyage would +concentrate and aggravate the disease. The Government inspectors +reported, however, that not one instance had been seen of foreign cattle +so diseased, nor had any been seized and destroyed in London or anywhere +else. Whether the disease came from abroad or elsewhere he was not able +to state. Sir George Grey asked him whether he had found any disease +among the foreign cattle that came into the market. He said not one. +They had, no doubt, many instances of the disease amongst the cows that +were ordinarily called milch cows, but that were not milch cows when +they came to market, because one effect of the disease was to deprive +the animal of milk. These were then sent to the market and sold as fat +stock. He could only say they had had no cases, except in cows, whether +they came from the dairies in London or elsewhere. + + +NOTE C. + +M. Dembinski, Professor of Analytical Chemistry and Natural Science, had +also addressed a communication to the Lord Mayor on the subject. The +prevalent Rinderpest, he said, originated in the steppes of Podolia, +from which considerable herds of cattle were exported through the +steppes to Moscow, St. Petersburg, Riga, and Revel, and thence to the +ports of Memel, Königsberg, Dantzic, Hamburg, Kiel, and the Hague. +_Deprived of congenial food and pure water on their transport through +the steppes, and then arriving at marshy lands, the exhausted animals +drank the stagnant water, which, during hot weather, exhaled a +pestiferous malaria, and infected them with a predisposition to the +epidemic in question, which developed itself into a kind of fever on the +voyage to England in a crowded condition._ + + +NOTE D. + + INTERNATIONAL VETERINARY CONGRESS, VIENNA, + August, 1865. + +With regard to the cattle plague, it may be well to state that Austria +has been most unfortunately situated, from the readiness with which +Russian cattle have been admitted into the country at various parts of +the western and southern frontiers. At the opening of the Congress this +difficulty was particularly noted by the Ministerial counsellor, Dr. +Vell, who attended on behalf of the Government, for the purpose of +welcoming the assembly, and giving an assurance that its deliberations +would meet with all the attention they deserved. He specially referred +to the fact that the laws relating to cattle disease prevention had been +entirely revised in 1850, but that the Steppe murrain continued to be +introduced by smuggled stock into the western and southern provinces of +the State. It was therefore necessary to attempt a more effectual +control over the propagation of so disastrous a malady. + +Herr Pabst welcomed the meeting on behalf of the Minister of Trade. He +said that the value of the cattle of the Austrian dominions considerably +exceeded one hundred million pounds sterling (one thousand million +Austrian florins), and that cattle plagues completely put a stop to the +development of that essential branch of agriculture which embraces the +improvement and increase of live stock in a country. He assured the +assembly that all would be done that was possible to improve the +existing state of matters, and that he hoped they would greatly aid the +Government by the discussions which would take place and the conclusions +at which they would arrive. + +I may state, by the way, that an opinion rather generally expressed by +some, and stoutly maintained by others, was that the peculiar +disposition of some of the Austrian subjects, and the feeling existing +in Hungary against State measures, rendered the law, to a great extent, +inoperative. I can, from personal experience, state that although +stringent and most efficient means are used for the suppression of +cattle plagues, and with the best results in Austria proper, there is +great difficulty in carrying out the law in districts where Austrian +rule is at a discount. Indeed this is clearly indicated by the manner in +which the Rinderpest penetrates into Austria, where the laws are similar +to those in the kingdom of Prussia, which is, and has long been, +completely protected from invasions of the disorder. + +At the meeting of the first International Congress, held in Hamburg in +1865, Dr. Röll stated that owing to the length of time to which the +quarantine for Russian cattle extended on the Austrian frontier, herds +of cattle were often smuggled through, and companies had been formed for +the purpose of insurance against seizure by the authorities. The +unlawful traffic was therefore carried on with comparative safety to the +dealers, who cared not what misfortune they brought on a country if only +their personal ends could be served. This question was the first to +occupy the attention of the Congress last week; when a resolution was +proposed to shorten the period of quarantine for cattle from Russia +into any country from twenty-one days to ten. The discussion was keen. +It was stipulated, however, that the quarantine should be carried out +most strictly over all parts of the frontier, without respect to any +breed of cattle or other circumstances which might be brought forward as +exceptional reasons for retaining animals in quarantine. The committee +appointed to prepare a succinct report on the subject included +Professors Unterberger, Seifmann, Werner, Zlamal, Hertwig, Haubner, and +Röll; and the committee decided in favour of the shortened quarantine, +on the following conditions:--First--When the establishment of +quarantine institutions is effected in accordance with the requirements +of trade and the peculiarities of the frontier, special attention must +be paid to the erection of quarantine stables, &c., where there are +facilities for procuring an abundance of fodder and water. Second--The +animals to be kept under efficient veterinary supervision wherever they +have to submit to quarantine. The inspectors must be properly qualified +veterinary surgeons. Third--The use of a brand to indicate that the +animals have been in quarantine. Fourth--The effectual disinfection, by +washing and otherwise, of animals as they leave the quarantine. +Fifth--The introduction of a poll-tax along the eastern frontiers, and +the appointment of proper veterinarians to be on the watch as to the +health of cattle along the frontiers. Sixth--Careful supervision to be +placed over the traffic in cattle wherever it takes place in a country. +Seventh--The punishment to the full extent that the law allows of all +who break the rules relating to quarantine or other means for the +prevention of the cattle plague. + +Professor Hertwig, of Berlin, whose opinion is always listened to with +great respect in veterinary circles, stated his reasons for adopting +these resolutions now, whereas in 1863 he was against shortening the +period of quarantine. He referred chiefly to the importance of not +offering temptations for cattle dealers to evade the law by insisting on +unreasonable restrictions. The feeling of the assembly was greatly in +favour of avoiding vexatious and expensive measures, which might greatly +interfere with the employment of capital in cattle traffic. A small +number of professors, not exceeding eight or nine, held out for a +quarantine of twenty-one days. + +It may be as well to state that quarantine regulations, which have been +regarded as almost useless in the prevention of human disorders, from +the great difficulties in the way of carrying them out efficiently, are +recognised as of great value in controlling the propagation of cattle +plagues. It is possible to control the movement of herds, and the +governments of Central Europe have found it absolutely essential so to +do. Indeed, the ablest medical men who have written against the adoption +of a quarantine system for human small-pox and cholera, such as +Professor Siegmund, of Berlin, acknowledge its value and absolute +requirement with regard to the Rinderpest. A professor from Galicia +argued in favour of controlling the movements of people wherever the +disease appeared, and no fact seems to have been better ascertained than +that of the communication of the Rinderpest from herd to herd by human +beings. Professor Jessen, of Dorpat, states that in Russia the malady +was at one time speedily propagated by the people, who regarded the +destruction of their stock as a visitation of Providence, and who +summoned a priest into their stables to pray with them that the plague +might be stayed. Moving from farm to farm, the malady was by this means +rapidly transmitted. In Hungary, many outbreaks result from people +dressing the carcases and hawking about the meat, which, even where +human beings remain uninjured, is deadly to the cattle whenever the +water with which it is washed is thrown about the yards, or the meat is +hung up near sheds containing living animals. + +The members present at the International Congress spoke in favour of +establishing a fund, apart from the Government grants, for the payment +of diseased or infected animals which have to be slaughtered with a view +to the prevention of the plague. Special precautions were suggested as +to the transmission of articles the product of diseased animals. + +1. Perfectly dried skins, the points of horns cut off, as they often are +for commercial purposes, the salted and dried intestines of cattle, +melted tallow, wools, cowhair, &.c., could be freely allowed to pass +unobserved. + +2. Entire horns, hoofs, &c., which are detached from the soft parts, but +which often contain adhering flesh, &c., should be disinfected with +chloride of lime. + +3. As melted tallow is often conveyed in bags which may be charged with +the poison, those bags should be washed with chloride of lime solution. + +4. Fresh bones, fresh skins, and intestines, unmelted tallow, raw flesh, +and fresh sheepskins, should not be sold whenever the Rinderpest exists +in a district. + +According to all the accounts which reach us, the foreign observations +and resolutions may be of essential service in England. The members of +the Assembly were informed by Mr. Erner of the origin and the progress +of the cattle plague in England, and were deeply interested by the +account given of the imminent danger in which many countries are placed +that purchase breeding stock in the British isles. The theories of +spontaneous origin amuse the learned here not a little, as they justly +think we ought not to be so far behind every nation in the possession of +knowledge regarding the propagation of such a disorder as the steppe +murrain. + + +NOTE E. + +Now, if the disease came from abroad, and diseased cattle were shipped +on the other side of the sea, no doubt the voyage would concentrate and +aggravate the disease. Whether the disease came from abroad or elsewhere +he was not able to state. Sir George Grey asked him whether he had found +any disease among the foreign cattle that came into the market. He had +not one. He could only say they had had no cases, except in cows, +whether they came from the dairies in London or elsewhere. So far as +they knew, not one single bullock or ox had been condemned.--MR. GIBBINS, +_18th August, Meeting at the Mansion House_. + +The very first shed in which the plague must have appeared in London is +a pattern of cleanliness, and the stock was magnificent, as proved by +the animals in a shed to which the disease has not been propagated. +Almost simultaneously the malady broke out in the Essex marshes, and in +every instance we trace a more or less direct contamination by foreign +stock. + + +NOTE F. + + VIENNA, August, 1865. + +On the 28th of August about thirty of the members of the Congress +accepted an invitation to visit the renowned agricultural establishment +at Altenburg, in Hungary. After the visitors had inspected the herds and +other appurtenances of this institution, Professor Maasch, its director, +intimated that the Rinderpest had appeared at Nickolsdorf, about four +German miles from Altenburg. The President of the Congress had known +this fact before the party left Vienna for Hungary; but as he feared +some enthusiasts would first see the plague, and then inspect the +Altenburg herds, he preferred to adopt the stratagem of communicating +the information through Professor Maasch, after the great Agricultural +College of Hungary had been viewed. Nickolsdorf, where the steppe +murrain appeared on the 10th of August, is an exquisitely clean village, +with well-whitewashed buildings and broad roads, constituting the centre +of a thriving agricultural district. Its people are typical Hungarians, +not too anxious to work, and, on the whole, poor; but they are +intelligent, notwithstanding the national proclivity to farm a thousand +acres badly rather than one-fourth the quantity to perfection. Their +wants are not great, and their worldly luxuries, beyond potatoes and +schnaps, are bought with the profits made on large herds of cattle. One +herd only had suffered from the cattle plague when we visited the +village. This herd consisted of 1225 animals, divided into three lots. +The affected portion numbered 450 animals--bullocks intended for work +and slaughter--varying in age from three to seven years. The cows and +heifers had not been smitten. The 450 animals amongst which the disease +appeared were housed in no less than sixteen different sheds in +Nickolsdorf. Out of each of these places sick animals had been taken, +and either slaughtered or permitted to die. We killed four for +dissection on the 29th. Six more had been previously killed, their hides +slacked, and the entire body buried; nine had died, and two we left in +life to be soon slaughtered and disposed of as the others. The district +veterinary surgeon in constant attendance was an extremely active and +intelligent man, who recognised the disease on its first outbreak, and +adopted such measures for separation, destruction, and burial, as +prevented the disease from spreading so rapidly as it has in England. + +The cause of the outbreak was the intermingling of cattle-dealers' stock +with the Nickolsdorf herd; and although the animals which carried it +have not been fully traced, they are believed to have been owned by a +butcher who had purchased them in Comorn, where the malady is raging. +Singular variations have been seen in the symptoms exhibited, especially +when animals are first affected. During the Nickolsdorf outbreak there +has been an invariable incubation of five or six days; then furor or +delirium appears: the bullocks stare, roar, stamp with their feet, are +prepared to attack people who approach them, and seem to be dizzy at +intervals. They shiver, their muscles twitch, the eyes soon begin to +discharge, and the mucus which flows from the mouth foams. The pulse is +at first slower than usual, until all the fever symptoms appear. There +is more constipation than diarrhoea, though, on examination, the +mucous membranes are all found to be affected precisely in the manner so +often observed in England during the present outbreak. The differences +in the symptoms are accounted for by peculiarities of breed, the +condition of stalls, the food the animals have lived on, and similar +circumstances. We may hear more of these Hungarian outbreaks, but the +chances are we shall not witness in any part of Austria the wholesale +devastation now going on in Great Britain.--_International Veterinary +Congress._ + + +NOTE G. + +At present the cowkeepers send off the infected beasts to the market, or +to some slaughter-house, where they might be killed. There was believed +to be great danger in allowing the infected cows to be driven through +the streets. If the good could be separated from the bad animals, and if +the latter could be conveyed to sanitoriums, where the medical men could +operate upon them, then much benefit would result; and then, too, if the +animals died, they would be buried on the spot. All the professors were +agreed in this, that if a compensation fund were raised, and the +cowkeeper were told that he would be remunerated for his loss, he would +at once inform the authorities when the disease made its appearance in +his cowshed. Shed after shed was being now shut up, and men and women +who seemed to be affluent one day were the next reduced to ruin. An +illustration of this would suffice. One day last week a cowkeeper at +Pimlico had 70 or 80 healthy cows. On Wednesday three of them were found +dead. On Thursday 42 of them were sent to the market. Of these 42 three +showed symptoms of the disease, and then the whole of the 42 beasts had +to be slaughtered because of the disease being among the three. The poor +fellow was thus ruined. Last Monday he sent nine more cows to the +market, and these also had to be slaughtered. At present the man was +absolutely out of his mind. Out of his 70 beasts, he had not one left. +Some persons were saying that the disease arose from bad water, bad +ventilation, and bad cowsheds; but in the case of Miss Burdett Coutts, +who had had 40 head of cattle, which were most carefully housed and +attended to--particularly from the moment she heard that the disease was +amongst them--all were gone, with the exception of one cow; so that, +whether it was a want of water or a want of ventilation which in other +cases caused it, this was an instance in which everything was done that +could be done, and yet the plague raged and the mortality +ensued.--MR. GIBBINS, _Meeting at the Mansion House_. + + +NOTE J. + +Yesterday morning Dr. Jarvis, medical officer of St. Matthew's, +Bethnal-green, received information that Mr. Castell, an extensive +purveyor of milk, had lost eighty-four cows during the past week. Other +cowkeepers in this district have also experienced great losses. The +disease has manifested itself with more or less virulence at St. Anne's, +Limehouse; St. John, Hackney: St. Mary-le-Bow, St. George's-in-the-East, +St. John, Wapping; Christ Church, Spitalfields; St. Leonard's, +Shoreditch; St. Mary, Whitechapel; St. Paul's, Shadwell; the hamlet of +Ratcliff, Stoke Newington, Kingsland, and Tottenham. + +Mr. Gibbins, chairman of the Metropolitan Markets Committee, Mr. Rudkin, +a member of the committee, Mr. Tegg, veterinary surgeon to the market, +and Mr. Baldry, clerk to the market, applied to the sitting magistrate +at Clerkenwell Police Court yesterday for summonses against cowkeepers +for sending diseased cows into the market. During the course of the +present week no less than nineteen cows had been seized in the market +and fairs and condemned. The order was asked for under the 8th section +of the recent Order in Council, which recited that it shall not be +lawful to send or bring to any fair or market, or to send or carry by +any railway, or by any ship or vessel coastwise, or to place upon or to +drive along any highway, or the sides thereof, any animal labouring +under disease. The cattle seized had not been examined by a Government +inspector, and no certificate had been given to the owners that they +were fit to be removed. The market authorities wished it to be known +that proceedings would be taken in every case that was brought under +their notice. Mr. Cooke observed that the inspectors had power to seize +and slaughter, or cause to be slaughtered, and to be buried in any +convenient place, any animal labouring under the disease. Had that been +done? Mr. Tegg said that the animals were in some of the cases +slaughtered, and the others would be slaughtered in the course of the +day. The summonses were granted. + +Yesterday, the summonses issued at the instance of Mr. Frederick Thomas +Stanley, a member of the Royal College of Veterinary Surgeons, and one +of the inspectors appointed under the Order in Council, came on for +hearing before Mr. Burcham, magistrate at the Southwark police court. +The summons in the first case was addressed to Thomas Meredith, of the +Flying Horse-yard, Blackman-street, for that the defendant, without the +licence of the said inspector, did unlawfully remove from his premises +some animals labouring under the cattle disease. Mr. Sleigh, instructed +by Mr. Gant, appeared to support the summons; and Mr. W. Edwin for the +defendant. Evidence was given that the defendant had been warned that +the cows were diseased, but that he had removed them notwithstanding. +The further hearing of the case was adjourned, as were also the other +summonses of a like nature. + +In pursuance of powers vested in him by the Manx Legislature, the +governor of the Isle of Man has issued a proclamation prohibiting the +importation of cattle into the island. Tinder the same Act his +Excellency has power to subject all cattle imported into the island to a +five days' quarantine. + + +NOTE K. + +Tracing, as we have done, the sale of infected stock from abroad as far +back as the 19th of June, we find that each week that the disease has +been amongst us a fresh county has been contaminated; and more than that +when we consider that Scotland has not escaped. + + +NOTE L. + +SCOTLAND.--The cattle plague has travelled North to Aberdeenshire, and +has killed a number of animals almost simultaneously on three farms at +many miles distance from one another. The owners of stock in one of the +districts, and the Royal Northern Agricultural Association, are taking, +or resolving to take, sharp and prompt steps to stay the progress of the +disease. The committee of the association having met on Friday, +appointed a committee of inspection, arranged for a public meeting of +persons interested, and favourably entertained the notion of forming a +fund for mutual insurance against the sacrifices and losses which the +extension of the disease might occasion. A meeting of the General +Central Union was also held at Stirling on Friday, and a committee was +appointed to confer on the subject with the directors of the Highland +Society, and report to another meeting to be held next Friday.-- +_Scotsman._ + +The most important communication received to-day is from Scotland. The +malady has undoubtedly broken out near Kelso, on fourteen head of cattle +imported into London and sent north. Twenty-eight animals have been +seized with the disease at Woolwich, and calves from the London market +are said to have taken the malady down to Horsham and Grinstead. + +Information has been received concerning the sale of at least fifty-four +diseased and infected animals in the Metropolitan Cattle Market the 3rd +instant. + + +NOTE M. + +Mr. Charles Panter has, at the request of Earl Granville, drawn up a +statement relative to the health of the cows on a farm hired by his +lordship at Golder's-green, on the Finchley-road. In publishing the +statement, Earl Granville says: "When I left England, a month ago, there +were about 130 milch cows in four sheds. In the two largest and best +managed I found only one cow yesterday (Sept. 4). His Royal Highness the +Duke of Coburg informed me last week that what he believed to be the +same disease visited Coburg last year. No one could trace its origin, +and no medical treatment was successful. Air and water were their only +remedies. Some men had died from eating the meat killed at a particular +stage of the disease. His Royal Highness had seen a horse die in four +hours, killed by flies which came from the carcase of a cow which had +been allowed to remain above ground. The disease disappeared in the +autumn as mysteriously as it had come. I understand that Professor +Simonds is of opinion that the disease mentioned by the Duke of Coburg +is not the same as that from which we are suffering here--that its name +is the Siberian Pest." Mr. Panter's statement is dated Sept. 4, and is +as follows:--"On the 13th of July I purchased five Dutch cows in the +Metropolitan Market, and placed them in quarantine at Child's-hill Farm, +one mile from here. On the 22nd of July one of them showed signs of +debility; diarrhoea followed. Thinking it was only a cold, she was +treated accordingly, but continued to get worse, and died in five days. +Two more were attacked in a similar way, when veterinary advice was +called in, but in five days the whole either died or were slaughtered. +Every precaution was used to prevent the spread of infection here; the +men who attended the sick cattle were not allowed to go among the +healthy ones, and _vice versâ_. But, previous to this, bearing of the +disease in the London cowsheds, I adopted precautionary measures, such +as a liberal use daily of chloride of lime, administered one ounce of +nitre in half a pint of water to each cow, and a small quantity of tar, +and painted their noses with tar. But on the 8th of August, +unfortunately, the disease showed itself here in a fat cow that had been +for ten months in the best built, best drained and ventilated shed. No +new stock had been added for nine weeks. In a few hours four more cows +showed symptoms of it. I immediately had them all removed and +slaughtered, and made a _post-mortem_ examination of them, and found the +windpipe in a state of decomposition, the lungs inflated, the small +intestines red and inflamed, and the meat of a dark yellow colour +outside, and dark red inside, which I think unfit for human food after +the first stage. The disease confined itself to the above shed of +forty-eight cows (which are now all gone) till the 20th of August, when +it broke out in another shed of thirty-five cows, some ten yards from +the former one, and continued its ravages, taking from two to four cows +daily, till they are all gone but two, one of which has not been +attacked; the other, which was a bad case, is cured, and partly come to +her milk again. On the first symptoms I had her separated from the other +stock, and did not treat her for two days, when diarrhoea set in; I +then gave her a bottle of brandy and four ounces of ground ginger in +three quarts of old ale. She lay in a kind of stupor for twelve hours, +when I could see a change in her for the better. I continued to give her +daily four quarts of gruel made with old ale and two ounces of ginger. +In four days she was sufficiently recovered to eat a little hay, &c., +and do without further treatment. In another case the above treatment +failed, and the animal died in three days. In other cases I allowed +anyone to treat them who thought they had a remedy, both professional +men and others. One persevering young veterinary surgeon came up out of +Somersetshire and treated two cases most energetically, but failed in +both; one died in four, and the other in eight days. In other cases +tonics, stimulants, blisters, and setons have been tried, but all +failed. The whole of the eighty-one cows lost were of the English breed; +we have not as yet had any loss out of the other two sheds, consisting +of about half English and half Dutch cows, and standing about forty +yards from the infected shed. It may be interesting for your lordship +to know that I had the shed at Child's-hill Farm immediately cleansed +with disinfectants, and washed with hot lime, &c., and bought twelve +fresh cows and placed them there on the 16th, which are now in perfect +health; and a neighbour situated midway between here and that farm had +twenty-three cows lying in a field; the plague took twenty of them, and +in three weeks he replaced them with new stock, which are still healthy, +he having had them a month. Another neighbour, a mile distant, had a +fine herd of seventy-two cows (English) lying in the fields a fortnight +ago. The plague broke out among them, and now he has only eight left in +health. From my own experience, and from all I can learn, I believe the +disease is atmospheric, and of a typhoid character. The first symptom in +a milking cow is an almost entire loss of milk, then loss of appetite, a +watery discharge from the eyes, nostrils, and mouth, which thickens as +the disease develops itself; rumination ceases, her ears hang down, her +eyes are heavy and sunken, bloody matter is seen in the excrement, great +debility is seen, diarrhoea sets in, and death takes place in from +three to nine days. I have read of iron water being a preventive of the +disease. All the water your cows have drunk comes six miles through +rusty iron pipes." + + +NOTE N. + +THE CATTLE MURRAIN AT HOLLY LODGE.--On the 27th of June an +Alderney bull was purchased at Bushey, near Watford, and placed with the +rest of the herd, then consisting of eleven cows, five sucking calves, +three yearling heifers, and one bull. The bull had been imported from +Alderney for several months. About a month after--namely, on the 29th of +July--a cow in calf was attacked with unusual symptoms. She was +separated from the rest; nourishing drinks were administered; but having +calved, she died forty-eight hours after the first symptoms were +observed. This led to the belief that she died of the disease which then +began to prevail. This cow had been pastured with the others in a field +occasionally used for grazing sheep that were taken to the Metropolitan +Cattle-market, and, if not sold, brought back again until the next +market day; the sheep were separated from the cows by iron hurdles. The +Holly Lodge Estate is partly bounded on the east by the route taken by +drovers with foreign and other cattle to and from the market, some of +which are also occasionally brought back to neighbouring fields. The +high road forms the western boundary within a few yards of the +cattle-sheds and pastures. These facts are stated to show that the +contagion might have been easily communicated to the animals. A few days +later three calves were attacked with cold shivering and twitching of +the muscles. The previous nights having become suddenly and unusually +cold and wet, the symptoms were at first attributed to that cause. +Although these calves had been pastured quite apart from the cow which +first died, the cow had been driven across the field where the calves +lay to the shed in which it died, the calves having been placed in the +next shed, where two of them died on the 6th of August, unmistakeably +of the cattle plague. The third calf was sent to the Royal Veterinary +College, where it also died. By the 9th of August four cows and the bull +were seized with the disease so virulently that it was thought necessary +to kill them after three days' illness. On the 12th a cow and a heifer +were also destroyed, and on the 14th one of the sucking calves died. +Thus, out of a herd of nineteen animals, twelve had died within a +fortnight. The malady had taken so strong and sudden a hold upon them +that no systematic means of remedy could be applied except separation, +warmth, stimulants, and the medicines ordinarily given in cases of cold +and fever. On the 13th of August two more cows were pronounced incurable +by two of the veterinary surgeons who had been called in; but it was +determined, upon further advice, to try a mode of treatment upon them +not hitherto adopted. One drachm of calomel was administered in gruel, +four hours afterwards one pint of castor oil, and three hours later one +quart of yeast. About two quarts of warm porter were added to a gruel of +yeast and oatmeal, and given at intervals. These remedies acted most +efficiently, and in one case gave much encouragement. The next day the +cow began to eat hay, to chew her cud, and to yield a good quantity of +milk. These remedies, together with bi-sulphate of soda, which +invariably produced a return of the milk, and quinine, were then tried +upon four other patients, with varied success. But in the end all these +cows died, not, it is believed, of the cattle murrain, but of exhaustion +occasioned by the activity of the drugs administered to them. This +belief was strengthened by the healthy appearance presented by the +viscera of the first cow thus experimented upon, on its being partially +dissected after death. The remaining cow thus treated is still alive. It +is impossible to avoid believing that had the medical man who kindly +gave his attention to these animals, been better acquainted with the +constitution of the creature, or had those who tended them had any +knowledge of medicine, three of the cows treated in this manner might +and probably would have recovered; and even when the animals succumbed +the consequences were less serious, the virulence of the poison being +expelled--at least it was undiscernible to those who dissected them. +During the fortnight that the murrain was raging, one cow in calf and +one calf remained perfectly healthy, apparently, until both were seized +within a day of each other; these had always been kept separate from the +sick animals, and tended by other men. The calf died, and the cow was +destroyed, in consequence of the symptoms being so violent. In this case +very little calomel was given. As it may be as well to mention all +particulars, it may be stated here that the men who tended the animals +were provided with a dress, and that it was found desirable that a +certain quantity of stimulants--brandy, coffee, and strong soup--should +be given to prevent nausea and other uncomfortable feelings from which +the men suffered. All the directions respecting the burying of the +animals issued by the Privy Council have been strictly complied with; +clothes, &c., have been burnt, chloride of lime (Macdougall's +disinfectant) was used with others to destroy insects and flies, with +abundance of white-washing. The men were recommended to use, as a wash +for the mouth, manganate of potash. The first crop of grass in the field +where the cattle lay before their sickness, and during it, has been +destroyed also; and it is intended to use some disinfectant, such as +charcoal or lime, to spread over the field. Miss B. C. feels so +persuaded that some mode of treatment could be found to alleviate, if +not to save life, that she has determined to employ a medical gentleman, +who kindly offers his services, and to take also the advice of a good +cow or veterinary surgeon, and to try the effects of various remedies in +some of the cowsheds where persons will be glad to let such experiments +be tried; and it is also her intention to ask the Privy Council to allow +one of the Government Inspectors to assist and report upon the cases. It +may not be altogether unimportant to add that the state of the +atmosphere seemed to have some effect upon the health of the animals, as +upon those occasions the symptoms were most severe during the +thunder-storms which then occurred. The milk which returned was found to +be rather watery, and the cream had a peculiar appearance. At first the +pigs declined it, and it was not thought advisable to continue to give +it at all to any animals for about a week. It is now perfectly good. + + +NOTE O. + +Advices from Holland, dated the Hague, Sept. 6, state: "The cattle +disease has now been observed in the parishes of Kethel, Delfshaven, +Moordrecht, Uaardingen, Averschie, Kvalingen, Nieuwerkerk on the Issel +(two hours from Rotterdam), Spykenisse, Schiedam, Herrjansdam, Maasland, +Sommelsdyk, and Zevenhuisen. It has spread most at Kethel, where it +first broke out among a cargo of cattle not admitted into England. In +the other parishes some sixty animals were infected on the 1st inst. The +post-mortem examination of the diseased beasts presents the abnormal +appearances that have been found in the disease elsewhere, _i.e._, +swollen mucous membranes with red spots, peculiar exudations in the +fourth stomach and intestines, &c. The medical commission declares the +malady to be the _typhus contagiosus bovum_ of modern veterinary +surgery, and recommends that infected animals should be treated with +from three to four drachms of muriatic acid, mixed with six ounces of +treacle and decoction of linseed. Decoctions of Peruvian bark and osier +peelings, with sulphuric ether, are also said to be beneficial to weak +animals. The avoidance of all contact of the cattle-tenders with +infected beasts is especially enjoined, and ventilation and cleanliness +of the stalls strongly recommended. Cattle markets and fairs are +suspended until further orders, and extraordinary measures for +disinfection are applied upon steamboats and railways." + + +NOTE P. + +The following document has been received at the Foreign Office from her +Majesty's Agent and Consul-General at Bucharest:-- + +(_Translation from the Official "Monitoral," No. 173, August 8-20, +1865._) + +GENERAL DIRECTION OF THE SANITARY SERVICE. + +From the 1st to the 15th July a typhus epizooty broke out among the +large horned cattle in the districts of Ilfov, Jassy, Bolgrad, Falcin, +Buzeo, and Roman, which still continues, but is on the decrease. The +Direction, in consequence, publishes the above for the information of +those concerned. + + The Director-General, + + (Signed) D. GLUCH. + + Aug. 2-14, 1865. + + +NOTE R. + +August 14. + +THE QUESTION OF INFECTION.--Yesterday afternoon Mr. Alfred +Ebsworth, of 11, Trinity-street, Southwark, the medical officer of +health for the parish of St. Mary, Newington, attended before the +sitting magistrate to make a statement with regard to the condition of +the parish from the influx of diseased cattle, and the manner in which +they were disposed of. Addressing the magistrate (Mr. Burnham) Mr. +Ebsworth said that on that morning he, in his capacity of medical +officer of health for the parish of St. Mary, Newington, received an +order to attend professionally a man who was seriously ill in +Kent-street, within the parish. While paying the visit to the patient +his attention had been drawn to the condition of a slaughter-house on +the other side of the street, where it was reported to him there were +fifteen cows which had been ordered by the Government officer to be +destroyed at the Bricklayers' Arms Station, and then to be buried. The +animals were accordingly destroyed by the men in the employ of Mr. +George Nicholls, the proprietor of the yard in question; and from Mr. +Nicholls he had learned that, instead of the carcases of the animals +being buried, they were carted through the parish of St. George's to +Mitcham, where they were boiled down, and brought back through the +parish of St. Mary, Newington, in the shape of cats'-meat. He (Mr. +Ebsworth) felt it his duty to come before the magistrate with this +complaint, especially when the cattle plague was so prevalent. He had a +right to inquire upon what grounds the carcases had not been disposed of +on the spot where they had been slaughtered, instead of being carted +through the parish he represented, in a way calculated to spread the +infection. He could not but regard this as a most iniquitous proceeding, +and he attended with a view to prevent a repetition of the practice. Mr. +Frederick T. Stanley presented himself, and said that he was a member of +the Royal College of Veterinary Surgeons. He had been appointed an +inspector of cattle under the orders issued by the Privy Council. Within +the district there were no means of burying the carcases of the diseased +and condemned animals, and in the instance referred to they could not +have been buried in the cowshed. It was impossible to bury the carcases +in the London districts, and hence they were sent to the knacker's yard, +where it was supposed they would be disposed of. Mr. Ebsworth: And +that, your worship, is what I complain of. Mr. Burcham: You think that +the practice to which you have called my attention is calculated to +propagate the extension of the disease. Mr. Stanley declared that the +skins were disinfected under his especial orders. Mr. Burcham remarked +that the animals had been taken to the slaughter-house, not for the +purpose of being killed and buried, but that their skins should be taken +off and disinfected. Why should they have been taken to Mitcham? Mr. +Stanley stated that the disease could not be communicated from a dead +animal, and it was conveyed only by inoculation, or through the breath +of a living animal upon the dead body of a diseased ox. Mr. Burcham: I +do not agree with you in that opinion. I believe that infection may be +conveyed by a dead animal. Mr. Ebsworth said that such was his opinion, +and, having regard to 28,000 patients in the parish, he had felt it his +bounden duty to come forward to make this complaint. He thought such +things ought not to occur. Mr. Burcham was of the same opinion, and that +such a commodity ought not to be allowed to be conveyed through the +public streets in open carts. Just before the magistrate was about to +rise, Mr. Stanley introduced to his worship Professor Simonds, and a +long colloquy (in private) ensued between them. At its close Professor +Simonds retired, and Mr. Burcham said: I wish to state that I wanted to +be satisfied that everything was done by Mr. Stanley that could be done +under the circumstances by which he was surrounded, in the midst of +great difficulty. I have had an interview with Professor Simonds, and he +informs me that there are the greatest difficulties, if not +impossibilities, in finding any places near London in which the dead +carcases of diseased animals can be buried. In the case now before me +these animals were slaughtered at the Bricklayers' Arms Station, and +were then taken to the slaughter-house in Kent-street, under the notion +that the owner of the slaughter-house had the means of boiling them +down. It appears that he had no such apparatus, and hence he found it +necessary to send the carcases to Mitcham, the nearest place at which he +believed the carcases could be buried and disposed of, and the +neighbourhood thereby disinfected. Professor Simonds is perfectly sure +that this meat when boiled down cannot by any probability cause the +infection to spread. It was possible, but not probable, that infection +might be introduced by the carcases of the diseased animals on their way +to the place where they had to be boiled down; but it appears to me, +from what I have just heard, that every precaution has been taken to +prevent such an occurrence. It seems that the authorities cannot find a +place within a reasonable distance in which the carcases can be buried, +and, therefore, they are obliged to have recourse to boiling them down, +as the only alternative. It is right that I should add that the conduct +of Mr. Stanley, the inspector, has been quite in conformity with the +directions he has received, not only under the Orders in Council, but +also sanctioned in my presence to-day by Professor Simonds. I trust that +this statement will remove from the mind of Mr. Stanley any unfavourable +impression he may have entertained; and I will only add my opinion, that +the diseased cattle ought to be removed through these populous +districts in closed and not in open carts. The conversation then closed, +and at an unusually late hour the court adjourned. + +DISEASED MEAT.--At the Thames Police Court yesterday Henry +Frost, an old man, was charged with having allowed to be deposited on +the premises occupied by him in the rear of the house, No. 13, +Sidney-street, Stepney, four quarters of beef prepared for sale and +intended for the food of man, but which was unfit for human food. Frost +carried on the business of a greengrocer. He asserted that he let the +place to other men, who were the actual offenders. It was intimated that +the vestry had no disposition to press for a heavy penalty. Mr. Paget +fined the prisoner 40s. At Clerkenwell, Mr. Tegg, inspector at the +Metropolitan Cattle Market for the City authorities applied to Mr. +D'Eyncourt for an order to destroy a quantity of diseased meat which he +purposed seizing. Mr. D'Eyncourt said the meat must be actually seized +and condemned upon evidence before he could make the order. In the +matter of the seizure of 32 quarters of beef, weighing about 3000 lbs., +which was found on the premises of a knacker in Pleasant-grove, +Belle-isle, Mr. D'Eyncourt dismissed an application made against the +defendant under the Nuisances Removal Act. The defence set up was that +the meat was recognised as bad and diseased by the killer as soon as the +animals were slaughtered. + + +NOTE S. + +The Orders in Council seemed only to complicate the matter, and how +effectually to combat the evil was a most difficult question. Some said +the grand remedy was the knife, and others suggested that the diseased +animals should be sent to a sanatorium. To destroy the diseased cattle +was impossible, except the owner of them or the inspector went round and +obtained an order from a magistrate for their destruction. The last +meeting was adjourned, among other purposes, in order that the committee +might take the opinion of the law officers upon the subject. It so +happened, however, that most of the law officers of the Corporation were +at present out of town. Fortunately the Common Serjeant was found, and +he gave an opinion which confirmed the committee in their view that they +had no power to kill, and no power to do anything except in the matter +of isolation. Then the committee passed a resolution that another +committee ought to be formed to raise the necessary funds for +compensating the cattle-owners, and to see that those funds were +properly applied, for the money was only intended to apply to the cattle +plague, and was not meant to go in the shape of compensation for +pleuro-pneumonia, or for the foot diseases. In other words, they were +now legislating for the cattle plague or Rinderpest only. He resided at +Dulwich, and he found that in the villages adjoining there were many +cows, and never in his life had he seen finer cows. Not one of them had +been affected by the disease. There was a cowkeeper at Peckham who had +200 cows, and all of them were in the most healthy state. At Brixton +Hill a man had 30 cows in the same excellent condition. At Dulwich +nearly all the cows were diseased, but there the shed and other +accommodation was exceedingly bad. In parts of Peckham Rye some of the +cowkeepers had lost their cattle, but there again the places were badly +ventilated, and the cows were badly cared for. He believed that the +disease might be prevented by the use of proper precautions on the part +of those who had the greatest interest in keeping their cows in a +healthy state. He believed, too, that this question affected the whole +of the metropolitan district quite as much as it did the City itself. +There were no fewer than 106 head of diseased cattle lately seized; but, +as he said before, they could not be killed without an order from a +magistrate, and a magistrate would naturally feel a difficulty in +issuing an order to kill so many as 106 head. It was necessary, under +such circumstances, that a deputation should wait upon the Home +Secretary and ask him to provide a remedy, and tell the authorities what +they were to do at such a crisis. If, as it now appeared, the inspectors +and the markets' committee had been slaughtering beasts without +authority, who was to pay the costs should proceedings against them be +commenced? Professor Simonds seemed to think that next session a bill of +indemnity would be introduced, and certainly something of this kind was +rendered necessary, for cattle were now coming here which were consigned +to A., B., and C., and then the owners could not be found, and without +the consent of the owners the diseased beasts could not be killed. The +next subject in the report had reference to slaughter-houses. As there +were no places at present to which cattle in an incipient stage of the +disease could be removed from the sheds in which they were placed along +with untainted cattle, it was now proposed that slaughter-houses should +be established in London for their reception. Then came the question, +how were the beasts to be removed from the sheds to the +slaughter-houses? It was the opinion of many that they ought to be +removed in vans, and not driven through the streets; but, however that +might be, slaughter-houses should be erected in the metropolis where the +tainted animals might be killed. Then came the question, how was an +animal to be dealt with when first stricken with the disease? It was +suggested that hospitals or sanatoriums should be provided, to which the +beasts should be sent. But this was a matter of great importance, to +which the attention of the committee to be appointed and that of the +medical men would have to be directed. If the plague went on it would +affect all classes, rich and poor alike, and instead of meat being as +now at a reasonable rate, it would go up 4_d._ or 6_d._ per pound; but +he had hopes that the disease might be checked, particularly as +Professors Simonds and Gamgee had been more successful in the treatment +of it than they had previously been. + + +NOTE T. + +August 31. + +DEPUTATION TO THE HOME OFFICE.--Yesterday afternoon the Lord +Mayor proceeded from the Mansion House to the Home Office, and had an +interview with Mr. Waddington on the subject of the cattle plague, and +the desirability of establishing hospitals or sanatoriums within the +metropolitan districts for the reception and medical treatment of +diseased cattle. His lordship was accompanied on the occasion by the +following deputation from the Markets and Cattle Plague Committees:--Mr. +Gibbins (Chairman of the Markets Committee), Mr. Webber, Mr. Gower, Mr. +Brewster, Mr. Rudkin, and Dr. Jarvis (the Medical Officer of Health for +Bethnal-green). Sir George Grey having left London for Falloden. + +The Lord Mayor introduced the deputation to Mr. Waddington, and in doing +so, said that their object was to obtain the sanction of Government to +the establishment of hospitals or sanatoriums within the metropolitan +districts, to which diseased cattle could be conveyed from the cowsheds +in order that they might there receive medical treatment, and be, if +possible, restored to health. He observed that similar establishments +had been formed at Edinburgh and other large towns, and that they had +been found to work most satisfactorily, not only in separating the +diseased cattle from those which were non-diseased, but in affording +facilities to the medical profession to exercise their skill and +knowledge under circumstances more favourable to a fair trial of both +than they could expect to find in crowded cowsheds, many of which were +in a filthy condition and badly ventilated. He pointed out the progress +the plague had made, and was still making, in the metropolis, and how +its effects upon the high price of meat and milk were affecting all +classes of the community. The difficulties, he said, of adequately +meeting the necessities of the case were at present very great, and some +of these consisted in the alleged illegality of slaughtering diseased +animals without an order from a magistrate, and also the illegality of +removing those diseased from the cowsheds to the hospitals, supposing +the latter to exist. But he hoped the Government, who had no doubt well +considered a subject of such vast importance, would speedily do away +with those difficulties, and render the fullest aid to the Markets' +Committee and Metropolitan Cattle Plague Committee, who were unceasingly +devoting their time and attention to mitigate, and, if possible, put an +end to the evil. At present, however, the object of the deputation was +limited to that of obtaining the sanction of the Government to the +establishment of the hospitals or sanatoriums. This was an object which +had not only received the general approval of the two committees +mentioned, but also of the medical profession, and he might add, what it +was by no means unimportant to bear in mind, that the cowkeepers +themselves and the salesmen of the Cattle Market were also in favour of +it. + +Mr. Gibbins and the several members of the deputation corroborated what +had fallen from the Lord Mayor, and strongly advocated the necessity of +having the hospitals speedily established. + +Mr. Rudkin called the attention of Mr. Waddington to the fact that the +day before there were fourteen diseased cows seized at the +slaughter-house of the Cattle Market, which had been sent there from the +cowsheds of the metropolis. He argued that this in itself was a proof +that the Order in Council, as at present carried out, was insufficient +to prevent diseased cows from being sent from the cowsheds by their +owners to be slaughtered for human food. + +Mr. Waddington, who listened very attentively to the whole of the +statements, said he would take an early opportunity of communicating +with Sir George Grey upon the subject. In the first instance, however, +he wished the deputation to forward to him their views in writing, and +these also would be transmitted to the Home Secretary. + +The deputation promised to comply with the suggestion, and thanked Mr. +Waddington for the courtesy with which he had received and the patience +with which he had listened to them. + +YORKSHIRE.--The plague has extended to this district. The cases +reported, however, are extremely few, and precautions are being taken +which it is hoped may stop the further progress of the disease. On +Tuesday a meeting of the Yorkshire Medical Veterinary Society was held +at Leeds, and the question was discussed in all its bearings. It was +stated that four cases had occurred in Leeds, and the disease has also +appeared in the Skyrack division of the Riding. The general result of +the discussion was, that members of the society were recommended, when +diseased cattle were submitted, not to order them to be killed, but to +place them in a sanatorium for medicinal treatment; the wholesale +destruction of the animals being regarded as a blot upon the profession. + + +NOTE V. + +Indeed, information has reached us of the disease existing in +Dumfriesshire, but there is some doubt on this point. So long as we hear +of infected, or probably infected, cattle being disseminated in large +numbers from the great markets of the country, we must have the +propagation of the malady. For the welfare of this country, it is deeply +to be regretted that our Government cannot deal with this question as +Continental authorities do. _I regret to say some of our neighbours +laugh at our expense._ They see us helpless owing to the wretched state +of our laws on the subject, and they are not a little amused at the +theories of spontaneous development of the disease which some still +advocate. The French Emperor has sent over Professor Bouley, who is +still in this country, and who telegraphed on his first arrival, about +ten days ago, that the ports of France should be instantly closed to +British cattle. This has been done, and we may depend upon it the French +people will not suffer as we now must.--GAMGEE, _Lettre du 24 Août_. + + +NOTE Y. + +August 16. + +MORE SEIZURES OF DISEASED MEAT.--Yesterday Mr. Paget, in the +course of the proceedings at the Thames Police Court, was informed that +there was a large quantity of meat in a van in the police-yard +adjoining, which had been seized that day by Mr. J. Stevens, the +sanitary inspector of Mile-end Old Town, and which was described as +unfit for human food. The inspector stated, that in consequence of +having been informed that there was a quantity of diseased meat at the +shop of Mr. Frost, butcher, Sydney-street, Mile-end Old Town, he went +there that morning, and found four quarters of beef (two fore and two +hind quarters) which were from a diseased beast. He made a seizure of +them, and heard that the animal had been sent by a person of the name of +Stephens, a cowkeeper in business on Bow-common. The meat was in a very +nasty state, and totally unfit for human food. (Mr. Paget went into the +police-yard to examine the meat, which was in a very shocking state.) +Dr. Freeman, Medical Officer of Health of the Hamlet of Mile-end Old +Town, stated that his attention was called to the state of the meat by +the sanitary inspector. He examined it, and gave his opinion that it +should be destroyed, as it was not only in a diseased condition, but he +believed that it had died from some disease. Mr. Paget: Can you state +the nature of the disease which caused its death?--Witness: I cannot. +Most likely it was the prevailing epidemic; and if it were eaten it +would be very injurious. Mr. Paget, after hearing the evidence, ordered +that the meat should be immediately destroyed, when the inspector took +the van with its contents to a knacker's yard to see the order carried +into effect. + + +NOTE Z. + +NEFARIOUS ATTEMPT TO SPREAD THE PLAGUE.--Yesterday Mr. Gifford, +Sanitary Inspector to the parish of Paddington, asked (at Marylebone +Police Court) for the magistrate's advice under the following +circumstances:--Applicant said that, in consequence of information +received, he yesterday went to a cowshed situate on the Maryland Farm, +Harrow-road. He found the door fastened. On looking through one of the +chinks, he saw a cow which apparently was in the worst stage of the now +prevailing disease, and his opinion was verified after he had burst open +the door and examined the animal. He subsequently ascertained that the +diseased cow had been brought some distance by a man who was at feud +with the owner of the Maryland Farm, and surreptitiously placed amongst +the healthy cattle. This was the first case where the disease had shown +itself in the parish of Paddington. Mr. Yardley referred the applicant +to the Order in Council, dated the 24th of July, 1865, under which he +thought inspectors of nuisances had power to act summarily. + + +THE END. + + + LONDON: + SAVILL AND EDWARDS, PRINTERS, CHANDOS STREET, + COVENT GARDEN. + + + + + +-----------------------------------------------+ + | Transcriber's Note: | + | | + | Inconsistent hyphenation and spelling in the | + | original document have been preserved. | + | | + | Greek words are transliterated and marked | + | +like so+ | + | | + | Typographical errors corrected in the text: | + | | + | Page 62 Ge11e changed to Gellé | + | Page 67 Bruneleschi changed to Brunelleschi | + | Page 142 Röol changed to Röll | + | Page 175 charboneux changed to charbonneux | + | Page 253 eat changed to ate | + | Page 354 lairs changed to fairs | + | Page 377 Boulay changed to Bouley | + +-----------------------------------------------+ + + + + + +End of the Project Gutenberg EBook of On the cattle plague: or, Contagious +typhus in horned cattle. 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Thus, we do not necessarily +keep eBooks in compliance with any particular paper edition. + + +Most people start at our Web site which has the main PG search facility: + + https://www.gutenberg.org + +This Web site includes information about Project Gutenberg-tm, +including how to make donations to the Project Gutenberg Literary +Archive Foundation, how to help produce our new eBooks, and how to +subscribe to our email newsletter to hear about new eBooks. diff --git a/36496-0.zip b/36496-0.zip Binary files differnew file mode 100644 index 0000000..7a2cd57 --- /dev/null +++ b/36496-0.zip diff --git a/36496-8.txt b/36496-8.txt new file mode 100644 index 0000000..7f66835 --- /dev/null +++ b/36496-8.txt @@ -0,0 +1,8825 @@ +The Project Gutenberg EBook of On the cattle plague: or, Contagious typhus +in horned cattle. Its history, origin, description, and treatment, by Honoré Bourguignon + +This eBook is for the use of anyone anywhere at no cost and with +almost no restrictions whatsoever. You may copy it, give it away or +re-use it under the terms of the Project Gutenberg License included +with this eBook or online at www.gutenberg.org + + +Title: On the cattle plague: or, Contagious typhus in horned cattle. Its history, origin, description, and treatment + +Author: Honoré Bourguignon + +Release Date: June 22, 2011 [EBook #36496] + +Language: English + +Character set encoding: ISO-8859-1 + +*** START OF THIS PROJECT GUTENBERG EBOOK ON THE CATTLE PLAGUE *** + + + + +Produced by Barbara Kosker, Bryan Ness and the Online +Distributed Proofreading Team at https://www.pgdp.net + + + + + + + +-----------------------------------------------+ + | Transcriber's Note: | + | | + | Inconsistent hyphenation and spelling in the | + | original document have been preserved. | + | | + | Greek words are transliterated and marked | + | +like so+. | + | | + +-----------------------------------------------+ + + + + + ON THE + CATTLE PLAGUE: + OR, + Contagious Typhus in Horned Cattle. + + ITS HISTORY, ORIGIN, DESCRIPTION, AND TREATMENT. + + + + + BY + H. BOURGUIGNON, + + Doctor of the Faculté de Paris, Fellow of the Société de Médecine + de Paris; Laureate of the Institute of France, Member of the + Legion of Honour, etc. + + + + + "Scribo nec ficta, nee picta, sed quæ ratio, + sensus et experientia docent." + + + + + PHILADELPHIA: + J. B. LIPPINCOTT & CO. + LONDON: J CHURCHILL & SONS. + 1869. + + + + + TO + MISS BURDETT COUTTS. + + + MADAM, + +The numerous services which you have rendered, and the interest you have +shown in the calamitous epizootic which at this moment decimates the +noble herds of England, have prompted me to dedicate the following pages +to you, satisfied that I am only giving public expression to the homage +felt for you by many of your fellow-countrymen. + +I have the honour to be, Madam, + + With respect, your obedient servant, + + H. BOURGUIGNON. + + + + +PREFACE. + + +Nations, during the successive phases of their evolution on the globe, +in which they advance from a state of infancy and barbarism to one of +virility and civilization, from civilization to decadence or senility; +and from decadence to their final extinction, are liable to numberless +calamities. + +These calamities are produced by moral causes, and are then called +social Revolutions; and in other instances from physical causes, and +then they are termed Cataclysms, Epidemics, or Epizootics. + +In these crises, the initiative and devotion of individuals, the public +administration, and the application of knowledge acquired in the Arts +and Sciences, afford collectively an infallible criterion for +ascertaining the position which a nation occupies in the scale of +civilization, and the value of its religious, social, and political +institutions. + +Calamities always leave behind them disasters and victims, but they +bequeath also a precious legacy. Nations which are called upon for fresh +and progressive efforts, find in the experience they have gained a new +source of strength and means of future greatness. I am convinced that +this will be the case with England; though, helpless for the moment, and +unable to stay the Cattle Plague which now ravages her entire extent, +she will in future be found better prepared to resist the inroads of +such a direful enemy. + +No branch of human knowledge has been more rudely tested during the +present epizootic than medical science. Many persons have been astounded +at its helplessness; but if they had reflected at what a distance +medicine has to follow in the wake of the exact sciences by which it is +furnished with instruments for prosecuting its researches,--that +organic chemistry progresses but slowly,--that the Cattle Plague was +entirely unknown to the present generation of medical men in +England,--and that the means for its scientific and practical study have +been therefore wholly wanting, they would have been less surprised to +find that it is as difficult to cure the Cattle Plague as it, is to cure +phthisis, cancer, hydrophobia, and the cholera, against which medicine +but too often is of little avail. + +In times of great national calamity it behoves every one to contribute +in proportion to his talents, fortune, or abilities, to alleviate the +effects of the common misfortune. The poor man's mite, and the honest +intention of the most insignificant, when added to the budget of common +efforts, have their relative value; and it is for these reasons that I +have published the following monograph on the Cattle Plague. + +If it assists in any way to the extinction of the present epizootic, or +if it serve to point out the necessity of combining the study of +comparative pathology with that of medicine, I shall feel that I have +contributed something which may favour my claim to be enrolled among the +citizens of England. + +This book, as may easily be seen, was originally written in my native +language. A few kind and obliging friends--more particularly Mr. Taylor +Sinnett, Drs. Clapton and Gervis, of St. Thomas's Hospital, and Mr. +Berridge, of the British Museum--have rendered me the greatest +assistance in the translation. Without the guidance of such competent +auxiliaries I could not have performed my arduous task. + +I therefore beg to return to those gentlemen, and to all those who have +assisted me on this occasion, my sincerest and most grateful thanks. + + H. B. + + + + +CONTENTS. + + + PAGE + + Introduction 1 + + + FIRST PART. + + The History of the Contagious Typhus of the Ox, from + the remotest Times down to the Present Day 5 + + + SECOND PART. + + CHAPTER I.--On Typhus Disease in general, and the + Typhus which affects the Ox in particular 72 + + CHAPTER II.--The Origin and Causes of the Ox-Typhus 84 + + CHAPTER III.--Description of the Contagious Typhus + of the Ox; its Symptoms, Course, Progress, &c. 140 + 1. Symptomatic Characteristics 141 + 2. Lesions found in the Bodies after Death 163 + 3. Diagnosis--Prognosis--Use of the Flesh of + Animals--Danger of direct Absorption 173 + 4. General Considerations on the Typhus, and + Recapitulation of the Symptoms 191 + + CHAPTER IV.--Treatment of the Ox-Typhus 206 + 1 & 2. Means and Measures to be employed + to resist the Causes of Contagious Typhus + of the Bovine Species 208 + 3. Curative Medication 237 + 4. Hygienic Measures to be taken against the + Extension of the Contagion--Acts and + Orders concerning sanitary Police Regulations 257 + + + THIRD PART. + + To Farmers and Graziers 281 + + + FOURTH PART. + + Suggestions on the Improvements to be effected in + the Study of Medical Science, in order that we + may be in a Condition to confront Disease generally, + and Epizootic and Epidemic Diseases in particular 311 + + + APPENDIX. + + Various Documents 337 + + + + +INTRODUCTION. + + +Everyone is talking of the CATTLE PLAGUE! But why should we +borrow this sinister and gloomy denomination from the middle ages and +from the people's vocabulary? Is this, then, an unknown and incurable +disease? Is this the first time that it has made its appearance on the +soil of Great Britain? To judge by the manner in which the diffusion of +this complaint has been met, accounted for, explained, and discussed, +one might imagine it was so; and yet the mere observation of its causes, +its symptoms, and its signs and effects on the bodies of the diseased +animals, besides a few references to the medical library, would easily +have testified that nature did not wait until the second half of the +19th century to generate a new distemper. No! Nothing new has appeared +for a long time in the worlds of space. The cosmic phenomena pursue +their perpetual course, and the organic phenomena, _à fortiori_, do the +same. Life, throughout the whole range of the animal kingdom, whatever +may be its changes and fluctuations, submits to the fixed and invariable +laws which hold dominion over health and disease. Our presumption and +ignorance alone can account for the astonishment we manifest, not only +when we witness great general calamities, but even when we look upon +those simple morbid derangements which organic matter, both animal and +vegetable, is continually undergoing on the globe, in the natural +progress of destruction and dissolution. + +The habit we most of us have contracted of confining our observations to +the phenomena which strike our eyes, instead of fixing them on the +general causes by which these phenomena have been produced; the +forgetfulness of some, in others the want of acquaintance with general +and comparative pathology, have in this instance led many conscientious +inquirers to misapprehend both the nature and the treatment of the +cattle complaint. It is in vain that we have subdivided and classed +medical science--in vain that we have arbitrarily instituted a +veterinary medicine and a human medicine; nature, in her acts, has no +such subtleties. With nature, organic matter is organic matter, life is +life; and although it may be true that both organic matter and life +become more complex, and continue to rise in perfection till they reach +man, it is quite as true that the laws of pathology and physiology are +the same in all, and that it is just as difficult to cure the typhus of +the ox as that of man. As, therefore, it is because we overlooked these +fundamental truths, that the outbreak of the cattle distemper found us +unprepared, we must treat the subject with all the gravity which is its +due. + +Let it not, however, be feared that the special fact of the _so-called_ +Cattle Plague will be lost sight of amidst a crowd of scientific +generalities. No; collateral reflections, seemingly foreign to the main +argument, will concur to elucidate it; and all these rays of light will +converge to a common centre, reflecting, we flatter ourselves, some +evident facts and practical truths. + +This work on the contagious typhus of the ox is divided into four +principal parts. + +The first part contains the history of this typhus from the remotest +times down to the present day. It is divided into several sections. + +The second part, which gives the description of the disease, is +subdivided into four chapters. + +The first chapter treats of general typhus, in order that a perfect +understanding may be arrived at as to the name and definition of the +particular distemper which affects the ox. + +The second relates to the causes and origin of the disease. + +The third treats of its symptoms, its progress, &c. + +The fourth contains its mode of treatment. + +The third part gives some plain instructions for the benefit of farmers, +cattle-dealers, and dairymen. + +The fourth part gives a development of the scientific means and +safeguards to be adopted, in order that this country shall never relapse +into that state of helpless panic to which a want of preparation exposed +it when the present epizootia began its ravages. + + + + +FIRST PART. + + _The History of the Contagious Typhus of the Ox, from the + remotest times down to the present day._ + + +I. + +General, local, and particular causes of destruction are constantly +reacting on organized creatures, and these causes account for those +_epiphytic_ diseases which infest plants, the _epizootic_ diseases which +spread mortality among the brute creation, and the _epidemic_, which +strike and are fatal to the human species. Thus it is that we +particularize at present, in the vegetable kingdom, the disease which +has attacked the vines, olive-trees, and potatoes; in the animal +kingdom, the silkworm sickness, and the cholera, and the typhoid fever +of cattle: so that we may safely say, that one or other of these +diseases is always, at a given moment, raging in some part of the globe +among some species of animal, either birds, pigs, horses, sheep, horned +cattle, or, in fine, attacks man himself. + +When, however, the peccant invasion falls only on the vegetables and +animals situated at our antipodes, we seldom hear of the ravages it +commits; and when we do, forgetful of the affinity which links together +all the organic beings on the earth and their mutual dependence, nothing +can exceed the indifference we show to these calamities. Then, when the +danger threatens us nearer home, or when the evil has invaded us, we +have recourse to quarantine as the grand preservative to shield us. But +this preservative remedy is most frequently deceptive--a mere illusion; +for the real plague, typhus and cholera, borne along by the winds of +heaven, pass over the longest distances and the highest obstacles, and +baffle all our calculations; teaching us, by their successive returns, +that we shall continually be exposed to their destructive havoc so long +as we neglect to eradicate the evil at its original source, that is, in +those countries from which it emanates. + +And this is the place to observe, that the cholera morbus threatens to +keep a permanent footing in the English possessions of India, because +the public works, by means of which the great rivers used to be confined +to their beds, have not of late been repaired and kept in good order in +those countries; owing to which neglect, their waters overflow the +plains, leaving, when they subside, those pestilential deposits which +afford a perpetual incubation to the cholera. + +We are induced to dwell thus on the general causes of these diseases, +because the sick plants, on which dumb animals feed, and the sick +animals, on which man himself feeds, have a continual relation of cause +and effect; and we shall have to refer to this subject and give it +weight, when we come to speak of the treatment of these diseases. + +It is an important fact, which deserves our most pointed attention and +consideration, that the vital resistance inherent in the animal frame to +withstand the attacks of these contagious diseases, is very far from +being the same throughout the whole kind. Man, in this respect, is the +most favoured and best fortified; he is able, without much +degenerating, to inhabit any latitude, to go with a sort of impunity, if +his calling require him to do so, amidst the most pestilential +emanations, and to continue for hours inhaling their baneful fumes. We +could quote many striking examples of this resisting power in man. But +there is one which we have recently witnessed, and which all can +appreciate. We refer to the slaughter-house of the great Metropolitan +Market. Here we saw, in lumps and fragments, every variety of corrupt +_detritus_ of animals which had been seized with the contagious typhus; +we saw the animals, too, being felled and slaughtered and dissected, in +a high temperature which rendered the air so poisonous that we could +hardly breathe it; yet amidst all this infection the workmen employed to +move and handle these revolting wrecks appeared indifferent to the +scene, and quite in their usual health. No living animal besides man +could stand such a trial; no other could breathe for hours, and day +after day, like these workmen, an atmosphere so charged with decomposing +impurities. + +We say, therefore, that man may expose himself, with less danger to his +life than any other animal, to those pernicious causes which produce and +develop contagious diseases. Next to him, with respect to this power of +vital resistance, come the omnivorous animals, then the carnivorous, and +last of all, the herbivorous, in which this faculty is very feeble +indeed. + +This prime consideration, to be fully understood and appreciated by +unscientific readers, would require explanations beyond the scope of +this work. Let us, however, for the present establish the fact, that +herbivorous animals, such as sheep and horned cattle, offer but a very +weak resistance to the causes which generate infectious and epizootic +diseases, and let us do our best to prove it by demonstration; for if +this truth be once admitted, we shall therefrom deduce that it is the +duty of man constantly to surround these frail and delicate creatures +with special care and attention, if he wishes to prevent their being +decimated from time to time, and if he would likewise avoid the +consequent injuries to himself--the loss of health and money accruing +from this deterioration. + +So long as the herbivorous or grass-eating animal is properly fed; so +long as he browses on fat pastures; so long as his blood retains those +physiological elements which are the prime condition of health, he can, +and does, resist the causes of most contagious maladies. But if a hot +summer and a long continuance of dry weather chance to curtail, in +temperate zones, the usual abundance of his fodder, then comes the fatal +change: the blood is impoverished, the secretions are debilitated, a +strange languor runs through the system, the vital resistance is +unnerved, and he becomes an easy prey to those noxious influences which +were encountered before without injury whilst his provision was +abundant. + +This is a fundamental matter. We therefore beg leave to support and +justify our argument by borrowing some additional evidence from prior +labours of ours, accomplished at the Ecole d'Alfort, near Paris, +conjointly with Professor Delafond, whose name has so often been cited +in the public journals in connexion with the cattle plague. + +All vegetables and animals; with the exception of _adult_ men, whenever +their health declines from any cause (but more particularly from +paucity of food), spontaneously generate microscopic parasites, or very +minute insects, the germs of which are inherent in their system. A flock +of fleecy animals, wasted by deficient food in dry and parched meadows, +becomes attacked in due time by a parasitical cutaneous disease, known +as the _itch_, which is enough, if not checked, to destroy the whole. +Now, all that is required is to remove this flock to a more fertile +soil, where there is plenty to feed them, and the disease will disappear +of itself without any treatment. Deficiency of food destroys the health +of animals, and abundance of food overcomes disease in them. + +A sheep affected by this parasitical disease may, without any fear, be +placed in a flock of healthy sheep, for he will not propagate the +distemper; but if instead of being sound and healthy, the flock is in a +weak declining state, this contaminated animal will diffuse the disease +with frightful rapidity, and may cause their entire destruction. These +facts may seem startling, but we are only speaking after the +incontestable authority of experiments. + +We selected six healthy sheep, which we kept well supplied with +provisions; we covered these healthy sheep with parasites (acari). On +every one of these sound, well-fed sheep, the microscopic animalculæ +died off without generating the cutaneous disease; for the blood, the +humours, and the skin of sound and healthy sheep constitute a soil +unfavourable to the propagation of these parasites, and actually starve +them to death. + +After this first experiment, we subjected these six sheep to a deficient +diet; they grew lean, their blood was impoverished, and then all we had +to do was to lay upon them not thousands and thousands of these +parasites--as we had done in the first instance--but one solitary female +in a state of fecundity; and the parasitical distemper unfolded itself +so fiercely as to cause the death of three of these sheep on which the +test was allowed to run its course; whilst the other three sheep, having +been restored in time to a recoverable condition just as they were about +to drop off, were thoroughly cured, without any special treatment, by +the sole influence of good food and ordinary hygienic attention. + +Other tests, similar to these experiments, were applied to dogs, horses, +and horned cattle. A lean and scraggy dog, covered with parasites and +eruptions, with eyes running foul humour, a dog which could neither run +nor stand, and which was reduced to the last stage of wasting marasmus, +was rescued from the jaws of death and thoroughly cured without special +treatment, by the sole influence of a rich restorative diet. This dog +afterwards became a fine hunting hound, beautiful in shape, and +admirable for his sportive attributes. + +These experiments having been submitted to the judgment of the Académie +des Sciences in Paris, were honoured with its approval, and the reports +concerning them were printed at the Academy's expense, and crowned at +the competitive examination. + +The vital resistance of horned cattle is so feeble, that those animals +which are periodically exhibited in the north of London, though +certainly chosen from among the most healthy and robust, could not herd +together in large numbers for the space of a month in the Agricultural +Hall at Islington, without sinking under infectious and contagious +diseases--almost one and all. Under the conditions in which we see them +in that Show, a single month would be sufficient to produce almost their +complete destruction; for even a single week, which is the usual +duration of their confinement, affects them so much as to render a large +proportion of them unhealthy. + +Every one knows how apt cavalry horses are to sicken and die off during +a campaign. Every one has heard of the fearful ravages amongst the +horses of the Allied armies during the Crimean war, when many companies +were dismounted owing to this mortality. + +Let us now transport ourselves in thought into the middle of those +immense steppes where vast and innumerable herds of herbivorous animals +are being bred for our supply, and consider what will be the effects on +their health and life if they should be afflicted with a scarcity of +forage, in consequence of this long dry summer. + +It is unnecessary to say that there exist in Russia, in Hungary, in +Australia, in North and South America, and in many other parts of the +globe, large tracts of country which are still uninhabited, whose +uncultivated soil supplies with food great numbers of sheep and cattle. +These spacious tracts, known as moorlands or steppes, particularly +abound in Russia, on the banks of the Wolga, the Don, the Dnieper; in +Hungary, on the banks of the Danube; and also in South America, in the +republics of Venezuela, New Granada, Columbia, &c. + +Now, in hot and rainy seasons these steppes teem with rich and luxuriant +verdure; the plants growing up in the marshes are prolific and abundant, +and even those parts of the wild moors which produce nothing but heath +are capable of feeding and fattening flocks and herds. + +Under conditions so auspicious as these, animals may still suffer, but +in what way? By excess of food, or repletion. They are in general robust +and healthy, and thus fortified they inhale without detriment the +deleterious gases of oxygen with carbon, carburetted hydrogen and the +like, exhaled by the plants which grow out of the swampy soils. Thus +protected, too, they are proof against the fluctuations of the seasons, +and against every injury which threatens them; and their strong and +sound condition enables them to sustain the fatigues of their long and +arduous journeys, and to supply the rich countries of the West with +their flesh, fleece, and hides. + +When the seasons have thus conveyed a due proportion of heat, water, and +electricity to the elements of the soil, both plants and animals conduce +to the comfort and health of man, and fulfil his expectations. But the +laws of nature are involved in mystery. Good and evil go hand in +hand--death and life travel close together--and a few years of +prosperous harvests are almost invariably followed by blight, +barrenness, and scarcity. Most men think only of the present time, and +this imprudence and want of foresight prevent farmers and great cattle +proprietors from collecting and holding in reserve the requisite stores +of sustenance to supply their sheep and oxen during these barren +seasons. Sickness then breaks out, and these helpless creatures perish +in vast numbers, to the detriment of their owners' best interests. + +And truly, when continual rains cause the rivers to overflow, when the +plains are drenched and soaked, or when a burning sun scorches the +ground, herbivorous animals wander in vain from field to field in quest +of sustenance to restore their strength, or of pure and healthy water to +slake their thirst; their vital resistance dwindles away, deleterious +gases poison and bewilder them, their blood is debased, and as Ovid +says, + + "Corpora foeda jacent, vitiantur odoribus herbæ." + +And since these mild and harmless animals, which seem to have been +created merely to clothe us, and to nourish us with their milk and +flesh, have not been endowed by nature either with the intelligence, or +the activity, or the cunning, or the invention, or the skill bestowed on +the omnivorous and carnivorous species, hard is their fate under the +pressing needs of hunger. Peaceful creatures, they browse in vain on +deleterious plants on a sterile soil; their external and internal +teguments now afford a favourable seat for the propagation of +parasites--for the _parasitogenia_; and soon after a general _adynamia_, +or relaxation of the fibres, delivers them up without resistance to the +morbific elements of the infectious diseases to which they are exposed, +where the languishing, the sick, and the rotting are herded together, +and they are carried off by hecatombs by this wasteful and devouring +typhus. + + +II. + +We may readily conclude, from these general observations on infectious +and contagious diseases, that they must have existed in all former ages; +and if in our present advanced state of civilization they are so +destructive, we may be sure that in those remote periods they must have +been, both as regards man as well as the brute creation, the cause of +general extermination, in whatever parts of the earth they prevailed. +And indeed, whenever we refer to ancient or modern history, we are +continually struck with the analogy which exists between the epidemic +diseases signalized by the general name of PLAGUE, and which +decimated all the living beings, and those which more recently, and at +the present moment, have startled the world by their fatal effects on +men and animals. + +Moreover, we cannot too often repeat the fact--in order that those +documents relating to the past which contain useful instruction may be +examined and searched into--that the physiological and pathological laws +which rule and determine the phenomena of organic matter, whether in +health or sickness, were, like the laws of chemistry, electricity, and +astronomy, originally established at the time of creation, and that +matter submits with passive obedience to the laws of transformation and +transubstantiation, which are the absolute condition of life. These are +the eternal laws of which a synthesis so admirable is furnished by the +Gospel, in this short injunction, "_Take, eat, this is my body; drink, +this is my blood._" + +Now, if man, who is the sovereign master of this matter, did not take +care to regulate and modify it for his own benefit and the benefit of +all living creatures on whom his own life depends, as well as his wealth +and happiness; if he did not seek thereby continually to diminish the +sum of evil, and to extend the sum of good which it is his mission to +increase, he would violate these laws, which are inherent in matter, and +which have existed for his use since the creation of the world. + +We must likewise believe that those PLAGUES which are spoken of +in the Bible, those which Homer alludes to, that which is related by +Plutarch, and which succeeded the general drought in 753 before Christ; +those mentioned by Titus Livius, Virgil, Ovid, and other Latin authors, +the most virulent of which plagues raged in the years 310, 212, and 178 +of the Foundation of Rome, resembled the epidemics or plagues which are +witnessed in our own day. + +The plague of 212 swept away all the inhabitants of Sicily, cattle as +well as men; that of 178 destroyed all the priests, who sought in vain +for victims free from the contagion, to offer them up as sacrifices to +the offended Gods. + +Cecilius Severus gives a most striking description of a pestilential +disease which, in 376 A.D., swept away all the cattle in +Europe. Judging from his account of that scourge, we may fairly believe +that the distemper he has described was identically the same as the one +which has just broken out in England. "A universal distaste, sudden +dejection, vertigoes, spasmodic tension in the limbs, _a painful_ +_swelling of the lower belly_, violent affections of the nerves, sudden +death--everything shows the presence of a pestilential ferment, which +irritates the solids, infects and vitiates the fluids, which is the +cause of the putrefaction of the humours, manifested by the swelling of +the lower belly, which in that case depends on a putrid fermentation so +as to disengage air." + +A piece of iron, representing the sign of the Cross, was heated in the +fire, and when red-hot was applied to the forehead of the sick animals; +and this remedy was looked upon at that time as the most effectual they +could apply. + +Grégoire de Tours makes mention of an epidemic, the result of a long dry +summer, which, in 592, was very fatal in its havoc, sparing no living +creature whatever. + +André Duchesne, in his "History of England," speaks of an epidemic +which, in 1316, during the reign of Edward II., owed its origin, on the +contrary, to a long season of rains. + +The celebrated physicians Ramazzini and Lancisi relate that in 1711, an +ox which had been imported from Hungary, that constant focus of typhus, +displayed the most deadly form of the cattle disease, in the Venetian +territory, although no alteration in the air or waters had been observed +in Italy, and the seasons had been regular and the pastures abundant. +The contagion spread into Piedmont, where it carried of 70,000 head of +cattle; thence it extended to France and Holland, each of which +countries lost 200,000 of these animals. The trade in hides introduced +the distemper into England, where it proved no less fatal. It was the +same in the other countries of Europe. + +In this disease, the intestines of the affected cattle were, as in the +present epizootia, inflamed, and strewed over with livid spots and +ulcerations, and the blood, though apparently fluid in the body of the +animal, _coagulated directly after it had issued from the vein_. + +Herment thence concludes, that this epizootia is nothing more than an +inflammation of the blood. Lancisi advised his contemporaries to put to +death without pity every animal which was affected or seemed to be +affected with the disease; and it was in England that this spirited +resolve was first acted upon. + +The three counties of Middlesex, Essex, and Surrey arrested the course +of this contagion in less than three months, by adopting this measure; +whilst in the rest of the stricken counties of Great Britain, and +likewise in Holland, where this decisive course was not taken at all, +the disease prevailed among the cattle for several years. Since that +time, it has been insisted on by some authors, that the barbarous +process of general extermination offers the most effectual remedy which, +in our present state of ignorance and improvidence, we could have +recourse to, in order to check the diffusion and the duration of this +fell disease. + +The learned Goelicke describes an epizootia which was witnessed in 1730, +at Frankfort-on-the-Oder. His narrative, written with a masterly hand, +might very properly be applied to the disease which we are now +considering; and the treatment recommended by this earnest and vigilant +observer is so wisely deduced from the symptoms, that even in the +present day we might take that treatment as a model. + +We could have borrowed much more largely from this source of +biographical researches had we not deemed that these quotations would be +sufficient for the purpose we had in view in this work. But from these +authorities we think it may justly be concluded, that infectious and +contagious diseases among horned cattle have frequently appeared from +the remotest times down to the middle of the eighteenth century. + +All these attacks of epizootia were a frequent and severe cause of +suffering and misery among animals and men; but the ravages which they +left behind them were of slight importance each time, if we compare them +with those attending the epizootia which towards the year 1746 affected +the animal kingdom. This dreadful scourge lasted ten years, and swept +away nearly the whole race of horned cattle throughout Europe. It was +closely studied and thoroughly understood in its causes, its symptoms, +and its treatment by the scientific authors of that day, and those +writers, more judicious than we, did not designate the malady by the +title of PLAGUE. This particular visitation deserves to fix our +attention in an especial manner, not only on account of its striking +resemblance to the disease which now makes us all so anxious, but +because it induced two English physicians, Malcolm Flemming and Peter +Layard, to write on this disease two accounts or statements which are +equal, if not superior, to all the volumes which have since appeared on +the subject of the Cattle Disease. There is no help for it, and our +pride must bend itself to the acknowledgment: these two men, our seniors +by a century, were men of quite another stamp. Their expositions, +enriched with quotations from the Greek and Latin authors, abounding in +facts, ingenious insights and inferences, are far superior in merit to +the multitude of voluminous works which have been written and published +since then. It would be easy to prove that these two sagacious inquirers +far better understood than we have done the real nature of this cattle +disease, and that we must be grateful to them for first opening the way +which all of us must take in order to discover the preventive and +curative means of which we are still ignorant. + +Let us observe, in passing, that these two physicians, who appear to +have been scarcely known, enlightened by the effects of the inoculation +of small-pox, then practised from man to man, appear to have first +conceived the idea, now practised in Russia, of preventing the +propagation of the contagious cattle disease by means of inoculation; +and we may raise the interest of this remark by reminding the reader +that their experiments to inoculate cattle were made in 1757, eight +years after the very year which gave birth to the future inoculation of +man with animal virus by the celebrated Jenner. By this it would appear +that the twofold honour of applying the method of inoculation as both +preventive and curative means in respect of contagion in cattle, and as +the preventive means by the variola of the cow to resist the ravages of +the small-pox in man, is the indisputable claim of English +physicians.[A] + + +III. + +Very little is known of the origin or first outbreak of the epizootia +which produced such fearful ravages in the middle of the eighteenth +century. Some suppose that it first appeared in Tartary, where it +occasioned a disorder twice as extensive in its pernicious effects as +any similar distemper which had been known up to that time. Thence it +passed into Russia, from which it spread on one side into Poland, +Livonia, Prussia, Pomerania, and Holland, and from that country into +England; on the other side towards the East, it invaded the Turkish +Empire, Bohemia, Hungary, Dalmatia, Austria, Moravia, Styria, the Gulf +of Venice, Italy, Spain, Portugal, France, the banks of the Rhine, and +Denmark. + +But another opinion has assigned Bohemia as the source from which this +destructive epizootia took its rise, and its supporters allege that +during the siege of Prague the cattle feeding in its plains had been +deprived of their usual fodder by the continual _razzias_ of the French +to supply their own cavalry. + +Be this as it may, this virulent cattle disease having at length +assumed the proportions of a public calamity, the several governments +were obliged to take it into serious consideration, and the medical +faculties and most celebrated physicians began to make it the subject of +their studies and reports. In France, therefore, the professors of the +faculty of Paris and Montpellier, suspending every other pursuit, +devoted their most assiduous care and attention to dumb animals. + +Sauvages, the Dean of the Faculty at Montpellier, drew up a most +philosophical and learned account of the prevailing disease, in which, +like Stahl, he forgot probably for a moment the part which, in the +progress of distempers, he ascribes to the soul. + +The professors of Paris, very famous in their day, but who, having left +behind them no works so valuable as the "Nosologia" of Sauvages, are now +completely forgotten, likewise addressed the result of their inquiries +and lucubrations to the King. + +Doctor Leclerc was sent into Holland, whence he brought back a Memorial, +which was a reflex of the opinions he found current in Denmark, and +which has been transmitted to us in the _Memorials of the Royal Society +of Science at Copenhagen_. + +It is evident from the reflections found in the writings of Malcolm +Flemming, Layard, and other competent observers, that this formidable +epizootia was in its character identical with the one described by +Ramazzini and Lancisi in 1711; and we feel warranted in saying, after +having examined every work of any importance which has treated of that +visitation, that it resembles the disease now prevailing among cattle, +in its march, in its symptoms, and in its gravity. We believe that these +three visitations constitute but one and the same malady, occurring at +three different periods. This appears to us a most important fact, for +if such be the case, the tentative treatment of that time deserves our +most particular attention. Consequently, a few retrospective glances may +perhaps be permitted us, in considering the subject of cattle disease. + +The medical professors (including several English physicians), who +observed and described the epizootia of 1745, divided the same into +three periods. + +The duration of the disease, when it passed through all its phases up to +the death of the affected animal, consisting of from ten to twelve days, +they usually ascribed to each of these periods or stages an average +continuance of three or four days. + +_1st Period._--After a few days of latent incubation, which the observer +could not suspect, the sick animal betrayed signs of the morbid state +which was about to declare itself, by his careless feeding, by drooping +his head, and by exhibiting the deepest dejection of spirits in his +attitude and look. Rumination, already imperfect, soon ceased +altogether, the appetite failed, the horns, ears, and hoofs were cold, +the hair grew stiff, the tongue and mucus looked white; the eyes were +tearful and fixed, the hearing obtuse, whilst, in the cows, the supply +of milk diminished. In cases of unusual gravity, transient shiverings +testified to a serious disturbance in all the animal functions. These +shiverings were followed by a violent fever, the blood became inflamed, +the breath hot, the respiration hurried and sometimes attended with +slight coughing; when, if too violent a repercussion was transmitted to +the nervous centres, the pressure on the vertebral line became +intolerable, and the animal, seized with vertigo, and almost delirious +with pain, would fall during this first period, as if struck by +lightning. + +The same phenomena are sometimes observed in the typhoid fever of man, +which offers moreover some analogy with the contagious typhus of the ox; +but as the ox and the horse have likewise the real typhus fever, they +may some day supply us with the preventive virus for that fever, in the +same manner as the cow now supplies us with the preventive virus for the +small-pox. + +_2nd Period._--In most cases the disease pursued its course with greater +or less regularity; the sick animal experienced gnawing pains or +twitchings, and spasmodic shootings in the limbs, apparently attended +with pain. His thirst was insatiable, but he had no appetite, the +functions of the bladder and intestines were impeded, then diarrhoea +supervened, accompanied with dry, fetid, and sometimes bloody excreta. +Thick viscid mucosities dripped from the nostrils, mouth, and eyes. The +dorsal regions and the loins were constantly aching, headache and +sleeplessness were permanent. The animal continued either standing or +lying down, and if he wanted to rest, he could not bend himself +gradually, but would fall like an inert mass to the ground. + +_3rd Period._--Diarrhoea was continual, becoming more fetid every day, +the wasting of flesh made rapid strides; the cellular tissue beneath the +hide was filled with gas along the vertebral channels and under the +abdomen; the nostrils were stopped up with mucosities, the animal could +only breathe through the mouth, puffing and blowing aloud as he drew in +the air; and at last pustular eruptions showed themselves on various +parts; but as this depurating crisis was insufficient, the poor beast, +in this final period of the attack, fell a sacrifice to it between the +seventh and twelfth day. If he chanced to be lying down his agony was +slow, but if standing, he would sink upon himself, and expire at once. + +In this dreadful epizootia, very few of the smitten cattle survived--not +more than four or five in a hundred; and in these favourable cases, the +symptoms presented certain signs and critical phenomena of a happy omen. +In these rare exceptions, the pulse did not exceed seventy, the +beatings of the heart were always perceptible, the patient did not +refuse to drink, the continuous fever exhibited no aggravation at night, +pustular eruptions and tumours appeared on the dewlap and the fore +limbs, and the epidermis over the mouth and nostrils peeled off about +the twelfth day. + +When dissected, the bodies offered to view the following alterations, +the same having already been observed by Frascator during the prevalence +of the epizootia in 1514, and by Lancisi and Ramazzini during that which +was so fatal in 1711. The mucous glands of the mouth were livid, and +occasionally excoriated; the bronchial tubes were obstructed with +mucosities; the lungs, besides being partially congested, were sometimes +emphysematous, that is, inflated with compressed air. Of the four +stomachs, the rumen was full of food, the reticulum, the omasum, and the +abomasum exhibited purple or livid spots, according to their place. The +thin intestine and the thick intestine showed either a general +injection, scattered livid spots, or ulcerations, according as the fever +had worn the exanthematous or typhoid form; for the mucous membrane of +the digestive channels, and especially that of the intestines, displays, +like the external tegument in man and the brute creation, divers forms +of inflammation, analogous with the measles, the scarlatina, and the +small-pox; so that, if the typhoid fever in man, which is nothing else +than the small-pox of the intestines, is so frequently cured, it is +because the general morbid condition, the fever, often conceals +different intestinal lesions, albeit they seem to be similar in the +general symptoms, which taken collectively constitute the disease. + +The flesh of these diseased animals was blackish, and devoid of blood; +the animals which fed upon it, if uncooked, sickened afterwards, or +died. The wrecks of the bodies, and more particularly the skin, +sometimes retained a strength of contagion so deadly, that the mere +exportation of them was enough to cause its propagation, and to this +cause was at that time attributed the outbreak of the contagion in +England. + +An extraordinary case of this pernicious influence, which is related by +Hartmann, who observed this epizootia at its decline in 1756, will give +an idea of the subtlety of this malignant virus. + +A farmer who had lost an ox in consequence of that virulent distemper, +buried it in one of his fields. The following night a bear smelt the ox, +raked it up with his feet, ate a portion of the flesh, and a few days +after, the beast of prey was found dead in a neighbouring wood by a +peasant in the parish of Eumaki. The skin belonging to this bear was +magnificent. The peasant flayed the animal and carried home his skin in +triumph. But his triumph was short; for that same night the poor +countryman fell ill, and died two days after the attack. The magistrates +of Wiburg, having heard of this occurrence, sent orders to have the +infected skin burned. Meanwhile, the skin had been given to the curate +of the place as a compensation for the offices of burial; but his +cupidity having persuaded him that this fine skin could not have +destroyed the peasant whom he had just buried, he did not burn it at +all, but induced another peasant to clean and dress it for him. This +simple fellow and two other clodpoles, who assisted him in the +preparation, fell ill, and all three of them died in the course of a +few days. A new and peremptory order now came from Wiburg to burn this +skin, to burn the house in which it had been dressed, to burn even the +presbytery itself, should it be deemed necessary. The skin had already +passed through several hands. However, the curate being still reluctant +to part with it, took it home again. "Can it be possible," said he to +himself, "that this skin has really proved fatal to life? What can have +been the cause, I wonder?" At the same time he rubbed it in his hands +and smelt it. Unlucky curate! A few days afterwards he himself was taken +ill and died. (_Memoirs of the Academy of Stockholm._) + +A native of Clermont Ferrand, in the department of Puy de Dôme, in +France, the birth-place of Pascal, one day finding an ox which had died +of the epizootia, stripped off the skin and carried it away. After his +return home, the black typhus, and then gangrene, broke out on one of +his arms, which had to be cut off, and the patient died of the effects +of the amputation. + +A butcher having slaughtered an ox smitten with this typhus, sold the +flesh for meat to some soldiers of the Regiment Royal Bavière, then +garrisoned in one of the towns of Languedoc. All those who partook of +this meat were seized with diarrhoea, dysentery, and fever, and +several of the sick soldiers very nearly died. The butcher, whose +avarice had caused all this mischief, had richly deserved some exemplary +punishment, and some of the sufferers proposed that he should be hanged +outright, but the majority, more clement, sentenced him to be beaten +black and blue with horsewhips. + +The popular saying, _when the beast is dead the poison is dead_, being +generally true, the virulence of the contagion, in the above instances, +possessed venomous properties of an exceptional character, for if every +sick animal slaughtered by the butchers and sold to the consumers, or +those which had been flayed for the sake of the skin, had contained so +murderous a virus in their tissues, the number of victims to the +contagion among the human species would have been appalling. And in that +case, too, similar sacrifices would be witnessed at present, for it +cannot be doubted that, in the actual state of the meat market in +London, the people are now in the daily habit of eating the flesh of +cattle which are diseased. + + +IV. + +Physicians of different countries have naturally bestowed much time and +care in considering and discussing the nature of this epizootia, because +they have felt that a satisfactory theory and appreciation of its +principal phenomena, might afford the medical faculty a rational basis +for some special treatment. + +Layard and the physicians of Geneva have considered this cattle disease +to be _a malignant fever with an eruptive tendency_. + +In the estimation of the faculties of Paris and Montpellier, this cattle +disease, considered in its symptoms, was nothing more than _a malignant +fever essentially contagious_, the action of which appeared to tend +exclusively towards the skin, and therefore it was rational to provoke +external eruptions and deposits which, as they matured, diverted from +the centre the greatest part of the morbific matter. + +_The treatment_, to which, above all, we invite the reader's attention +(more particularly that of medical men), necessarily varied according to +the period of the disease. It was sometimes preservative, sometimes +curative, as the case might be. + +_The Preventive Treatment._--The farmers and cattle-breeders, whose +herds were still exempt from the contagion, mindful of the advice which +they received through the public press, took very particular care of +their cattle during this season of epizootia: they rubbed them over with +a brush, and washed them at least once a day; they sheltered them from +the inclemency of wind and rain; they took their milch cows, which until +then they had kept shut up in unhealthy cow-houses, into the open air of +the fields; they washed and fumigated the stables; they examined the +quality of the fodder and of the other articles of food; they added +marine salt to their drinking water, or poured salt water over their +forage; and above all, they took care that no foreign animal commingled +with their flocks and herds. + +Some physicians, on their side conscious of the duty which devolves upon +them in such seasons of calamity, instead of resting satisfied with +recommending remedies, betook themselves boldly to the work, and studied +the disease experimentally in respect to its propagation and prevention. + +Thus, for instance, certain Dutch physicians, in 1754, wishing to know +whether the morbid matter would transmit the disease by inoculation, +made incisions in the necks of some oxen, cows and calves, inserting in +the wound a little tow saturated with the morbid secretions discharged +from the eyes and nostrils. This direct inoculation having been +practised on seventeen animals, transmitted the disease to them all in +the course of a few days. + +The English physicians having been made acquainted with these +experiments, applied them to a more practical purpose, no longer to +discover whether the disease could thus be transmitted (for that had +been proved), but to find out (what was far more important) whether this +fearful distemper could be prevented and kept off. + +Malcolm Flemming, in 1755, merely suggested the idea of inoculation as a +preventive means, without proceeding to a course of experiments to +ratify his opinion. He intimates his notion in the following terms:-- + +"I apprehend that inoculation will stand the better chance of bringing +on the distemper, if the subject it is performed on is as young as +safety will permit, the vessels being then most absorbent, and the +animal economy most easily put into disorder. + +"But even in case the inoculation of calves should be found so +successful as universally to prevail, the method I recommend will not be +altogether useless; for, by being properly modelled and adapted to +circumstances, it may, I am persuaded, prevent contagion, and likewise +act as a preparative in any epidemical affection of the inflammatory +kind, not only in horned cattle, but likewise in all other quadrupeds +that civil society may think worthy of preservation, and even in the +human species." + +Layard, in 1757, devotes the seventh chapter of his work, "The Means to +prevent the Infection," to the consideration of the preventive +treatment, in which he says:-- + +"No one will think of bringing the infection into any place free from +it, merely for the sake of inoculating their cattle; but if the +contagious distemper be in the neighbourhood of a herd, or break out so +as to endanger the stock, the grazier or farmer may, by inoculating his +cattle, with proper precautions, at least secure his stock, since he can +house them before they fall sick, prepare them, and have due care taken, +knowing the course of the distemper. + +"Sir William St. Quintin, the Rev. Dr. Fountayne, Dean of York, and +other gentlemen have succeeded in inoculation: in Holland it has both +failed and succeeded. These gentlemen all inoculated with matter taken +from the running of the mouth, nose, or eyes. Professor Swenke mentions +that the beast from which he took the matter was recovering from the +distemper. A circumstance to be attended to is this:--had matter been +taken after the crisis, from a tumour, boil, pimple, or scab, either on +the back near the spine, or on the legs, the pus would have proved much +more elaborated, subtle, and infecting than that which, flowing with the +mucus of the nose, must necessarily be, in some degree, sheathed by this +glutinous excretion, though I am well aware how putrid and acrid it is +rendered by the disease. + +"That nothing may be omitted which in any shape can contribute to the +success of inoculation, due attention should be paid to the constitution +and state of the beast, no less in this practice on the cattle than on +the human species. Undoubtedly the young, healthy, and strong bid fairer +for a good issue than the old, sickly, and feeble; each of these +different constitutions demand a particular treatment, even in the +method of preparation; and however trifling it may seem to many--the +urging a necessity of preparation--I will venture to affirm that I have +seen excellent effects arising from a rational preparation, and fatal +events from want of preparation. I have likewise been witness of +unfavourable turns, merely from an injudicious preparation. + +"The beasts which are sanguine require moderate bleeding; those that +have but a small share of blood must have none drawn. The strong must, +besides moderate bleeding and purging, be kept on light diet, and their +body kept open. Thus, scalded bran, mixed with their hay and chaff, will +cool them. The weakly, and such as are inclined to scour, must be kept +on dry fodder, and have peas and beans given them to strengthen them. A +mess of malt, or a quart of warm ale, with a few spices, will be very +suitable for them. + +"Whatever diseases the cattle may be affected with, if time will permit, +they are first to be removed. + +"The cattle to be inoculated are first to be well washed, rubbed dry, +and then curried, to remove all the filth from the hair and skin. Then +they are to be placed in a spacious barn or stable, where the air is +temperate and no cold can come to them. There they are to be prepared +according to the direction already given, foddered with good sweet hay, +and watered with clear spring water; and if the distemper be not near, +they may be turned out into the air, near the barn or stable, and may +stay there a few hours in the middle of the day. + +"When it appears that the cattle are in perfect health, free from any +infection or disease, brisk and lively, neither costive nor scouring, +and chewing their cud, then the operation may be safely undertaken, and +henceforth they must be confined to the barn. + +"Since there is observed to follow the greatest flow of the contagious +and putrid particles separated from the blood, wherever the infectious +matter makes an impression at first, particular care must be taken not +to inoculate near such vital parts as the heart and lungs, nor near the +womb, if a cow with calf be inoculated; for, though rowels are properly +applied in the dewlaps to draw off the pestilential humour from the +breast, and in other cases beasts are frequently rowelled in the +flanks,--yet, in this operation, as matter is inserted by these channels +into the neighbouring vessels, those vital parts, or the womb, might +become the chief seat of the disease, and the event prove fatal. + +"To prevent such accidents, human beings have been inoculated on the +arms and legs, and now-a-days the arms are found sufficient. I would +recommend that the cattle should be inoculated about the middle of the +shoulders or buttocks, on both sides, to have the benefit of two drains. +The skin is to be cut lengthways two inches, deep enough for the blood +to start, but not to bleed much. In this incision is to be put a dossil +or pledget of tow, dipped in the matter of a boil full ripe, opened in +the back of a young calf recovering from the distemper. It may not be +amiss to stitch up the wound, to keep the tow in, and let it remain +forty-eight hours. Then the stitches are to be cut, the tow taken out, +and the wound dressed with yellow basilicum ointment, or one made with +turpentine and yolk of egg, spread on pledgets of tow. These dressings +are to be continued during the whole illness, and till after the +recovery of the beast, to promote the discharge; and then the wound may +be healed with the cerate of lapis calaminaris, or any other. + +"On the third day after inoculation, the discolouring of the wound, +whose lips appear grey and swollen, will be a sign that the inoculation +has succeeded; but the beasts, as Professor Swenke informs us, did not +fall ill till the sixth day, which answers exactly to the observations +daily made in the inoculating of children. Yet the Professor adds that +on the third day a costiveness came on, which was removed by giving each +calf three ounces of Epsom salts. + +"No sooner do the symptoms of heaviness and stupidity appear than the +beasts must have a light covering thrown over them, and at night +fastened loosely. They must be rubbed morning and evening, and curried, +till the boils begin to rise; warm hay-water and vinegar-whey must be +given plentifully. Should the beasts require more nourishment, dry meat, +such as cut hay, with a little bran, may be offered. I should be very +cautious in giving milk-pottage, even after the boils and pimples had +all come out, for fear of bringing on a scouring. However, this caution +is proper, that whenever milk-pottage be given, the vinegar-whey is to +be omitted for obvious reasons. In cases of accident, the same attention +is to be observed in the disease by inoculation as in the natural way, +and the medicines recommended are the same I would use; but by +inoculation there seldom is a call for any, so favourably does the +distemper proceed through its several stages. + +"The crisis being over, it will be proper to purge the cattle, to air +them by degrees, and to have the same regard in the management of them +as is laid down in the chapter on the method of cure." + +Such are the recommendations which Layard has prescribed for those who +have to practise inoculation as a preventive treatment; it would be +difficult to offer an example of greater prudence or precision. + +A certain number of oxen were, by means of this inoculation, protected +against the attack of the cattle disease; and this mode of treatment +was, as we shall afterwards explain, adopted in Russia. Unfortunately, +this rational and preventive treatment was discovered only at the end of +the epizootia, when already upwards of six millions of horned cattle had +fallen a sacrifice to the contagious fever. + +_Curative Means._--When the first course of the disease had left no +doubt of the attack, the sick animal was subjected to an appropriate +diet, and restricted to liquids either as medicinal decoctions, or as +alimentary beverages. The decoctions consisted of whey mixed with a +little vinegar, and nitred hay. The broths, or alimentary beverages, +consisted of a decoction of bread, and of water mixed with bran and +meal, whether of barley, oats, or wheat. + +At this stage of the curative process, the majority of physicians +recommended one or two bleedings, in order to abate the violence of the +fever, and of the congestions near the nervous centres and the lungs; +and as constipation prevailed at the time, they strove with the same +object to empty the digestive passages, the intestines, and the +stomachs, notwithstanding the difficulty that exists to produce this +result in ruminating animals. + +The purgatives employed consisted of a decoction of senna, mixed with +prune juice, with a little rhubarb or fresh linseed oil, infused in +their drink, or applied as a clyster in warm water slightly salted. +Those who practised polypharmacy administered at night a mixture of +nitre, camphor, red-lead, and rhubarb, in half a pailful of warm water; +and greatly did they boast of the active influence of this beverage. + +Some practitioners even endeavoured, in the first stage of the malady, +to accelerate its action on the skin by giving for that purpose warm +drinks, and by covering the cattle with woollen cloths, to promote +perspiration; but it was generally admitted that the sick animals +preferred cold drinks, and that they were particularly fond of +acidulated whey. + +In the second period of the distemper, the same drinks were continued, +adding thereto some theriac or Jesuit's bark, in order to lessen the +frequency of the diarrhoetic evacuations. They also provoked the +depurating secretions from the mouth, nose, and eyes, by repeated +washings; and as those animals, in which the running was most easy and +copious, seemed to be less seriously affected with the disease, they +strove to increase that which flowed from the glands of the mouth by +fixing a gag in the jaws, and keeping it there for several hours. This +measure seemed so efficacious that a decree from the Parlement de Rouen, +issued on the 13th of March, 1745, ordered the application of a gag, or +bit, for three hours every day, to the cattle under treatment. + +In the third period, they sought to overcome the wasting of strength in +the system by means of tonic and nutritious drinks, decoctions of +centaury, Jesuit's bark, juniper berries, &c. They likewise administered +emollient clysters if the evacuations were bloody. + +Moreover, they placed two or three setons, principally in the dewlap, in +order to obey the signs and indications of nature--_quo natura vergit, +eo ducendum_; as a salutary and critical eruption of the skin was at +that period forcing its way. These setons were kept open with a mixture +of turpentine and yolks of egg, for the purpose of encouraging the +secretion. The purulent or emphysematous tumours were cut. + +But whatever means might be employed, almost all the cattle perished, +and the few and rare recoveries only afforded the pessimists the +satisfaction of claiming the merit of them for themselves. It was +remarked, besides, that the fattest beasts were the least able to resist +the effects of the distemper. + +It is hardly necessary to say, that during the whole course of the +treatment, great care was taken to keep both the stables and the cattle +in a perfect state of cleanliness. + +The convalescence of those animals which were cured was invariably long, +and required great attention as to their food and hygienic treatment. +Solid substances, roots, and forage were withheld until rumination +revived; and it was only after several days of encouraging trials that +the recovered animal was suffered at last to feed all day in the field, +according to his pleasure. + +Such, then, was that formidable epizootia which, in the middle of the +eighteenth century, swept away upwards of six millions of horned cattle, +and which occasioned a loss to Europe exceeding fifty millions +sterling--perhaps we might say a hundred millions--for other domestic +animals, sheep, horses, &c. (as generally happens in cases of +epizootia), had likewise suffered, in different degrees, from the +various complaints arising from inclement seasons. + +It was certainly necessary to our purpose that we should have taken this +retrospective view of the cattle disease, and it will afford us a +valuable guide for the future. We may now content ourselves with +bringing together the different annals in the chain of time which +elapsed between Layard's treatise, which was published in 1757, and the +present day. This chain of time amounts to 108 years. + + +V. + +The typhus of Horned Cattle, which had shown itself in a manner +permanent, sometimes raging at one part of the globe, sometimes at +another, could not, under the unaltered conditions by which it had been +generated, suspend its ravages; and though, thanks to her isolated +position, England may be less exposed to it than other countries, it is, +however, necessary to take note of what may serve for our instruction in +the several epizootics which will pass under our view. + +Medical writers relate that contagious typhus broke out several times in +Holland during the years 1768, 1769, and 1770; it also appeared in +French Flanders in 1771, in Hainault in 1773. In France one particular +spot was, at this period, completely rendered intact by drawing a +sanitary fence about its limits, and bestowing on the cattle particular +hygienic attention as a safeguard. The stables of these animals were +washed, cleansed, and fumigated; spring water was given them to drink, +their food was chosen with care, and a certain quantity of salt was +mixed with it. + +In 1774, Holland, a cold and damp country, was once more invaded by the +scourge; and the Government offered in vain a reward of 80,000 florins +to any one who should discover the preventive or specific remedy for the +disease. + +The typhus which, at that epoch, had likewise broken out again in the +south of France, threatened to become an abiding peril to the wealth of +nations. Two French authors, Vicq d'Azyr and Paulet, betook themselves +earnestly to the task of collecting every document which up to that time +had been published on the successive visitations of the malady, and of +offering the means of preventing it. Their intention was unquestionably +laudable, but the time for obtaining such a result had not yet arrived; +besides which, these two writers, whatever may have been their desert, +were not equal to an achievement of this character. They belonged, +indeed, to that order of men who look upon the cultivation of science +solely as a step to personal distinction. + +Vicq d'Azyr himself was but twenty-five years old when he issued, in +1775, his work, entitled, "Exposé des Moyens curatifs et preservatifs +qui peuvent être employés contre les Maladies des Bêtes à Cornes." We +should deceive ourselves if we expected to find in this exposition +anything but an interesting compilation of the works already published. + +Paulet's treatise appeared likewise in 1775, under the title, +"Recherches historiques et physiques sur les Maladies epizootiques, avec +les Moyens d'y rémédier dans tous les Cas, publiées _par ordre du Roi_." +Paris. Two volumes. + +After reading and reflecting on this title, as servile as it is +arrogant, I might have dispensed with all examination of the work. A +scientific man, whilst in the pursuit of truth, takes orders from +nobody, not even from kings. Paulet, therefore, writing _by order_, +could only produce a work of mediocrity, and such is incontestably the +degree of value of his two volumes, forming, as they do, a fastidious +dissertation of epizootics in general, and of those relating to cattle +in particular. + +The works of Paulet and Vicq d'Azyr, written at the same time, not being +the labour of men practising the medical art, are on a level as to the +notions which they have handed down to us; but that of Vicq d'Azyr +being the better of the two, we shall extract therefrom what may chiefly +interest us. + +Vicq d'Azyr relates the history of the epizootics, and expatiates on the +original cause of the typhus in horned cattle, and on its nature. The +passages in which he treats of its mode of propagation and its +treatment, are the most deserving of our notice. + +He says, that he tried to no purpose to communicate the disease a second +time to animals which had been fortunate enough to get cured. + +That cows covered with the fresh skins stripped from dead cattle, +victims to the distemper, did not contract it. + +That infected clothes which had been worn by men who had served in +hospitals where cattle were under treatment, having been laid on the +backs of several beasts in sound health, were found to transmit the +distemper in three cases out of six. + +That the gases expelled from the intestines, received into a bladder +ball, and let out under the noses of healthy cattle, have communicated +the disease to them, after ten or fifteen days of latent incubation; +and that the same gases being mixed with their drink, have also +propagated the contagion. + +That frictions, with the hands impregnated with virus, having been made +over the skin, did not produce any ill effects. + +That some oxen which had been designedly placed for a few hours among +sick animals, have afterwards been seized with the distemper. + +That a calf which had been placed in a stall containing some oxen +grievously affected, but which calf had a basket beneath its nose filled +with aromatic herbs, withstood the contagion. + +That cowsheds which had been partially cleansed and fumigated, +transmitted the disease to other cattle, even several months after they +had been vacated. + +Finally, he mentions the experiments of inoculation made by Lay and in +England, but not understanding their aim and capacity, he adds, that +inoculation does not seem to him of any use, since the inoculated +animals all died. Yet he quotes the encouraging results obtained by +Camper in Holland, who, out of 112 inoculated cattle, saved 41; and +those of Koopman, who, out of 94, cured 45 by this very inoculation. + +He reminds us that the cattle typhus is an abiding disease in Hungary +and Russia, where the beasts having bad water to drink, can only be +protected by a constant use of marine salt (_sel gemme_); but being +deprived of this salt, when they go great distances to be sold, and +being exposed to extreme fatigue and privations, the typhus then spreads +among them. He likewise tells us that Hungary and Dalmatia, which used +to supply the markets of Italy with butcher's meat, were obliged to give +up sending any cattle there, the Italians having firmly refused to +purchase the same at any price whatever. + +As regards treatment, the advice which Vicq d'Azyr gives to +agriculturists, is mostly borrowed from the authors who have written on +the great epizootics of 1711, and 1745 to 1755. Thus, he advises them to +give as drinks in the first stage, water whitened with meal and nitred; +to purge the animals with linseed oil; even to make scarifications on +the skin, and to keep up the suppuration with turpentine; to make the +animals inhale six times a day vapours seasoned with vinegar; to wrap +them over with woollen cloths; to bleed them once or twice; to +administer to them, when diarrhoea shows itself, a beverage containing +wormwood, quinine, and diascordium; to cut open the tumours containing +pus or air, etc. + +It is, as is seen, the same treatment as that quoted above; he +guarantees its success, and supports his views by the authority of Van +Swieten and Huxan. + +Van Swieten, however, had somewhat modified the treatment, by the +predominance which he allowed to acids; and this course seemed to him to +be only reasonable with respect to animals whose sick humours contain an +excess of alkali. + +Vicq d'Azyr fixed his attention on the means of prevention, the most +effectual of which, in his opinion, was to slaughter every animal which +had either sickened, or had been exposed to the influence of the +contagion; and as he insisted that the authorities had no measures to +keep in this matter of public interest, he made it a principle that the +government was bound to compensate the cattle proprietors whose animals +had to be killed--the more so, said he, that the crafty husbandmen would +never come forward and freely declare the invalidity of their cattle, +unless some indemnity were held out to them, which they would look upon +as a sort of equivalent for the benefits they had expected by cutting +them up and selling them as the food of man. + +The doctors of the period, scenting in Vicq d'Azyr a dangerous +competitor, considered the advice of exterminating the diseased cattle +as an _ingenious means of curing_ them, and as the author's age and +experience gave warrant for this satirical tone of discussion, the +public joined them in laughing at him. + +The epizootic typhus, if not so destructive, was at least as frequent in +the early part of the nineteenth century, as it had been during the +eighteenth. The armies during the wars of united Europe against the +French Republic and Empire, found it constantly in their train. Nor +could it be otherwise, the two leading causes of its prevalence being at +hand. For on one hand there was the transit of large herds from the +steppes of Hungary, and on the other the wretched hygienic conditions +amidst which the cattle had to live in the campaigning armies. + +Many books have been published of late years on the diseases of cattle, +in France and Germany; and several distinguished English veterinary +surgeons, especially Professor Simonds, have also devoted their +attention to the same subject. In the second part of this work, we shall +have occasion to refer to their labours. + +In France, Renault, Delafond, d'Arboval, Gellé, whose works enjoy a +deserved reputation, have discussed the subject of the origin of this +disease. + +Renault asserts that the disease has but one single focus, the steppes +of Russia and Hungary. The epizootics of Asia, Africa, and South America +are caused, he considers, by the importation of animals to those +countries. It is thus that he explains the epizootia which, under the +name of Delombodera, devastated the American Republics in 1832, and that +which, in 1841, appeared in Egypt. Renault thinks that neither the long +transit, nor the filthy state of the markets, nor the most wretched +feeding, are sufficient to account for contagious typhus among cattle; +that in addition to these causes, it still requires, in order to produce +and generate it among animals, a predisposition, and a special aptitude, +such as, hitherto at least, do not appear to have been witnessed except +in the progeny of the steppes. + +The other professors of his fraternity have submitted arguments to him, +which to us seem very rational; and we will endeavour to do justice to +them when we discuss the origin of the typhus which at this moment is +afflicting England. + + +VI. + +These historical dissertations and speculations on the subject of the +bovine epizootia certainly deserve to draw the attention of all who feel +an interest in the malady; but how insignificant they are compared with +the concluding facts which I have still to mention, before I at length +address myself to the consideration of the epizootia which is now +consuming our herds! + +The indisputable fact that so terrible a distemper as this typhus had +fixed itself permanently in Russia, and that it was causing incalculable +losses to the lordly proprietors of the steppes, as well as to the +government, roused them at last from their indifference. Then, indeed, +they urged the veterinary doctors to adopt some energetic means to +arrest the long duration of the scourge, and we must admit to their +honour, that various experiments which were tried for the purpose of +preventing the evil, have been crowned with complete success. Any one +may ascertain the fact by referring to the _Journal Magazin_ of Berlin, +in which the learned Professor Jessen of Dorpat has explained the +results of these important experiments. + +The Russian veterinarians having observed that the oxen which had been +cured of the typhus could mingle with impunity with the infected herds, +conceived the idea of communicating the complaint to sound cattle by +means of inoculation, and thereby to shield them from the contagion. + +The first experiments in the inoculation of _Tchouma_ or cattle typhus, +were made in the year 1853, by order of the government, in the +neighbourhood of Odessa, at the Heridin farm, by Professor Jessen. + +The first inoculative attempts were very fatal; they caused the death of +all the inoculated animals. But it was soon perceived that these +grievous results, far from prejudicing the theory, really confirmed it; +and that the virus, attenuated in its toxical properties, would prove as +effectual as was expected. And truly, in 1854 and 1855, at the Dorpat +establishment, the inoculations made with a better selected virus +afforded results less disastrous. At Kozau they were still more +satisfactory. In fine, passing from experiment to experiment, they +arrived at the conclusion that it was necessary to inoculate several +heads of cattle, the one after the other, without having recourse to any +other virus than the first inoculated, so that they might thereby obtain +virus of the 2nd, 3rd, 4th, 5th, and up to the 10th generation. The +virus thus attenuated in its morbid effects answered at length every +experiment, and oxen thus inoculated could mingle with impunity with +diseased cattle. + +At the veterinary establishment of Chalkoff they inoculated, during +eight meetings, 1059 animals with virus of the 3rd generation, and the +results were as satisfactory as could be wished for, only 60 animals +having sunk under the effects of this preventive operation. + +The inoculations made in 1857 and 1858 on an estate belonging to the +Duchess Helena, at Karlowska, in the government of Pultawa, and +conducted by the veterinarian Raussels, likewise afforded the most +satisfactory results. + +Professor Jessen thinks it certain, that beasts born of cows which have +been afflicted with contagious typhus do not contract the disease. He +maintains that Europe may be preserved from this frightful scourge, by +taking care that no cattle be exported from the steppes of Russia save +those which have had the distemper either naturally or by inoculation, +and he is striving to propagate this opinion, and to render it +practical, by having all the cattle inoculated, without exception. + +It is deeply to be regretted that counsels so prudent have not been +heeded in the 47 governments which, out of the 53 possessed by Russia, +have generated the contagious typhus; for then it would not so +frequently have effected its passage into the neighbouring states, and +England most probably, would not now have to take up arms against its +fatal extension. + + +VII. + +We here conclude that part of our labour which includes the history of +this disease, and what we have been able to glean from those medical +writers, and others, who have given us the results of their experience. +It may have appeared somewhat protracted, but it has at least laid open +to the student the antecedent investigations of our predecessors, under +calamities of the same kind, but considerably more fatal than what has +yet been witnessed in Western Europe during our time. We have +disinterred and brought to light the forgotten works of conscientious +and competent men. Like Brunelleschi, the architect, we have sought, not +to invent a theory, but to recover a practice; and thus we have received +the observations and precious facts, and finally the preventive +treatment, of other men and other times, which had coped successfully +against the cattle disease when its ravages were infinitely greater. + +To resume, then: these inquiries (which we undertook without +anticipating so rich a harvest) have proved, and made evident-- + +That the contagious typhus afflicting horned cattle, has spread its +destructive principle over our globe ever since there have been animals +living on its surface. + +That from century to century, not to say from year to year, it has +carried its terrors amidst nations and peoples. + +That the remedial measures which had been taken and applied prior to the +middle of the eighteenth century, were utterly powerless either to cure +this disease or to prevent it. + +That at that period appeared two English physicians, men of remarkable +aptitude and penetration, one of whom, Malcolm Flemming, laid down in +theory the bases of a preventive treatment; whilst the other, Peter +Layard, applied this theory to practice, by inoculating sound and +healthy animals with the morbid virus of the typhus, in order to protect +them from the fatal effects of the contagion. + +That this all-important progress in medical experience, has been +absolutely forgotten; so much so, indeed, that the experiments of +inoculation, tried in Russia only ten or twelve years ago with perfect +success, do not seem to be connected by any link with those made in +England a century before, and that the invasion of the so-called +CATTLE PLAGUE in 1865 seemed to some men to have introduced a +new scourge, which men were not armed and prepared to meet--which they +were powerless to cure, or to stay in its progress. + +These inquiries, then, have proved, we think, that we are not so +helpless as we had imagined to resist the evil. But we cannot help +feeling, that we have laid bare in this exposition some most distressing +inferences concerning the human mind. For, in truth, can anything be +more deplorable, than thus to see the civilized nations of Europe +endure, from century to century, these reiterated outbreaks of cattle +typhus, and to see likewise that no man of sufficient energy and +independence has yet arisen to tell the truth fearlessly to the +governments and peoples, however painful that truth may be, and to +expose the futility of the measures hitherto employed to arrest the +scourge? + +And, on the other hand, is it not most afflicting to see discoveries of +indisputable value buried out of view, submerged in public libraries, +utterly unknown and forgotten, like their authors, to such a degree, +that the distemper which they have made known in its entirety, and which +is as old as the world itself, seems to us almost new in 1865? + +God send, that these cruel trials and severe lessons which the past has +bequeathed to us may teach us something for our benefit! May the +irresistible might which is derived from the auspicious union of capital +and intelligence supersede the vain and flimsy efforts of isolated +energy! May the government, which lavishes hundreds of millions upon the +destructive engines of war, devote some portion of its ample means to +the study of hereditary infections and contagious diseases! For these +fatal epidemics decimate men as well as cattle, and we may at least ward +off from our children the desolating disease which at present afflicts +ourselves. + +We possess already every requisite means to protect ourselves from the +formidable visitation of these diseases: we have science; we have the +men who cultivate and teach it; we have the experience of the past +added to our own. To-day, we are called upon to resist the baleful +effects of cattle typhus; but another epizootia may come to-morrow, and +strike our horses and our sheep--those domestic animals which constitute +our most precious possession. The cholera hovers about us. If we do +nothing, if we talk and debate instead of acting, these scourges will +come upon us on a sudden, and find us quite as helpless as ever to +resist their sway. + +These palpable truths deserve to be further developed, and will be +treated more copiously at the end of this book. They will constitute the +complement of our work, necessarily written in haste, since the danger +we had to expose was itself so urgent and alarming. + +FOOTNOTES: + +[A] To assist the researches of other inquirers on this vital subject, +now so generally interesting, we may add, that the cattle treatises +already referred to--of Malcolm Flemming and Peter Layard--are to be +found in the Library of the British Museum, bound together in a single +volume, which is certainly worth ten times its weight in gold. It +contains, indeed, eight different opuscula, all relating to cattle +complaints, which scientific students may consult with real +gratification. I will here transcribe the titles of the most important +of these treatises, the pregnant expositions of the two English +physicians above-named. + +That of Malcolm Flemming: + +"A Proposal, in order to Diminish the Progress of the Distemper among +the Horned Cattle, supported by Facts. London, 1755." + +That of Peter Layard: + +"An Essay on the Nature, Cause, and Cure of the Contagious Distemper +among the Horned Cattle in these Kingdoms. London, 1757." + +A great many accounts, treatises, and expositions on the same subject +appeared at the same time in France, Holland, Denmark, and Switzerland. +One, which appeared in the last of these countries, is entitled: + +"Reflexions sur la Maladie du Gros Bétail, par la Société des Médecius +de Genève. 1756." + + + + +SECOND PART. + +This Part is divided, as already stated, into four chapters. + + + + +CHAPTER I. + +_On Typhous Diseases in general, and the Typhus which affects the Ox in +particular._ + + +By following the example of those authors who have described the +contagious typhus of the ox, we might proceed at once to explain its +symptoms, and go directly to our purpose; but, by taking this hasty +course, we should expose ourselves to be imperfectly understood by the +majority of our readers, and to leave certain doubts in the minds of +physicians as to the nature of the disease and the propriety of its +treatment. + +All animals, including man himself, are born with a predisposition and +liability to contract a certain number of contagious febrile diseases; +they bear in a manner a certain number of physiological elements, which +might be called latent germs, and which, under given conditions, become +the leaven of these diseases. This must, indeed, be the case, since +after these disorders have been once developed those who have been cured +of them are not apt to contract them again, the morbid developments +having destroyed that natural aptitude which had previously existed to +undergo the morbid action of the contagious virus. These diseases are +not numerous; they constitute a very distinct class, and the same laws, +which regulate the phenomena in one of them are applicable to all the +rest. + +These diseases exhibit the following characteristics: 1st, a period of +incubation, during which the whole economy, more particularly the blood +and humours, experience very important changes and modifications; 2nd, a +febrile state, which varies in its continuous or intermittent types, and +in its intensity, according to the species of the animals, and which +proceeds from the alteration of the blood; 3rd, a revulsion at once +toxical and congestive towards the nervous centre, inducing _stupor_; +4th, a flux of mucus from the mouth and chest; 5th, a more intense, +congestive, and inflammatory flux or discharge from the external or +internal teguments--the skin or the mucous membrane of the digestive +channels; 6th, a period of adynamia and dejection, with a tendency, in +some cases, to a critical or salutary rejection of the morbid matter by +the development of tumours or abscesses in the skin; 7th, they are at +once infectious and contagious, epizootic or epidemic; that is to say, +they are transmitted in different degrees by contact, by inoculation, +and at a distance by the means of vitiated air; 8th, finally--and this +is their leading characteristic--_they are not subject to recurrence_, +each individual that has once been affected, losing in general all +aptitude to contract the disease a second time. + +This last characteristic, when well understood, ought in reason to +induce us to have recourse to the preventive treatment, and such has +been the case with respect to the most virulent amongst them--small-pox +and the typhus of the ox. + +Prompted by these principles, which are as logical and fixed as any +mathematical deduction, I suggested in 1855 that inoculation should be +applied in typhoid fever, which is nothing else but the equivalent of +intestinal small-pox, in order to prevent the disease in men. But if the +simplest truth sometimes requires a contest of ages before it is heard +and understood, I could not hope to fix attention on a fact which might +be taken as problematical. I felt that I was outrunning time, and that I +should neither be heard nor understood; and so it has proved. + +Be that as it may, these typhous diseases have, as is seen, their laws +and foreseen development. They attack animals generally, but chiefly +herbivorous animals, endowed, as we have shown in the first part, with a +vital resistance which is, relatively speaking, very inconsiderable. + +These febrile typhous diseases (whether their development is caused by a +spontaneous morbid action in the patient or by an evident contagion), +have a period of incubation during which the vital strength undergoes +latent morbid modifications, though not sufficient to indicate, save in +times of epizootics and epidemics, the particular form which is about to +reveal its symptoms in the course of a few days. This period of +incubation being over, the mouth and chest become affected, and fever +declares itself; and then the _materies morbi_, which is to become the +special and dominant characteristic of the distemper, is directed either +to the skin, or to the digestive mucous membrane. In the first case, we +see evidence of exanthematic diseases, which present only the lightest +forms of detersive disorders, such as measles, scarlatina, or that more +serious one, from its pustulous form, the small-pox. In the second case, +the elimination takes place from the intestinal canal, and then we see +produced in animals, as well as in men, the typhous diseases: that is to +say, the typhoid fever--a pustulous and ulcerous malady of the +intestines--or the common typhus of the hospitals, prisons, and +campaigning armies; and again, in animals, there is also the typhus of +the steppes, of the marshes, &c. + +The Eastern pestilence, the plague of Rome in the age of Antoninus and +the plague of Athens, which might have given to Hippocrates the right +of treating with Artaxerxes as one potentate treats with another, ought +perhaps to be classed among those typhuses not subject to recurrence. + +As for the _cholera_, it seems to be a contagious and epidemic disorder, +of a distinct and particular kind. We are ignorant of its essential +cause, its nature, and its mode of treatment; and although it has +prevailed in every age, and even frequently of late years, it will +always, by reason of the strange formation of our medical institutions, +find us as weak and defenceless to resist its attack as we have ever +been. + +If we have been properly understood, typhous diseases are, above all, +general febrile affections. At one time the _materies morbi_, or +discharge, affects the skin; at another, the digestive mucous membrane. +When it acts upon the skin, as clinical observation shows, there is +sometimes a sort of hesitation in the eruptive process; people wonder +what disease is coming forth; the eruption wavers in the form it will +assume, till at length its real character is determined. The same +uncertainty prevails when the intestines are affected. Sometimes the +exanthema is merely the equivalent of simple measles or scarlatina of +the intestinal mucous membrane, and many typhoid fevers of short +continuance are nothing else in their nature. The same occurs in common +typhuses. Sometimes the local affection proceeds as far as pustulous +eruption, sometimes only to exanthematic rubefaction; hence the various +alterations which we have witnessed in the intestines of cattle killed +in our presence at the slaughter-houses of the Metropolitan Market, and +which we ourselves dissected. The experienced Professor Bouley, from the +Ecole Vétérinaire of Alfort, near Paris, whose visit must have been +beneficial to England, clearly recognised in an ox which was slaughtered +and dissected at the Metropolitan Market, the genuine pustule of typhoid +fever. But in most cases, as we shall show, it is the other forms which +prevail. + +We make these observations in order to anticipate the objections of +those reasoners who, being more influenced and guided by the local facts +and by the symptoms, than by the general phenomena of comparative +pathology, might argue that such or such fact is opposed to our +doctrine. + +In a word, then, typhous diseases have their types; but the living being +is subjected to so many different influences, hereditary, idiosyncratic, +climataic, hygienic, &c., that by the side of one subject going through +the course of morbid phenomena with fatal regularity, another may be +seen in which such or such functional derangement is readily +distinguished. Thus in some animals, predisposed thereto by prior +disorders, the morbid action originally propelled towards the channels +of respiration will continue to be most salient; and after dissection +the lungs will be congested and emphysematous, and the intestines +relatively but scarcely altered. The animal, indeed, though bordering on +typhus, will sink under the effect of functional derangement in the +breathing passages. In others, by the influence of some particular +predisposing cause, disorders of the nervous centres will be signalized; +a cerebral and spinal pains will be intolerable, delirium will quickly +ensue, and the asphyxiated patient, if a man, will succumb in the course +of a few days; or if an ox, he will be wild and ungovernable, and then +fall as if thunderstruck, fastened to his stall. Finally, in other +cases, these first two phases of the distemper will not prove fatal, the +intestinal injuries will pursue their course, and the affected animals +will not die until the third period. + +As we have seen, the morbid phenomena may be different, although the +affection continues the same; the typhoid fever or the typhus being +nevertheless the essential disease which prevails. + +These generalities, to some readers, may appear irrelevant, but let them +not be mistaken; they have a claim to our notice, and are really +important. They show, indeed, that independent of the preventive +treatment, which is an absolute rule in the case of virulent, +contagious, and non-recurring diseases, the treatment of the disease +itself, when it has declared itself, and when it pursues its course, +cannot be the same for every patient; and that, moreover, this treatment +must vary in the different phases of the disease, as physicians and +veterinarians are well aware. + +These generalities, likewise, explain the various diseases--viz., those +in which the animals blend together the typhous and exanthematic +diseases. The measles and the scarlet fever, affecting the external or +internal membranes, are like the first steps of these maladies; they are +generally slight, and we have but to watch over the progress of the +symptoms, and to assist nature, which, with few exceptions, brings all +things to a favourable issue. + +These disorders, which are relatively slight and do not provoke in the +economy any of those changes which in some sort transform the +constitution, are not absolutely proof against relapse. They lead us +rationally and by degrees to the more infectious and contagious +diseases, to the common typhus; therefore it is unnecessary to apply the +preventive treatment to them, that being exclusively reserved for the +latter. + +Let it then be well understood, that the typhus of the ox, the study of +which we are about to enter upon, may vary in its symptoms and +post-mortem appearances, without losing thereby the characteristic mark +which renders it a thoroughly distinct, and, in the present day, a +thoroughly well known distemper. + +Now that the reader possesses these general notions of the Contagious +Typhus, we shall be able to speak to him in a language which he will +understand, and give a definition which he will be able to judge and +appreciate. + +The typhus of the ox, then, is a _virulent, contagious, febrile, and +non-recurring disease, with stupor and derangement of the nervous, +respiratory, and digestive functions; leaving various changes in the +respective organs of these functions, and chiefly in the intestines_. + +This new definition seems to us to be more faithful and just than those +hitherto given; and this, if needed, we could demonstrate. + +I do not disguise from myself that some of the opinions expressed in +these generalities may, at first sight, appear strange and liable to +objection. Thus, it may be argued that inoculation as a preventive +treatment of typhous maladies is far from being a general law, +applicable to every case; since in Russia, for instance, where this +inoculation is practised every day, it completely fails in certain +foreign herds, and they die of the consequences of the operation; and +that this, therefore, might happen in England. + +To these objections we would reply, first, as regards the novelty of +opinions expressed, that we have taken up the pen, because we had to +write something different from what has already been published in known +works, otherwise it would have been our duty to remain silent; and +secondly, as regards the inefficacy of inoculation, that organic and +vital phenomena have their principles and their laws, which are fixed +and invincible, from which it is reasonable to deduce consequences and +positive rules of conduct, which cannot yield to superannuated opinions +or imperfectly executed experiments. To institute experiments indeed +under the rigorous conditions of a logical and irrefutable +demonstration, is not so easy a matter as may generally be thought. + +For our part, the principles deduced from strict observation are the +basis on which we build, and if it so chance that we are baffled in our +experiments we vary them indefinitely; and if still we are deceived in +our hopes, we ascribe the miscarriage to our impotence, to inadequate +means, and to the defective instruments which the physical and chemical +sciences, still in their cradle as regards organic matter, supply for +our use. Above all, we wish it to be remembered--"_Scribo nec ficta, nec +picta, sed quæ ratio, sensus, et experientia docent._" + + + + +CHAPTER II. + +_The Origin and Causes of the Ox Typhus._ + + +I. + +I have drawn my conclusions as to the preventive treatment of typhus in +the ox, from the knowledge I had acquired of its morbid phenomena, its +nature, and its non-recurrence; and it is a logical deduction quite as +accurate as could be the result of a syllogism. The study of the origin +of this typhus, and of the causes by which it is generated and spread +abroad, will supply us with additional arguments to sustain this +deduction, as well as those signs and indications which are the very +foundation of curative treatment. The description of the disease will +contribute to the same result; for the rational treatment of a distemper +can be derived only from a knowledge of all the phenomena which occasion +it, of the functional derangements, and of the alterations observed in +bodies after death. + +I wish particularly to say at once, in entering upon the subject of +etiology, that the special works which treat of it contain precise +information as to the causes and origin of the typhus in horned cattle; +and that the chief organs of the press in every country--those ephemeral +encyclopædias in which unfortunately so much vital force and +intelligence are dissipated--have published articles of the highest +interest on this subject. It would be physically impossible for me to +begin again a bibliographical labour similar to the one exhibited in the +First Part, in order to afford due justice to each of these public +writers, who have met the epizootia on the confines of their country and +fought hand to hand with it. This work is not susceptible of so much +enlargement. Let it be well understood, that I claim no other merit than +that of discussing these questions of etiology, in that order and with +that common sense which fix ideas firmly in the mind--which, if I may +use the term, _photograph_ them on those parts of the brain allotted to +the memory and judgment; also of drawing from known and admitted facts +more rational and practical conclusions than those which have been +current up to the present time. + +Much has been already said and argued on the origin of the contagious +typhus which affects the ox; some adhering exclusively to the special +conditions observable in the breed of those oxen which are reared and +fed on the steppes of Russia and Hungary; others, more reasonably, as it +seems to us, ascribing it to the hygienic conditions generally, that is +to say, to the climate, the season, the feeding, &c., &c., amidst which +these animals are living. + +All these discussions upon what has been said and argued on this subject +have been very useful. For, had it been rigidly proved that the oxen of +the steppes, by some peculiar organization, carry within them those +germs or physiological elements which at given times become the leaven +of the distemper, and, at a subsequent period, the elements of the +contagion, then, indeed, a fact of capital importance and prominent +authority would have been established, and the attention of all men +interested in these inquiries would have been exclusively concentrated +on that particular race of animals and on those countries smitten with +the curse, in order to arrest and confine the disease within its one and +only focus. + +The supporters of this theory, concerning the first circumscribed origin +of the typhus, maintain that all the epizootics whose deplorable history +we have given in the first part of this work, have had no other +generative causes than the propagation of the complaint, born and +begotten on the banks of the Wolga and the Danube, and subsequently +conveyed to the different parts of the earth by the emigration of the +cattle. And in this manner, too, they have accounted for the appearance +of the typhus in South America, in Africa, and in Asia. + +Since this doctrine on the origin of the typhus has been conceived and +maintained by men of a high order of understanding, we must suppose that +they had been struck and convinced by important facts and serious +reasons; and as it would be unfair to oppose a plain denial to an +opinion now so generally adopted, we are bound to say in what manner +these authors justify their views, after which we shall endeavour to +refute them. + +The partisans of the circumscribed origin, who make it depend +exclusively on the peculiar organization of the race of the steppes, +have based their argument, peremptory and unanswerable as they imagine, +on the prime fact, that it has always been possible to trace the +diffusion of the typhus in a given country, to some sick animal of the +steppes conveyed to that kingdom. In this manner it is, that they +explain the generation of the epizootics which have so frequently wasted +the continent of Europe. On whatever point of the globe they may appear, +this, and only this, is the source of their existence. The isolated +position of Great Britain is made to support their arguments. "Behold," +they exclaim, "Great Britain, which, thanks to its surrounding seas, has +escaped most of the epizootics which have desolated France and Germany +during the early part of the nineteenth century." Nay, more, the present +visitation of the distemper is also seized upon to sustain their theory, +since certain oxen, natives of the steppes, appear to have imported it +into London. + +We must add, that nothing is wanting in order to prove this assertion; +for they relate with perfect regularity, and step by step, the course +taken by the contagion; they specify the time occupied on its passage, +and even the names of the infected vessels which have thus imported the +principle of the typhus. + +It must be admitted that all the facts thus stated are indisputable; we +acknowledge as true, that the bovine race of the steppes has conveyed +into other countries the contagious germs of the disease; we admit that +its dissemination may be thus accounted for. + +But to admit this fact, and to draw from it the conclusion that the +bovine race of the steppes alone is capable, by some particular and +distinct organization, of developing the original typhus of the ox, and +that this typhus has no other focus on the earth than the banks of the +Dnieper and the Don, does not appear to us a sound logical deduction. +And as, if this conclusion were positively recognised, we might see but +one side of the evil, and deduce very serious consequences therefrom, it +is necessary to receive these facts for what they are worth, and no +more. + +Let us first observe, that those writers who ascribe the contagious +typhus to the race of Southern Russia, do not take into consideration +the epizootics of this typhus, the account of which has been handed down +to us by the ancient authors of Greece and Rome; and that they refer +just as little to those which are quite as frequent in the republics of +South America as on the banks of the Dnieper. For even if we allow that +once, and only once, one of these epizootics may be traced to the +arrival of a ship containing oxen brought from the steppes, how, on the +other hand, can we believe that all other epizootics have had such a +fortuitous cause to generate it; consequently, the typhus, in these +cases, must have been locally developed and diffused among American +cattle? + +Moreover, we seek in vain for the reasons which would authorize us to +assign to the bovine race of the steppes a particular organization, +rendering it alone fit to engender the typhus. But let us grant for a +moment, that the Russian and Hungarian oxen constitute a peculiar race, +as their framework and the length of their horns would seem to imply; +this much being conceded, it still remains to be shown in what respect +their anatomical and physiological structure differs from that of other +animals to such an extent as to render them alone liable to originate +this fatal typhus. + +Oh! if it were true that the bovine race of the steppes alone could +engender the typhus! we would hail the fact with joy, and would show +without much exertion of reasoning that, in that case, we possessed not +only the means of preventing the disease by inoculating sound and +healthy cattle, but the far more important means of sweeping it for ever +from the earth, by at once exterminating that cursed race, smitten with +the original predisposition of this plague; and as, after all, the +murderous scourge of the typhus of the steppes has already cost, and may +perhaps continue to cost the various nations of the Old World millions +upon millions, they would feel that their most urgent interest would be +to come to an understanding (nor would the sacrifice be too much for +their resources) so as to destroy and extirpate the evil at its original +source. There would then be no difficulty in raising up a new breed of +cattle in those countries, by transporting to it those of other nations +free from the infection. + +But who does not understand that this heroic sacrifice would be +illusory, and that the foreign races, modified in time in this new +medium, would regenerate the typhus; so that the double sacrifice of +extermination and indemnity would have been made to no purpose? + +We wish we could adopt this hypothesis, so simple and so consolatory, of +the circumscribed origin of the typhus, and its exclusive propagation +through the race of the steppes; but our mind is altogether opposed to +that view, and for the following reasons, amongst others:-- + +If the bovine race of the steppes alone could produce the typhic virus, +by reason of a particular organization which is the prime condition of +its existence, _this race alone would of necessity be fit to receive its +taint_ by the influence of contagion. But if the other animals of the +same species, as unfortunately too surely happens, can receive the +principle of the disorder, develop the ailment, and die of its effects, +then the reasoning of our opponents is faulty from its source; and it +must be admitted that all horned cattle are apt to generate the typhic +virus in those countries which afford the conditions of its production, +and that this exclusive predisposition as it is called, attributed to +the race inhabiting the steppes, is simply a chimera. + +But arguments are seldom exhausted even to defend a bad cause, and it is +objected that the fact that all oxen may contract the typhus transmitted +by the contact of animals from one to another, does not prove that the +original predisposition is the same in every race; and they persist in +maintaining--1st, that the typhus of the steppes is alone able +originally to beget the disease; 2nd, that having thus begotten and +produced it, it becomes, after this organic conception, apt to be +transmitted to every animal, and fit to be assimilated with them. + +To these subtleties and argumentative refinements it would be as easy +for me to oppose abstract reasonings equally strong, as it would have +been for the Jansenists and Mollinists, had it so chanced that they had +been drawn into a debate on the origin and nature of the virus of the +plague which carried off Jansenius. But let us confine ourselves to +serious facts and conclude-- + +1st. That we have no proof of any anatomical and physiological +difference in the humours or in the blood--that is to say, in the +organic, intimate, and biological elements of the individuals which +collectively constitute the bovine species. + +2nd. That we have a right to believe, that all horned cattle are apt to +develop the typhic virus when they are placed within the conditions +required for that effect--that is to say, when they are exposed to the +special morbific causes which form its condition _sine quâ non_, and +which are met with on the banks of those great rivers which water +Southern Russia and Hungary, in Africa, on the banks of the Nile, in +South America, on the margins of the lakes, and in what are called hot +climates, &c. + + +II. + +But if the origin of the typhus cannot exclusively depend on the +peculiar organization of certain individuals of the bovine species, we +must inquire after and search for the real causes which produce it. + +We have explained already, in the First Part, what alterations organic +matter undergoes in general, when accidental causes happen to modify its +organic elements; and we have pointed out the fact, that of all living +creatures herbivorous animals were those that offered the least vital +resistance to the causes of disease and destruction. + +This unquestionable fact being taken for granted, let us now consider +under what conditions live the multitudinous herds of horned cattle +which in Russia and in South America are reared and supported solely for +the produce of their flesh, and sometimes, too, for that of their hides. + +The great breeders and proprietors fix the number of their heads of +cattle according and in proportion to the quantity of the pastures, but +like other men, they mortgage the future for their benefit without +making due allowance for accidents or extreme changes of weather, as +when years of unusual drought succeed those of heavy rain; so that these +herds, by the single fact of these extreme fluctuations in the degrees +of temperature, are exposed to a multiplicity of causes productive of +disease. The same nature which generates life and health generates +disease and dissolution, and when the former are neglected the latter +will prevail. + +In the prosperous and favoured countries of the temperate zone, such as +England and France, these extreme variations in the seasons, which are +always the cause of a deficiency or alteration in the production of +fodder, are equally the cause of the numerous epizootics which attack +all the herbivorous species, and particularly those to which oxen fall +victims, such as the tumourous typhus (_le typhus charbonneux_), the +so-called aphthous fever, the contagious peripneumonia (which is not +liable to return and is prevented by inoculation), parasitical cutaneous +disease. + +But in less favoured countries, in those which are damp, argillaceous, +swampy, inundated by the overflows of their lakes and rivers, or by the +reflux of the sea, there is deposited a slimy or brackish water, which a +temporary torrid heat afterwards causes to ferment; and then a +superabundance of life, a teeming vegetation, springs up in all +directions. In the midst of this swarming vitality live and thrive an +infinity of worms, maggots, animalculæ, insects, mollusca, fish, +reptiles, birds, &c.; and here, too, all these creatures die and decay, +when this slime, the prolific source of generations which we might look +upon as spontaneous, begins to dry up and disintegrate. Then from these +organic vegetable and animal matters, in a state of decomposition, +escape those deleterious gases, such as hydrogen, carbonic oxide, +nitrogen, carbonic acid, sulphuretted hydrogen, and even phosphoretted +hydrogen. + +Often to all these causes of infection are added myriads of +grasshoppers, which cover the ground, where they die, aggravating the +mass of pestiferous vapour which fills the atmosphere. Finally, the +water which slakes the thirst of the herds of cattle is corrupted; the +plants on which they feed distil poisons; the air, the water, and the +plants, carry within them a principle of venom and death. After this, +how can we be surprised if this flood of putrid emanations is +transformed into a contagious typhic virus, whose subtle and +pestilential effluvia are conveyed by the ox to considerable distances? + +In fine, let us recapitulate in our minds all the causes of destruction +to which these passive creatures are exposed, and we shall acknowledge +that there is no necessity to attribute to them a peculiar organization +in order to understand the development of the typhus, which, at a given +moment, cuts them all off; and that in the deltas of the different +countries, as well in Asia, Africa, and America, as in Europe, are to be +found those conditions of infectious disease which we have described. In +these causes, and only in these causes, or in those which resemble them, +will rational men seek for the principle of the contagious typhus in the +bovine race. + +Moreover, who is there who does not understand that what is true with +regard to cholera is likewise applicable to this contagious typhus? The +cholera, for causes analogous to these, subject to the particular state +of the soil, is generated, not exclusively, it is true, but most +frequently, on the banks of the Ganges, in the same manner as the +contagious typhus is developed in certain countries where its natural +focus is found. + +The race of animals which exists on this deadly and destructive soil is +an instrument of incubation for typhus, not in consequence of their +peculiar structure, but because the conditions under which they live +condemn them to this fate. + + +III. + +Now the breeding of cattle, and the feeding and fattening of them for +the market, constitute a branch of industry--a great interest. They all +have to be removed, conveyed to various distances, and sold; so that +this traffic becomes a new cause to be added to all those which foster, +develop and propagate the distemper. + +In prosperous times, when the seasons, conformably with our wishes, have +pursued a course which we call regular (for we are fain to believe that +the planets turn on their axes on our account), and when the cattle find +the ground covered with rich pastures, and limpid streams--conditions +which are eminently favourable in themselves, though in Hungary it is +necessary to add gum, salt, mineral water, and arsenic acid, before the +health of these animals is satisfactory,--then the cattle breeders make +their sordid calculations, and select the heads of cattle intended for +sale. + +With animals, as with man, health is but relative, not absolute; the +healthiest in appearance often bearing within its frame the fatal +principle of no distant death. Fatness not being by any means a sure +sign of vital strength, many of these cumbersome beasts, though +seemingly in good and sound condition, contain in their systems, in +various stages of incubation, the tainted leaven of contagious +affections, such as peripneumonia, or even the typhus itself. + +But, regardless of this liability, their sale and migration are resolved +upon at length. Hitherto these harmless creatures have lived in the most +perfect stillness and retirement. Their calm, monotonous life has been +as regular as the course of time; never by a single pulsation have their +hearts exceeded the wonted number per minute; they are all gifted with a +nervous sensibility of which the vulgar have no notion. Some favoured +few have felt the sympathy of friendship for the herdsman who tended +them, and for the companions with which they fed. They have been leaders +of their own herd, they have marched at their head; they have given the +signal when to seek shelter beneath the trees, or when to repair to the +brook. They have loved the fields amidst which they have grown and +thriven. Some of them, reared and fed beneath the domestic thatch, were +grateful for the care they had received; their master was endeared to +them, they would run to meet his coming, answer to their name, and lick +his hand with fondness. + +And it is the course of this tranquil, this happy existence, that is +about to be broken abruptly. It is this creature, the pattern of +gentleness and goodness, that we are going to treat like a heap of +insensible and inert matter--which we are going to subject to +unutterable torture! + +And now, indeed, these creatures are all at once handed over to the +savage guidance, to the thongs and cudgels, of a hind, whose cruelty +keeps pace with his stolid ignorance, and who abets his dogs to quicken +their course to the neighbouring market. From this moment, half-fed and +athirst, these poor animals are forced to make long journeys afoot; or +since the construction of railways, to be heaped together confusedly in +a locomotive pen. There, the shaking, the sudden starts, the friction of +five hundred wheels on the rails, the horrid snorting of the engines, +alarm and terrify them to such a degree as to turn the whole mass of +their blood. + +In such a state of vital prostration or feverish excitement, entire +herds are carried to the public markets or to annual fairs with other +animals, and nearly all sent to the shambles. But some amongst them are +reserved for another fate. The females, for instance, are set apart to +serve as milch cows; and in this manner they carry with them into the +cowsheds, wherein they are received, the taint of those contagious +distempers, the germs of which lay concealed in their frames, or which +they have contracted from the companions of their journey. + +Some of these heads of cattle, starting from the steppes of Russia, have +to travel five hundred miles in an open cage, less cared for and +protected than bales of merchandise, exposed to the rain, to the heat +of the sun, to sudden changes of temperature, to cold and cutting +draughts, increased by the rapid motion of the train;--these animals, +foundered, prostrate, panting with fever and torturing pains, still have +to undergo new trials, if they cross the sea. In this case, the wretched +victims are violently expelled from the locomotive, rocking sheds of the +railway; a leathern strap hanging from a crane lifts them into the air, +and lets them down into the mid-deck of a ship, where they are crowded +as closely together as possible, for here, too, space is very costly. +Finally, the vessel gets under way and ploughs the ocean; contrary winds +beat it about in every direction, and these poor creatures have to +endure a new kind of torture, accompanied by the intolerable pangs of +sea-sickness; and in this state it is that they alight on the British +soil, and are driven off to the different markets. + +It is useless to expatiate at length on the state of general derangement +and disease in which these oxen reach their final destination. Some +amongst them have endured for eight or nine days these unspeakable +tortures, without being sustained by nourishment--for no animal, when +his spirits forsake him, can assimilate his food amidst all this +physical suffering and so great a shock to his nervous system. + +Let us here declare that these animals, though removed from their +meadows with all the signs and appearances of sound health, at a time +when a fine season had been productive of abundance, and when no +epizootia was raging in the country which they have left, may +nevertheless bear within them the taint of contagious typhus; and let us +ask ourselves what must come to pass in those disastrous years when this +typhus prevails under the influence of those destructive causes which +were passed in review just now, and when the Russian and Hungarian +proprietors, eager to forestall an inevitable general calamity, hasten +to send off to Italy, France, Holland, Finland, or to the ports of +England, many animals already seized with typhus, and whose virus must +have acquired infectious properties still more intense and deadly under +the influence of the deep disquiet and commotion which the removal and +conveyance of these animals, under conditions so deplorable, must have +produced in their frames. + +Such are indeed the pernicious conditions in which oxen may be, and +often are, dispatched to England; and such appears to be the real cause +of the outbreak of the spreading epizootia which we witness at this +moment, and which has created so much alarm in so many counties of +England.[B] + + +IV. + +Let us now consider this contagious typhus in its destructive extension +over the British soil; let us study and examine the causes of its +diffusion as they pass under our notice. + +The mooted question of determining whether the cattle typhus was +originally imported from abroad, or whether it broke out spontaneously +in England, has been, and still is, a subject of dubious debate amongst +some professional men, amongst the leading writers of the public +journals, and also amongst agriculturists and farmers.[C] + +And, in truth, the propagation of the distemper is occasionally +witnessed under conditions so singular and striking, that it seems to +warrant and supply arguments for every conceivable opinion. + +When the disease was recognised and identified for the first time on the +24th of June, 1865, public opinion ascribed its appearance to contagion +arising from some diseased cows imported from Finland, and which, after +being exposed in the Islington Market on the 19th, were sold and removed +to the cowsheds of a breeder or dairyman. + +We may observe that, on hearing the intelligence of this sudden +invasion, the public mind, which is so excitable in England, did not +disguise the indignation it felt against foreign countries which had +been capable of contaminating an island so advantageously situated and +so well protected, and infecting her magnificent herds, exuberant with +health. But after a closer examination of the facts, and possibly +alarmed, at the serious consequences of a Continental blockade which +would deprive the United Kingdom, not of the entire twenty or thirty +thousand live stock, such as oxen, sheep, pigs, &c., which they receive +every week, but only of the eight or ten thousand head of cattle which +are landed weekly on their coasts to supply their markets, public +opinion was appeased. But, unfortunately, this national susceptibility +now took the opposite extreme; and the only causes it now saw were the +dirt and want of adequate ventilation in the metropolitan stables and +sheds; and to these causes it attributed, first the generation, and then +the propagation or diffusion of the malady; an opinion which appeared +all the more natural and reasonable, in that the oxen and cows of the +graziers were the first victims of the typhus. + +We all know how liable, among all nations, the public mind is to waver +and fluctuate, and how susceptible and open it is to new impressions +during fatal visitations and general calamities; nor can we feel the +least surprise at the uncertainty which has so long prevailed, and still +continues, as to the real causes of the introduction of the bovine +typhus in England. + +Let us therefore examine this question of etiology, and try to discover +what opinion ought to prevail. + +It is important to establish at once two material facts which seem to us +indisputable: + +1st. That the contagious typhus in cattle which is known to be permanent +in the southeast of Europe, actually existed there during the month of +June, 1865; 2nd, That some of the horned cattle, fed and reared in that +part of Europe, were transported to England, after having crossed +through Russia from south to north, in order to avoid passing through +Germany. + +As for the first of these facts, it is admitted and received, as might +easily be proved by reproducing the speeches and addresses delivered by +the veterinary doctors at the Congress now being held at Vienna, and at +which were present the men whose experience of this cattle distemper +gives them the highest authority--Hertwig, Jessen, Röll, Siegmund, +Gerlach, &c. + +The contagious typhus of horned cattle is so fully in the epizootic +state in those countries which are washed by the Black Sea, that it was +enough for the veterinarians present at the Congress to manifest a +desire to see cattle afflicted with this disease, for the opportunity so +to do to be immediately afforded them.[D] + +Thus, then, the fact is undeniable, the contagious typhus was raging, in +June, 1865, in Hungary and Russia, as it rages there at all times. + +As for the conveyance of cattle from those countries into England, the +fact is no less certain and assured. It is well known that a convoy of +300 heads of cattle, proceeding from the pasture-grounds of Hungary and +Austria, was transported into Finland by rail, and afterwards shipped at +Revel for England. Thanks to the rapid locomotion by steam, the +migration of these cattle had lasted but ten days--two days for the +transport by land, and eight days for the passage by sea, through the +tortuous line of the Baltic; but this was sufficient length of time for +the incubation to be produced, even supposing the animals to have looked +sound when their transit began. + +Moreover, it is indubitable that the markets of this immeasurable London +have for many years been supplied with horned cattle from every country: +from France, Holland, Belgium, Podolia, Poland, Prussia, Austria, +Hungary, and Russia. + +Thus, the Islington Market (the fact is assured) had received horned +cattle imported from the countries where typhus is known to be +permanent. Were these cattle thus imported affected with the typhus? +This fact likewise is as certain as the other, since two of the foreign +cows thus imported, were the first to fall sick, and to die of this +typhus. + +But if the contagious typhus of horned cattle rages permanently on the +banks of the streams which discharge themselves into the Black Sea, and +if the beasts reared in those countries have long been transported to +England and other countries, how, it will be asked, is it that the +disease has not broken out more frequently, for it has never been seen +in Great Britain, at least, during the former part of the nineteenth +century? + +This question is not devoid of a certain degree of importance, and +deserves to fix our attention for a moment. + +Now the conditions in which the animals were exhibited in 1863 and 1864 +were precisely the same as those of 1865, before the outbreak of the +disease; and yet the contagion has been possible in 1865, whilst it was +not so in 1863. + +We do not presume to explain the mysterious phenomena which govern the +development of epidemics and epizootics; but it seems to us not +altogether impossible to give a rational and satisfactory elucidation of +the facts. + +In general, in _epizootics_, and I might even say in some particular +epidemics--in that of the typhus, for instance--three connected and +inseparable facts form the condition _sine quâ non_, of the generation +of the disease. First, a focus for producing the virus; secondly, for +the most part a favourable soil, and a special predisposition amongst +animals to receive and propagate it; thirdly, what is called an epidemic +or epizootic genius--that is to say, a particular state of the +atmospheric elements, or the air, which hitherto has escaped our +analyses, and whose morbific properties vary in their degrees of +intensity. Thus the epizootic genius of 1711, the terrible one of 1750, +and the one which now diffuses its contagious miasma, have differed in +some of their virulent conditions. + +However that may be, it will be sufficient to glance back at the past to +assure ourselves that, in general, epizootics have been coincident with +some violent change of season, such as extreme droughts, or +superabundant rains; that is to say, when the cattle, disturbed in the +physiological conditions of their health, have become favourable to the +incubation of the miasmatic leaven scattered through the air, or else +when these animals were living under irregular conditions, and had to +endure unwonted fatigues and privations, as in the folds of campaigning +armies, for instance. + +These epizootics have appeared to depend not only on the state of the +soil and of the health of the cattle, but also (we repeat it designedly) +on an element no less indispensable to the propagation of the disease--a +special state of the air, which favours the development and preservation +of typhic miasma: for sometimes a sudden change of temperature has +proved sufficient to stop the rampant progress of the contagion, the +other conditions remaining unaltered. + +These relations of cause and effect between the contagious principle, +the predisposition of the animals, and the state of the atmosphere, +evidently are subject to some exceptions; but we must allow that in the +present epizootic they are absolutely and completely applicable. For, in +truth, the years 1864 and 1865 have been distinguished, if not by the +persistency of a high rate of temperature not often witnessed, at least +by an excessive drought during the months which are both hot and rainy; +and this has happened in the various countries of Europe, thereby +producing a falling off in the pasture and fodder both as respects their +quantity and quality. + +As to England, a country usually cold and damp, but renowned for its +spacious green fields and meadows, it has suffered more than any other +country from these unfavourable conditions, and their destructive +influence on the grass and corn; the herds having found a great +reduction of food where formerly they met with abundance. Everybody has +seen, as we have ourselves, large herds of cattle, wandering in +amazement from field to field, and seeking for something to browse on a +parched and arid soil. A supplementary provision of corn, roots, malt, +and the grounds of the beer vat or spirit barrel, no doubt served to +mitigate the sad effects of these privations on the health of cattle; +but in spite of all that could be done, their blood became impoverished, +their strength and vital resistance sank, and (like the animals which we +transferred at will into a soil more favourable to the spread of +parasitic diseases), they afforded last June, as they do now, an unusual +predisposition to suffer and transform the morbific principles of +typhus, which in all probability they would have been proof against at +any other time. We may very fairly infer this much, for we must of +necessity believe that the regular importation of cattle from those +countries which are considered as the permanent focus of typhus, has +from time to time transported the miasmatic germs of this malady into +England, although the virus did not take effect on British cattle at +those periods, for want of one or other of the conditions necessary to +its generation and development. + +We may likewise infer, and a watchful appreciation of the facts +contained in the veterinary medical journals would show that this +opinion is not unfounded, that the special disease which constitutes +this typhus (similar in that respect to epidemic diseases), may develop +itself in one beast by accident, spontaneously, sporadically--that is to +say, without immediate contagion; in a word, _apart from those epizootic +conditions which alone render its propagation possible_. To be brief, we +think that an isolated case of cattle typhus may by chance be detected, +when there is no epizootia prevailing to account for it, just as we +occasionally meet with cases of typhus or cholera among men during +seasons absolutely free from these epidemics. It would not, therefore, +appear to us altogether impossible, that under the influence of very +special conditions, the contagious typhus of the ox might have its birth +in England; and this would favour the theory of those reasoners who +maintain that this typhus met with the first causes, and the origin of +its development, in the stalls and cowsheds of London. But such has not +been the cause of cattle typhus in the epizootia which we see at +present. + +No doubt some animals suffered great privations, but, whatever +alteration their health may have sustained, all this is nothing to be +compared to the sufferings endured by the cattle in the steppes under +the influence of deleterious conditions of the most exceptional +character, which do, indeed, give birth to this typhus, and which we +have already described. + +No, certainly not! _Nothing authorizes us to believe that the typhus now +under our observation was bred and born, at first, within the stalls and +cowsheds of London._ It was most assuredly imported. But it is true, +nevertheless, that this cruel scourge found the horned cattle of England +predisposed to receive it, and it likewise met with atmospheric +conditions favourable to its subsequent diffusion; in a word, it met +with the epizootic genius proper for the generation and propagation of +the typhus miasma. + +It is thus that we may account for and reconcile the two contending +theories, one of which refers the cause of this typhus to foreign +importation, whilst the other insists that it originated in the filthy +and half-ventilated cowsheds of the metropolis. + +But if this typhus could not spring up spontaneously out of the bovine +race of England, it must be confessed that, independently of the general +predisposition due to a great and protracted drought, it found in the +sickening sheds of the metropolitan and country cattle the most +favourable conditions for its incubation and subsequent diffusion. + +It would, indeed, be difficult to conceive of anything more directly +adverse to the hygienic laws of health in cattle than the stalls and +sheds dotted over the densely populated districts of London. Most of +these pent-up cribs are situated in narrow lanes and yards, in filthy +streets and blind alleys; and within these close, hot, and steaming +receptacles the miserable cows, pressed against each other, without +ever moving a limb, waste away and become phthisical in a very short +space of time. We may readily imagine what a prey to the contagion must +be afforded by these animals, already more or less ailing, some of which +are fed in a great measure on malt, so sour and acrid that the very +smell of it is intolerable. The milk from these cows is, moreover, of so +wretched a quality, that in a cowhouse containing 48 of these poor +creatures, at Kensington, I found only one, the milk of which exhibited +the taste and quality fit for a sick child, for whom I ordered a milk +diet. + +It is not, therefore, to be wondered at that the present epizootia, +during this late tropical season[E] especially, should have met with all +the conditions most conducive to its development and propagation. + +When the cattle distemper first broke out, the graziers, not suspecting +its gravity, attempted to treat the animals themselves, but soon +afterwards perceiving the fruitlessness of all their remedial measures, +they felt that the best thing they could do was to turn their sick +beasts to whatever account they could, by driving them to market or to +the slaughter-houses, an expedient which they were the more disposed to +adopt, inasmuch as the diseased cows had ceased to give milk. And then, +the removal of these animals, in various stages of the disorder, became +the most rapid means of disseminating the contagion, which, had it been +concentrated and pent-up at first within its narrow focus, would +otherwise have spread with less fearful havoc.[F] + +In the meanwhile the sick cows being commingled with thousands of heads +of cattle exposed for sale at the different markets, communicated far +and wide the principle of the disease; and as a certain number of these +animals remaining unsold were driven back to the farms, into stalls +until then removed from every cause of contagion, they introduced among +their sound companions the fatal germs of the distemper; and as, again, +this effectual means of propagating the evil was repeated several times +in the same week, the consequence was that, by the end of July--a little +more than a month after the outbreak--the whole of the south of England +was in some sort contaminated. Thence the contagion extended to the +north of the kingdom, and passed into Scotland; so that, at present, the +cattle-typhus has spread its ramifications over a great number of the +counties of Great Britain.[G] + +In the first instance, the contagion spread from animal to animal by +means of an infecting influence in some degree direct, among cattle +sheltered beneath the same roof, or collected in swarms within the same +markets. But very soon the air itself was impregnated and polluted by +the vaporization and diffusion of the typhic miasma; and herds of cattle +which had no contact, either direct or indirect, with infected animals, +were seen to be tainted with the distemper. Whether this contamination +was produced by the passage of attainted cattle along the public roads +(having fields on the right and left), or otherwise, nothing but an +absolute isolation, an utter impossibility of contact, appeared to offer +a perfect immunity against the spread of the evil. + +The miasma, condensed by the fogs and transported in all directions by +the winds, now began to overleap every natural or artificial barrier, +and the favoured herds, ruminating at their ease in the manorial farms +of the wealthy patricians, in their well-kept parks and amid every +luxury, were suddenly smitten with an evil which in their case seemed an +anomaly. In such peaceful homes these innocent creatures were tended by +intelligent and benevolent hands, which understood and felt for their +frail constitutions; food of the best quality was lavishly supplied to +them, and whatever they could wish for lay around them in abundance; +richly reared, they had themselves become so many ornaments within these +scenes of beauty, and all men thought that here, at least, were plots of +rural ground which the genius of epizootia would not invade, and in +which the healthy herds were invulnerable to contagion. + +It was under these circumstances that the fine farms of Earl Granville, +at Golder's Green, skirting the Finchley Road,[H] containing as many as +130 milch cows, were suddenly and fiercely attacked amidst their +seeming immunity, and struck down in great numbers. + +"When I left England a month ago," said the noble lord, "there were +about 130 milch cows in four sheds; in the two largest and best managed +I found only one cow yesterday, September 4th." + +The park of Holly Lodge,[I] which is partly bounded by the main road +along which pass and repass files of cattle going to and coming from the +markets, was visited by the same unsparing scourge. Now certainly, the +noble and beneficent lady of the manor, who secured to her cattle every +attention, and who, confiding in the resources of medical science, +attempted every means to save these stricken creatures doomed to an +inevitable death; she whose enlightened mind, equally open to the claims +of science as to those of misfortune, desired that experiments should be +made which might tend to throw any light on this devastating malady; +she, at any rate, one would think, might have escaped the common lot +without exciting wonder or envy at the privilege which she enjoyed. But +this fell and sweeping epizootia, inexorable in its latitudinarian +march, entered those shady bounds, and decimated those orderly sheds +with the same impartiality as it did that of the poor man, Cutting, +whose whole fortune was stored up in the two milch cows whose death he +had to deplore. + +This epizootia threatens to invade, one by one, all the European States, +like the awful scourge of 1750, to which we have already drawn +attention. For even now Holland and Belgium[J] have been smitten; and +the alarm it has excited has for a time superseded the panic which the +stealthy advance of the cholera to the west had kindled. Some imagine +that it might have been kept out of Great Britain, or have been checked +in its outbreak. But, in spite of all the safest precautions and the +soundest measures of preparation, it would most likely have baffled +human skill, and neither been held aloof nor stifled in its focus. But +how painful it is, to have to write and to think that ignorance, +carelessness, revolting cupidity, and the most wanton violation of the +laws, have all contributed to extend the evil, with the foulest +premeditation and the blindest disregard! + +To feel one's self a stranger in a country, and to be able to rejoice at +one's connexions with it, and at the same time to be obliged to give +publicity to certain truths distasteful to those to whom they are told, +is a most painful task. But, as it would be to swerve from that duty and +loyalty which the national interests as well as those of science impose +upon a writer, not to speak out with impartial justice in a matter of so +vital an importance, we beg permission to consider, without reserve, +this delicate question:--the causes which have contributed to propagate +the complaint. + + +V. + +England, so long spared by that wasting scourge, which had so often +extended its ravages over France and other kingdoms during the last +sixty years, was taken by surprise; and the regulations and laws +necessary to stifle without delay the distemper in its focus--that is to +say, in the metropolis--not being in readiness, the outbreak of the +disease found her helpless and unarmed. + +On the other hand, the organic forms of the English Government and +municipal bodies, the reserve of the Cabinet during the vacation, the +limited power of the Lord Mayor and his civic counsellors, the +subdivision of London into parishes and vestries, as in the good times +of the middle ages, the loose scattering of the shambles and meat +markets through the many streets of the huge town, the right asserted by +each man to be absolutely independent and free, the sanctity of the +Englishman's home, &c., &c., all concurred to let loose and propagate +the contagion, instead of keeping it within bounds. + +Indeed, whilst the competent authorities, with all the energy which +could be expected of them on so grave a matter, were meeting and +discussing the best measures to be taken, and the interesting debates at +the Mansion-house were throwing the first light upon the question, the +insidious malady pursued its destructive progress, diffusing new terror +and alarm. When at length the Privy Council issued their orders, +prescribing the public declaration of sick cattle, and that no affected +beast was to be conveyed either by rail or by ship, whilst all the +necessary means of purification and disinfection were to be employed, +&c., it was unfortunately too late, the dreadful calamity having taken +root and multiplied its stem like the upas-tree. + +What a field for reflection there is in these cases, which originating +with the imperfect state of the laws and institutions, have fostered and +encouraged the disease! But this is a subject which it would not behove +us to discuss, and we prefer to show by the notes which will be found +appended to the end of this work, and which are produced as attesting +documents, that cattle proprietors, by their own confession, too often +sacrifice the interests of the public to their own private advantage.[K] + +Nor have we been able to participate in the thoughts and reflections of +so many sensible and judicious persons, on the impotence and +dilatoriness of the public authorities, and also, let us say, on the +inadequate pecuniary means proposed by a people so lavish of its wealth +when useful and great undertakings are designed, without paying a +natural tribute of regret, to the memory of a Prince who took so deep an +interest in the progress of agriculture, and who, had he still been +living, would have known how to direct with a firm and steady hand, the +right measures to be taken amidst so many intricacies and +embarrassments. + +Sometimes allusion has been made to France in the speeches delivered at +these meetings, presided over by that active magistrate, the Lord Mayor. +In the course of these remarks the speakers have praised and held up to +admiration the advantages of her system of centralization, the decrees +of her sanitary police, and the promptness with which she executes the +measures which the public interests require. That is true. France is +certainly in a state to resist the scourge with very effectual means to +arrest its progress; but if in this matter, as in some others, she have +acquired a superiority, it has only been by an experience dearly +purchased, these epizootics having returned more than once to destroy +her flocks and herds. Politically, the same might be said of her +revolutions, those great moral epidemics. + +An orator, a writer, went so far as to say, in one of his numerous +letters, the one dated the 24th of August: "I regret to say some of our +neighbours laugh at our expense."[L] + +No, your neighbours will not laugh at your misfortunes. They sympathize +at present both in your joys and sorrows, and if I have taken up my pen +on this occasion, it has only been because I could not look with +indifference on your too just anxieties, when I flattered myself that I +might write some useful pages to mitigate and relieve them. + +As most newspaper readers are aware,[M] and as everybody may easily +ascertain, the diseased cattle, in spite of reiterated orders to destroy +them immediately, were, nevertheless, driven to the markets to be sold +for what could be got for them; or when their tainted condition was too +glaring they were at once sent off to the private shambles, the owners +of which, in order to disguise the accusatory proof of the misdemeanor, +hastened to sell the body of the animal. It would be quite impossible to +mention all the violations of the law, which every day continue to fill +the columns of the public journals. One graceless wretch, who deserved +to be hanged for it, if his ignorance do not excuse him, was so infamous +as to introduce a sick cow into a shed not yet attainted, in his +criminal desire of propagating the disease there.[N] + +Thus, then, independently of the causes inherent to the typhus itself, +which served of necessity to diffuse it, other causes proceeding from +the defective state of the law, and the perfidy of individuals, have +contributed to its dissemination. And yet the Government circulars, the +newspapers, and the reports of veterinary doctors have made known that +the slightest omissions and inattentions were serious--that the want of +ventilation and cleanliness in the stables, the overcrowding of the +cattle, and their abiding near their own droppings, or dung-heaps--that +the keeping of dead bodies close to farms, cowsheds, enclosed grounds, +and fields--that the hasty and imperfect burial of cattle--that the +collection and transit of their fragments, bones, horns, and skins--that +the driving on the public roads of any animal either tainted itself, or +having lived among those that were sick--that the clothes of persons and +stable utensils, soiled with putrid liquids--that all these, and similar +causes, were capable of propagating or aggravating the disease. + +But whilst we must loudly condemn the voluntary misdeeds of those who +drove their sick cattle to market, it must likewise be allowed that, to +conform one's self rigidly to the given injunctions, was sometimes +attended with serious embarrassments. How great, indeed, must have been +the perplexity of any grazier who, being the owner, for instance, of +forty head of cattle, and having seen ten of them perish under his eyes, +without knowing where to dispose of them, was threatened with the loss +of the remaining thirty within a few days! How could he calmly and +patiently resign himself to suffer so large a quantity of animal matter +to accumulate and putrefy around him, when, suddenly ruined, and +destitute of every resource, the authorities held back instead of coming +to his assistance. + +The prime cause of all the transgressions committed in despite of the +Privy Council's orders, may therefore be referred in part to the want +of compensation to be granted to the owners of infected cattle. It all +might be almost reduced to a question of money. For let us suppose for a +moment, that inspectors entrusted with adequate powers, had been +authorized, after a close examination, to point out the tainted cattle; +to fix a moderate price on them by way of compensation; to have them +slaughtered, carried away, and immediately buried, would not such a +course have diminished the generation of contagious miasma in a +considerable proportion? + +Moreover, some cattle-breeders and farmers exposed themselves to the +imposition of fines and penalties without any evil designs; for when +they drove their beasts to market they were only in the stage of +incubation, at the preliminary period, when it is really no easy task to +distinguish the distemper. The following fact will exemplify this. + +At each market, in spite of continual warnings, the inspectors pick out +and despatch to the slaughter-houses a certain number of sick cattle, +not only those affected with typhus, but with other disorders. One +cannot help wondering, on seeing the poor, lean, sickly condition of +some of these creatures, how their owners could have been so mad as to +expose them for sale; but in their number there are a few which, +although sick, appear in good health to the common observer. + +About a fortnight ago, during one of our visits to the great +Metropolitan Market, Mr. Tegg, the veterinary inspector, whose +intelligence and earnestness are quite equal to the very difficult +charge with which he is entrusted, ordered to be seized and removed to a +secluded fold near the slaughter-houses, a dozen diseased animals. When +once these cattle had been thus collected in a body, it was easy to +submit them to a still closer examination. Most of these beasts, adult +cows and oxen, were lean, panting, feverish, dispirited, and remained +motionless where they stood. But among them was a cow, with a brisk and +lively look, a quick open eye, which watched us with anxiety, and fled +at our approach every time we passed by her. The turn came for this cow +to be examined. Mr. Tegg, strong and handy--as every good veterinary +doctor should be--seized hold of one of her horns, but he was quickly +shaken off; other persons came up to assist him; the fiery animal was +suddenly seized by both horns, by the nostrils, and the tail; but so +strong and spirited was the animal, that she defended herself with +advantage against all her adversaries, and once more shook herself free. + +It was necessary, however, to master the creature, so they surrounded +her again, pressing her back this time into a corner of the pen, to +overpower her. But lo! the animal takes a sudden spring, and leaps over +the bars. Assuredly this cow, for a beast suspected of the typhus taint, +had given a proof, if not of health, at least of extraordinary vigour; +and her owner, who had seen her condemned with much vexation, now +thought he saw ample reason to reclaim her, and drive her back to the +market for sale. However the cow, on taking such a leap, and under +conditions so unfavourable, came down with all her weight upon her +limbs, fracturing one of her forelegs. + +After this accident, we were able to prosecute the examination we +desired, and Mr. Tegg showed us a row of little glandular swellings on +the ridge of the gums, and livid spots on the vaginal mucous membrane, +which confirmed his diagnosis. The owner of this cow, nevertheless, +still discredited the diseased state of the beast; so to convince him, +she was driven off at once to the slaughter-house to be struck down; +but, unfortunately, three or four others filled the required area, so +that the poor cow was forced to witness the execution of her +fellow-creatures before being killed herself. The look and posture of +this cow, her excited yet terrified glance as she surveyed this scene of +carnage, was one of those pictures which no pencil could draw; and +although we acknowledge that man possesses an incontestable right to +apply to his own use the dead or live matter of animals for his food and +sustenance, we could not help feeling for the poor victim, slipping over +the blood, and thus scenting death before receiving the stroke. + +We are not excessively sensitive; we have seen a hundred horses bleeding +from the incisions made by veterinary pupils, and scores of oxen +slaughtered; we ourselves have practised numerous experiments on +animals; but the affecting sight of that animal witnessing the slaughter +of others, and waiting her turn to die, touched us deeply. We could not +help asking ourselves, how it was that man could dispense with +compassion and good feeling even in that bloody toil, and why he did not +bandage the eyes of the doomed creatures he was going to sacrifice? +These dumb animals that we treat like inert matter are sensitive like +ourselves; they are very conscious of pain; and if it be our privilege +to compute the number of our days, we ought not to forget that they are, +like us, endowed with intelligence, so that when they are thus detained +at the place of execution, all their senses and faculties being +concentrated on their destroyer, they are fully conscious of the cruel +fate which awaits them. + +At last it was the poor beast's turn to be slaughtered, and ten minutes +afterwards we opened her entrails, and had proof that Mr. Tegg's +judgment was exact, for already the stomach and intestines offered to +view indubitable signs of the typhus at its first period. + +The owner of the cow was then convinced and brought to reason, but he +still very fairly asserted the goodness of his motives, about which none +present doubted at all, and applied for compensation to the full value +of the beast, both as butcher's meat and offal, which application was +granted. + +Judge, therefore, by this particular example, how many tainted cattle +there must have been which have propagated this distemper, some with and +some without the knowledge of their owners; and, "_horresco referens!_" +how much of this tainted meat must have been purchased and eaten by the +public, since this cow had all the appearance of health and vigour, and +the real diseased condition might not have been detected at all, but for +the experience and sagacity of Mr. Tegg, the inspector. + + +VI. + +In this consideration of the causes of the contagious typhus in bovine +cattle, we have deemed it essential to invite attention both to those +which are generally recognised and admitted, and to those which, though +they may have been settled in the minds of observant and experienced +men, may yet appear hypothetical to certain readers. + +Besides which, in every scientific work, allowance must be made for the +past and future; and here we have two vital distinctions. If the man +who undertakes this task does not go on, he falls back; and it was to +avoid incurring this reproach that we have passed our old boundaries and +visited new avenues. We are aware that more than one objection might be +urged against the opinions and theories which we have exposed, in order +to account for the outbreak of typhus in England; we might anticipate, +we might reply to these objections; but we would rather recapitulate our +inquiry into the causes, in the tangible form of practical propositions. + +From the general considerations above given, we think we may conclude, + +1st. That the causes which generate the cattle typhus on our globe are +permanent and unceasing, not only on the banks of the great rivers which +empty themselves into the Black Sea, but also in other countries--in +America, in Africa, &c.; wherever, in a word, exist the conditions, not +of race (the race of the animal in this case being but secondary), but +of climate and of the organic elements which are indispensable to the +formation and development of typhic miasma. + +2nd. That the cattle typhus, although it exists not necessarily, but +through the improvidence or want of caution in man, on different parts +of the earth, never appears at all in the temperate and more genial +zones, save under particular and special circumstances, analogous in +some degree with those which generate the human typhus--inclemency of +the seasons, overcrowded dwellings, bad or insufficient food, and want +of cleanliness; and that these particular and special circumstances give +birth to the epizootic genus, rendering the cattle fit and apt to +receive the germs of the contagious virus, and to foster its incubation. + +3rd. That the cattle typhus, thus accidentally developed in the +temperate and genial zones, by means of the vicious hygienic conditions +amidst which horned cattle are accustomed to live, and which serve as +the causes of its propagation, is afterwards transmitted by the contact +of animals living in the same stall or shed, or collected in herds on +the same ground, or transported in the same vehicles, by land or sea. + +4th. That the droppings of animals, their litter, their dead bodies, and +their detritus, or broken-up remains--also the stables, vehicles, and +implements which have served for their use, and all matters or +substances which have touched them or approached them--are generative +elements of the distemper. + +5th. That the typhic miasma, thus reproduced and multiplied in one place +under the influence of all these producing causes, is conveyed by the +winds to great distances, smiting those well guarded cattle which +appeared to be fully protected from the possibility of infection by +their isolation. + +6th. That the want of prompt and stringent measures first to +concentrate, and then to stifle this typhus in its focus; the love of +lucre, the perfidy of some, and the absence of foresight and caution in +others, may be, and have been in the particular cases which we are +dealing with, material causes and agencies of its diffusion. + +Such we consider to be the causes which engender and propagate cattle +typhus, and which will serve as a basis for the preventive measures to +be employed in order to withstand and check its propagation. + +FOOTNOTES: + +[B] We are aware that the transport of cattle is conducted in a +different manner during the prevalence of this epizootia. The account +given by two German veterinary surgeons of the management of the vessels +of the North German Lloyd's, and of the manner in which the animals are +treated, is a proof of this; but before the appearance of the epizootia, +the transport of animals by land and by sea left much to be desired. +This account will be found at the end of this work (NOTE A); and all +documents in support of the facts which have served as the basis of our +dissertation, are also in the Appendix, arranged alphabetically in the +form of notes. + +[C] See Notes B, C, D, E. + +[D] See Note F. + +[E] On the 15th of September, the thermometer stood at 80° Fahrenheit. + +[F] See Notes G, J. + +[G] See Notes K, L. + +[H] See Note M. + +[I] See Note N. + +[J] See Notes O, P. + +[K] See Notes R, S, T. + +[L] See Note V. + +[M] See Note Y. + +[N] See Note Z. + + + + +CHAPTER III. + +_Description of the Contagious Typhus of the Ox; its Symptoms, Course, +Progress, &c._ + + +I have already written the history of the typhus which affects the ox; I +have shown and dwelt upon the signs and characters of typhus diseases +generally, deducing therefrom the denomination and definition of that of +the ox in particular; finally, I have described the causes which +generate and diffuse it abroad. + +Now, I must make known the various phases and alterations to which the +disease is liable, and which, in the language of the medical schools, +are called its symptoms and characteristics; its progress or course; its +prognosis; its _post-mortem_ appearances, &c. &c. + +This examination, like those which have preceded it, will afford new +foundations for medical practice. + + +I. + +_Symptomatic Characteristics._--The typhus of the ox, like all +infectious and contagious diseases, offers to observation four +successive changes: 1st, a _period of Incubation_, during which the +original structure is subject to internal and latent derangements; 2nd, +a _period of Initiation_, during which the first evident signs of the +disease are manifested; 3rd, a _period of Endurance_, during which the +phenomena are fully developed; 4th, a _period of Decline_, or wasting +atony. + +These divisions and classifications, it will readily be conceived, are +rather fanciful, for nature does not adapt herself to our methodical +forms. Still we shall abide by them, because they have their relative +and practical utility, and because they will afford to the practitioner +suggestions more easily understood; and finally, because the organic +changes are different at these various periods, which in their entirety +constitute the typhus of the bovine species. + +The description of those different phases through which the organism of +cattle smitten with the contagion has to pass, has moreover been given +in a masterly manner by the veterinary physicians of the different +European countries, especially by those in which opportunities to +observe it have been most frequent--that is to say, by the Russian, +German, and French veterinary doctors, Jessen, Röll, D'Arboval, Gellé. + +The English physicians of the 18th century, as we have already seen, +were also in no respect inferior to those of our own time. Finally, Mr. +Simonds, who published a very able Report on his return from his +scientific exploration in Galicia, in 1857, and the skilful Professor +Bouley, in his recent communications to the Académie de Médecine, in +Paris, respecting his examination of the present cattle typhus in +England, have described the disease with minute exactness, as we +ourselves have verified on the various sick beasts which we have seen +during the last two months. + +1. _Period of Incubation._--Several careful experiments, which have been +cited in the historical division of this work, and numerous fortuitous +occasions, have authorized us to assign a duration of nine or twelve +days to the period of incubation, according to the general conditions +of the epizootia, the manner in which the contagion is transmitted, and +the former state of health of the affected cattle. + +Thus an epizootia at the outset, either when it has become general, or +when it is at its decline, does not always transmit typhic miasma of the +same virulent intensity, nor does it always provoke in the frame a +labour of incubation which is invariable. The contagion transmitted from +animal to animal living continually in the same stalls or sheds is +followed by an incubation more quick and active than that which results +from a chance contact in the markets, or from a contagion produced at a +distance, by the transmission of the miasmatic effluvium along the +public highways. + +Let us add to these considerations the relative state of each animal's +health, and we shall then perfectly understand that the incubation must +vary both in its continuance and in the characteristics of its +manifestation. In some animals it scarcely betrays the derangements +produced by its morbid operation: they preserve their appetite and their +usual looks. A close and attentive observation would alone be able to +distinguish some slight alterations in their way of living, in the +regularity of their rumination and sleep. But in others, there is no +mistaking a something irregular and unusual in their appearance and +living; the vital state is no longer the same. Thus an animal which used +to be cheerful and familiar becomes silent and solitary; it browses the +grass with less eagerness and avidity; it lies down more frequently and +longer; it lingers by the side of the hedge along the field, or it +wanders about, here and there, with a listless look, and without any +object. Others moan and complain, bellowing at intervals in an unusual +manner, very expressive of languor and pain. + +But apart from seasons of epizootia, the beasts too often exhibit these +imperceptible shades of variety in their looks and actions for the +attention to be struck by them; these changes, therefore, are almost +always unnoticed. + +However, the typhic miasma absorbed at the same time by the respiratory +and digestive mucous membranes serves to modify the qualities of the +blood, and secretly reacts on the nervous system; soon after, the +animal exhibits more decidedly those changes which previously were +hardly to be detected; his want of appetite is more marked, his sadness +more obvious, and his attention fixes itself more slowly and carelessly +on the objects which surround him. When he is in the shed, his usual +food is found in excess of his wants, his thirst is much keener and more +frequent, and a continual dejection and lowness of spirits or a +transitory agitation disturb all his functions. When the farmers or +graziers notice these premonitory signs for the first time they pay but +little attention thereto; but if the contagion has found its way into +their stalls and sheds they are no longer deceived by them, but begin to +apprehend that in a day or two fresh victims will be added to the +number. + +2. _Period of Initiation._--Soon the elaboration of the virulent miasma +in the organic structure changes the quality of the blood and humours, +the functions of assimilation and secretion are modified, the nervous +centres receive vitiated organic elements and are disturbed in their +physiological conditions, and the smitten animal displays that state of +latent uneasiness which he is imperfectly conscious of by a general +look of heaviness and stupor (+Typhos+), which has suggested for this +disease its name of typhus. + +Indeed, the poor animal's eyes are fixed, the hearing becomes obtuse or +indifferent, as may be seen in the sinking of the ears, those organs +which are so sensitive, so contractile, and so vigilant in herbivorous +animals. With the head hanging down and motionless, the neck stretched +out, their forelegs open and spread, their buttocks drawn together and +one of them completely lax, they seem to succumb beneath the weight of +their bodies. In a word, the animal exhibits through its whole bearing a +heavy sadness, a general dejection, which bespeak a great derangement in +the whole structure. From this time, in the animals which are most +seriously affected, the appetite ceases, the rumination becomes +irregular and partial, whilst in some others the appetite and rumination +are maintained in different degrees. + +But the incubation of the morbid elements pursues its course, the +alteration of the blood becomes general, and the circulation is +increased and quickened. After this the fever interposes and stops the +secretions, that of the udders is dried up, the mucous channels cease to +flow, the mucous membrane of the mouth becomes whitish, the little +glands situated on it are more permanent, especially in the +circumference of the gums; the floor of the tongue and the larynx are +inflamed, the mucous membrane of the cow's sexual organs is red and +furrowed with livid streaks, the white of the eye is parched, and the +skin feels alternately hot and cold, as well as the horns and hoofs. + +Some of the sufferers have an external horripilation, transient +shiverings are felt in the front and hind quarters and at the junction +of the limbs with the trunk. Some pregnant cows near their delivery +miscarry. In a word, at this period of irritation, the whole frame is at +war with the typhic elements which besiege it, and which overcome the +preservative power of the vital forces, and from this general +disturbance arises an incandescent fever, which drains and stops all the +secretions at their source. + +These general symptoms are the first signs and warnings of functional +derangements more significant, which may, however, vary according to the +predispositions of each animal, and transfer their evolutions either to +the nervous centres or to the respiratory mucous membrane, or to that of +the digestive channels, in the inflammatory and febrile form of the +contagious typhus. Such at least is what we observe in the typhus of +1865 in England. + +The functional derangements, in truth, subordinate to and depending on +the predispositions exhibited by the cattle, are far from being the same +in all. In some, the nervous derangements predominate; in others, it is +those of the respiratory, and in others, it is those of the digestive +channels. + +As in this period of irritation the nervous centres are more +particularly affected, the animal suffers cerebral and rickety pains, a +constant cephalalgia, which provokes vague anxiety; he is sometimes +cheerful, sometimes wild and furious; he clenches his teeth and yawns, +the muscles of his face spasmodically contract, the spine feels very +sensitive when pressed, a burning and insatiable thirst comes on, the +breathing is hurried, and the intestinal evacuations are suspended. + +In this form the toxæmia appears to concentrate about the nervous +centres--as is observed elsewhere at the outset of certain violent +fevers, in the typhus and typhoid fever of man, for instance--and some +of their number may perish the victims of these nervous disorders, and +even fall as if struck with electricity. They die apparently from the +result of the typhic poison; for at this second period, we do not trace +in the nervous centres those injuries which might account for so sudden +a death. + +When the respiratory apparatus concentrates upon it the febrile +congestion, the breathing becomes painful, accelerated, embarrassed, +sometimes convulsive, and a deep, oppressive cough is heard from time to +time. The animal, under the yoke of this oppressive uneasiness, turns +his head from right to left, scents, and seems to question his flanks, +where the seat of the disorder is; and then, whether the pulmonary +affection is congestive or inflammatory or emphysematous, he may die of +the consequences of obstruction to the pulmonary circulation and from +the alteration of the blood, under the influence of a slow asphyxia, +but only at the third or fourth period. + +Finally, when the typhus localizes more particularly its morbid +phenomena on the digestive channels, we discern local alterations on the +floor of the tongue and the buccal mucous membrane, spots of livid red, +leaving behind them ulcerations of greater or less extent and depth on +different parts of the intestinal canal. In this form, which follows +more regularly all the periods, constipation is obstinate at the outset, +evacuation of the bowels takes place with difficulty, the fæces are hard +and the urine scanty, the belly is inflated and sensitive. + +Sometimes at this period of initiation, one of these three symptomatic +forms--the nervous, the pulmonary, and the digestive--may predominate +exclusively, so far as to mask the disease as a whole, and to constitute +it a special malady. But in that case, it is only the exaggeration of +the functional derangements which in their total constitute the typhus: +for when the distemper pursues its course, these three principal centres +of life are always affected in different degrees. Thus, not one of the +cattle smitten with the typhus goes through all the phases of the +disease, without suffering at a given moment in its nervous, +respiratory, and digestive functions. + +In this respect, the typhus of the ox presents an apparent analogy with +the typhoid fever in man, although it is different. Consequently, the +name of _typhus fever_ given by some veterinary surgeons, is not +altogether inapplicable to it. + +3. _Period of Duration._--At this stage of the disease, which may be +said to extend from the fourth to the seventh day, the nervous +derangements are confined to symptoms of uneasiness and sensibility +along the dorsal spine; for those cases which exhibited more violent +derangement in the nervous functions have proved fatal. In this period +of the disease the breathing is more embarrassed, particularly when the +pulmonary form of the disease prevails. The pulse, which is hard and +frequent, indicates from forty to sixty pulsations; the beatings of the +heart are more violent and audible; the mucous membranes, dry at the +outbreak, recover their secretions, but these latter are endowed with +irritating properties. Thus the eyelids, swollen and tumefied at the +edges beneath the lashes, drip with a corrosive liquid, which soon marks +its furrow along the chanfrin; the bronchiæ, the trachea, the nostrils, +the salivary glands, exude a serosity which runs out of the nasal and +buccal orifices. The exanthematic eruption having discharged itself +through the digestive channels, constipation is followed by diarrhoea, +rumination is completely stopped, the beast declines all solid +nutriment, and pants for drinks,--for those especially which have a +slight taste of acidity in them. + +The derangements at this period pursue a rapid course--the breathing +becomes more and more difficult, the skin is hot and dry, the hairs +stiffen more and more, gases are developed in the cellular tissues +beneath the skin, along the dorsal vertebræ, at the abdominal folds of +the posterior limbs and under the abdomen, in the form of flat, uneven, +crepitant tumours, which crackle when pressed with the hand; the +diarrhoea becomes more liquefied and irritant, for then it is no +longer a flow of droppings covered with mucus which is expelled, but +secretions already putrid, sometimes reddish in colour, and attended +with foetid gases, which induce tenesmus in the rectum, and force up +the tail. The animal grows perceptibly lean, his dejection is extreme, +and cows which are with calf miscarry. + +At night, the animal seems to have an increase of fever, sometimes of a +remittent type, after which he becomes drowsy and lies down to rest +himself or to sleep, if he can; but the difficulty of breathing, the +abdominal pains, soon force him to rise again, which he cannot do +without an effort. + +4. _Period of Decline and Sinking._--This stage is observed to extend +from the eighth day to the twelfth or the fourteenth. The morbid +functions pursue their course, for the disease has its regular phases +and a successive variation of phenomena. The secretions, which a few +days before were fluid and irritating, have undergone a change; they +have become thick and purulent, they flow more slowly from the ocular +mucous membranes, and also from the nasal and buccal, which are red and +inflamed, and they already emit a foetid smell. The dull tarnished +eyes become hollowed, purulent mucus lodges within their orbits, the +bronchiæ are stopped up, the breathing grows louder and more panting, +the animal instinctively stretches his neck to ease it; the wasting of +the flesh exposes the bones of the sacrum and coccyx, laying bare the +vertebræ and the ribs; the emphysematous tumours are more extensive and +crackling; the skin, less heated, wrinkles up and splits about the bony +protuberances; the udders are crusty and excoriated; detached boils, +hard and rounded at first, then soft and purulent, begin to show +themselves on the trunk and the upper parts of the limbs. The +diarrhoea, still frequent, becomes bloody and intolerably offensive. + +At this final period the organic structure yields to the effects of a +general alteration of the liquids and solids. The vital force has lost +the power of reaction; a mass of blood, decomposed by the double +influence of a virulent toxæmia and the obstructions of respiration, +conveys to all the organs a principle of dissolution; the nervous system +is in a manner paralysed, as is shown in the animal's insensibility. + +The secretions stop up the various channels and cavities; they lodge +within them; they undergo a putrid decomposition, and pass out with +difficulty in the form of a purulent and bloody flux, in the highest +degree infectious. Very soon the sick animal has ceased really to live; +it struggles and labours with its agony; if the lungs are clogged with +gas or fluid they rattle hurriedly and often; the animal cannot hold its +head up even when lying down, and when standing moves it to and fro as +if affected with the natural shaking of old age, and as if seeking to +ward off some indescribable evil, the occurrence of which it was +awaiting. + +The animal's body is a prey given up beforehand to the laws of organic +decomposition: the internal mucous membrane of the cheeks and lips peels +off in strips when rubbed; the sores on the skin have a livid and +gangrenous look; the eggs which the flies deposit on the edge of the +eyelids and at the nasal orifices, or on the excoriations of the skin, +quickly pass into the state of larvæ. The air they expire is cold and +infectious; the native caloric, extinguished in every focus +successively, disappears; the vaginal mucous membrane is tumefied, the +anal opening gapes, and from it flows a bloody and decomposed liquid +which the rectum can no longer expel. The mouth, half open and coated +with a thick glutinous foam, vainly tries to inhale long draughts of air +which can no longer reach the lungs. Finally, if the animal is lying +down, he expires in slow agony, his head borne down by its own weight; +or, if standing, he sinks and falls down, his death having anticipated +the fall. + +Such are the symptoms--the subjective signs which enable us to detect +the contagious typhus of the ox. But all animals do not exhibit these +disorders of the vital functions with the same regularity and excess. +Some of these we have seen, from first to last, sustain the internal +effects of the morbid process--in some sort passively--without revealing +any deep derangements in the nervous, respiratory, and digestive +functions. The poisonous virus had smitten them; they suffered in their +general structure; they looked stupefied; they lost, at a given moment, +their appetite and rumination; they had fever; their breathing had +become short and frequent; they had diarrhoea; they gradually lost +flesh, and the excreta passed through certain changes and +transformations. In a word, the animal had manifestly the bovine typhus; +but, thanks to a relative immunity, to a special organization, which +renders some of these beasts capable of resisting the contagion for a +long period, and sometimes altogether[O]--thanks to that variety which +we observe in different constitutions (for small-pox and typhus in man, +and the true typhoid fever in animals, do not operate with the same +violence on all alike)--thanks to this privileged organization,--we have +seen some oxen pass through every stage of the disease without +exhibiting this terrible train of morbid phenomena. + +In these cases--for even this mild form of the distemper at last +produces death--the injuries fix themselves more exclusively on the +digestive channels, and we witness, in dissection, ulcerations in some, +in others mere spots of a livid red, more or less extensive. + +Finally, although the typhus be one of the gravest maladies which +destroy and decimate cattle, all sick animals are not mortally affected +thereby. In the present epizootia, five per cent., as nearly as can be +ascertained, recover; and when that happens, signs of a favourable omen +are observable during the course of the attack. In these favourable +instances, indeed, the symptoms, even though they exhibit a certain +gravity, pursue a regular course; fever does not become remittent; the +fæcal discharge is copious and easy, with less foetor; the animal +loses flesh slowly and progressively; the tumours are cutaneous, +inflammatory; their character is good, depurative, and rather purulent +than gaseous and crackling. The droppings do not show that high degree +of pestilential decomposition described above; the animal in his drink +welcomes and digests a mixture of bran and flour; the secretions of +purulent mucus and the fæcal discharges dry up and stop in the early +part of the period of decline; the epidermis of the openings through +which they passed out peels off in thin scales, and afterwards in scurfs +or husks--in a word, the economy does not experience those acute +disturbances which strike one of the tripods of life--that is to say, +either the nervous centres, the lungs, or the digestive organs. + +Now, in these curable cases, in which the cure is most generally due to +nature's own efforts, but which a systematic treatment might render far +more frequent, the convalescence is long, and requires great attention +and a well-regulated diet, in which the food is carefully measured and +divided. Here there must be a rigid superintendence. A laxity in the +watchfulness, or too much reliance on the reviving health, have produced +sudden relapses, and been fatal to many sick cattle, which had been +looked upon as thoroughly cured. For it may well be conceived that +convalescent animals, after sustaining such violent derangements in +their health, and having been brought down to the lowest degree of +prostration and marasmus--to a reconstitution, we may call it, of the +solids and liquids--have a devouring hunger. If, therefore, the keeper +who looks after them unhappily forgets that the principal lesions or +sores are seated in the stomach and intestines, and if he gives them too +much solid nutriment, he impedes the cure, irritates the ulcerations not +yet thoroughly covered over, and soon adds another victim to those which +had already died. + +This convalescence lasts from fifteen to twenty days, and the animal +only recovers its health at last by slow degrees. Still the careful +keeper need not be afraid of a relapse when he is patient and watchful. + +Such, then, is the contagious typhus of the ox. Type of the unreturnable +infectious diseases, its virulent miasms undergo within the structure a +series of transformations: they produce in the frame a general disorder +fully capable of annihilating the predisposition or aptitude of the +animal to receive the taint. A disease essentially specific, it affects +the principal centres of life; it kills its victim both by its deadly +virus and by the local derangements to which it gives rise; for how is +it possible to preserve life when the whole nervous system, that +promoter and regulator of all the functions, is upset?--when the lungs +which revivify the blood, when the digestive organs which are the very +sources of alimentation, are smitten with stagnation?--when, in fine, +not only these vital centres have ceased to operate, but when each by +itself is the cause of torturing pains and exhaustion? + +The typhus, moreover, is observed in all animals of the bovine species, +whatever may be their race, their age, or their sex. The recovered +animals may live with impunity amidst diseased herds of cattle, thanks +to its non-relapsive nature. Jessen has even witnessed cows which, after +their own cure, communicated a sort of immunity to their offspring. For +the same reason it is that epizootias are less fatal in those countries +where they often occur, the constitutions of those animals which are +engendered amongst such habituated herds, preserving a prophylaxy +inherent to the blood which has been transmitted to them. + +Besides, what a pregnant subject is this for the physician, and what +more meritorious task can he set himself than the treatment of such a +distemper, which reason assures him must eventually lead to the cure and +eradication of the same complaint in the human species? + +From a cause which as yet has been indistinguishable and imponderable, +what important, what marvellous results loom in the future! The air +seems to us pure and wholesome, yet it conceals a typhic miasma of the +most deadly kind; it carries this pernicious principle into the richest +meadows, where we see feeding flocks and herds which to us seem +exuberant with health. Then this miasma is inhaled and absorbed, and it +meets in the frame the special and indispensable organic element which +is needed for its multiplication; there it undergoes certain latent +transformations, and a fermentation, a germination, which we call +_incubation_, in order to explain a process which we cannot understand. +Then fever is kindled, all the functions are disturbed, and the sick +animal is struck down, leaving us wondering, ignorant, and powerless +spectators in the presence of phenomena which, nevertheless, are the +eternal work of nature and have endured through all time.--But if in +the invisible typhic atom nature gives us death, it also gives us life +in the zoosperma. + + +II. + +_Lesions found in the Bodies of Oxen after Death._ + +The description which we have given of the disorders produced in the +different functions by the operation of the typhus, may easily suggest +what must be the lesions exhibited by the organs of the body. + +Death, we have said already, may overtake the disease at any of its +periods, and thus show every aspect and every degree of the organic +lesions. Such an animal being struck down at the period of initiation, +will not, of course, present the changes and varieties of the period of +decline, and _vice versâ_. + +In general, the state of the dead bodies is that of the most decided +marasmus; the remains are intensely repulsive, as well by the stench +they emit as by the sight they afford; and, in summer especially, +decomposition sets in with great rapidity. Consequently, the utmost care +is required in conveying them from place to place; and this attention +is the more essential, because in the transit, the cavities being +deprived of their contractile power, let flow the pestilential liquids +which they contain, thereby infecting the carriages and public roads. +The urgent necessity there is to inhume at once these dead bodies, the +most active agents in diffusing the contagion, is equally the drift of +this observation. + +The deceased animal, as a subject of anatomy, enables us to certify the +seat of the emphysematous tumours, and to see that they are really due +to the air which insinuates itself into the cellular tissue, and which, +receding from the pressure of the fingers between the cells, produced +the crackling sound we noticed above. This penetration of the air is, +moreover, a far more general effect than was supposed. + +It is ascertained, likewise, from the examination of these subjects, +that the round, fluctuating, and smaller tumours, are indeed purulent +gatherings, which occasionally find a passage into the layers and +interstices of the muscles. + +The muscular flesh is usually flabby, bloodless, unsightly, of a very +nauseous smell; and it would be difficult to imagine that the most +avaricious trickster would dare to offer even the most presentable parts +of it for sale and consumption. But when the expedients and artifices +known to the butcher's trade are had resort to, when, regardless of the +public health, the unprincipled dealer selects the most fleshy parts, +when he dresses and adorns them by colouring them over with the blood of +a healthy beast, the unwary eye of the purchaser may be deceived. +Observe, that we are now speaking of cattle that have died in the last +stage of this marasmus, so that we might suppose, even if the many +summonses before the magistrates, and the too moderate fines which have +been imposed on the guilty parties, had not shed the broadest light upon +the fact, that _a large number of sick cattle which had been slaughtered +at different stages of this frightful disease, have been dressed and +adorned, exposed for sale, sold, and eaten by a very large portion of +the inhabitants of London and of the country likewise_. + +_Digestive Channels._--The mucous membrane of the buccal cavity is, for +the most part, of a livid whiteness; ecchymosed stains, and sometimes +ulcerations, differing in their form and number, are visible on the +floor of the tongue. Mr. Simonds has had an anatomical model +constructed, which presents a perfect type of these ulcerations, some of +which are of a scarlet hue, with perpendicular edges. The _stomachs_ +exhibit a variety of ulcerations. + +The _paunch_, or first stomach, always contains a large quantity of food +intended for rumination; sometimes these aliments are dry, and lie +sticking to its sides; at other times they are diluted with water which +had not yet been absorbed after drinking. The inner membrane of this +first reservoir may show flat spots, with livid injections of different +sizes. + +The _honeycomb_, or second stomach, generally exhibits the same injuries +as the paunch. + +The _manyplies_, or third stomach, contains between its laminæ hard, +pulverulent, and dry alimentary substances, which are seen sticking to +the different leaves. On removing these substances, some ecchymosed +spots are laid bare, the epithelium of which easily peels off; +sometimes ulcerations, and even perforations, are visible. + +The _reed_, or fourth stomach, whose sides are thicker, more fleshy, and +more vascular, exhibits within its folds various kinds of lesions or +sores: they consist of large flat stains of a darkish red, more or less +soft, and sometimes ulcerations red on their deep surface, with clean +edges. + +As for the intestines, properly so called, the _duodenum_ shows the same +injuries, but most generally large ecchymosed spots. + +The _small intestine_ appears on the outside, even when it preserves its +place in the abdomen, of a reddish colour, lined with vessels distended +with blood, the signs of a general congestion of its membranes. The +examination of the mucous membrane, after it has been cut open +lengthways, shows, indeed, that this portion of the digestive tube is +the principal seat of the distemper; for, independently of this general +injection, you perceive ulcerations which have succeeded to detached +pustules or lengthy flat spots, the result of a cluster of several of +Peyer's glands, brought together by the plastic influence of +inflammation. These flat spots, or wafers, very similar to those we +observe in the typhoid fever of man, are inflamed and ulcerated in +different degrees. + +The mucous membrane of the _large intestine_ exhibits lesions depending +on the period of the disease. About the third period, the injection is +sometimes general, especially near the rectum; but in the fourth and +last period we often meet with ulcerations which are smaller in the +upper part, larger and deeper about the lower or rectal part. The +membrane of the sexual parts of the cow is strongly injected, and of a +dull red colour. + +As we have seen, the different organs of the digestive apparatus may, in +this typhus, offer to view extensive alterations perfectly consistent +with the gravity of the symptoms or the functional derangements. In two +cases in which disorders of the respiration had prevailed, and which had +been sacrificed on the eighth or tenth day of the disease, we only +observed partial injections of a very limited character, either on the +gastric membranes or on that of the intestine, and which might have +been detected in the case of common intestinal inflammation. Therefore, +in these two cases, the characteristic lesions of the typhus, if they +must be localized in the intestine, were, so to speak, absolutely +wanting. It was, we will not say exactly the same, on four other +animals, three oxen and one cow; but if, in two of them, the fourth +stomach was inflamed, if in the third the small intestine was congested, +and if, lastly, in the cow the large intestine showed ulcerations, we +could not in these lesions distinguish those of typhoid fever. + +These facts struck us with great surprise, for we were far from +suspecting them. We hoped, on opening the intestine of these animals, +which had certainly all died of the typhus, to meet assuredly in a +determined spot some well-known lesion declared beforehand. To our great +astonishment, such has not always been the case. So that our theories, +conclusive as they seemed on the identity of the ox typhus and the +typhoid fever in man, and which more than anyone else we wished to see +confirmed, must submit to observation. + +In fine, in this epizootia the intestinal lesions or sores present +different appearances. Developed to the utmost in some cases, so much so +as to exhibit ulcerations at the root of the tongue as well as in the +intestines, and to be in a manner the excess of the injuries which are +seen in typhoid fever, they are in other cases scarcely perceptible, and +sometimes entirely absent, when the animal is struck down in the third +or fourth period, that is to say, when the exanthematic or pustular +state has had time to develope itself on the digestive channels. One of +these animals seized by Mr. Tegg at the Camden Town market, was in such +a state of exhaustion that he could not be driven to the +slaughter-house, only two hundred yards distant; they were forced to +fell him on the spot midway, in order to have him conveyed to the place +of dissection. We only detected partial injections on the digestive tube +of this beast. The pulmonary emphysema which had caused this animal's +death was developed in the highest degree.--He was opened at the request +of M. Bouley, of Alfort. + +_Apparatus of Respiration._--Here, again, the typhus shows us injuries +which differ from those of typhoid fever; for if the breathing is always +more or less obstructed at the outbreak of this fever, no serious +organic change in the lungs is the consequence thereof. In the ox +typhus, on the contrary, when the pulmonary form prevails, the +derangements of the respiratory organs are remarkable. Thus, the mucous +membrane of the nostrils, from which flows a purulent and fetid mucus, +is sometimes ulcerated and excoriated. The larynx and the trachea or +windpipe, choked up with frothy mucus, show the same alterations, though +less frequently. The lungs, which are rather congested than inflamed, +are emphysematous, the air having entered and distended the cellular +tissue which unites the lobes together. + +In some cases, the lungs are so gorged with air that their lobes +constitute but a single heap, rendering them irrecognisable, so greatly +do their volume, their specific gravity, and their spongy aeriform +aspect differ from the natural state. + +_Apparatus of Circulation._--The inner sides of the heart show +ecchymosed spots, and the same is the case with the larger vessels. The +blood, diminished in its quantity and altered in its quality, is +blackish and more fluid; but in most cases it coagulates instantaneously +and in a mass, without separating into its solid and liquid parts. + +_Nervous System._--Having observed and dissected the dead bodies at the +slaughter-houses of the markets, we were not able to examine either the +brain or the spinal marrow. Besides, let us remark in this place, that +the mode of felling cattle in England would have rendered impossible +such an examination. For the animals are struck with a club, which kills +them both by cerebral concussion and by the direct alteration of the +brain; the instrument having a sharp end which perforates the skull and +injures the cerebral lobes. Nor is this all; the moment the animal is +struck down, a flexible rod is inserted into the hole made in the skull, +and driven as far as the spinal canal, so as to tear to pieces the +protuberance and the bulb, that is to say, the vital knot. This manner +of killing cattle seems to us, however, preferable to the one adopted +in France, where the animal does not sink till he has been struck +repeatedly with the club. + +But be that as it may, those authors who have examined the nervous +centres of horned cattle which had perished victims of the typhus, have +usually found the meninges, or membranes that envelope the brain, +injected, whilst the brain itself was slightly dotted over with blood. + +These anatomical lesions of the nervous centres being insufficient of +themselves to explain the death at the second period, we have +endeavoured to give the explanation of it in treating of the symptoms. + +The other organs, the spleen, the liver, the kidneys, present +alterations of a secondary interest only. + + +III. + + _Diagnosis--Prognosis--Use of the Flesh of Animals which have + Died of the Typhus--Danger of direct Absorption._ + +The typhus of the ox has such distinct and strongly marked +characteristics that it is not easily mistaken. However, to conform +ourselves to received custom, I will say some words about the principal +symptoms of some distempers affecting the ox, between which and typhus +unprofessional persons might be embarrassed, and hesitate to distinguish +them. We will transfer, however, those particulars pertaining to the +diagnosis to the part written for the special use of agriculturists, +farmers, and graziers, in order that they may readily find whatever it +may be necessary for them to know when they chance to have any sick and +tainted cattle to treat and cure. + +We have likewise a few words to say on the subject of the prognosis of +the disease, as regards its propagation and its time of lasting. +Finally, we will unfold a question of very real importance in +hygiene--we mean the use and consumption of the flesh of animals as +food, and the danger which may accrue to man and other animals from +contact with their dead bodies, or fragments of the same. + +The diseases of the ox, which we are accustomed to consider as +distinguished from typhus, are the contagious peripneumonia, the +apthous fever, and the "charbonneux" typhus; but, as we have just said, +we will mention by-and-by their chief characteristics. + +Everyone is anxious, and natural indeed is that anxiety, to know what +this epizootia will become--what will be its course; how long it will +last; whether it will extend its ravages over the whole extent of the +three kingdoms; and if, in fine, it will invade all Europe. + +To answer in a precise manner these questions would be a difficult task; +for who amongst us can assign at present any definite course to the +atmospheric variations? and yet they have a genuine influence on the +progress of the epizootia. On the other hand, the measures which have +been taken hitherto to confine the contagion to its different foci, have +unhappily proved almost ineffectual, but it may be hoped that, assisted +by experience, we shall be able to resist the evil more effectually, and +check its propagation. + +If the atmospheric conditions and the preventive measures could not +modify the spread of the distemper, we should have reason to dread a +still greater extension of the contagion; for the virulent character of +the epizootia appears to be of an exceptional intensity, and we may +perhaps compare it with the famous epizootia, of the middle of the +eighteenth century, which for ten years afflicted all Europe with its +ravages, striking down six millions of horned cattle. + +Let the reader cast an eye over the extracts borrowed from the +physicians of the principal faculties who have described this typhus, +and which we have reproduced in the first part of this book relating to +its history, and he will then be convinced that the disease is +absolutely the same as that which then raged so fiercely. And if that is +the case, we must anticipate that it will extend its ravages whilst +prolonging its duration. Already it has spread to Holland and Belgium; +Hungary and other provinces in the south-east of Germany--a fact much +less surprising--are likewise smitten with it; and now we hear the news +that France, though so vigilantly on her guard, has seen her frontiers +passed over. In spite of the _cordon sanitaire_ which she had prudently +established everywhere, some horned cattle have been seized with the +typhus at the town of Raubaix, in the north. + +Without setting ourselves up as pessimists, let us declare that we must +expect that the contagion will continue to spread. Let us make up our +minds to this, in order to take the necessary sanitary measures, and set +ourselves seriously to work by trying the preventive treatment. But, +alas! between the Government, the municipal corporations, the +agricultural societies, the cattle proprietors, and, with regret we add, +the veterinary surgeons, there has been sadly wanting, up to the present +time, that mutual understanding; that prompt and decisive action, and +those pecuniary advances which are so necessary to encounter and contend +with this great calamity. + +As for estimating with any approach to accuracy the sacrifice of +property; the pecuniary loss, which this fatal epizootic may occasion +the country, the want of exact statistics as to the number of cattle +which have already been struck down will not permit us to do it. But we +may, perhaps, already set it down approximately from 50,000 to 60,000 +head of cattle for England and Scotland, until we have obtained more +precise statistical information on this significant point of inquiry. + +That would represent, however, a very considerable capital; for if we +compute the loss of each animal at the average sum of 15_l._ only, the +sacrifice already incurred would not be less than from 750,000_l._ to +900,000_l._ This sacrifice in money might possibly have proved the be +all and the end all; and at this point we might, perhaps, have arrested +the contagion, had we all been able to act advisedly and harmoniously +together, in the name and for the interest of the public, from the first +appearance of the disease. But this calculation of, let us say, +900,000_l._, is made on the supposition that each cattle owner had been +willing to abide by his own loss; whereas, unfortunately, many of them +have striven to shift it on others, and large numbers of the sick and +tainted beasts having been sold and consumed, a proportionate sum thus +recovered by those avaricious men must be of course _deducted_ from this +estimate. Deducted, indeed! Considering the consequences on the public +health, is it not rather an aggravation than a mitigation of the loss? + +These last assertions naturally lead us to inquire whether we are not +justified in saying that the flesh of sick and tainted cattle, thus +circulated and consumed, has not had its baleful effects on the public +health. + +The butchers who sold the flesh of these sick and tainted cattle have no +doubt been careful to abstain from using it in their own families; and +the first time they speculated on the health of their fellow-citizens, +well knowing what they did, their conscience probably reproached them +with the misdemeanour. But afterwards, when no bad consequences to their +customers had been seen, their own impunity, joined to this apparent +harmlessness to their neighbours, rendered them bolder, and it became a +daily habit with them to sell this peccant offal, which poisons even the +earth by its contact. + +Moreover, the graziers themselves were in league with the butchers, and +took care to slaughter the affected animals before the wasting of their +flesh by the progress of the distemper had bereft them of their greatest +value. Their private interest prompting them thus to dispose of the +sick animals as fast as they could, the majority of the tainted beasts +were sold and eaten in the second stage or period of the typhus. + +Now, if the flesh of these diseased animals had been eaten raw, +accidents most terrible and appalling would certainly have been the +consequence, although dogs may have fed upon it without injury. But the +cooking of animal flesh at 100 degrees of heat has the property of +destroying for a time the septic germs, as the famous debates now being +held by the experimentalists who are studying the subject of spontaneous +generation tend to show. This poisonous meat, therefore, may at first +have been digested without producing immediate ill effects. + +Our medical practice, however, authorizes us to declare that, after +making every allowance for the influences of this extraordinarily hot +summer, digestive and nervous complaints of the acutest description, and +without any special cause to account for them, have been very numerous +indeed during the last two months, and beyond all proportion greater +than they usually are in London. And we cannot but feel that, if the +cholera should reach the shores of England at this critical conjuncture, +it will find organisms most ready to receive its virus. Then, indeed, if +the typhic miasma come to mix and blend with the choleraic miasma, all +living beings will have to contend with the most deleterious causes of +alterations in their health, and we may (God send it be otherwise!) +witness one of those measureless calamities which, known in former ages +as the _Black Pestilence_, decimated cattle and men indiscriminately, +and which, when we read the sorrowful accounts of it in history, make +the flesh creep with affright. + +We sincerely hope that such misfortunes may be spared us. But ought we +to abstain entirely and absolutely from consuming the flesh of cattle +smitten with typhus? It is a delicate question, but still we shall +answer it, making due allowance for every interest concerned. + +We conceive that all animals which are smitten with the early effects of +the disorder, which begin to operate at the opening of its second +period, that is to say, when the first symptoms are declared, such as +stupor, loss of appetite and shiverings, may be handed over to the +butchers. But this must only be done on the _positive understanding and +condition_ that every animal, sick or not sick, in times of epizootia, +shall pass, either in the farm, the market, or the stable, under the +examination of a competent veterinary inspector, who shall mark the +beast when fit to be sold for consumption. With this precaution, which +at present is put in practice in Belgium, every interest is cared for +and guarded--those of the public health as well as those of the cattle +owners. + +But there is another question of some importance which deserves to fix +our attention for a moment. People sometimes inquire whether the +ox-typhus can be communicated to other animals, and even to man, either +by contact, by direct absorption, or by inhaling the miasma floating in +the atmosphere. + +Experiments of great interest might be made on this subject; but we can +already assert, on the evidence of facts publicly known, that the direct +absorption of putrid matter and purulent secretions, and likewise the +mere contact with tainted flesh, when the epidermis or scarf-skin is +cracked or peeled off, or when the least open sore exists, may give +access to the disease, and produce death, both in man and other animals. +In these cases, the absorbed virus operates, not as a specific agent, +giving birth to typhus, but as a provocative septic agent, endowed with +infectious properties, which infuse into the economy a germ of virulent +and mortal disease. So long as a sound and intact outer skin stands as a +safeguard between us and absorption, we may fearlessly touch and handle +the tainted flesh of these animals. But the slightest sore or abrasion +is an open door to let in death. A young veterinary surgeon, who had a +slight wound in one of his arms, was carried off within forty-eight +hours, as was proved at a coroner's inquest, after he had dissected an +ox which had died of the typhus.[P] + +We see by this fatal example that we must be particularly careful not to +touch an ox tainted with typhus when we carry about us any open sore, +unless we take the utmost precaution in order to guard against all +direct contact or absorption. Man, as we have said and shown, breathes +with comparative impunity an atmosphere laden with the infectious miasma +of this typhus. But that which to-day is true may not be true +to-morrow; let us, therefore, be also on our guard against the too +continuous absorption of an atmosphere impregnated with these +deleterious principles. + +As for herbivorous animals in general, a similar organization must, in +their cases, predispose them to receive the contagion. Whenever we visit +the markets, we cannot help fearing to see the ox typhus communicated to +the sheep and pigs which are stationed around them. It is an +unquestionable fact that, in certain epizootias, all animals without +distinction have been smitten and struck down, and the herbivorous +animals more rapidly than any other. The habit of collecting such vast +numbers of cattle in the same market, and on the same day, though +convenient for business, appears to us injudicious, especially during +the prevalence of this scourge. + +This part of our treatise was in the printer's hands when Mr. Simonds +wrote a letter to the Privy Council which justifies all our +apprehensions. The typhus of the ox has been communicated to a number of +sheep, and we must all expect to see this cruel disease assume much +larger proportions than heretofore, since it has now obtained a second +focus for its maintenance and dissemination. + + "Veterinary Department, 23, New-street, Spring-gardens, + Sept. 25th. + + "SIR,--I beg to report that, acting on the + instructions received from you to investigate without loss + of time the statement received at your office relative to an + outbreak of the cattle plague in a remote part of the county + of Norfolk, supposed to have arisen from cattle having been + in contact with some diseased sheep, recently brought to the + premises, I have visited the district in question, and + inquired into all the circumstances of the case. + + "It appears that as far back as the 17th of August Mr. C. + Temple, farmer and merchant, of Blakeney, received on his + farm 120 lambs which he had instructed a dealer to procure + for him for feeding purposes. + + "The lambs were bought at Thetford-fair on the preceding + day, and were immediately sent by rail to Fakenham, from + which place they were driven to Blakeney, a distance of + about ten miles. On their arrival they appeared to be + fatigued to a greater extent than ordinary, which was, + however, attributed to the heat of the weather and the + exertion the animals had undergone. + + "In addition to this, the shepherd observed that several of + them seemed unwell, and he remarked to his master that they + did not appear to be a 'very healthy lot,' and that he + thought it would be better to return them to the dealer. + Within a day or two of this time the symptoms of illness + were more marked in all the original cases, and many more of + the animals had been attacked. On the 24th two of the worst + cases were removed from the field to the farm premises, and + were placed in a shed for treatment, in which afterwards a + cow was put. On the 25th two of the lambs died, and in + consequence of this, and of the large number which were now + affected, the whole were brought, on the morning of the + 27th, into the same yard where the shed previously alluded + to was situated. There is also another shed, separated from + this yard only by some old furze faggots, into which the + cows were driven night and morning for being milked. The + lambs remained in the yard till the morning of the 28th, + when having had some medicine administered to them, they + were returned to the fold and never came again near the + cows. + + "While in the yard three died, two on the 27th, and one on + the 28th, and on the following day two others died in the + field. From this time the disease went on, so that by + Friday last, the 22nd of September, the day of my visit, + forty-six had either died or been killed, and twenty-seven + were in a very precarious condition. + + "On the 7th of September, ten days after the last exposure + to the sheep, a cow gave evidence of being affected with the + cattle plague, this animal being the one which had been put + into the shed occupied by the diseased sheep on the 24th of + August. A second cow was attacked on the 11th of September, + and a third shortly afterwards, which was followed by + others; so that by the 16th all the cows, six in number, a + heifer, and a calf, were all dead. + + "My examination of the lambs showed that they were + unmistakably the subjects of the plague. The symptoms agreed + in almost every particular with those observed in cattle + affected with the malady, and the _post-mortem_ appearances + were also identical. + + "With a view to ascertain the true nature of the changes + produced in the system prior to death, I had four of the + lambs killed, and from these I took some diseased parts and + forwarded them to the Royal Veterinary College without note + or comment. These parts were examined by my colleague, Mr. + Varnell, who at once recognised the special changes of + structure which are caused by the cattle plague. + + "The whole facts of the case leave not the least doubt of + sheep being liable to the disease termed the cattle plague, + and that when affected they can easily communicate the + malady to the ox tribe; and moreover, that when so conveyed + it proves equally as destructive as when propagated from ox + to ox in the ordinary manner. + + "The case is also more important from having occurred in a + place no less than fourteen miles distant from any other + where the cattle plague exists, thus placing beyond a doubt + the fact of the malady being introduced among the cattle by + the sheep alone. + + "I regret to add that this is not a solitary case of sheep + being affected by the cattle plague. I learned that some + sheep were supposed to be similarly affected belonging to + Mr. R. J. H. Harvey, M.P., on his estate at Crown Point, + near Norwich. This place I also visited, and found a large + flock of upwards of 2000 lambs, among which the malady was + prevailing. A large number had been separated from the + diseased, and gave no evidence of the malady. Very many, + however, had died, and the disease was making rapid + progress. I also examined many of the dead, and found the + _post-mortem_ appearances to be identical with those seen in + the other cases spoken of in this report. + + "In this instance the malady was brought into the estate by + the purchase of some cattle, which afterwards died from the + disease, and which were unfortunately pastured with the + sheep at the time the disease manifested itself. + + "The whole matter is one of the greatest importance, and + which I lose no time in submitting to you for the + information of the Lords of the Council. + + "I have the honour to be, Sir, your most obedient servant, + + "JAS. B. SIMONDS." + + +IV. + + _General Considerations on the Ox-Typhus, and the + Recapitulation of the Symptoms._ + +We have seen the causes, the symptoms, and the cadaveric alterations of +the Bovine typhus, and we may therefore apply ourselves at present to +the consideration of its pathogenia and its nature. Only, the limits of +this book will not admit of a complete discussion of every point of this +important question of pathology; for if we desired to show in what +respect the typhus differs from, and in what respect it resembles, such +and such a morbid entity, febrile, infectious and contagious like it, +such a dissertation would require a whole volume for itself; we are +therefore obliged to keep within certain limits. + +Like every watchful physician who has applied himself to the study of +comparative pathology, we entertained our own preconceived opinions as +to the nature of this _Cattle Plague_. Arguing _à priori_ from what we +knew, from the laws of the pathogenia of those exanthematic diseases +which we have alluded to in a former chapter; from the identity of +variola in various animals; from the preventive treatment to which this +identity has led; believing that animals and man have each their typhoid +fever, as they have their variola or small-pox; considering with the +Ecole de Tours, typhoid fever as a variola of the intestinal mucous +membrane, and having proposed, in 1855,[Q] to adopt inoculation as a +preventive treatment, drawing an easy comparison between the typhus we +are now observing and the typhoid fever in man; hoping, we may say, +indeed, to find in this typhus the inoculative and preventive virus +which is required for our typhoid fever, all will understand with what +eager and vivid curiosity we have examined the entrails of the victims +struck down by this epizootia. For, if this typhus had been a genuine +typhoid fever, the bovine species which has already provided the +preventive virus for small-pox, would equally have afforded us the +preventive virus for typhoid fever. In this hypothesis, our proposal to +inoculate the typhoid fever, which up to this time has been tried on +horses only, and in experiments badly conducted, by pupils of the +Veterinary School of Lyons, was perhaps on the eve of being realised. +But we regret to say, we have been forced to submit to evidence, and to +acknowledge that the present infectious typhus is not the one we require +to provide us with the anti-typhoid virus. + +In the same manner as pathologists disagree as to the question, whether +the typhus and typhoid fever in man are one and the same disease, so +should we long debate, without coming to an agreement, as to that which +relates to the typhus and typhoid fever of the ox. We cannot pretend to +produce a reconciliation between these dissentient schools; all we +desire, is to sum up what observation has suggested to us, on account of +the practical and therapeutic interest belonging to the subject. + +For ourselves, the typhus and the typhoid fever of the ox are two +diseases of the same order, but nevertheless distinct; and the reasons +upon which we ground our opinion are suggested to us by the nature of +the intestinal lesions, the symptoms, and causes of these distempers. + +As we have already seen, the contagious typhus of the ox, at least that +of the present epizootia, is an infectious disease, which varies in the +intensity of the functional disorders and the cadaveric lesions to which +it gives rise. The typhoid fever, we mean the real one,--for there are +other intestinal exanthematic fevers which simulate it,--always localize +on the small intestines a pustulous exanthem, and in the typhus of the +ox, this pustulous exanthem and the ulcerations by which it is +succeeded, are frequently wanting. + +The real typhoid fever springs up in every country under the influence +of local causes, and is not in the same degree infectious and contagious +as the typhus proper. In fine, the typhoid fever smites many species of +animals--the horse, the pig, etc., without transmitting its contagion +with the same intensity. + +The contagious typhus of the ox appears to be more especially proper to +that animal; for in those latitudes where it developes itself other +animals are not affected by it. + +For these reasons, then, to which we could easily add many others, we +consider the typhus of the present epizootia a special and distinct type +of typhic diseases, and differing from the typhoid fever: it is the +highest expression of its class, and occupies the first degree in the +scale of infectious typhic diseases. Next to it we should place the +typhoid fever, which we admit is not often found in the ox. But +veterinary pathology is still less understood than human pathology, and +typhoid fever may perhaps be recognised in those diseases which the +former science has described under the names of _adynamic_ and _ataxic +fevers_. Besides, a persistent research among the veterinary memorials +and reports might possibly enable us to discover some instances in which +the real typhoid fever in the ox had been traced, apart from the +epizootic conditions. Here is an instance of it:-- + +Gellé, in vol. i. page 245 of the _Pathologie Bovine_, quotes the +following abstract which had been forwarded to him by one of his +brethren, on the dissection of an ox, which was made on the 10th of May, +1824:-- + +"_Duodenum._--Uniform redness of the mucous membrane, with thickening, +softening, and petechial spots. In the middle portion were discovered +some of Peyer's glands, small round pustules, whitish at the top, with +a reddish circumference. In some parts contiguous to these pustules lay +ulcerations somewhat extensive, which seemed to be the result of the +softening of the pustules which had preceded them. A dark pus issued +from these ulcerations. The inflammation by which they were attended was +diffused in some places, whilst in others it was circumscribed. In some +parts the intestinal mucous membrane was utterly destroyed. The +mesenteric glands were red and soft." + +Gellé adds:--"I have recorded this interesting narrative, as it may +perhaps serve hereafter to throw light on a point of doctrine." + +The intention which Gellé nurtured at the time, is, we see, now +fulfilled conformably with his object. + +The contagious typhus of the ox not being a real typhoid fever, we shall +not, consequently, be able to borrow from it the preventive virus for +that disease in man. But if these diseases differ, and if it is +difficult, in the present state of science, to assign to them such +distinct characters as to produce a perfect agreement among all medical +writers, we must, however, admit, that to designate the ox-typhus now +before us by the generic name of PLAGUE, after the Germans, who +have given it the name of RINDERPEST, would carry us too far +back. + +Let us acknowledge also, that the denomination of _contagious typhus_, +adopted by the French veterinary doctors, is not, any more than the +designation of TYPHUS FEVER, applied to it by English physicians, +totally free from objection. + +In truth, the various species of typhus whose characteristics we have +already given (see p. 73), are all of them febrile and contagious. +Whoever uses the word _typhus_, speaks of a contagious and febrile +malady, inasmuch as we cannot conceive typhus without its +accompaniments, fever and contagion. But as the prevailing +characteristic of this infectious disease is, above all, its +_contagion_, we have preferred to adopt the name of _contagious typhus_, +without, however, deceiving ourselves as to the value of the +denomination. The final elucidation has not yet been found for these +diseases; at some future day they will be methodically divided and +arranged, and each of them will then receive a special title, which will +remove from the mind that vague uncertainty which at present we regret. + +But if some faults of doctrine are open to debate, no doubt whatever can +exist in the mind as to the morbid individuality of ox-typhus, or the +general conditions of its pathogenia; and we are able to deduce from the +preceding explanation, the following conclusions as so many propositions +definitively settled:-- + +1st. The typhus of the ox is a disease essentially infectious, which is +produced by the absorption of the morbigenous miasma in the air. + +2nd. This typhic miasma is absorbed and engendered by the ox, under the +influence of a number of special deleterious causes. + +3rd. When the miasma has been absorbed and incubation produced, the +disease itself is but a supreme effort of nature--a struggle between the +vital forces and the morbid evolution of the poison, in order to guard +and defend life against the danger which threatens it. + +4th. A malady essentially general, _totius substantiæ_, it directs its +action, in different degrees, over the whole structure, but chiefly on +the nervous centres, on the organs of respiration, and on the digestive +apparatus. + +5th. Its progress is regular; to the latest period of incubation it +succeeds that of the general poisoning of the blood--that of the pyrexia +of general fever--which for a time stops up all the secretions. Then, +the morbid flux is localized according to particular predispositions: +either on the nervous centres, when the animal is struck down at the +outbreak; or on the lungs, when the respiratory derangements become the +leading symptoms; or on the digestive channels, when the train of +typhoid phenomena is observable. + +6th. The period of acute inflammation, which had dried up the sources of +secretion, gives place to that of the depurative and critical +exhalations or secretions; from every mucous membrane, from every +outlet, there issues a mucous discharge, which at first is thin and +clear, but afterwards becomes thick and purulent, and endowed with the +most infectious properties. The intestinal mucous membrane, smitten with +a particular lesion, becomes the seat of a flux extremely copious and +intolerably fetid. Gases, and occasionally purulent deposits, are +developed in the cellular tissue beneath the skin. + +7th. The organism or physical frame, disturbed in the very centres of +life, undergoes a general transformation, a kind of organic +decomposition beforehand, and all the symptoms of reaction are followed +by a period of wasting atony and adynamia, which usher in dissolution or +life's extinction. + +8th. Finally, throughout the whole course of the distemper, one special +functional derangement--_stupor_--has been witnessed as the predominant +symptom, the nervous system being in a manner annihilated in its +functions in consequence of the general infection. + +Such are, in a brief outline, the principal symptoms of this typhus, +which, when once engrafted on the economy, pursues its fatal march, and +no treatment can then arrest its evolution. As in small-pox, so in +typhoid fever and in most general disorders, Nature for a time must be +allowed to exercise her new functions, which succeed each other in due +course, and which the physician must not stop; for if he did, he would +accelerate death; but he must watch with a vigilant eye, in order to +assist the vital powers. + +The medical man, satisfied with these facts, will therefore abandon the +chimerical hope of finding a specific remedy for such a disease. The +virus once absorbed, the frame will endure, and fatally endure, all the +morbid phenomena which must produce and succeed each other. _Against +such a poison no other antidote exists than the poison itself._ And this +will be easily understood. What necessity have we for a specific remedy +to resist a distemper, which carries within itself its preventive +treatment? If it germinates and is propagated, let us not accuse Nature +and render her responsible; our own blindness, the lack of a community +of interests among the people, our social institutions, the still +imperfect state of the exact sciences, &c., amply explain how it is +that we have not yet employed the effectual means we possess, not of +curing it, but preventing it. If we could have our choice between +prevention and cure, should we not naturally take the former? + +Indeed, the sources, the causes which generate the typhic miasma, are +thoroughly well known to us, and these we can avoid. The developed +miasms hang suspended in the air; we may, perhaps, one day destroy them, +if not in the outer atmosphere, at least in the stalls and sheds where +the animals inhale and absorb them. In fine, if we are powerless to +arrest the fell disease when its periods revolve, we may hope at some +future time to act with greater efficiency upon it during its period of +incubation. + +On the other hand, if this formidable disease cannot be stopped in its +progress, does it follow that we should not treat it at all? Certainly +not! Far be such a heresy from our thoughts. What would be the +consequence, if we left to their fate the sufferers from the small-pox, +from typhoid fever, and from typhus itself, instead of watching over +them with the utmost solicitude? If the physician, the enlightened +interpreter of morbid phenomena, did not direct them with a bold and +fearless hand, but abandoned Nature to her helpless course, why, +necessarily, every patient would die, whereas a large number are now +saved. + +That which is true in the case of man, is likewise true in the case of +animals: we are bound to treat them when they are ill. If to-day we +think it more expeditious and more profitable to exterminate them, we +certainly neglect our duty. We are the sovereign masters of animals; +they are the companions of our toils and pleasures, their lives must be +given to preserve our own; but on their well-being and their happiness +our own well-being and happiness also depend. They will return to us the +sufferings and diseases of which they die a hundred times over. Like +ourselves, they die of consumptive, tubercular, cancerous, eruptive, +typhoid, and parasitical diseases. And who can tell whether they have +not communicated these disorders to man, who was, perhaps, originally +exempt from them; and whether they do not continually communicate them +to him? + +What noble pages might be written on the close connexion which exists +between all organized beings, both physically and morally! Let us love +these animals, let us treat them with kindness, and all our other +qualities will be raised by so doing. + +But as a man must belong to the time he lives in, we will take up for a +moment with the doctrines of the economists; we will tolerate the +extermination of diseased animals, as a painful necessity. Our duty is +to seek in the study of the diseases of animals _and in their cure_, the +cure of the disorders which afflict the human species. We shall, +therefore, now proceed to consider the subject of the treatment of +horned cattle, both as relates to preventive and curative medication. + +FOOTNOTES: + +[O] Mr. Simonds has for three months had under his observation a cow +which has lived with impunity among animals sick and dying of the +typhus. And a young calf did not contract the disease for more than +three weeks. + +[P] Another instance of the fatal effects of the terrible disease now +ravaging our flocks and herds of cattle, and resulting in the death of a +veterinary surgeon, has just occurred in the town of Sudbury, Suffolk. + +Last week the epidemic made its appearance in the stock-yard of Mr. +Ruffell, farmer, Melford, and the cases were attended by Mr. Robert John +Plumbly, veterinary surgeon, Sudbury. On Thursday a cow, which was +evidently suffering from the disease, was brought out and shot by Mr. +Plumbly, who afterwards made a partial _post-mortem_ examination of the +carcase. In doing so with a small scalpel his shirt-sleeves became +saturated with blood, &c. from the animal. He returned home, and the +same day was attacked with sickness and acute pains in the head and +chest, accompanied with a soreness in the bones generally. On the +following day he appeared somewhat better, and was able to attend to his +duties, but became worse towards evening, and was confined to his house +on the following day. He considered that he was merely suffering from +the effects of a severe cold, and did not call in medical assistance +till Saturday night. He slept well that night, and seemed somewhat +better on Sunday morning. About two o'clock in the afternoon he got out +of his bed to have it made, when he appeared comparatively strong and in +good spirits; but almost immediately afterwards he was taken in what +seemed to be a fit, and expired in a few minutes, before the surgeon, +who only lived next door, could come to his assistance. It was thought +that death had resulted from apoplexy, and a medical certificate to that +effect was given. Rumours, however, soon becoming current that Mr. +Plumbly's death was caused by the cattle plague, the borough coroner (R. +Ransom, Esq.) directed a _post-mortem_ examination to be made. But, by +this time, so rapid was the spread of the virus through the system that +the body appeared perfectly plague-stricken, and by Tuesday morning, +when the surgeons arrived to examine it, and it was taken out of the +coffin, the corpse scarcely retained the semblance of a human being, the +head and trunk being much swollen and black in colour, the features +quite undistinguishable, and all the flesh converted into a putrid +jelly-like mass. The tissues were completely disintegrated, so that it +was utterly impossible to make any examination. + +An inquest was held on Tuesday afternoon, at the court room, Town Hall, +before the coroner, R. Ransom, Esq., and a jury; Mr. Joseph Barker, +chemist, being chosen foreman. The mayor (S. Higgs, Esq.) and other +gentlemen were present during the whole of the inquiry, which lasted +four hours. + +The jury went and viewed the body, which lay in an outhouse, but were so +overcome with the fearful spectacle that they were permitted by the +coroner to retire to partake of stimulants before they could further +proceed with the inquiry. + +The first witness called was Mr. William Brown, veterinary surgeon, and +partner with the deceased, who deposed to having gone with him to Mr. +Ruffell's farm at Long Melford, on Thursday last, to examine several +cows down with the cattle plague. One was brought out and shot by the +deceased, who proceeded to examine the intestines and viscera, which did +not present the appearances usually observable in advanced stages of the +disease, there being but slight ulceration of the coats of the stomach +and bowels. The lungs were not examined, as the deceased had only a +small scalpel with him. In making incisions in the body the +shirt-sleeves of the deceased became covered with blood, but he did not +prick or cut himself. + +Henrietta Dansie, nurse, was examined, and said that deceased had been +suffering from boils on his right arm, one of which she had poulticed on +Wednesday, the day before he had examined the diseased animal. He +removed the poultice himself, but declined to put on a plaster as the +place was a small one, although not healed. He changed his linen on his +return from Melford; but the same afternoon he was taken with sickness +and vomiting, and complained of acute pains in his head and bones. On +Sunday afternoon, shortly before he died, he wished to have his bed +made, and got out and stood whilst it was being done. He then complained +of faintness, and got into bed again, and witness to revive him washed +his face and hands; in doing so she observed that the nails of one of +the hands which had lain in the bed were turning black. She was about to +give him some pills when she noticed a sudden change come over him; and +thinking he was going to faint or have a fit, she rang for assistance +and went herself for the doctor, who, being from home, another surgeon +residing next door was called in, but by this time the unfortunate +gentleman was quite dead. + +Mr. Maurice Mason, surgeon, said he was called in to see the deceased +the night before he died, and visited him again on Sunday morning, and +ordered him a lotion and leeches for his head and effervescing drinks +(the leeches were not applied). From the appearance of the body and the +evidence which had been adduced, witness was of opinion that the death +of the deceased was caused by the absorption of poisonous virus from the +dead beast. + +Mr. W. B. Smith, surgeon, gave similar evidence, and added that the +tissues of the body were so disintegrated that it would have been +utterly impossible to have made a _post-mortem_ examination. + +After half an hour's consultation the jury returned a verdict, "that +deceased died from the effects of the absorption of virus or poison into +his system upon the occasion of his making a _post-mortem_ examination +of a cow which had died from a certain disease called the cattle +plague." + +The sad occurrence has caused much sensation in the town, the deceased, +who was only 23 years of age, being well known and much respected. + + +[Q] "Appel à des Expériences dans le but d'établir le Traitement +Préservatif de la Fièvre Typhoide et des Maladies infectieuses +inrécidivables, par l'inoculation de leurs produits morbides." Memoire +lu à l'Institut, le 8 Octobre, 1855. Inséré dans la Gazette Hebdomadaire +de Médecine. Paris. + + + + +CHAPTER IV. + +_Treatment and Cure of the Ox-Typhus._ + + +In now addressing ourselves to the treatment, and, as far as human +agency can effect it, to the cure, of this insidious distemper, we +cannot conceal from ourselves, that this is the most difficult, the most +delicate, and, at the same time, the most important division of our +work; for it is to this part, above all, that attention will be +directed. This portion of our task, therefore, will prove especially +arduous; and nothing can give a better notion of the difficulties we +shall have to encounter than the many fruitless attempts which, for +several months past, have been made to overcome them by many ardent +inquirers, stimulated by the best possible intentions. + +This, then, is the moment--if we may be allowed the metaphor--to take +the bull by the horns; and we do so without hesitation. If, like so many +others, we are baffled and overcome in this unequal struggle--if our +strength is not on a level with our desires--we trust we shall be +pardoned. + +Several paths leading to the same end may be followed in this exposition +of the treatment of ox-typhus. After mature reflection, we shall adopt +the one, which will allow us to take the disease at its birth, _ab ovo_; +to study it in all its phases, in its first and second causes, and then +in the successive periods of its development. + +In this manner, we shall be able to give an account of each fact of real +importance mentioned in the foregoing pages, and to comprise within the +treatment whatever is connected either directly or indirectly with the +disease. + +Thus we will relate in so many separate articles,-- + +1st. The means and measures to be employed to meet and resist the first +local causes which may generate the typhus, then the secondary causes +which serve to propagate it. + +2nd. The means of preventing the spread of the disease to animals still +in good health. + +3rd. The means of treating it at its different periods, from the period +of incubation to that of its decline. + +4th. Finally, we shall insert the laws and sanitary regulations which +have been published in England relative to this disease. + +As will be seen, by adopting this method, the whole matter will be +considered consecutively and in regular order; and the reader will +understand that when such a phase of the malady is developed it is +because the preceding one, which is the cause of it, has not been +effectually contended with. + + +I. + + _Means and Measures to be employed to resist the Causes of + the Contagious Typhus of the Bovine Species._ + +We have shown fully and explicitly in what countries of the globe, and +in what particular conditions, the typhus is generated among oxen. We +know that this dire disease has its focus on the banks of great rivers +or lakes, which are periodically overflowed, and on which is deposited a +slime teeming with organic matter; in marshy plains, where the same +natural impurities are fostered; and that these first hotbeds of the +evil are found in China, in India, in America, in Africa, as well as on +the shores of the Black Sea. A spirit of observation which delights in +measuring the phenomena of nature with the contracted compass of its own +short views and conceptions, could alone have imagined that the +ox-typhus was only to be found originally in the steppes of Hungary and +Russia, and that the bovine species of those countries, thanks to a +special organization, was alone capable of generating the typhus. + +Since we know, then, in what conditions this disease is developed, and +especially in what manner it is propagated in Europe, it is not +impossible now, when nations are united by the means of quick and easy +communication, by commercial treaties, and by the mutual relations of +science, to examine what measures might be taken to modify and control +these conditions. A commission formed for this purpose, a scientific +congress, would be able to make on the spot a study of all the +circumstances which favour the development of typhus, and the result of +their reports would enlighten the peoples as to the causes which produce +it and from which they are first to suffer. They would be recommended to +choose as pastures the healthiest places, to withdraw their cattle at +certain seasons from those plots of ground which are baleful to them; +new systems of agriculture would be planned and tried, &c. These +questions being carefully examined, might lead to important results; nor +can we understand how, in the age in which we live, the same +indifference and apathy as prevailed in the past should be maintained in +presence of the positive and permanent causes of this infectious +disease, whose contagion, as we now see by many proofs, may extend at +once to so large a portion of Europe. There is now something to be done +in this matter; it is the duty of the governments to deal with it +effectually, and to take serious measures to destroy the evil radically, +if radically it can be destroyed, and, if not, to alleviate its +pernicious effects as much as possible. + +Moreover, many breeders of cattle have not waited until now to guard +against some of the first causes of the typhus: already they give the +animals rock salt, ferruginous and arsenical preparations, but all this +is done without method, and according to each man's will and pleasure. +It would, therefore, be necessary to institute regulations, and to see +them carried out and practised under the superintendence of public +functionaries, armed with sufficient power and authority. + +These measures having been taken, others no less indispensable ought to +follow. They should determine for the herds of cattle intended for +exportation, the ways and channels they must travel by to go to any +central part or to any railway station; and there the inspectors on duty +should mark every animal that passes out of the district he is leaving. +Heavy penalties should be inflicted on all who might infringe these +rules. + +These precautions would contribute in part to arrest the propagation of +the complaint; but there is another measure more radical and effectual, +which should be taken in order to prevent its extension--we mean +inoculation, which has met with complete success in some of the +governments of Russia. + +Thus we see, there are powerful means of withstanding the production of +the disease in its focus, or generative bed, and likewise its extension +among the herds of neighbouring countries; and these latter might render +them in some sort obligatory, by refusing most rigidly to admit to their +markets, as in Italy has sometimes been done, every head of cattle which +was not marked as inoculated or which was not furnished with a permit of +health. + +It is easy to conceive that those countries wherein the ox-typhus has +its birth, and for which the breeding of cattle and their exportation +are a great source of wealth, would soon feel that they are more +interested than any other in stifling the contagion in its focus, and in +affording to those countries that receive their herds, every security +and guarantee which they have a right to expect. Interest in this case +coming to the help of common sense, very satisfactory results would in +course of time be obtained. + +Moreover, we are conscious that we are here dealing with very +complicated questions; for, though in a book they may seem simple and +easy, their application is a matter of extreme difficulty. We know too +well that these preventive measures for protecting animals will meet +with many obstacles, and only be adopted at last with tardy reluctance, +since man himself continues in some respect indifferent to the causes +which spread about the fearful epidemics to which he falls a victim in +consequence of his neglect. + +In truth, it is well known that the cholera of the present day--that +much more serious _plague_--had its origin on the banks of the Red Sea, +amidst the infectious miasmata developed near Mecca, where thousands of +pilgrims who had died of fatigue and privation, and hundreds of +thousands of sheep butchered and religiously offered up in sacrifice, +have, beneath a torrid heat, generated the choleraic miasma, which +formerly was supposed to be produced exclusively on the banks of the +Ganges. This fact duly ascertained and proved, we might suppose that the +governments of the different nations among which the cholera is about to +extend its ravages, were indignant and had complained at thus being +smitten with a scourge, due to the careless ignorance and sordid avidity +of some official of the Turkish Government. But we should be mistaken. + +No! every one hoped at first that he, at least, would be spared by the +contagion, and the authorities did nothing to resist the evil but adopt +the old course of _quarantine_--a remedy more illusory now than ever, +since the nations are in constant communication, either in their own +persons or by the exchange of their commodities; and consequently, the +epidemic is pursuing its invading course from week to week. + +That which is being done for the cholera gives us a scale by which we +may estimate the efforts which will be made to arrest the generation and +the contagion of the cattle typhus.[R] + +We are certainly bound to resist the introduction of horned cattle +tainted with typhus; but in the conditions amidst which they live, some +of them may bear the seeds of the distemper, even whilst they appear in +perfect health, and therefore able to endure the fatigue of a long +journey. + +Now, in order to avoid exciting the incubation of the typhus during +their transit either to Finland, Holland, France, or England, it must +never be forgotten that these animals are gifted with a nervous +sensibility of wonderful acuteness, joined to the weakest vital +resistance. Care must be taken to husband their strength, to give them a +choice distribution of food easy of assimilation; barley-meal, or other +grains, must be mixed up with their drink; they must be protected from +the changes of weather; they must have room enough and air enough in the +locomotive stalls on the railway trains and on board ship. + +We pass over in silence the hygienic measures to be taken in order to +keep these vehicles of transit in a proper sanitary state: the sanitary +police regulations inserted further on will make them sufficiently +known. + +All these measures having been taken to meet and withstand distant +causes and dangers, let us now direct our attention to those local +causes which strike our eyes, and which likewise have their share of +influence in propagating the disease. Thus, whenever an inclement season +comes to deprive the herbivorous animals of sufficient pasture, or to +deteriorate its natural qualities, we are bound to remedy this change, +and to increase the cares we devote to them; for these frail and +helpless creatures, immediately feel and suffer from the effects of a +sustenance less than usually restorative. Under such circumstances, we +must make exceptional sacrifices; when they return from feeding on the +grass, we should give them some additional fodder, or roots of a +generous quality. We must imitate the regimen used in the country of the +steppes, by adding to their forage a solution of marine salt, or a +solution of sulphate of iron. Day by day we must give to the weakest and +least fed cattle, a ration consisting of bruised oats, pounded juniper +berries, gentian, sulphate of iron, and carbonate of soda. + +For, if we neglect to take those measures which are required to prevent +among herbivorous animals the development of those ordinary epizootias, +which every year are generated on our own soil, they will certainly +afford a favourable seat to the typhic miasma transmitted by foreign +animals, or exceptionally generated by themselves. These cares and +attentions must be greatly increased, when the foreign epizootia, has +spread itself, as in the present instance, among our flocks and herds. +Then, indeed, we must be careful not to load these creatures with +pampering food for the purpose of fattening them. For it may be +profitable, and the breeder may plume himself, on having produced an +adipose monstrosity to such a degree as to bury, for instance, a pig's +head in the fleshy exuberance of his thorax; but such a derogation from +the laws of nature borders closely on disease, and assuredly such an +unnatural accumulation, predisposes the glutted animals to epizootic +diseases in general. + +The water given them to drink must be attended to with particular +solicitude. It should never be drawn up from ponds or stagnant rivers. +The animals kept in the pasture grounds should always find at their +disposal, in receptacles intended for their use, a supply of pure fresh +water. + +After these precautions with respect to their food and sustenance, +attention must next be directed to the hygienic conditions required by +the animal. Every morning he should be cleaned, washed, brushed, and +dried; what is every day done for the horse must now be done for the ox. +These unusual cares will be most salutary to him, and greatly increase +his vital resistance. + +The animal thus protected in his food and particular necessities, +attention must next be directed to the stalls and sheds. Over-crowding +must be carefully avoided; the proper cube of air for breathing must be +measured out for each head of cattle; every day the latter must be +carried out into the open air; the floor of the stall or shed must first +be thoroughly cleansed and washed out, after which it must be sprinkled +with a solution of chloride of lime. If the stall is not well aired, a +little straw should be burned on the ground, to improve the atmosphere, +or else branches of resinous trees, or juniper berries may be used. In +some cases aromatic fumigations of sage, rosemary, or mint, boiled in +water, are employed, the balsamic vapours which arise therefrom being at +once tonic and purifying. During the night a tub, containing pitch and +tar, should be left in the stall, or a large piece of camphor should be +suspended from the ceiling. Vinegar may be spilt on a piece of red-hot +iron, or powder of sulphur may be burned into sulphuric gas and diffuse +its vapours through the stall or shed. This excellent parasiticide may +perhaps be equally endowed with anti-typhic properties. + +Finally, when this fatal epizootia is ravaging the country, every farmer +and agriculturist must carefully abstain from mixing with his herds any +cattle which have been bought either at fairs or markets; he must take +care, conformably with the directions issued by the Privy Council, (to +which we refer the reader for more ample details,) to avoid all contact +both direct and indirect with horned cattle tainted with the typhus, as +he might himself become an instrument of the contagion.--Let him never +forget that to take as the guide for his actions in these times of +calamity his private and personal interest, is the greatest crime a man +can commit. Let him strive, therefore, to assist the authorities in the +measures which they have taken for the interest of all. + + +II. + +Now that we have examined the measures which prudence directs us to take +to defend ourselves against the causes which produce and propagate +typhus, let us think of the means of preventing it, when the contagion +threatens to diffuse itself over a whole kingdom, as at present it is +doing in England. + +When, on the 19th of last June, it was believed that the typhus or +Cattle Plague, as they continue to call it, had effected its invasion in +England, the Government, informed by professional men of the serious +danger to which the interests of the country would be exposed, if the +disease should spread, might have considered this distemper not as a +question of private interest, but as one of public and national concern. +It might at the outset have given to this epizootia all the significancy +of a public calamity, have looked upon it as the invasion of an enemy +threatening to destroy its territory, and have employed every possible +means to stifle it at its birth. + +We well know that the English Government, derived as it is rather from +political than from religious and social changes, is at once +monarchical, aristocratic, and partially democratic, and for that reason +embarrassed in its working by so many wheels. Its authority is scattered +and divided, whilst the respect ascribed to the prerogatives of each +distinct public power is the safeguard of the State. In the absence of +both Houses during the recess, it could take no resolution as to ways +and means; for the difficulties on this unhappy occasion, we cannot too +often repeat it, are reduced to a question of money. Deprived of the +requisite authority, it was unable to do more than exhume the old laws +on the matter and ordain new ones. And yet, the impotence of the +Government was not perhaps so great as is imagined; for whilst it +suffered the typhus almost unmolested to devastate the country, it very +justly, and in the name of the public interest, took vigorous and +effectual measures to stamp out another epidemic--the rash and insane +conspiracy of the Fenians. It stood still and would not authorize +domiciliary visits in stables and stalls, nor the seizure of sick +animals, but it did not falter a moment at the domiciliary visits and +incarceration of insurgent citizens meditating mischief, so that in +this instance, the privilege of immunity has been given to the brute +creation. Everybody, both in England and out of England, admires their +vigour and despatch in stifling the insurrection in its bud. But why not +act with equal promptitude in the case of an epizootia? + +Arming itself, in this manner, in the public interest, and with +sufficient power, the Government might have appointed an executive +commission, with the Lord Mayor as president. Such a commission would +have applied itself at once to the consideration and studious +examination of the subject in all its bearings, and would have proposed +prompt and energetic measures, which the Government, with equal +despatch, would have confirmed by giving to them the authority of law, +as they have since tardily done. A fund, which, for the wealth of +England, would not have been considerable, 250,000_l._--the cost of a +few Armstrong guns--might have been placed at the disposal of this +Board, to enable its directors to meet and provide for, without delay, +every just claim and want arising from the scourge. + +An auxiliary commission, exclusively medical, and consisting of medical +and veterinary doctors, might have been formed conjointly with the +former, and every preventive measure, considered by them as necessary to +stamp out the complaint at the outbreak, after it had been proposed by +the medical board, and submitted to the executive commission, and by +them to the Home Secretary, might have been acted upon by law within +twenty-four hours. + +Taken unawares, and the mode of treating the sick animals not being +known at first, they would have been reduced to the cruel necessity of +exterminating at once all tainted cattle, as well as those belonging to +tainted herds, but not without compensating the owners of those +cattle.[S] + +They would have sent two physicians to Russia and Hungary, to observe +and study the preventive and curative medication, especially their mode +of inoculation, and thanks to the rapid locomotion of these times, +twenty days would have been sufficient for this foreign exploration. +The physicians constituting the medical board should have been +authorized to seize any beast tainted with the typhus; a company should +have been charged to collect and keep ready for the public service, at +the four quarters of London, an ample retinue of horses, closed +carriages, and working men, to convey at all hours of the day and night +the carcases of the slaughtered animals to the respective spots, where +long and deep trenches had been dug to receive them. Each carcase before +burial to have been well sprinkled with chloride of lime. + +By taking this course, every one's interest would have been respected, +as much as can be desired when a great calamity threatens a country; +besides, in doing so, the present ministers would but have followed the +example of the Government (with regard to compensation), during the +epizootia of the eighteenth century. The proprietors who had thus +received, not the full and absolute price, but a sum sufficiently +remunerative for their sacrificed cattle, would have assisted the +authorities, and thereby would have served the common interest, because +their sick cattle, perishing every hour within their stalls and sheds, +were no longer a real source of embarrassment and ruin. They would not +have been obliged to drive them to market to get what they could out of +them and disencumber themselves. The most active cause of the contagion +would by this means have been prevented. + +This allowance having been made for the most pressing dangers, attention +should next have been directed to a matter no less important--we mean +the treatment and cure of this distemper; for we will never admit that +England can have fallen back a century, and that whilst those +enlightened men--Malcolm Flemming and Layard--proposed and tried to cure +and prevent ox-typhus in 1757, we, in 1865, shall have been reduced to +the horrible alternative, the repugnant barbarity, of the general and +indiscriminate extermination of the tainted cattle. + +Whilst, therefore, the treatment of the typhus would have been studied +on the spot, and the most urgent measures would have been taken to +withstand the propagation of the evil, they would have established, a +few miles from London and on the northern side, in the direction of the +great cattle market, a number of hospitals or sanitariums, and, as far +as possible, within a park. These hospitals, constructed of wood, +containing, besides stables and sheds, a slaughter-house, a +dwelling-house for the staff of employés, a laboratory stocked with all +the physical and chemical instruments required, &c., would in two or +three weeks have been sufficiently prepared to receive a certain number +of cattle. + +Provided with these advantages and opportunities, a permanent stage of +operation would have been raised on which trials and experiments might +have been made with every chance of fruitful results. In these +sanitariums, for instance, the most practical physicians and +veterinarians might have entered upon a systematic course of treatment, +dividing the bovine patients into classes, according to their periods of +disease, their age, &c.; and trying some particular mode of treatment, +some remedy considered as effectual, alternately, upon each of these +classes of tainted cattle. These experiments, having been made under +circumstances so favourable, would have enabled the faculty to +establish a medical basis, which, if not infallible, would have been +relatively efficacious, and might have saved a large number of the +infected animals. + +Whilst thus fixing their attention on the cure of the sick animals, +these experimentalists would have carefully studied and practised the +preventive treatment by inoculation, availing themselves both of +Layard's hints and recommendations and of the practical knowledge +acquired by the medical expedition to the steppes, which would by that +time have returned from their mission. They would have selected animals +smitten with the genuine typhus, of the typhoid and intestinal form, in +_the third period_, whilst the depurative and critical secretions are +running from the mucous membranes; they would have gathered the virus +from its springs of infection or from its purulent subcutaneous deposits +or from the serum of the blood. + +On the other hand, they might have chosen four heifers, of good +constitutions and healthy, and these they might have prepared, according +to Layard's advice, for inoculation, by a special treatment, and by +hygienic and medical cares. On some of these the inoculation would have +been made near the tail, according to the subcutaneous process, with a +lancet charged with typhic virus; on others, a crucial incision, or +cross-cut, would have been made on the crupper. But, to speak truth, we +cannot do better than Layard, whose ingenious treatment, with all due +deference to a certain veterinarian of our day, deserves a very +different epithet than that of being amusing.[T] Layard says:-- + + "That nothing may be omitted which in any shape can + contribute to the success of inoculation, due attention + should be paid to the constitution and state of the beast, + no less in this practice on the cattle than on the human + species. Undoubtedly the young, healthy, and strong bid + fairer for a good issue than the old, sickly, and feeble; + each of these different constitutions demand a particular + treatment, even in the method of preparation; and however + trifling it may seem to many--the urging a necessity of + preparation--I will venture to affirm that I have seen + excellent effects arising from a rational preparation, and + fatal events from want of preparation. I have likewise been + witness of unfavourable turns, merely from an injudicious + preparation. + + "The beasts which are sanguine require moderate bleeding; + those that have but a small share of blood must have none + drawn. The strong must, besides moderate bleeding and + purging, be kept on light diet and their body kept open. + Thus, scalded bran, mixed with their hay and chaff; will + cool them. The weakly, and such as are inclined to scour, + must be kept on dry fodder, and have peas and beans given + them to strengthen them. A mess of malt, or a quart of warm + ale, with a few spices, will be very suitable for them. + + "Whatever diseases the cattle be affected with, if time will + permit, they are first to be removed. + + "The cattle to be inoculated are first to be well washed, + rubbed dry, and then curried, to remove all the filth from + the hair and skin. Then they are to be placed in a spacious + barn or stable, where the air is temperate and no cold can + come to them. There they are to be prepared according to the + direction already given, foddered with good sweet hay, and + watered with clear spring water; and if the distemper be not + near they may be turned out into the air, near the barn or + stable, and may stay there a few hours in the middle of the + day. + + "When it appears that the cattle are in perfect health, free + from any infection or other disease, brisk and lively, + neither costive nor scouring, and chewing their cud, then + the operation may be safely undertaken, and henceforth they + must be confined to the barn. + + "Since there is observed to follow the greatest flow of the + contagious and putrid particles separated from the blood, + wherever the infectious matter makes an impression at first, + particular care must be taken not to inoculate near such + vital parts as the heart and lungs, nor near the womb, if a + cow with calf be inoculated; for, though rowels are properly + applied in the dewlaps, to draw off the pestilential humour + from the breast, and in other cases beasts are frequently + rowelled in the flanks,--yet in this operation, as matter is + inserted by these channels into the neighbouring vessels, + those vital parts, or the womb, might become the chief seat + of the disease, and the event prove fatal. + + "To prevent such accidents, human beings have been + inoculated on the arms and legs, and now-a-days the arms are + found sufficient. I would recommend that the cattle should + be inoculated about the middle of the shoulders or buttocks, + on both sides, to have the benefit of two drains. The skin + is to be cut lengthways two inches, deep enough for the + blood to start, but not to bleed much. In this incision is + to be put a dossil or pledget of tow, dipped in the matter + of a boil full ripe, opened in the back of a young calf + recovering from the distemper. It may not be amiss to stitch + up the wound, to keep the tow in, and let it remain + forty-eight hours. Then the stitches are to be cut, the tow + taken out, and the wound dressed with yellow basilicon + ointment, or one made with turpentine and yolk of egg, + spread on pledgets of tow. These dressings are to be + continued during the whole illness, and till after the + recovery of the beast, to promote the discharge; and then + the wound may be healed with the cerate of lapis + calaminaris, or any other. + + "On the third day after inoculation, the discolouring of the + wound, whose lips appear grey and swollen, will be a sign + that the inoculation has succeeded; but the beasts, as + Professor Swenke informs us, did not fall ill till the sixth + day, which answers exactly to the observations daily made in + the inoculating of children. Yet the Professor adds that on + the third day a costiveness came on, which was removed by + giving each calf three ounces of Epsom salts. + + "No sooner do the symptoms of heaviness and stupidity appear + than the beasts must have a light covering thrown over them, + and at night fastened loosely. They must be rubbed morning + and evening, and curried, till the boils begin to rise; warm + hay-water and vinegar-whey must be given plentifully. Should + the beasts require more nourishment, dry meat, such as hay, + with a little bran, may be offered. I should be very + cautious in giving milk-pottage, even after the boils and + pimples had all come out, for fear of bringing on a + scouring. However, this caution is proper, that whenever + milk-pottage be given the vinegar-whey is to be omitted for + obvious reasons. In cases of accident, the same attention is + to be observed in the disease by inoculation as in the + natural way, and the medicines recommended are the same I + would use; but by inoculation there seldom is a call for + any, so favourably does the distemper proceed through its + several stages. + + "The crisis being over, it will be proper to purge the + cattle, to air them by degrees, and to have the same regard + in the management of them as is laid down in the chapter on + the method of cure." + +The typhic virus is so highly infectious and poisonous that the first +animals inoculated would have all died; it would have been necessary to +inoculate successively a number of animals with the virus derived from +the first inoculation, and transmitted from an inoculated animal to a +healthy one, by which means they would have acquired a virus of the +first, second, third generation, and so on. These inoculations having +always been made on four animals at a time; on two of them, the disease +would have been left to take its own course, in order that the +experimentalists might watch its progress and development, and the two +others would have supplied the virus for inoculation. + +At the third or fourth generation, the virus, modified and attenuated in +its infectious principles, would no longer have been mortal in its +effects, as experience has proved in Russia. Then the inoculated +animals, placed under the control of hygienic cares and a few purgative +and tonic medications, would have passed from convalescence to health. +The virus thus attenuated would have supplied the means of a practical +inoculation on a large scale to all healthy animals. + +Proceeding thus, they would, moreover, but have followed the method +adopted in those times of epidemic and epizootia when the small-pox is +raging. On those occasions, we subject our sick patients to vaccination +or revaccination; we inoculate the variola in our sheep threatened with +the contagion; we pursue the same course in cases of epizootia, of +peripneumonia. And truly, that which it is reasonable to do in one case +may be generalized and applied to a greater number. + +The experiment we have suggested might, perhaps, have been long and +difficult, nay, even costly, but we should have established, after a +certain time, the rational method of this preventive treatment, and have +distributed the same throughout the country. Veterinarians would have +formed in particular districts their centre of operation, in which the +preventive virus might have been produced, and they might have gone from +farm-house to farm-house to inoculate all the cattle within them. + +From these facts and observations made by the physicians, precious +documents would have been derived; and if, contrary to all expectation, +success had not justified every hope, we should have bequeathed to +future generations facts and experiences which would have been of the +most useful character to them and full of instruction. Thus it is that +science advances and progress is accomplished. + +If all that we have just indicated as a realizable matter had been done, +in effect, England would have afforded in this, as she has so often done +in other cases, a noble example to be followed, and would have acquired +a new title to the admiration of other nations. + +But, unfortunately it has not been so: silence has succeeded to +eloquence at Guildhall, and the meetings at the Mansion-house have +flickered away. That which was held on the 27th of September, seems +likely to be the last of them.[U] + +The subscriptions which, in spite of all the praiseworthy efforts and +earnestness of the Lord Mayor, did not reach 2000_l._, were returned to +the subscribers, so that all the attempts which have been made to +centralize the direction to be given to the various measures have proved +abortive. The plan of forming sanitariums, as well as that of +compensating the owners of cattle, have both fallen to the ground. + +What can we think of such a state of things when we see the ox-typhus +extending its ravages to sheep, and have to fear that the disease will +spread to other animal species? What serious reflections it creates in +our minds, and what awful consequences we might deduce therefrom! But +what would be the use of them? + +Let us add, however, that France, save on the recognised principle of +indemnification, and a more speedy extermination of her tainted cattle, +has shown the same deficiency as to the means of treatment as England; +whilst we have the consolation of attributing this impotence on the part +of this country to the fact that the outbreak of the epizootia has +occurred during the Parliamentary recess. + +It is, therefore, to institutions rather than to individuals that we +must ascribe the impossibility of conquering the difficulties which have +been met, and which at any other time might not have obstructed the +course of things. Far be it from us therefore to accuse of indifference +a great people renowned for their zealous promotion of public interests, +for their charity and inexhaustible philanthropy, whose innumerable +asylums have been opened to every misfortune, who support so many +hospitals and public charities by their voluntary contributions, and +who, in so many calamities, have seen some devoted heroine issue from +her retirement to assuage them. For if the Crimean war produced its lady +beneficent in the person of Florence Nightingale, all of us must allow +that if others had followed the example of Miss Burdett Coutts, who, in +a manner, has stood alone against the storm, by the facilities she has +afforded for treating and experimentalizing on the cattle smitten with +typhus, the formidable scourge might have been arrested in its focus. + + +III. + +_Curative Medication._ + +We might acquire the means of resisting the general causes which develop +the typhus; we might stop its diffusion, we might even prevent it, by +inoculating the sound and healthy animals, and yet it would be +necessary, none the less, to search for the means of curing it; for, as +in the small-pox, the preventive treatment of which we know, certain +circumstances would arise in the disease which would oblige us to treat +it. And as we are far from being able to resist the generation and +dissemination of this scourge, which reckons almost as many victims as +sufferers, it is important to make known what treatment we can oppose to +the functional derangements to which it gives rise. + +As we have already said, this typhus, when the organism has absorbed its +peccant and infectious miasma, produces a succession of disorders which +become in a manner temporary functions; it pursues its phases, its +periods; and as the functional derangements differ at these several +epochs from the development of the morbid phenomena, the course of +medicine which is employed to check them cannot always be the same. +Starting, therefore, from practical data, we will attend the disease in +its gradual advance--that is to say, in its distinct periods--and will +afterwards explain certain predominant symptoms, which, owing to their +importance, must likewise fix the attention of the careful therapeutist. + +It will be remembered that we have recognised four periods in the +regular course of typhus:-- + + 1st, a period of incubation; + 2nd, a period of initiation; + 3rd, a period of duration; + 4th, a period of decline. + +But, in the first place, before beginning the treatment, every farmer or +grazier, or cattle-owner, who keeps a certain number of cattle, should +divide his herd into several classes, in order to regulate and methodize +the cares to be given to the sick. + +Thus, he will form a first class, comprising the animals in a sound and +healthy state, having had no intercourse, either direct or indirect, +with the tainted cattle, and which he will be careful immediately to +isolate and keep apart. + +A second class must be formed of those beasts, which, though as yet +unaffected with the distemper, have, nevertheless, been exposed more or +less directly to its contagion, by living and consorting with them, or +by their contact with other animals, either at fairs or markets, or in +the ships and cattle-trucks on the railway during their transit from one +place to another. The horned cattle composing this latter class must be +carefully watched, and be made the subject of the preventive treatment, +the moment the first sign appears of the working of the incubation. + +A third class must be formed, consisting of cattle actually smitten with +the distemper. + +These divisions of animals being thus settled and separated, will +diminish the labour and the cost of treatment and the liability to +diffuse the complaint, especially when the epizootia begins to lose its +virulence. + + +_First Period--of Incubation._ + +We have said that infectious diseases, when once the frame had suffered +the effects of the poisonous miasma, pursued their fatal course, and +that, generally speaking, it was impossible after such infection to +arrest its development. We say generally, for the typhus at the outbreak +of its appearance on a virgin soil sometimes manifests itself in a +benignant manner, then it becomes more destructive, by-and-bye its +pernicious properties decline, and it in some sort goes out of itself. +One would say that the epizootia, like those it smites, has likewise its +peculiarities, its period of initiation, of duration, and of decline. +There are in consequence fixed times or epochs during which the +sufferers afford better scope for our means of action; at a given moment +the attenuated virus, having lost much of its deadly effects, ceases to +produce death, which decline is the real source of the marvellous +successes obtained by certain remedies against the epizootia. + +If it be true that the distemper at its period of duration, and at its +most critical moment, cannot be fettered, we should not be justified in +asserting positively the same, as respects the period of incubation. +Indeed, we are convinced ourselves, that if ever this disease shall be +clogged in the wheel, _if ever its specific remedy shall be discovered, +it will be within the period of incubation_, when the economy begins to +struggle with the first phenomena of the poisoning. Be that as it may, +we cannot, in epizootic times, too earnestly enjoin the owners of cattle +to submit their animals to a strict and close inspection, in order that, +when the first signs of incubation appear, they may modify the animal's +usual diet, and attack the disease at its birth, so as to render it +abortive, if the thing can be done. + +At this period we must endeavour to come to Nature's assistance, we must +shake and stir up the economy, we must unseat the morbid functions which +seek to master us, and then the vital force, thus solicited and +stimulated, may sometimes struggle with advantage. To do this +effectually, if the animal is atonic and predisposed to adynamia, if his +internal organs are relaxed, we will strengthen him by administering +every day a stimulating beverage. If he is confined to the stall we +will give him the open air, and let him graze the fields; which is a +treatment by itself for the invalid animal, so vivifying is the pure air +of the common, and so thoroughly different from the atmosphere which is +pent up within his stall. If the animal is strong, lusty, exuberant with +health, let him be purged once or twice, the purgative to be given at +intervals of twenty-four hours. (We shall give the medical formula in +the chapter addressed to farmers, graziers, &c.) + +This purgation, moreover, will correspond with the theory of those +authors who consider the evacuations as the proper means of delivering +the economy from the infectious miasms which have been absorbed. + +If the beast is plethoric, recourse should sometimes be had to bleeding, +especially in hot and dry seasons, like the one we have recently passed +through. + +These stimulative and depletive medications cannot but be favourable to +the animal, since it will anticipate the treatment to which he must be +submitted a few days later, when the disease shall have declared +itself. + +To this treatment, in some sort preventive, must be annexed an +_antimiasmatic_ beverage, either a _permanganate of potash_, or a +solution of _chlorate of potash_, or of _arsenic acid_ in powder, mixed +with some aromatized beverage, or solution of _arseniate of soda_. These +anti-typhic drinks must be discontinued on those days when the sick +cattle are purged. + +It need hardly be said, that during this period of incubation the +feeding of the cattle must be strictly attended to, and that the animal +must receive unusual hygienic care. + + +_Second Period, or that of Initiation._ + +At this period the constitution and temperament of the sick cattle must +first of all be deliberately studied, so as to ascertain fully which are +_lymphatic_, which are _nervous_, and which are _sanguine_. We must +notice the age, the sex, the state of gestation, and make allowance for +any prior complaints to which any of the sick cattle may have been +subject. For if, like certain system-mongers, we reduced the treatment +of all tainted cattle to the same mathematical formula of medication, +that is, either to bleeding or to purging exclusively, we should +certainly increase the number of victims. + +In this stage of the disease we have to contend with the derangements of +the circulation and secretions. The fever is generally intense, the +blood is inflamed or vitiated, the mucous membranes are dried up; +shiverings, alternations of cold and heat, &c., occur. We must then +mitigate these morbid phenomena either by bleeding or purging. The +bleeding must be more or less copious, according to the strength of the +animal. For, it must not be forgotten that we have several critical +phases to pass through, and if we exhaust the animal by too largely +draining him of blood, we may forfeit the success of the treatment. If +bleeding is considered unnecessary, let the sufferer be purged at once, +by administering either _sulphate of magnesia_ (_Epsom salts_), _or +sulphate of soda_ (_Glauber's salt_). These purges to be taken daily, +for two or three days, according to the way they operate. Linseed oil, +mixed in some warm beverage, may be given instead of these, or else a +mixture of rhubarb and calomel, or even a decoction of senna. Preference +should be given to saline or laxative purges, as, drastic purgatives, +such as aloes or jalap, sometimes concentrate the inflammation on the +narrow parts of the digestive channels. + +In this second stage--the period of initiation--the appetite is +generally gone, the thirst excessive; so that nutritive or solid feeding +must of course be suppressed. + +As for the drinks, they must be cold, consisting of water with +sufficient flour mixed in it to whiten it, and a little vinegar or +sulphuric acid, to acidulate it. A decoction of good hay with some +marine salt, or nitrate of potash; a decoction of pellitory or +wall-wort, of ground-ivy, or whey, or buttermilk, likewise acidulated, +and which the cattle are very partial to, will in every way be suitable +for their use. If the heat of the skin diminishes, and if congestion +appears to settle on the lungs, the drinks must be given warm, +consisting of a decoction of borage leaves, mallows, marsh-mallow, and +pellitory. In these cases, the body must be protected from chills by +overlaying it with blankets, so as to keep the mass of the blood as much +as possible on the surface, and check the tendency it has to load the +internal organs. + +By following these prescriptions, we shall answer all the conditions of +the treatment during the second period. In truth, by the process of +bleeding, we shall have reduced the heat of the fever, and prevented too +great a flow towards the nervous, pulmonary, or digestive centres. The +purgings will have acted with similar effects; and, what is more, they +will have cleared the _primæ viæ_, and rendered the circulation of the +abdominal apparatus more easy. In fine, the drinks will have contributed +to assuage the violence of the fever. The washing, which must be +effected with a wet sponge passed over the nose, mouth, and eyes, and +then over the skin, which must afterwards be rubbed dry, will be both +useful and pleasant to the sick animal. This cleansing will maintain the +important functions of the skin in due order. + +Some persons have advocated as most efficacious at this period +hydro-therapia, or the Water-cure, in the form of warm and cold +ablutions, vapour baths, &c. This treatment, so bracing by its revulsive +action, and the powerful influence of which we witnessed for several +years in the establishment which we superintended at Belle Vue, near +Paris, might prove of some service in ox-typhus, especially in the form +of the vapour bath; but it requires so much practice, and so incessant +and watchful a care, that it is needful to have the process attended by +an experienced practitioner. + +We must remark, in addition, that the general state of the animal, and +his desire for food, will show the degree of strictness and restraint +which must be observed in regulating his diet. His instinct must be +taken by us as a guide; and if the drinks rendered nutritive by the +addition of bran, oatmeal, barley flour, or even seed of grass pounded, +are relished by him, we must indulge his desires to some extent, in +order to keep up his strength. + + +_Third Period, or that of Duration._ + +At this stage of the distemper we must watch and follow step by step the +symptoms which attend it, and come to their relief. + +All the secretions have now resumed their course; from the mucous +membranes there occurs a copious discharge, first of all serous, then +thick and muco-purulent; the breathing may be obstructed, the +diarrhoea frequent; the air infiltrates beneath the integument. The +fever is sometimes continuous, sometimes intermittent. We must satisfy +the cravings of the vital powers by administering the same beverages as +in the preceding period. Far from checking the diarrhoea, as some +advise, we must regulate the evacuations by means of laxatives, such as +tartrate of potash, sulphate of magnesia, or sulphate of soda. It is +very essential, indeed, that the mucous membranes of the digestive +channels should be free, and not irritated by the contact of solid +alimentary substances or bilious secretions. + +If the diarrhoea be too frequent or irritating, we must give the +sufferer night and morning a clyster, consisting of bran water. + +At this period we will follow the advice given over and over again by +all the physicians of the last century, and apply cauteries with red-hot +iron, or fix one or two setons either on the dewlap, the neck, or the +thighs, and these issues must be kept open by means of basilicon +ointment. It is unquestionably of the highest importance to promote all +the depurative secretions in animals whose cellular tissue is choked up +with grease and lymph. Those only have got well in which the running has +been regular and copious, and the wasting of the flesh progressive. + +If the fever is not regular, two pills of sulphate of quinine must be +given, each pill containing one gramme, one pill in the morning, the +other during the day, in order to prevent the fit, which usually takes +place in the evening. If the state of atony, of adynamia, comes on at +this period, _acetate of ammonia_ must be given, from one to six ounces, +in a pint of water, the same to be administered in two doses; only the +acidulous or alkaline drinks must be discontinued, otherwise the acetate +of ammonia would be decomposed in its passage into the digestive +channels. Finally, the eyes, the nostrils, and the mouth must be +frequently washed with an infusion of camomile, or some other aromatic +plant. + +The setons must be kept up very carefully. If the sick animal relishes +the nutritive beverages, let him have a decoction of bread, rice, +barley, or oats. + + +_Fourth Period, or that of Decline._ + +At this stage of the disease, in which adynamia predominates, everything +must tend to support the organism. The drinks must be bitter and +stimulating; beer, with plenty of hops in it, with an addition of +powdered Peruvian bark or sulphate of iron, may be given; or a decoction +of this bark, with gentian roots, centaury leaves, and hops; or again, a +beverage may be administered night and morning, made of veterinary +theriacum, of extract of juniper and alcohol; or finally, an infusion of +aromatic plants. + +If the diarrhoea be bloody and fetid, give the animal night and +morning a clyster, consisting of a decoction of Jesuit's bark, adding +thereto a spoonful of powdered wood charcoal, pounded to the finest +powder, and passed carefully through a sieve. If the running ceases, its +return must be excited by injecting in the nostrils a spoonful of +sternutatory vinegar or smelling salts. Finally, the purulent boils must +be opened, and dressed with stimulating ointment. + +At this closing period, which determines the fate of the disease, as we +say, there is a tendency to despair of the cure. Seeing the fatal course +of most attacks, we lose heart, death seems inevitable, and we yield its +prey to its fangs. But let us not despair; let us remember that, in +these febrile infectious diseases, above all, the phenomena must almost +always proceed to the last stage of exhaustion of the vital powers to +render the cure attainable. Some patients, smitten with typhoid fever or +cholera, have owed their lives to the indefatigable tenacity of the +contest _in extremis_ between life and death. + +I still see before me a choleraic patient, whom, during the epidemic of +1849, I had left in the morning at ten o'clock, passing into the cold +period. At five o'clock I returned to see him; the whole family was in +tears, and the sheet had been thrown over the patient's head, as if he +had already breathed his last. Time was precious to me at that fell +season, and I was about to retire, when I applied my finger to the wrist +of the sufferer, and felt a faint pulsation at long intervals. I threw +my coat off directly, called for flannel and essential oil of mustard, +which I had prescribed that morning. I set the example, and instantly +the whole family helped me to rub the patient in every direction. In a +quarter of an hour the heart quickened and revived, and in less than +half an hour more the circulation resumed its course; at the end of an +hour of this obstinate struggle the vital heat began to show itself--in +a word, the patient was saved. + +We must not, therefore, give up the contest until the death of the +sufferer is fully ascertained; and the same persistency should be +practised in the case of animals smitten with the typhus. If the +circulation slackens, if the skin turns cold, take a piece of wool, coat +it with rubefacient liniment, and rub the animal therewith, more +particularly along the spine. Then give him a cordial drink, and pass +_raies de feu_ over the loins. All these appliances will help to +stimulate the nervous system, and resuscitate the exhausted powers of +life. + +If, at last, we are so fortunate as to overcome the profound adynamia +which has utterly prostrated the frame, we next shall have to sustain +the sick animal by giving him decoctions of meat with sea-salt, or +sulphate of iron added to it, or a light broth, made with meat and +bread. + +Herbivorous animals, put upon a carnivorous diet, would not generally +endure it, of course; but some of them rather incline to unctuous +beverages, and even to cooked or raw meat. All men know that certain +horse trainers give race-horses a small portion of meat, especially when +the races are coming on, in order to increase their mettle and strength. + +We remember a sheep, which we saw at the Ecole d'Alfort, during our +studies of comparative pathology and the cutaneous diseases of domestic +animals, which manifested a great liking for meat, and even ate it +ravenously like a glutton. + +In convalescence, the animal must be sent into the open air, in some +fold enclosed with bars; he must be taken every day to pasture, each day +increasing the time he is allowed to feed, and gradually he will be left +to return to his usual regimen. But still it must be observed, that in +this distemper convalescence is long and slow, and very deceitful. A too +substantial course of feeding often revives the inflammation of the +intestines by irritating ulcerations not yet healed, and more than one +animal which had been looked upon as cured has perished in its +convalescence through a lack of watchful attention. + +Herbivorous beasts, therefore, incline to and digest animal food; +consequently, we must give sick oxen meat broths, pure milk, or milk and +water. With these must be mixed wheat straw chopped small, for hay or +even oat straw would swell and distend the stomachs. + +The typhus in this epizootia is not regular in its progress and +development. Frequently the nervous or pulmonary phenomena predominate, +when the treatment, such as we have just explained, must be modified. We +must also bear in mind that nature does not divide a disease into +periods, like those we have adopted to render our exposition of the +symptoms more intelligible and the treatment itself more methodical. + +If the nervous form of the disease prevails--if the animal shows +alternations of dulness and restlessness--if, pressure on the spine is +very painful--above all, if, in bulls, for instance, there is plethora, +let the bleedings and purgings be increased in order to abate the +nervous erethismus. In this form, the violence of the attack usually +carries off the beast. Should there, however, be any chance of saving +him it will be by employing this medication, which is at once revulsive +and depletive, notwithstanding the well-known fact that bleedings, far +from relieving the nervous system, sometimes aggravate its irritability. + +A general ablution with cold water may be tried in _desperate cases_. +The animal must then be immediately well rubbed, and covered with wool, +in order to excite a thorough reaction. + +In the pulmonary form of the typhus, but only during the acute stage, +the drinks must be warm and emollient, composed of a decoction of +soothing substances, with mallows, &c.; or one of linseed, to which must +be added some oxymel of squills and opium. The purgatives must be +non-stimulating; and emetics, freely diluted, for instance, will be +very serviceable. + +At the third and fourth period in this pulmonary form of the disease, +adopt the treatment prescribed for intestinal typhus. + +We might have greatly enlarged the list of the pharmaceutic agents, but +the richer a treatment is in remedies the poorer it is in cures. We have +made choice of the simplest and safest among all the remedies advised by +experienced men, making allowance for the difficulties inherent to the +number of animals, the mode of application, the cost, &c., always +keeping in view the life of the animal to be saved and the interest of +the cattle owners. + +We think that the treatment by inoculation might have prevented the +typhus in a very large proportion, and that the curative medication +might have saved many of the infected cattle at the worst period of the +epizootia. + +Such, then, are the results which will one day be obtained, when we +shall be able to supersede the barbarous process of general +extermination, by the adoption of a rational treatment, founded at once +on science and practical experience. + + +IV. + + _Hygienic Measures to be taken against the Extension of the + Contagion--Acts and Orders concerning Sanitary Police + Regulations._ + +I have purposely neglected, in discussing the various plans of +treatment, certain measures to be adopted with the object of opposing +the spread of the contagion. The memorandum published on this subject by +the Privy Council, and drawn up by Dr. Thudichum, is so complete and so +clear, that we can find nothing better to say. I recommend its perusal +to all who possess horned cattle, and who have occasion to send them to +any distance. It is of the highest importance to follow this judicious +advice, as the general interest will constitute here the safeguard of +the pecuniary interests of each in particular. I add to this memorandum +upon hygienic measures, the consolidated and amended acts and orders +published under the head of "Sanitary Police." In this way those +interested will have beneath their eyes all which it is important for +them to know, both in a medical and legal point of view. + + MEMORANDUM _on the Principles and Practice of + Disinfection, as applicable to the present Epidemic of + Cattle Disease_. By J. L. W. THUDICHUM, M.D. + + + [Sidenote: I.--Principles of disinfection.] + + I.--PRINCIPLES OF DISINFECTION. + + [Sidenote: 1. Definition of disinfection.] + + 1. The term disinfection signifies the removal and + destruction, or destruction and subsequent removal of the + products of destruction, of all matters actually being or + containing products of disease capable of reproducing + disease in other animals. + + [Sidenote: 2. May include special purification and + deodorization.] + + 2. If the same processes and means, as used for this + purpose, are applied to the purification and deodorization + of places and things not actually infected, but capable or + suspected of being infected, then these preventive measures + are practically and properly included under the definition + of disinfection. + + [Sidenote: 3. Reproducers and primary carriers of + infection.] + + [Sidenote: Infectious parts of dead animals.] + + 3. The reproducers of the infectious matter or contagion are + all kinds of cattle of the ox tribe, which also are at + present in this country the only animals liable to its + specific effects. It is probable that the contagion adheres + with particular pertinacity to all secretions and discharges + from sick animals. For this reason, fæces or droppings, + urine, ruminated food, all secretions from the mouth, nose, + and eyes, and any sore parts of the surface of the diseased + animals must be considered as the principal and primary + carriers of the infectious matter or plague poison. It is + also probable that many parts of animals which have died + from the cattle plague, or have been killed during advanced + stages of the disease, are infectious, some because they are + primarily imbued with the contagion, others because they + have been in contact with it after the death of the animal. + Skins, hides, hair, horns, and hoofs, must therefore always + be treated with precaution. The chances of infection by + flesh, fat, cleaned guts, and blood, are perhaps more + remote, but cannot be lost sight of. + + [Sidenote: 4. Particular danger of droppings, or fæces.] + + 4. The cattle plague, although affecting every part of the + animal, shows its visible effects most extensively in the + intestinal canal. It is believed, and apparently upon good + grounds, that the intestinal discharges are the principal + agents, upon the distribution of which mainly depends the + spread of the disorder. + + [Sidenote: 5. Enumeration of infected things and places.] + + 5. It follows from the above, that all articles which have + been in contact with a diseased animal, or any of its + discharges, particularly its fæces, are capable of carrying + the infection for an indefinite time, and must be looked + upon as being actually infectious to other healthy animals. + Such are racks of wood or iron; cribs or mangers of wood, + iron, or stone; articles used for fastening animals; leather + collars and straps, ropes and chains; all harness of any + animals used for drawing, and all carts, waggons, and + carriages which they have actually been drawing; the stalls + or sheds in which animals have been standing; the whole + lengths of the gutters and drains through which their urine + has been flowing; the entire surface over which their manure + has been drawn, and all implements with which the removal + has been effected; the entire dung-heap upon which infected + manure has been put, and the fluid contents of the manure + pit, or of the special receptacle for the urine; yards or + sheds in which cattle have been kept to tread down long + straw, and the whole of such straw and manure, as also the + ground beneath them; paths and roads upon which diseased + cattle have walked or been carried; fields and meadows upon + which they have been grazing; all carts, carriages, trucks + and railway trucks in which diseased cattle have been + conveyed, and all the platforms, railings, bridges, and + boards upon which they have been moved thereto; as also all + apparatus which has been used to pen, tie, lift, haul, + lower, and fix them; the clothes, and particularly shoes and + boots, and iron-pointed sticks of drivers and their dogs; + the apparel of all cattle-herds or attendants, particularly + their shoes and boots; the shoes and boots of all persons + visiting places where diseased cattle are or have been + standing; and, in general, the clothes of all persons + visiting infected places, ships, and all parts of the + platforms, stages, stairs and bridges, hoists and cranes + used for embarking and landing the animals; markets, and all + sheds, and pens, and implements used in contact with cattle; + slaughter-houses, and all persons and implements in them + which have been employed upon sick cattle, as also sundry + parts or organs which come from sick animals killed in + slaughter-houses; knackers' yards, trucks or carts, horses, + men, and implements which have been employed in the disposal + of sick or dead animals; wells and ponds from which diseased + cattle have been drinking, or into which any portion of + their excreta has had any opportunity of flowing, directly + or indirectly; all fodder, grass, hay, straw, clover, &c., + and particularly remnants of fodder upon which diseased + cattle have been feeding; and, in general, all persons, + animals, places, buildings, and movable things which have + been in contact with matters proceeding from diseased + cattle, or with such diseased cattle themselves. To the + above-mentioned places and things any of the processes and + agents enumerated and described in the following may have + to be applied. + + + [Sidenote: II. Practice of disinfection.] + + II.--PRACTICE OF DISINFECTION. + + [Sidenote: A. Disinfection by earth.] + + [Sidenote: 1. Burying of animals, &c.] + + A. _Disinfection by Earth._ 1. _Burying._--All matters that + can be buried, so as to remain covered with a thick layer of + ground or earth are innocuous. The ground chosen for such + interment should be dry. The quickest, and cheapest, and + most certain way of disinfecting an animal dead from the + plague is to bury it entire. + + [Sidenote: 2. Burying of dung.] + + 2. The droppings, and all straw and other matters + contaminated therewith, may also be buried into ground where + they are not likely to be disturbed for a long time. The + places from which such droppings have been removed to be + cleaned and disinfected as will be described below. + + [Sidenote: 3. Infected manure and compost heaps.] + + 3. Manure heaps and the down-trodden manure of cattle yards, + if they have become infected by even a small quantity of the + droppings of a diseased animal, should be carefully shifted + to a suitable piece of ground, and there be transformed into + compost heaps. A layer of manure one or two feet in + thickness should be covered all over with six inches of dry + earth, ashes, and mineral rubbish; upon this another layer + of manure may be placed, and then again a layer of earth, + and so forth, until the whole of the manure is stacked; it + should be covered all over with a continuous layer of earth + of from six inches to one foot in thickness. If the manure + heap or yard manure cannot be shifted, it may be covered on + the spot with a layer of dry earth, after which all animals + are to be kept away from it. + + [Sidenote: 4. Removal of boil infected by soakage.] + + 4. If the floor of any shed or stable in which diseased + cattle has been standing is not constructed with special + water-tight and impenetrable material, it must be assumed to + be infected to the depth of at least six inches. This ground + should therefore be removed, together with any stones, + pavements, or wood work which may have been in contact with + it, carted to a piece of dry land and buried. Half-rotten + wood is a particularly favourable carrier of infection. + Mortar, bricks, loam, or any other lining of the sides of a + pen in which a diseased animal has been standing, should be + broken out and buried. + + [Sidenote: B. Disinfection by fire.] + + [Sidenote: 1. Burning.] + + B. _Disinfection by Fire._ 1. _Burning._--All infected + articles of a minor value, or made of incombustible + materials, can be disinfected by exposing them to a heat + which will char organic matter. To this class of articles + may be reckoned racks of wood or iron; cribs or mangers of + wood, iron or stone; leather collars and straps, ropes and + chains; dry manure, residues of fodder from which diseased + cattle have eaten; and all such small articles of little + value which can easily be replaced by new ones. Chains may + be exposed to a dull red heat; all other articles may be + heated over a fire of coal, brushwood, or straw until well + scorched. All new articles of ironware should be bought in a + galvanised state, to prevent the formation of rust, the + accumulations of which form convenient seats for infectious + matter, and for the same purpose it is desirable that iron + articles which have been disinfected by heat as above should + afterwards be either galvanised, or, at least, while hot be + treated with resin, to cover them with a durable varnish, or + should be varnished or painted. + + [Sidenote: C. Disinfection by chloride of lime. General + remarks.] + + C. _Disinfection by Chloride of Lime._--Chloride of lime, or + bleaching powder, is the most powerful, the cheapest and + most easily managed of all artificial disinfectants. It can + be had everywhere, and at any time, and in quantities + sufficient for every purpose. It should as much as possible + he applied in solution, of a strength varying somewhat with + the particular purpose for which it is to be employed; and + after it has been allowed to act upon the surface or matter + to be disinfected a reasonable time, should be washed off, + together with all products of decomposition. As chloride of + lime does not destroy only the infectious matter in a + mixture, but destroys all organic matter without + distinction, it is not applicable to large quantities of + matter, such as the manure of cattle, dung-heaps, &c., + inasmuch as twice or three times the weight of these matters + of chloride of lime would be required for their effectual + destruction and disinfection. It is further inapplicable to + all matters rich in ammonia, particularly putrid urine, as + it destroys the ammonia and evolves a large amount of gases, + some of which have a repugnant odour, and are perhaps not + quite innocuous. But for the disinfection of surfaces of + things and places no better or more suitable agent than + chloride of lime is at present known to science. + + [Sidenote: D. Special directions for disinfection of + stables, sheds, &c., trucks, and ships, &c.] + + [Sidenote: 1. Special directions.] + + [Sidenote: Washing.] + + [Sidenote: Scrubbing.] + + [Sidenote: All washing water to be disinfected.] + + D. _Special Directions for the Disinfection of Stables, + Sheds, Vans, Railway Trucks, and Cattle Ships,[V] and of + Persons and Things connected with them._--1. After such a + place has been cleaned by mechanical means, scraping, &c., + as much as possible, and all manure and dirt has been + carefully buried, the entire surface which has been + contaminated, or is likely to have been contaminated, should + be covered with a layer of chloride of lime in powder. The + powder should be worked about with a broom until equally + distributed. It is intended to disinfect the water to be + used in the washing process which is now to commence. Clean + water, from a hose in which it flows under pressure, or from + a force-pump, garden-engine, or from large watering-pots or + water-cans, or poured freely from buckets, should now be + applied to the entire surface by one person, while another + at the same time scrubs the entire surface; and particularly + all crevices, joints, and irregularities. The washing water + and chloride of lime are then to be worked down the gutters, + into the sinks, cesses, or natural watercourses. No washing + water from any infected place or thing should ever be + allowed to flow into any cesspool, urine-hold, dung-heap, + pond, sewer, or natural watercourse, without having + previously been mixed and stirred with a liberal amount of + chloride of lime. When the place has thus been scrubbed + until the water flows off clean, it is ready for effectual + disinfection. + + [Sidenote: 2. Actual disinfection.] + + [Sidenote: Solution of chloride of lime.] + + [Sidenote: How applied.] + + [Sidenote: How long to be left on.] + + 2. For this purpose a solution of chloride of lime in water, + in the proportion of one pound of the powder to one gallon + of water, is made. For the lair of one animal from six to + ten gallons of such fluid should be prepared. This fluid is + now distributed over the whole surface to be disinfected, + gradually, by squirting from a syringe, or by pumping + through a force-pump, garden-engine, or by watering from a + watering-pot or can with a finely pierced rose. All + woodwork, stones, bricks, cement, mortar, all fixtures of + whatever material, should be well wetted with the solution, + and immediately be scrubbed with a hard brush. Floor and + ceiling are also scrubbed, and the whole is left in this wet + state covered with the chloride of lime solution for at + least one hour, during which time care is taken that no + parts become dry. + + [Sidenote: 3. To be washed off after disinfection.] + + [Sidenote: Flushing.] + + [Sidenote: Precautions as to direction of clean water.] + + 3. As the chloride of lime and the products of its + decomposing action upon infectious matters may be hurtful to + cattle, these matters have to be carefully washed off by a + second and final flushing. For this too much water and too + much scrubbing cannot be employed. Care should be taken to + apply the clean water always to the highest parts, so as to + cause it to flow thence to the lower parts, and to wash away + the waste from the lower parts before applying any fresh + water to the upper parts. + + [Sidenote: 4. Care not to carry back dirt by brooms, boots, + &c.] + + 4. Care should also be taken to rinse and flush every broom + which has worked away sediment and waste from the lower + parts into and through the gutters and drains before + applying it again to the clean upper parts. Care should also + be taken that the working persons should not step from the + dirty or partially cleansed places on to the clean ones, as + this may suffice to bring infection back to the disinfected + place. + + [Sidenote: 5. Disinfection of workmen and tools.] + + 5. Lastly, all persons employed in this work, having swept + and flushed the gutters with the same care as the lairs, are + collected, together with all engines and tools which they + have used, as near as possible to the sink or place of final + egress of water from the premises, and there disinfected as + will be described. + + [Sidenote: Tools.] + + The tools, such as hooks, forks, spades, hoes, barrows, &c., + are scrubbed with the above solution of chloride of lime, + and subsequently water until clean; they are then + repeatedly wetted with the solution, and after it has had + time to disinfect the entire surfaces of them, they are + washed clean and laid up, or hung up to dry. + + [Sidenote: Workmen.] + + [Sidenote: Disinfection of boots.] + + [Sidenote: Disinfection of workpeople's bodies, hands, &c.] + + [Sidenote: Changing and disinfecting clothes.] + + [Sidenote: Burning of articles of little value.] + + The workmen, then, having finished the disinfection and + flushing of all objects and surfaces, effect their own + disinfection in the following manner:--They wash their boots + most carefully with chloride of lime and water, scraping the + soles and scrubbing the seams where the soles join the upper + leather. They wash their hands and arms, and by means of + clean rags or sponges they remove any splashes from their + clothes. After this they go indoors, remove all clothes from + head to foot, wash their bodies, and particularly their + hands, faces, hair and feet, with plenty of soap and water, + and put on fresh clothes and linen. The clothes and linen + which they have taken off should be treated as infected, set + to soak immediately in boiling water and afterwards + disinfected, or in water containing two ounces of chloride + of lime to the gallon in solution, or containing four ounces + of Condy's red permanganate of potash fluid in solution; or + the clothes and linen should be put in a copper and boiled + and subsequently washed. All articles of little value which + are much soiled should be burned on a bright fire. + + [Sidenote: E. Disinfection of live stock.] + + [Sidenote: 1. Stock may carry infection in two modes.] + + E. _Disinfection of Live Stock._--1. Live cattle may carry + infection in two ways: first, by being themselves infected + with the plague and reproducing the poison; and secondly, by + accidentally carrying the poison from other animals in a + dormant state upon some part of their surface, their hair, + and particularly their feet. These latter animals may + therefore infect others without being or becoming themselves + subjects of the plague. All persons therefore buying new + animals, should disinfect them before allowing them to enter + their premises. In a similar manner, if in a stable there + has been a case of plague, the healthy or apparently healthy + animals should all be disinfected. + + [Sidenote: 2. Mode and means of disinfecting live stock.] + + [Sidenote: Warming and refreshing drink.] + + [Sidenote: Penned in the quarantine shed.] + + 2. The mode in which live animals may be disinfected, + consists in washing them with disinfectant solutions of such + strength as will destroy the contagion without injuring the + surface of the animal. A solution of two ounces of chloride + of lime in a gallon of water, is a proper solution for + washing the coat of animals. A mixture of four ounces of + Condy's red permanganate of potash fluid, with one gallon of + water, is also a proper disinfectant solution. For + full-sized cows and bullocks, &c., several gallons of either + of these solutions should be used. Great care should be + taken to keep the solution away from the eyes, nostrils, + mouth, and tender parts. When the entire surface is washed + and disinfected, all disinfectant is removed by the + application of great quantities of clean tepid water to all + parts. The animal is given a warming and refreshing drink, + and is conducted by a clean attendant to the clean + quarantine shed. There it should receive fodder both dry and + green, and sop, and plenty of pure cold water, and be rubbed + dry with whisks of straw and hay. + + [Sidenote: F. The quarantine shed.] + + [Sidenote: 1. Objects.] + + [Sidenote: Both quarantine and surface disinfection are + required.] + + F. _The Quarantine Shed._--1. The quarantine shed is + intended to keep the new and suspected cattle separate for a + period of at least ten days, in order to afford the + security, to be obtained by observation alone, that it is + not actually infected with plague. While, therefore, + disinfection of the surface of cattle removes one kind of + danger, another, which cannot be removed, can only be kept + circumscribed or penned in, and this is done by the + quarantine shed. But the keeping of cattle in the quarantine + shed would not disinfect its surface with certainty even + during a much longer period than ten days; disinfection of + the surface therefore cannot supply the precaution of the + quarantine shed, and a rigorous quarantine cannot supply the + effect of surface disinfection. Both precautions are + necessary for perfect security, although either of them, + without the other, obviates a particular kind and a certain + amount of danger. + + [Sidenote: 2. Management of the quarantine shed.] + + 2. The quarantine shed should be situated in an isolated + part of the premises. All manure and urine from it should + flow and be carried to a particular place separate and + distinct from the common dung-heap, and be buried daily. + + [Sidenote: Cleanliness.] + + [Sidenote: Persons attending healthy stock not to attend + quarantine shed, and vice versâ.] + + The utmost cleanliness should be observed in the shed. All + tools, pails, currycombs, etc., used in this shed should be + used in it exclusively and nowhere else. The person + attending the quarantine shed should not be allowed to go + into the shed where healthy stock is kept, or permitted to + approach healthy stock. No person attending healthy stock + should be permitted to approach quarantine cattle, or to go + near or into the quarantine shed. But should unfortunately + only one person be available for both duties, that person + should be allowed to approach quarantine cattle only when + clothed in the safety dress to be immediately described. + + [Sidenote: G. The safety dress.] + + [Sidenote: 1. Description.] + + G. _The Safety Dress._--1. This consists of strong + water-boots reaching up to the knees, well greased all over; + of a waterproof coat, buttoned close all the way up in + front, and closing tightly round the neck and wrists. The + head is to be covered with a cap which takes the hair well + in. + + [Sidenote: 2. Persons who should use the safety dress.] + + [Sidenote: To disinfect before leaving suspected or infected + premises.] + + 2. Every person having occasion to visit sheds in which + there is diseased cattle, or suspected cattle, or quarantine + cattle, should be provided with the above dress, put it on + when entering the place, take it off when leaving the place, + and have it disinfected immediately. This precaution should + be strictly observed by all inspectors, all veterinarians, + or others called in to attend sick cattle, by all dealers + and butchers entering sheds, yards, or meadows, for the + purpose of sale or purchase, and by all other persons coming + on the premises on business in connexion with cattle. + + [Sidenote: 3. Strangers not to enter sheds except in + disinfected safety dresses.] + + [Sidenote: Proprietors of cattle to keep safety dresses.] + + 3. The owners of stock should not allow any strangers to + enter their sheds, yards, or meadows, except in disinfected + safety-dresses; and in case this should give rise to + difficulties, they will do well to have themselves one or + two such safety-dresses at hand, and to cause all persons + whose business compels them to enter their sheds, to leave + their own boots behind, and to put on the long boots, + waterproof-coat, and special cap. Only thus can they hope to + exclude all ordinary and obvious chances of infection from + their previously healthy sheds, yards, and meadows. + + [Sidenote: H. Measures to be taken where plague has + appeared.] + + [Sidenote: Killing and burying diseased animals.] + + [Sidenote: Disinfecting the living and the stables.] + + H. _Measures to be taken on Premises where Plague has + actually appeared._--1. When the plague has actually + appeared in any shed, yard, or place, the sick animal should + at once be removed with all due precautions. It is certainly + the safest and best to pole-axe the animal at once, and to + bury it entire, and then to disinfect the particular lair as + above described, clear out the stable or shed, disinfect + the whole of it and all apparatus, also all the animals, and + only to let the animals enter the shed, &c. again, after it + is completely sweet and dry. + + [Sidenote: 2. Hospital shed.] + + [Sidenote: Situation of.] + + 2. If, however, a proprietor is desirous of keeping a sick + animal because its illness does not appear severe or fatal, + he should place it in a separate shed, which must not be the + same as or near to the quarantine shed, and be distant from + all healthy animals, and so situated that the prevailing + wind does not blow from this hospital shed towards the + healthy or quarantine shed. The water should also not flow + from this hospital shed towards the others, or the yard, or + any meadow, but should be carefully drained away and sent + off the premises by a special sink. + + [Sidenote: 3. Preventing of diffusion of fæces.] + + 3. To prevent the scattering of fæces by infected animals + (and also by suspected animals and all animals suffering + from diarrhoea), their tails should be so tied to one or + other of their horns as to protect them against being soiled + by the intestinal discharges, and to prevent them from + distributing such discharges by the ceaseless motions + peculiar to these organs. The spattering of fæces should be + prevented by a copious supply of rough straw, with some + sand, sawdust, or ashes placed behind and underneath the + animal. The straw and fæces should be dealt with as has been + described. Animals affected with plague or diarrhoea should + not be led along streets, highroads, and paths, as they + would be certain to drop infectious fæces, which would then + be distributed over the entire length of these roads by the + feet of men and animals, and the wheels of vehicles. + + [Sidenote: 4. Special management of hospital shed.] + + [Sidenote: Persons to be employed.] + + 4. The sick animals should be disinfected repeatedly; their + pens should be cleaned and disinfected repeatedly, during + the course of the illness. This should be done by persons + either guarded by the safety dress, or--and this is + safest--by such as may not come into contact with healthy + cattle, or have to enter healthy sheds. All tools, pails, + fodder, &c., to be used in the hospital shed to be kept for + that purpose only, and never to be used with healthy, or + quarantine, or only suspected cattle. + + [Sidenote: 5. Disinfection of parts of dead or killed + animals.] + + 5. If the proprietor of any dead piece of cattle, whether it + has died naturally or been killed, should decide upon + dismembering it instead of burying it entire, and upon + utilising the hide, horns, hoofs, tallow, and bones, he + should disinfect the skin, horns, and hoofs, by steeping + them for one hour in a strong solution of chloride of lime, + containing one pound of the powder in each gallon of water, + and afterwards washing them. The tallow should be thickly + powdered with chloride of lime all over, and be sent + directly to the boilers. It should not be boiled in any + vessel employed on the farm. Under all circumstances, it is + advisable to let this dismemberment of dead and fallen + cattle he performed at the knacker's yard. + + [Sidenote: 6. Flesh, &c., to be buried.] + + 6. Flesh, blood, guts, lungs, and the bones of the head of + infected animals should not be trafficked with, as they + cannot easily be disinfected. They should always be buried. + + [Sidenote: I. Disinfection of meadows, fields, roads, &c.] + + [Sidenote: 1. Meadows.] + + I. _Disinfection of Meadows, Fields, Roads, &c._--1. Meadows + infected by diseased cattle should be carefully cleaned of + all dung, by burying each dropping on the spot where it + lies, cutting out the round piece of turf with the dropping + on it, and turning it upside down. The grass on the entire + meadow should then be cut and burned. It should then be left + without any cattle for at least a month, including at least + two wet days. + + [Sidenote: 2. Of roads, &c.] + + 2. All roads, paths, streets of towns, or villages should be + carefully and frequently scavenged. All carts, vans, or + waggons used for carrying manure, should be water-tight, + caulked and painted, and should not be permitted to ooze and + drop their fluid or semi-fluid contents on the road over + which they are drawn. They should be kept clean and + disinfected, as a precautionary measure, by the proceedings + above described. + + + [Sidenote: III. General recommendations.] + + III. GENERAL RECOMMENDATIONS. + + In conclusion it must be pointed out to farmers, dairymen, + and all persons having charge of cattle, + + _That the same great measures which are known to maintain + and restore the health of human beings, will also maintain + and restore the health of cattle._ + + Pure air; dry, spacious, well-ventilated and well-drained + clean sheds; clean and dry meadows; plenty of pure water; + frequent currying and washing; the prevention of the + development, by the destruction of the germs, of internal + and external parasites, particularly entozoa; proper food in + suitable quantities, and at proper times; protection from + inclement weather; the utmost cleanliness in the removal of + manure; the storing of the manure at a great distance from + the cattle-shed, and, in addition, the most conscientious + observance of the precautionary and disinfecting measures + above described--all these measures and agents together + will secure the utmost possible health of stock and the + prosperity of the agriculturist and dairyman. But the + neglect of any one of them will make the stock liable to + become infected, and the more so the more several or all + collateral conditions of the healthy existence of animals + are neglected. The negligent man is therefore certain to + lose, to injure his neighbour by defeating his precautions, + and to damage society; but the watchful and painstaking man + will be rewarded not only by the preservation of his + property, but particularly by the consciousness that it has + been preserved by his own care and attention, and that + thereby he has also benefited the state. + + * * * * * + +This consolidates and amends the former Orders. + + (_Copy._) + + At the _Council Chamber, Whitehall_, the 22nd day of + _September_, 1865. + + By the Lords of Her Majesty's Most Honourable Privy Council. + + PRESENT. + + Lord President. + Duke of Somerset. + Earl of Clarendon. + Earl de Grey and Ripon. + Mr. Secretary Cardwell. + Mr. H. A. Bruce. + + WHEREAS by an Act passed in the session of the eleventh and + twelfth years of Her present Majesty's reign, chapter one + hundred and seven, intituled "An Act to prevent until the + 1st day of September, 1850, and to the end of the then next + session of Parliament, the spreading of contagious or + infectious disorders amongst sheep, cattle, and other + animals," and which has since been from time to time + continued by divers subsequent Acts, and lastly by an Act + passed in the session of the twenty-eighth and twenty-ninth + years of the reign of Her present Majesty, chapter one + hundred and nineteen, it is (amongst other things) enacted + that it shall be lawful for the Lords and others of Her + Majesty's Privy Council, or any two or more of them, from + time to time, to make such Orders and Regulations as to them + may seem necessary for the purpose of prohibiting or + regulating the removal to or from such parts or places as + they may designate in such Order or Orders, of sheep, + cattle, horses, swine, or other animals, or of meat, skins, + hides, horns, hoofs, or other part of any animals, or of + hay, straw, fodder, or other articles likely to propagate + infection; and also for the purpose of purifying any yard, + stable, outhouse, or other place, or any waggons, carts, + carriages, or other vehicles; and also for the purpose of + directing how any animals dying in a diseased state, or any + animals, parts of animals, or other things seized under the + provisions of the said Act, are to be disposed of; and also + for the purpose of causing notices to be given of the + appearance of any disorder among sheep, cattle, or other + animals, and to make any other Orders or Regulations for the + purpose of giving effect to the provisions of the said Act, + and again to revoke, alter, or vary any such Orders or + Regulations; and that all provisions for any of the purposes + aforesaid in any such Order or Orders contained shall have + the like force and effect as if the same had been inserted + in the said Act; and that all persons offending against the + said Act shall for each and every offence forfeit and pay + any sum not exceeding twenty pounds, or such smaller sum as + the said Lords or others of Her Majesty's Privy Council may + in any case by such Order direct:-- + + And whereas a contagious or infectious disorder now prevails + among the cattle of Great Britain, which is generally + designated the "cattle plague," and may be recognised by the + following symptoms:-- + + "Great depression of the vital powers, frequent shivering, + staggering gait, cold extremities, quick and short + breathing, drooping head, reddened eyes, with a discharge + from them, and also from the nostrils, of a mucous nature; + raw-looking places on the inner side of the lips and roof of + the mouth, diarrhoea or dysenteric purging:" + + And whereas several Orders, dated respectively the 24th of + July, the 11th, 18th, and 26th of August, 1865, have been + made under the authority of the said Acts by the Lords of + Her Majesty's Privy Council, with a view to check the + spreading of the said disorder: + + And whereas it is expedient to consolidate and amend the + said Orders: + + Now, therefore, the Lords of Her Majesty's Privy Council do + hereby, by virtue of, and in exercise of the powers given + by, the said Act, so continued as aforesaid, order as + follows:-- + + 1. This Order shall extend to all parts of Great Britain. + + 2. The said Orders dated respectively the 24th of July, the + 11th, 18th, and 26th of August, 1865, are revoked, with the + exception of so much of the said Order of the 24th of July, + 1865, as empowers the Clerk of Her Majesty's Privy Council + to appoint Inspectors within the limits of the Metropolitan + Police District, provided that such revocation shall not + affect any appointment made, or any act done, or penalty + recoverable, under any Order hereby revoked. + + 3. In this Order the word "animal" shall mean any cow, + heifer, bull, bullock, ox, calf, sheep, lamb, goat, or + swine; and the word "Inspector" shall include any Inspector + appointed under this Order, or under any of the said revoked + Orders. + + 4. Whenever the Local Authority, as hereinafter defined, + shall be satisfied of the existence of the said disorder in, + or have reason to apprehend its approach to, the district + over which his or their jurisdiction extends, it shall be + lawful for such Local Authority, if he or they shall think + fit, from time to time to appoint one or more Veterinary + Surgeon or Surgeons, or other duly qualified person or + persons, to be an Inspector or Inspectors, for the purpose + of carrying into effect the rules and regulations made by + this Order, within the district for which he or they shall + have been appointed. And the same authority may, from time + to time, revoke such appointment. + + 5. Subject to the powers herein reserved to the Clerk of Her + Majesty's Privy Council, the Local Authority within the City + of London, and the liberties thereof, shall be the Lord + Mayor; in any municipal borough in England or Wales, the + Mayor; in any Petty Sessional Division in England or Wales + (exclusive so far as relates to the jurisdiction of the + Inspector of so much of the said division as lies, within + the limits of a municipal borough for which an Inspector has + been appointed), the Justices acting in and for such Petty + Sessional Division. The Local Authority in any burgh or town + in Scotland which is subject to the jurisdiction of a + Provost or other Principal Magistrate, shall be the Provost + or such Principal Magistrate; and in any other place in + Scotland not within the jurisdiction of such Provost or + other Principal Magistrate, the Justices of the County in + Sessions assembled. + + 6. Every Inspector shall from time to time report to the + Local Authority by which he is appointed, the steps taken by + him for carrying into effect the regulations prescribed by + this Order; and the Local Authority shall certify, in such + manner as may be directed by one of Her Majesty's Principal + Secretaries of State, the number of days that such Inspector + has actually been engaged in the performance of his duty, + and the number of miles travelled by him while thus engaged. + + 7. Every Inspector shall furnish the Lords of the Council + with such information in regard to the said disorder, as + their Lordships may, from time to time, require. + + 8. Every person having in his possession, or under his + custody, any animal labouring under the said disorder, shall + forthwith give notice thereof to the Inspector of the + district within which such person resides, or if no + Inspector shall have been appointed for the district within + which such person resides, then to the Officers hereinafter + named, according to the place of residence of the person + obliged to give notice; that is to say: within the + Metropolitan Police District, to the said Clerk of the Privy + Council; within the City of London, and the liberties + thereof, to the Lord Mayor; within any other borough, burgh, + or town subject to the jurisdiction of a Mayor, Provost, or + other Principal Magistrate, to such Mayor, Provost, or other + Principal Magistrate; elsewhere in England, to the Clerk of + the Justices acting in and for the Petty Sessional Division; + and elsewhere in Scotland, to the Clerk of the Peace of the + county. + + 9. Every Inspector shalt have power to enter upon and + inspect any premises or place in which any animal or animals + may be found within the district for which he is appointed, + and to examine and inspect, whenever and wherever he may + deem it necessary, any animal within such district. + + 10. Every Inspector shall have power within his district to + seize and slaughter, or cause to be seized and slaughtered, + and to be buried, as hereinafter directed, in any convenient + place, any animal labouring under the said disorder. + + 11. Every Inspector shall have power within his district to + cause to be cleansed and disinfected, in any manner which he + may think proper, any premises in which animals labouring + under the said disorder have been, or may be, and to cause + to be disinfected, and if necessary destroyed, any fodder, + manure, or refuse matter, which he may deem likely to + propagate the said disorder. And every owner or occupier of + such premises shall obey any order given by such Inspector + for that purpose. + + 12. Every Inspector shall have power within his district to + direct that any animal which he suspects to be labouring + under the said disorder, shall be kept separate from animals + free from the said disorder. And every person having in his + possession, or under his custody, such animal, shall obey + any order given by such Inspector for that purpose. + + 13. Every person having in his possession, or under his + custody, any animal labouring under the said disorder, + shall, as far as practicable, keep such animal separate from + all other animals, and shall not, if the animal be within a + district for which an Inspector has been appointed, remove + the same from his land or premises, without the licence of + the Inspector. + + 14. No person shall send or bring to any fair or market, or + expose for sale, or send or carry by any railway, or by any + ship or vessel coastwise, or place upon, or drive along, any + highway or the sides thereof; any animal labouring under the + said disorder. + + 15. No person in any district for which an Inspector has + been appointed shall, without the licence of the Inspector, + send or bring to or from market, or remove from his land or + premises, any animal which has been in the same shed or + stable, or has been in the same herd or flock, or has been + in contact, with any animal labouring under the said + disorder. + + 16. No person shall place, or keep, any animal labouring + under the said disorder in any common or unenclosed land, + or, if the animal be in a district for which an Inspector + has been appointed, in any field or pasture, where, in the + judgment of the Inspector, such animal may be likely to + propagate the said disorder. + + 17. All animals having died of the said disorder, or having + been slaughtered on account thereof; shall be buried with + their skins, and with a sufficient quantity of quick-lime, + or other disinfectant, as soon as practicable, and shall be + covered with at least five feet of earth, or shall, in + districts for which an Inspector has been appointed, with + the consent of the owner, be otherwise disposed of; in + manner directed by the Inspector. + + 18. During the continuance of the "cattle plague" within + the said City of London, or that part of the Metropolitan + Police District which is under the jurisdiction of the + Metropolitan Board of Works, no animal shall be brought or + sent to the Metropolitan Cattle Market, or any other market + within the said City or the said part of the Metropolitan + Police District, except for the purpose of being there sold + for immediate slaughtering; and every such animal, as soon + as sold, shall be marked for slaughter, in the manner in + which cattle are ordinarily marked for slaughter in the + Metropolitan Cattle Market. + + 19. Whenever any Local Authority, as hereinbefore defined, + declares, by notice published in any newspaper circulating + within his or their jurisdiction, that it is expedient that + animals, as hereinbefore defined, or some specified + description thereof, shall be excluded from any specified + market or fair within that jurisdiction, for a time to be + specified in such notice, it is hereby ordered, that after + the publication of such notice, it shall not be lawful for + any person to bring or send such animals or description + thereof into such market or fair: provided always, that this + clause of this Order shall not, unless renewed by a further + Order, be in force after the expiration of three calendar + months from the date of this Order. + + 20. Every person offending against this Order shall, in + pursuance of the said Act, for every such offence forfeit + any sum not exceeding twenty pounds which the Justices + before whom he or she shall be convicted of such offence may + think fit to impose. + + (Signed) ARTHUR HELPS. + +FOOTNOTES: + +[R] Since these lines were put into the printer's hands, the French +Government have proposed to other nations to take measures collectively +to prevent the pilgrimage to Mecca continuing to be a cause of the +spread of cholera. We hasten to render justice to this prudent +initiative. But why not take the same measures against typhus which are +judged necessary against cholera? + +[S] The typhus which broke out fifteen days ago near Roubaix, in France, +bordering upon Belgium, where the epizootia rages, appears to have been +stifled in its focus by the instantaneous extermination of the whole +herd in which it declared itself. + +[T] "It is amusing to read authors of the last century on the treatment +of this disease. They were far more confident in their powers than we +helpless creatures pretend to be. The directions given are full and +distinct, and in chapters boldly headed 'The Cure.' The beast is to be +bled, washed, and hot vinegar and water, with aromatic herbs, may be +placed in the stable to revive the cattle. The animal must be rubbed a +quarter of an hour, both morning and evening, and the bags of a milch +cow should be anointed morning and evening with warm oil. A rowel is to +be made in the dewlap by taking a skein of hemp, tow, or twisted +packthread, a foot long, and as thick as a man's thumb. _The +prescriptions are most amusing._ They may serve to entertain those who +want the cure at present, and for this reason I reproduce one or +two."--_Gamgee, Letter on 21st August._ + +[U] Dr. Letheby reported that 12,916 lbs., or more than five tons of +meat, had been condemned in the City markets during the past week as +unfit for human food. It consisted of 64 sheep, 4 calves, 7 pigs, 142 +quarters of beef, and 361 joints and pieces of meat; 5377 lbs. were +diseased or from animals that had died of disease, and the rest was +putrid. All of it was destroyed. Yesterday, a sub-committee of the +Metropolitan Plague Committee, at a meeting at the Mansion House, passed +an unanimous resolution, on the motion of Mr. Brewster, recommending +that, as unexpected and insuperable difficulties had arisen in carrying +out the purposes for which they were appointed, the money already +subscribed should be returned to the subscribers, after deducting, _pro +ratâ_, the expenses already incurred. + +[V] For the disinfection of railway trucks and cattle ships, see Special +Memorandum. + + + + +THIRD PART. + +_To Farmers and Graziers._ + + +You would have had just cause to reproach me with a want of common sense +if I had obliged you to read a book of two hundred pages, and to lose +your time in looking for the advice you will require, if the cattle +plague should visit your stalls and herds, instead of being able to turn +at once to the matter which concerns you. I have taken up my pen on +purpose to be of service to you; this is my principal duty, which I am +now going to fulfil by summing up in a few pages the most important +facts which have been described in the two first parts of this work. + +The cattle plague, which has lately fallen upon horned beasts, is a +plague, no doubt: but there are different species of plagues, and it is +necessary that you should know that this disease is one arising from +the absorption of seeds and germs with which the air is impregnated, and +which is drawn by the animals into their bodies when breathing the air +around them. When these germs, these infectious poisons, have penetrated +into the lungs and blood of the animals, these seeds of infection remain +there from eight to twelve days without producing any very perceptible +effects; but after that time the tainted animal becomes dejected, loses +his appetite, is seized with fever, laborious breathing, and +diarrhoea, to which sum of disorders in the health of oxen, cows, &c., +the name of _typhus_ has been given; or, as this distemper is contagious +in the highest degree, it has also been called the _contagious typhus_. + +You may compare this disease, in order to form a more precise idea of +it, to the small-pox, which sometimes afflicts your children, or to +typhoid fever. These complaints, which are familiar to most of you, have +some resemblance to the typhus of the ox. Only in the small-pox, which +is caught by contagion, and which seldom attacks more than once, like +typhus, the disease is localized on the skin; whilst in the cattle +plague the internal organs are the principal seat of the evil. + +This comparison will show you at once that the cattle plague, or rather +the cattle typhus, can only be cured when the disease has run its full +course, as you have observed in a person tainted with small-pox; so that +your task must be to help the sick animal to endure his complaint until +the end, or until he is cured; and you must not attempt to check it by +violent means, for if you did you would hasten the death which you +desire to prevent. You will likewise understand that if the disease--as +is certainly the case--does not attack the same animal twice, it would +be very beneficial to inoculate the animal whilst he is sound and +healthy, whenever this scourge threatens--as in the present time--to +attack all cattle. Perhaps you may be told that inoculation, which +prevents small-pox in man, cannot be applicable to cattle; that animals +inoculated with the virus of the typhus have all died of the +consequences of the operation, and so on. To all these objections you +will answer, with that downright good sense which belongs to your class, +_that Nature cannot have two weights and two measures_; and that if the +inoculation of the typhus kills animals, whilst the inoculation of the +small-pox saves men, both maladies being governed by the same laws, it +is the inexperience of physicians, and not the operation itself, which +must be made to account for it. + +In a word, to sow virus is to reap it; but there are many ways of sowing +it, and one man will reap a rich harvest, whilst another shall gather +nothing but tares. Let those unbelievers say what they like, and take my +word for it, that we shall one day cure typhus as frequently as we do +small-pox, by inoculating it, and when it appears in spite of that +course, by treating it medicinally. + +This contagious disease is very frequent in certain countries, +principally in Russia and Hungary, on the banks of the great rivers +which empty themselves into the Black Sea. In those remote countries, +when the seasons are either too rainy or too hot--and you know what a +summer that of 1865 has been--the pastures generate the pestilential +poisons of the typhus, the cattle absorb these destructive principles, +and die of them. + +But as the herds of cattle in those countries are bred for sale, and are +sent for that purpose to other countries, to France, Italy, England, +&c., the animals which have had the germ of the disease transport it +with them wherever they go. Thus, it is certain that some oxen conveyed +from Russia and Hungary, where the typhus frequently rages, brought the +disease with them into Great Britain in the month of last June; and as +the complaint is communicated from one animal to another, and afterwards +at great distances, it spread with great rapidity over England and +Scotland. So great are its powers of contagion, that some of the cattle +sent back from England have transmitted the disease to Holland, in the +first place, and afterwards to Belgium; and it was feared at one time +that all Europe would be invaded by it. + +The first belief was--and everything tends to make good the +opinion--that the typhus originally came from abroad; but many +respectable authorities, seeing the foul and nauseous state of the +stalls and cowsheds both in London and elsewhere, the overcrowding of +the animals, and the general neglect to which they are exposed, have +asserted that the disease had its origin in London. This, we repeat, is +not likely to have been the case, but it is not absolutely impossible; +at all events, there can be no question that the grievous conditions in +which some of your brethren keep their cattle have contributed to spread +the distemper, independently of other causes. + +Moreover, it is necessary to tell you, that sheep and horned cattle are +of all living animals those which are most sensitive to the influence of +contagious diseases. Every year you see instances of this fact in your +own fields and meadows. Your sheep, you all know, easily contract the +small-pox, worm diseases both on the skin and in the interior of the +body; your oxen have aphthous diseases, disorders of the blood and the +lungs, scabs and carbuncles--diseases which are all more or less +contagious, and which are generally brought on by want of care, and, +above all, by improper feeding: by which you see how much of the +sufferings of the cattle, and of the heavy losses to you which follow +them, depends upon yourselves and may be avoided. Besides, these poor +creatures, which some of you treat so harshly, are extremely +susceptible, and the blows they receive may easily affect their whole +mass of blood. You must, therefore, for your own sakes, treat them more +kindly and gently. + +Therefore, the typhus which was imported from Russia into England, +finding your cattle in such wretched conditions of cleanliness and +health, was propagated amongst them with fearful rapidity. When once the +disease had developed itself within your sheds and stalls, it would have +been the wisest plan immediately to kill the sick cattle, or to treat +them medicinally, carefully abstaining from driving to market any of +your beasts which had been exposed to the contagion. But unfortunately +you did not act in this manner; many amongst you could not put up +patiently with your losses, and only consulting your private interest, +to the detriment of the general good, you sold your sick cows and oxen, +and sowing the contagion about the country and through the markets, the +scourge was soon scattered in every direction, so that instead of +stifling the disease at its birth everything was done to propagate and +diffuse it. + +Now, if we add, that the germs of this typhus penetrate everywhere, that +it is sufficient to convey sick cattle along the public roads, and by +this means to pass near farms and meadows containing healthy cattle, to +transmit the contagion, that these noxious germs impregnate your own +clothes, the fleece of sheep, and every article, implement, and vehicle +used in agriculture, you cannot but see how often, though unwillingly, +you must have disseminated the evil far and wide. + +The germs, the miasmata of the disease, insinuate themselves not only +upon animals and men, but they shed their virus upon the grass of the +fields, the walls of the stalls and stables, and every agricultural +utensil. Every tainted animal scatters the pestilential and contagious +germs, not only by the air he expires, but by his droppings, and after +death by his mortal remains--his hide, his horns, his entrails, his +flesh--all of which disseminate the deadly germs into the atmosphere, +which afterwards diffuses them in every direction. + +The germs of this virulent distemper have no doubt smitten some cattle +which appeared in the best health and conditions, those of the rich as +well as those of the poor; but, just in the same manner as the cholera +chiefly fixes itself upon the sickly, the ill-fed, the unclean, upon +those who live in crowded dwellings and badly ventilated rooms; so, too, +does the typhus choose its victims among the stalls and stables of those +graziers who keep their cows tied up for years to the rack, giving them +neither air nor exercise, and feeding them, not on that diet which their +health requires, but on those things which add to their milk and +increase their flesh. It follows, of course, that the greater number of +these cows, more or less disordered by this long course of baleful +treatment, and many of which die of consumption, after their +deteriorated milk has infused into men the seeds of diseases, must +afford an easy prey to the typhus, _to receive which they seem almost +expressly to have been trained_. + +It is highly important then, farmers and graziers, that you should be +able to recognise this ox-typhus; in the first place, that you may take +the necessary measures to prevent its contagion; and secondly, that you +may apply the treatment which shall have been recommended to you. + +You must at all times, but above all when the contagious disease is +raging, keep a watchful eye on your cattle. If you notice in their gait, +in their looks, about their ears, any unusual signs; if they seem to you +less eager, less active, less vigilant, if they leave any part of their +rations when in the stables, or if, when in the fields, they no longer +browse with that continual alacrity which sometimes it is difficult to +divert them from, be upon your guard, and dread the outbreak of the +complaint. If to these changes of minor importance is added an appetite +really less acute, if the rumination is less regular, if the animal +looks sad and dispirited, if he exhibits an unwonted look of gloom, if +his leaden eye continues fixed, astonished, be sure a morbid change is +inwardly at work, and that this cruel distemper is spreading through his +frame. + +By-and-bye the animal loses his appetite more and more; rumination is +shorter and less frequent; he holds his head down, his ears sink and +fall; he grinds his teeth. Then as to the cows: their milk, which was +already diminished, suddenly dries up altogether, and that lowness of +spirits which had been visible for some days before, passes into stupor. +If at this time you touch their horns, their extremities, their hide in +any part, you find that all these different parts are sometimes warm, +sometimes cold. From this day forward you will witness, one by one, a +succession of disorders in the animal's health: partial shiverings at +the attachment of the fore and hind limbs, loud panting breathing, with +slight cough, the urine scanty and thick, the droppings hard and +constipated, and finally, general excessive warmth. If you press the +back the pressure will be painful, and all the signs of intense fever +will be manifest. + +Already these indications have divulged the nature of the malady you +have to deal with; but others more significant succeed them which remove +every doubt. The breathing becomes more hurried and oppressed, more +puffy; from the eyes, nostrils, and mouth there issues a discharge +which, thin and irritant at first, soon becomes thick and purulent, and +of a fetid smell. Diarrhoea takes the place of constipation; the +sexual organs of the cow are red and inflamed, and furrowed with livid +streaks. The cattle grow leaner and leaner, some of them dying at this +period. If they still hold out, the diarrhoea becomes more frequent, +more fetid, and sometimes bloody; gases are developed under the skin, +along the spine, where they form wide flat tumours, which crackle when +pressed upon with the fingers. Finally, the mucus which runs from the +head becomes still thicker and more fetid; a glutinous foam stops up the +mouth; the eyes, filled with humour, sink in the orbit; the bodily +warmth decreases, the animal sways his head from right to left, becomes +insensible, cold; his head lolls on one side, and he dies, panting, from +exhaustion and asphyxia, the tenth or twelfth day after the disease has +been confirmed. + +The carcass exhibits a repulsive appearance; the hide is dry, +excoriated, and cracked; it sticks to the bones, which show the form of +a skeleton, and the putrid decomposition, which had already set in +before death, seizes rapidly on all the tissues. + +The course of the disease is not always the same. Sometimes the animal +is agitated at first, and all the functions of life are so disturbed +that death comes on in the two or three first days. At other times, the +lungs are more affected than the other internal organs; the cough is +more intense, the breath hurried and obstructed, the excess of mucus +preventing the air from passing into the chest. + +When once you have seen this disease it is impossible to mistake it for +any other, unless it be the chest complaint called peripneumonia, which +is likewise contagious. But in this disease, as the Report of the Royal +Agricultural Society states, the attack is generally insidious; the eyes +preserve their vivacity, and the appetite is not lost until towards the +close. A short, dry cough shows itself from the outbreak, and persists. +The breathing is frequent and painful; the sides of the chest when +struck with the fingers give out the hard, solid sound of a full barrel, +this percussion being painful. The eyes, nose, and mouth do not +discharge those purulent secretions seen in typhus; the diarrhoea only +comes on at the end, being less frequent and fetid. In the milch cows +the milk decreases, but is not quite suppressed. The heat of the horns +and lower extremities is retained. The peripneumonia, in a word, runs +its course more regularly, and carries off the animal about the fourth +week. Thus it will be seen that the two distempers widely differ in +their symptoms. + +Every beast which dies of the contagious typhus, bears on its digestive +organs the traces of the malady, more or less strongly marked. The third +and fourth stomachs and the intestines exhibit red or livid patches, and +at other times ulcerations. + +The cattle plague is by far the most formidable malady which can affect +animals. When left to itself, or treated without discernment, it carries +off ninety cattle out of a hundred. In prior visitations, especially +that of 1750, when six millions of horned beasts were swept off in +Europe, England lost from three to four hundred thousand; and we may +suppose that the number of cattle which have perished since last June +exceeds sixty thousand. + +_The treatment_ is very difficult, owing to the contagious character of +the disease, and it has given rise to much discussion. In some +countries, the governments, considering the distemper incurable, only +seek to stamp it out wherever it may appear. They slaughter all the sick +cattle, and even those which had come near them, allowing a compensation +of half the value of the beast. This measure has not always proved +successful, the disease having in spite of it sometimes extended over +the whole of the country thus defended from its diffusion. + +England protected by the sea, and which has been spared for a century, +was taken somewhat unawares, so that some uncertainty has been witnessed +in the measures employed to arrest its course. In some districts, the +parties interested have had the good sense to form assurance funds; and +it is much to be regretted that the same plan has not been adopted for +the metropolis. + +But we cannot help what has been done; let us, therefore, be reconciled +with the past, and see what is best to be done in future for the +interests of all. What is the present state of the matter? A certain +number of districts, both in England and Scotland, are still exempt from +the typhus; in others the disease is generally extending its ravages. + +Those districts which hitherto have been spared, should institute +assurance funds, and take every precaution to secure themselves against +this scourge. In France, in Belgium, even in Great Britain, some places +managed, in 1750, to successfully protect themselves by prohibiting the +importation of any foreign cattle or animal. These preventive measures +may now be taken with some chance of success in certain parts. Ireland, +which, thanks to the published Orders in Council, seems to have escaped +up to this time from the contagion, shows us the effectual results of +these sanitary measures. + +As for the districts already infected, it is of the highest importance +to send no more tainted beasts to the different fairs and markets, +otherwise the distemper will spread indefinitely: the unsold cattle, the +sheep, the pigs, which are placed only a few yards apart, must +necessarily convey the contagion everywhere. It would even be necessary +at this time not to collect oxen and other animals together in the same +markets; we urgently invite the attention of all public authorities to +this most important question. + +At all events, the farmers and graziers who, after all the cautions they +have received, all the orders which have been published, and all the +dangers which have been clearly exposed to them, should still persist in +driving their cattle out of their abodes, would deserve censure, and +ought to be heavily fined. The best they can do, since the contagion has +not been prevented, is to submit their cattle to the treatment which we +are now going to explain to them in detail. + +It has been abundantly proved by the many convictions at the various +police courts, that the flesh of cattle seriously diseased has been sold +to the consumers, to the great injury of the public health; and if the +cholera, which is steadily and surely advancing towards us, should mix +its fatal germs with those of the ox-typhus, we must all expect +deplorable consequences, in case the flesh of tainted oxen should +continue to be sold by the butchers, as during the last three months it +has been. + +Every farmer or grazier who shall have fully ascertained that the ox +typhus has insinuated itself into his farm or his stables, must +instantly have recourse to the necessary measures and safeguards by +means of which he may limit its pernicious influence, and prevent the +spread of the contagion to his other cattle still sound and healthy. Let +him immediately divide his stock of animals into three classes or +lots--the first class must consist of healthy cattle, having had no +direct contact with the infected beasts; the second class must contain +those cattle which, though not yet sick, may become so, because they +have been in contact with those tainted; the third class will be +composed of cattle smitten with the typhus. + +The sound and healthy cattle forming the first class must be removed +from the farm, and driven to the field separately, by some other road, +in different pastures, and only after the dispersion of the morning +mists. Those which are accustomed to continue at the rack must be taken +out twice a day, for the twofold object of taking wholesome exercise, +and allowing their stalls and sheds to be cleaned. + +Their feeding must be attended to and watched with very particular care; +the rations of those which were being fattened up must be decreased, and +they ought to be sold to the butcher for consumption as soon as +possible. Let the following provisions be added to their daily +sustenance: + + Pounded oats 4 pounds. + Pounded juniper berries 1 pound. + Powdered gentian 1 ounce. + Sulphate of iron 2 drachms. + Carbonate of soda 2 " + +The herdsman who tends the cattle whilst feeding in the fields must have +them cleaned every day: he will carefully wash and scrub them; he will +not allow them to drink out of the ponds, or at any stagnant and muddy +watercourse. + +Those belonging to the second class must receive the same strengthening +and tonic ration in the morning; and, twice every day, one of the +following anti-contagious preparations: either a solution of _chlorate +of potash_ or of _permanganate of potash_; two drachms of either of +these salts dissolved in eight ounces of warm water, mixed afterwards +with a gallon of an infusion of sage or hyssop, just at the time when +the drink is given to them. + +Or you may employ, for the same purpose, a solution of arseniate of +soda--two grains dissolved in four ounces of water, and mixed with +their drink in the same way. You need hardly be told that these doses +must be reduced one half, when you have to treat a calf or a heifer, and +that the same diminution will hold good, in their cases, for all other +medicaments. _The use of these anti-contagious drinks is of the highest +importance; I recommend you earnestly to study their effects, and to +continue them even after the distemper shall have broken out._ + +These drinks having no disagreeable taste, the cattle take to them in +general; should the contrary be the case, give them in a bottle as all +men who are cattle owners know how to do. + +If the health of any of these animals among which the outbreak of the +typhus is apprehended should seem below the standard, you must apply a +purgative to those whose bowels do not operate well, and even have +recourse to bleeding in exceptional cases. + +During the absence of those cattle which are undergoing the preventive +treatment, let the hygienic conditions of their stalls and sheds be +looked to; for no circumstance must be overlooked or neglected if we +hope to withstand the propagation of so formidable a malady. Be careful +to take out the litter every day, to wash the floor and cleanse it of +the droppings, to ventilate the place thoroughly, to fumigate it with +burnt sulphur or aromatic plants, such as juniper berries, sage, +rosemary, salted with nitrate of potash and arsenic acid; in order to +promote the combustion and give effect to its disinfectious properties. +At night, camphor or tar, or naphthaline, or creosote, or even iodine, +may be left in the stable to diffuse their vapours; all these measures +are very effectual in modifying the air. + +Let us now see what must be done with respect to the sick animals +themselves. + +The typhus, as we have said, when once it is developed in an ox or cow, +usually pursues its fatal course until the last period of its cure; +generally death alone can arrest its march. Besides, the disorders which +this disease produces in the various functions of the body are not the +same at the different stages of its duration. Thus, for instance, the +fever produces great excitement in the beginning, but later it produces +exhaustion. Without being a physician, a man can understand that the +treatment to be applied to these different states ought not to be the +same. We must, moreover, observe that the typhus is of all known +distempers the most difficult to treat. It requires in the doctor a +degree of skill, of practical experience, vigilance, decision, and +sureness of hand which no man can be expected to possess at the first +outbreak of the epizootia. + +On the other hand, the constitution of the ox, so easily shaken, +undergoes in two weeks all the commotion which a man labouring under +typhoid fever would be subject to in a month. The phenomena succeed each +other with terrific swiftness, leaving scarcely time for us to act, or +for the medicines to operate. Do not, therefore, marvel at the great +mortality among your cattle, and at my repeated recommendations of the +preventive treatment by means of inoculation. + +At the outbreak, you must reduce the violence of the fever, prevent the +derangements in connexion with the nervous centres, assuage the thirst, +empty the stomachs and intestines, which will be the principal seat of +the complaint, and sometimes let blood. + +But how are you to obtain these results? By abolishing the solid +feeding, which is easily done, since the animal has lost his appetite. +Give him to drink, three or four times a day, half a pailful of a +decoction of good hay, adding thereto a sprinkling of salt; or a +decoction of wall-wort, with a drachm of nitrate of potash; or water +whitened with bran and flour, or whey, with a little vinegar. If the +animal has a tendency to cold, if he coughs, if his breathing is +oppressed, give him warm drinks, consisting of an infusion of mallow +leaves and borage, or else a light decoction of barley and oats, and +cover the animal's body warmly over. + +Now, with respect to purgatives: give the animal, night and morning, +according to the effect produced, 6 or 8 ounces of Epsom salts (sulphate +of magnesia), or an equal dose of Glauber's salt (sulphate of soda), +dissolved in two pints of honey-coloured water; or 12 ounces of linseed +oil in some warm drink; or a decoction of senna leaves and prunes, with +an ounce of sulphate of soda added thereto. + +We might point out a larger number of purgatives, but we shall desist +from so doing. Those which we have just prescribed, not being irritant +to the intestines, are the best which can be employed. + +If the animal is very restive, if he passes through alternate fits of +dejection, stupor, and great excitement, you must have recourse to +bleeding, particularly local bleeding, by opening the small veins of the +head. If the excitement does not abate you must add, night and morning, +to one of his drinks, 2 grains of extract of belladonna, or a half ounce +of powdered belladonna leaves. If the fever, at first, is irregular, and +tends to become malignant, you must then have recourse to sulphate of +quinine, 20 grains in the morning, and the same quantity during the day. + +When the disease is principally seated in the lungs, add to one of the +pectoral drinks 4 ounces of oxymel of squills, and 2 grains of opium, +giving also an emetic--5 grains of tartar-emetic to 4 pints of water--to +be taken in four times, at intervals of two hours. + +Whilst this medication is applied to the internal organs, let the animal +have unusual care taken of him; let his head be washed several times a +day with vinegar and water. + +Such is the course of treatment to be adopted during the first three or +four days. It must be, of course, followed methodically, watching and +obeying the signs of nature. The purgatives must not be given on those +days when the sick animal is bled, and the doses must vary with the +effects they produce. + +From the fourth to the seventh day the symptoms change, diarrhoea +shows itself, and the running appears at the nose, mouth, and eyes; you +must then continue the use of purgatives, but the dose must be weaker. +Those mentioned above are suitable in every way. The drinks, too, +continue the same. Sometimes, at this period of the disease, the animal +is utterly cast down, nothing can draw him from his stupor: he lies down +the whole day; in this case you give him acetate of ammonia, from 1 to 6 +ounces, in a pint of water, gradually increasing from 1 to 2 ounces a +day, according to the effect produced; and meanwhile, plain +non-acidulated drinks should be administered. + +At this stage of the disease it is right to assist the depurative work +of nature. This is effected by inserting a seton in the neck, and the +secretion of this issue is kept up by means of such an ointment as the +basilicon with powdered cantharides. Finally, the mouth, nose, and eyes +must be washed very often with an infusion of camomile and sage. + +At the last period of the distemper, the beast sinks into a state of +general exhaustion; his life seems all but extinguished through excess +of weakness. You must now sustain and keep him up by every possible +contrivance; give him bitter and stimulating drinks, beer diluted with +water, adding thereto some powder of Peruvian bark, or sulphate of +quinine. This is prepared by steeping in 8 pints of boiling water, +Peruvian bark, gentian root, centaury leaves and flowers, and hops, 1 +ounce of each; or else prepare a drink consisting of veterinary treacle, +extract of juniper, 1 ounce of each, dissolved in 2 ounces of alcohol, +and then mixed with 3 pints of water. + +When the diarrhoea becomes fetid and bloody, give, night and morning, +a clyster composed of a decoction of Peruvian bark, and a teaspoonful of +powdered charcoal from the poplar, well sifted. If the running from the +nostrils begins to stop, you must inject into the nasal orifices some +spoonfuls of a sternutatory solution, thus composed-- + + Spanish pepper 1 ounce. + Essence of turpentine 1 " + Camphor 2 drachms. + Vinegar 2 pints. + +Should any sores form on the skin, or should they arise from the opening +of purulent deposits, dress them with the following ointment-- + + Acetate of copper ½ a drachm. + Calcined alum 20 grains. + Sal ammoniac 20 " + Camphor ½ a drachm. + Common ointment ½ an ounce. + +If the natural heat diminishes greatly, if the chill reaches the hams +and skin, let the beast be rubbed all over, three times a day, with +wool, moistened with the following liniment-- + + Laurel oil ½ an ounce. + Green soap ½ " + Volatile oil of lavender ½ a drachm. + Solution of ammonia ½ " + +Simultaneously with the above, give the following cordial, to be drunk +in two draughts-- + + Cinnamon ½ an ounce. + Extract of gentian 1 ounce. + Red wine 2 pints. + +Should the animal fall into a state of lethargy, you must have recourse +to strokes of fire, according to surgical usage. + +This distemper must extend to its extreme degree of gravity before it +advances towards its cure; you need, therefore, not despair until the +last moment. At this period of exhaustion, the drinks above-mentioned +are given up, or you add nutritive beverages to them, such as beef-tea, +fat soups, milk, and farinaceous drinks. + +If the animal holds on, and his appetite returns, which will be shown by +the desquamation of the nostrils, by the return of rumination, by the +habit of the beast to look right and left, to question you in a manner, +add cut straw to his nutritive drinks: send him out every day into the +open air, and let him return by slow degrees to his habitual feeding. +But it is extremely important to watch the intestinal functions; to +diminish and change the food, if the diarrhoea returns; as such +relapses often cause the death of an animal considered out of danger. + +Such, then, farmers and graziers, is the treatment to be opposed to the +ox typhus: it is simple as respects the remedies, and I have deemed that +it ought to be so, in order that the medicines prescribed might be had +everywhere, and at a cost which the poor man could command as well as +the rich. The disease is variable, it is not always equally deadly; and +there comes a moment when in some sort it cures itself, with a little +assistance and watching. The great point is, to be careful and vigilant, +to attend to nature and the instincts of the suffering cattle, and lend +yourselves to both. + +I cannot reproduce here the instructions given by the Privy Council to +protect your cattle from contagion, and above all not to propagate it, +but I shall refer you to Doctor Thudichum's _Memorandum_, page 257. This +exposition is too complete to need anything added to it by me; study it +well; let it be your monitor and guide; read it over again and again; +your own interests and those of the whole country depend on the manner +in which you shall treat this admirable warning. + +There are in this disease, as in every other, unforeseen varieties and +complications, such as those which are brought on by the gestation and +abortion of cows, and those proceeding from prior disease; for these +accidents you will provide. Moreover, such a terrible distemper can only +be treated according to the advice of a professional man. Call him in, +then, follow his advice and prescriptions with rigid exactness, and do +not attempt to do better than he; and, above all, arm yourselves against +the insidious pretensions of quacks and charlatans, whatever mantle they +may put on to hide their ignorance. + + + + +FOURTH PART. + + _Suggestions on the Improvements to be effected in the Study + of Medical Science, in order that we may be in a Condition + to confront Diseases generally, but Epizootic and Epidemic + Diseases in particular._ + + +The epizootia of bovine typhus which is now extending its unrestricted +ravages over this island, and which has assumed the magnitude of a +general calamity, has naturally excited and stirred up the public mind. +Thoughtful and earnest men could not look on and witness unmoved the +ever progressive march of the scourge; but each observer has, +consistently with his means and qualifications, striven to find a remedy +to resist the evil. Thus, we have seen, and with respectful interest we +have watched, the gentlemen of the press, and other men of letters, +economists, scientific men, and, above all, physicians, producing from +day to day in the newspapers articles and letters of remarkable merit +on the all-engrossing subject of this epizootia. The re-opening of the +medical colleges furnished the skilful professors at their head with a +seasonable opportunity to consider this dire distemper, according to the +views of general pathology and medical philosophy, and this they have +done with unquestionable talent and ability. Still, something remains to +be said on this important matter, and since I have taken up my pen, like +others, I wish to mingle my voice with that of my brethren, and inquire +whether the time is not come to avail ourselves more fully than we have +done yet of the grand discoveries of the exact sciences, which, with +respect to the science of medicine, are the instruments of its progress. +And my object in doing so, is, that we may, as far as possible, rise to +a level with the ordeal which the future may have in store for us. + +Medicine is at once an art and a science. An art it has been at all +times, and in every age of civilized man; but it became a science only +when human knowledge had acquired a certain expansion; when natural +phenomena had been tested and explained; when mathematics, physics, +chemistry, botany, general anatomy, general pathology, had enabled the +inquiring physician to study with important results whatever belongs to +his theme; to understand the serial chain and connexion of bodies with +each other, in the mineral, vegetable, and animal kingdoms, and to +investigate their immutable laws. Uric acid, as we see with the +microscope, will always crystallize in rhombohedrons, according to a +fixed law; the vegetable cell, the germination of a seed, must obey, and +always submit to, the innate and indestructible forces inherent in them. +That which is true in the vegetable is true in the animal world, as +regards the pre-established order which regulates and controls the +phenomena of life. These laws which govern the development of organic +phenomena being immutable and everlasting, permit the different +generations which succeed each other on our globe to build upon a +durable basis, which certifies to the slow and laborious, but +irresistible march of human progress. + +Medical science being in truth only the application of other positive +sciences to the preservation of health and the cure of diseases, +continues like them to perfect itself incessantly; but all it can do is +to follow them at a distance, and it can never hope to reach their +degree of superiority. + +These are truths which have been long admitted and felt by us. +Therefore, we have appealed for assistance to the discoveries of the +natural sciences: physics, chemistry, have in our hands become effectual +means of observation and analysis; and we, in our age, gain more +knowledge in fifty years than our forefathers did in several centuries, +for they were then necessarily rather artists than scholars. In a word, +medical science or biology is constituting itself, and if it be fully +conscious of its impotence in the case of many diseases, it also knows +its progressive improvement. It is striving to achieve the highest place +among social institutions, and the day may come when it shall obtain it, +for nations will then owe to us their health and life--that is to say, +their earthly happiness. + +The laws by which organic phenomena are regulated, are, we have said, +everlasting; we may also declare that they are general. One of these +laws common to the plant, to the shell, to every species of vertebrata, +reappears in man, whose organization comprises all the functions divided +among the other organic kingdoms. Not only does the organization of man +obey the laws which govern the vital phenomena of other animals; not +only does he possess their organs and functions, but he is a tributary +subject to their diseases. So that the knowledge of the laws affecting +the functions and diseases of those creatures which are placed below him +in the scale of animals ought to be the first foundation of all medical +study. + +These truths are too manifest to be new; they are written and professed +everywhere, and every one amongst us has received general notions of +comparative anatomy and physiology at the beginning of his course of +study. But let us admit that these notions only served to expand the +circle of our knowledge and ideas, and that we seldom or never apply +them to the practice of our art. It would have been very different had +we received at the beginning of our medical novitiate, not merely in +theory and books, but practically and experimentally, precise notions of +anatomy, physiology, and, let me add, of the _pathology of all +animals_. Let us suppose for a moment that the task had been imposed +upon us before entering upon the study of human maladies, to observe the +structure of plants and animals, to submit their tissues to +microscopical examination and chemical analysis; to study experimentally +all their functions and diseases, and acknowledge that had such been the +case, the anatomy, physiology; and pathology of man would have been far +better understood, and that most of the difficulties against which we +now contend in vain in our helplessness, might easily have been +overcome. + +Comparative anatomy and physiology are the first conditions of all +medical instruction of a serious character; there can be no doubt on the +subject, but the evidence being not perhaps so palpable with respect to +comparative pathology, it will not be useless, therefore, to enter into +fuller particulars as to this subject. + +We know not whether any one has ever sought to retrace the first origin +of our diseases in the animal kingdom, but it would undoubtedly be a +study of great scientific interest. As for us, we gladly believe that +man, created to be the sovereign lord of the earth, did not originally +receive the principle of every organic disease with which we see him +affected. It seems to us probable that he was created sound in body and +in mind, but unequal is his vital powers, and in his faculties and +talents, the social functions being various and dissimilar, and subject +to physical and moral infirmities. We think it likely that plants and +animals, from which, in course of time, man's substance is formed, have +transmitted the first causes, the germs of some organic diseases with +which they were themselves affected. We see in this transmission of +animal diseases to man, a connecting link, which appears to us to be a +condition of harmony, order, peace, and happiness among all living +beings. It seems to us that the first injunction of a legislator should +be--_love other animals like yourselves_; for if man had practised this +maxim, he would have logically applied the same to his fellow-creatures; +and no doubt, with such principles to guide them, past generations would +not have bequeathed to us the innumerable calamities we have had to +deplore. + +We think that we receive from animals some of their diseases, because +the fact is palpably evident; thus they have parasitical diseases, such +as favus, tænia, psora, trichinosis, which they transmit to us. They are +likewise smitten with small-pox, typhoid fever, and with typhus; and +under certain given conditions they may transmit them to us. They die of +consumption and cancer, and it is probable that they transfuse into us +through their milk and flesh the germs of these diseases. Finally, we +have our epidemics as they have their epizootics; and here we will limit +our instances of this reciprocation. + +It is certain that the study of these maladies in animals would have +been for us the source of precise knowledge, which, if well understood +and explained, would have often led to their preventive treatment. This +is what has occurred in the case of small-pox; it is what will one day +occur in typhoid fever, in times of epidemic, as will be the case in a +certain number of other general or local diseases. + +In truth, some complaints now looked upon as inherent to the human +species, were originally foreign to it; most parasitical diseases +belong to this class. Thus man has not the _psora_, or itch--the +disease does not properly belong to him; the parasite which engenders it +is not bred in him, it is always transmitted to him by animals. It is +the same with the tænia, or tape-worm, with the trichina, or fine +hair-worm. + +Medical science, instituted on the bases of comparative pathology, would +have made the study of diseases in the brute creation, not the +collateral, but the principal object of its inquiries. It would have +applied itself to the cure of the lower animals; and whilst learning to +cure them, it would have ensured the cure of men's diseases. + +If such be the case, can any one believe that the treatment of diathetic +and hereditary maladies would be, as they still are, insoluble problems; +and that the physician would have the misery of seeing decimated, whilst +he helplessly looks on, a large part of the population, condemned +inevitably to die of consumption and cancer? Would every man smitten +with hydrophobia be irrevocably condemned to death? Assuredly, it would +not be so. + +That the physician should have been reduced to the painful necessity of +confessing his want of means, when medicine could be nothing more than +an art, we admit; but now that science has grown up and come of age, +society has a right to challenge him to do, what in past ages could not +have been expected of him. Briefly, we think that the time is come, by +blending comparative pathology with anatomy and physiology, to construct +one of the bases of the tripod on which medical science will have to +rest. The success which has already been achieved in this direction is a +certain guarantee for those which we may hope for hereafter. + +Such is our deep conviction, and perhaps we have some title to speak out +decidedly on this point, as we have long since exemplified our precepts +by actual proofs. + +Persuaded for many years that comparative pathology afforded to +industrious men a new mine, rich in precious veins for working, we +several times endeavoured to explore this fertile field. But, +unfortunately, our means of action not being consistent with our +sanguine expectations, we were repeatedly compelled to suspend our +pursuits, until at last we found at the Ecole Vétérinaire d'Alfort, the +favourable opportunity and the essential conditions of which we had so +long been in quest. + +Grieved at our helplessness to stay the ravages of pulmonary +consumption, I formed one day the resolution to study that wasteful +complaint in animals in order to discover, or at least to look for, the +required remedy. With that view, I confined in a dark, cold, and damp +cellar a number of animals to practise on: birds of different species, +rabbits, a monkey, a dog, &c. To these animals I dealt out a deficient +quantity of food. The monkey, as might have been expected, was the first +to be affected, since in our climates they all die of consumption. Next, +and for the same reason, it was the parrot's turn; then the chickens and +ducks died; after them the rabbits;--in fine, at the end of fourteen +months, the dog alone survived. All the rest had sunk under consumption, +and exhibited tubercles in different organs--in the lungs or mesentery. + +It was then necessary to have the counter-proof: to place a second set +of animals in the same conditions, to produce the disease again, and +attempt its cure. But the first experiment had been a long one, and I +was forced to relinquish the inquiry, which, moreover, was above my +means at that period. + +On another occasion, it seemed to me strange that we should be obliged +to open the bladder of patients suffering from the stone, or to subject +them to lithotrity, which has also its perils. Nature, I said to myself, +forms calculi by uniting organic elements, by crystallizing them, and by +cementing them with vesical mucus. But would it not be possible to cure +the disease by employing contrary means--dissolving the calculi in the +bladder by means of continued injections, changing the chemical agents +according to the composition of the calculus, and adding thereto the +action of a galvanic current? + +After this, I pursued my inquiry in this direction. I studied for +several months the chemical composition of calculi by examining them in +their dissolved state; and I saw that those in which the alkaline bases +prevailed, being submitted to a diluted solution of tartaric acid, which +would not injure the bladder, crumbled after a time; that the calculi +with excess of acid were also attacked by an alkaline solution; in +fine, that the calculi of oxalate of lime alone seemed to resist the +action of these chemical solutions. But it is well known that they +sometimes defy all lithotrite instruments, and compel us to have +recourse to the knife. + +These preliminary experiments over, it was necessary to come to their +application, and for that purpose to make experiments on some animals. +The canine species, omnivorous like ourselves, was chosen in preference. +Bitches were selected to be practised on; for as their urinary passages +are wider and more flexible, it enabled me to insert in the bladder +fragments of calculi already analysed, which were to serve as the nuclei +to the stones they were intended to develop. + +This second assortment of animals, penned up apart from each other, were +supplied with different modes of sustenance: some of them were put upon +a diet of meat only, others on a farinaceous diet, and a third set on a +mixed course of food. These experiments were being regularly followed +up, when an important and unforeseen event compelled me to desist at the +end of six months. The poor animals were destroyed; but all of them, as +I had anticipated, had generated calculi of various chemical +composition. + +These unfinished inquiries concerning comparative pathology, thus +interrupted in spite of myself, might, had circumstances allowed them to +reach the goal, have authorized us to undertake in man the dissolution +of stone in the bladder. And how would this have been effected? By +seizing the stone between the two ends of the catheter with the double +current, and by injecting a well-sustained series of dissolvents into +the patient, whilst lying at his ease in a recumbent posture. + +Nor is this all. They would likewise, I believe, have thrown some light +on the organic production of calculi, on the lithic diathesis, and the +particular formation of the stone; and led us, in some degree, to their +preventive treatment, which is always superior to the curative remedy. + +On a subsequent occasion, I betook myself to my task under more +favourable conditions. I undertook at Alfort, conjointly with Professor +Delafond, a course of experiments on the cutaneous diseases of animals +in relation to comparative pathology, having already, whilst walking +the hospitals, published a work on the "Entomology and Pathology of +Psora in Man," which had been printed at the expense of the Academy. + +These inquiries and examinations at Alfort were persisted in for five +years, and were considered to have led to very satisfactory results as +regards general pathology. But I have spoken of these labours in the +first part of my book. + +Pardon me, reader, and do not suppose that vanity or any desire to +parade myself has induced me to refer to these experiments. No; my only +object is to show to what results similar studies might lead, if they +were executed on a large scale and on the whole animal kingdom; if, +instead of these partial efforts made under favour, some special and +appropriate medical institution encouraged earnest experimentalists, +supplying them without stint with all necessary resources, and with the +best and completest instruments of observation. + +Will any one deny, that if medical science had been settled on this +foundation fifty years ago--that is to say, since the exact sciences +first began to provide us with the means of investigation, it would now +be so impotent? Epizootias and epidemics would not thus flout us as they +do; the cholera would no longer be an enigma, nor the ox typhus so +incurable. No! a hundred times no! Medical science would not he helpless +and impotent in our day, had our forerunners been more mindful and +provident. + +But, instead of this, the science for which we plead would have done +good work. It would have made and confirmed an infinite variety of +observations on the brute creation; it would have transmitted our +diseases to them as they transmit their diseases to us; it would have +treated and cured these diseases, and every such cure would have been a +new triumph, a new victory for mankind. + +For instance, during an outbreak of cholera, this science would have +been ready and prepared to try different experiments on men and animals; +it would first have communicated the cholera to animals, and then +submitted them to a variety of experimental treatments. This cholera, +which is not an infectious fever, with its regular and assigned periods, +like typhus, and which we are not obliged to suffer to run its course, +but which, on the contrary, is a nervous affection produced by some +poisonous miasma, the toxical effects of which first of all assail the +nervous system and then more particularly the great sympathetic; the +cramps being but the result of a reflective action--_this cholera, we +say, must be curable_, and well-advised experiments would reveal the +remedy we want for it, nor should we have to wait long for the +revelation. + +As for me, I once made a desperate attempt in this direction. It was +during the cholera of 1854. We remarked whilst dissecting subjects, as +is always the case, that the mucous membranes of the stomach and +intestines, which were in a manner paralyzed, had suffered the fluid +parts of the blood to ooze out on the surface. Hence the cause of those +vomitings, and those watery and colourless diarrhoeas which nothing +can stop, so that at a given moment the patients die, poisoned, of +course, but dying more particularly through want of circulation, the +blood being reduced to its solid parts and unable to circulate any +longer. Relying on this fact, and trusting for want of better to the +secondary effects, I strove to restore to the blood its aqueous part, +and, if possible, to re-establish the circulation. + +With this view, I went to the Hôpital de la Charité, provided with all +the requisite instruments. Choleraic patients were being brought there +every hour. The experiments being new, venturesome, and _dangerous_, in +the eyes of the hospital directors, I was only suffered to operate on +the moribund. The first patient, considered to be in a state +sufficiently desperate to be given up to me, was a woman, forty-five +years old. She was literally insensible, and thoroughly cold. I +hesitated for a moment to try the operation under conditions so +unreasonable, so preposterous--almost upon a corpse. The radial arteries +in the arm had ceased to beat, and the heart alone kept up a feeble +circulation at the central parts. At length I opened the vein, from +which not a single drop of blood proceeded, and taking the usual +measures to prevent the air from having access, I gradually and slowly +injected two ounces of alkaline solution, the process of injection +lasting twelve minutes. It was scarcely over before the patient +half-opened her eyelids, and looked about her with astonishment; the +pulse became perceptible for a few moments, and all present thought she +was saved. We put a few questions to her; the patient could not answer +us, but she nodded as much as to say "yes," when asked if she felt +better. But this was all we could do in her case. The circulation +stopped again, the patient relapsed into her state of insensibility and +died two hours after the injection. + +The result obtained in this instance had not answered our expectation. +However, the circulation had for a minute or two resumed its course, and +a flash of reason had once more shown itself. + +I thought the experiment ought to be repeated, and accordingly the next +morning I made another trial. The patient this time was a working +shoemaker, thirty-eight years of age, exactly in the same far-gone, +hopeless state as the patient of the day before. In his case, the inward +commotion caused by the injection was more powerful; twenty minutes +after the injection he was able to see, to understand, to speak, to +raise his head; but this vital recovery was, as in the former case, but +of short continuance, and two hours and a half after the operation the +man expired. + +After these experiments I dissected the two bodies, and then, finding +that their lungs were infiltrated with water, I understood that the +alkaline solution had not been assimilated, that it had stopped in its +passage into the pulmonary parenchyma, to the detriment of the functions +of the hæmatosis. I also understood that the proper injection, instead +of distilled alkaline water, would have been the serum of the blood, +drawn at the very moment from some man or animal. + +The conclusion which I drew from these experiments was that a variety of +operations, made at different stages of the malady, might lead to +beneficial results, especially if we succeeded in transmitting the +cholera to animals, as that would enable us to test a large number of +curative agents and to pursue a methodical course of experimentalization. + +From all I have said, I infer that life, health, and disease, being +subject to the same laws throughout the whole animal kind, it is certain +that the physician should possess precise knowledge as to the +organization, the functions, and diseases of animals. That by proceeding +in this manner, we shall advance from the simple to the complex, from +the plant to the animal, and from the animal to man. That we must of +necessity emerge from the state in which we are now entangled BY FOUNDING +AND ESTABLISHING IN LONDON A COLLEGE OF THE NATURAL AND MEDICAL SCIENCES. +Every medical pupil might spend two years in this college, receiving in +it an experimental and practical training; he would devote himself in it +to the chemical analysis of all bodies, to physiological experiments and +tests, without limit and of every kind. + +Most deeply do I appreciate the many difficulties and obstacles that +would interfere with the execution of such a design. In our civilized +age, nations seem rather bent on seeking out the means of exterminating +each other than of protecting themselves and animals from epidemics and +epizootias. It is believed that every first-rate kingdom now spends from +400 to 500 millions of francs (16 to 20,000,000_l._) annually in +maintaining their land and sea forces, whilst one-half of their +populations are living in misery and ignorance, in disease and +corruption. The time is not come--shall we ever see it?--to employ the +vital powers of the peoples, to better incessantly their social +condition. Perhaps, by reason of its organization, the Government of +this country would not be authorized to devote 100,000_l._ or +200,000_l._ to the establishment of an institution like the medical +college I suggest, notwithstanding its paramount necessity. But England +is in the habit of doing great things independently of the Government. +In default of the ruling powers, then, let me appeal to the national +initiative, for if the spectacle which we are at present witnessing was +not, in the case of England, one of those trials which invigorate a +people by the salutary teachings which they bring; if it did not induce +them to take some energetic resolution by which their interests would be +saved and their power enlarged, it would indeed be a deplorable sign of +the times and make us despair of its future. + +Moreover, to show the urgency of founding a _College of Natural and +Medical Science_, let us add, that in every other country they are +endeavouring to unite this indispensable complement to medical +education. The German universities, the Faculty of Paris, have, for +several years past, incorporated a course of comparative pathology, with +the other series of public lectures. + +It is not a mere Utopia that we propose, but an extension and +improvement, all the parts of which are already prepared. If this +College could be thrown open to-morrow, competent professors would be +ready at the call of duty to indite the programme for this instruction +within twenty-four hours; and as for the professors themselves, there +would be enough to choose among the large body of efficient scholars who +do honour to the country. + +If we have been rightly understood, we desire to see established in +London an institution which would afford an equivalent to what exists in +Paris, at the Museum and Collège de France, where numerous courses of +lectures on anatomy, physiology, physics, and chemistry are given. Only +in London this special college would be formed and organized on such a +scale as to bear away the palm from every previous foundation of the +same kind; it would be an institution unexampled in the world, out of +whose halls would one day come anatomists, physiologists, and +pathologists of the very highest order of excellence.--But organic +matter would not be the sole object of this instruction, for the animal +is something more than matter. Courses of medical history and +philosophy, of really general pathology, would introduce the students to +the grand phenomena of nature, to the great laws which govern the worlds +and the globe; and descending from the heights of science to the +observation of the infinitely minute, they would never forget the +important part of the vital powers, and of that unknown power called at +different times by the names of +pneuma+, _archéc_--_mind_ and _soul_. + +The Regent's Park would, we think, be the proper site for this college, +as the contiguity of the Zoological Gardens would afford continual +opportunities for investigating the diseases of animals. + +Moreover, this college would not trench upon or interfere in any manner +with those medical and veterinary establishments which at present exist; +it would ally itself with, and complete them, nothing more. The +instruction received at this "College of Natural and Medical Science" +would be so useful and necessary, and so attractive withal, that the +sons of the great families would come to it to finish their collegiate +studies, to the great benefit of the country. Other young men, in +considerable numbers, would flock to it from various parts of the world. +The foundation of such an institution would be an epoch in the history +of science, and would give England another claim to the esteem of +nations. + +I conclude, then, with a conviction that a nation which owes to Lord +Bacon, the founder of experimental philosophy, his imperishable book on +the _restoration, the method and teaching of the sciences_; to Harvey, +the circulation; to Priestley, the constitution of chemistry; to +Sydenham, the modern Hippocrates, his treatise on "Practical Medicine"; +to Jenner, vaccination; and to Charles Bell, the discovery of the +sensitive and motor nerves--is a people too great and too enlightened to +retrograde; and that, if the epizootic of ox typhus did find them at +first unready and disarmed, they will in the end convert this disaster +into a new source of greatness and strength. + +Such is the sincere hope which I cherish and the prayer I offer up for +the happiness of a country which, for the future, has become my own. + + + + +APPENDIX. + + +NOTE A. + + BREMEN, August 30. + +The following report, drawn up by two German veterinary surgeons, of a +recent visit to London to examine into the cattle murrain, has been +furnished by the agent of the North German Lloyd's at Nordenhamm:-- + +"On Wednesday, the 9th instant, we, the undersigned, were requested to +be at Nordenhamm, if possible, the following morning. Upon our arrival +we were asked by the agent of the North German Lloyd's, who had +consulted with several of the chief cattle exporters, to undertake a +voyage to London at once in the steamer _Schwan_, in the interest of the +cattle export from the Weser. The object of our mission was, first, to +examine as closely as possible into the epidemic cattle disease raging +in and around London for some time past; then carefully to observe the +treatment of cattle upon the vessel during the voyage, upon arrival, and +at the time of disembarkation; lastly, to use every means in our power +to prevent obstacles being opposed to the continued export of cattle +from these ports to England. + +"Furnished by the agent of the North German Lloyd's with letters of +introduction to cattle dealers in London, and with the necessary funds, +we left Nordenhamm in the steamer _Schwan_, Captain Christensen, at 4 +P.M., on the 10th instant. The vessel carried 347 head of large +cattle, 2 calves, and 260 sheep. Favoured by very fine weather, we +arrived in the Thames at 2 P.M., on the 12th. At the beginning +of the voyage the animals were rather uneasy, trampled a good deal, and +caused considerable motion in the ship; after a time, however, they +became quiet. A sharp, penetrating smell was easily perceptible in the +'tween decks of the ship, which was quickly removed upon a light breeze +springing up, by means of the excellent ventilation and numerous +air-pipes and wind shafts. The animals were several times watered, and +it was easy to see how greatly they were refreshed. The hay in the +racks, on the other hand, was hardly touched. + +"Upon arriving in the port we were introduced by the captain to the two +veterinary surgeons stationed here to inspect the cattle, and witnessed +the rapid disembarkation of the cargo, all of which were thoroughly +healthy, not one being condemned. The cattle, when landed, were +immediately brought to carts standing in readiness and transported to +London, where they are cleansed and then driven into the adjacent +fields. + +"After doing all in our power to attain the object of our journey, we +went back to the port to wait for the _Schwan_, having first thoroughly +cleansed the clothes we had worn during our inspection of the diseased +cattle. The _Schwan_ came in shortly after our arrival, and disembarked +256 head of large cattle, 12 calves and 400 sheep, all in good +condition. Mr. Philipps, the London agent of the North German Lloyd's, +was on the spot, together with several reporters from newspapers, who +wished to see by personal investigation how and in what condition cattle +are brought from the Weser. + +"We re-embarked on the _Schwan_ upon the 19th. The crew were engaged +during the voyage in carefully cleansing the ship. The weather was fine, +and we arrived safely at Nordenhamm upon the 21st. + + (Signed) + + "G. J. RIPPEN, + "Veterinary Surgeon at Seefield. + + "H. FASTING, + "Veterinary Surgeon at Schwey." + + +NOTE B. + +Professor Simonds having had such opportunities of investigating those +diseases as they existed in England and in foreign countries as were +possessed only by a few Englishmen, might be permitted to offer a few +observations. He had been appointed by the Royal Agricultural Societies +of England and Ireland to proceed to the Continent in 1857, when there +was a rumour that the disease which existed among cattle in this country +at the present time was prevailing in Mecklenburg. Consuls sent +despatches that the rinderpest was prevailing largely, and the +Government, as a precautionary measure, closed the ports against the +introduction of cattle from the Baltic to this country. He found, +however, from his observations abroad that since 1817 there had been no +disease of this kind westward of a line between Revel in the Baltic and +the Gulf of Venice, but to the eastward of that line it had existed. He +came up with the affection at the Carpathian mountains, where it was +raging in 1857 just as it is raging in England at the present time. Not +only had it existed there, but it had been carried into the interior of +Russia in the ordinary method of the cattle trade. A person who was in +the habit of purchasing cattle attended a fair and bought a number of +animals, and took them to his own farm, and in the course of ten days +one or two were seized with the disease, and the result was there was a +gradual spread of the evil in that district. It gained ground until the +Government instituted the sanitary police regulations, which, though +they were such as would be considered strange in England, were, he +believed, absolutely necessary for the extirpation of the plague. It was +undoubtedly true that no foreign animals had been seized at our ports or +in the metropolitan market; but it was not necessary for the case they +had in hand to say whether the disease was or was not of foreign +importation. There was this fact before them, that it was not until the +month of June that the disease appeared in England. A certain number of +animals came out of a diseased district. He had documentary evidence +that animals came from Revel and came from the district of Esthonia. He +had before him proof that the disease now in England was raging in that +district. They had proof that shortly after the arrival of those cattle +in England the disease manifested itself here. He admitted there were +difficulties in the way of checking the importation of foreign cattle. +The Government had its eyes open to the matter, and he did not think it +possible for the Government to have done more than they had done or to +have done more quickly what they had been doing. At this moment half the +supply of the metropolitan market came from foreign countries, and he +did not wish to convey any reflection by saying that this disease had +its origin from abroad. He would admit that the animals from Germany and +Hungary were coming in a healthy condition; but he could not admit that +they came from Russia, Poland, or Galicia in so perfect a condition, +because the regulations there were not sufficient to stamp out the +disease. The Government had made an inquiry as to the general health of +cattle on the Continent. They believed France, Belgium, Holland, +Schleswig-Holstein, Oldenburg, and a large part of the Continent that +supplied cattle to this country were free from disease. This went to +show that we had admitted a disease not from where we received our +supplies of meat, but from some other district. Then it must be +associated with the fact that it came into this country when animals +arrived here from an infected district in Russia. Animals from Germany +and Hungary were often shipped and mixed with others from a diseased +district. As regarded the disease being spontaneous, we had been free +from it for twenty years. What was the state of our cowsheds fifty years +ago? Were they not in a more filthy condition than they are now? If, +therefore, the disease had been induced from common causes it would have +been here years and years ago. It was no reflection to say that a great +many cases could be traced directly to the metropolitan market. Take one +case which occurred in Sussex. Certain cattle had been bought in the +metropolitan market and were taken home. In three or four days they were +ill, and presented symptoms of this affection. In a few days more the +cows and calves were dead. In another instance calves were bought in +Chichester Market, where they had been taken from London. The result was +the death of twelve cows and ten calves. The people had other cattle on +the same farm, and not one of them took it. He could say, too, that +persons who had only one animal had lost it by the disease. How had the +disease got into Norfolk and Kent but by the animals which went from the +metropolitan market? He could prove by documentary evidence that it was +so. He could show there was not a single instance where the origin of +the disease could not be traced to the metropolis. It was the most +fearful visitation that had ever been seen in England. They had adopted +a system of compensation in Norfolk, and if by this meeting something +was done to shut out the animals of infected districts, no doubt the +promoters would receive not only the thanks of London, but the country +generally. + +Mr. Gibbins--Now, if the disease came from abroad, and diseased cattle +were shipped on the other side of the sea, no doubt the voyage would +concentrate and aggravate the disease. The Government inspectors +reported, however, that not one instance had been seen of foreign cattle +so diseased, nor had any been seized and destroyed in London or anywhere +else. Whether the disease came from abroad or elsewhere he was not able +to state. Sir George Grey asked him whether he had found any disease +among the foreign cattle that came into the market. He said not one. +They had, no doubt, many instances of the disease amongst the cows that +were ordinarily called milch cows, but that were not milch cows when +they came to market, because one effect of the disease was to deprive +the animal of milk. These were then sent to the market and sold as fat +stock. He could only say they had had no cases, except in cows, whether +they came from the dairies in London or elsewhere. + + +NOTE C. + +M. Dembinski, Professor of Analytical Chemistry and Natural Science, had +also addressed a communication to the Lord Mayor on the subject. The +prevalent Rinderpest, he said, originated in the steppes of Podolia, +from which considerable herds of cattle were exported through the +steppes to Moscow, St. Petersburg, Riga, and Revel, and thence to the +ports of Memel, Königsberg, Dantzic, Hamburg, Kiel, and the Hague. +_Deprived of congenial food and pure water on their transport through +the steppes, and then arriving at marshy lands, the exhausted animals +drank the stagnant water, which, during hot weather, exhaled a +pestiferous malaria, and infected them with a predisposition to the +epidemic in question, which developed itself into a kind of fever on the +voyage to England in a crowded condition._ + + +NOTE D. + + INTERNATIONAL VETERINARY CONGRESS, VIENNA, + August, 1865. + +With regard to the cattle plague, it may be well to state that Austria +has been most unfortunately situated, from the readiness with which +Russian cattle have been admitted into the country at various parts of +the western and southern frontiers. At the opening of the Congress this +difficulty was particularly noted by the Ministerial counsellor, Dr. +Vell, who attended on behalf of the Government, for the purpose of +welcoming the assembly, and giving an assurance that its deliberations +would meet with all the attention they deserved. He specially referred +to the fact that the laws relating to cattle disease prevention had been +entirely revised in 1850, but that the Steppe murrain continued to be +introduced by smuggled stock into the western and southern provinces of +the State. It was therefore necessary to attempt a more effectual +control over the propagation of so disastrous a malady. + +Herr Pabst welcomed the meeting on behalf of the Minister of Trade. He +said that the value of the cattle of the Austrian dominions considerably +exceeded one hundred million pounds sterling (one thousand million +Austrian florins), and that cattle plagues completely put a stop to the +development of that essential branch of agriculture which embraces the +improvement and increase of live stock in a country. He assured the +assembly that all would be done that was possible to improve the +existing state of matters, and that he hoped they would greatly aid the +Government by the discussions which would take place and the conclusions +at which they would arrive. + +I may state, by the way, that an opinion rather generally expressed by +some, and stoutly maintained by others, was that the peculiar +disposition of some of the Austrian subjects, and the feeling existing +in Hungary against State measures, rendered the law, to a great extent, +inoperative. I can, from personal experience, state that although +stringent and most efficient means are used for the suppression of +cattle plagues, and with the best results in Austria proper, there is +great difficulty in carrying out the law in districts where Austrian +rule is at a discount. Indeed this is clearly indicated by the manner in +which the Rinderpest penetrates into Austria, where the laws are similar +to those in the kingdom of Prussia, which is, and has long been, +completely protected from invasions of the disorder. + +At the meeting of the first International Congress, held in Hamburg in +1865, Dr. Röll stated that owing to the length of time to which the +quarantine for Russian cattle extended on the Austrian frontier, herds +of cattle were often smuggled through, and companies had been formed for +the purpose of insurance against seizure by the authorities. The +unlawful traffic was therefore carried on with comparative safety to the +dealers, who cared not what misfortune they brought on a country if only +their personal ends could be served. This question was the first to +occupy the attention of the Congress last week; when a resolution was +proposed to shorten the period of quarantine for cattle from Russia +into any country from twenty-one days to ten. The discussion was keen. +It was stipulated, however, that the quarantine should be carried out +most strictly over all parts of the frontier, without respect to any +breed of cattle or other circumstances which might be brought forward as +exceptional reasons for retaining animals in quarantine. The committee +appointed to prepare a succinct report on the subject included +Professors Unterberger, Seifmann, Werner, Zlamal, Hertwig, Haubner, and +Röll; and the committee decided in favour of the shortened quarantine, +on the following conditions:--First--When the establishment of +quarantine institutions is effected in accordance with the requirements +of trade and the peculiarities of the frontier, special attention must +be paid to the erection of quarantine stables, &c., where there are +facilities for procuring an abundance of fodder and water. Second--The +animals to be kept under efficient veterinary supervision wherever they +have to submit to quarantine. The inspectors must be properly qualified +veterinary surgeons. Third--The use of a brand to indicate that the +animals have been in quarantine. Fourth--The effectual disinfection, by +washing and otherwise, of animals as they leave the quarantine. +Fifth--The introduction of a poll-tax along the eastern frontiers, and +the appointment of proper veterinarians to be on the watch as to the +health of cattle along the frontiers. Sixth--Careful supervision to be +placed over the traffic in cattle wherever it takes place in a country. +Seventh--The punishment to the full extent that the law allows of all +who break the rules relating to quarantine or other means for the +prevention of the cattle plague. + +Professor Hertwig, of Berlin, whose opinion is always listened to with +great respect in veterinary circles, stated his reasons for adopting +these resolutions now, whereas in 1863 he was against shortening the +period of quarantine. He referred chiefly to the importance of not +offering temptations for cattle dealers to evade the law by insisting on +unreasonable restrictions. The feeling of the assembly was greatly in +favour of avoiding vexatious and expensive measures, which might greatly +interfere with the employment of capital in cattle traffic. A small +number of professors, not exceeding eight or nine, held out for a +quarantine of twenty-one days. + +It may be as well to state that quarantine regulations, which have been +regarded as almost useless in the prevention of human disorders, from +the great difficulties in the way of carrying them out efficiently, are +recognised as of great value in controlling the propagation of cattle +plagues. It is possible to control the movement of herds, and the +governments of Central Europe have found it absolutely essential so to +do. Indeed, the ablest medical men who have written against the adoption +of a quarantine system for human small-pox and cholera, such as +Professor Siegmund, of Berlin, acknowledge its value and absolute +requirement with regard to the Rinderpest. A professor from Galicia +argued in favour of controlling the movements of people wherever the +disease appeared, and no fact seems to have been better ascertained than +that of the communication of the Rinderpest from herd to herd by human +beings. Professor Jessen, of Dorpat, states that in Russia the malady +was at one time speedily propagated by the people, who regarded the +destruction of their stock as a visitation of Providence, and who +summoned a priest into their stables to pray with them that the plague +might be stayed. Moving from farm to farm, the malady was by this means +rapidly transmitted. In Hungary, many outbreaks result from people +dressing the carcases and hawking about the meat, which, even where +human beings remain uninjured, is deadly to the cattle whenever the +water with which it is washed is thrown about the yards, or the meat is +hung up near sheds containing living animals. + +The members present at the International Congress spoke in favour of +establishing a fund, apart from the Government grants, for the payment +of diseased or infected animals which have to be slaughtered with a view +to the prevention of the plague. Special precautions were suggested as +to the transmission of articles the product of diseased animals. + +1. Perfectly dried skins, the points of horns cut off, as they often are +for commercial purposes, the salted and dried intestines of cattle, +melted tallow, wools, cowhair, &.c., could be freely allowed to pass +unobserved. + +2. Entire horns, hoofs, &c., which are detached from the soft parts, but +which often contain adhering flesh, &c., should be disinfected with +chloride of lime. + +3. As melted tallow is often conveyed in bags which may be charged with +the poison, those bags should be washed with chloride of lime solution. + +4. Fresh bones, fresh skins, and intestines, unmelted tallow, raw flesh, +and fresh sheepskins, should not be sold whenever the Rinderpest exists +in a district. + +According to all the accounts which reach us, the foreign observations +and resolutions may be of essential service in England. The members of +the Assembly were informed by Mr. Erner of the origin and the progress +of the cattle plague in England, and were deeply interested by the +account given of the imminent danger in which many countries are placed +that purchase breeding stock in the British isles. The theories of +spontaneous origin amuse the learned here not a little, as they justly +think we ought not to be so far behind every nation in the possession of +knowledge regarding the propagation of such a disorder as the steppe +murrain. + + +NOTE E. + +Now, if the disease came from abroad, and diseased cattle were shipped +on the other side of the sea, no doubt the voyage would concentrate and +aggravate the disease. Whether the disease came from abroad or elsewhere +he was not able to state. Sir George Grey asked him whether he had found +any disease among the foreign cattle that came into the market. He had +not one. He could only say they had had no cases, except in cows, +whether they came from the dairies in London or elsewhere. So far as +they knew, not one single bullock or ox had been condemned.--MR. GIBBINS, +_18th August, Meeting at the Mansion House_. + +The very first shed in which the plague must have appeared in London is +a pattern of cleanliness, and the stock was magnificent, as proved by +the animals in a shed to which the disease has not been propagated. +Almost simultaneously the malady broke out in the Essex marshes, and in +every instance we trace a more or less direct contamination by foreign +stock. + + +NOTE F. + + VIENNA, August, 1865. + +On the 28th of August about thirty of the members of the Congress +accepted an invitation to visit the renowned agricultural establishment +at Altenburg, in Hungary. After the visitors had inspected the herds and +other appurtenances of this institution, Professor Maasch, its director, +intimated that the Rinderpest had appeared at Nickolsdorf, about four +German miles from Altenburg. The President of the Congress had known +this fact before the party left Vienna for Hungary; but as he feared +some enthusiasts would first see the plague, and then inspect the +Altenburg herds, he preferred to adopt the stratagem of communicating +the information through Professor Maasch, after the great Agricultural +College of Hungary had been viewed. Nickolsdorf, where the steppe +murrain appeared on the 10th of August, is an exquisitely clean village, +with well-whitewashed buildings and broad roads, constituting the centre +of a thriving agricultural district. Its people are typical Hungarians, +not too anxious to work, and, on the whole, poor; but they are +intelligent, notwithstanding the national proclivity to farm a thousand +acres badly rather than one-fourth the quantity to perfection. Their +wants are not great, and their worldly luxuries, beyond potatoes and +schnaps, are bought with the profits made on large herds of cattle. One +herd only had suffered from the cattle plague when we visited the +village. This herd consisted of 1225 animals, divided into three lots. +The affected portion numbered 450 animals--bullocks intended for work +and slaughter--varying in age from three to seven years. The cows and +heifers had not been smitten. The 450 animals amongst which the disease +appeared were housed in no less than sixteen different sheds in +Nickolsdorf. Out of each of these places sick animals had been taken, +and either slaughtered or permitted to die. We killed four for +dissection on the 29th. Six more had been previously killed, their hides +slacked, and the entire body buried; nine had died, and two we left in +life to be soon slaughtered and disposed of as the others. The district +veterinary surgeon in constant attendance was an extremely active and +intelligent man, who recognised the disease on its first outbreak, and +adopted such measures for separation, destruction, and burial, as +prevented the disease from spreading so rapidly as it has in England. + +The cause of the outbreak was the intermingling of cattle-dealers' stock +with the Nickolsdorf herd; and although the animals which carried it +have not been fully traced, they are believed to have been owned by a +butcher who had purchased them in Comorn, where the malady is raging. +Singular variations have been seen in the symptoms exhibited, especially +when animals are first affected. During the Nickolsdorf outbreak there +has been an invariable incubation of five or six days; then furor or +delirium appears: the bullocks stare, roar, stamp with their feet, are +prepared to attack people who approach them, and seem to be dizzy at +intervals. They shiver, their muscles twitch, the eyes soon begin to +discharge, and the mucus which flows from the mouth foams. The pulse is +at first slower than usual, until all the fever symptoms appear. There +is more constipation than diarrhoea, though, on examination, the +mucous membranes are all found to be affected precisely in the manner so +often observed in England during the present outbreak. The differences +in the symptoms are accounted for by peculiarities of breed, the +condition of stalls, the food the animals have lived on, and similar +circumstances. We may hear more of these Hungarian outbreaks, but the +chances are we shall not witness in any part of Austria the wholesale +devastation now going on in Great Britain.--_International Veterinary +Congress._ + + +NOTE G. + +At present the cowkeepers send off the infected beasts to the market, or +to some slaughter-house, where they might be killed. There was believed +to be great danger in allowing the infected cows to be driven through +the streets. If the good could be separated from the bad animals, and if +the latter could be conveyed to sanitoriums, where the medical men could +operate upon them, then much benefit would result; and then, too, if the +animals died, they would be buried on the spot. All the professors were +agreed in this, that if a compensation fund were raised, and the +cowkeeper were told that he would be remunerated for his loss, he would +at once inform the authorities when the disease made its appearance in +his cowshed. Shed after shed was being now shut up, and men and women +who seemed to be affluent one day were the next reduced to ruin. An +illustration of this would suffice. One day last week a cowkeeper at +Pimlico had 70 or 80 healthy cows. On Wednesday three of them were found +dead. On Thursday 42 of them were sent to the market. Of these 42 three +showed symptoms of the disease, and then the whole of the 42 beasts had +to be slaughtered because of the disease being among the three. The poor +fellow was thus ruined. Last Monday he sent nine more cows to the +market, and these also had to be slaughtered. At present the man was +absolutely out of his mind. Out of his 70 beasts, he had not one left. +Some persons were saying that the disease arose from bad water, bad +ventilation, and bad cowsheds; but in the case of Miss Burdett Coutts, +who had had 40 head of cattle, which were most carefully housed and +attended to--particularly from the moment she heard that the disease was +amongst them--all were gone, with the exception of one cow; so that, +whether it was a want of water or a want of ventilation which in other +cases caused it, this was an instance in which everything was done that +could be done, and yet the plague raged and the mortality +ensued.--MR. GIBBINS, _Meeting at the Mansion House_. + + +NOTE J. + +Yesterday morning Dr. Jarvis, medical officer of St. Matthew's, +Bethnal-green, received information that Mr. Castell, an extensive +purveyor of milk, had lost eighty-four cows during the past week. Other +cowkeepers in this district have also experienced great losses. The +disease has manifested itself with more or less virulence at St. Anne's, +Limehouse; St. John, Hackney: St. Mary-le-Bow, St. George's-in-the-East, +St. John, Wapping; Christ Church, Spitalfields; St. Leonard's, +Shoreditch; St. Mary, Whitechapel; St. Paul's, Shadwell; the hamlet of +Ratcliff, Stoke Newington, Kingsland, and Tottenham. + +Mr. Gibbins, chairman of the Metropolitan Markets Committee, Mr. Rudkin, +a member of the committee, Mr. Tegg, veterinary surgeon to the market, +and Mr. Baldry, clerk to the market, applied to the sitting magistrate +at Clerkenwell Police Court yesterday for summonses against cowkeepers +for sending diseased cows into the market. During the course of the +present week no less than nineteen cows had been seized in the market +and fairs and condemned. The order was asked for under the 8th section +of the recent Order in Council, which recited that it shall not be +lawful to send or bring to any fair or market, or to send or carry by +any railway, or by any ship or vessel coastwise, or to place upon or to +drive along any highway, or the sides thereof, any animal labouring +under disease. The cattle seized had not been examined by a Government +inspector, and no certificate had been given to the owners that they +were fit to be removed. The market authorities wished it to be known +that proceedings would be taken in every case that was brought under +their notice. Mr. Cooke observed that the inspectors had power to seize +and slaughter, or cause to be slaughtered, and to be buried in any +convenient place, any animal labouring under the disease. Had that been +done? Mr. Tegg said that the animals were in some of the cases +slaughtered, and the others would be slaughtered in the course of the +day. The summonses were granted. + +Yesterday, the summonses issued at the instance of Mr. Frederick Thomas +Stanley, a member of the Royal College of Veterinary Surgeons, and one +of the inspectors appointed under the Order in Council, came on for +hearing before Mr. Burcham, magistrate at the Southwark police court. +The summons in the first case was addressed to Thomas Meredith, of the +Flying Horse-yard, Blackman-street, for that the defendant, without the +licence of the said inspector, did unlawfully remove from his premises +some animals labouring under the cattle disease. Mr. Sleigh, instructed +by Mr. Gant, appeared to support the summons; and Mr. W. Edwin for the +defendant. Evidence was given that the defendant had been warned that +the cows were diseased, but that he had removed them notwithstanding. +The further hearing of the case was adjourned, as were also the other +summonses of a like nature. + +In pursuance of powers vested in him by the Manx Legislature, the +governor of the Isle of Man has issued a proclamation prohibiting the +importation of cattle into the island. Tinder the same Act his +Excellency has power to subject all cattle imported into the island to a +five days' quarantine. + + +NOTE K. + +Tracing, as we have done, the sale of infected stock from abroad as far +back as the 19th of June, we find that each week that the disease has +been amongst us a fresh county has been contaminated; and more than that +when we consider that Scotland has not escaped. + + +NOTE L. + +SCOTLAND.--The cattle plague has travelled North to Aberdeenshire, and +has killed a number of animals almost simultaneously on three farms at +many miles distance from one another. The owners of stock in one of the +districts, and the Royal Northern Agricultural Association, are taking, +or resolving to take, sharp and prompt steps to stay the progress of the +disease. The committee of the association having met on Friday, +appointed a committee of inspection, arranged for a public meeting of +persons interested, and favourably entertained the notion of forming a +fund for mutual insurance against the sacrifices and losses which the +extension of the disease might occasion. A meeting of the General +Central Union was also held at Stirling on Friday, and a committee was +appointed to confer on the subject with the directors of the Highland +Society, and report to another meeting to be held next Friday.-- +_Scotsman._ + +The most important communication received to-day is from Scotland. The +malady has undoubtedly broken out near Kelso, on fourteen head of cattle +imported into London and sent north. Twenty-eight animals have been +seized with the disease at Woolwich, and calves from the London market +are said to have taken the malady down to Horsham and Grinstead. + +Information has been received concerning the sale of at least fifty-four +diseased and infected animals in the Metropolitan Cattle Market the 3rd +instant. + + +NOTE M. + +Mr. Charles Panter has, at the request of Earl Granville, drawn up a +statement relative to the health of the cows on a farm hired by his +lordship at Golder's-green, on the Finchley-road. In publishing the +statement, Earl Granville says: "When I left England, a month ago, there +were about 130 milch cows in four sheds. In the two largest and best +managed I found only one cow yesterday (Sept. 4). His Royal Highness the +Duke of Coburg informed me last week that what he believed to be the +same disease visited Coburg last year. No one could trace its origin, +and no medical treatment was successful. Air and water were their only +remedies. Some men had died from eating the meat killed at a particular +stage of the disease. His Royal Highness had seen a horse die in four +hours, killed by flies which came from the carcase of a cow which had +been allowed to remain above ground. The disease disappeared in the +autumn as mysteriously as it had come. I understand that Professor +Simonds is of opinion that the disease mentioned by the Duke of Coburg +is not the same as that from which we are suffering here--that its name +is the Siberian Pest." Mr. Panter's statement is dated Sept. 4, and is +as follows:--"On the 13th of July I purchased five Dutch cows in the +Metropolitan Market, and placed them in quarantine at Child's-hill Farm, +one mile from here. On the 22nd of July one of them showed signs of +debility; diarrhoea followed. Thinking it was only a cold, she was +treated accordingly, but continued to get worse, and died in five days. +Two more were attacked in a similar way, when veterinary advice was +called in, but in five days the whole either died or were slaughtered. +Every precaution was used to prevent the spread of infection here; the +men who attended the sick cattle were not allowed to go among the +healthy ones, and _vice versâ_. But, previous to this, bearing of the +disease in the London cowsheds, I adopted precautionary measures, such +as a liberal use daily of chloride of lime, administered one ounce of +nitre in half a pint of water to each cow, and a small quantity of tar, +and painted their noses with tar. But on the 8th of August, +unfortunately, the disease showed itself here in a fat cow that had been +for ten months in the best built, best drained and ventilated shed. No +new stock had been added for nine weeks. In a few hours four more cows +showed symptoms of it. I immediately had them all removed and +slaughtered, and made a _post-mortem_ examination of them, and found the +windpipe in a state of decomposition, the lungs inflated, the small +intestines red and inflamed, and the meat of a dark yellow colour +outside, and dark red inside, which I think unfit for human food after +the first stage. The disease confined itself to the above shed of +forty-eight cows (which are now all gone) till the 20th of August, when +it broke out in another shed of thirty-five cows, some ten yards from +the former one, and continued its ravages, taking from two to four cows +daily, till they are all gone but two, one of which has not been +attacked; the other, which was a bad case, is cured, and partly come to +her milk again. On the first symptoms I had her separated from the other +stock, and did not treat her for two days, when diarrhoea set in; I +then gave her a bottle of brandy and four ounces of ground ginger in +three quarts of old ale. She lay in a kind of stupor for twelve hours, +when I could see a change in her for the better. I continued to give her +daily four quarts of gruel made with old ale and two ounces of ginger. +In four days she was sufficiently recovered to eat a little hay, &c., +and do without further treatment. In another case the above treatment +failed, and the animal died in three days. In other cases I allowed +anyone to treat them who thought they had a remedy, both professional +men and others. One persevering young veterinary surgeon came up out of +Somersetshire and treated two cases most energetically, but failed in +both; one died in four, and the other in eight days. In other cases +tonics, stimulants, blisters, and setons have been tried, but all +failed. The whole of the eighty-one cows lost were of the English breed; +we have not as yet had any loss out of the other two sheds, consisting +of about half English and half Dutch cows, and standing about forty +yards from the infected shed. It may be interesting for your lordship +to know that I had the shed at Child's-hill Farm immediately cleansed +with disinfectants, and washed with hot lime, &c., and bought twelve +fresh cows and placed them there on the 16th, which are now in perfect +health; and a neighbour situated midway between here and that farm had +twenty-three cows lying in a field; the plague took twenty of them, and +in three weeks he replaced them with new stock, which are still healthy, +he having had them a month. Another neighbour, a mile distant, had a +fine herd of seventy-two cows (English) lying in the fields a fortnight +ago. The plague broke out among them, and now he has only eight left in +health. From my own experience, and from all I can learn, I believe the +disease is atmospheric, and of a typhoid character. The first symptom in +a milking cow is an almost entire loss of milk, then loss of appetite, a +watery discharge from the eyes, nostrils, and mouth, which thickens as +the disease develops itself; rumination ceases, her ears hang down, her +eyes are heavy and sunken, bloody matter is seen in the excrement, great +debility is seen, diarrhoea sets in, and death takes place in from +three to nine days. I have read of iron water being a preventive of the +disease. All the water your cows have drunk comes six miles through +rusty iron pipes." + + +NOTE N. + +THE CATTLE MURRAIN AT HOLLY LODGE.--On the 27th of June an +Alderney bull was purchased at Bushey, near Watford, and placed with the +rest of the herd, then consisting of eleven cows, five sucking calves, +three yearling heifers, and one bull. The bull had been imported from +Alderney for several months. About a month after--namely, on the 29th of +July--a cow in calf was attacked with unusual symptoms. She was +separated from the rest; nourishing drinks were administered; but having +calved, she died forty-eight hours after the first symptoms were +observed. This led to the belief that she died of the disease which then +began to prevail. This cow had been pastured with the others in a field +occasionally used for grazing sheep that were taken to the Metropolitan +Cattle-market, and, if not sold, brought back again until the next +market day; the sheep were separated from the cows by iron hurdles. The +Holly Lodge Estate is partly bounded on the east by the route taken by +drovers with foreign and other cattle to and from the market, some of +which are also occasionally brought back to neighbouring fields. The +high road forms the western boundary within a few yards of the +cattle-sheds and pastures. These facts are stated to show that the +contagion might have been easily communicated to the animals. A few days +later three calves were attacked with cold shivering and twitching of +the muscles. The previous nights having become suddenly and unusually +cold and wet, the symptoms were at first attributed to that cause. +Although these calves had been pastured quite apart from the cow which +first died, the cow had been driven across the field where the calves +lay to the shed in which it died, the calves having been placed in the +next shed, where two of them died on the 6th of August, unmistakeably +of the cattle plague. The third calf was sent to the Royal Veterinary +College, where it also died. By the 9th of August four cows and the bull +were seized with the disease so virulently that it was thought necessary +to kill them after three days' illness. On the 12th a cow and a heifer +were also destroyed, and on the 14th one of the sucking calves died. +Thus, out of a herd of nineteen animals, twelve had died within a +fortnight. The malady had taken so strong and sudden a hold upon them +that no systematic means of remedy could be applied except separation, +warmth, stimulants, and the medicines ordinarily given in cases of cold +and fever. On the 13th of August two more cows were pronounced incurable +by two of the veterinary surgeons who had been called in; but it was +determined, upon further advice, to try a mode of treatment upon them +not hitherto adopted. One drachm of calomel was administered in gruel, +four hours afterwards one pint of castor oil, and three hours later one +quart of yeast. About two quarts of warm porter were added to a gruel of +yeast and oatmeal, and given at intervals. These remedies acted most +efficiently, and in one case gave much encouragement. The next day the +cow began to eat hay, to chew her cud, and to yield a good quantity of +milk. These remedies, together with bi-sulphate of soda, which +invariably produced a return of the milk, and quinine, were then tried +upon four other patients, with varied success. But in the end all these +cows died, not, it is believed, of the cattle murrain, but of exhaustion +occasioned by the activity of the drugs administered to them. This +belief was strengthened by the healthy appearance presented by the +viscera of the first cow thus experimented upon, on its being partially +dissected after death. The remaining cow thus treated is still alive. It +is impossible to avoid believing that had the medical man who kindly +gave his attention to these animals, been better acquainted with the +constitution of the creature, or had those who tended them had any +knowledge of medicine, three of the cows treated in this manner might +and probably would have recovered; and even when the animals succumbed +the consequences were less serious, the virulence of the poison being +expelled--at least it was undiscernible to those who dissected them. +During the fortnight that the murrain was raging, one cow in calf and +one calf remained perfectly healthy, apparently, until both were seized +within a day of each other; these had always been kept separate from the +sick animals, and tended by other men. The calf died, and the cow was +destroyed, in consequence of the symptoms being so violent. In this case +very little calomel was given. As it may be as well to mention all +particulars, it may be stated here that the men who tended the animals +were provided with a dress, and that it was found desirable that a +certain quantity of stimulants--brandy, coffee, and strong soup--should +be given to prevent nausea and other uncomfortable feelings from which +the men suffered. All the directions respecting the burying of the +animals issued by the Privy Council have been strictly complied with; +clothes, &c., have been burnt, chloride of lime (Macdougall's +disinfectant) was used with others to destroy insects and flies, with +abundance of white-washing. The men were recommended to use, as a wash +for the mouth, manganate of potash. The first crop of grass in the field +where the cattle lay before their sickness, and during it, has been +destroyed also; and it is intended to use some disinfectant, such as +charcoal or lime, to spread over the field. Miss B. C. feels so +persuaded that some mode of treatment could be found to alleviate, if +not to save life, that she has determined to employ a medical gentleman, +who kindly offers his services, and to take also the advice of a good +cow or veterinary surgeon, and to try the effects of various remedies in +some of the cowsheds where persons will be glad to let such experiments +be tried; and it is also her intention to ask the Privy Council to allow +one of the Government Inspectors to assist and report upon the cases. It +may not be altogether unimportant to add that the state of the +atmosphere seemed to have some effect upon the health of the animals, as +upon those occasions the symptoms were most severe during the +thunder-storms which then occurred. The milk which returned was found to +be rather watery, and the cream had a peculiar appearance. At first the +pigs declined it, and it was not thought advisable to continue to give +it at all to any animals for about a week. It is now perfectly good. + + +NOTE O. + +Advices from Holland, dated the Hague, Sept. 6, state: "The cattle +disease has now been observed in the parishes of Kethel, Delfshaven, +Moordrecht, Uaardingen, Averschie, Kvalingen, Nieuwerkerk on the Issel +(two hours from Rotterdam), Spykenisse, Schiedam, Herrjansdam, Maasland, +Sommelsdyk, and Zevenhuisen. It has spread most at Kethel, where it +first broke out among a cargo of cattle not admitted into England. In +the other parishes some sixty animals were infected on the 1st inst. The +post-mortem examination of the diseased beasts presents the abnormal +appearances that have been found in the disease elsewhere, _i.e._, +swollen mucous membranes with red spots, peculiar exudations in the +fourth stomach and intestines, &c. The medical commission declares the +malady to be the _typhus contagiosus bovum_ of modern veterinary +surgery, and recommends that infected animals should be treated with +from three to four drachms of muriatic acid, mixed with six ounces of +treacle and decoction of linseed. Decoctions of Peruvian bark and osier +peelings, with sulphuric ether, are also said to be beneficial to weak +animals. The avoidance of all contact of the cattle-tenders with +infected beasts is especially enjoined, and ventilation and cleanliness +of the stalls strongly recommended. Cattle markets and fairs are +suspended until further orders, and extraordinary measures for +disinfection are applied upon steamboats and railways." + + +NOTE P. + +The following document has been received at the Foreign Office from her +Majesty's Agent and Consul-General at Bucharest:-- + +(_Translation from the Official "Monitoral," No. 173, August 8-20, +1865._) + +GENERAL DIRECTION OF THE SANITARY SERVICE. + +From the 1st to the 15th July a typhus epizooty broke out among the +large horned cattle in the districts of Ilfov, Jassy, Bolgrad, Falcin, +Buzeo, and Roman, which still continues, but is on the decrease. The +Direction, in consequence, publishes the above for the information of +those concerned. + + The Director-General, + + (Signed) D. GLUCH. + + Aug. 2-14, 1865. + + +NOTE R. + +August 14. + +THE QUESTION OF INFECTION.--Yesterday afternoon Mr. Alfred +Ebsworth, of 11, Trinity-street, Southwark, the medical officer of +health for the parish of St. Mary, Newington, attended before the +sitting magistrate to make a statement with regard to the condition of +the parish from the influx of diseased cattle, and the manner in which +they were disposed of. Addressing the magistrate (Mr. Burnham) Mr. +Ebsworth said that on that morning he, in his capacity of medical +officer of health for the parish of St. Mary, Newington, received an +order to attend professionally a man who was seriously ill in +Kent-street, within the parish. While paying the visit to the patient +his attention had been drawn to the condition of a slaughter-house on +the other side of the street, where it was reported to him there were +fifteen cows which had been ordered by the Government officer to be +destroyed at the Bricklayers' Arms Station, and then to be buried. The +animals were accordingly destroyed by the men in the employ of Mr. +George Nicholls, the proprietor of the yard in question; and from Mr. +Nicholls he had learned that, instead of the carcases of the animals +being buried, they were carted through the parish of St. George's to +Mitcham, where they were boiled down, and brought back through the +parish of St. Mary, Newington, in the shape of cats'-meat. He (Mr. +Ebsworth) felt it his duty to come before the magistrate with this +complaint, especially when the cattle plague was so prevalent. He had a +right to inquire upon what grounds the carcases had not been disposed of +on the spot where they had been slaughtered, instead of being carted +through the parish he represented, in a way calculated to spread the +infection. He could not but regard this as a most iniquitous proceeding, +and he attended with a view to prevent a repetition of the practice. Mr. +Frederick T. Stanley presented himself, and said that he was a member of +the Royal College of Veterinary Surgeons. He had been appointed an +inspector of cattle under the orders issued by the Privy Council. Within +the district there were no means of burying the carcases of the diseased +and condemned animals, and in the instance referred to they could not +have been buried in the cowshed. It was impossible to bury the carcases +in the London districts, and hence they were sent to the knacker's yard, +where it was supposed they would be disposed of. Mr. Ebsworth: And +that, your worship, is what I complain of. Mr. Burcham: You think that +the practice to which you have called my attention is calculated to +propagate the extension of the disease. Mr. Stanley declared that the +skins were disinfected under his especial orders. Mr. Burcham remarked +that the animals had been taken to the slaughter-house, not for the +purpose of being killed and buried, but that their skins should be taken +off and disinfected. Why should they have been taken to Mitcham? Mr. +Stanley stated that the disease could not be communicated from a dead +animal, and it was conveyed only by inoculation, or through the breath +of a living animal upon the dead body of a diseased ox. Mr. Burcham: I +do not agree with you in that opinion. I believe that infection may be +conveyed by a dead animal. Mr. Ebsworth said that such was his opinion, +and, having regard to 28,000 patients in the parish, he had felt it his +bounden duty to come forward to make this complaint. He thought such +things ought not to occur. Mr. Burcham was of the same opinion, and that +such a commodity ought not to be allowed to be conveyed through the +public streets in open carts. Just before the magistrate was about to +rise, Mr. Stanley introduced to his worship Professor Simonds, and a +long colloquy (in private) ensued between them. At its close Professor +Simonds retired, and Mr. Burcham said: I wish to state that I wanted to +be satisfied that everything was done by Mr. Stanley that could be done +under the circumstances by which he was surrounded, in the midst of +great difficulty. I have had an interview with Professor Simonds, and he +informs me that there are the greatest difficulties, if not +impossibilities, in finding any places near London in which the dead +carcases of diseased animals can be buried. In the case now before me +these animals were slaughtered at the Bricklayers' Arms Station, and +were then taken to the slaughter-house in Kent-street, under the notion +that the owner of the slaughter-house had the means of boiling them +down. It appears that he had no such apparatus, and hence he found it +necessary to send the carcases to Mitcham, the nearest place at which he +believed the carcases could be buried and disposed of, and the +neighbourhood thereby disinfected. Professor Simonds is perfectly sure +that this meat when boiled down cannot by any probability cause the +infection to spread. It was possible, but not probable, that infection +might be introduced by the carcases of the diseased animals on their way +to the place where they had to be boiled down; but it appears to me, +from what I have just heard, that every precaution has been taken to +prevent such an occurrence. It seems that the authorities cannot find a +place within a reasonable distance in which the carcases can be buried, +and, therefore, they are obliged to have recourse to boiling them down, +as the only alternative. It is right that I should add that the conduct +of Mr. Stanley, the inspector, has been quite in conformity with the +directions he has received, not only under the Orders in Council, but +also sanctioned in my presence to-day by Professor Simonds. I trust that +this statement will remove from the mind of Mr. Stanley any unfavourable +impression he may have entertained; and I will only add my opinion, that +the diseased cattle ought to be removed through these populous +districts in closed and not in open carts. The conversation then closed, +and at an unusually late hour the court adjourned. + +DISEASED MEAT.--At the Thames Police Court yesterday Henry +Frost, an old man, was charged with having allowed to be deposited on +the premises occupied by him in the rear of the house, No. 13, +Sidney-street, Stepney, four quarters of beef prepared for sale and +intended for the food of man, but which was unfit for human food. Frost +carried on the business of a greengrocer. He asserted that he let the +place to other men, who were the actual offenders. It was intimated that +the vestry had no disposition to press for a heavy penalty. Mr. Paget +fined the prisoner 40s. At Clerkenwell, Mr. Tegg, inspector at the +Metropolitan Cattle Market for the City authorities applied to Mr. +D'Eyncourt for an order to destroy a quantity of diseased meat which he +purposed seizing. Mr. D'Eyncourt said the meat must be actually seized +and condemned upon evidence before he could make the order. In the +matter of the seizure of 32 quarters of beef, weighing about 3000 lbs., +which was found on the premises of a knacker in Pleasant-grove, +Belle-isle, Mr. D'Eyncourt dismissed an application made against the +defendant under the Nuisances Removal Act. The defence set up was that +the meat was recognised as bad and diseased by the killer as soon as the +animals were slaughtered. + + +NOTE S. + +The Orders in Council seemed only to complicate the matter, and how +effectually to combat the evil was a most difficult question. Some said +the grand remedy was the knife, and others suggested that the diseased +animals should be sent to a sanatorium. To destroy the diseased cattle +was impossible, except the owner of them or the inspector went round and +obtained an order from a magistrate for their destruction. The last +meeting was adjourned, among other purposes, in order that the committee +might take the opinion of the law officers upon the subject. It so +happened, however, that most of the law officers of the Corporation were +at present out of town. Fortunately the Common Serjeant was found, and +he gave an opinion which confirmed the committee in their view that they +had no power to kill, and no power to do anything except in the matter +of isolation. Then the committee passed a resolution that another +committee ought to be formed to raise the necessary funds for +compensating the cattle-owners, and to see that those funds were +properly applied, for the money was only intended to apply to the cattle +plague, and was not meant to go in the shape of compensation for +pleuro-pneumonia, or for the foot diseases. In other words, they were +now legislating for the cattle plague or Rinderpest only. He resided at +Dulwich, and he found that in the villages adjoining there were many +cows, and never in his life had he seen finer cows. Not one of them had +been affected by the disease. There was a cowkeeper at Peckham who had +200 cows, and all of them were in the most healthy state. At Brixton +Hill a man had 30 cows in the same excellent condition. At Dulwich +nearly all the cows were diseased, but there the shed and other +accommodation was exceedingly bad. In parts of Peckham Rye some of the +cowkeepers had lost their cattle, but there again the places were badly +ventilated, and the cows were badly cared for. He believed that the +disease might be prevented by the use of proper precautions on the part +of those who had the greatest interest in keeping their cows in a +healthy state. He believed, too, that this question affected the whole +of the metropolitan district quite as much as it did the City itself. +There were no fewer than 106 head of diseased cattle lately seized; but, +as he said before, they could not be killed without an order from a +magistrate, and a magistrate would naturally feel a difficulty in +issuing an order to kill so many as 106 head. It was necessary, under +such circumstances, that a deputation should wait upon the Home +Secretary and ask him to provide a remedy, and tell the authorities what +they were to do at such a crisis. If, as it now appeared, the inspectors +and the markets' committee had been slaughtering beasts without +authority, who was to pay the costs should proceedings against them be +commenced? Professor Simonds seemed to think that next session a bill of +indemnity would be introduced, and certainly something of this kind was +rendered necessary, for cattle were now coming here which were consigned +to A., B., and C., and then the owners could not be found, and without +the consent of the owners the diseased beasts could not be killed. The +next subject in the report had reference to slaughter-houses. As there +were no places at present to which cattle in an incipient stage of the +disease could be removed from the sheds in which they were placed along +with untainted cattle, it was now proposed that slaughter-houses should +be established in London for their reception. Then came the question, +how were the beasts to be removed from the sheds to the +slaughter-houses? It was the opinion of many that they ought to be +removed in vans, and not driven through the streets; but, however that +might be, slaughter-houses should be erected in the metropolis where the +tainted animals might be killed. Then came the question, how was an +animal to be dealt with when first stricken with the disease? It was +suggested that hospitals or sanatoriums should be provided, to which the +beasts should be sent. But this was a matter of great importance, to +which the attention of the committee to be appointed and that of the +medical men would have to be directed. If the plague went on it would +affect all classes, rich and poor alike, and instead of meat being as +now at a reasonable rate, it would go up 4_d._ or 6_d._ per pound; but +he had hopes that the disease might be checked, particularly as +Professors Simonds and Gamgee had been more successful in the treatment +of it than they had previously been. + + +NOTE T. + +August 31. + +DEPUTATION TO THE HOME OFFICE.--Yesterday afternoon the Lord +Mayor proceeded from the Mansion House to the Home Office, and had an +interview with Mr. Waddington on the subject of the cattle plague, and +the desirability of establishing hospitals or sanatoriums within the +metropolitan districts for the reception and medical treatment of +diseased cattle. His lordship was accompanied on the occasion by the +following deputation from the Markets and Cattle Plague Committees:--Mr. +Gibbins (Chairman of the Markets Committee), Mr. Webber, Mr. Gower, Mr. +Brewster, Mr. Rudkin, and Dr. Jarvis (the Medical Officer of Health for +Bethnal-green). Sir George Grey having left London for Falloden. + +The Lord Mayor introduced the deputation to Mr. Waddington, and in doing +so, said that their object was to obtain the sanction of Government to +the establishment of hospitals or sanatoriums within the metropolitan +districts, to which diseased cattle could be conveyed from the cowsheds +in order that they might there receive medical treatment, and be, if +possible, restored to health. He observed that similar establishments +had been formed at Edinburgh and other large towns, and that they had +been found to work most satisfactorily, not only in separating the +diseased cattle from those which were non-diseased, but in affording +facilities to the medical profession to exercise their skill and +knowledge under circumstances more favourable to a fair trial of both +than they could expect to find in crowded cowsheds, many of which were +in a filthy condition and badly ventilated. He pointed out the progress +the plague had made, and was still making, in the metropolis, and how +its effects upon the high price of meat and milk were affecting all +classes of the community. The difficulties, he said, of adequately +meeting the necessities of the case were at present very great, and some +of these consisted in the alleged illegality of slaughtering diseased +animals without an order from a magistrate, and also the illegality of +removing those diseased from the cowsheds to the hospitals, supposing +the latter to exist. But he hoped the Government, who had no doubt well +considered a subject of such vast importance, would speedily do away +with those difficulties, and render the fullest aid to the Markets' +Committee and Metropolitan Cattle Plague Committee, who were unceasingly +devoting their time and attention to mitigate, and, if possible, put an +end to the evil. At present, however, the object of the deputation was +limited to that of obtaining the sanction of the Government to the +establishment of the hospitals or sanatoriums. This was an object which +had not only received the general approval of the two committees +mentioned, but also of the medical profession, and he might add, what it +was by no means unimportant to bear in mind, that the cowkeepers +themselves and the salesmen of the Cattle Market were also in favour of +it. + +Mr. Gibbins and the several members of the deputation corroborated what +had fallen from the Lord Mayor, and strongly advocated the necessity of +having the hospitals speedily established. + +Mr. Rudkin called the attention of Mr. Waddington to the fact that the +day before there were fourteen diseased cows seized at the +slaughter-house of the Cattle Market, which had been sent there from the +cowsheds of the metropolis. He argued that this in itself was a proof +that the Order in Council, as at present carried out, was insufficient +to prevent diseased cows from being sent from the cowsheds by their +owners to be slaughtered for human food. + +Mr. Waddington, who listened very attentively to the whole of the +statements, said he would take an early opportunity of communicating +with Sir George Grey upon the subject. In the first instance, however, +he wished the deputation to forward to him their views in writing, and +these also would be transmitted to the Home Secretary. + +The deputation promised to comply with the suggestion, and thanked Mr. +Waddington for the courtesy with which he had received and the patience +with which he had listened to them. + +YORKSHIRE.--The plague has extended to this district. The cases +reported, however, are extremely few, and precautions are being taken +which it is hoped may stop the further progress of the disease. On +Tuesday a meeting of the Yorkshire Medical Veterinary Society was held +at Leeds, and the question was discussed in all its bearings. It was +stated that four cases had occurred in Leeds, and the disease has also +appeared in the Skyrack division of the Riding. The general result of +the discussion was, that members of the society were recommended, when +diseased cattle were submitted, not to order them to be killed, but to +place them in a sanatorium for medicinal treatment; the wholesale +destruction of the animals being regarded as a blot upon the profession. + + +NOTE V. + +Indeed, information has reached us of the disease existing in +Dumfriesshire, but there is some doubt on this point. So long as we hear +of infected, or probably infected, cattle being disseminated in large +numbers from the great markets of the country, we must have the +propagation of the malady. For the welfare of this country, it is deeply +to be regretted that our Government cannot deal with this question as +Continental authorities do. _I regret to say some of our neighbours +laugh at our expense._ They see us helpless owing to the wretched state +of our laws on the subject, and they are not a little amused at the +theories of spontaneous development of the disease which some still +advocate. The French Emperor has sent over Professor Bouley, who is +still in this country, and who telegraphed on his first arrival, about +ten days ago, that the ports of France should be instantly closed to +British cattle. This has been done, and we may depend upon it the French +people will not suffer as we now must.--GAMGEE, _Lettre du 24 Août_. + + +NOTE Y. + +August 16. + +MORE SEIZURES OF DISEASED MEAT.--Yesterday Mr. Paget, in the +course of the proceedings at the Thames Police Court, was informed that +there was a large quantity of meat in a van in the police-yard +adjoining, which had been seized that day by Mr. J. Stevens, the +sanitary inspector of Mile-end Old Town, and which was described as +unfit for human food. The inspector stated, that in consequence of +having been informed that there was a quantity of diseased meat at the +shop of Mr. Frost, butcher, Sydney-street, Mile-end Old Town, he went +there that morning, and found four quarters of beef (two fore and two +hind quarters) which were from a diseased beast. He made a seizure of +them, and heard that the animal had been sent by a person of the name of +Stephens, a cowkeeper in business on Bow-common. The meat was in a very +nasty state, and totally unfit for human food. (Mr. Paget went into the +police-yard to examine the meat, which was in a very shocking state.) +Dr. Freeman, Medical Officer of Health of the Hamlet of Mile-end Old +Town, stated that his attention was called to the state of the meat by +the sanitary inspector. He examined it, and gave his opinion that it +should be destroyed, as it was not only in a diseased condition, but he +believed that it had died from some disease. Mr. Paget: Can you state +the nature of the disease which caused its death?--Witness: I cannot. +Most likely it was the prevailing epidemic; and if it were eaten it +would be very injurious. Mr. Paget, after hearing the evidence, ordered +that the meat should be immediately destroyed, when the inspector took +the van with its contents to a knacker's yard to see the order carried +into effect. + + +NOTE Z. + +NEFARIOUS ATTEMPT TO SPREAD THE PLAGUE.--Yesterday Mr. Gifford, +Sanitary Inspector to the parish of Paddington, asked (at Marylebone +Police Court) for the magistrate's advice under the following +circumstances:--Applicant said that, in consequence of information +received, he yesterday went to a cowshed situate on the Maryland Farm, +Harrow-road. He found the door fastened. On looking through one of the +chinks, he saw a cow which apparently was in the worst stage of the now +prevailing disease, and his opinion was verified after he had burst open +the door and examined the animal. He subsequently ascertained that the +diseased cow had been brought some distance by a man who was at feud +with the owner of the Maryland Farm, and surreptitiously placed amongst +the healthy cattle. This was the first case where the disease had shown +itself in the parish of Paddington. Mr. Yardley referred the applicant +to the Order in Council, dated the 24th of July, 1865, under which he +thought inspectors of nuisances had power to act summarily. + + +THE END. + + + LONDON: + SAVILL AND EDWARDS, PRINTERS, CHANDOS STREET, + COVENT GARDEN. + + + + + +-----------------------------------------------+ + | Transcriber's Note: | + | | + | Inconsistent hyphenation and spelling in the | + | original document have been preserved. | + | | + | Greek words are transliterated and marked | + | +like so+ | + | | + | Typographical errors corrected in the text: | + | | + | Page 62 Ge11e changed to Gellé | + | Page 67 Bruneleschi changed to Brunelleschi | + | Page 142 Röol changed to Röll | + | Page 175 charboneux changed to charbonneux | + | Page 253 eat changed to ate | + | Page 354 lairs changed to fairs | + | Page 377 Boulay changed to Bouley | + +-----------------------------------------------+ + + + + + +End of the Project Gutenberg EBook of On the cattle plague: or, Contagious +typhus in horned cattle. 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Its history, origin, description, and treatment, by Honoré Bourguignon + +This eBook is for the use of anyone anywhere at no cost and with +almost no restrictions whatsoever. You may copy it, give it away or +re-use it under the terms of the Project Gutenberg License included +with this eBook or online at www.gutenberg.org + + +Title: On the cattle plague: or, Contagious typhus in horned cattle. Its history, origin, description, and treatment + +Author: Honoré Bourguignon + +Release Date: June 22, 2011 [EBook #36496] + +Language: English + +Character set encoding: ISO-8859-1 + +*** START OF THIS PROJECT GUTENBERG EBOOK ON THE CATTLE PLAGUE *** + + + + +Produced by Barbara Kosker, Bryan Ness and the Online +Distributed Proofreading Team at https://www.pgdp.net + + + + + + +</pre> + + +<br /> +<br /> +<br /> +<br /> + +<h1> ON THE CATTLE PLAGUE:</h1> + + <h4>OR,</h4> + +<h2>Contagious Typhus in Horned Cattle.</h2> + +<br /> +<br /> +<h3>ITS HISTORY, ORIGIN, DESCRIPTION, AND TREATMENT.</h3> +<br /> +<br /> +<br /> +<br /> + +<h4> BY</h4> + +<h2>H. BOURGUIGNON,</h2> + +<h4> Doctor of the Faculté de Paris, Fellow of the Société de + Médecine de Paris; Laureate of the Institute of France, Member of the + Legion of Honour, etc.</h4> +<br /> +<br /> +<br /> +<br /> + +<p class="cen"> "Scribo nec ficta, nee picta, sed quæ ratio,<br /> + sensus et experientia docent."</p> +<br /> +<br /> +<br /> +<br /> + +<h4> PHILADELPHIA:<br /> + J. B. LIPPINCOTT & CO.<br /> + LONDON: J CHURCHILL & SONS.<br /> + 1869.</h4> +<br /> +<br /> +<br /> +<br /> + +<p class="cen">TO<br /> +<br /> +MISS BURDETT COUTTS.</p> +<br /> +<br /> + + +<p class="smcap"> +<span style="margin-left: 1em;">Madam,</span><br /> +</p> + +<p>The numerous services which you have rendered, and the interest you have +shown in the calamitous epizootic which at this moment decimates the +noble herds of England, have prompted me to dedicate the following pages +to you, satisfied that I am only giving public expression to the homage +felt for you by many of your fellow-countrymen.</p> + +<p>I have the honour to be, Madam,</p> + +<p class="right"> +<span style="padding-right: 7em;">With respect, your obedient servant,</span><br /> +<br /> +<span style="padding-right: 5em;">H. BOURGUIGNON.</span> +</p> +<br /> +<br /> +<br /> +<br /> + +<hr /><span class='pagenum'><a name="Page_vii" id="Page_vii">[Pg vii]</a></span> +<br /> +<h2>PREFACE.</h2> +<br /> + +<p>Nations, during the successive phases of their evolution on the globe, +in which they advance from a state of infancy and barbarism to one of +virility and civilization, from civilization to decadence or senility; +and from decadence to their final extinction, are liable to numberless +calamities.</p> + +<p>These calamities are produced by moral causes, and are then called +social Revolutions; and in other instances from physical causes, and +then they are termed Cataclysms, Epidemics, or Epizootics.</p> + +<p>In these crises, the initiative and devotion of individuals, the public +administration, and the application of knowledge acquired in the Arts +and Sciences, afford collectively an infallible criterion for<span class='pagenum'><a name="Page_viii" id="Page_viii">[Pg viii]</a></span> +ascertaining the position which a nation occupies in the scale of +civilization, and the value of its religious, social, and political +institutions.</p> + +<p>Calamities always leave behind them disasters and victims, but they +bequeath also a precious legacy. Nations which are called upon for fresh +and progressive efforts, find in the experience they have gained a new +source of strength and means of future greatness. I am convinced that +this will be the case with England; though, helpless for the moment, and +unable to stay the Cattle Plague which now ravages her entire extent, +she will in future be found better prepared to resist the inroads of +such a direful enemy.</p> + +<p>No branch of human knowledge has been more rudely tested during the +present epizootic than medical science. Many persons have been astounded +at its helplessness; but if they had reflected at what a distance +medicine has to follow in the wake of the exact sciences by which it is +furnished with instruments for <span class='pagenum'><a name="Page_ix" id="Page_ix">[Pg ix]</a></span>prosecuting its researches,—that +organic chemistry progresses but slowly,—that the Cattle Plague was +entirely unknown to the present generation of medical men in +England,—and that the means for its scientific and practical study have +been therefore wholly wanting, they would have been less surprised to +find that it is as difficult to cure the Cattle Plague as it, is to cure +phthisis, cancer, hydrophobia, and the cholera, against which medicine +but too often is of little avail.</p> + +<p>In times of great national calamity it behoves every one to contribute +in proportion to his talents, fortune, or abilities, to alleviate the +effects of the common misfortune. The poor man's mite, and the honest +intention of the most insignificant, when added to the budget of common +efforts, have their relative value; and it is for these reasons that I +have published the following monograph on the Cattle Plague.</p> + +<p>If it assists in any way to the extinction of the present epizootic, or +if it serve to point <span class='pagenum'><a name="Page_x" id="Page_x">[Pg x]</a></span>out the necessity of combining the study of +comparative pathology with that of medicine, I shall feel that I have +contributed something which may favour my claim to be enrolled among the +citizens of England.</p> + +<p>This book, as may easily be seen, was originally written in my native +language. A few kind and obliging friends—more particularly Mr. Taylor +Sinnett, Drs. Clapton and Gervis, of St. Thomas's Hospital, and Mr. +Berridge, of the British Museum—have rendered me the greatest +assistance in the translation. Without the guidance of such competent +auxiliaries I could not have performed my arduous task.</p> + +<p>I therefore beg to return to those gentlemen, and to all those who have +assisted me on this occasion, my sincerest and most grateful thanks.</p> + +<p class="right"> +<span style="padding-right: 1em;">H. B.</span></p> +<br /> +<br /> +<br /><span class='pagenum'><a name="Page_xi" id="Page_xi">[Pg xi]</a></span> +<br /> + +<hr /> +<br /> +<h2>CONTENTS.</h2> + +<div class="centered"> +<table border="0" width="70%" cellpadding="2" cellspacing="0" summary="Table of Contents"> + <tr> + <td class="tdl" width="10%"> </td> + <td class="tdl" width="12%"> </td> + <td class="tdl" width="68%"> </td> + <td class="tdr" width="10%" style="font-size: 80%;">PAGE</td> + </tr> + <tr> + <td class="tdl" colspan="3">Introduction</td> + <td class="tdr"><a href="#Page_1">1</a></td> + </tr> + <tr> + <td class="tdc" colspan="4">FIRST PART.</td> + </tr> + <tr> + <td class="tdlh" colspan="3">The History of the Contagious Typhus of the Ox, from + the remotest Times down to the Present Day</td> + <td class="tdrb"><a href="#Page_5">5</a></td> + </tr> + <tr> + <td class="tdc" colspan="4">SECOND PART.</td> + </tr> + <tr> + <td class="tdlh" colspan="3"><span class="smcap">Chapter I.</span>—On Typhus Disease in + general, and the Typhus which affects the Ox in particular</td> + <td class="tdr"><a href="#Page_72">72</a></td> + </tr> + <tr> + <td class="tdl" colspan="3"><span class="smcap">Chapter II.</span>—The Origin and Causes + of the Ox-Typhus</td> + <td class="tdr"><a href="#Page_84">84</a></td> + </tr> + <tr> + <td class="tdlh" colspan="3"><span class="smcap">Chapter III.</span>—Description of the + Contagious Typhus of the Ox; its Symptoms, Course, Progress, &c.</td> + <td class="tdr"><a href="#Page_140">140</a></td> + </tr> + <tr> + <td class="tdl"> </td> + <td class="tdl">1.</td> + <td class="tdl">Symptomatic Characteristics</td> + <td class="tdr"><a href="#Page_141">141</a></td> + </tr> + <tr> + <td class="tdl"> </td> + <td class="tdl">2.</td> + <td class="tdl">Lesions found in the Bodies after Death</td> + <td class="tdr"><a href="#Page_163">163</a></td> + </tr> + <tr> + <td class="tdl"> </td> + <td class="tdlt">3.</td> + <td class="tdlh">Diagnosis—Prognosis—Use of the Flesh of Animals—Danger of + direct Absorption</td> + <td class="tdrb"><a href="#Page_173">173</a></td> + </tr> + <tr> + <td class="tdl"> </td> + <td class="tdlt">4.</td> + <td class="tdl">General Considerations on the Typhus, and Recapitulation of the Symptoms</td> + <td class="tdrb"><a href="#Page_191">191</a></td> + </tr> + <tr> + <td class="tdlh" colspan="3"><span class='pagenum'><a name="Page_xii" id="Page_xii">[Pg xii]</a></span> + <span class="smcap">Chapter IV.</span>—Treatment of the Ox-Typhus</td> + <td class="tdr"><a href="#Page_206">206</a></td> + </tr> + <tr> + <td class="tdl"> </td> + <td class="tdlt">1 & 2.</td> + <td class="tdlh">Means and Measures to be employed to resist the Causes of Contagious Typhus + of the Bovine Species</td> + <td class="tdrb"><a href="#Page_208">208</a></td> + </tr> + <tr> + <td class="tdl"> </td> + <td class="tdl">3.</td> + <td class="tdl">Curative Medication</td> + <td class="tdr"><a href="#Page_237">237</a></td> + </tr> + <tr> + <td class="tdl"> </td> + <td class="tdlt">4.</td> + <td class="tdlh">Hygienic Measures to be taken against the Extension of the + Contagion—Acts and Orders concerning sanitary Police Regulations</td> + <td class="tdrb"><a href="#Page_257">257</a></td> + </tr> + <tr> + <td class="tdc" colspan="4">THIRD PART.</td> + </tr> + <tr> + <td class="tdl" colspan="3">To Farmers and Graziers</td> + <td class="tdr"><a href="#Page_281">281</a></td> + </tr> + <tr> + <td class="tdc" colspan="4">FOURTH PART.</td> + </tr> + <tr> + <td class="tdlh" colspan="3">Suggestions on the Improvements to be effected in + the Study of Medical Science, in order that we + may be in a Condition to confront Disease generally, + and Epizootic and Epidemic Diseases in particular</td> + <td class="tdrb"><a href="#Page_311">311</a></td> + </tr> + <tr> + <td class="tdc" colspan="4">APPENDIX.</td> + </tr> + <tr> + <td class="tdl" colspan="3">Various Documents</td> + <td class="tdr"><a href="#Page_337">337</a></td> + </tr> +</table> +</div> +<br /> +<br /> +<br /><span class='pagenum'><a name="Page_1" id="Page_1">[Pg 1]</a></span> +<br /> + +<hr /> +<br /> +<h2>INTRODUCTION.</h2> +<br /> + +<p>Everyone is talking of the <span class="smcap">Cattle Plague</span>! But why should we +borrow this sinister and gloomy denomination from the middle ages and +from the people's vocabulary? Is this, then, an unknown and incurable +disease? Is this the first time that it has made its appearance on the +soil of Great Britain? To judge by the manner in which the diffusion of +this complaint has been met, accounted for, explained, and discussed, +one might imagine it was so; and yet the mere observation of its causes, +its symptoms, and its signs and effects on the bodies of the diseased +animals, besides a few references to the medical library, would easily +have testified that nature did not wait until the second half of the +19th century to generate a new distemper. No! Nothing new has appeared +for a long time in the worlds of space. The cosmic phenomena pursue +their perpetual course, and the organic <span class='pagenum'><a name="Page_2" id="Page_2">[Pg 2]</a></span>phenomena, <i>à fortiori</i>, do the +same. Life, throughout the whole range of the animal kingdom, whatever +may be its changes and fluctuations, submits to the fixed and invariable +laws which hold dominion over health and disease. Our presumption and +ignorance alone can account for the astonishment we manifest, not only +when we witness great general calamities, but even when we look upon +those simple morbid derangements which organic matter, both animal and +vegetable, is continually undergoing on the globe, in the natural +progress of destruction and dissolution.</p> + +<p>The habit we most of us have contracted of confining our observations to +the phenomena which strike our eyes, instead of fixing them on the +general causes by which these phenomena have been produced; the +forgetfulness of some, in others the want of acquaintance with general +and comparative pathology, have in this instance led many conscientious +inquirers to misapprehend both the nature and the treatment of the +cattle complaint. It is in vain that we have subdivided and classed +medical science—in vain that we have arbitrarily instituted a +veterinary medicine and a <span class='pagenum'><a name="Page_3" id="Page_3">[Pg 3]</a></span>human medicine; nature, in her acts, has no +such subtleties. With nature, organic matter is organic matter, life is +life; and although it may be true that both organic matter and life +become more complex, and continue to rise in perfection till they reach +man, it is quite as true that the laws of pathology and physiology are +the same in all, and that it is just as difficult to cure the typhus of +the ox as that of man. As, therefore, it is because we overlooked these +fundamental truths, that the outbreak of the cattle distemper found us +unprepared, we must treat the subject with all the gravity which is its +due.</p> + +<p>Let it not, however, be feared that the special fact of the <i>so-called</i> +Cattle Plague will be lost sight of amidst a crowd of scientific +generalities. No; collateral reflections, seemingly foreign to the main +argument, will concur to elucidate it; and all these rays of light will +converge to a common centre, reflecting, we flatter ourselves, some +evident facts and practical truths.</p> + +<p>This work on the contagious typhus of the ox is divided into four +principal parts.</p> + +<p>The first part contains the history of this <span class='pagenum'><a name="Page_4" id="Page_4">[Pg 4]</a></span>typhus from the remotest +times down to the present day. It is divided into several sections.</p> + +<p>The second part, which gives the description of the disease, is +subdivided into four chapters.</p> + +<p>The first chapter treats of general typhus, in order that a perfect +understanding may be arrived at as to the name and definition of the +particular distemper which affects the ox.</p> + +<p>The second relates to the causes and origin of the disease.</p> + +<p>The third treats of its symptoms, its progress, &c.</p> + +<p>The fourth contains its mode of treatment.</p> + +<p>The third part gives some plain instructions for the benefit of farmers, +cattle-dealers, and dairymen.</p> + +<p>The fourth part gives a development of the scientific means and +safeguards to be adopted, in order that this country shall never relapse +into that state of helpless panic to which a want of preparation exposed +it when the present epizootia began its ravages.</p> +<br /> +<br /> +<br /><span class='pagenum'><a name="Page_5" id="Page_5">[Pg 5]</a></span> +<br /> + +<hr /> +<br /> +<h2>FIRST PART.</h2> + +<div class="blockquot"><p class="hang" style="margin-left: 2em;"><i>The History of the Contagious Typhus of the Ox, from the +remotest times down to the present day.</i></p></div> +<br /> + +<p class="cen">I.</p> + +<p>General, local, and particular causes of destruction are constantly +reacting on organized creatures, and these causes account for those +<i>epiphytic</i> diseases which infest plants, the <i>epizootic</i> diseases which +spread mortality among the brute creation, and the <i>epidemic</i>, which +strike and are fatal to the human species. Thus it is that we +particularize at present, in the vegetable kingdom, the disease which +has attacked the vines, olive-trees, and potatoes; in the animal +kingdom, the silkworm sickness, and the cholera, and the typhoid fever +of cattle: so that we may safely say, that one or other of these +diseases is always, at a given <span class='pagenum'><a name="Page_6" id="Page_6">[Pg 6]</a></span>moment, raging in some part of the globe +among some species of animal, either birds, pigs, horses, sheep, horned +cattle, or, in fine, attacks man himself.</p> + +<p>When, however, the peccant invasion falls only on the vegetables and +animals situated at our antipodes, we seldom hear of the ravages it +commits; and when we do, forgetful of the affinity which links together +all the organic beings on the earth and their mutual dependence, nothing +can exceed the indifference we show to these calamities. Then, when the +danger threatens us nearer home, or when the evil has invaded us, we +have recourse to quarantine as the grand preservative to shield us. But +this preservative remedy is most frequently deceptive—a mere illusion; +for the real plague, typhus and cholera, borne along by the winds of +heaven, pass over the longest distances and the highest obstacles, and +baffle all our calculations; teaching us, by their successive returns, +that we shall continually be exposed to their destructive havoc so long +as we neglect to eradicate the evil at its original source, that is, in +those countries from which it emanates.</p> + +<p><span class='pagenum'><a name="Page_7" id="Page_7">[Pg 7]</a></span>And this is the place to observe, that the cholera morbus threatens to +keep a permanent footing in the English possessions of India, because +the public works, by means of which the great rivers used to be confined +to their beds, have not of late been repaired and kept in good order in +those countries; owing to which neglect, their waters overflow the +plains, leaving, when they subside, those pestilential deposits which +afford a perpetual incubation to the cholera.</p> + +<p>We are induced to dwell thus on the general causes of these diseases, +because the sick plants, on which dumb animals feed, and the sick +animals, on which man himself feeds, have a continual relation of cause +and effect; and we shall have to refer to this subject and give it +weight, when we come to speak of the treatment of these diseases.</p> + +<p>It is an important fact, which deserves our most pointed attention and +consideration, that the vital resistance inherent in the animal frame to +withstand the attacks of these contagious diseases, is very far from +being the same throughout the whole kind. Man, in this respect, is the +most favoured and best <span class='pagenum'><a name="Page_8" id="Page_8">[Pg 8]</a></span>fortified; he is able, without much +degenerating, to inhabit any latitude, to go with a sort of impunity, if +his calling require him to do so, amidst the most pestilential +emanations, and to continue for hours inhaling their baneful fumes. We +could quote many striking examples of this resisting power in man. But +there is one which we have recently witnessed, and which all can +appreciate. We refer to the slaughter-house of the great Metropolitan +Market. Here we saw, in lumps and fragments, every variety of corrupt +<i>detritus</i> of animals which had been seized with the contagious typhus; +we saw the animals, too, being felled and slaughtered and dissected, in +a high temperature which rendered the air so poisonous that we could +hardly breathe it; yet amidst all this infection the workmen employed to +move and handle these revolting wrecks appeared indifferent to the +scene, and quite in their usual health. No living animal besides man +could stand such a trial; no other could breathe for hours, and day +after day, like these workmen, an atmosphere so charged with decomposing +impurities.</p> + +<p>We say, therefore, that man may expose <span class='pagenum'><a name="Page_9" id="Page_9">[Pg 9]</a></span>himself, with less danger to his +life than any other animal, to those pernicious causes which produce and +develop contagious diseases. Next to him, with respect to this power of +vital resistance, come the omnivorous animals, then the carnivorous, and +last of all, the herbivorous, in which this faculty is very feeble +indeed.</p> + +<p>This prime consideration, to be fully understood and appreciated by +unscientific readers, would require explanations beyond the scope of +this work. Let us, however, for the present establish the fact, that +herbivorous animals, such as sheep and horned cattle, offer but a very +weak resistance to the causes which generate infectious and epizootic +diseases, and let us do our best to prove it by demonstration; for if +this truth be once admitted, we shall therefrom deduce that it is the +duty of man constantly to surround these frail and delicate creatures +with special care and attention, if he wishes to prevent their being +decimated from time to time, and if he would likewise avoid the +consequent injuries to himself—the loss of health and money accruing +from this deterioration.</p> + +<p><span class='pagenum'><a name="Page_10" id="Page_10">[Pg 10]</a></span>So long as the herbivorous or grass-eating animal is properly fed; so +long as he browses on fat pastures; so long as his blood retains those +physiological elements which are the prime condition of health, he can, +and does, resist the causes of most contagious maladies. But if a hot +summer and a long continuance of dry weather chance to curtail, in +temperate zones, the usual abundance of his fodder, then comes the fatal +change: the blood is impoverished, the secretions are debilitated, a +strange languor runs through the system, the vital resistance is +unnerved, and he becomes an easy prey to those noxious influences which +were encountered before without injury whilst his provision was +abundant.</p> + +<p>This is a fundamental matter. We therefore beg leave to support and +justify our argument by borrowing some additional evidence from prior +labours of ours, accomplished at the Ecole d'Alfort, near Paris, +conjointly with Professor Delafond, whose name has so often been cited +in the public journals in connexion with the cattle plague.</p> + +<p>All vegetables and animals; with the exception of <i>adult</i> men, whenever +their health <span class='pagenum'><a name="Page_11" id="Page_11">[Pg 11]</a></span>declines from any cause (but more particularly from +paucity of food), spontaneously generate microscopic parasites, or very +minute insects, the germs of which are inherent in their system. A flock +of fleecy animals, wasted by deficient food in dry and parched meadows, +becomes attacked in due time by a parasitical cutaneous disease, known +as the <i>itch</i>, which is enough, if not checked, to destroy the whole. +Now, all that is required is to remove this flock to a more fertile +soil, where there is plenty to feed them, and the disease will disappear +of itself without any treatment. Deficiency of food destroys the health +of animals, and abundance of food overcomes disease in them.</p> + +<p>A sheep affected by this parasitical disease may, without any fear, be +placed in a flock of healthy sheep, for he will not propagate the +distemper; but if instead of being sound and healthy, the flock is in a +weak declining state, this contaminated animal will diffuse the disease +with frightful rapidity, and may cause their entire destruction. These +facts may seem startling, but we are only speaking after the +incontestable authority of experiments.</p> + +<p><span class='pagenum'><a name="Page_12" id="Page_12">[Pg 12]</a></span>We selected six healthy sheep, which we kept well supplied with +provisions; we covered these healthy sheep with parasites (acari). On +every one of these sound, well-fed sheep, the microscopic animalculæ +died off without generating the cutaneous disease; for the blood, the +humours, and the skin of sound and healthy sheep constitute a soil +unfavourable to the propagation of these parasites, and actually starve +them to death.</p> + +<p>After this first experiment, we subjected these six sheep to a deficient +diet; they grew lean, their blood was impoverished, and then all we had +to do was to lay upon them not thousands and thousands of these +parasites—as we had done in the first instance—but one solitary female +in a state of fecundity; and the parasitical distemper unfolded itself +so fiercely as to cause the death of three of these sheep on which the +test was allowed to run its course; whilst the other three sheep, having +been restored in time to a recoverable condition just as they were about +to drop off, were thoroughly cured, without any special treatment, by +the sole influence of good food and ordinary hygienic attention.</p> + +<p><span class='pagenum'><a name="Page_13" id="Page_13">[Pg 13]</a></span>Other tests, similar to these experiments, were applied to dogs, horses, +and horned cattle. A lean and scraggy dog, covered with parasites and +eruptions, with eyes running foul humour, a dog which could neither run +nor stand, and which was reduced to the last stage of wasting marasmus, +was rescued from the jaws of death and thoroughly cured without special +treatment, by the sole influence of a rich restorative diet. This dog +afterwards became a fine hunting hound, beautiful in shape, and +admirable for his sportive attributes.</p> + +<p>These experiments having been submitted to the judgment of the Académie +des Sciences in Paris, were honoured with its approval, and the reports +concerning them were printed at the Academy's expense, and crowned at +the competitive examination.</p> + +<p>The vital resistance of horned cattle is so feeble, that those animals +which are periodically exhibited in the north of London, though +certainly chosen from among the most healthy and robust, could not herd +together in large numbers for the space of a month in the Agricultural +Hall at Islington, without sinking under infectious and contagious +<span class='pagenum'><a name="Page_14" id="Page_14">[Pg 14]</a></span>diseases—almost one and all. Under the conditions in which we see them +in that Show, a single month would be sufficient to produce almost their +complete destruction; for even a single week, which is the usual +duration of their confinement, affects them so much as to render a large +proportion of them unhealthy.</p> + +<p>Every one knows how apt cavalry horses are to sicken and die off during +a campaign. Every one has heard of the fearful ravages amongst the +horses of the Allied armies during the Crimean war, when many companies +were dismounted owing to this mortality.</p> + +<p>Let us now transport ourselves in thought into the middle of those +immense steppes where vast and innumerable herds of herbivorous animals +are being bred for our supply, and consider what will be the effects on +their health and life if they should be afflicted with a scarcity of +forage, in consequence of this long dry summer.</p> + +<p>It is unnecessary to say that there exist in Russia, in Hungary, in +Australia, in North and South America, and in many other parts of the +globe, large tracts of country which are still uninhabited, whose +uncultivated soil <span class='pagenum'><a name="Page_15" id="Page_15">[Pg 15]</a></span>supplies with food great numbers of sheep and cattle. +These spacious tracts, known as moorlands or steppes, particularly +abound in Russia, on the banks of the Wolga, the Don, the Dnieper; in +Hungary, on the banks of the Danube; and also in South America, in the +republics of Venezuela, New Granada, Columbia, &c.</p> + +<p>Now, in hot and rainy seasons these steppes teem with rich and luxuriant +verdure; the plants growing up in the marshes are prolific and abundant, +and even those parts of the wild moors which produce nothing but heath +are capable of feeding and fattening flocks and herds.</p> + +<p>Under conditions so auspicious as these, animals may still suffer, but +in what way? By excess of food, or repletion. They are in general robust +and healthy, and thus fortified they inhale without detriment the +deleterious gases of oxygen with carbon, carburetted hydrogen and the +like, exhaled by the plants which grow out of the swampy soils. Thus +protected, too, they are proof against the fluctuations of the seasons, +and against every injury which threatens them; and their strong and +sound <span class='pagenum'><a name="Page_16" id="Page_16">[Pg 16]</a></span>condition enables them to sustain the fatigues of their long and +arduous journeys, and to supply the rich countries of the West with +their flesh, fleece, and hides.</p> + +<p>When the seasons have thus conveyed a due proportion of heat, water, and +electricity to the elements of the soil, both plants and animals conduce +to the comfort and health of man, and fulfil his expectations. But the +laws of nature are involved in mystery. Good and evil go hand in +hand—death and life travel close together—and a few years of +prosperous harvests are almost invariably followed by blight, +barrenness, and scarcity. Most men think only of the present time, and +this imprudence and want of foresight prevent farmers and great cattle +proprietors from collecting and holding in reserve the requisite stores +of sustenance to supply their sheep and oxen during these barren +seasons. Sickness then breaks out, and these helpless creatures perish +in vast numbers, to the detriment of their owners' best interests.</p> + +<p>And truly, when continual rains cause the rivers to overflow, when the +plains are drenched and soaked, or when a burning sun scorches <span class='pagenum'><a name="Page_17" id="Page_17">[Pg 17]</a></span>the +ground, herbivorous animals wander in vain from field to field in quest +of sustenance to restore their strength, or of pure and healthy water to +slake their thirst; their vital resistance dwindles away, deleterious +gases poison and bewilder them, their blood is debased, and as Ovid +says,</p> + +<p class="cen"> +<span style="margin-left: 1em;">"Corpora fœda jacent, vitiantur odoribus herbæ."</span><br /> +</p> + +<p>And since these mild and harmless animals, which seem to have been +created merely to clothe us, and to nourish us with their milk and +flesh, have not been endowed by nature either with the intelligence, or +the activity, or the cunning, or the invention, or the skill bestowed on +the omnivorous and carnivorous species, hard is their fate under the +pressing needs of hunger. Peaceful creatures, they browse in vain on +deleterious plants on a sterile soil; their external and internal +teguments now afford a favourable seat for the propagation of +parasites—for the <i>parasitogenia</i>; and soon after a general <i>adynamia</i>, +or relaxation of the fibres, delivers them up without resistance to the +morbific elements of the infectious diseases to which they are <span class='pagenum'><a name="Page_18" id="Page_18">[Pg 18]</a></span>exposed, +where the languishing, the sick, and the rotting are herded together, +and they are carried off by hecatombs by this wasteful and devouring +typhus.</p> +<br /> + +<p class="cen">II.</p> + +<p>We may readily conclude, from these general observations on infectious +and contagious diseases, that they must have existed in all former ages; +and if in our present advanced state of civilization they are so +destructive, we may be sure that in those remote periods they must have +been, both as regards man as well as the brute creation, the cause of +general extermination, in whatever parts of the earth they prevailed. +And indeed, whenever we refer to ancient or modern history, we are +continually struck with the analogy which exists between the epidemic +diseases signalized by the general name of <span class="smcap">Plague</span>, and which +decimated all the living beings, and those which more recently, and at +the present moment, have startled the world by their fatal effects on +men and animals.</p> + +<p>Moreover, we cannot too often repeat the fact—in order that those +documents relating to <span class='pagenum'><a name="Page_19" id="Page_19">[Pg 19]</a></span>the past which contain useful instruction may be +examined and searched into—that the physiological and pathological laws +which rule and determine the phenomena of organic matter, whether in +health or sickness, were, like the laws of chemistry, electricity, and +astronomy, originally established at the time of creation, and that +matter submits with passive obedience to the laws of transformation and +transubstantiation, which are the absolute condition of life. These are +the eternal laws of which a synthesis so admirable is furnished by the +Gospel, in this short injunction, "<i>Take, eat, this is my body; drink, +this is my blood</i>."</p> + +<p>Now, if man, who is the sovereign master of this matter, did not take +care to regulate and modify it for his own benefit and the benefit of +all living creatures on whom his own life depends, as well as his wealth +and happiness; if he did not seek thereby continually to diminish the +sum of evil, and to extend the sum of good which it is his mission to +increase, he would violate these laws, which are inherent in matter, and +which have existed for his use since the creation of the world.</p> + +<p><span class='pagenum'><a name="Page_20" id="Page_20">[Pg 20]</a></span>We must likewise believe that those <span class="smcap">Plagues</span> which are spoken of +in the Bible, those which Homer alludes to, that which is related by +Plutarch, and which succeeded the general drought in 753 before Christ; +those mentioned by Titus Livius, Virgil, Ovid, and other Latin authors, +the most virulent of which plagues raged in the years 310, 212, and 178 +of the Foundation of Rome, resembled the epidemics or plagues which are +witnessed in our own day.</p> + +<p>The plague of 212 swept away all the inhabitants of Sicily, cattle as +well as men; that of 178 destroyed all the priests, who sought in vain +for victims free from the contagion, to offer them up as sacrifices to +the offended Gods.</p> + +<p>Cecilius Severus gives a most striking description of a pestilential +disease which, in 376 <span class="smcap">A.D.</span>, swept away all the cattle in +Europe. Judging from his account of that scourge, we may fairly believe +that the distemper he has described was identically the same as the one +which has just broken out in England. "A universal distaste, sudden +dejection, vertigoes, spasmodic tension in the limbs, <i>a painful</i> +<span class='pagenum'><a name="Page_21" id="Page_21">[Pg 21]</a></span><i>swelling of the lower belly</i>, violent affections of the nerves, sudden +death—everything shows the presence of a pestilential ferment, which +irritates the solids, infects and vitiates the fluids, which is the +cause of the putrefaction of the humours, manifested by the swelling of +the lower belly, which in that case depends on a putrid fermentation so +as to disengage air."</p> + +<p>A piece of iron, representing the sign of the Cross, was heated in the +fire, and when red-hot was applied to the forehead of the sick animals; +and this remedy was looked upon at that time as the most effectual they +could apply.</p> + +<p>Grégoire de Tours makes mention of an epidemic, the result of a long dry +summer, which, in 592, was very fatal in its havoc, sparing no living +creature whatever.</p> + +<p>André Duchesne, in his "History of England," speaks of an epidemic +which, in 1316, during the reign of Edward II., owed its origin, on the +contrary, to a long season of rains.</p> + +<p>The celebrated physicians Ramazzini and Lancisi relate that in 1711, an +ox which had been imported from Hungary, that constant <span class='pagenum'><a name="Page_22" id="Page_22">[Pg 22]</a></span>focus of typhus, +displayed the most deadly form of the cattle disease, in the Venetian +territory, although no alteration in the air or waters had been observed +in Italy, and the seasons had been regular and the pastures abundant. +The contagion spread into Piedmont, where it carried of 70,000 head of +cattle; thence it extended to France and Holland, each of which +countries lost 200,000 of these animals. The trade in hides introduced +the distemper into England, where it proved no less fatal. It was the +same in the other countries of Europe.</p> + +<p>In this disease, the intestines of the affected cattle were, as in the +present epizootia, inflamed, and strewed over with livid spots and +ulcerations, and the blood, though apparently fluid in the body of the +animal, <i>coagulated directly after it had issued from the vein</i>.</p> + +<p>Herment thence concludes, that this epizootia is nothing more than an +inflammation of the blood. Lancisi advised his contemporaries to put to +death without pity every animal which was affected or seemed to be +affected with the disease; and it was in <span class='pagenum'><a name="Page_23" id="Page_23">[Pg 23]</a></span>England that this spirited +resolve was first acted upon.</p> + +<p>The three counties of Middlesex, Essex, and Surrey arrested the course +of this contagion in less than three months, by adopting this measure; +whilst in the rest of the stricken counties of Great Britain, and +likewise in Holland, where this decisive course was not taken at all, +the disease prevailed among the cattle for several years. Since that +time, it has been insisted on by some authors, that the barbarous +process of general extermination offers the most effectual remedy which, +in our present state of ignorance and improvidence, we could have +recourse to, in order to check the diffusion and the duration of this +fell disease.</p> + +<p>The learned Goelicke describes an epizootia which was witnessed in 1730, +at Frankfort-on-the-Oder. His narrative, written with a masterly hand, +might very properly be applied to the disease which we are now +considering; and the treatment recommended by this earnest and vigilant +observer is so wisely deduced from the symptoms, that even in the +present day we might take that treatment as a model.</p> + +<p><span class='pagenum'><a name="Page_24" id="Page_24">[Pg 24]</a></span>We could have borrowed much more largely from this source of +biographical researches had we not deemed that these quotations would be +sufficient for the purpose we had in view in this work. But from these +authorities we think it may justly be concluded, that infectious and +contagious diseases among horned cattle have frequently appeared from +the remotest times down to the middle of the eighteenth century.</p> + +<p>All these attacks of epizootia were a frequent and severe cause of +suffering and misery among animals and men; but the ravages which they +left behind them were of slight importance each time, if we compare them +with those attending the epizootia which towards the year 1746 affected +the animal kingdom. This dreadful scourge lasted ten years, and swept +away nearly the whole race of horned cattle throughout Europe. It was +closely studied and thoroughly understood in its causes, its symptoms, +and its treatment by the scientific authors of that day, and those +writers, more judicious than we, did not designate the malady by the +title of <span class="smcap">Plague</span>. This particular visitation deserves to fix our +attention in an <span class='pagenum'><a name="Page_25" id="Page_25">[Pg 25]</a></span>especial manner, not only on account of its striking +resemblance to the disease which now makes us all so anxious, but +because it induced two English physicians, Malcolm Flemming and Peter +Layard, to write on this disease two accounts or statements which are +equal, if not superior, to all the volumes which have since appeared on +the subject of the Cattle Disease. There is no help for it, and our +pride must bend itself to the acknowledgment: these two men, our seniors +by a century, were men of quite another stamp. Their expositions, +enriched with quotations from the Greek and Latin authors, abounding in +facts, ingenious insights and inferences, are far superior in merit to +the multitude of voluminous works which have been written and published +since then. It would be easy to prove that these two sagacious inquirers +far better understood than we have done the real nature of this cattle +disease, and that we must be grateful to them for first opening the way +which all of us must take in order to discover the preventive and +curative means of which we are still ignorant.</p> + +<p>Let us observe, in passing, that these two <span class='pagenum'><a name="Page_26" id="Page_26">[Pg 26]</a></span>physicians, who appear to +have been scarcely known, enlightened by the effects of the inoculation +of small-pox, then practised from man to man, appear to have first +conceived the idea, now practised in Russia, of preventing the +propagation of the contagious cattle disease by means of inoculation; +and we may raise the interest of this remark by reminding the reader +that their experiments to inoculate cattle were made in 1757, eight +years after the very year which gave birth to the future inoculation of +man with animal virus by the celebrated Jenner. By this it would appear +that the twofold honour of applying the method of inoculation as both +preventive and curative means in respect of contagion in cattle, and as +the preventive means by the variola of the cow to resist the ravages of +the small-pox in man, is the indisputable claim of English +physicians.<a name="FNanchor_A_1" id="FNanchor_A_1"></a><a href="#Footnote_A_1" class="fnanchor">[A]</a></p> +<span class='pagenum'><a name="Page_27" id="Page_27">[Pg 27]</a></span> +<br /> + +<p class="cen"><span class='pagenum'><a name="Page_28" id="Page_28">[Pg 28]</a></span>III.</p> + +<p>Very little is known of the origin or first outbreak of the epizootia +which produced such fearful ravages in the middle of the eighteenth +century. Some suppose that it first appeared in Tartary, where it +occasioned a disorder twice as extensive in its pernicious effects as +any similar distemper which had been known up to that time. Thence it +passed into Russia, from which it spread on one side into Poland, +Livonia, Prussia, Pomerania, and Holland, and from that country into +England; on the other side towards the East, it invaded the Turkish +Empire, Bohemia, Hungary, Dalmatia, Austria, Moravia, Styria, the Gulf +of Venice, Italy, Spain, Portugal, France, the banks of the Rhine, and +Denmark.</p> + +<p>But another opinion has assigned Bohemia as the source from which this +destructive epizootia took its rise, and its supporters allege that +during the siege of Prague the cattle feeding in its plains had been +deprived of their usual fodder by the continual <i>razzias</i> of the French +to supply their own cavalry.</p> + +<p>Be this as it may, this virulent cattle <span class='pagenum'><a name="Page_29" id="Page_29">[Pg 29]</a></span>disease having at length +assumed the proportions of a public calamity, the several governments +were obliged to take it into serious consideration, and the medical +faculties and most celebrated physicians began to make it the subject of +their studies and reports. In France, therefore, the professors of the +faculty of Paris and Montpellier, suspending every other pursuit, +devoted their most assiduous care and attention to dumb animals.</p> + +<p>Sauvages, the Dean of the Faculty at Montpellier, drew up a most +philosophical and learned account of the prevailing disease, in which, +like Stahl, he forgot probably for a moment the part which, in the +progress of distempers, he ascribes to the soul.</p> + +<p>The professors of Paris, very famous in their day, but who, having left +behind them no works so valuable as the "Nosologia" of Sauvages, are now +completely forgotten, likewise addressed the result of their inquiries +and lucubrations to the King.</p> + +<p>Doctor Leclerc was sent into Holland, whence he brought back a Memorial, +which was a reflex of the opinions he found current in Denmark, and +which has been transmitted <span class='pagenum'><a name="Page_30" id="Page_30">[Pg 30]</a></span>to us in the <i>Memorials of the Royal Society +of Science at Copenhagen</i>.</p> + +<p>It is evident from the reflections found in the writings of Malcolm +Flemming, Layard, and other competent observers, that this formidable +epizootia was in its character identical with the one described by +Ramazzini and Lancisi in 1711; and we feel warranted in saying, after +having examined every work of any importance which has treated of that +visitation, that it resembles the disease now prevailing among cattle, +in its march, in its symptoms, and in its gravity. We believe that these +three visitations constitute but one and the same malady, occurring at +three different periods. This appears to us a most important fact, for +if such be the case, the tentative treatment of that time deserves our +most particular attention. Consequently, a few retrospective glances may +perhaps be permitted us, in considering the subject of cattle disease.</p> + +<p>The medical professors (including several English physicians), who +observed and described the epizootia of 1745, divided the same into +three periods.</p> + +<p><span class='pagenum'><a name="Page_31" id="Page_31">[Pg 31]</a></span>The duration of the disease, when it passed through all its phases up to +the death of the affected animal, consisting of from ten to twelve days, +they usually ascribed to each of these periods or stages an average +continuance of three or four days.</p> + +<p>1<i>st Period.</i>—After a few days of latent incubation, which the observer +could not suspect, the sick animal betrayed signs of the morbid state +which was about to declare itself, by his careless feeding, by drooping +his head, and by exhibiting the deepest dejection of spirits in his +attitude and look. Rumination, already imperfect, soon ceased +altogether, the appetite failed, the horns, ears, and hoofs were cold, +the hair grew stiff, the tongue and mucus looked white; the eyes were +tearful and fixed, the hearing obtuse, whilst, in the cows, the supply +of milk diminished. In cases of unusual gravity, transient shiverings +testified to a serious disturbance in all the animal functions. These +shiverings were followed by a violent fever, the blood became inflamed, +the breath hot, the respiration hurried and sometimes attended with +slight coughing; when, if too violent a repercussion was transmitted to +<span class='pagenum'><a name="Page_32" id="Page_32">[Pg 32]</a></span>the nervous centres, the pressure on the vertebral line became +intolerable, and the animal, seized with vertigo, and almost delirious +with pain, would fall during this first period, as if struck by +lightning.</p> + +<p>The same phenomena are sometimes observed in the typhoid fever of man, +which offers moreover some analogy with the contagious typhus of the ox; +but as the ox and the horse have likewise the real typhus fever, they +may some day supply us with the preventive virus for that fever, in the +same manner as the cow now supplies us with the preventive virus for the +small-pox.</p> + +<p><i>2nd Period.</i>—In most cases the disease pursued its course with greater +or less regularity; the sick animal experienced gnawing pains or +twitchings, and spasmodic shootings in the limbs, apparently attended +with pain. His thirst was insatiable, but he had no appetite, the +functions of the bladder and intestines were impeded, then diarrhœa +supervened, accompanied with dry, fetid, and sometimes bloody excreta. +Thick viscid mucosities dripped from the nostrils, mouth, and eyes. The +dorsal regions and the loins were <span class='pagenum'><a name="Page_33" id="Page_33">[Pg 33]</a></span>constantly aching, headache and +sleeplessness were permanent. The animal continued either standing or +lying down, and if he wanted to rest, he could not bend himself +gradually, but would fall like an inert mass to the ground.</p> + +<p><i>3rd Period.</i>—Diarrhœa was continual, becoming more fetid every day, +the wasting of flesh made rapid strides; the cellular tissue beneath the +hide was filled with gas along the vertebral channels and under the +abdomen; the nostrils were stopped up with mucosities, the animal could +only breathe through the mouth, puffing and blowing aloud as he drew in +the air; and at last pustular eruptions showed themselves on various +parts; but as this depurating crisis was insufficient, the poor beast, +in this final period of the attack, fell a sacrifice to it between the +seventh and twelfth day. If he chanced to be lying down his agony was +slow, but if standing, he would sink upon himself, and expire at once.</p> + +<p>In this dreadful epizootia, very few of the smitten cattle survived—not +more than four or five in a hundred; and in these favourable cases, the +symptoms presented certain signs and critical phenomena of a happy omen. +In <span class='pagenum'><a name="Page_34" id="Page_34">[Pg 34]</a></span>these rare exceptions, the pulse did not exceed seventy, the +beatings of the heart were always perceptible, the patient did not +refuse to drink, the continuous fever exhibited no aggravation at night, +pustular eruptions and tumours appeared on the dewlap and the fore +limbs, and the epidermis over the mouth and nostrils peeled off about +the twelfth day.</p> + +<p>When dissected, the bodies offered to view the following alterations, +the same having already been observed by Frascator during the prevalence +of the epizootia in 1514, and by Lancisi and Ramazzini during that which +was so fatal in 1711. The mucous glands of the mouth were livid, and +occasionally excoriated; the bronchial tubes were obstructed with +mucosities; the lungs, besides being partially congested, were sometimes +emphysematous, that is, inflated with compressed air. Of the four +stomachs, the rumen was full of food, the reticulum, the omasum, and the +abomasum exhibited purple or livid spots, according to their place. The +thin intestine and the thick intestine showed either a general +injection, scattered livid spots, or ulcerations, according as the fever +had worn the exanthematous or typhoid form; <span class='pagenum'><a name="Page_35" id="Page_35">[Pg 35]</a></span>for the mucous membrane of +the digestive channels, and especially that of the intestines, displays, +like the external tegument in man and the brute creation, divers forms +of inflammation, analogous with the measles, the scarlatina, and the +small-pox; so that, if the typhoid fever in man, which is nothing else +than the small-pox of the intestines, is so frequently cured, it is +because the general morbid condition, the fever, often conceals +different intestinal lesions, albeit they seem to be similar in the +general symptoms, which taken collectively constitute the disease.</p> + +<p>The flesh of these diseased animals was blackish, and devoid of blood; +the animals which fed upon it, if uncooked, sickened afterwards, or +died. The wrecks of the bodies, and more particularly the skin, +sometimes retained a strength of contagion so deadly, that the mere +exportation of them was enough to cause its propagation, and to this +cause was at that time attributed the outbreak of the contagion in +England.</p> + +<p>An extraordinary case of this pernicious influence, which is related by +Hartmann, who observed this epizootia at its decline in 1756, <span class='pagenum'><a name="Page_36" id="Page_36">[Pg 36]</a></span>will give +an idea of the subtlety of this malignant virus.</p> + +<p>A farmer who had lost an ox in consequence of that virulent distemper, +buried it in one of his fields. The following night a bear smelt the ox, +raked it up with his feet, ate a portion of the flesh, and a few days +after, the beast of prey was found dead in a neighbouring wood by a +peasant in the parish of Eumaki. The skin belonging to this bear was +magnificent. The peasant flayed the animal and carried home his skin in +triumph. But his triumph was short; for that same night the poor +countryman fell ill, and died two days after the attack. The magistrates +of Wiburg, having heard of this occurrence, sent orders to have the +infected skin burned. Meanwhile, the skin had been given to the curate +of the place as a compensation for the offices of burial; but his +cupidity having persuaded him that this fine skin could not have +destroyed the peasant whom he had just buried, he did not burn it at +all, but induced another peasant to clean and dress it for him. This +simple fellow and two other clodpoles, who assisted him in the +preparation, fell ill, <span class='pagenum'><a name="Page_37" id="Page_37">[Pg 37]</a></span>and all three of them died in the course of a +few days. A new and peremptory order now came from Wiburg to burn this +skin, to burn the house in which it had been dressed, to burn even the +presbytery itself, should it be deemed necessary. The skin had already +passed through several hands. However, the curate being still reluctant +to part with it, took it home again. "Can it be possible," said he to +himself, "that this skin has really proved fatal to life? What can have +been the cause, I wonder?" At the same time he rubbed it in his hands +and smelt it. Unlucky curate! A few days afterwards he himself was taken +ill and died. (<i>Memoirs of the Academy of Stockholm.</i>)</p> + +<p>A native of Clermont Ferrand, in the department of Puy de Dôme, in +France, the birth-place of Pascal, one day finding an ox which had died +of the epizootia, stripped off the skin and carried it away. After his +return home, the black typhus, and then gangrene, broke out on one of +his arms, which had to be cut off, and the patient died of the effects +of the amputation.</p> + +<p>A butcher having slaughtered an ox smitten <span class='pagenum'><a name="Page_38" id="Page_38">[Pg 38]</a></span>with this typhus, sold the +flesh for meat to some soldiers of the Regiment Royal Bavière, then +garrisoned in one of the towns of Languedoc. All those who partook of +this meat were seized with diarrhœa, dysentery, and fever, and +several of the sick soldiers very nearly died. The butcher, whose +avarice had caused all this mischief, had richly deserved some exemplary +punishment, and some of the sufferers proposed that he should be hanged +outright, but the majority, more clement, sentenced him to be beaten +black and blue with horsewhips.</p> + +<p>The popular saying, <i>when the beast is dead the poison is dead</i>, being +generally true, the virulence of the contagion, in the above instances, +possessed venomous properties of an exceptional character, for if every +sick animal slaughtered by the butchers and sold to the consumers, or +those which had been flayed for the sake of the skin, had contained so +murderous a virus in their tissues, the number of victims to the +contagion among the human species would have been appalling. And in that +case, too, similar sacrifices would be witnessed at present, for it +cannot be doubted <span class='pagenum'><a name="Page_39" id="Page_39">[Pg 39]</a></span>that, in the actual state of the meat market in +London, the people are now in the daily habit of eating the flesh of +cattle which are diseased.</p> +<br /> + +<p class="cen">IV.</p> + +<p>Physicians of different countries have naturally bestowed much time and +care in considering and discussing the nature of this epizootia, because +they have felt that a satisfactory theory and appreciation of its +principal phenomena, might afford the medical faculty a rational basis +for some special treatment.</p> + +<p>Layard and the physicians of Geneva have considered this cattle disease +to be <i>a malignant fever with an eruptive tendency</i>.</p> + +<p>In the estimation of the faculties of Paris and Montpellier, this cattle +disease, considered in its symptoms, was nothing more than <i>a malignant +fever essentially contagious</i>, the action of which appeared to tend +exclusively towards the skin, and therefore it was rational to provoke +external eruptions and deposits which, as they matured, diverted from +the centre the greatest part of the morbific matter.</p><span class='pagenum'><a name="Page_40" id="Page_40">[Pg 40]</a></span> + +<p><i>The treatment</i>, to which, above all, we invite the reader's attention +(more particularly that of medical men), necessarily varied according to +the period of the disease. It was sometimes preservative, sometimes +curative, as the case might be.</p> + +<p><i>The Preventive Treatment.</i>—The farmers and cattle-breeders, whose +herds were still exempt from the contagion, mindful of the advice which +they received through the public press, took very particular care of +their cattle during this season of epizootia: they rubbed them over with +a brush, and washed them at least once a day; they sheltered them from +the inclemency of wind and rain; they took their milch cows, which until +then they had kept shut up in unhealthy cow-houses, into the open air of +the fields; they washed and fumigated the stables; they examined the +quality of the fodder and of the other articles of food; they added +marine salt to their drinking water, or poured salt water over their +forage; and above all, they took care that no foreign animal commingled +with their flocks and herds.</p> + +<p>Some physicians, on their side conscious of the duty which devolves upon +them in such <span class='pagenum'><a name="Page_41" id="Page_41">[Pg 41]</a></span>seasons of calamity, instead of resting satisfied with +recommending remedies, betook themselves boldly to the work, and studied +the disease experimentally in respect to its propagation and prevention.</p> + +<p>Thus, for instance, certain Dutch physicians, in 1754, wishing to know +whether the morbid matter would transmit the disease by inoculation, +made incisions in the necks of some oxen, cows and calves, inserting in +the wound a little tow saturated with the morbid secretions discharged +from the eyes and nostrils. This direct inoculation having been +practised on seventeen animals, transmitted the disease to them all in +the course of a few days.</p> + +<p>The English physicians having been made acquainted with these +experiments, applied them to a more practical purpose, no longer to +discover whether the disease could thus be transmitted (for that had +been proved), but to find out (what was far more important) whether this +fearful distemper could be prevented and kept off.</p> + +<p>Malcolm Flemming, in 1755, merely suggested the idea of inoculation as a +preventive means, without proceeding to a course of <span class='pagenum'><a name="Page_42" id="Page_42">[Pg 42]</a></span>experiments to +ratify his opinion. He intimates his notion in the following terms:—</p> + +<p>"I apprehend that inoculation will stand the better chance of bringing +on the distemper, if the subject it is performed on is as young as +safety will permit, the vessels being then most absorbent, and the +animal economy most easily put into disorder.</p> + +<p>"But even in case the inoculation of calves should be found so +successful as universally to prevail, the method I recommend will not be +altogether useless; for, by being properly modelled and adapted to +circumstances, it may, I am persuaded, prevent contagion, and likewise +act as a preparative in any epidemical affection of the inflammatory +kind, not only in horned cattle, but likewise in all other quadrupeds +that civil society may think worthy of preservation, and even in the +human species."</p> + +<p>Layard, in 1757, devotes the seventh chapter of his work, "The Means to +prevent the Infection," to the consideration of the preventive +treatment, in which he says:—</p> + +<p>"No one will think of bringing the infection into any place free from +it, merely for the sake of inoculating their cattle; but if the +<span class='pagenum'><a name="Page_43" id="Page_43">[Pg 43]</a></span>contagious distemper be in the neighbourhood of a herd, or break out so +as to endanger the stock, the grazier or farmer may, by inoculating his +cattle, with proper precautions, at least secure his stock, since he can +house them before they fall sick, prepare them, and have due care taken, +knowing the course of the distemper.</p> + +<p>"Sir William St. Quintin, the Rev. Dr. Fountayne, Dean of York, and +other gentlemen have succeeded in inoculation: in Holland it has both +failed and succeeded. These gentlemen all inoculated with matter taken +from the running of the mouth, nose, or eyes. Professor Swenke mentions +that the beast from which he took the matter was recovering from the +distemper. A circumstance to be attended to is this:—had matter been +taken after the crisis, from a tumour, boil, pimple, or scab, either on +the back near the spine, or on the legs, the pus would have proved much +more elaborated, subtle, and infecting than that which, flowing with the +mucus of the nose, must necessarily be, in some degree, sheathed by this +glutinous excretion, though I am well aware how putrid and acrid it is +rendered by the disease.</p> + +<p><span class='pagenum'><a name="Page_44" id="Page_44">[Pg 44]</a></span>"That nothing may be omitted which in any shape can contribute to the +success of inoculation, due attention should be paid to the constitution +and state of the beast, no less in this practice on the cattle than on +the human species. Undoubtedly the young, healthy, and strong bid fairer +for a good issue than the old, sickly, and feeble; each of these +different constitutions demand a particular treatment, even in the +method of preparation; and however trifling it may seem to many—the +urging a necessity of preparation—I will venture to affirm that I have +seen excellent effects arising from a rational preparation, and fatal +events from want of preparation. I have likewise been witness of +unfavourable turns, merely from an injudicious preparation.</p> + +<p>"The beasts which are sanguine require moderate bleeding; those that +have but a small share of blood must have none drawn. The strong must, +besides moderate bleeding and purging, be kept on light diet, and their +body kept open. Thus, scalded bran, mixed with their hay and chaff, will +cool them. The weakly, and such as are inclined to scour, must <span class='pagenum'><a name="Page_45" id="Page_45">[Pg 45]</a></span>be kept +on dry fodder, and have peas and beans given them to strengthen them. A +mess of malt, or a quart of warm ale, with a few spices, will be very +suitable for them.</p> + +<p>"Whatever diseases the cattle may be affected with, if time will permit, +they are first to be removed.</p> + +<p>"The cattle to be inoculated are first to be well washed, rubbed dry, +and then curried, to remove all the filth from the hair and skin. Then +they are to be placed in a spacious barn or stable, where the air is +temperate and no cold can come to them. There they are to be prepared +according to the direction already given, foddered with good sweet hay, +and watered with clear spring water; and if the distemper be not near, +they may be turned out into the air, near the barn or stable, and may +stay there a few hours in the middle of the day.</p> + +<p>"When it appears that the cattle are in perfect health, free from any +infection or disease, brisk and lively, neither costive nor scouring, +and chewing their cud, then the operation may be safely undertaken, and +henceforth they must be confined to the barn.</p> + +<p><span class='pagenum'><a name="Page_46" id="Page_46">[Pg 46]</a></span>"Since there is observed to follow the greatest flow of the contagious +and putrid particles separated from the blood, wherever the infectious +matter makes an impression at first, particular care must be taken not +to inoculate near such vital parts as the heart and lungs, nor near the +womb, if a cow with calf be inoculated; for, though rowels are properly +applied in the dewlaps to draw off the pestilential humour from the +breast, and in other cases beasts are frequently rowelled in the +flanks,—yet, in this operation, as matter is inserted by these channels +into the neighbouring vessels, those vital parts, or the womb, might +become the chief seat of the disease, and the event prove fatal.</p> + +<p>"To prevent such accidents, human beings have been inoculated on the +arms and legs, and now-a-days the arms are found sufficient. I would +recommend that the cattle should be inoculated about the middle of the +shoulders or buttocks, on both sides, to have the benefit of two drains. +The skin is to be cut lengthways two inches, deep enough for the blood +to start, but not to bleed much. In this incision is to be put a dossil +or pledget <span class='pagenum'><a name="Page_47" id="Page_47">[Pg 47]</a></span>of tow, dipped in the matter of a boil full ripe, opened in +the back of a young calf recovering from the distemper. It may not be +amiss to stitch up the wound, to keep the tow in, and let it remain +forty-eight hours. Then the stitches are to be cut, the tow taken out, +and the wound dressed with yellow basilicum ointment, or one made with +turpentine and yolk of egg, spread on pledgets of tow. These dressings +are to be continued during the whole illness, and till after the +recovery of the beast, to promote the discharge; and then the wound may +be healed with the cerate of lapis calaminaris, or any other.</p> + +<p>"On the third day after inoculation, the discolouring of the wound, +whose lips appear grey and swollen, will be a sign that the inoculation +has succeeded; but the beasts, as Professor Swenke informs us, did not +fall ill till the sixth day, which answers exactly to the observations +daily made in the inoculating of children. Yet the Professor adds that +on the third day a costiveness came on, which was removed by giving each +calf three ounces of Epsom salts.</p> + +<p>"No sooner do the symptoms of heaviness <span class='pagenum'><a name="Page_48" id="Page_48">[Pg 48]</a></span>and stupidity appear than the +beasts must have a light covering thrown over them, and at night +fastened loosely. They must be rubbed morning and evening, and curried, +till the boils begin to rise; warm hay-water and vinegar-whey must be +given plentifully. Should the beasts require more nourishment, dry meat, +such as cut hay, with a little bran, may be offered. I should be very +cautious in giving milk-pottage, even after the boils and pimples had +all come out, for fear of bringing on a scouring. However, this caution +is proper, that whenever milk-pottage be given, the vinegar-whey is to +be omitted for obvious reasons. In cases of accident, the same attention +is to be observed in the disease by inoculation as in the natural way, +and the medicines recommended are the same I would use; but by +inoculation there seldom is a call for any, so favourably does the +distemper proceed through its several stages.</p> + +<p>"The crisis being over, it will be proper to purge the cattle, to air +them by degrees, and to have the same regard in the management of them +as is laid down in the chapter on the method of cure."</p> + +<p><span class='pagenum'><a name="Page_49" id="Page_49">[Pg 49]</a></span>Such are the recommendations which Layard has prescribed for those who +have to practise inoculation as a preventive treatment; it would be +difficult to offer an example of greater prudence or precision.</p> + +<p>A certain number of oxen were, by means of this inoculation, protected +against the attack of the cattle disease; and this mode of treatment +was, as we shall afterwards explain, adopted in Russia. Unfortunately, +this rational and preventive treatment was discovered only at the end of +the epizootia, when already upwards of six millions of horned cattle had +fallen a sacrifice to the contagious fever.</p> + +<p><i>Curative Means.</i>—When the first course of the disease had left no +doubt of the attack, the sick animal was subjected to an appropriate +diet, and restricted to liquids either as medicinal decoctions, or as +alimentary beverages. The decoctions consisted of whey mixed with a +little vinegar, and nitred hay. The broths, or alimentary beverages, +consisted of a decoction of bread, and of water mixed with bran and +meal, whether of barley, oats, or wheat.</p> + +<p><span class='pagenum'><a name="Page_50" id="Page_50">[Pg 50]</a></span>At this stage of the curative process, the majority of physicians +recommended one or two bleedings, in order to abate the violence of the +fever, and of the congestions near the nervous centres and the lungs; +and as constipation prevailed at the time, they strove with the same +object to empty the digestive passages, the intestines, and the +stomachs, notwithstanding the difficulty that exists to produce this +result in ruminating animals.</p> + +<p>The purgatives employed consisted of a decoction of senna, mixed with +prune juice, with a little rhubarb or fresh linseed oil, infused in +their drink, or applied as a clyster in warm water slightly salted. +Those who practised polypharmacy administered at night a mixture of +nitre, camphor, red-lead, and rhubarb, in half a pailful of warm water; +and greatly did they boast of the active influence of this beverage.</p> + +<p>Some practitioners even endeavoured, in the first stage of the malady, +to accelerate its action on the skin by giving for that purpose warm +drinks, and by covering the cattle with woollen cloths, to promote +perspiration; but it was generally admitted that the sick animals +<span class='pagenum'><a name="Page_51" id="Page_51">[Pg 51]</a></span>preferred cold drinks, and that they were particularly fond of +acidulated whey.</p> + +<p>In the second period of the distemper, the same drinks were continued, +adding thereto some theriac or Jesuit's bark, in order to lessen the +frequency of the diarrhœtic evacuations. They also provoked the +depurating secretions from the mouth, nose, and eyes, by repeated +washings; and as those animals, in which the running was most easy and +copious, seemed to be less seriously affected with the disease, they +strove to increase that which flowed from the glands of the mouth by +fixing a gag in the jaws, and keeping it there for several hours. This +measure seemed so efficacious that a decree from the Parlement de Rouen, +issued on the 13th of March, 1745, ordered the application of a gag, or +bit, for three hours every day, to the cattle under treatment.</p> + +<p>In the third period, they sought to overcome the wasting of strength in +the system by means of tonic and nutritious drinks, decoctions of +centaury, Jesuit's bark, juniper berries, &c. They likewise administered +emollient clysters if the evacuations were bloody.</p> + +<p><span class='pagenum'><a name="Page_52" id="Page_52">[Pg 52]</a></span>Moreover, they placed two or three setons, principally in the dewlap, in +order to obey the signs and indications of nature—<i>quo natura vergit, eo +ducendum</i>; as a salutary and critical eruption of the skin was at that +period forcing its way. These setons were kept open with a mixture of +turpentine and yolks of egg, for the purpose of encouraging the +secretion. The purulent or emphysematous tumours were cut.</p> + +<p>But whatever means might be employed, almost all the cattle perished, +and the few and rare recoveries only afforded the pessimists the +satisfaction of claiming the merit of them for themselves. It was +remarked, besides, that the fattest beasts were the least able to resist +the effects of the distemper.</p> + +<p>It is hardly necessary to say, that during the whole course of the +treatment, great care was taken to keep both the stables and the cattle +in a perfect state of cleanliness.</p> + +<p>The convalescence of those animals which were cured was invariably long, +and required great attention as to their food and hygienic treatment. +Solid substances, roots, and forage were withheld until rumination +revived; and it was only after several days of encouraging <span class='pagenum'><a name="Page_53" id="Page_53">[Pg 53]</a></span>trials that +the recovered animal was suffered at last to feed all day in the field, +according to his pleasure.</p> + +<p>Such, then, was that formidable epizootia which, in the middle of the +eighteenth century, swept away upwards of six millions of horned cattle, +and which occasioned a loss to Europe exceeding fifty millions +sterling—perhaps we might say a hundred millions—for other domestic +animals, sheep, horses, &c. (as generally happens in cases of +epizootia), had likewise suffered, in different degrees, from the +various complaints arising from inclement seasons.</p> + +<p>It was certainly necessary to our purpose that we should have taken this +retrospective view of the cattle disease, and it will afford us a +valuable guide for the future. We may now content ourselves with +bringing together the different annals in the chain of time which +elapsed between Layard's treatise, which was published in 1757, and the +present day. This chain of time amounts to 108 years.</p> +<br /> + +<p class="cen"><span class='pagenum'><a name="Page_54" id="Page_54">[Pg 54]</a></span>V.</p> + +<p>The typhus of Horned Cattle, which had shown itself in a manner +permanent, sometimes raging at one part of the globe, sometimes at +another, could not, under the unaltered conditions by which it had been +generated, suspend its ravages; and though, thanks to her isolated +position, England may be less exposed to it than other countries, it is, +however, necessary to take note of what may serve for our instruction in +the several epizootics which will pass under our view.</p> + +<p>Medical writers relate that contagious typhus broke out several times in +Holland during the years 1768, 1769, and 1770; it also appeared in +French Flanders in 1771, in Hainault in 1773. In France one particular +spot was, at this period, completely rendered intact by drawing a +sanitary fence about its limits, and bestowing on the cattle particular +hygienic attention as a safeguard. The stables of these animals were +washed, cleansed, and fumigated; spring water was given them to drink, +their food was chosen with care, and a certain quantity of salt was +mixed with it.</p> + +<p><span class='pagenum'><a name="Page_55" id="Page_55">[Pg 55]</a></span>In 1774, Holland, a cold and damp country, was once more invaded by the +scourge; and the Government offered in vain a reward of 80,000 florins +to any one who should discover the preventive or specific remedy for the +disease.</p> + +<p>The typhus which, at that epoch, had likewise broken out again in the +south of France, threatened to become an abiding peril to the wealth of +nations. Two French authors, Vicq d'Azyr and Paulet, betook themselves +earnestly to the task of collecting every document which up to that time +had been published on the successive visitations of the malady, and of +offering the means of preventing it. Their intention was unquestionably +laudable, but the time for obtaining such a result had not yet arrived; +besides which, these two writers, whatever may have been their desert, +were not equal to an achievement of this character. They belonged, +indeed, to that order of men who look upon the cultivation of science +solely as a step to personal distinction.</p> + +<p>Vicq d'Azyr himself was but twenty-five years old when he issued, in +1775, his work, <span class='pagenum'><a name="Page_56" id="Page_56">[Pg 56]</a></span>entitled, "Exposé des Moyens curatifs et preservatifs +qui peuvent être employés contre les Maladies des Bêtes à Cornes." We +should deceive ourselves if we expected to find in this exposition +anything but an interesting compilation of the works already published.</p> + +<p>Paulet's treatise appeared likewise in 1775, under the title, +"Recherches historiques et physiques sur les Maladies epizootiques, avec +les Moyens d'y rémédier dans tous les Cas, publiées <i>par ordre du Roi</i>." +Paris. Two volumes.</p> + +<p>After reading and reflecting on this title, as servile as it is +arrogant, I might have dispensed with all examination of the work. A +scientific man, whilst in the pursuit of truth, takes orders from +nobody, not even from kings. Paulet, therefore, writing <i>by order</i>, +could only produce a work of mediocrity, and such is incontestably the +degree of value of his two volumes, forming, as they do, a fastidious +dissertation of epizootics in general, and of those relating to cattle +in particular.</p> + +<p>The works of Paulet and Vicq d'Azyr, written at the same time, not being +the labour of men practising the medical art, are on a level as to the +notions which they have handed <span class='pagenum'><a name="Page_57" id="Page_57">[Pg 57]</a></span>down to us; but that of Vicq d'Azyr +being the better of the two, we shall extract therefrom what may chiefly +interest us.</p> + +<p>Vicq d'Azyr relates the history of the epizootics, and expatiates on the +original cause of the typhus in horned cattle, and on its nature. The +passages in which he treats of its mode of propagation and its +treatment, are the most deserving of our notice.</p> + +<p>He says, that he tried to no purpose to communicate the disease a second +time to animals which had been fortunate enough to get cured.</p> + +<p>That cows covered with the fresh skins stripped from dead cattle, +victims to the distemper, did not contract it.</p> + +<p>That infected clothes which had been worn by men who had served in +hospitals where cattle were under treatment, having been laid on the +backs of several beasts in sound health, were found to transmit the +distemper in three cases out of six.</p> + +<p>That the gases expelled from the intestines, received into a bladder +ball, and let out under the noses of healthy cattle, have communicated +the disease to them, after ten or fifteen days <span class='pagenum'><a name="Page_58" id="Page_58">[Pg 58]</a></span>of latent incubation; +and that the same gases being mixed with their drink, have also +propagated the contagion.</p> + +<p>That frictions, with the hands impregnated with virus, having been made +over the skin, did not produce any ill effects.</p> + +<p>That some oxen which had been designedly placed for a few hours among +sick animals, have afterwards been seized with the distemper.</p> + +<p>That a calf which had been placed in a stall containing some oxen +grievously affected, but which calf had a basket beneath its nose filled +with aromatic herbs, withstood the contagion.</p> + +<p>That cowsheds which had been partially cleansed and fumigated, +transmitted the disease to other cattle, even several months after they +had been vacated.</p> + +<p>Finally, he mentions the experiments of inoculation made by Lay and in +England, but not understanding their aim and capacity, he adds, that +inoculation does not seem to him of any use, since the inoculated +animals all died. Yet he quotes the encouraging results obtained by +Camper in Holland, who, out of <span class='pagenum'><a name="Page_59" id="Page_59">[Pg 59]</a></span>112 inoculated cattle, saved 41; and +those of Koopman, who, out of 94, cured 45 by this very inoculation.</p> + +<p>He reminds us that the cattle typhus is an abiding disease in Hungary +and Russia, where the beasts having bad water to drink, can only be +protected by a constant use of marine salt (<i>sel gemme</i>); but being +deprived of this salt, when they go great distances to be sold, and +being exposed to extreme fatigue and privations, the typhus then spreads +among them. He likewise tells us that Hungary and Dalmatia, which used +to supply the markets of Italy with butcher's meat, were obliged to give +up sending any cattle there, the Italians having firmly refused to +purchase the same at any price whatever.</p> + +<p>As regards treatment, the advice which Vicq d'Azyr gives to +agriculturists, is mostly borrowed from the authors who have written on +the great epizootics of 1711, and 1745 to 1755. Thus, he advises them to +give as drinks in the first stage, water whitened with meal and nitred; +to purge the animals with linseed oil; even to make scarifications on +the skin, and to keep up the suppuration <span class='pagenum'><a name="Page_60" id="Page_60">[Pg 60]</a></span>with turpentine; to make the +animals inhale six times a day vapours seasoned with vinegar; to wrap +them over with woollen cloths; to bleed them once or twice; to +administer to them, when diarrhœa shows itself, a beverage containing +wormwood, quinine, and diascordium; to cut open the tumours containing +pus or air, etc.</p> + +<p>It is, as is seen, the same treatment as that quoted above; he +guarantees its success, and supports his views by the authority of Van +Swieten and Huxan.</p> + +<p>Van Swieten, however, had somewhat modified the treatment, by the +predominance which he allowed to acids; and this course seemed to him to +be only reasonable with respect to animals whose sick humours contain an +excess of alkali.</p> + +<p>Vicq d'Azyr fixed his attention on the means of prevention, the most +effectual of which, in his opinion, was to slaughter every animal which +had either sickened, or had been exposed to the influence of the +contagion; and as he insisted that the authorities had no measures to +keep in this matter of public interest, he made it a principle that the +<span class='pagenum'><a name="Page_61" id="Page_61">[Pg 61]</a></span>government was bound to compensate the cattle proprietors whose animals +had to be killed—the more so, said he, that the crafty husbandmen would +never come forward and freely declare the invalidity of their cattle, +unless some indemnity were held out to them, which they would look upon +as a sort of equivalent for the benefits they had expected by cutting +them up and selling them as the food of man.</p> + +<p>The doctors of the period, scenting in Vicq d'Azyr a dangerous +competitor, considered the advice of exterminating the diseased cattle +as an <i>ingenious means of curing</i> them, and as the author's age and +experience gave warrant for this satirical tone of discussion, the +public joined them in laughing at him.</p> + +<p>The epizootic typhus, if not so destructive, was at least as frequent in +the early part of the nineteenth century, as it had been during the +eighteenth. The armies during the wars of united Europe against the +French Republic and Empire, found it constantly in their train. Nor +could it be otherwise, the two leading causes of its prevalence being at +hand. For on one hand there was the transit of large <span class='pagenum'><a name="Page_62" id="Page_62">[Pg 62]</a></span>herds from the +steppes of Hungary, and on the other the wretched hygienic conditions +amidst which the cattle had to live in the campaigning armies.</p> + +<p>Many books have been published of late years on the diseases of cattle, +in France and Germany; and several distinguished English veterinary +surgeons, especially Professor Simonds, have also devoted their +attention to the same subject. In the second part of this work, we shall +have occasion to refer to their labours.</p> + +<p>In France, Renault, Delafond, d'Arboval, Gellé, whose works enjoy a +deserved reputation, have discussed the subject of the origin of this +disease.</p> + +<p>Renault asserts that the disease has but one single focus, the steppes +of Russia and Hungary. The epizootics of Asia, Africa, and South America +are caused, he considers, by the importation of animals to those +countries. It is thus that he explains the epizootia which, under the +name of Delombodera, devastated the American Republics in 1832, and that +which, in 1841, appeared in Egypt. Renault thinks that neither the long +transit, nor the filthy state <span class='pagenum'><a name="Page_63" id="Page_63">[Pg 63]</a></span>of the markets, nor the most wretched +feeding, are sufficient to account for contagious typhus among cattle; +that in addition to these causes, it still requires, in order to produce +and generate it among animals, a predisposition, and a special aptitude, +such as, hitherto at least, do not appear to have been witnessed except +in the progeny of the steppes.</p> + +<p>The other professors of his fraternity have submitted arguments to him, +which to us seem very rational; and we will endeavour to do justice to +them when we discuss the origin of the typhus which at this moment is +afflicting England.</p> +<br /> + +<p class="cen">VI.</p> + +<p>These historical dissertations and speculations on the subject of the +bovine epizootia certainly deserve to draw the attention of all who feel +an interest in the malady; but how insignificant they are compared with +the concluding facts which I have still to mention, before I at length +address myself to the consideration of the epizootia which is now +consuming our herds!</p> + +<p>The indisputable fact that so terrible a <span class='pagenum'><a name="Page_64" id="Page_64">[Pg 64]</a></span>distemper as this typhus had +fixed itself permanently in Russia, and that it was causing incalculable +losses to the lordly proprietors of the steppes, as well as to the +government, roused them at last from their indifference. Then, indeed, +they urged the veterinary doctors to adopt some energetic means to +arrest the long duration of the scourge, and we must admit to their +honour, that various experiments which were tried for the purpose of +preventing the evil, have been crowned with complete success. Any one +may ascertain the fact by referring to the <i>Journal Magazin</i> of Berlin, +in which the learned Professor Jessen of Dorpat has explained the +results of these important experiments.</p> + +<p>The Russian veterinarians having observed that the oxen which had been +cured of the typhus could mingle with impunity with the infected herds, +conceived the idea of communicating the complaint to sound cattle by +means of inoculation, and thereby to shield them from the contagion.</p> + +<p>The first experiments in the inoculation of <i>Tchouma</i> or cattle typhus, +were made in the year 1853, by order of the government, in <span class='pagenum'><a name="Page_65" id="Page_65">[Pg 65]</a></span>the +neighbourhood of Odessa, at the Heridin farm, by Professor Jessen.</p> + +<p>The first inoculative attempts were very fatal; they caused the death of +all the inoculated animals. But it was soon perceived that these +grievous results, far from prejudicing the theory, really confirmed it; +and that the virus, attenuated in its toxical properties, would prove as +effectual as was expected. And truly, in 1854 and 1855, at the Dorpat +establishment, the inoculations made with a better selected virus +afforded results less disastrous. At Kozau they were still more +satisfactory. In fine, passing from experiment to experiment, they +arrived at the conclusion that it was necessary to inoculate several +heads of cattle, the one after the other, without having recourse to any +other virus than the first inoculated, so that they might thereby obtain +virus of the 2nd, 3rd, 4th, 5th, and up to the 10th generation. The +virus thus attenuated in its morbid effects answered at length every +experiment, and oxen thus inoculated could mingle with impunity with +diseased cattle.</p> + +<p>At the veterinary establishment of Chalkoff <span class='pagenum'><a name="Page_66" id="Page_66">[Pg 66]</a></span>they inoculated, during +eight meetings, 1059 animals with virus of the 3rd generation, and the +results were as satisfactory as could be wished for, only 60 animals +having sunk under the effects of this preventive operation.</p> + +<p>The inoculations made in 1857 and 1858 on an estate belonging to the +Duchess Helena, at Karlowska, in the government of Pultawa, and +conducted by the veterinarian Raussels, likewise afforded the most +satisfactory results.</p> + +<p>Professor Jessen thinks it certain, that beasts born of cows which have +been afflicted with contagious typhus do not contract the disease. He +maintains that Europe may be preserved from this frightful scourge, by +taking care that no cattle be exported from the steppes of Russia save +those which have had the distemper either naturally or by inoculation, +and he is striving to propagate this opinion, and to render it +practical, by having all the cattle inoculated, without exception.</p> + +<p>It is deeply to be regretted that counsels so prudent have not been +heeded in the 47 governments which, out of the 53 possessed by Russia, +have generated the contagious typhus; for then it would not so +frequently <span class='pagenum'><a name="Page_67" id="Page_67">[Pg 67]</a></span>have effected its passage into the neighbouring states, and +England most probably, would not now have to take up arms against its +fatal extension.</p> +<br /> + +<p class="cen">VII.</p> + +<p>We here conclude that part of our labour which includes the history of +this disease, and what we have been able to glean from those medical +writers, and others, who have given us the results of their experience. +It may have appeared somewhat protracted, but it has at least laid open +to the student the antecedent investigations of our predecessors, under +calamities of the same kind, but considerably more fatal than what has +yet been witnessed in Western Europe during our time. We have +disinterred and brought to light the forgotten works of conscientious +and competent men. Like Brunelleschi, the architect, we have sought, not +to invent a theory, but to recover a practice; and thus we have received +the observations and precious facts, and finally the preventive +treatment, of other men and other times, which had coped successfully +against the cattle disease when its ravages were infinitely greater.</p> + +<p><span class='pagenum'><a name="Page_68" id="Page_68">[Pg 68]</a></span>To resume, then: these inquiries (which we undertook without +anticipating so rich a harvest) have proved, and made evident—</p> + +<p>That the contagious typhus afflicting horned cattle, has spread its +destructive principle over our globe ever since there have been animals +living on its surface.</p> + +<p>That from century to century, not to say from year to year, it has +carried its terrors amidst nations and peoples.</p> + +<p>That the remedial measures which had been taken and applied prior to the +middle of the eighteenth century, were utterly powerless either to cure +this disease or to prevent it.</p> + +<p>That at that period appeared two English physicians, men of remarkable +aptitude and penetration, one of whom, Malcolm Flemming, laid down in +theory the bases of a preventive treatment; whilst the other, Peter +Layard, applied this theory to practice, by inoculating sound and +healthy animals with the morbid virus of the typhus, in order to protect +them from the fatal effects of the contagion.</p> + +<p>That this all-important progress in medical experience, has been +absolutely forgotten; so much so, indeed, that the experiments of +<span class='pagenum'><a name="Page_69" id="Page_69">[Pg 69]</a></span>inoculation, tried in Russia only ten or twelve years ago with perfect +success, do not seem to be connected by any link with those made in +England a century before, and that the invasion of the so-called +<span class="smcap">Cattle Plague</span> in 1865 seemed to some men to have introduced a +new scourge, which men were not armed and prepared to meet—which they +were powerless to cure, or to stay in its progress.</p> + +<p>These inquiries, then, have proved, we think, that we are not so +helpless as we had imagined to resist the evil. But we cannot help +feeling, that we have laid bare in this exposition some most distressing +inferences concerning the human mind. For, in truth, can anything be +more deplorable, than thus to see the civilized nations of Europe +endure, from century to century, these reiterated outbreaks of cattle +typhus, and to see likewise that no man of sufficient energy and +independence has yet arisen to tell the truth fearlessly to the +governments and peoples, however painful that truth may be, and to +expose the futility of the measures hitherto employed to arrest the +scourge?</p> + +<p>And, on the other hand, is it not most <span class='pagenum'><a name="Page_70" id="Page_70">[Pg 70]</a></span>afflicting to see discoveries of +indisputable value buried out of view, submerged in public libraries, +utterly unknown and forgotten, like their authors, to such a degree, +that the distemper which they have made known in its entirety, and which +is as old as the world itself, seems to us almost new in 1865?</p> + +<p>God send, that these cruel trials and severe lessons which the past has +bequeathed to us may teach us something for our benefit! May the +irresistible might which is derived from the auspicious union of capital +and intelligence supersede the vain and flimsy efforts of isolated +energy! May the government, which lavishes hundreds of millions upon the +destructive engines of war, devote some portion of its ample means to +the study of hereditary infections and contagious diseases! For these +fatal epidemics decimate men as well as cattle, and we may at least ward +off from our children the desolating disease which at present afflicts +ourselves.</p> + +<p>We possess already every requisite means to protect ourselves from the +formidable visitation of these diseases: we have science; we have the +men who cultivate and teach it; we <span class='pagenum'><a name="Page_71" id="Page_71">[Pg 71]</a></span>have the experience of the past +added to our own. To-day, we are called upon to resist the baleful +effects of cattle typhus; but another epizootia may come to-morrow, and +strike our horses and our sheep—those domestic animals which constitute +our most precious possession. The cholera hovers about us. If we do +nothing, if we talk and debate instead of acting, these scourges will +come upon us on a sudden, and find us quite as helpless as ever to +resist their sway.</p> + +<p>These palpable truths deserve to be further developed, and will be +treated more copiously at the end of this book. They will constitute the +complement of our work, necessarily written in haste, since the danger +we had to expose was itself so urgent and alarming.</p> + +<h4>FOOTNOTE:</h4> + +<div class="footnote"><p class="noin"><a name="Footnote_A_1" id="Footnote_A_1"></a><a href="#FNanchor_A_1"><span class="label">[A]</span></a> To assist the researches of other inquirers on this vital +subject, now so generally interesting, we may add, that the cattle +treatises already referred to—of Malcolm Flemming and Peter Layard—are +to be found in the Library of the British Museum, bound together in a +single volume, which is certainly worth ten times its weight in gold. It +contains, indeed, eight different opuscula, all relating to cattle +complaints, which scientific students may consult with real +gratification. I will here transcribe the titles of the most important +of these treatises, the pregnant expositions of the two English +physicians above-named. +</p><p class="noin"> +That of Malcolm Flemming: +</p><p class="noin"> +"A Proposal, in order to Diminish the Progress of the Distemper among +the Horned Cattle, supported by Facts. London, 1755." +</p><p class="noin"> +That of Peter Layard: +</p><p class="noin"> +"An Essay on the Nature, Cause, and Cure of the Contagious Distemper +among the Horned Cattle in these Kingdoms. London, 1757." +</p><p class="noin"> +A great many accounts, treatises, and expositions on the same subject +appeared at the same time in France, Holland, Denmark, and Switzerland. +One, which appeared in the last of these countries, is entitled: +</p><p class="noin"> +"Reflexions sur la Maladie du Gros Bétail, par la Société des Médecius +de Genève. 1756."</p></div> +<br /> +<br /> +<br /><span class='pagenum'><a name="Page_72" id="Page_72">[Pg 72]</a></span> +<br /> + +<hr /> +<br /> +<h2>SECOND PART.</h2> + +<p>This Part is divided, as already stated, into four chapters.</p> +<br /> +<br /> +<br /> +<br /> + +<hr /> +<br /> +<h2>CHAPTER I.</h2> + +<p class="cen"><i>On Typhous Diseases in general, and the Typhus which affects the Ox in +particular.</i></p> +<br /> + +<p>By following the example of those authors who have described the +contagious typhus of the ox, we might proceed at once to explain its +symptoms, and go directly to our purpose; but, by taking this hasty +course, we should expose ourselves to be imperfectly understood by the +majority of our readers, and to leave certain doubts in the minds of +physicians as to the nature of the disease and the propriety of its +treatment.</p> + +<p>All animals, including man himself, are born with a predisposition and +liability to <span class='pagenum'><a name="Page_73" id="Page_73">[Pg 73]</a></span>contract a certain number of contagious febrile diseases; +they bear in a manner a certain number of physiological elements, which +might be called latent germs, and which, under given conditions, become +the leaven of these diseases. This must, indeed, be the case, since +after these disorders have been once developed those who have been cured +of them are not apt to contract them again, the morbid developments +having destroyed that natural aptitude which had previously existed to +undergo the morbid action of the contagious virus. These diseases are +not numerous; they constitute a very distinct class, and the same laws, +which regulate the phenomena in one of them are applicable to all the +rest.</p> + +<p>These diseases exhibit the following characteristics: 1st, a period of +incubation, during which the whole economy, more particularly the blood +and humours, experience very important changes and modifications; 2nd, a +febrile state, which varies in its continuous or intermittent types, and +in its intensity, according to the species of the animals, and which +proceeds from the alteration of the blood; 3rd, a revulsion at once +toxical and <span class='pagenum'><a name="Page_74" id="Page_74">[Pg 74]</a></span>congestive towards the nervous centre, inducing <i>stupor</i>; +4th, a flux of mucus from the mouth and chest; 5th, a more intense, +congestive, and inflammatory flux or discharge from the external or +internal teguments—the skin or the mucous membrane of the digestive +channels; 6th, a period of adynamia and dejection, with a tendency, in +some cases, to a critical or salutary rejection of the morbid matter by +the development of tumours or abscesses in the skin; 7th, they are at +once infectious and contagious, epizootic or epidemic; that is to say, +they are transmitted in different degrees by contact, by inoculation, +and at a distance by the means of vitiated air; 8th, finally—and this +is their leading characteristic—<i>they are not subject to recurrence</i>, +each individual that has once been affected, losing in general all +aptitude to contract the disease a second time.</p> + +<p>This last characteristic, when well understood, ought in reason to +induce us to have recourse to the preventive treatment, and such has +been the case with respect to the most virulent amongst them—small-pox +and the typhus of the ox.</p> + +<p><span class='pagenum'><a name="Page_75" id="Page_75">[Pg 75]</a></span>Prompted by these principles, which are as logical and fixed as any +mathematical deduction, I suggested in 1855 that inoculation should be +applied in typhoid fever, which is nothing else but the equivalent of +intestinal small-pox, in order to prevent the disease in men. But if the +simplest truth sometimes requires a contest of ages before it is heard +and understood, I could not hope to fix attention on a fact which might +be taken as problematical. I felt that I was outrunning time, and that I +should neither be heard nor understood; and so it has proved.</p> + +<p>Be that as it may, these typhous diseases have, as is seen, their laws +and foreseen development. They attack animals generally, but chiefly +herbivorous animals, endowed, as we have shown in the first part, with a +vital resistance which is, relatively speaking, very inconsiderable.</p> + +<p>These febrile typhous diseases (whether their development is caused by a +spontaneous morbid action in the patient or by an evident contagion), +have a period of incubation during which the vital strength undergoes +latent morbid modifications, though not sufficient to <span class='pagenum'><a name="Page_76" id="Page_76">[Pg 76]</a></span>indicate, save in +times of epizootics and epidemics, the particular form which is about to +reveal its symptoms in the course of a few days. This period of +incubation being over, the mouth and chest become affected, and fever +declares itself; and then the <i>materies morbi</i>, which is to become the +special and dominant characteristic of the distemper, is directed either +to the skin, or to the digestive mucous membrane. In the first case, we +see evidence of exanthematic diseases, which present only the lightest +forms of detersive disorders, such as measles, scarlatina, or that more +serious one, from its pustulous form, the small-pox. In the second case, +the elimination takes place from the intestinal canal, and then we see +produced in animals, as well as in men, the typhous diseases: that is to +say, the typhoid fever—a pustulous and ulcerous malady of the +intestines—or the common typhus of the hospitals, prisons, and +campaigning armies; and again, in animals, there is also the typhus of +the steppes, of the marshes, &c.</p> + +<p>The Eastern pestilence, the plague of Rome in the age of Antoninus and +the plague of Athens, which might have given to <span class='pagenum'><a name="Page_77" id="Page_77">[Pg 77]</a></span>Hippocrates the right +of treating with Artaxerxes as one potentate treats with another, ought +perhaps to be classed among those typhuses not subject to recurrence.</p> + +<p>As for the <i>cholera</i>, it seems to be a contagious and epidemic disorder, +of a distinct and particular kind. We are ignorant of its essential +cause, its nature, and its mode of treatment; and although it has +prevailed in every age, and even frequently of late years, it will +always, by reason of the strange formation of our medical institutions, +find us as weak and defenceless to resist its attack as we have ever +been.</p> + +<p>If we have been properly understood, typhous diseases are, above all, +general febrile affections. At one time the <i>materies morbi</i>, or +discharge, affects the skin; at another, the digestive mucous membrane. +When it acts upon the skin, as clinical observation shows, there is +sometimes a sort of hesitation in the eruptive process; people wonder +what disease is coming forth; the eruption wavers in the form it will +assume, till at length its real character is determined. The same +uncertainty prevails when the intestines are affected. <span class='pagenum'><a name="Page_78" id="Page_78">[Pg 78]</a></span>Sometimes the +exanthema is merely the equivalent of simple measles or scarlatina of +the intestinal mucous membrane, and many typhoid fevers of short +continuance are nothing else in their nature. The same occurs in common +typhuses. Sometimes the local affection proceeds as far as pustulous +eruption, sometimes only to exanthematic rubefaction; hence the various +alterations which we have witnessed in the intestines of cattle killed +in our presence at the slaughter-houses of the Metropolitan Market, and +which we ourselves dissected. The experienced Professor Bouley, from the +Ecole Vétérinaire of Alfort, near Paris, whose visit must have been +beneficial to England, clearly recognised in an ox which was slaughtered +and dissected at the Metropolitan Market, the genuine pustule of typhoid +fever. But in most cases, as we shall show, it is the other forms which +prevail.</p> + +<p>We make these observations in order to anticipate the objections of +those reasoners who, being more influenced and guided by the local facts +and by the symptoms, than by the general phenomena of comparative +pathology, <span class='pagenum'><a name="Page_79" id="Page_79">[Pg 79]</a></span>might argue that such or such fact is opposed to our +doctrine.</p> + +<p>In a word, then, typhous diseases have their types; but the living being +is subjected to so many different influences, hereditary, idiosyncratic, +climataic, hygienic, &c., that by the side of one subject going through +the course of morbid phenomena with fatal regularity, another may be +seen in which such or such functional derangement is readily +distinguished. Thus in some animals, predisposed thereto by prior +disorders, the morbid action originally propelled towards the channels +of respiration will continue to be most salient; and after dissection +the lungs will be congested and emphysematous, and the intestines +relatively but scarcely altered. The animal, indeed, though bordering on +typhus, will sink under the effect of functional derangement in the +breathing passages. In others, by the influence of some particular +predisposing cause, disorders of the nervous centres will be signalized; +a cerebral and spinal pains will be intolerable, delirium will quickly +ensue, and the asphyxiated patient, if a man, will succumb in the course +of a few <span class='pagenum'><a name="Page_80" id="Page_80">[Pg 80]</a></span>days; or if an ox, he will be wild and ungovernable, and then +fall as if thunderstruck, fastened to his stall. Finally, in other +cases, these first two phases of the distemper will not prove fatal, the +intestinal injuries will pursue their course, and the affected animals +will not die until the third period.</p> + +<p>As we have seen, the morbid phenomena may be different, although the +affection continues the same; the typhoid fever or the typhus being +nevertheless the essential disease which prevails.</p> + +<p>These generalities, to some readers, may appear irrelevant, but let them +not be mistaken; they have a claim to our notice, and are really +important. They show, indeed, that independent of the preventive +treatment, which is an absolute rule in the case of virulent, +contagious, and non-recurring diseases, the treatment of the disease +itself, when it has declared itself, and when it pursues its course, +cannot be the same for every patient; and that, moreover, this treatment +must vary in the different phases of the disease, as physicians and +veterinarians are well aware.</p> + +<p>These generalities, likewise, explain the <span class='pagenum'><a name="Page_81" id="Page_81">[Pg 81]</a></span>various diseases—viz., those +in which the animals blend together the typhous and exanthematic +diseases. The measles and the scarlet fever, affecting the external or +internal membranes, are like the first steps of these maladies; they are +generally slight, and we have but to watch over the progress of the +symptoms, and to assist nature, which, with few exceptions, brings all +things to a favourable issue.</p> + +<p>These disorders, which are relatively slight and do not provoke in the +economy any of those changes which in some sort transform the +constitution, are not absolutely proof against relapse. They lead us +rationally and by degrees to the more infectious and contagious +diseases, to the common typhus; therefore it is unnecessary to apply the +preventive treatment to them, that being exclusively reserved for the +latter.</p> + +<p>Let it then be well understood, that the typhus of the ox, the study of +which we are about to enter upon, may vary in its symptoms and +post-mortem appearances, without losing thereby the characteristic mark +which renders it a thoroughly distinct, and, in the present day, a +thoroughly well known distemper.</p> + +<p><span class='pagenum'><a name="Page_82" id="Page_82">[Pg 82]</a></span>Now that the reader possesses these general notions of the Contagious +Typhus, we shall be able to speak to him in a language which he will +understand, and give a definition which he will be able to judge and +appreciate.</p> + +<p>The typhus of the ox, then, is a <i>virulent, contagious, febrile, and +non-recurring disease, with stupor and derangement of the nervous, +respiratory, and digestive functions; leaving various changes in the +respective organs of these functions, and chiefly in the intestines</i>.</p> + +<p>This new definition seems to us to be more faithful and just than those +hitherto given; and this, if needed, we could demonstrate.</p> + +<p>I do not disguise from myself that some of the opinions expressed in +these generalities may, at first sight, appear strange and liable to +objection. Thus, it may be argued that inoculation as a preventive +treatment of typhous maladies is far from being a general law, +applicable to every case; since in Russia, for instance, where this +inoculation is practised every day, it completely fails in certain +foreign herds, and they die of the consequences of the operation; and +that this, therefore, might happen in England.</p> + +<p><span class='pagenum'><a name="Page_83" id="Page_83">[Pg 83]</a></span>To these objections we would reply, first, as regards the novelty of +opinions expressed, that we have taken up the pen, because we had to +write something different from what has already been published in known +works, otherwise it would have been our duty to remain silent; and +secondly, as regards the inefficacy of inoculation, that organic and +vital phenomena have their principles and their laws, which are fixed +and invincible, from which it is reasonable to deduce consequences and +positive rules of conduct, which cannot yield to superannuated opinions +or imperfectly executed experiments. To institute experiments indeed +under the rigorous conditions of a logical and irrefutable +demonstration, is not so easy a matter as may generally be thought.</p> + +<p>For our part, the principles deduced from strict observation are the +basis on which we build, and if it so chance that we are baffled in our +experiments we vary them indefinitely; and if still we are deceived in +our hopes, we ascribe the miscarriage to our impotence, to inadequate +means, and to the defective instruments which the physical and chemical +sciences, still in their cradle as regards organic matter, <span class='pagenum'><a name="Page_84" id="Page_84">[Pg 84]</a></span>supply for +our use. Above all, we wish it to be remembered—"<i>Scribo nec ficta, nec +picta, sed quæ ratio, sensus, et experientia docent</i>."</p> +<br /> +<br /> +<br /> +<br /> + +<hr /> +<br /> +<h2>CHAPTER II.</h2> + +<p class="cen"><i>The Origin and Causes of the Ox Typhus.</i></p> +<br /> +<p class="cen">I.</p> + +<p>I have drawn my conclusions as to the preventive treatment of typhus in +the ox, from the knowledge I had acquired of its morbid phenomena, its +nature, and its non-recurrence; and it is a logical deduction quite as +accurate as could be the result of a syllogism. The study of the origin +of this typhus, and of the causes by which it is generated and spread +abroad, will supply us with additional arguments to sustain this +deduction, as well as those signs and indications which are the very +foundation of curative treatment. The description of the disease will +contribute to the same result; for the rational treatment of a distemper +can be derived only from a knowledge of all the phenomena which occasion +it, <span class='pagenum'><a name="Page_85" id="Page_85">[Pg 85]</a></span>of the functional derangements, and of the alterations observed in +bodies after death.</p> + +<p>I wish particularly to say at once, in entering upon the subject of +etiology, that the special works which treat of it contain precise +information as to the causes and origin of the typhus in horned cattle; +and that the chief organs of the press in every country—those ephemeral +encyclopædias in which unfortunately so much vital force and +intelligence are dissipated—have published articles of the highest +interest on this subject. It would be physically impossible for me to +begin again a bibliographical labour similar to the one exhibited in the +First Part, in order to afford due justice to each of these public +writers, who have met the epizootia on the confines of their country and +fought hand to hand with it. This work is not susceptible of so much +enlargement. Let it be well understood, that I claim no other merit than +that of discussing these questions of etiology, in that order and with +that common sense which fix ideas firmly in the mind—which, if I may +use the term, <i>photograph</i> them on those parts of the brain allotted to +the memory and judgment; also of <span class='pagenum'><a name="Page_86" id="Page_86">[Pg 86]</a></span>drawing from known and admitted facts +more rational and practical conclusions than those which have been +current up to the present time.</p> + +<p>Much has been already said and argued on the origin of the contagious +typhus which affects the ox; some adhering exclusively to the special +conditions observable in the breed of those oxen which are reared and +fed on the steppes of Russia and Hungary; others, more reasonably, as it +seems to us, ascribing it to the hygienic conditions generally, that is +to say, to the climate, the season, the feeding, &c., &c., amidst which +these animals are living.</p> + +<p>All these discussions upon what has been said and argued on this subject +have been very useful. For, had it been rigidly proved that the oxen of +the steppes, by some peculiar organization, carry within them those +germs or physiological elements which at given times become the leaven +of the distemper, and, at a subsequent period, the elements of the +contagion, then, indeed, a fact of capital importance and prominent +authority would have been established, and the attention of all men +interested in these inquiries would have been <span class='pagenum'><a name="Page_87" id="Page_87">[Pg 87]</a></span>exclusively concentrated +on that particular race of animals and on those countries smitten with +the curse, in order to arrest and confine the disease within its one and +only focus.</p> + +<p>The supporters of this theory, concerning the first circumscribed origin +of the typhus, maintain that all the epizootics whose deplorable history +we have given in the first part of this work, have had no other +generative causes than the propagation of the complaint, born and +begotten on the banks of the Wolga and the Danube, and subsequently +conveyed to the different parts of the earth by the emigration of the +cattle. And in this manner, too, they have accounted for the appearance +of the typhus in South America, in Africa, and in Asia.</p> + +<p>Since this doctrine on the origin of the typhus has been conceived and +maintained by men of a high order of understanding, we must suppose that +they had been struck and convinced by important facts and serious +reasons; and as it would be unfair to oppose a plain denial to an +opinion now so generally adopted, we are bound to say in what manner +these authors justify their views, after which we shall endeavour to +refute them.</p> + +<p><span class='pagenum'><a name="Page_88" id="Page_88">[Pg 88]</a></span>The partisans of the circumscribed origin, who make it depend +exclusively on the peculiar organization of the race of the steppes, +have based their argument, peremptory and unanswerable as they imagine, +on the prime fact, that it has always been possible to trace the +diffusion of the typhus in a given country, to some sick animal of the +steppes conveyed to that kingdom. In this manner it is, that they +explain the generation of the epizootics which have so frequently wasted +the continent of Europe. On whatever point of the globe they may appear, +this, and only this, is the source of their existence. The isolated +position of Great Britain is made to support their arguments. "Behold," +they exclaim, "Great Britain, which, thanks to its surrounding seas, has +escaped most of the epizootics which have desolated France and Germany +during the early part of the nineteenth century." Nay, more, the present +visitation of the distemper is also seized upon to sustain their theory, +since certain oxen, natives of the steppes, appear to have imported it +into London.</p> + +<p>We must add, that nothing is wanting in order to prove this assertion; +for they <span class='pagenum'><a name="Page_89" id="Page_89">[Pg 89]</a></span>relate with perfect regularity, and step by step, the course +taken by the contagion; they specify the time occupied on its passage, +and even the names of the infected vessels which have thus imported the +principle of the typhus.</p> + +<p>It must be admitted that all the facts thus stated are indisputable; we +acknowledge as true, that the bovine race of the steppes has conveyed +into other countries the contagious germs of the disease; we admit that +its dissemination may be thus accounted for.</p> + +<p>But to admit this fact, and to draw from it the conclusion that the +bovine race of the steppes alone is capable, by some particular and +distinct organization, of developing the original typhus of the ox, and +that this typhus has no other focus on the earth than the banks of the +Dnieper and the Don, does not appear to us a sound logical deduction. +And as, if this conclusion were positively recognised, we might see but +one side of the evil, and deduce very serious consequences therefrom, it +is necessary to receive these facts for what they are worth, and no +more.</p> + +<p>Let us first observe, that those writers who ascribe the contagious +typhus to the race of <span class='pagenum'><a name="Page_90" id="Page_90">[Pg 90]</a></span>Southern Russia, do not take into consideration +the epizootics of this typhus, the account of which has been handed down +to us by the ancient authors of Greece and Rome; and that they refer +just as little to those which are quite as frequent in the republics of +South America as on the banks of the Dnieper. For even if we allow that +once, and only once, one of these epizootics may be traced to the +arrival of a ship containing oxen brought from the steppes, how, on the +other hand, can we believe that all other epizootics have had such a +fortuitous cause to generate it; consequently, the typhus, in these +cases, must have been locally developed and diffused among American +cattle?</p> + +<p>Moreover, we seek in vain for the reasons which would authorize us to +assign to the bovine race of the steppes a particular organization, +rendering it alone fit to engender the typhus. But let us grant for a +moment, that the Russian and Hungarian oxen constitute a peculiar race, +as their framework and the length of their horns would seem to imply; +this much being conceded, it still remains to be shown in what respect +their anatomical and <span class='pagenum'><a name="Page_91" id="Page_91">[Pg 91]</a></span>physiological structure differs from that of other +animals to such an extent as to render them alone liable to originate +this fatal typhus.</p> + +<p>Oh! if it were true that the bovine race of the steppes alone could +engender the typhus! we would hail the fact with joy, and would show +without much exertion of reasoning that, in that case, we possessed not +only the means of preventing the disease by inoculating sound and +healthy cattle, but the far more important means of sweeping it for ever +from the earth, by at once exterminating that cursed race, smitten with +the original predisposition of this plague; and as, after all, the +murderous scourge of the typhus of the steppes has already cost, and may +perhaps continue to cost the various nations of the Old World millions +upon millions, they would feel that their most urgent interest would be +to come to an understanding (nor would the sacrifice be too much for +their resources) so as to destroy and extirpate the evil at its original +source. There would then be no difficulty in raising up a new breed of +cattle in those countries, by transporting to it those of other nations +free from the infection.</p> + +<p><span class='pagenum'><a name="Page_92" id="Page_92">[Pg 92]</a></span>But who does not understand that this heroic sacrifice would be +illusory, and that the foreign races, modified in time in this new +medium, would regenerate the typhus; so that the double sacrifice of +extermination and indemnity would have been made to no purpose?</p> + +<p>We wish we could adopt this hypothesis, so simple and so consolatory, of +the circumscribed origin of the typhus, and its exclusive propagation +through the race of the steppes; but our mind is altogether opposed to +that view, and for the following reasons, amongst others:—</p> + +<p>If the bovine race of the steppes alone could produce the typhic virus, +by reason of a particular organization which is the prime condition of +its existence, <i>this race alone would of necessity be fit to receive its +taint</i> by the influence of contagion. But if the other animals of the +same species, as unfortunately too surely happens, can receive the +principle of the disorder, develop the ailment, and die of its effects, +then the reasoning of our opponents is faulty from its source; and it +must be admitted that all horned cattle are apt to generate the typhic +virus in those countries <span class='pagenum'><a name="Page_93" id="Page_93">[Pg 93]</a></span>which afford the conditions of its production, +and that this exclusive predisposition as it is called, attributed to +the race inhabiting the steppes, is simply a chimera.</p> + +<p>But arguments are seldom exhausted even to defend a bad cause, and it is +objected that the fact that all oxen may contract the typhus transmitted +by the contact of animals from one to another, does not prove that the +original predisposition is the same in every race; and they persist in +maintaining—1st, that the typhus of the steppes is alone able +originally to beget the disease; 2nd, that having thus begotten and +produced it, it becomes, after this organic conception, apt to be +transmitted to every animal, and fit to be assimilated with them.</p> + +<p>To these subtleties and argumentative refinements it would be as easy +for me to oppose abstract reasonings equally strong, as it would have +been for the Jansenists and Mollinists, had it so chanced that they had +been drawn into a debate on the origin and nature of the virus of the +plague which carried off Jansenius. But let us confine ourselves to +serious facts and conclude—</p> + +<p><span class='pagenum'><a name="Page_94" id="Page_94">[Pg 94]</a></span>1st. That we have no proof of any anatomical and physiological +difference in the humours or in the blood—that is to say, in the +organic, intimate, and biological elements of the individuals which +collectively constitute the bovine species.</p> + +<p>2nd. That we have a right to believe, that all horned cattle are apt to +develop the typhic virus when they are placed within the conditions +required for that effect—that is to say, when they are exposed to the +special morbific causes which form its condition <i>sine quâ non</i>, and +which are met with on the banks of those great rivers which water +Southern Russia and Hungary, in Africa, on the banks of the Nile, in +South America, on the margins of the lakes, and in what are called hot +climates, &c.</p> +<br /> + +<p class="cen">II.</p> + +<p>But if the origin of the typhus cannot exclusively depend on the +peculiar organization of certain individuals of the bovine species, we +must inquire after and search for the real causes which produce it.</p> + +<p><span class='pagenum'><a name="Page_95" id="Page_95">[Pg 95]</a></span>We have explained already, in the First Part, what alterations organic +matter undergoes in general, when accidental causes happen to modify its +organic elements; and we have pointed out the fact, that of all living +creatures herbivorous animals were those that offered the least vital +resistance to the causes of disease and destruction.</p> + +<p>This unquestionable fact being taken for granted, let us now consider +under what conditions live the multitudinous herds of horned cattle +which in Russia and in South America are reared and supported solely for +the produce of their flesh, and sometimes, too, for that of their hides.</p> + +<p>The great breeders and proprietors fix the number of their heads of +cattle according and in proportion to the quantity of the pastures, but +like other men, they mortgage the future for their benefit without +making due allowance for accidents or extreme changes of weather, as +when years of unusual drought succeed those of heavy rain; so that these +herds, by the single fact of these extreme fluctuations in the degrees +of temperature, are exposed to a multiplicity of causes productive of +disease. The <span class='pagenum'><a name="Page_96" id="Page_96">[Pg 96]</a></span>same nature which generates life and health generates +disease and dissolution, and when the former are neglected the latter +will prevail.</p> + +<p>In the prosperous and favoured countries of the temperate zone, such as +England and France, these extreme variations in the seasons, which are +always the cause of a deficiency or alteration in the production of +fodder, are equally the cause of the numerous epizootics which attack +all the herbivorous species, and particularly those to which oxen fall +victims, such as the tumourous typhus (<i>le typhus charbonneux</i>), the +so-called aphthous fever, the contagious peripneumonia (which is not +liable to return and is prevented by inoculation), parasitical cutaneous +disease.</p> + +<p>But in less favoured countries, in those which are damp, argillaceous, +swampy, inundated by the overflows of their lakes and rivers, or by the +reflux of the sea, there is deposited a slimy or brackish water, which a +temporary torrid heat afterwards causes to ferment; and then a +superabundance of life, a teeming vegetation, springs up in all +directions. In the midst of this swarming vitality live and <span class='pagenum'><a name="Page_97" id="Page_97">[Pg 97]</a></span>thrive an +infinity of worms, maggots, animalculæ, insects, mollusca, fish, +reptiles, birds, &c.; and here, too, all these creatures die and decay, +when this slime, the prolific source of generations which we might look +upon as spontaneous, begins to dry up and disintegrate. Then from these +organic vegetable and animal matters, in a state of decomposition, +escape those deleterious gases, such as hydrogen, carbonic oxide, +nitrogen, carbonic acid, sulphuretted hydrogen, and even phosphoretted +hydrogen.</p> + +<p>Often to all these causes of infection are added myriads of +grasshoppers, which cover the ground, where they die, aggravating the +mass of pestiferous vapour which fills the atmosphere. Finally, the +water which slakes the thirst of the herds of cattle is corrupted; the +plants on which they feed distil poisons; the air, the water, and the +plants, carry within them a principle of venom and death. After this, +how can we be surprised if this flood of putrid emanations is +transformed into a contagious typhic virus, whose subtle and +pestilential effluvia are conveyed by the ox to considerable distances?</p> + +<p><span class='pagenum'><a name="Page_98" id="Page_98">[Pg 98]</a></span>In fine, let us recapitulate in our minds all the causes of destruction +to which these passive creatures are exposed, and we shall acknowledge +that there is no necessity to attribute to them a peculiar organization +in order to understand the development of the typhus, which, at a given +moment, cuts them all off; and that in the deltas of the different +countries, as well in Asia, Africa, and America, as in Europe, are to be +found those conditions of infectious disease which we have described. In +these causes, and only in these causes, or in those which resemble them, +will rational men seek for the principle of the contagious typhus in the +bovine race.</p> + +<p>Moreover, who is there who does not understand that what is true with +regard to cholera is likewise applicable to this contagious typhus? The +cholera, for causes analogous to these, subject to the particular state +of the soil, is generated, not exclusively, it is true, but most +frequently, on the banks of the Ganges, in the same manner as the +contagious typhus is developed in certain countries where its natural +focus is found.</p> + +<p>The race of animals which exists on this <span class='pagenum'><a name="Page_99" id="Page_99">[Pg 99]</a></span>deadly and destructive soil is +an instrument of incubation for typhus, not in consequence of their +peculiar structure, but because the conditions under which they live +condemn them to this fate.</p> +<br /> + +<p class="cen">III.</p> + +<p>Now the breeding of cattle, and the feeding and fattening of them for +the market, constitute a branch of industry—a great interest. They all +have to be removed, conveyed to various distances, and sold; so that +this traffic becomes a new cause to be added to all those which foster, +develop and propagate the distemper.</p> + +<p>In prosperous times, when the seasons, conformably with our wishes, have +pursued a course which we call regular (for we are fain to believe that +the planets turn on their axes on our account), and when the cattle find +the ground covered with rich pastures, and limpid streams—conditions +which are eminently favourable in themselves, though in Hungary it is +necessary to add gum, salt, mineral <span class='pagenum'><a name="Page_100" id="Page_100">[Pg 100]</a></span>water, and arsenic acid, before the +health of these animals is satisfactory,—then the cattle breeders make +their sordid calculations, and select the heads of cattle intended for +sale.</p> + +<p>With animals, as with man, health is but relative, not absolute; the +healthiest in appearance often bearing within its frame the fatal +principle of no distant death. Fatness not being by any means a sure +sign of vital strength, many of these cumbersome beasts, though +seemingly in good and sound condition, contain in their systems, in +various stages of incubation, the tainted leaven of contagious +affections, such as peripneumonia, or even the typhus itself.</p> + +<p>But, regardless of this liability, their sale and migration are resolved +upon at length. Hitherto these harmless creatures have lived in the most +perfect stillness and retirement. Their calm, monotonous life has been +as regular as the course of time; never by a single pulsation have their +hearts exceeded the wonted number per minute; they are all gifted with a +nervous sensibility of which the vulgar have no notion. Some favoured +few have <span class='pagenum'><a name="Page_101" id="Page_101">[Pg 101]</a></span>felt the sympathy of friendship for the herdsman who tended +them, and for the companions with which they fed. They have been leaders +of their own herd, they have marched at their head; they have given the +signal when to seek shelter beneath the trees, or when to repair to the +brook. They have loved the fields amidst which they have grown and +thriven. Some of them, reared and fed beneath the domestic thatch, were +grateful for the care they had received; their master was endeared to +them, they would run to meet his coming, answer to their name, and lick +his hand with fondness.</p> + +<p>And it is the course of this tranquil, this happy existence, that is +about to be broken abruptly. It is this creature, the pattern of +gentleness and goodness, that we are going to treat like a heap of +insensible and inert matter—which we are going to subject to +unutterable torture!</p> + +<p>And now, indeed, these creatures are all at once handed over to the +savage guidance, to the thongs and cudgels, of a hind, whose cruelty +keeps pace with his stolid ignorance, and who abets his dogs to quicken +their course to the <span class='pagenum'><a name="Page_102" id="Page_102">[Pg 102]</a></span>neighbouring market. From this moment, half-fed and +athirst, these poor animals are forced to make long journeys afoot; or +since the construction of railways, to be heaped together confusedly in +a locomotive pen. There, the shaking, the sudden starts, the friction of +five hundred wheels on the rails, the horrid snorting of the engines, +alarm and terrify them to such a degree as to turn the whole mass of +their blood.</p> + +<p>In such a state of vital prostration or feverish excitement, entire +herds are carried to the public markets or to annual fairs with other +animals, and nearly all sent to the shambles. But some amongst them are +reserved for another fate. The females, for instance, are set apart to +serve as milch cows; and in this manner they carry with them into the +cowsheds, wherein they are received, the taint of those contagious +distempers, the germs of which lay concealed in their frames, or which +they have contracted from the companions of their journey.</p> + +<p>Some of these heads of cattle, starting from the steppes of Russia, have +to travel five hundred miles in an open cage, less cared for and +<span class='pagenum'><a name="Page_103" id="Page_103">[Pg 103]</a></span>protected than bales of merchandise, exposed to the rain, to the heat +of the sun, to sudden changes of temperature, to cold and cutting +draughts, increased by the rapid motion of the train;—these animals, +foundered, prostrate, panting with fever and torturing pains, still have +to undergo new trials, if they cross the sea. In this case, the wretched +victims are violently expelled from the locomotive, rocking sheds of the +railway; a leathern strap hanging from a crane lifts them into the air, +and lets them down into the mid-deck of a ship, where they are crowded +as closely together as possible, for here, too, space is very costly. +Finally, the vessel gets under way and ploughs the ocean; contrary winds +beat it about in every direction, and these poor creatures have to +endure a new kind of torture, accompanied by the intolerable pangs of +sea-sickness; and in this state it is that they alight on the British +soil, and are driven off to the different markets.</p> + +<p>It is useless to expatiate at length on the state of general derangement +and disease in which these oxen reach their final destination. Some +amongst them have endured for eight or <span class='pagenum'><a name="Page_104" id="Page_104">[Pg 104]</a></span>nine days these unspeakable +tortures, without being sustained by nourishment—for no animal, when +his spirits forsake him, can assimilate his food amidst all this +physical suffering and so great a shock to his nervous system.</p> + +<p>Let us here declare that these animals, though removed from their +meadows with all the signs and appearances of sound health, at a time +when a fine season had been productive of abundance, and when no +epizootia was raging in the country which they have left, may +nevertheless bear within them the taint of contagious typhus; and let us +ask ourselves what must come to pass in those disastrous years when this +typhus prevails under the influence of those destructive causes which +were passed in review just now, and when the Russian and Hungarian +proprietors, eager to forestall an inevitable general calamity, hasten +to send off to Italy, France, Holland, Finland, or to the ports of +England, many animals already seized with typhus, and whose virus must +have acquired infectious properties still more intense and deadly under +the influence of the deep disquiet and commotion which the removal <span class='pagenum'><a name="Page_105" id="Page_105">[Pg 105]</a></span>and +conveyance of these animals, under conditions so deplorable, must have +produced in their frames.</p> + +<p>Such are indeed the pernicious conditions in which oxen may be, and +often are, dispatched to England; and such appears to be the real cause +of the outbreak of the spreading epizootia which we witness at this +moment, and which has created so much alarm in so many counties of +England.<a name="FNanchor_B_2" id="FNanchor_B_2"></a><a href="#Footnote_B_2" class="fnanchor">[B]</a></p> +<br /> + +<p class="cen">IV.</p> + +<p>Let us now consider this contagious typhus in its destructive extension +over the British soil; let us study and examine the causes <span class='pagenum'><a name="Page_106" id="Page_106">[Pg 106]</a></span>of its +diffusion as they pass under our notice.</p> + +<p>The mooted question of determining whether the cattle typhus was +originally imported from abroad, or whether it broke out spontaneously +in England, has been, and still is, a subject of dubious debate amongst +some professional men, amongst the leading writers of the public +journals, and also amongst agriculturists and farmers.<a name="FNanchor_C_3" id="FNanchor_C_3"></a><a href="#Footnote_C_3" class="fnanchor">[C]</a></p> + +<p>And, in truth, the propagation of the distemper is occasionally +witnessed under conditions so singular and striking, that it seems to +warrant and supply arguments for every conceivable opinion.</p> + +<p>When the disease was recognised and identified for the first time on the +24th of June, 1865, public opinion ascribed its appearance to contagion +arising from some diseased cows imported from Finland, and which, after +being exposed in the Islington Market on the 19th, were sold and removed +to the cowsheds of a breeder or dairyman.</p> + +<p>We may observe that, on hearing the intelligence of this sudden +invasion, the public <span class='pagenum'><a name="Page_107" id="Page_107">[Pg 107]</a></span>mind, which is so excitable in England, did not +disguise the indignation it felt against foreign countries which had +been capable of contaminating an island so advantageously situated and +so well protected, and infecting her magnificent herds, exuberant with +health. But after a closer examination of the facts, and possibly +alarmed, at the serious consequences of a Continental blockade which +would deprive the United Kingdom, not of the entire twenty or thirty +thousand live stock, such as oxen, sheep, pigs, &c., which they receive +every week, but only of the eight or ten thousand head of cattle which +are landed weekly on their coasts to supply their markets, public +opinion was appeased. But, unfortunately, this national susceptibility +now took the opposite extreme; and the only causes it now saw were the +dirt and want of adequate ventilation in the metropolitan stables and +sheds; and to these causes it attributed, first the generation, and then +the propagation or diffusion of the malady; an opinion which appeared +all the more natural and reasonable, in that the oxen and cows of the +graziers were the first victims of the typhus.</p> + +<p>We all know how liable, among all nations, <span class='pagenum'><a name="Page_108" id="Page_108">[Pg 108]</a></span>the public mind is to waver +and fluctuate, and how susceptible and open it is to new impressions +during fatal visitations and general calamities; nor can we feel the +least surprise at the uncertainty which has so long prevailed, and still +continues, as to the real causes of the introduction of the bovine +typhus in England.</p> + +<p>Let us therefore examine this question of etiology, and try to discover +what opinion ought to prevail.</p> + +<p>It is important to establish at once two material facts which seem to us +indisputable:</p> + +<p>1st. That the contagious typhus in cattle which is known to be permanent +in the southeast of Europe, actually existed there during the month of +June, 1865; 2nd, That some of the horned cattle, fed and reared in that +part of Europe, were transported to England, after having crossed +through Russia from south to north, in order to avoid passing through +Germany.</p> + +<p>As for the first of these facts, it is admitted and received, as might +easily be proved by reproducing the speeches and addresses delivered by +the veterinary doctors at the Congress now being held at Vienna, and at +which were <span class='pagenum'><a name="Page_109" id="Page_109">[Pg 109]</a></span>present the men whose experience of this cattle distemper +gives them the highest authority—Hertwig, Jessen, Röll, Siegmund, +Gerlach, &c.</p> + +<p>The contagious typhus of horned cattle is so fully in the epizootic +state in those countries which are washed by the Black Sea, that it was +enough for the veterinarians present at the Congress to manifest a +desire to see cattle afflicted with this disease, for the opportunity so +to do to be immediately afforded them.<a name="FNanchor_D_4" id="FNanchor_D_4"></a><a href="#Footnote_D_4" class="fnanchor">[D]</a></p> + +<p>Thus, then, the fact is undeniable, the contagious typhus was raging, in +June, 1865, in Hungary and Russia, as it rages there at all times.</p> + +<p>As for the conveyance of cattle from those countries into England, the +fact is no less certain and assured. It is well known that a convoy of +300 heads of cattle, proceeding from the pasture-grounds of Hungary and +Austria, was transported into Finland by rail, and afterwards shipped at +Revel for England. Thanks to the rapid locomotion by steam, the +migration of these cattle had lasted but ten days—two days for the +transport by land, <span class='pagenum'><a name="Page_110" id="Page_110">[Pg 110]</a></span>and eight days for the passage by sea, through the +tortuous line of the Baltic; but this was sufficient length of time for +the incubation to be produced, even supposing the animals to have looked +sound when their transit began.</p> + +<p>Moreover, it is indubitable that the markets of this immeasurable London +have for many years been supplied with horned cattle from every country: +from France, Holland, Belgium, Podolia, Poland, Prussia, Austria, +Hungary, and Russia.</p> + +<p>Thus, the Islington Market (the fact is assured) had received horned +cattle imported from the countries where typhus is known to be +permanent. Were these cattle thus imported affected with the typhus? +This fact likewise is as certain as the other, since two of the foreign +cows thus imported, were the first to fall sick, and to die of this +typhus.</p> + +<p>But if the contagious typhus of horned cattle rages permanently on the +banks of the streams which discharge themselves into the Black Sea, and +if the beasts reared in those countries have long been transported to +<span class='pagenum'><a name="Page_111" id="Page_111">[Pg 111]</a></span>England and other countries, how, it will be asked, is it that the +disease has not broken out more frequently, for it has never been seen +in Great Britain, at least, during the former part of the nineteenth +century?</p> + +<p>This question is not devoid of a certain degree of importance, and +deserves to fix our attention for a moment.</p> + +<p>Now the conditions in which the animals were exhibited in 1863 and 1864 +were precisely the same as those of 1865, before the outbreak of the +disease; and yet the contagion has been possible in 1865, whilst it was +not so in 1863.</p> + +<p>We do not presume to explain the mysterious phenomena which govern the +development of epidemics and epizootics; but it seems to us not +altogether impossible to give a rational and satisfactory elucidation of +the facts.</p> + +<p>In general, in <i>epizootics</i>, and I might even say in some particular +epidemics—in that of the typhus, for instance—three connected and +inseparable facts form the condition <i>sine quâ non</i>, of the generation +of the disease. First, a focus for producing the virus; secondly, for +<span class='pagenum'><a name="Page_112" id="Page_112">[Pg 112]</a></span>the most part a favourable soil, and a special predisposition amongst +animals to receive and propagate it; thirdly, what is called an epidemic +or epizootic genius—that is to say, a particular state of the +atmospheric elements, or the air, which hitherto has escaped our +analyses, and whose morbific properties vary in their degrees of +intensity. Thus the epizootic genius of 1711, the terrible one of 1750, +and the one which now diffuses its contagious miasma, have differed in +some of their virulent conditions.</p> + +<p>However that may be, it will be sufficient to glance back at the past to +assure ourselves that, in general, epizootics have been coincident with +some violent change of season, such as extreme droughts, or +superabundant rains; that is to say, when the cattle, disturbed in the +physiological conditions of their health, have become favourable to the +incubation of the miasmatic leaven scattered through the air, or else +when these animals were living under irregular conditions, and had to +endure unwonted fatigues and privations, as in the folds of campaigning +armies, for instance.</p> + +<p>These epizootics have appeared to depend <span class='pagenum'><a name="Page_113" id="Page_113">[Pg 113]</a></span>not only on the state of the +soil and of the health of the cattle, but also (we repeat it designedly) +on an element no less indispensable to the propagation of the disease—a +special state of the air, which favours the development and preservation +of typhic miasma: for sometimes a sudden change of temperature has +proved sufficient to stop the rampant progress of the contagion, the +other conditions remaining unaltered.</p> + +<p>These relations of cause and effect between the contagious principle, +the predisposition of the animals, and the state of the atmosphere, +evidently are subject to some exceptions; but we must allow that in the +present epizootic they are absolutely and completely applicable. For, in +truth, the years 1864 and 1865 have been distinguished, if not by the +persistency of a high rate of temperature not often witnessed, at least +by an excessive drought during the months which are both hot and rainy; +and this has happened in the various countries of Europe, thereby +producing a falling off in the pasture and fodder both as respects their +quantity and quality.</p> + +<p>As to England, a country usually cold and <span class='pagenum'><a name="Page_114" id="Page_114">[Pg 114]</a></span>damp, but renowned for its +spacious green fields and meadows, it has suffered more than any other +country from these unfavourable conditions, and their destructive +influence on the grass and corn; the herds having found a great +reduction of food where formerly they met with abundance. Everybody has +seen, as we have ourselves, large herds of cattle, wandering in +amazement from field to field, and seeking for something to browse on a +parched and arid soil. A supplementary provision of corn, roots, malt, +and the grounds of the beer vat or spirit barrel, no doubt served to +mitigate the sad effects of these privations on the health of cattle; +but in spite of all that could be done, their blood became impoverished, +their strength and vital resistance sank, and (like the animals which we +transferred at will into a soil more favourable to the spread of +parasitic diseases), they afforded last June, as they do now, an unusual +predisposition to suffer and transform the morbific principles of +typhus, which in all probability they would have been proof against at +any other time. We may very fairly infer this much, for we must of +necessity believe that the regular importation <span class='pagenum'><a name="Page_115" id="Page_115">[Pg 115]</a></span>of cattle from those +countries which are considered as the permanent focus of typhus, has +from time to time transported the miasmatic germs of this malady into +England, although the virus did not take effect on British cattle at +those periods, for want of one or other of the conditions necessary to +its generation and development.</p> + +<p>We may likewise infer, and a watchful appreciation of the facts +contained in the veterinary medical journals would show that this +opinion is not unfounded, that the special disease which constitutes +this typhus (similar in that respect to epidemic diseases), may develop +itself in one beast by accident, spontaneously, sporadically—that is to +say, without immediate contagion; in a word, <i>apart from those epizootic +conditions which alone render its propagation possible</i>. To be brief, we +think that an isolated case of cattle typhus may by chance be detected, +when there is no epizootia prevailing to account for it, just as we +occasionally meet with cases of typhus or cholera among men during +seasons absolutely free from these epidemics. It would not, therefore, +appear to us altogether impossible, that under the <span class='pagenum'><a name="Page_116" id="Page_116">[Pg 116]</a></span>influence of very +special conditions, the contagious typhus of the ox might have its birth +in England; and this would favour the theory of those reasoners who +maintain that this typhus met with the first causes, and the origin of +its development, in the stalls and cowsheds of London. But such has not +been the cause of cattle typhus in the epizootia which we see at +present.</p> + +<p>No doubt some animals suffered great privations, but, whatever +alteration their health may have sustained, all this is nothing to be +compared to the sufferings endured by the cattle in the steppes under +the influence of deleterious conditions of the most exceptional +character, which do, indeed, give birth to this typhus, and which we +have already described.</p> + +<p>No, certainly not! <i>Nothing authorizes us to believe that the typhus now +under our observation was bred and born, at first, within the stalls and +cowsheds of London.</i> It was most assuredly imported. But it is true, +nevertheless, that this cruel scourge found the horned cattle of England +predisposed to receive it, and it likewise met with atmospheric +conditions <span class='pagenum'><a name="Page_117" id="Page_117">[Pg 117]</a></span>favourable to its subsequent diffusion; in a word, it met +with the epizootic genius proper for the generation and propagation of +the typhus miasma.</p> + +<p>It is thus that we may account for and reconcile the two contending +theories, one of which refers the cause of this typhus to foreign +importation, whilst the other insists that it originated in the filthy +and half-ventilated cowsheds of the metropolis.</p> + +<p>But if this typhus could not spring up spontaneously out of the bovine +race of England, it must be confessed that, independently of the general +predisposition due to a great and protracted drought, it found in the +sickening sheds of the metropolitan and country cattle the most +favourable conditions for its incubation and subsequent diffusion.</p> + +<p>It would, indeed, be difficult to conceive of anything more directly +adverse to the hygienic laws of health in cattle than the stalls and +sheds dotted over the densely populated districts of London. Most of +these pent-up cribs are situated in narrow lanes and yards, in filthy +streets and blind alleys; and within these close, hot, and steaming +receptacles the <span class='pagenum'><a name="Page_118" id="Page_118">[Pg 118]</a></span>miserable cows, pressed against each other, without +ever moving a limb, waste away and become phthisical in a very short +space of time. We may readily imagine what a prey to the contagion must +be afforded by these animals, already more or less ailing, some of which +are fed in a great measure on malt, so sour and acrid that the very +smell of it is intolerable. The milk from these cows is, moreover, of so +wretched a quality, that in a cowhouse containing 48 of these poor +creatures, at Kensington, I found only one, the milk of which exhibited +the taste and quality fit for a sick child, for whom I ordered a milk +diet.</p> + +<p>It is not, therefore, to be wondered at that the present epizootia, +during this late tropical season<a name="FNanchor_E_5" id="FNanchor_E_5"></a><a href="#Footnote_E_5" class="fnanchor">[E]</a> especially, should have met with all +the conditions most conducive to its development and propagation.</p> + +<p>When the cattle distemper first broke out, the graziers, not suspecting +its gravity, attempted to treat the animals themselves, but soon +afterwards perceiving the fruitlessness of all their remedial measures, +they felt that the <span class='pagenum'><a name="Page_119" id="Page_119">[Pg 119]</a></span>best thing they could do was to turn their sick +beasts to whatever account they could, by driving them to market or to +the slaughter-houses, an expedient which they were the more disposed to +adopt, inasmuch as the diseased cows had ceased to give milk. And then, +the removal of these animals, in various stages of the disorder, became +the most rapid means of disseminating the contagion, which, had it been +concentrated and pent-up at first within its narrow focus, would +otherwise have spread with less fearful havoc.<a name="FNanchor_F_6" id="FNanchor_F_6"></a><a href="#Footnote_F_6" class="fnanchor">[F]</a></p> + +<p>In the meanwhile the sick cows being commingled with thousands of heads +of cattle exposed for sale at the different markets, communicated far +and wide the principle of the disease; and as a certain number of these +animals remaining unsold were driven back to the farms, into stalls +until then removed from every cause of contagion, they introduced among +their sound companions the fatal germs of the distemper; and as, again, +this effectual means of propagating the evil was repeated several times +in the same week, the consequence was that, by the end of July—a little +<span class='pagenum'><a name="Page_120" id="Page_120">[Pg 120]</a></span>more than a month after the outbreak—the whole of the south of England +was in some sort contaminated. Thence the contagion extended to the +north of the kingdom, and passed into Scotland; so that, at present, the +cattle-typhus has spread its ramifications over a great number of the +counties of Great Britain.<a name="FNanchor_G_7" id="FNanchor_G_7"></a><a href="#Footnote_G_7" class="fnanchor">[G]</a></p> + +<p>In the first instance, the contagion spread from animal to animal by +means of an infecting influence in some degree direct, among cattle +sheltered beneath the same roof, or collected in swarms within the same +markets. But very soon the air itself was impregnated and polluted by +the vaporization and diffusion of the typhic miasma; and herds of cattle +which had no contact, either direct or indirect, with infected animals, +were seen to be tainted with the distemper. Whether this contamination +was produced by the passage of attainted cattle along the public roads +(having fields on the right and left), or otherwise, nothing but an +absolute isolation, an utter impossibility of contact, appeared to offer +a perfect immunity against the spread of the evil.</p> + +<p><span class='pagenum'><a name="Page_121" id="Page_121">[Pg 121]</a></span>The miasma, condensed by the fogs and transported in all directions by +the winds, now began to overleap every natural or artificial barrier, +and the favoured herds, ruminating at their ease in the manorial farms +of the wealthy patricians, in their well-kept parks and amid every +luxury, were suddenly smitten with an evil which in their case seemed an +anomaly. In such peaceful homes these innocent creatures were tended by +intelligent and benevolent hands, which understood and felt for their +frail constitutions; food of the best quality was lavishly supplied to +them, and whatever they could wish for lay around them in abundance; +richly reared, they had themselves become so many ornaments within these +scenes of beauty, and all men thought that here, at least, were plots of +rural ground which the genius of epizootia would not invade, and in +which the healthy herds were invulnerable to contagion.</p> + +<p>It was under these circumstances that the fine farms of Earl Granville, +at Golder's Green, skirting the Finchley Road,<a name="FNanchor_H_8" id="FNanchor_H_8"></a><a href="#Footnote_H_8" class="fnanchor">[H]</a> containing as many as +130 milch cows, were suddenly and <span class='pagenum'><a name="Page_122" id="Page_122">[Pg 122]</a></span>fiercely attacked amidst their +seeming immunity, and struck down in great numbers.</p> + +<p>"When I left England a month ago," said the noble lord, "there were +about 130 milch cows in four sheds; in the two largest and best managed +I found only one cow yesterday, September 4th."</p> + +<p>The park of Holly Lodge,<a name="FNanchor_I_9" id="FNanchor_I_9"></a><a href="#Footnote_I_9" class="fnanchor">[I]</a> which is partly bounded by the main road +along which pass and repass files of cattle going to and coming from the +markets, was visited by the same unsparing scourge. Now certainly, the +noble and beneficent lady of the manor, who secured to her cattle every +attention, and who, confiding in the resources of medical science, +attempted every means to save these stricken creatures doomed to an +inevitable death; she whose enlightened mind, equally open to the claims +of science as to those of misfortune, desired that experiments should be +made which might tend to throw any light on this devastating malady; +she, at any rate, one would think, might have escaped the common lot +without exciting wonder or envy at the privilege which she enjoyed. But +this fell <span class='pagenum'><a name="Page_123" id="Page_123">[Pg 123]</a></span>and sweeping epizootia, inexorable in its latitudinarian +march, entered those shady bounds, and decimated those orderly sheds +with the same impartiality as it did that of the poor man, Cutting, +whose whole fortune was stored up in the two milch cows whose death he +had to deplore.</p> + +<p>This epizootia threatens to invade, one by one, all the European States, +like the awful scourge of 1750, to which we have already drawn +attention. For even now Holland and Belgium<a name="FNanchor_J_10" id="FNanchor_J_10"></a><a href="#Footnote_J_10" class="fnanchor">[J]</a> have been smitten; and +the alarm it has excited has for a time superseded the panic which the +stealthy advance of the cholera to the west had kindled. Some imagine +that it might have been kept out of Great Britain, or have been checked +in its outbreak. But, in spite of all the safest precautions and the +soundest measures of preparation, it would most likely have baffled +human skill, and neither been held aloof nor stifled in its focus. But +how painful it is, to have to write and to think that ignorance, +carelessness, revolting cupidity, and the most wanton violation of the +laws, have all contributed to <span class='pagenum'><a name="Page_124" id="Page_124">[Pg 124]</a></span>extend the evil, with the foulest +premeditation and the blindest disregard!</p> + +<p>To feel one's self a stranger in a country, and to be able to rejoice at +one's connexions with it, and at the same time to be obliged to give +publicity to certain truths distasteful to those to whom they are told, +is a most painful task. But, as it would be to swerve from that duty and +loyalty which the national interests as well as those of science impose +upon a writer, not to speak out with impartial justice in a matter of so +vital an importance, we beg permission to consider, without reserve, +this delicate question:—the causes which have contributed to propagate +the complaint.</p> +<br /> + +<p class="cen">V.</p> + +<p>England, so long spared by that wasting scourge, which had so often +extended its ravages over France and other kingdoms during the last +sixty years, was taken by surprise; and the regulations and laws +necessary to stifle without delay the distemper in its focus—that is to +say, in the metropolis—not being <span class='pagenum'><a name="Page_125" id="Page_125">[Pg 125]</a></span>in readiness, the outbreak of the +disease found her helpless and unarmed.</p> + +<p>On the other hand, the organic forms of the English Government and +municipal bodies, the reserve of the Cabinet during the vacation, the +limited power of the Lord Mayor and his civic counsellors, the +subdivision of London into parishes and vestries, as in the good times +of the middle ages, the loose scattering of the shambles and meat +markets through the many streets of the huge town, the right asserted by +each man to be absolutely independent and free, the sanctity of the +Englishman's home, &c., &c., all concurred to let loose and propagate +the contagion, instead of keeping it within bounds.</p> + +<p>Indeed, whilst the competent authorities, with all the energy which +could be expected of them on so grave a matter, were meeting and +discussing the best measures to be taken, and the interesting debates at +the Mansion-house were throwing the first light upon the question, the +insidious malady pursued its destructive progress, diffusing new terror +and alarm. When at length the Privy <span class='pagenum'><a name="Page_126" id="Page_126">[Pg 126]</a></span>Council issued their orders, +prescribing the public declaration of sick cattle, and that no affected +beast was to be conveyed either by rail or by ship, whilst all the +necessary means of purification and disinfection were to be employed, +&c., it was unfortunately too late, the dreadful calamity having taken +root and multiplied its stem like the upas-tree.</p> + +<p>What a field for reflection there is in these cases, which originating +with the imperfect state of the laws and institutions, have fostered and +encouraged the disease! But this is a subject which it would not behove +us to discuss, and we prefer to show by the notes which will be found +appended to the end of this work, and which are produced as attesting +documents, that cattle proprietors, by their own confession, too often +sacrifice the interests of the public to their own private advantage.<a name="FNanchor_K_11" id="FNanchor_K_11"></a><a href="#Footnote_K_11" class="fnanchor">[K]</a></p> + +<p>Nor have we been able to participate in the thoughts and reflections of +so many sensible and judicious persons, on the impotence and +dilatoriness of the public authorities, and also, let us say, on the +inadequate pecuniary means <span class='pagenum'><a name="Page_127" id="Page_127">[Pg 127]</a></span>proposed by a people so lavish of its wealth +when useful and great undertakings are designed, without paying a +natural tribute of regret, to the memory of a Prince who took so deep an +interest in the progress of agriculture, and who, had he still been +living, would have known how to direct with a firm and steady hand, the +right measures to be taken amidst so many intricacies and +embarrassments.</p> + +<p>Sometimes allusion has been made to France in the speeches delivered at +these meetings, presided over by that active magistrate, the Lord Mayor. +In the course of these remarks the speakers have praised and held up to +admiration the advantages of her system of centralization, the decrees +of her sanitary police, and the promptness with which she executes the +measures which the public interests require. That is true. France is +certainly in a state to resist the scourge with very effectual means to +arrest its progress; but if in this matter, as in some others, she have +acquired a superiority, it has only been by an experience dearly +purchased, these epizootics having returned more than once to destroy +her flocks and herds. Politically, the same might be <span class='pagenum'><a name="Page_128" id="Page_128">[Pg 128]</a></span>said of her +revolutions, those great moral epidemics.</p> + +<p>An orator, a writer, went so far as to say, in one of his numerous +letters, the one dated the 24th of August: "I regret to say some of our +neighbours laugh at our expense."<a name="FNanchor_L_12" id="FNanchor_L_12"></a><a href="#Footnote_L_12" class="fnanchor">[L]</a></p> + +<p>No, your neighbours will not laugh at your misfortunes. They sympathize +at present both in your joys and sorrows, and if I have taken up my pen +on this occasion, it has only been because I could not look with +indifference on your too just anxieties, when I flattered myself that I +might write some useful pages to mitigate and relieve them.</p> + +<p>As most newspaper readers are aware,<a name="FNanchor_M_13" id="FNanchor_M_13"></a><a href="#Footnote_M_13" class="fnanchor">[M]</a> and as everybody may easily +ascertain, the diseased cattle, in spite of reiterated orders to destroy +them immediately, were, nevertheless, driven to the markets to be sold +for what could be got for them; or when their tainted condition was too +glaring they were at once sent off to the private shambles, the owners +of which, in order to disguise the accusatory proof of the misdemeanor, +hastened to sell the body of the animal. It would be quite impossible to +<span class='pagenum'><a name="Page_129" id="Page_129">[Pg 129]</a></span>mention all the violations of the law, which every day continue to fill +the columns of the public journals. One graceless wretch, who deserved +to be hanged for it, if his ignorance do not excuse him, was so infamous +as to introduce a sick cow into a shed not yet attainted, in his +criminal desire of propagating the disease there.<a name="FNanchor_N_14" id="FNanchor_N_14"></a><a href="#Footnote_N_14" class="fnanchor">[N]</a></p> + +<p>Thus, then, independently of the causes inherent to the typhus itself, +which served of necessity to diffuse it, other causes proceeding from +the defective state of the law, and the perfidy of individuals, have +contributed to its dissemination. And yet the Government circulars, the +newspapers, and the reports of veterinary doctors have made known that +the slightest omissions and inattentions were serious—that the want of +ventilation and cleanliness in the stables, the overcrowding of the +cattle, and their abiding near their own droppings, or dung-heaps—that +the keeping of dead bodies close to farms, cowsheds, enclosed grounds, +and fields—that the hasty and imperfect burial of cattle—that the +collection and transit of their fragments, bones, horns, and skins—that +the driving on the public roads of <span class='pagenum'><a name="Page_130" id="Page_130">[Pg 130]</a></span>any animal either tainted itself, or +having lived among those that were sick—that the clothes of persons and +stable utensils, soiled with putrid liquids—that all these, and similar +causes, were capable of propagating or aggravating the disease.</p> + +<p>But whilst we must loudly condemn the voluntary misdeeds of those who +drove their sick cattle to market, it must likewise be allowed that, to +conform one's self rigidly to the given injunctions, was sometimes +attended with serious embarrassments. How great, indeed, must have been +the perplexity of any grazier who, being the owner, for instance, of +forty head of cattle, and having seen ten of them perish under his eyes, +without knowing where to dispose of them, was threatened with the loss +of the remaining thirty within a few days! How could he calmly and +patiently resign himself to suffer so large a quantity of animal matter +to accumulate and putrefy around him, when, suddenly ruined, and +destitute of every resource, the authorities held back instead of coming +to his assistance.</p> + +<p>The prime cause of all the transgressions committed in despite of the +Privy Council's <span class='pagenum'><a name="Page_131" id="Page_131">[Pg 131]</a></span>orders, may therefore be referred in part to the want +of compensation to be granted to the owners of infected cattle. It all +might be almost reduced to a question of money. For let us suppose for a +moment, that inspectors entrusted with adequate powers, had been +authorized, after a close examination, to point out the tainted cattle; +to fix a moderate price on them by way of compensation; to have them +slaughtered, carried away, and immediately buried, would not such a +course have diminished the generation of contagious miasma in a +considerable proportion?</p> + +<p>Moreover, some cattle-breeders and farmers exposed themselves to the +imposition of fines and penalties without any evil designs; for when +they drove their beasts to market they were only in the stage of +incubation, at the preliminary period, when it is really no easy task to +distinguish the distemper. The following fact will exemplify this.</p> + +<p>At each market, in spite of continual warnings, the inspectors pick out +and despatch to the slaughter-houses a certain number of sick cattle, +not only those affected with typhus, but with other disorders. One +cannot help <span class='pagenum'><a name="Page_132" id="Page_132">[Pg 132]</a></span>wondering, on seeing the poor, lean, sickly condition of +some of these creatures, how their owners could have been so mad as to +expose them for sale; but in their number there are a few which, +although sick, appear in good health to the common observer.</p> + +<p>About a fortnight ago, during one of our visits to the great +Metropolitan Market, Mr. Tegg, the veterinary inspector, whose +intelligence and earnestness are quite equal to the very difficult +charge with which he is entrusted, ordered to be seized and removed to a +secluded fold near the slaughter-houses, a dozen diseased animals. When +once these cattle had been thus collected in a body, it was easy to +submit them to a still closer examination. Most of these beasts, adult +cows and oxen, were lean, panting, feverish, dispirited, and remained +motionless where they stood. But among them was a cow, with a brisk and +lively look, a quick open eye, which watched us with anxiety, and fled +at our approach every time we passed by her. The turn came for this cow +to be examined. Mr. Tegg, strong and handy—as every good veterinary +doctor should be—seized hold of one of her horns, but he <span class='pagenum'><a name="Page_133" id="Page_133">[Pg 133]</a></span>was quickly +shaken off; other persons came up to assist him; the fiery animal was +suddenly seized by both horns, by the nostrils, and the tail; but so +strong and spirited was the animal, that she defended herself with +advantage against all her adversaries, and once more shook herself free.</p> + +<p>It was necessary, however, to master the creature, so they surrounded +her again, pressing her back this time into a corner of the pen, to +overpower her. But lo! the animal takes a sudden spring, and leaps over +the bars. Assuredly this cow, for a beast suspected of the typhus taint, +had given a proof, if not of health, at least of extraordinary vigour; +and her owner, who had seen her condemned with much vexation, now +thought he saw ample reason to reclaim her, and drive her back to the +market for sale. However the cow, on taking such a leap, and under +conditions so unfavourable, came down with all her weight upon her +limbs, fracturing one of her forelegs.</p> + +<p>After this accident, we were able to prosecute the examination we +desired, and Mr. Tegg showed us a row of little glandular swellings on +the ridge of the gums, and livid spots on <span class='pagenum'><a name="Page_134" id="Page_134">[Pg 134]</a></span>the vaginal mucous membrane, +which confirmed his diagnosis. The owner of this cow, nevertheless, +still discredited the diseased state of the beast; so to convince him, +she was driven off at once to the slaughter-house to be struck down; +but, unfortunately, three or four others filled the required area, so +that the poor cow was forced to witness the execution of her +fellow-creatures before being killed herself. The look and posture of +this cow, her excited yet terrified glance as she surveyed this scene of +carnage, was one of those pictures which no pencil could draw; and +although we acknowledge that man possesses an incontestable right to +apply to his own use the dead or live matter of animals for his food and +sustenance, we could not help feeling for the poor victim, slipping over +the blood, and thus scenting death before receiving the stroke.</p> + +<p>We are not excessively sensitive; we have seen a hundred horses bleeding +from the incisions made by veterinary pupils, and scores of oxen +slaughtered; we ourselves have practised numerous experiments on +animals; but the affecting sight of that animal witnessing the slaughter +of others, and waiting her turn to <span class='pagenum'><a name="Page_135" id="Page_135">[Pg 135]</a></span>die, touched us deeply. We could not +help asking ourselves, how it was that man could dispense with +compassion and good feeling even in that bloody toil, and why he did not +bandage the eyes of the doomed creatures he was going to sacrifice? +These dumb animals that we treat like inert matter are sensitive like +ourselves; they are very conscious of pain; and if it be our privilege +to compute the number of our days, we ought not to forget that they are, +like us, endowed with intelligence, so that when they are thus detained +at the place of execution, all their senses and faculties being +concentrated on their destroyer, they are fully conscious of the cruel +fate which awaits them.</p> + +<p>At last it was the poor beast's turn to be slaughtered, and ten minutes +afterwards we opened her entrails, and had proof that Mr. Tegg's +judgment was exact, for already the stomach and intestines offered to +view indubitable signs of the typhus at its first period.</p> + +<p>The owner of the cow was then convinced and brought to reason, but he +still very fairly asserted the goodness of his motives, about which none +present doubted at all, and applied <span class='pagenum'><a name="Page_136" id="Page_136">[Pg 136]</a></span>for compensation to the full value +of the beast, both as butcher's meat and offal, which application was +granted.</p> + +<p>Judge, therefore, by this particular example, how many tainted cattle +there must have been which have propagated this distemper, some with and +some without the knowledge of their owners; and, "<i>horresco referens!</i>" +how much of this tainted meat must have been purchased and eaten by the +public, since this cow had all the appearance of health and vigour, and +the real diseased condition might not have been detected at all, but for +the experience and sagacity of Mr. Tegg, the inspector.</p> +<br /> + +<p class="cen">VI.</p> + +<p>In this consideration of the causes of the contagious typhus in bovine +cattle, we have deemed it essential to invite attention both to those +which are generally recognised and admitted, and to those which, though +they may have been settled in the minds of observant and experienced +men, may yet appear hypothetical to certain readers.</p> + +<p>Besides which, in every scientific work, allowance must be made for the +past and <span class='pagenum'><a name="Page_137" id="Page_137">[Pg 137]</a></span>future; and here we have two vital distinctions. If the man +who undertakes this task does not go on, he falls back; and it was to +avoid incurring this reproach that we have passed our old boundaries and +visited new avenues. We are aware that more than one objection might be +urged against the opinions and theories which we have exposed, in order +to account for the outbreak of typhus in England; we might anticipate, +we might reply to these objections; but we would rather recapitulate our +inquiry into the causes, in the tangible form of practical propositions.</p> + +<p>From the general considerations above given, we think we may conclude,</p> + +<p>1st. That the causes which generate the cattle typhus on our globe are +permanent and unceasing, not only on the banks of the great rivers which +empty themselves into the Black Sea, but also in other countries—in +America, in Africa, &c.; wherever, in a word, exist the conditions, not +of race (the race of the animal in this case being but secondary), but +of climate and of the organic elements which are indispensable to the +formation and development of typhic miasma.</p> + +<p><span class='pagenum'><a name="Page_138" id="Page_138">[Pg 138]</a></span>2nd. That the cattle typhus, although it exists not necessarily, but +through the improvidence or want of caution in man, on different parts +of the earth, never appears at all in the temperate and more genial +zones, save under particular and special circumstances, analogous in +some degree with those which generate the human typhus—inclemency of +the seasons, overcrowded dwellings, bad or insufficient food, and want +of cleanliness; and that these particular and special circumstances give +birth to the epizootic genus, rendering the cattle fit and apt to +receive the germs of the contagious virus, and to foster its incubation.</p> + +<p>3rd. That the cattle typhus, thus accidentally developed in the +temperate and genial zones, by means of the vicious hygienic conditions +amidst which horned cattle are accustomed to live, and which serve as +the causes of its propagation, is afterwards transmitted by the contact +of animals living in the same stall or shed, or collected in herds on +the same ground, or transported in the same vehicles, by land or sea.</p> + +<p>4th. That the droppings of animals, their litter, their dead bodies, and +their detritus, or <span class='pagenum'><a name="Page_139" id="Page_139">[Pg 139]</a></span>broken-up remains—also the stables, vehicles, and +implements which have served for their use, and all matters or +substances which have touched them or approached them—are generative +elements of the distemper.</p> + +<p>5th. That the typhic miasma, thus reproduced and multiplied in one place +under the influence of all these producing causes, is conveyed by the +winds to great distances, smiting those well guarded cattle which +appeared to be fully protected from the possibility of infection by +their isolation.</p> + +<p>6th. That the want of prompt and stringent measures first to +concentrate, and then to stifle this typhus in its focus; the love of +lucre, the perfidy of some, and the absence of foresight and caution in +others, may be, and have been in the particular cases which we are +dealing with, material causes and agencies of its diffusion.</p> + +<p>Such we consider to be the causes which engender and propagate cattle +typhus, and which will serve as a basis for the preventive measures to +be employed in order to withstand and check its propagation.</p> + +<h4>FOOTNOTES:</h4> + +<div class="footnote"><p class="noin"><a name="Footnote_B_2" id="Footnote_B_2"></a><a href="#FNanchor_B_2"><span class="label">[B]</span></a> We are aware that the transport of cattle is conducted in a +different manner during the prevalence of this epizootia. The account +given by two German veterinary surgeons of the management of the vessels +of the North German Lloyd's, and of the manner in which the animals are +treated, is a proof of this; but before the appearance of the epizootia, +the transport of animals by land and by sea left much to be desired. +This account will be found at the end of this work (<span class="smcap">Note A</span>); +and all documents in support of the facts which have served as the basis +of our dissertation, are also in the Appendix, arranged alphabetically +in the form of notes.</p></div> + +<div class="footnote"><p class="noin"><a name="Footnote_C_3" id="Footnote_C_3"></a><a href="#FNanchor_C_3"><span class="label">[C]</span></a> <a href="#Note_B">See Notes B, C, D, E.</a></p></div> + +<div class="footnote"><p class="noin"><a name="Footnote_D_4" id="Footnote_D_4"></a><a href="#FNanchor_D_4"><span class="label">[D]</span></a> <a href="#Note_F">See Note F.</a></p></div> + +<div class="footnote"><p class="noin"><a name="Footnote_E_5" id="Footnote_E_5"></a><a href="#FNanchor_E_5"><span class="label">[E]</span></a> On the 15th of September, the thermometer stood at 80° +Fahrenheit.</p></div> + +<div class="footnote"><p class="noin"><a name="Footnote_F_6" id="Footnote_F_6"></a><a href="#FNanchor_F_6"><span class="label">[F]</span></a> <a href="#Note_G">See Notes G, J.</a></p></div> + +<div class="footnote"><p class="noin"><a name="Footnote_G_7" id="Footnote_G_7"></a><a href="#FNanchor_G_7"><span class="label">[G]</span></a> <a href="#Note_K">See Notes K, L.</a></p></div> + +<div class="footnote"><p class="noin"><a name="Footnote_H_8" id="Footnote_H_8"></a><a href="#FNanchor_H_8"><span class="label">[H]</span></a> <a href="#Note_M">See Note M.</a></p></div> + +<div class="footnote"><p class="noin"><a name="Footnote_I_9" id="Footnote_I_9"></a><a href="#FNanchor_I_9"><span class="label">[I]</span></a> <a href="#Note_N">See Note N.</a></p></div> + +<div class="footnote"><p class="noin"><a name="Footnote_J_10" id="Footnote_J_10"></a><a href="#FNanchor_J_10"><span class="label">[J]</span></a> <a href="#Note_O">See Notes O, P.</a></p></div> + +<div class="footnote"><p class="noin"><a name="Footnote_K_11" id="Footnote_K_11"></a><a href="#FNanchor_K_11"><span class="label">[K]</span></a> <a href="#Note_R">See Notes R, S, T.</a></p></div> + +<div class="footnote"><p class="noin"><a name="Footnote_L_12" id="Footnote_L_12"></a><a href="#FNanchor_L_12"><span class="label">[L]</span></a> <a href="#Note_V">See Note V.</a></p></div> + +<div class="footnote"><p class="noin"><a name="Footnote_M_13" id="Footnote_M_13"></a><a href="#FNanchor_M_13"><span class="label">[M]</span></a> <a href="#Note_Y">See Note Y.</a></p></div> + +<div class="footnote"><p class="noin"><a name="Footnote_N_14" id="Footnote_N_14"></a><a href="#FNanchor_N_14"><span class="label">[N]</span></a> <a href="#Note_Z">See Note Z.</a></p></div> +<br /> +<br /> +<br /><span class='pagenum'><a name="Page_140" id="Page_140">[Pg 140]</a></span> +<br /> + +<hr /> +<br /> +<h2>CHAPTER III.</h2> + +<p class="cen"><i>Description of the Contagious Typhus of the Ox; its Symptoms, Course, +Progress, &c.</i></p> +<br /> + +<p>I have already written the history of the typhus which affects the ox; I +have shown and dwelt upon the signs and characters of typhus diseases +generally, deducing therefrom the denomination and definition of that of +the ox in particular; finally, I have described the causes which +generate and diffuse it abroad.</p> + +<p>Now, I must make known the various phases and alterations to which the +disease is liable, and which, in the language of the medical schools, +are called its symptoms and characteristics; its progress or course; its +prognosis; its <i>post-mortem</i> appearances, &c. &c.</p> + +<p>This examination, like those which have preceded it, will afford new +foundations for medical practice.</p> +<br /> + +<p class="cen"><span class='pagenum'><a name="Page_141" id="Page_141">[Pg 141]</a></span>I.</p> + +<p><i>Symptomatic Characteristics.</i>—The typhus of the ox, like all +infectious and contagious diseases, offers to observation four +successive changes: 1st, a <i>period of Incubation</i>, during which the +original structure is subject to internal and latent derangements; 2nd, +a <i>period of Initiation</i>, during which the first evident signs of the +disease are manifested; 3rd, a <i>period of Endurance</i>, during which the +phenomena are fully developed; 4th, a <i>period of Decline</i>, or wasting +atony.</p> + +<p>These divisions and classifications, it will readily be conceived, are +rather fanciful, for nature does not adapt herself to our methodical +forms. Still we shall abide by them, because they have their relative +and practical utility, and because they will afford to the practitioner +suggestions more easily understood; and finally, because the organic +changes are different at these various periods, which in their entirety +constitute the typhus of the bovine species.</p> + +<p>The description of those different phases through which the organism of +cattle smitten with the contagion has to pass, has moreover <span class='pagenum'><a name="Page_142" id="Page_142">[Pg 142]</a></span>been given +in a masterly manner by the veterinary physicians of the different +European countries, especially by those in which opportunities to +observe it have been most frequent—that is to say, by the Russian, +German, and French veterinary doctors, Jessen, Röll, D'Arboval, Gellé.</p> + +<p>The English physicians of the 18th century, as we have already seen, +were also in no respect inferior to those of our own time. Finally, Mr. +Simonds, who published a very able Report on his return from his +scientific exploration in Galicia, in 1857, and the skilful Professor +Bouley, in his recent communications to the Académie de Médecine, in +Paris, respecting his examination of the present cattle typhus in +England, have described the disease with minute exactness, as we +ourselves have verified on the various sick beasts which we have seen +during the last two months.</p> + +<p>1. <i>Period of Incubation.</i>—Several careful experiments, which have been +cited in the historical division of this work, and numerous fortuitous +occasions, have authorized us to assign a duration of nine or twelve +days to the period of incubation, according to the <span class='pagenum'><a name="Page_143" id="Page_143">[Pg 143]</a></span>general conditions +of the epizootia, the manner in which the contagion is transmitted, and +the former state of health of the affected cattle.</p> + +<p>Thus an epizootia at the outset, either when it has become general, or +when it is at its decline, does not always transmit typhic miasma of the +same virulent intensity, nor does it always provoke in the frame a +labour of incubation which is invariable. The contagion transmitted from +animal to animal living continually in the same stalls or sheds is +followed by an incubation more quick and active than that which results +from a chance contact in the markets, or from a contagion produced at a +distance, by the transmission of the miasmatic effluvium along the +public highways.</p> + +<p>Let us add to these considerations the relative state of each animal's +health, and we shall then perfectly understand that the incubation must +vary both in its continuance and in the characteristics of its +manifestation. In some animals it scarcely betrays the derangements +produced by its morbid operation: they preserve their appetite and their +usual looks. A close and attentive observation would alone be <span class='pagenum'><a name="Page_144" id="Page_144">[Pg 144]</a></span>able to +distinguish some slight alterations in their way of living, in the +regularity of their rumination and sleep. But in others, there is no +mistaking a something irregular and unusual in their appearance and +living; the vital state is no longer the same. Thus an animal which used +to be cheerful and familiar becomes silent and solitary; it browses the +grass with less eagerness and avidity; it lies down more frequently and +longer; it lingers by the side of the hedge along the field, or it +wanders about, here and there, with a listless look, and without any +object. Others moan and complain, bellowing at intervals in an unusual +manner, very expressive of languor and pain.</p> + +<p>But apart from seasons of epizootia, the beasts too often exhibit these +imperceptible shades of variety in their looks and actions for the +attention to be struck by them; these changes, therefore, are almost +always unnoticed.</p> + +<p>However, the typhic miasma absorbed at the same time by the respiratory +and digestive mucous membranes serves to modify the qualities of the +blood, and secretly reacts on the <span class='pagenum'><a name="Page_145" id="Page_145">[Pg 145]</a></span>nervous system; soon after, the +animal exhibits more decidedly those changes which previously were +hardly to be detected; his want of appetite is more marked, his sadness +more obvious, and his attention fixes itself more slowly and carelessly +on the objects which surround him. When he is in the shed, his usual +food is found in excess of his wants, his thirst is much keener and more +frequent, and a continual dejection and lowness of spirits or a +transitory agitation disturb all his functions. When the farmers or +graziers notice these premonitory signs for the first time they pay but +little attention thereto; but if the contagion has found its way into +their stalls and sheds they are no longer deceived by them, but begin to +apprehend that in a day or two fresh victims will be added to the +number.</p> + +<p>2. <i>Period of Initiation.</i>—Soon the elaboration of the virulent miasma +in the organic structure changes the quality of the blood and humours, +the functions of assimilation and secretion are modified, the nervous +centres receive vitiated organic elements and are disturbed in their +physiological conditions, and the smitten animal displays that state of +latent uneasiness <span class='pagenum'><a name="Page_146" id="Page_146">[Pg 146]</a></span>which he is imperfectly conscious of by a general +look of heaviness and stupor (<span class="Greek" title="pneuma">Τυφος</span>), which has suggested for +this disease its name of typhus.</p> + +<p>Indeed, the poor animal's eyes are fixed, the hearing becomes obtuse or +indifferent, as may be seen in the sinking of the ears, those organs +which are so sensitive, so contractile, and so vigilant in herbivorous +animals. With the head hanging down and motionless, the neck stretched +out, their forelegs open and spread, their buttocks drawn together and +one of them completely lax, they seem to succumb beneath the weight of +their bodies. In a word, the animal exhibits through its whole bearing a +heavy sadness, a general dejection, which bespeak a great derangement in +the whole structure. From this time, in the animals which are most +seriously affected, the appetite ceases, the rumination becomes +irregular and partial, whilst in some others the appetite and rumination +are maintained in different degrees.</p> + +<p>But the incubation of the morbid elements pursues its course, the +alteration of the blood becomes general, and the circulation is +increased and quickened. After this the fever <span class='pagenum'><a name="Page_147" id="Page_147">[Pg 147]</a></span>interposes and stops the +secretions, that of the udders is dried up, the mucous channels cease to +flow, the mucous membrane of the mouth becomes whitish, the little +glands situated on it are more permanent, especially in the +circumference of the gums; the floor of the tongue and the larynx are +inflamed, the mucous membrane of the cow's sexual organs is red and +furrowed with livid streaks, the white of the eye is parched, and the +skin feels alternately hot and cold, as well as the horns and hoofs.</p> + +<p>Some of the sufferers have an external horripilation, transient +shiverings are felt in the front and hind quarters and at the junction +of the limbs with the trunk. Some pregnant cows near their delivery +miscarry. In a word, at this period of irritation, the whole frame is at +war with the typhic elements which besiege it, and which overcome the +preservative power of the vital forces, and from this general +disturbance arises an incandescent fever, which drains and stops all the +secretions at their source.</p> + +<p>These general symptoms are the first signs and warnings of functional +derangements more significant, which may, however, vary according to the +predispositions of each animal, <span class='pagenum'><a name="Page_148" id="Page_148">[Pg 148]</a></span>and transfer their evolutions either to +the nervous centres or to the respiratory mucous membrane, or to that of +the digestive channels, in the inflammatory and febrile form of the +contagious typhus. Such at least is what we observe in the typhus of +1865 in England.</p> + +<p>The functional derangements, in truth, subordinate to and depending on +the predispositions exhibited by the cattle, are far from being the same +in all. In some, the nervous derangements predominate; in others, it is +those of the respiratory, and in others, it is those of the digestive +channels.</p> + +<p>As in this period of irritation the nervous centres are more +particularly affected, the animal suffers cerebral and rickety pains, a +constant cephalalgia, which provokes vague anxiety; he is sometimes +cheerful, sometimes wild and furious; he clenches his teeth and yawns, +the muscles of his face spasmodically contract, the spine feels very +sensitive when pressed, a burning and insatiable thirst comes on, the +breathing is hurried, and the intestinal evacuations are suspended.</p> + +<p>In this form the toxæmia appears to <span class='pagenum'><a name="Page_149" id="Page_149">[Pg 149]</a></span>concentrate about the nervous +centres—as is observed elsewhere at the outset of certain violent +fevers, in the typhus and typhoid fever of man, for instance—and some +of their number may perish the victims of these nervous disorders, and +even fall as if struck with electricity. They die apparently from the +result of the typhic poison; for at this second period, we do not trace +in the nervous centres those injuries which might account for so sudden +a death.</p> + +<p>When the respiratory apparatus concentrates upon it the febrile +congestion, the breathing becomes painful, accelerated, embarrassed, +sometimes convulsive, and a deep, oppressive cough is heard from time to +time. The animal, under the yoke of this oppressive uneasiness, turns +his head from right to left, scents, and seems to question his flanks, +where the seat of the disorder is; and then, whether the pulmonary +affection is congestive or inflammatory or emphysematous, he may die of +the consequences of obstruction to the pulmonary circulation and from +the alteration of the blood, under the influence of a <span class='pagenum'><a name="Page_150" id="Page_150">[Pg 150]</a></span>slow asphyxia, +but only at the third or fourth period.</p> + +<p>Finally, when the typhus localizes more particularly its morbid +phenomena on the digestive channels, we discern local alterations on the +floor of the tongue and the buccal mucous membrane, spots of livid red, +leaving behind them ulcerations of greater or less extent and depth on +different parts of the intestinal canal. In this form, which follows +more regularly all the periods, constipation is obstinate at the outset, +evacuation of the bowels takes place with difficulty, the fæces are hard +and the urine scanty, the belly is inflated and sensitive.</p> + +<p>Sometimes at this period of initiation, one of these three symptomatic +forms—the nervous, the pulmonary, and the digestive—may predominate +exclusively, so far as to mask the disease as a whole, and to constitute +it a special malady. But in that case, it is only the exaggeration of +the functional derangements which in their total constitute the typhus: +for when the distemper pursues its course, these three principal centres +of life <span class='pagenum'><a name="Page_151" id="Page_151">[Pg 151]</a></span>are always affected in different degrees. Thus, not one of the +cattle smitten with the typhus goes through all the phases of the +disease, without suffering at a given moment in its nervous, +respiratory, and digestive functions.</p> + +<p>In this respect, the typhus of the ox presents an apparent analogy with +the typhoid fever in man, although it is different. Consequently, the +name of <i>typhus fever</i> given by some veterinary surgeons, is not +altogether inapplicable to it.</p> + +<p>3. <i>Period of Duration.</i>—At this stage of the disease, which may be +said to extend from the fourth to the seventh day, the nervous +derangements are confined to symptoms of uneasiness and sensibility +along the dorsal spine; for those cases which exhibited more violent +derangement in the nervous functions have proved fatal. In this period +of the disease the breathing is more embarrassed, particularly when the +pulmonary form of the disease prevails. The pulse, which is hard and +frequent, indicates from forty to sixty pulsations; the beatings of the +heart are more violent and audible; the mucous membranes, dry at the +<span class='pagenum'><a name="Page_152" id="Page_152">[Pg 152]</a></span>outbreak, recover their secretions, but these latter are endowed with +irritating properties. Thus the eyelids, swollen and tumefied at the +edges beneath the lashes, drip with a corrosive liquid, which soon marks +its furrow along the chanfrin; the bronchiæ, the trachea, the nostrils, +the salivary glands, exude a serosity which runs out of the nasal and +buccal orifices. The exanthematic eruption having discharged itself +through the digestive channels, constipation is followed by diarrhœa, +rumination is completely stopped, the beast declines all solid +nutriment, and pants for drinks,—for those especially which have a +slight taste of acidity in them.</p> + +<p>The derangements at this period pursue a rapid course—the breathing +becomes more and more difficult, the skin is hot and dry, the hairs +stiffen more and more, gases are developed in the cellular tissues +beneath the skin, along the dorsal vertebræ, at the abdominal folds of +the posterior limbs and under the abdomen, in the form of flat, uneven, +crepitant tumours, which crackle when pressed with the hand; the +diarrhœa becomes more liquefied <span class='pagenum'><a name="Page_153" id="Page_153">[Pg 153]</a></span>and irritant, for then it is no +longer a flow of droppings covered with mucus which is expelled, but +secretions already putrid, sometimes reddish in colour, and attended +with fœtid gases, which induce tenesmus in the rectum, and force up +the tail. The animal grows perceptibly lean, his dejection is extreme, +and cows which are with calf miscarry.</p> + +<p>At night, the animal seems to have an increase of fever, sometimes of a +remittent type, after which he becomes drowsy and lies down to rest +himself or to sleep, if he can; but the difficulty of breathing, the +abdominal pains, soon force him to rise again, which he cannot do +without an effort.</p> + +<p>4. <i>Period of Decline and Sinking.</i>—This stage is observed to extend +from the eighth day to the twelfth or the fourteenth. The morbid +functions pursue their course, for the disease has its regular phases +and a successive variation of phenomena. The secretions, which a few +days before were fluid and irritating, have undergone a change; they +have become thick and purulent, they flow more slowly <span class='pagenum'><a name="Page_154" id="Page_154">[Pg 154]</a></span>from the ocular +mucous membranes, and also from the nasal and buccal, which are red and +inflamed, and they already emit a fœtid smell. The dull tarnished +eyes become hollowed, purulent mucus lodges within their orbits, the +bronchiæ are stopped up, the breathing grows louder and more panting, +the animal instinctively stretches his neck to ease it; the wasting of +the flesh exposes the bones of the sacrum and coccyx, laying bare the +vertebræ and the ribs; the emphysematous tumours are more extensive and +crackling; the skin, less heated, wrinkles up and splits about the bony +protuberances; the udders are crusty and excoriated; detached boils, +hard and rounded at first, then soft and purulent, begin to show +themselves on the trunk and the upper parts of the limbs. The +diarrhœa, still frequent, becomes bloody and intolerably offensive.</p> + +<p>At this final period the organic structure yields to the effects of a +general alteration of the liquids and solids. The vital force has lost +the power of reaction; a mass of blood, decomposed by the double +influence of a <span class='pagenum'><a name="Page_155" id="Page_155">[Pg 155]</a></span>virulent toxæmia and the obstructions of respiration, +conveys to all the organs a principle of dissolution; the nervous system +is in a manner paralysed, as is shown in the animal's insensibility.</p> + +<p>The secretions stop up the various channels and cavities; they lodge +within them; they undergo a putrid decomposition, and pass out with +difficulty in the form of a purulent and bloody flux, in the highest +degree infectious. Very soon the sick animal has ceased really to live; +it struggles and labours with its agony; if the lungs are clogged with +gas or fluid they rattle hurriedly and often; the animal cannot hold its +head up even when lying down, and when standing moves it to and fro as +if affected with the natural shaking of old age, and as if seeking to +ward off some indescribable evil, the occurrence of which it was +awaiting.</p> + +<p>The animal's body is a prey given up beforehand to the laws of organic +decomposition: the internal mucous membrane of the cheeks and lips peels +off in strips when rubbed; the sores on the skin have a livid and +gangrenous look; the eggs which the flies deposit on the <span class='pagenum'><a name="Page_156" id="Page_156">[Pg 156]</a></span>edge of the +eyelids and at the nasal orifices, or on the excoriations of the skin, +quickly pass into the state of larvæ. The air they expire is cold and +infectious; the native caloric, extinguished in every focus +successively, disappears; the vaginal mucous membrane is tumefied, the +anal opening gapes, and from it flows a bloody and decomposed liquid +which the rectum can no longer expel. The mouth, half open and coated +with a thick glutinous foam, vainly tries to inhale long draughts of air +which can no longer reach the lungs. Finally, if the animal is lying +down, he expires in slow agony, his head borne down by its own weight; +or, if standing, he sinks and falls down, his death having anticipated +the fall.</p> + +<p>Such are the symptoms—the subjective signs which enable us to detect +the contagious typhus of the ox. But all animals do not exhibit these +disorders of the vital functions with the same regularity and excess. +Some of these we have seen, from first to last, sustain the internal +effects of the morbid process—in some sort passively—without revealing +any deep derangements in the nervous, respiratory, and digestive +functions. The <span class='pagenum'><a name="Page_157" id="Page_157">[Pg 157]</a></span>poisonous virus had smitten them; they suffered in their +general structure; they looked stupefied; they lost, at a given moment, +their appetite and rumination; they had fever; their breathing had +become short and frequent; they had diarrhœa; they gradually lost +flesh, and the excreta passed through certain changes and +transformations. In a word, the animal had manifestly the bovine typhus; +but, thanks to a relative immunity, to a special organization, which +renders some of these beasts capable of resisting the contagion for a +long period, and sometimes altogether<a name="FNanchor_O_15" id="FNanchor_O_15"></a><a href="#Footnote_O_15" class="fnanchor">[O]</a>—thanks to that variety which +we observe in different constitutions (for small-pox and typhus in man, +and the true typhoid fever in animals, do not operate with the same +violence on all alike)—thanks to this privileged organization,—we have +seen some oxen pass through every stage of the disease without +exhibiting this terrible train of morbid phenomena.</p> + +<p>In these cases—for even this mild form of <span class='pagenum'><a name="Page_158" id="Page_158">[Pg 158]</a></span>the distemper at last +produces death—the injuries fix themselves more exclusively on the +digestive channels, and we witness, in dissection, ulcerations in some, +in others mere spots of a livid red, more or less extensive.</p> + +<p>Finally, although the typhus be one of the gravest maladies which +destroy and decimate cattle, all sick animals are not mortally affected +thereby. In the present epizootia, five per cent., as nearly as can be +ascertained, recover; and when that happens, signs of a favourable omen +are observable during the course of the attack. In these favourable +instances, indeed, the symptoms, even though they exhibit a certain +gravity, pursue a regular course; fever does not become remittent; the +fæcal discharge is copious and easy, with less fœtor; the animal +loses flesh slowly and progressively; the tumours are cutaneous, +inflammatory; their character is good, depurative, and rather purulent +than gaseous and crackling. The droppings do not show that high degree +of pestilential decomposition described above; the animal in his drink +welcomes and digests a mixture of bran and flour; the secretions of +purulent mucus and the fæcal discharges dry <span class='pagenum'><a name="Page_159" id="Page_159">[Pg 159]</a></span>up and stop in the early +part of the period of decline; the epidermis of the openings through +which they passed out peels off in thin scales, and afterwards in scurfs +or husks—in a word, the economy does not experience those acute +disturbances which strike one of the tripods of life—that is to say, +either the nervous centres, the lungs, or the digestive organs.</p> + +<p>Now, in these curable cases, in which the cure is most generally due to +nature's own efforts, but which a systematic treatment might render far +more frequent, the convalescence is long, and requires great attention +and a well-regulated diet, in which the food is carefully measured and +divided. Here there must be a rigid superintendence. A laxity in the +watchfulness, or too much reliance on the reviving health, have produced +sudden relapses, and been fatal to many sick cattle, which had been +looked upon as thoroughly cured. For it may well be conceived that +convalescent animals, after sustaining such violent derangements in +their health, and having been brought down to the lowest degree of +prostration and marasmus—to a reconstitution, we may call it, of the +solids and <span class='pagenum'><a name="Page_160" id="Page_160">[Pg 160]</a></span>liquids—have a devouring hunger. If, therefore, the keeper +who looks after them unhappily forgets that the principal lesions or +sores are seated in the stomach and intestines, and if he gives them too +much solid nutriment, he impedes the cure, irritates the ulcerations not +yet thoroughly covered over, and soon adds another victim to those which +had already died.</p> + +<p>This convalescence lasts from fifteen to twenty days, and the animal +only recovers its health at last by slow degrees. Still the careful +keeper need not be afraid of a relapse when he is patient and watchful.</p> + +<p>Such, then, is the contagious typhus of the ox. Type of the unreturnable +infectious diseases, its virulent miasms undergo within the structure a +series of transformations: they produce in the frame a general disorder +fully capable of annihilating the predisposition or aptitude of the +animal to receive the taint. A disease essentially specific, it affects +the principal centres of life; it kills its victim both by its deadly +virus and by the local derangements to which it gives rise; for how is +it possible to preserve life when the whole nervous <span class='pagenum'><a name="Page_161" id="Page_161">[Pg 161]</a></span>system, that +promoter and regulator of all the functions, is upset?—when the lungs +which revivify the blood, when the digestive organs which are the very +sources of alimentation, are smitten with stagnation?—when, in fine, +not only these vital centres have ceased to operate, but when each by +itself is the cause of torturing pains and exhaustion?</p> + +<p>The typhus, moreover, is observed in all animals of the bovine species, +whatever may be their race, their age, or their sex. The recovered +animals may live with impunity amidst diseased herds of cattle, thanks +to its non-relapsive nature. Jessen has even witnessed cows which, after +their own cure, communicated a sort of immunity to their offspring. For +the same reason it is that epizootias are less fatal in those countries +where they often occur, the constitutions of those animals which are +engendered amongst such habituated herds, preserving a prophylaxy +inherent to the blood which has been transmitted to them.</p> + +<p>Besides, what a pregnant subject is this for the physician, and what +more meritorious task can he set himself than the treatment of <span class='pagenum'><a name="Page_162" id="Page_162">[Pg 162]</a></span>such a +distemper, which reason assures him must eventually lead to the cure and +eradication of the same complaint in the human species?</p> + +<p>From a cause which as yet has been indistinguishable and imponderable, +what important, what marvellous results loom in the future! The air +seems to us pure and wholesome, yet it conceals a typhic miasma of the +most deadly kind; it carries this pernicious principle into the richest +meadows, where we see feeding flocks and herds which to us seem +exuberant with health. Then this miasma is inhaled and absorbed, and it +meets in the frame the special and indispensable organic element which +is needed for its multiplication; there it undergoes certain latent +transformations, and a fermentation, a germination, which we call +<i>incubation</i>, in order to explain a process which we cannot understand. +Then fever is kindled, all the functions are disturbed, and the sick +animal is struck down, leaving us wondering, ignorant, and powerless +spectators in the presence of phenomena which, nevertheless, are the +eternal work of nature and have endured through all time.—But if <span class='pagenum'><a name="Page_163" id="Page_163">[Pg 163]</a></span>in +the invisible typhic atom nature gives us death, it also gives us life +in the zoosperma.</p> +<br /> + +<p class="cen">II.</p> + +<p class="cen"><i>Lesions found in the Bodies of Oxen after Death.</i></p> + +<p>The description which we have given of the disorders produced in the +different functions by the operation of the typhus, may easily suggest +what must be the lesions exhibited by the organs of the body.</p> + +<p>Death, we have said already, may overtake the disease at any of its +periods, and thus show every aspect and every degree of the organic +lesions. Such an animal being struck down at the period of initiation, +will not, of course, present the changes and varieties of the period of +decline, and <i>vice versâ</i>.</p> + +<p>In general, the state of the dead bodies is that of the most decided +marasmus; the remains are intensely repulsive, as well by the stench +they emit as by the sight they afford; and, in summer especially, +decomposition sets in with great rapidity. Consequently, the utmost care +is required in conveying <span class='pagenum'><a name="Page_164" id="Page_164">[Pg 164]</a></span>them from place to place; and this attention +is the more essential, because in the transit, the cavities being +deprived of their contractile power, let flow the pestilential liquids +which they contain, thereby infecting the carriages and public roads. +The urgent necessity there is to inhume at once these dead bodies, the +most active agents in diffusing the contagion, is equally the drift of +this observation.</p> + +<p>The deceased animal, as a subject of anatomy, enables us to certify the +seat of the emphysematous tumours, and to see that they are really due +to the air which insinuates itself into the cellular tissue, and which, +receding from the pressure of the fingers between the cells, produced +the crackling sound we noticed above. This penetration of the air is, +moreover, a far more general effect than was supposed.</p> + +<p>It is ascertained, likewise, from the examination of these subjects, +that the round, fluctuating, and smaller tumours, are indeed purulent +gatherings, which occasionally find a passage into the layers and +interstices of the muscles.</p> + +<p>The muscular flesh is usually flabby, <span class='pagenum'><a name="Page_165" id="Page_165">[Pg 165]</a></span>bloodless, unsightly, of a very +nauseous smell; and it would be difficult to imagine that the most +avaricious trickster would dare to offer even the most presentable parts +of it for sale and consumption. But when the expedients and artifices +known to the butcher's trade are had resort to, when, regardless of the +public health, the unprincipled dealer selects the most fleshy parts, +when he dresses and adorns them by colouring them over with the blood of +a healthy beast, the unwary eye of the purchaser may be deceived. +Observe, that we are now speaking of cattle that have died in the last +stage of this marasmus, so that we might suppose, even if the many +summonses before the magistrates, and the too moderate fines which have +been imposed on the guilty parties, had not shed the broadest light upon +the fact, that <i>a large number of sick cattle which had been slaughtered +at different stages of this frightful disease, have been dressed and +adorned, exposed for sale, sold, and eaten by a very large portion of +the inhabitants of London and of the country likewise</i>.</p> + +<p><i>Digestive Channels.</i>—The mucous membrane of the buccal cavity is, for +the most part, of a <span class='pagenum'><a name="Page_166" id="Page_166">[Pg 166]</a></span>livid whiteness; ecchymosed stains, and sometimes +ulcerations, differing in their form and number, are visible on the +floor of the tongue. Mr. Simonds has had an anatomical model +constructed, which presents a perfect type of these ulcerations, some of +which are of a scarlet hue, with perpendicular edges. The <i>stomachs</i> +exhibit a variety of ulcerations.</p> + +<p>The <i>paunch</i>, or first stomach, always contains a large quantity of food +intended for rumination; sometimes these aliments are dry, and lie +sticking to its sides; at other times they are diluted with water which +had not yet been absorbed after drinking. The inner membrane of this +first reservoir may show flat spots, with livid injections of different +sizes.</p> + +<p>The <i>honeycomb</i>, or second stomach, generally exhibits the same injuries +as the paunch.</p> + +<p>The <i>manyplies</i>, or third stomach, contains between its laminæ hard, +pulverulent, and dry alimentary substances, which are seen sticking to +the different leaves. On removing these substances, some ecchymosed +spots are laid bare, the epithelium of which easily peels off; +<span class='pagenum'><a name="Page_167" id="Page_167">[Pg 167]</a></span>sometimes ulcerations, and even perforations, are visible.</p> + +<p>The <i>reed</i>, or fourth stomach, whose sides are thicker, more fleshy, and +more vascular, exhibits within its folds various kinds of lesions or +sores: they consist of large flat stains of a darkish red, more or less +soft, and sometimes ulcerations red on their deep surface, with clean +edges.</p> + +<p>As for the intestines, properly so called, the <i>duodenum</i> shows the same +injuries, but most generally large ecchymosed spots.</p> + +<p>The <i>small intestine</i> appears on the outside, even when it preserves its +place in the abdomen, of a reddish colour, lined with vessels distended +with blood, the signs of a general congestion of its membranes. The +examination of the mucous membrane, after it has been cut open +lengthways, shows, indeed, that this portion of the digestive tube is +the principal seat of the distemper; for, independently of this general +injection, you perceive ulcerations which have succeeded to detached +pustules or lengthy flat spots, the result of a cluster of several of +Peyer's glands, brought together by the plastic influence of +<span class='pagenum'><a name="Page_168" id="Page_168">[Pg 168]</a></span>inflammation. These flat spots, or wafers, very similar to those we +observe in the typhoid fever of man, are inflamed and ulcerated in +different degrees.</p> + +<p>The mucous membrane of the <i>large intestine</i> exhibits lesions depending +on the period of the disease. About the third period, the injection is +sometimes general, especially near the rectum; but in the fourth and +last period we often meet with ulcerations which are smaller in the +upper part, larger and deeper about the lower or rectal part. The +membrane of the sexual parts of the cow is strongly injected, and of a +dull red colour.</p> + +<p>As we have seen, the different organs of the digestive apparatus may, in +this typhus, offer to view extensive alterations perfectly consistent +with the gravity of the symptoms or the functional derangements. In two +cases in which disorders of the respiration had prevailed, and which had +been sacrificed on the eighth or tenth day of the disease, we only +observed partial injections of a very limited character, either on the +gastric membranes or on that of the intestine, and which <span class='pagenum'><a name="Page_169" id="Page_169">[Pg 169]</a></span>might have +been detected in the case of common intestinal inflammation. Therefore, +in these two cases, the characteristic lesions of the typhus, if they +must be localized in the intestine, were, so to speak, absolutely +wanting. It was, we will not say exactly the same, on four other +animals, three oxen and one cow; but if, in two of them, the fourth +stomach was inflamed, if in the third the small intestine was congested, +and if, lastly, in the cow the large intestine showed ulcerations, we +could not in these lesions distinguish those of typhoid fever.</p> + +<p>These facts struck us with great surprise, for we were far from +suspecting them. We hoped, on opening the intestine of these animals, +which had certainly all died of the typhus, to meet assuredly in a +determined spot some well-known lesion declared beforehand. To our great +astonishment, such has not always been the case. So that our theories, +conclusive as they seemed on the identity of the ox typhus and the +typhoid fever in man, and which more than anyone else we wished to see +confirmed, must submit to observation.</p> + +<p>In fine, in this epizootia the intestinal lesions <span class='pagenum'><a name="Page_170" id="Page_170">[Pg 170]</a></span>or sores present +different appearances. Developed to the utmost in some cases, so much so +as to exhibit ulcerations at the root of the tongue as well as in the +intestines, and to be in a manner the excess of the injuries which are +seen in typhoid fever, they are in other cases scarcely perceptible, and +sometimes entirely absent, when the animal is struck down in the third +or fourth period, that is to say, when the exanthematic or pustular +state has had time to develope itself on the digestive channels. One of +these animals seized by Mr. Tegg at the Camden Town market, was in such +a state of exhaustion that he could not be driven to the +slaughter-house, only two hundred yards distant; they were forced to +fell him on the spot midway, in order to have him conveyed to the place +of dissection. We only detected partial injections on the digestive tube +of this beast. The pulmonary emphysema which had caused this animal's +death was developed in the highest degree.—He was opened at the request +of M. Bouley, of Alfort.</p> + +<p><i>Apparatus of Respiration.</i>—Here, again, the <span class='pagenum'><a name="Page_171" id="Page_171">[Pg 171]</a></span>typhus shows us injuries +which differ from those of typhoid fever; for if the breathing is always +more or less obstructed at the outbreak of this fever, no serious +organic change in the lungs is the consequence thereof. In the ox +typhus, on the contrary, when the pulmonary form prevails, the +derangements of the respiratory organs are remarkable. Thus, the mucous +membrane of the nostrils, from which flows a purulent and fetid mucus, +is sometimes ulcerated and excoriated. The larynx and the trachea or +windpipe, choked up with frothy mucus, show the same alterations, though +less frequently. The lungs, which are rather congested than inflamed, +are emphysematous, the air having entered and distended the cellular +tissue which unites the lobes together.</p> + +<p>In some cases, the lungs are so gorged with air that their lobes +constitute but a single heap, rendering them irrecognisable, so greatly +do their volume, their specific gravity, and their spongy aeriform +aspect differ from the natural state.</p> + +<p><i>Apparatus of Circulation.</i>—The inner sides <span class='pagenum'><a name="Page_172" id="Page_172">[Pg 172]</a></span>of the heart show +ecchymosed spots, and the same is the case with the larger vessels. The +blood, diminished in its quantity and altered in its quality, is +blackish and more fluid; but in most cases it coagulates instantaneously +and in a mass, without separating into its solid and liquid parts.</p> + +<p><i>Nervous System.</i>—Having observed and dissected the dead bodies at the +slaughter-houses of the markets, we were not able to examine either the +brain or the spinal marrow. Besides, let us remark in this place, that +the mode of felling cattle in England would have rendered impossible +such an examination. For the animals are struck with a club, which kills +them both by cerebral concussion and by the direct alteration of the +brain; the instrument having a sharp end which perforates the skull and +injures the cerebral lobes. Nor is this all; the moment the animal is +struck down, a flexible rod is inserted into the hole made in the skull, +and driven as far as the spinal canal, so as to tear to pieces the +protuberance and the bulb, that is to say, the vital knot. This manner +of killing cattle seems to us, <span class='pagenum'><a name="Page_173" id="Page_173">[Pg 173]</a></span>however, preferable to the one adopted +in France, where the animal does not sink till he has been struck +repeatedly with the club.</p> + +<p>But be that as it may, those authors who have examined the nervous +centres of horned cattle which had perished victims of the typhus, have +usually found the meninges, or membranes that envelope the brain, +injected, whilst the brain itself was slightly dotted over with blood.</p> + +<p>These anatomical lesions of the nervous centres being insufficient of +themselves to explain the death at the second period, we have +endeavoured to give the explanation of it in treating of the symptoms.</p> + +<p>The other organs, the spleen, the liver, the kidneys, present +alterations of a secondary interest only.</p> +<br /> + +<p class="cen">III.</p> + +<div class="blockquot"><p class="hang" style="margin-left: 2em;"><i>Diagnosis—Prognosis—Use of the Flesh of Animals which have +Died of the Typhus—Danger of direct Absorption.</i></p></div> + +<p>The typhus of the ox has such distinct and strongly marked +characteristics that it is not <span class='pagenum'><a name="Page_174" id="Page_174">[Pg 174]</a></span>easily mistaken. However, to conform +ourselves to received custom, I will say some words about the principal +symptoms of some distempers affecting the ox, between which and typhus +unprofessional persons might be embarrassed, and hesitate to distinguish +them. We will transfer, however, those particulars pertaining to the +diagnosis to the part written for the special use of agriculturists, +farmers, and graziers, in order that they may readily find whatever it +may be necessary for them to know when they chance to have any sick and +tainted cattle to treat and cure.</p> + +<p>We have likewise a few words to say on the subject of the prognosis of +the disease, as regards its propagation and its time of lasting. +Finally, we will unfold a question of very real importance in +hygiene—we mean the use and consumption of the flesh of animals as +food, and the danger which may accrue to man and other animals from +contact with their dead bodies, or fragments of the same.</p> + +<p>The diseases of the ox, which we are accustomed to consider as +distinguished from typhus, are the contagious peripneumonia, the +<span class='pagenum'><a name="Page_175" id="Page_175">[Pg 175]</a></span>apthous fever, and the "charbonneux" typhus; but, as we have just said, +we will mention by-and-by their chief characteristics.</p> + +<p>Everyone is anxious, and natural indeed is that anxiety, to know what +this epizootia will become—what will be its course; how long it will +last; whether it will extend its ravages over the whole extent of the +three kingdoms; and if, in fine, it will invade all Europe.</p> + +<p>To answer in a precise manner these questions would be a difficult task; +for who amongst us can assign at present any definite course to the +atmospheric variations? and yet they have a genuine influence on the +progress of the epizootia. On the other hand, the measures which have +been taken hitherto to confine the contagion to its different foci, have +unhappily proved almost ineffectual, but it may be hoped that, assisted +by experience, we shall be able to resist the evil more effectually, and +check its propagation.</p> + +<p>If the atmospheric conditions and the preventive measures could not +modify the spread of the distemper, we should have reason to <span class='pagenum'><a name="Page_176" id="Page_176">[Pg 176]</a></span>dread a +still greater extension of the contagion; for the virulent character of +the epizootia appears to be of an exceptional intensity, and we may +perhaps compare it with the famous epizootia, of the middle of the +eighteenth century, which for ten years afflicted all Europe with its +ravages, striking down six millions of horned cattle.</p> + +<p>Let the reader cast an eye over the extracts borrowed from the +physicians of the principal faculties who have described this typhus, +and which we have reproduced in the first part of this book relating to +its history, and he will then be convinced that the disease is +absolutely the same as that which then raged so fiercely. And if that is +the case, we must anticipate that it will extend its ravages whilst +prolonging its duration. Already it has spread to Holland and Belgium; +Hungary and other provinces in the south-east of Germany—a fact much +less surprising—are likewise smitten with it; and now we hear the news +that France, though so vigilantly on her guard, has seen her frontiers +passed over. In spite of the <i>cordon sanitaire</i> which she had prudently +established <span class='pagenum'><a name="Page_177" id="Page_177">[Pg 177]</a></span>everywhere, some horned cattle have been seized with the +typhus at the town of Raubaix, in the north.</p> + +<p>Without setting ourselves up as pessimists, let us declare that we must +expect that the contagion will continue to spread. Let us make up our +minds to this, in order to take the necessary sanitary measures, and set +ourselves seriously to work by trying the preventive treatment. But, +alas! between the Government, the municipal corporations, the +agricultural societies, the cattle proprietors, and, with regret we add, +the veterinary surgeons, there has been sadly wanting, up to the present +time, that mutual understanding; that prompt and decisive action, and +those pecuniary advances which are so necessary to encounter and contend +with this great calamity.</p> + +<p>As for estimating with any approach to accuracy the sacrifice of +property; the pecuniary loss, which this fatal epizootic may occasion +the country, the want of exact statistics as to the number of cattle +which have already been struck down will not permit us to do it. <span class='pagenum'><a name="Page_178" id="Page_178">[Pg 178]</a></span>But we +may, perhaps, already set it down approximately from 50,000 to 60,000 +head of cattle for England and Scotland, until we have obtained more +precise statistical information on this significant point of inquiry.</p> + +<p>That would represent, however, a very considerable capital; for if we +compute the loss of each animal at the average sum of 15<i>l.</i> only, the +sacrifice already incurred would not be less than from 750,000<i>l.</i> to +900,000<i>l.</i> This sacrifice in money might possibly have proved the be +all and the end all; and at this point we might, perhaps, have arrested +the contagion, had we all been able to act advisedly and harmoniously +together, in the name and for the interest of the public, from the first +appearance of the disease. But this calculation of, let us say, +900,000<i>l.</i>, is made on the supposition that each cattle owner had been +willing to abide by his own loss; whereas, unfortunately, many of them +have striven to shift it on others, and large numbers of the sick and +tainted beasts having been sold and consumed, a proportionate sum thus +recovered by those avaricious men must be of course <i>deducted</i> from this +estimate. Deducted, indeed! Considering the <span class='pagenum'><a name="Page_179" id="Page_179">[Pg 179]</a></span>consequences on the public +health, is it not rather an aggravation than a mitigation of the loss?</p> + +<p>These last assertions naturally lead us to inquire whether we are not +justified in saying that the flesh of sick and tainted cattle, thus +circulated and consumed, has not had its baleful effects on the public +health.</p> + +<p>The butchers who sold the flesh of these sick and tainted cattle have no +doubt been careful to abstain from using it in their own families; and +the first time they speculated on the health of their fellow-citizens, +well knowing what they did, their conscience probably reproached them +with the misdemeanour. But afterwards, when no bad consequences to their +customers had been seen, their own impunity, joined to this apparent +harmlessness to their neighbours, rendered them bolder, and it became a +daily habit with them to sell this peccant offal, which poisons even the +earth by its contact.</p> + +<p>Moreover, the graziers themselves were in league with the butchers, and +took care to slaughter the affected animals before the wasting of their +flesh by the progress of the distemper had bereft them of their greatest +<span class='pagenum'><a name="Page_180" id="Page_180">[Pg 180]</a></span>value. Their private interest prompting them thus to dispose of the +sick animals as fast as they could, the majority of the tainted beasts +were sold and eaten in the second stage or period of the typhus.</p> + +<p>Now, if the flesh of these diseased animals had been eaten raw, +accidents most terrible and appalling would certainly have been the +consequence, although dogs may have fed upon it without injury. But the +cooking of animal flesh at 100 degrees of heat has the property of +destroying for a time the septic germs, as the famous debates now being +held by the experimentalists who are studying the subject of spontaneous +generation tend to show. This poisonous meat, therefore, may at first +have been digested without producing immediate ill effects.</p> + +<p>Our medical practice, however, authorizes us to declare that, after +making every allowance for the influences of this extraordinarily hot +summer, digestive and nervous complaints of the acutest description, and +without any special cause to account for them, have been very numerous +indeed during the last two months, and beyond all proportion greater +than they <span class='pagenum'><a name="Page_181" id="Page_181">[Pg 181]</a></span>usually are in London. And we cannot but feel that, if the +cholera should reach the shores of England at this critical conjuncture, +it will find organisms most ready to receive its virus. Then, indeed, if +the typhic miasma come to mix and blend with the choleraic miasma, all +living beings will have to contend with the most deleterious causes of +alterations in their health, and we may (God send it be otherwise!) +witness one of those measureless calamities which, known in former ages +as the <i>Black Pestilence</i>, decimated cattle and men indiscriminately, +and which, when we read the sorrowful accounts of it in history, make +the flesh creep with affright.</p> + +<p>We sincerely hope that such misfortunes may be spared us. But ought we +to abstain entirely and absolutely from consuming the flesh of cattle +smitten with typhus? It is a delicate question, but still we shall +answer it, making due allowance for every interest concerned.</p> + +<p>We conceive that all animals which are smitten with the early effects of +the disorder, which begin to operate at the opening of its second +period, that is to say, when the first <span class='pagenum'><a name="Page_182" id="Page_182">[Pg 182]</a></span>symptoms are declared, such as +stupor, loss of appetite and shiverings, may be handed over to the +butchers. But this must only be done on the <i>positive understanding and +condition</i> that every animal, sick or not sick, in times of epizootia, +shall pass, either in the farm, the market, or the stable, under the +examination of a competent veterinary inspector, who shall mark the +beast when fit to be sold for consumption. With this precaution, which +at present is put in practice in Belgium, every interest is cared for +and guarded—those of the public health as well as those of the cattle +owners.</p> + +<p>But there is another question of some importance which deserves to fix +our attention for a moment. People sometimes inquire whether the +ox-typhus can be communicated to other animals, and even to man, either +by contact, by direct absorption, or by inhaling the miasma floating in +the atmosphere.</p> + +<p>Experiments of great interest might be made on this subject; but we can +already assert, on the evidence of facts publicly known, that the direct +absorption of putrid matter and purulent secretions, and likewise the +mere <span class='pagenum'><a name="Page_183" id="Page_183">[Pg 183]</a></span>contact with tainted flesh, when the epidermis or scarf-skin is +cracked or peeled off, or when the least open sore exists, may give +access to the disease, and produce death, both in man and other animals. +In these cases, the absorbed virus operates, not as a specific agent, +giving birth to typhus, but as a provocative septic agent, endowed with +infectious properties, which infuse into the economy a germ of virulent +and mortal disease. So long as a sound and intact outer skin stands as a +safeguard between us and absorption, we may fearlessly touch and handle +the tainted flesh of these animals. But the slightest sore or abrasion +is an open door to let in death. A young veterinary surgeon, who had a +slight wound in one of his arms, was carried off within forty-eight +hours, as was proved at a coroner's inquest, after he had dissected an +ox which had died of the typhus.<a name="FNanchor_P_16" id="FNanchor_P_16"></a><a href="#Footnote_P_16" class="fnanchor">[P]</a></p> + +<p><span class='pagenum'><a name="Page_184" id="Page_184">[Pg 184]</a></span>We see by this fatal example that we must be particularly careful not to +touch an ox tainted with typhus when we carry about us <span class='pagenum'><a name="Page_185" id="Page_185">[Pg 185]</a></span>any open sore, +unless we take the utmost precaution in order to guard against all +direct contact or absorption. Man, as we have said <span class='pagenum'><a name="Page_186" id="Page_186">[Pg 186]</a></span>and shown, breathes +with comparative impunity an atmosphere laden with the infectious miasma +of this typhus. But that which <span class='pagenum'><a name="Page_187" id="Page_187">[Pg 187]</a></span>to-day is true may not be true +to-morrow; let us, therefore, be also on our guard against the too +continuous absorption of an atmosphere impregnated with these +deleterious principles.</p> + +<p>As for herbivorous animals in general, a similar organization must, in +their cases, predispose them to receive the contagion. Whenever we visit +the markets, we cannot help fearing to see the ox typhus communicated to +the sheep and pigs which are stationed around them. It is an +unquestionable fact that, in certain epizootias, all animals without +<span class='pagenum'><a name="Page_188" id="Page_188">[Pg 188]</a></span>distinction have been smitten and struck down, and the herbivorous +animals more rapidly than any other. The habit of collecting such vast +numbers of cattle in the same market, and on the same day, though +convenient for business, appears to us injudicious, especially during +the prevalence of this scourge.</p> + +<p>This part of our treatise was in the printer's hands when Mr. Simonds +wrote a letter to the Privy Council which justifies all our +apprehensions. The typhus of the ox has been communicated to a number of +sheep, and we must all expect to see this cruel disease assume much +larger proportions than heretofore, since it has now obtained a second +focus for its maintenance and dissemination.</p> + +<div class="blockquot"><p class="right">"Veterinary Department, 23, New-street,<br /> Spring-gardens, +Sept. 25th.</p> + +<p>"<span class="smcap">Sir</span>,—I beg to report that, acting on the +instructions received from you to investigate without loss +of time the statement received at your office relative to an +outbreak of the cattle plague in a remote part of the county +of Norfolk, supposed to have arisen from cattle having been +in contact with some diseased sheep, recently brought to the +premises, I have visited the district in question, and +inquired into all the circumstances of the case.</p> + +<p>"It appears that as far back as the 17th of August <span class='pagenum'><a name="Page_189" id="Page_189">[Pg 189]</a></span>Mr. C. +Temple, farmer and merchant, of Blakeney, received on his +farm 120 lambs which he had instructed a dealer to procure +for him for feeding purposes.</p> + +<p>"The lambs were bought at Thetford-fair on the preceding +day, and were immediately sent by rail to Fakenham, from +which place they were driven to Blakeney, a distance of +about ten miles. On their arrival they appeared to be +fatigued to a greater extent than ordinary, which was, +however, attributed to the heat of the weather and the +exertion the animals had undergone.</p> + +<p>"In addition to this, the shepherd observed that several of +them seemed unwell, and he remarked to his master that they +did not appear to be a 'very healthy lot,' and that he +thought it would be better to return them to the dealer. +Within a day or two of this time the symptoms of illness +were more marked in all the original cases, and many more of +the animals had been attacked. On the 24th two of the worst +cases were removed from the field to the farm premises, and +were placed in a shed for treatment, in which afterwards a +cow was put. On the 25th two of the lambs died, and in +consequence of this, and of the large number which were now +affected, the whole were brought, on the morning of the +27th, into the same yard where the shed previously alluded +to was situated. There is also another shed, separated from +this yard only by some old furze faggots, into which the +cows were driven night and morning for being milked. The +lambs remained in the yard till the morning of the 28th, +when having had some medicine administered to them, they +were returned to the fold and never came again near the +cows.</p> + +<p>"While in the yard three died, two on the 27th, and one on +the 28th, and on the following day two others died in the +field. From this time the disease went on, <span class='pagenum'><a name="Page_190" id="Page_190">[Pg 190]</a></span>so that by +Friday last, the 22nd of September, the day of my visit, +forty-six had either died or been killed, and twenty-seven +were in a very precarious condition.</p> + +<p>"On the 7th of September, ten days after the last exposure +to the sheep, a cow gave evidence of being affected with the +cattle plague, this animal being the one which had been put +into the shed occupied by the diseased sheep on the 24th of +August. A second cow was attacked on the 11th of September, +and a third shortly afterwards, which was followed by +others; so that by the 16th all the cows, six in number, a +heifer, and a calf, were all dead.</p> + +<p>"My examination of the lambs showed that they were +unmistakably the subjects of the plague. The symptoms agreed +in almost every particular with those observed in cattle +affected with the malady, and the <i>post-mortem</i> appearances +were also identical.</p> + +<p>"With a view to ascertain the true nature of the changes +produced in the system prior to death, I had four of the +lambs killed, and from these I took some diseased parts and +forwarded them to the Royal Veterinary College without note +or comment. These parts were examined by my colleague, Mr. +Varnell, who at once recognised the special changes of +structure which are caused by the cattle plague.</p> + +<p>"The whole facts of the case leave not the least doubt of +sheep being liable to the disease termed the cattle plague, +and that when affected they can easily communicate the +malady to the ox tribe; and moreover, that when so conveyed +it proves equally as destructive as when propagated from ox +to ox in the ordinary manner.</p> + +<p>"The case is also more important from having occurred in a +place no less than fourteen miles distant from any other +where the cattle plague exists, thus placing beyond a doubt +the fact of the malady being introduced among the cattle by +the sheep alone.</p> + +<p><span class='pagenum'><a name="Page_191" id="Page_191">[Pg 191]</a></span>"I regret to add that this is not a solitary case of sheep +being affected by the cattle plague. I learned that some +sheep were supposed to be similarly affected belonging to +Mr. R. J. H. Harvey, M.P., on his estate at Crown Point, +near Norwich. This place I also visited, and found a large +flock of upwards of 2000 lambs, among which the malady was +prevailing. A large number had been separated from the +diseased, and gave no evidence of the malady. Very many, +however, had died, and the disease was making rapid +progress. I also examined many of the dead, and found the +<i>post-mortem</i> appearances to be identical with those seen in +the other cases spoken of in this report.</p> + +<p>"In this instance the malady was brought into the estate by +the purchase of some cattle, which afterwards died from the +disease, and which were unfortunately pastured with the +sheep at the time the disease manifested itself.</p> + +<p>"The whole matter is one of the greatest importance, and +which I lose no time in submitting to you for the +information of the Lords of the Council.</p> + +<p>"I have the honour to be, Sir, your most obedient servant,</p> + +<p class="right smcap">"Jas. B. Simonds."</p></div> +<br /> + +<p class="cen">IV.</p> + +<p class="cen"><i>General Considerations on the Ox-Typhus, and the +Recapitulation of the Symptoms.</i></p> + +<p>We have seen the causes, the symptoms, and the cadaveric alterations of +the Bovine typhus, and we may therefore apply ourselves <span class='pagenum'><a name="Page_192" id="Page_192">[Pg 192]</a></span>at present to +the consideration of its pathogenia and its nature. Only, the limits of +this book will not admit of a complete discussion of every point of this +important question of pathology; for if we desired to show in what +respect the typhus differs from, and in what respect it resembles, such +and such a morbid entity, febrile, infectious and contagious like it, +such a dissertation would require a whole volume for itself; we are +therefore obliged to keep within certain limits.</p> + +<p>Like every watchful physician who has applied himself to the study of +comparative pathology, we entertained our own preconceived opinions as +to the nature of this <i>Cattle Plague</i>. Arguing <i>à priori</i> from what we +knew, from the laws of the pathogenia of those exanthematic diseases +which we have alluded to in a former chapter; from the identity of +variola in various animals; from the preventive treatment to which this +identity has led; believing that animals and man have each their typhoid +fever, as they have their variola or small-pox; considering with the +Ecole de Tours, typhoid fever as a variola of the intestinal mucous +membrane, and having proposed, <span class='pagenum'><a name="Page_193" id="Page_193">[Pg 193]</a></span>in 1855,<a name="FNanchor_Q_17" id="FNanchor_Q_17"></a><a href="#Footnote_Q_17" class="fnanchor">[Q]</a> to adopt inoculation as a +preventive treatment, drawing an easy comparison between the typhus we +are now observing and the typhoid fever in man; hoping, we may say, +indeed, to find in this typhus the inoculative and preventive virus +which is required for our typhoid fever, all will understand with what +eager and vivid curiosity we have examined the entrails of the victims +struck down by this epizootia. For, if this typhus had been a genuine +typhoid fever, the bovine species which has already provided the +preventive virus for small-pox, would equally have afforded us the +preventive virus for typhoid fever. In this hypothesis, our proposal to +inoculate the typhoid fever, which up to this time has been tried on +horses only, and in experiments badly conducted, by pupils of the +Veterinary School of Lyons, was perhaps on the eve of being realised. +But we regret to <span class='pagenum'><a name="Page_194" id="Page_194">[Pg 194]</a></span>say, we have been forced to submit to evidence, and to +acknowledge that the present infectious typhus is not the one we require +to provide us with the anti-typhoid virus.</p> + +<p>In the same manner as pathologists disagree as to the question, whether +the typhus and typhoid fever in man are one and the same disease, so +should we long debate, without coming to an agreement, as to that which +relates to the typhus and typhoid fever of the ox. We cannot pretend to +produce a reconciliation between these dissentient schools; all we +desire, is to sum up what observation has suggested to us, on account of +the practical and therapeutic interest belonging to the subject.</p> + +<p>For ourselves, the typhus and the typhoid fever of the ox are two +diseases of the same order, but nevertheless distinct; and the reasons +upon which we ground our opinion are suggested to us by the nature of +the intestinal lesions, the symptoms, and causes of these distempers.</p> + +<p>As we have already seen, the contagious typhus of the ox, at least that +of the present <span class='pagenum'><a name="Page_195" id="Page_195">[Pg 195]</a></span>epizootia, is an infectious disease, which varies in the +intensity of the functional disorders and the cadaveric lesions to which +it gives rise. The typhoid fever, we mean the real one,—for there are +other intestinal exanthematic fevers which simulate it,—always localize +on the small intestines a pustulous exanthem, and in the typhus of the +ox, this pustulous exanthem and the ulcerations by which it is +succeeded, are frequently wanting.</p> + +<p>The real typhoid fever springs up in every country under the influence +of local causes, and is not in the same degree infectious and contagious +as the typhus proper. In fine, the typhoid fever smites many species of +animals—the horse, the pig, etc., without transmitting its contagion +with the same intensity.</p> + +<p>The contagious typhus of the ox appears to be more especially proper to +that animal; for in those latitudes where it developes itself other +animals are not affected by it.</p> + +<p>For these reasons, then, to which we could easily add many others, we +consider the typhus of the present epizootia a special and distinct type +of typhic diseases, and differing from the <span class='pagenum'><a name="Page_196" id="Page_196">[Pg 196]</a></span>typhoid fever: it is the +highest expression of its class, and occupies the first degree in the +scale of infectious typhic diseases. Next to it we should place the +typhoid fever, which we admit is not often found in the ox. But +veterinary pathology is still less understood than human pathology, and +typhoid fever may perhaps be recognised in those diseases which the +former science has described under the names of <i>adynamic</i> and <i>ataxic +fevers</i>. Besides, a persistent research among the veterinary memorials +and reports might possibly enable us to discover some instances in which +the real typhoid fever in the ox had been traced, apart from the +epizootic conditions. Here is an instance of it:—</p> + +<p>Gellé, in vol. i. page 245 of the <i>Pathologie Bovine</i>, quotes the +following abstract which had been forwarded to him by one of his +brethren, on the dissection of an ox, which was made on the 10th of May, +1824:—</p> + +<p>"<i>Duodenum.</i>—Uniform redness of the mucous membrane, with thickening, +softening, and petechial spots. In the middle portion were discovered +some of Peyer's glands, small <span class='pagenum'><a name="Page_197" id="Page_197">[Pg 197]</a></span>round pustules, whitish at the top, with +a reddish circumference. In some parts contiguous to these pustules lay +ulcerations somewhat extensive, which seemed to be the result of the +softening of the pustules which had preceded them. A dark pus issued +from these ulcerations. The inflammation by which they were attended was +diffused in some places, whilst in others it was circumscribed. In some +parts the intestinal mucous membrane was utterly destroyed. The +mesenteric glands were red and soft."</p> + +<p>Gellé adds:—"I have recorded this interesting narrative, as it may +perhaps serve hereafter to throw light on a point of doctrine."</p> + +<p>The intention which Gellé nurtured at the time, is, we see, now +fulfilled conformably with his object.</p> + +<p>The contagious typhus of the ox not being a real typhoid fever, we shall +not, consequently, be able to borrow from it the preventive virus for +that disease in man. But if these diseases differ, and if it is +difficult, in the present state of science, to assign to them <span class='pagenum'><a name="Page_198" id="Page_198">[Pg 198]</a></span>such +distinct characters as to produce a perfect agreement among all medical +writers, we must, however, admit, that to designate the ox-typhus now +before us by the generic name of <span class="smcap">plague</span>, after the Germans, who +have given it the name of <span class="smcap">rinderpest</span>, would carry us too far +back.</p> + +<p>Let us acknowledge also, that the denomination of <i>contagious typhus</i>, +adopted by the French veterinary doctors, is not, any more than the +designation of <span class="smcap">typhus fever</span>, applied to it by English +physicians, totally free from objection.</p> + +<p>In truth, the various species of typhus whose characteristics we have +already given (see p. 73), are all of them febrile and contagious. +Whoever uses the word <i>typhus</i>, speaks of a contagious and febrile +malady, inasmuch as we cannot conceive typhus without its +accompaniments, fever and contagion. But as the prevailing +characteristic of this infectious disease is, above all, its +<i>contagion</i>, we have preferred to adopt the name of <i>contagious typhus</i>, +without, however, deceiving ourselves as to the value of the +denomination. The final <span class='pagenum'><a name="Page_199" id="Page_199">[Pg 199]</a></span>elucidation has not yet been found for these +diseases; at some future day they will be methodically divided and +arranged, and each of them will then receive a special title, which will +remove from the mind that vague uncertainty which at present we regret.</p> + +<p>But if some faults of doctrine are open to debate, no doubt whatever can +exist in the mind as to the morbid individuality of ox-typhus, or the +general conditions of its pathogenia; and we are able to deduce from the +preceding explanation, the following conclusions as so many propositions +definitively settled:—</p> + +<p>1st. The typhus of the ox is a disease essentially infectious, which is +produced by the absorption of the morbigenous miasma in the air.</p> + +<p>2nd. This typhic miasma is absorbed and engendered by the ox, under the +influence of a number of special deleterious causes.</p> + +<p>3rd. When the miasma has been absorbed and incubation produced, the +disease itself is but a supreme effort of nature—a struggle between the +vital forces and the morbid <span class='pagenum'><a name="Page_200" id="Page_200">[Pg 200]</a></span>evolution of the poison, in order to guard +and defend life against the danger which threatens it.</p> + +<p>4th. A malady essentially general, <i>totius substantiæ</i>, it directs its +action, in different degrees, over the whole structure, but chiefly on +the nervous centres, on the organs of respiration, and on the digestive +apparatus.</p> + +<p>5th. Its progress is regular; to the latest period of incubation it +succeeds that of the general poisoning of the blood—that of the pyrexia +of general fever—which for a time stops up all the secretions. Then, +the morbid flux is localized according to particular predispositions: +either on the nervous centres, when the animal is struck down at the +outbreak; or on the lungs, when the respiratory derangements become the +leading symptoms; or on the digestive channels, when the train of +typhoid phenomena is observable.</p> + +<p>6th. The period of acute inflammation, which had dried up the sources of +secretion, gives place to that of the depurative and critical +exhalations or secretions; from every mucous membrane, from every +outlet, there issues a mucous discharge, which at first is thin <span class='pagenum'><a name="Page_201" id="Page_201">[Pg 201]</a></span>and +clear, but afterwards becomes thick and purulent, and endowed with the +most infectious properties. The intestinal mucous membrane, smitten with +a particular lesion, becomes the seat of a flux extremely copious and +intolerably fetid. Gases, and occasionally purulent deposits, are +developed in the cellular tissue beneath the skin.</p> + +<p>7th. The organism or physical frame, disturbed in the very centres of +life, undergoes a general transformation, a kind of organic +decomposition beforehand, and all the symptoms of reaction are followed +by a period of wasting atony and adynamia, which usher in dissolution or +life's extinction.</p> + +<p>8th. Finally, throughout the whole course of the distemper, one special +functional derangement—<i>stupor</i>—has been witnessed as the predominant +symptom, the nervous system being in a manner annihilated in its +functions in consequence of the general infection.</p> + +<p>Such are, in a brief outline, the principal symptoms of this typhus, +which, when once engrafted on the economy, pursues its fatal march, and +no treatment can then arrest its <span class='pagenum'><a name="Page_202" id="Page_202">[Pg 202]</a></span>evolution. As in small-pox, so in +typhoid fever and in most general disorders, Nature for a time must be +allowed to exercise her new functions, which succeed each other in due +course, and which the physician must not stop; for if he did, he would +accelerate death; but he must watch with a vigilant eye, in order to +assist the vital powers.</p> + +<p>The medical man, satisfied with these facts, will therefore abandon the +chimerical hope of finding a specific remedy for such a disease. The +virus once absorbed, the frame will endure, and fatally endure, all the +morbid phenomena which must produce and succeed each other. <i>Against +such a poison no other antidote exists than the poison itself.</i> And this +will be easily understood. What necessity have we for a specific remedy +to resist a distemper, which carries within itself its preventive +treatment? If it germinates and is propagated, let us not accuse Nature +and render her responsible; our own blindness, the lack of a community +of interests among the people, our social institutions, the still +imperfect state of the exact sciences, &c., amply explain how <span class='pagenum'><a name="Page_203" id="Page_203">[Pg 203]</a></span>it is +that we have not yet employed the effectual means we possess, not of +curing it, but preventing it. If we could have our choice between +prevention and cure, should we not naturally take the former?</p> + +<p>Indeed, the sources, the causes which generate the typhic miasma, are +thoroughly well known to us, and these we can avoid. The developed +miasms hang suspended in the air; we may, perhaps, one day destroy them, +if not in the outer atmosphere, at least in the stalls and sheds where +the animals inhale and absorb them. In fine, if we are powerless to +arrest the fell disease when its periods revolve, we may hope at some +future time to act with greater efficiency upon it during its period of +incubation.</p> + +<p>On the other hand, if this formidable disease cannot be stopped in its +progress, does it follow that we should not treat it at all? Certainly +not! Far be such a heresy from our thoughts. What would be the +consequence, if we left to their fate the sufferers from the small-pox, +from typhoid fever, and from typhus itself, instead of watching over +<span class='pagenum'><a name="Page_204" id="Page_204">[Pg 204]</a></span>them with the utmost solicitude? If the physician, the enlightened +interpreter of morbid phenomena, did not direct them with a bold and +fearless hand, but abandoned Nature to her helpless course, why, +necessarily, every patient would die, whereas a large number are now +saved.</p> + +<p>That which is true in the case of man, is likewise true in the case of +animals: we are bound to treat them when they are ill. If to-day we +think it more expeditious and more profitable to exterminate them, we +certainly neglect our duty. We are the sovereign masters of animals; +they are the companions of our toils and pleasures, their lives must be +given to preserve our own; but on their well-being and their happiness +our own well-being and happiness also depend. They will return to us the +sufferings and diseases of which they die a hundred times over. Like +ourselves, they die of consumptive, tubercular, cancerous, eruptive, +typhoid, and parasitical diseases. And who can tell whether they have +not communicated these disorders to man, who was, perhaps, originally +exempt from them; and <span class='pagenum'><a name="Page_205" id="Page_205">[Pg 205]</a></span>whether they do not continually communicate them +to him?</p> + +<p>What noble pages might be written on the close connexion which exists +between all organized beings, both physically and morally! Let us love +these animals, let us treat them with kindness, and all our other +qualities will be raised by so doing.</p> + +<p>But as a man must belong to the time he lives in, we will take up for a +moment with the doctrines of the economists; we will tolerate the +extermination of diseased animals, as a painful necessity. Our duty is +to seek in the study of the diseases of animals <i>and in their cure</i>, the +cure of the disorders which afflict the human species. We shall, +therefore, now proceed to consider the subject of the treatment of +horned cattle, both as relates to preventive and curative medication.</p> + +<h4>FOOTNOTES:</h4> + +<div class="footnote"><p class="noin"><a name="Footnote_O_15" id="Footnote_O_15"></a><a href="#FNanchor_O_15"><span class="label">[O]</span></a> Mr. Simonds has for three months had under his observation +a cow which has lived with impunity among animals sick and dying of the +typhus. And a young calf did not contract the disease for more than +three weeks.</p></div> + +<div class="footnote"><p class="noin"><a name="Footnote_P_16" id="Footnote_P_16"></a><a href="#FNanchor_P_16"><span class="label">[P]</span></a> Another instance of the fatal effects of the terrible +disease now ravaging our flocks and herds of cattle, and resulting in +the death of a veterinary surgeon, has just occurred in the town of +Sudbury, Suffolk. +</p><p class="noin"> +Last week the epidemic made its appearance in the stock-yard of Mr. +Ruffell, farmer, Melford, and the cases were attended by Mr. Robert John +Plumbly, veterinary surgeon, Sudbury. On Thursday a cow, which was +evidently suffering from the disease, was brought out and shot by Mr. +Plumbly, who afterwards made a partial <i>post-mortem</i> examination of the +carcase. In doing so with a small scalpel his shirt-sleeves became +saturated with blood, &c. from the animal. He returned home, and the +same day was attacked with sickness and acute pains in the head and +chest, accompanied with a soreness in the bones generally. On the +following day he appeared somewhat better, and was able to attend to his +duties, but became worse towards evening, and was confined to his house +on the following day. He considered that he was merely suffering from +the effects of a severe cold, and did not call in medical assistance +till Saturday night. He slept well that night, and seemed somewhat +better on Sunday morning. About two o'clock in the afternoon he got out +of his bed to have it made, when he appeared comparatively strong and in +good spirits; but almost immediately afterwards he was taken in what +seemed to be a fit, and expired in a few minutes, before the surgeon, +who only lived next door, could come to his assistance. It was thought +that death had resulted from apoplexy, and a medical certificate to that +effect was given. Rumours, however, soon becoming current that Mr. +Plumbly's death was caused by the cattle plague, the borough coroner (R. +Ransom, Esq.) directed a <i>post-mortem</i> examination to be made. But, by +this time, so rapid was the spread of the virus through the system that +the body appeared perfectly plague-stricken, and by Tuesday morning, +when the surgeons arrived to examine it, and it was taken out of the +coffin, the corpse scarcely retained the semblance of a human being, the +head and trunk being much swollen and black in colour, the features +quite undistinguishable, and all the flesh converted into a putrid +jelly-like mass. The tissues were completely disintegrated, so that it +was utterly impossible to make any examination.</p> + +<p class="noin">An inquest was held on Tuesday afternoon, at the court room, Town Hall, +before the coroner, R. Ransom, Esq., and a jury; Mr. Joseph Barker, +chemist, being chosen foreman. The mayor (S. Higgs, Esq.) and other +gentlemen were present during the whole of the inquiry, which lasted +four hours. +</p><p class="noin"> +The jury went and viewed the body, which lay in an outhouse, but were so +overcome with the fearful spectacle that they were permitted by the +coroner to retire to partake of stimulants before they could further +proceed with the inquiry. +</p><p class="noin"> +The first witness called was Mr. William Brown, veterinary surgeon, and +partner with the deceased, who deposed to having gone with him to Mr. +Ruffell's farm at Long Melford, on Thursday last, to examine several +cows down with the cattle plague. One was brought out and shot by the +deceased, who proceeded to examine the intestines and viscera, which did +not present the appearances usually observable in advanced stages of the +disease, there being but slight ulceration of the coats of the stomach +and bowels. The lungs were not examined, as the deceased had only a +small scalpel with him. In making incisions in the body the +shirt-sleeves of the deceased became covered with blood, but he did not +prick or cut himself. +</p><p class="noin"> +Henrietta Dansie, nurse, was examined, and said that deceased had been +suffering from boils on his right arm, one of which she had poulticed on +Wednesday, the day before he had examined the diseased animal. He +removed the poultice himself, but declined to put on a plaster as the +place was a small one, although not healed. He changed his linen on his +return from Melford; but the same afternoon he was taken with sickness +and vomiting, and complained of acute pains in his head and bones. On +Sunday afternoon, shortly before he died, he wished to have his bed +made, and got out and stood whilst it was being done. He then complained +of faintness, and got into bed again, and witness to revive him washed +his face and hands; in doing so she observed that the nails of one of +the hands which had lain in the bed were turning black. She was about to +give him some pills when she noticed a sudden change come over him; and +thinking he was going to faint or have a fit, she rang for assistance +and went herself for the doctor, who, being from home, another surgeon +residing next door was called in, but by this time the unfortunate +gentleman was quite dead. +</p><p class="noin"> +Mr. Maurice Mason, surgeon, said he was called in to see the deceased +the night before he died, and visited him again on Sunday morning, and +ordered him a lotion and leeches for his head and effervescing drinks +(the leeches were not applied). From the appearance of the body and the +evidence which had been adduced, witness was of opinion that the death +of the deceased was caused by the absorption of poisonous virus from the +dead beast. +</p><p class="noin"> +Mr. W. B. Smith, surgeon, gave similar evidence, and added that the +tissues of the body were so disintegrated that it would have been +utterly impossible to have made a <i>post-mortem</i> examination. +</p><p class="noin"> +After half an hour's consultation the jury returned a verdict, "that +deceased died from the effects of the absorption of virus or poison into +his system upon the occasion of his making a <i>post-mortem</i> examination +of a cow which had died from a certain disease called the cattle +plague." +</p><p class="noin"> +The sad occurrence has caused much sensation in the town, the deceased, +who was only 23 years of age, being well known and much respected.</p></div> + + +<div class="footnote"><p class="noin"><a name="Footnote_Q_17" id="Footnote_Q_17"></a><a href="#FNanchor_Q_17"><span class="label">[Q]</span></a> "Appel à des Expériences dans le but d'établir le +Traitement Préservatif de la Fièvre Typhoide et des Maladies +infectieuses inrécidivables, par l'inoculation de leurs produits +morbides." Memoire lu à l'Institut, le 8 Octobre, 1855. Inséré dans la +Gazette Hebdomadaire de Médecine. Paris.</p></div> +<br /> +<br /> +<br /><span class='pagenum'><a name="Page_206" id="Page_206">[Pg 206]</a></span> +<br /> + +<hr /> +<br /> +<h2>CHAPTER IV.</h2> + +<p class="cen"><i>Treatment and Cure of the Ox-Typhus.</i></p> +<br /> + +<p>In now addressing ourselves to the treatment, and, as far as human +agency can effect it, to the cure, of this insidious distemper, we +cannot conceal from ourselves, that this is the most difficult, the most +delicate, and, at the same time, the most important division of our +work; for it is to this part, above all, that attention will be +directed. This portion of our task, therefore, will prove especially +arduous; and nothing can give a better notion of the difficulties we +shall have to encounter than the many fruitless attempts which, for +several months past, have been made to overcome them by many ardent +inquirers, stimulated by the best possible intentions.</p> + +<p>This, then, is the moment—if we may be allowed the metaphor—to take +the bull by the horns; and we do so without hesitation. If, like so many +others, we are baffled and overcome in this unequal struggle—if our +<span class='pagenum'><a name="Page_207" id="Page_207">[Pg 207]</a></span>strength is not on a level with our desires—we trust we shall be +pardoned.</p> + +<p>Several paths leading to the same end may be followed in this exposition +of the treatment of ox-typhus. After mature reflection, we shall adopt +the one, which will allow us to take the disease at its birth, <i>ab ovo</i>; +to study it in all its phases, in its first and second causes, and then +in the successive periods of its development.</p> + +<p>In this manner, we shall be able to give an account of each fact of real +importance mentioned in the foregoing pages, and to comprise within the +treatment whatever is connected either directly or indirectly with the +disease.</p> + +<p>Thus we will relate in so many separate articles,—</p> + +<p>1st. The means and measures to be employed to meet and resist the first +local causes which may generate the typhus, then the secondary causes +which serve to propagate it.</p> + +<p>2nd. The means of preventing the spread of the disease to animals still +in good health.</p> + +<p>3rd. The means of treating it at its different <span class='pagenum'><a name="Page_208" id="Page_208">[Pg 208]</a></span>periods, from the period +of incubation to that of its decline.</p> + +<p>4th. Finally, we shall insert the laws and sanitary regulations which +have been published in England relative to this disease.</p> + +<p>As will be seen, by adopting this method, the whole matter will be +considered consecutively and in regular order; and the reader will +understand that when such a phase of the malady is developed it is +because the preceding one, which is the cause of it, has not been +effectually contended with.</p> +<br /> + +<p class="cen">I.</p> + +<div class="blockquot"><p class="hang" style="margin-left: 2em;"><i>Means and Measures to be employed to resist the Causes of +the Contagious Typhus of the Bovine Species.</i></p></div> + +<p>We have shown fully and explicitly in what countries of the globe, and +in what particular conditions, the typhus is generated among oxen. We +know that this dire disease has its focus on the banks of great rivers +or lakes, which are periodically overflowed, and on which is deposited a +slime teeming with organic <span class='pagenum'><a name="Page_209" id="Page_209">[Pg 209]</a></span>matter; in marshy plains, where the same +natural impurities are fostered; and that these first hotbeds of the +evil are found in China, in India, in America, in Africa, as well as on +the shores of the Black Sea. A spirit of observation which delights in +measuring the phenomena of nature with the contracted compass of its own +short views and conceptions, could alone have imagined that the +ox-typhus was only to be found originally in the steppes of Hungary and +Russia, and that the bovine species of those countries, thanks to a +special organization, was alone capable of generating the typhus.</p> + +<p>Since we know, then, in what conditions this disease is developed, and +especially in what manner it is propagated in Europe, it is not +impossible now, when nations are united by the means of quick and easy +communication, by commercial treaties, and by the mutual relations of +science, to examine what measures might be taken to modify and control +these conditions. A commission formed for this purpose, a scientific +congress, would be able to make on the spot a study of all the +<span class='pagenum'><a name="Page_210" id="Page_210">[Pg 210]</a></span>circumstances which favour the development of typhus, and the result of +their reports would enlighten the peoples as to the causes which produce +it and from which they are first to suffer. They would be recommended to +choose as pastures the healthiest places, to withdraw their cattle at +certain seasons from those plots of ground which are baleful to them; +new systems of agriculture would be planned and tried, &c. These +questions being carefully examined, might lead to important results; nor +can we understand how, in the age in which we live, the same +indifference and apathy as prevailed in the past should be maintained in +presence of the positive and permanent causes of this infectious +disease, whose contagion, as we now see by many proofs, may extend at +once to so large a portion of Europe. There is now something to be done +in this matter; it is the duty of the governments to deal with it +effectually, and to take serious measures to destroy the evil radically, +if radically it can be destroyed, and, if not, to alleviate its +pernicious effects as much as possible.</p> + +<p>Moreover, many breeders of cattle have not waited until now to guard +against some of the <span class='pagenum'><a name="Page_211" id="Page_211">[Pg 211]</a></span>first causes of the typhus: already they give the +animals rock salt, ferruginous and arsenical preparations, but all this +is done without method, and according to each man's will and pleasure. +It would, therefore, be necessary to institute regulations, and to see +them carried out and practised under the superintendence of public +functionaries, armed with sufficient power and authority.</p> + +<p>These measures having been taken, others no less indispensable ought to +follow. They should determine for the herds of cattle intended for +exportation, the ways and channels they must travel by to go to any +central part or to any railway station; and there the inspectors on duty +should mark every animal that passes out of the district he is leaving. +Heavy penalties should be inflicted on all who might infringe these +rules.</p> + +<p>These precautions would contribute in part to arrest the propagation of +the complaint; but there is another measure more radical and effectual, +which should be taken in order to prevent its extension—we mean +inoculation, which has met with complete success in some of the +governments of Russia.</p> + +<p><span class='pagenum'><a name="Page_212" id="Page_212">[Pg 212]</a></span>Thus we see, there are powerful means of withstanding the production of +the disease in its focus, or generative bed, and likewise its extension +among the herds of neighbouring countries; and these latter might render +them in some sort obligatory, by refusing most rigidly to admit to their +markets, as in Italy has sometimes been done, every head of cattle which +was not marked as inoculated or which was not furnished with a permit of +health.</p> + +<p>It is easy to conceive that those countries wherein the ox-typhus has +its birth, and for which the breeding of cattle and their exportation +are a great source of wealth, would soon feel that they are more +interested than any other in stifling the contagion in its focus, and in +affording to those countries that receive their herds, every security +and guarantee which they have a right to expect. Interest in this case +coming to the help of common sense, very satisfactory results would in +course of time be obtained.</p> + +<p>Moreover, we are conscious that we are here dealing with very +complicated questions; for, though in a book they may seem simple and +easy, their application is a matter of extreme <span class='pagenum'><a name="Page_213" id="Page_213">[Pg 213]</a></span>difficulty. We know too +well that these preventive measures for protecting animals will meet +with many obstacles, and only be adopted at last with tardy reluctance, +since man himself continues in some respect indifferent to the causes +which spread about the fearful epidemics to which he falls a victim in +consequence of his neglect.</p> + +<p>In truth, it is well known that the cholera of the present day—that +much more serious <i>plague</i>—had its origin on the banks of the Red Sea, +amidst the infectious miasmata developed near Mecca, where thousands of +pilgrims who had died of fatigue and privation, and hundreds of +thousands of sheep butchered and religiously offered up in sacrifice, +have, beneath a torrid heat, generated the choleraic miasma, which +formerly was supposed to be produced exclusively on the banks of the +Ganges. This fact duly ascertained and proved, we might suppose that the +governments of the different nations among which the cholera is about to +extend its ravages, were indignant and had complained at thus being +smitten with a scourge, due to the careless ignorance and sordid avidity +of <span class='pagenum'><a name="Page_214" id="Page_214">[Pg 214]</a></span>some official of the Turkish Government. But we should be mistaken.</p> + +<p>No! every one hoped at first that he, at least, would be spared by the +contagion, and the authorities did nothing to resist the evil but adopt +the old course of <i>quarantine</i>—a remedy more illusory now than ever, +since the nations are in constant communication, either in their own +persons or by the exchange of their commodities; and consequently, the +epidemic is pursuing its invading course from week to week.</p> + +<p>That which is being done for the cholera gives us a scale by which we +may estimate the efforts which will be made to arrest the generation and +the contagion of the cattle typhus.<a name="FNanchor_R_18" id="FNanchor_R_18"></a><a href="#Footnote_R_18" class="fnanchor">[R]</a></p> + +<p>We are certainly bound to resist the introduction of horned cattle +tainted with typhus; but in the conditions amidst which they live, some +of them may bear the seeds of the <span class='pagenum'><a name="Page_215" id="Page_215">[Pg 215]</a></span>distemper, even whilst they appear in +perfect health, and therefore able to endure the fatigue of a long +journey.</p> + +<p>Now, in order to avoid exciting the incubation of the typhus during +their transit either to Finland, Holland, France, or England, it must +never be forgotten that these animals are gifted with a nervous +sensibility of wonderful acuteness, joined to the weakest vital +resistance. Care must be taken to husband their strength, to give them a +choice distribution of food easy of assimilation; barley-meal, or other +grains, must be mixed up with their drink; they must be protected from +the changes of weather; they must have room enough and air enough in the +locomotive stalls on the railway trains and on board ship.</p> + +<p>We pass over in silence the hygienic measures to be taken in order to +keep these vehicles of transit in a proper sanitary state: the sanitary +police regulations inserted further on will make them sufficiently +known.</p> + +<p>All these measures having been taken to meet and withstand distant +causes and dangers, let us now direct our attention to those local +causes which strike our eyes, and which <span class='pagenum'><a name="Page_216" id="Page_216">[Pg 216]</a></span>likewise have their share of +influence in propagating the disease. Thus, whenever an inclement season +comes to deprive the herbivorous animals of sufficient pasture, or to +deteriorate its natural qualities, we are bound to remedy this change, +and to increase the cares we devote to them; for these frail and +helpless creatures, immediately feel and suffer from the effects of a +sustenance less than usually restorative. Under such circumstances, we +must make exceptional sacrifices; when they return from feeding on the +grass, we should give them some additional fodder, or roots of a +generous quality. We must imitate the regimen used in the country of the +steppes, by adding to their forage a solution of marine salt, or a +solution of sulphate of iron. Day by day we must give to the weakest and +least fed cattle, a ration consisting of bruised oats, pounded juniper +berries, gentian, sulphate of iron, and carbonate of soda.</p> + +<p>For, if we neglect to take those measures which are required to prevent +among herbivorous animals the development of those ordinary epizootias, +which every year are generated on our own soil, they will certainly +afford a <span class='pagenum'><a name="Page_217" id="Page_217">[Pg 217]</a></span>favourable seat to the typhic miasma transmitted by foreign +animals, or exceptionally generated by themselves. These cares and +attentions must be greatly increased, when the foreign epizootia, has +spread itself, as in the present instance, among our flocks and herds. +Then, indeed, we must be careful not to load these creatures with +pampering food for the purpose of fattening them. For it may be +profitable, and the breeder may plume himself, on having produced an +adipose monstrosity to such a degree as to bury, for instance, a pig's +head in the fleshy exuberance of his thorax; but such a derogation from +the laws of nature borders closely on disease, and assuredly such an +unnatural accumulation, predisposes the glutted animals to epizootic +diseases in general.</p> + +<p>The water given them to drink must be attended to with particular +solicitude. It should never be drawn up from ponds or stagnant rivers. +The animals kept in the pasture grounds should always find at their +disposal, in receptacles intended for their use, a supply of pure fresh +water.</p> + +<p>After these precautions with respect to their food and sustenance, +attention must next be <span class='pagenum'><a name="Page_218" id="Page_218">[Pg 218]</a></span>directed to the hygienic conditions required by +the animal. Every morning he should be cleaned, washed, brushed, and +dried; what is every day done for the horse must now be done for the ox. +These unusual cares will be most salutary to him, and greatly increase +his vital resistance.</p> + +<p>The animal thus protected in his food and particular necessities, +attention must next be directed to the stalls and sheds. Over-crowding +must be carefully avoided; the proper cube of air for breathing must be +measured out for each head of cattle; every day the latter must be +carried out into the open air; the floor of the stall or shed must first +be thoroughly cleansed and washed out, after which it must be sprinkled +with a solution of chloride of lime. If the stall is not well aired, a +little straw should be burned on the ground, to improve the atmosphere, +or else branches of resinous trees, or juniper berries may be used. In +some cases aromatic fumigations of sage, rosemary, or mint, boiled in +water, are employed, the balsamic vapours which arise therefrom being at +once tonic and purifying. During the night a tub, containing pitch and +<span class='pagenum'><a name="Page_219" id="Page_219">[Pg 219]</a></span>tar, should be left in the stall, or a large piece of camphor should be +suspended from the ceiling. Vinegar may be spilt on a piece of red-hot +iron, or powder of sulphur may be burned into sulphuric gas and diffuse +its vapours through the stall or shed. This excellent parasiticide may +perhaps be equally endowed with anti-typhic properties.</p> + +<p>Finally, when this fatal epizootia is ravaging the country, every farmer +and agriculturist must carefully abstain from mixing with his herds any +cattle which have been bought either at fairs or markets; he must take +care, conformably with the directions issued by the Privy Council, (to +which we refer the reader for more ample details,) to avoid all contact +both direct and indirect with horned cattle tainted with the typhus, as +he might himself become an instrument of the contagion.—Let him never +forget that to take as the guide for his actions in these times of +calamity his private and personal interest, is the greatest crime a man +can commit. Let him strive, therefore, to assist the authorities in the +measures which they have taken for the interest of all.</p> +<br /> + +<p class="cen"><span class='pagenum'><a name="Page_220" id="Page_220">[Pg 220]</a></span>II.</p> + +<p>Now that we have examined the measures which prudence directs us to take +to defend ourselves against the causes which produce and propagate +typhus, let us think of the means of preventing it, when the contagion +threatens to diffuse itself over a whole kingdom, as at present it is +doing in England.</p> + +<p>When, on the 19th of last June, it was believed that the typhus or +Cattle Plague, as they continue to call it, had effected its invasion in +England, the Government, informed by professional men of the serious +danger to which the interests of the country would be exposed, if the +disease should spread, might have considered this distemper not as a +question of private interest, but as one of public and national concern. +It might at the outset have given to this epizootia all the significancy +of a public calamity, have looked upon it as the invasion of an enemy +threatening to destroy its territory, and have employed every possible +means to stifle it at its birth.</p> + +<p>We well know that the English Government, derived as it is rather from +political <span class='pagenum'><a name="Page_221" id="Page_221">[Pg 221]</a></span>than from religious and social changes, is at once +monarchical, aristocratic, and partially democratic, and for that reason +embarrassed in its working by so many wheels. Its authority is scattered +and divided, whilst the respect ascribed to the prerogatives of each +distinct public power is the safeguard of the State. In the absence of +both Houses during the recess, it could take no resolution as to ways +and means; for the difficulties on this unhappy occasion, we cannot too +often repeat it, are reduced to a question of money. Deprived of the +requisite authority, it was unable to do more than exhume the old laws +on the matter and ordain new ones. And yet, the impotence of the +Government was not perhaps so great as is imagined; for whilst it +suffered the typhus almost unmolested to devastate the country, it very +justly, and in the name of the public interest, took vigorous and +effectual measures to stamp out another epidemic—the rash and insane +conspiracy of the Fenians. It stood still and would not authorize +domiciliary visits in stables and stalls, nor the seizure of sick +animals, but it did not falter a moment at the domiciliary visits and +incarceration of insurgent citizens <span class='pagenum'><a name="Page_222" id="Page_222">[Pg 222]</a></span>meditating mischief, so that in +this instance, the privilege of immunity has been given to the brute +creation. Everybody, both in England and out of England, admires their +vigour and despatch in stifling the insurrection in its bud. But why not +act with equal promptitude in the case of an epizootia?</p> + +<p>Arming itself, in this manner, in the public interest, and with +sufficient power, the Government might have appointed an executive +commission, with the Lord Mayor as president. Such a commission would +have applied itself at once to the consideration and studious +examination of the subject in all its bearings, and would have proposed +prompt and energetic measures, which the Government, with equal +despatch, would have confirmed by giving to them the authority of law, +as they have since tardily done. A fund, which, for the wealth of +England, would not have been considerable, 250,000<i>l.</i>—the cost of a +few Armstrong guns—might have been placed at the disposal of this +Board, to enable its directors to meet and provide for, without delay, +every just claim and want arising from the scourge.</p> + +<p>An auxiliary commission, exclusively medical, <span class='pagenum'><a name="Page_223" id="Page_223">[Pg 223]</a></span>and consisting of medical +and veterinary doctors, might have been formed conjointly with the +former, and every preventive measure, considered by them as necessary to +stamp out the complaint at the outbreak, after it had been proposed by +the medical board, and submitted to the executive commission, and by +them to the Home Secretary, might have been acted upon by law within +twenty-four hours.</p> + +<p>Taken unawares, and the mode of treating the sick animals not being +known at first, they would have been reduced to the cruel necessity of +exterminating at once all tainted cattle, as well as those belonging to +tainted herds, but not without compensating the owners of those +cattle.<a name="FNanchor_S_19" id="FNanchor_S_19"></a><a href="#Footnote_S_19" class="fnanchor">[S]</a></p> + +<p>They would have sent two physicians to Russia and Hungary, to observe +and study the preventive and curative medication, especially their mode +of inoculation, and thanks to the rapid locomotion of these times, +twenty days would have been sufficient for this foreign <span class='pagenum'><a name="Page_224" id="Page_224">[Pg 224]</a></span>exploration. +The physicians constituting the medical board should have been +authorized to seize any beast tainted with the typhus; a company should +have been charged to collect and keep ready for the public service, at +the four quarters of London, an ample retinue of horses, closed +carriages, and working men, to convey at all hours of the day and night +the carcases of the slaughtered animals to the respective spots, where +long and deep trenches had been dug to receive them. Each carcase before +burial to have been well sprinkled with chloride of lime.</p> + +<p>By taking this course, every one's interest would have been respected, +as much as can be desired when a great calamity threatens a country; +besides, in doing so, the present ministers would but have followed the +example of the Government (with regard to compensation), during the +epizootia of the eighteenth century. The proprietors who had thus +received, not the full and absolute price, but a sum sufficiently +remunerative for their sacrificed cattle, would have assisted the +authorities, and thereby would have served the common interest, because +their sick cattle, <span class='pagenum'><a name="Page_225" id="Page_225">[Pg 225]</a></span>perishing every hour within their stalls and sheds, +were no longer a real source of embarrassment and ruin. They would not +have been obliged to drive them to market to get what they could out of +them and disencumber themselves. The most active cause of the contagion +would by this means have been prevented.</p> + +<p>This allowance having been made for the most pressing dangers, attention +should next have been directed to a matter no less important—we mean +the treatment and cure of this distemper; for we will never admit that +England can have fallen back a century, and that whilst those +enlightened men—Malcolm Flemming and Layard—proposed and tried to cure +and prevent ox-typhus in 1757, we, in 1865, shall have been reduced to +the horrible alternative, the repugnant barbarity, of the general and +indiscriminate extermination of the tainted cattle.</p> + +<p>Whilst, therefore, the treatment of the typhus would have been studied +on the spot, and the most urgent measures would have been taken to +withstand the propagation of the evil, they would have established, a +few <span class='pagenum'><a name="Page_226" id="Page_226">[Pg 226]</a></span>miles from London and on the northern side, in the direction of the +great cattle market, a number of hospitals or sanitariums, and, as far +as possible, within a park. These hospitals, constructed of wood, +containing, besides stables and sheds, a slaughter-house, a +dwelling-house for the staff of employés, a laboratory stocked with all +the physical and chemical instruments required, &c., would in two or +three weeks have been sufficiently prepared to receive a certain number +of cattle.</p> + +<p>Provided with these advantages and opportunities, a permanent stage of +operation would have been raised on which trials and experiments might +have been made with every chance of fruitful results. In these +sanitariums, for instance, the most practical physicians and +veterinarians might have entered upon a systematic course of treatment, +dividing the bovine patients into classes, according to their periods of +disease, their age, &c.; and trying some particular mode of treatment, +some remedy considered as effectual, alternately, upon each of these +classes of tainted cattle. These experiments, having been made under +circumstances so favourable, would have <span class='pagenum'><a name="Page_227" id="Page_227">[Pg 227]</a></span>enabled the faculty to +establish a medical basis, which, if not infallible, would have been +relatively efficacious, and might have saved a large number of the +infected animals.</p> + +<p>Whilst thus fixing their attention on the cure of the sick animals, +these experimentalists would have carefully studied and practised the +preventive treatment by inoculation, availing themselves both of +Layard's hints and recommendations and of the practical knowledge +acquired by the medical expedition to the steppes, which would by that +time have returned from their mission. They would have selected animals +smitten with the genuine typhus, of the typhoid and intestinal form, in +<i>the third period</i>, whilst the depurative and critical secretions are +running from the mucous membranes; they would have gathered the virus +from its springs of infection or from its purulent subcutaneous deposits +or from the serum of the blood.</p> + +<p>On the other hand, they might have chosen four heifers, of good +constitutions and healthy, and these they might have prepared, according +to Layard's advice, for inoculation, by a special treatment, and by +hygienic and medical cares. <span class='pagenum'><a name="Page_228" id="Page_228">[Pg 228]</a></span>On some of these the inoculation would have +been made near the tail, according to the subcutaneous process, with a +lancet charged with typhic virus; on others, a crucial incision, or +cross-cut, would have been made on the crupper. But, to speak truth, we +cannot do better than Layard, whose ingenious treatment, with all due +deference to a certain veterinarian of our day, deserves a very +different epithet than that of being amusing.<a name="FNanchor_T_20" id="FNanchor_T_20"></a><a href="#Footnote_T_20" class="fnanchor">[T]</a> Layard says:—</p> + +<div class="blockquot"><p>"That nothing may be omitted which in any shape can +contribute to the success of inoculation, due attention +should be paid to the constitution and state of the beast, +<span class='pagenum'><a name="Page_229" id="Page_229">[Pg 229]</a></span>no less in this practice on the cattle than on the human +species. Undoubtedly the young, healthy, and strong bid +fairer for a good issue than the old, sickly, and feeble; +each of these different constitutions demand a particular +treatment, even in the method of preparation; and however +trifling it may seem to many—the urging a necessity of +preparation—I will venture to affirm that I have seen +excellent effects arising from a rational preparation, and +fatal events from want of preparation. I have likewise been +witness of unfavourable turns, merely from an injudicious +preparation.</p> + +<p>"The beasts which are sanguine require moderate bleeding; +those that have but a small share of blood must have none +drawn. The strong must, besides moderate bleeding and +purging, be kept on light diet and their body kept open. +Thus, scalded bran, mixed with their hay and chaff; will +cool them. The weakly, and such as are inclined to scour, +must be kept on dry fodder, and have peas and beans given +them to strengthen them. A mess of malt, or a quart of warm +ale, with a few spices, will be very suitable for them.</p> + +<p>"Whatever diseases the cattle be affected with, if time will +permit, they are first to be removed.</p> + +<p>"The cattle to be inoculated are first to be well washed, +rubbed dry, and then curried, to remove all the filth from +the hair and skin. Then they are to be placed in a spacious +barn or stable, where the air is temperate and no cold can +come to them. There they are to be prepared according to the +direction already given, foddered with good sweet hay, and +watered with clear spring water; and if the distemper be not +near they may be turned out into the air, near the barn or +stable, and may stay there a few hours in the middle of the +day.</p> + +<p>"When it appears that the cattle are in perfect health, free +from any infection or other disease, brisk and <span class='pagenum'><a name="Page_230" id="Page_230">[Pg 230]</a></span>lively, +neither costive nor scouring, and chewing their cud, then +the operation may be safely undertaken, and henceforth they +must be confined to the barn.</p> + +<p>"Since there is observed to follow the greatest flow of the +contagious and putrid particles separated from the blood, +wherever the infectious matter makes an impression at first, +particular care must be taken not to inoculate near such +vital parts as the heart and lungs, nor near the womb, if a +cow with calf be inoculated; for, though rowels are properly +applied in the dewlaps, to draw off the pestilential humour +from the breast, and in other cases beasts are frequently +rowelled in the flanks,—yet in this operation, as matter is +inserted by these channels into the neighbouring vessels, +those vital parts, or the womb, might become the chief seat +of the disease, and the event prove fatal.</p> + +<p>"To prevent such accidents, human beings have been +inoculated on the arms and legs, and now-a-days the arms are +found sufficient. I would recommend that the cattle should +be inoculated about the middle of the shoulders or buttocks, +on both sides, to have the benefit of two drains. The skin +is to be cut lengthways two inches, deep enough for the +blood to start, but not to bleed much. In this incision is +to be put a dossil or pledget of tow, dipped in the matter +of a boil full ripe, opened in the back of a young calf +recovering from the distemper. It may not be amiss to stitch +up the wound, to keep the tow in, and let it remain +forty-eight hours. Then the stitches are to be cut, the tow +taken out, and the wound dressed with yellow basilicon +ointment, or one made with turpentine and yolk of egg, +spread on pledgets of tow. These dressings are to be +continued during the whole illness, and till after the +recovery of the beast, to promote the discharge; and then +the wound may be healed with the cerate of lapis +calaminaris, or any other.</p> + +<p><span class='pagenum'><a name="Page_231" id="Page_231">[Pg 231]</a></span>"On the third day after inoculation, the discolouring of the +wound, whose lips appear grey and swollen, will be a sign +that the inoculation has succeeded; but the beasts, as +Professor Swenke informs us, did not fall ill till the sixth +day, which answers exactly to the observations daily made in +the inoculating of children. Yet the Professor adds that on +the third day a costiveness came on, which was removed by +giving each calf three ounces of Epsom salts.</p> + +<p>"No sooner do the symptoms of heaviness and stupidity appear +than the beasts must have a light covering thrown over them, +and at night fastened loosely. They must be rubbed morning +and evening, and curried, till the boils begin to rise; warm +hay-water and vinegar-whey must be given plentifully. Should +the beasts require more nourishment, dry meat, such as hay, +with a little bran, may be offered. I should be very +cautious in giving milk-pottage, even after the boils and +pimples had all come out, for fear of bringing on a +scouring. However, this caution is proper, that whenever +milk-pottage be given the vinegar-whey is to be omitted for +obvious reasons. In cases of accident, the same attention is +to be observed in the disease by inoculation as in the +natural way, and the medicines recommended are the same I +would use; but by inoculation there seldom is a call for +any, so favourably does the distemper proceed through its +several stages.</p> + +<p>"The crisis being over, it will be proper to purge the +cattle, to air them by degrees, and to have the same regard +in the management of them as is laid down in the chapter on +the method of cure."</p></div> + +<p>The typhic virus is so highly infectious and poisonous that the first +animals inoculated <span class='pagenum'><a name="Page_232" id="Page_232">[Pg 232]</a></span>would have all died; it would have been necessary to +inoculate successively a number of animals with the virus derived from +the first inoculation, and transmitted from an inoculated animal to a +healthy one, by which means they would have acquired a virus of the +first, second, third generation, and so on. These inoculations having +always been made on four animals at a time; on two of them, the disease +would have been left to take its own course, in order that the +experimentalists might watch its progress and development, and the two +others would have supplied the virus for inoculation.</p> + +<p>At the third or fourth generation, the virus, modified and attenuated in +its infectious principles, would no longer have been mortal in its +effects, as experience has proved in Russia. Then the inoculated +animals, placed under the control of hygienic cares and a few purgative +and tonic medications, would have passed from convalescence to health. +The virus thus attenuated would have supplied the means of a practical +inoculation on a large scale to all healthy animals.</p> + +<p>Proceeding thus, they would, moreover, but <span class='pagenum'><a name="Page_233" id="Page_233">[Pg 233]</a></span>have followed the method +adopted in those times of epidemic and epizootia when the small-pox is +raging. On those occasions, we subject our sick patients to vaccination +or revaccination; we inoculate the variola in our sheep threatened with +the contagion; we pursue the same course in cases of epizootia, of +peripneumonia. And truly, that which it is reasonable to do in one case +may be generalized and applied to a greater number.</p> + +<p>The experiment we have suggested might, perhaps, have been long and +difficult, nay, even costly, but we should have established, after a +certain time, the rational method of this preventive treatment, and have +distributed the same throughout the country. Veterinarians would have +formed in particular districts their centre of operation, in which the +preventive virus might have been produced, and they might have gone from +farm-house to farm-house to inoculate all the cattle within them.</p> + +<p>From these facts and observations made by the physicians, precious +documents would have been derived; and if, contrary to all expectation, +success had not justified every hope, we should have bequeathed to +future generations <span class='pagenum'><a name="Page_234" id="Page_234">[Pg 234]</a></span>facts and experiences which would have been of the +most useful character to them and full of instruction. Thus it is that +science advances and progress is accomplished.</p> + +<p>If all that we have just indicated as a realizable matter had been done, +in effect, England would have afforded in this, as she has so often done +in other cases, a noble example to be followed, and would have acquired +a new title to the admiration of other nations.</p> + +<p>But, unfortunately it has not been so: silence has succeeded to +eloquence at Guildhall, and the meetings at the Mansion-house have +flickered away. That which was held on the 27th of September, seems +likely to be the last of them.<a name="FNanchor_U_21" id="FNanchor_U_21"></a><a href="#Footnote_U_21" class="fnanchor">[U]</a></p> + +<p><span class='pagenum'><a name="Page_235" id="Page_235">[Pg 235]</a></span>The subscriptions which, in spite of all the praiseworthy efforts and +earnestness of the Lord Mayor, did not reach 2000<i>l.</i>, were returned to +the subscribers, so that all the attempts which have been made to +centralize the direction to be given to the various measures have proved +abortive. The plan of forming sanitariums, as well as that of +compensating the owners of cattle, have both fallen to the ground.</p> + +<p>What can we think of such a state of things when we see the ox-typhus +extending its ravages to sheep, and have to fear that the disease will +spread to other animal species? What serious reflections it creates in +our minds, and what awful consequences we might deduce therefrom! But +what would be the use of them?</p> + +<p>Let us add, however, that France, save on the recognised principle of +indemnification, and a more speedy extermination of her tainted cattle, +has shown the same deficiency as to <span class='pagenum'><a name="Page_236" id="Page_236">[Pg 236]</a></span>the means of treatment as England; +whilst we have the consolation of attributing this impotence on the part +of this country to the fact that the outbreak of the epizootia has +occurred during the Parliamentary recess.</p> + +<p>It is, therefore, to institutions rather than to individuals that we +must ascribe the impossibility of conquering the difficulties which have +been met, and which at any other time might not have obstructed the +course of things. Far be it from us therefore to accuse of indifference +a great people renowned for their zealous promotion of public interests, +for their charity and inexhaustible philanthropy, whose innumerable +asylums have been opened to every misfortune, who support so many +hospitals and public charities by their voluntary contributions, and +who, in so many calamities, have seen some devoted heroine issue from +her retirement to assuage them. For if the Crimean war produced its lady +beneficent in the person of Florence Nightingale, all of us must allow +that if others had followed the example of Miss Burdett Coutts, who, in +a manner, has stood alone against the storm, by the facilities she has +afforded for treating and experimentalizing on the cattle <span class='pagenum'><a name="Page_237" id="Page_237">[Pg 237]</a></span>smitten with +typhus, the formidable scourge might have been arrested in its focus.</p> +<br /> + +<p class="cen">III.</p> + +<p class="cen"><i>Curative Medication.</i></p> + +<p>We might acquire the means of resisting the general causes which develop +the typhus; we might stop its diffusion, we might even prevent it, by +inoculating the sound and healthy animals, and yet it would be +necessary, none the less, to search for the means of curing it; for, as +in the small-pox, the preventive treatment of which we know, certain +circumstances would arise in the disease which would oblige us to treat +it. And as we are far from being able to resist the generation and +dissemination of this scourge, which reckons almost as many victims as +sufferers, it is important to make known what treatment we can oppose to +the functional derangements to which it gives rise.</p> + +<p>As we have already said, this typhus, when the organism has absorbed its +peccant and infectious miasma, produces a succession of disorders which +become in a manner <span class='pagenum'><a name="Page_238" id="Page_238">[Pg 238]</a></span>temporary functions; it pursues its phases, its +periods; and as the functional derangements differ at these several +epochs from the development of the morbid phenomena, the course of +medicine which is employed to check them cannot always be the same. +Starting, therefore, from practical data, we will attend the disease in +its gradual advance—that is to say, in its distinct periods—and will +afterwards explain certain predominant symptoms, which, owing to their +importance, must likewise fix the attention of the careful therapeutist.</p> + +<p>It will be remembered that we have recognised four periods in the +regular course of typhus:—</p> + +<div style="margin-left: 37%; margin-right: 20%;"><p class="noin"> +1st, a period of incubation;<br /> +2nd, a period of initiation;<br /> +3rd, a period of duration;<br /> +4th, a period of decline. +</p></div> + +<p>But, in the first place, before beginning the treatment, every farmer or +grazier, or cattle-owner, who keeps a certain number of cattle, should +divide his herd into several classes, in order to regulate and methodize +the cares to be given to the sick.</p> + +<p>Thus, he will form a first class, comprising <span class='pagenum'><a name="Page_239" id="Page_239">[Pg 239]</a></span>the animals in a sound and +healthy state, having had no intercourse, either direct or indirect, +with the tainted cattle, and which he will be careful immediately to +isolate and keep apart.</p> + +<p>A second class must be formed of those beasts, which, though as yet +unaffected with the distemper, have, nevertheless, been exposed more or +less directly to its contagion, by living and consorting with them, or +by their contact with other animals, either at fairs or markets, or in +the ships and cattle-trucks on the railway during their transit from one +place to another. The horned cattle composing this latter class must be +carefully watched, and be made the subject of the preventive treatment, +the moment the first sign appears of the working of the incubation.</p> + +<p>A third class must be formed, consisting of cattle actually smitten with +the distemper.</p> + +<p>These divisions of animals being thus settled and separated, will +diminish the labour and the cost of treatment and the liability to +diffuse the complaint, especially when the epizootia begins to lose its +virulence.</p> +<br /> + +<p class="cen"><span class='pagenum'><a name="Page_240" id="Page_240">[Pg 240]</a></span><i>First Period—of Incubation.</i></p> + +<p>We have said that infectious diseases, when once the frame had suffered +the effects of the poisonous miasma, pursued their fatal course, and +that, generally speaking, it was impossible after such infection to +arrest its development. We say generally, for the typhus at the outbreak +of its appearance on a virgin soil sometimes manifests itself in a +benignant manner, then it becomes more destructive, by-and-bye its +pernicious properties decline, and it in some sort goes out of itself. +One would say that the epizootia, like those it smites, has likewise its +peculiarities, its period of initiation, of duration, and of decline. +There are in consequence fixed times or epochs during which the +sufferers afford better scope for our means of action; at a given moment +the attenuated virus, having lost much of its deadly effects, ceases to +produce death, which decline is the real source of the marvellous +successes obtained by certain remedies against the epizootia.</p> + +<p>If it be true that the distemper at its period of duration, and at its +most critical moment, <span class='pagenum'><a name="Page_241" id="Page_241">[Pg 241]</a></span>cannot be fettered, we should not be justified in +asserting positively the same, as respects the period of incubation. +Indeed, we are convinced ourselves, that if ever this disease shall be +clogged in the wheel, <i>if ever its specific remedy shall be discovered, +it will be within the period of incubation</i>, when the economy begins to +struggle with the first phenomena of the poisoning. Be that as it may, +we cannot, in epizootic times, too earnestly enjoin the owners of cattle +to submit their animals to a strict and close inspection, in order that, +when the first signs of incubation appear, they may modify the animal's +usual diet, and attack the disease at its birth, so as to render it +abortive, if the thing can be done.</p> + +<p>At this period we must endeavour to come to Nature's assistance, we must +shake and stir up the economy, we must unseat the morbid functions which +seek to master us, and then the vital force, thus solicited and +stimulated, may sometimes struggle with advantage. To do this +effectually, if the animal is atonic and predisposed to adynamia, if his +internal organs are relaxed, we will strengthen him by administering +every day a stimulating <span class='pagenum'><a name="Page_242" id="Page_242">[Pg 242]</a></span>beverage. If he is confined to the stall we +will give him the open air, and let him graze the fields; which is a +treatment by itself for the invalid animal, so vivifying is the pure air +of the common, and so thoroughly different from the atmosphere which is +pent up within his stall. If the animal is strong, lusty, exuberant with +health, let him be purged once or twice, the purgative to be given at +intervals of twenty-four hours. (We shall give the medical formula in +the chapter addressed to farmers, graziers, &c.)</p> + +<p>This purgation, moreover, will correspond with the theory of those +authors who consider the evacuations as the proper means of delivering +the economy from the infectious miasms which have been absorbed.</p> + +<p>If the beast is plethoric, recourse should sometimes be had to bleeding, +especially in hot and dry seasons, like the one we have recently passed +through.</p> + +<p>These stimulative and depletive medications cannot but be favourable to +the animal, since it will anticipate the treatment to which he must be +submitted a few days later, when the disease shall have declared +itself.</p> + +<p><span class='pagenum'><a name="Page_243" id="Page_243">[Pg 243]</a></span>To this treatment, in some sort preventive, must be annexed an +<i>antimiasmatic</i> beverage, either a <i>permanganate of potash</i>, or a +solution of <i>chlorate of potash</i>, or of <i>arsenic acid</i> in powder, mixed +with some aromatized beverage, or solution of <i>arseniate of soda</i>. These +anti-typhic drinks must be discontinued on those days when the sick +cattle are purged.</p> + +<p>It need hardly be said, that during this period of incubation the +feeding of the cattle must be strictly attended to, and that the animal +must receive unusual hygienic care.</p> +<br /> + +<p class="cen"><i>Second Period, or that of Initiation.</i></p> + +<p>At this period the constitution and temperament of the sick cattle must +first of all be deliberately studied, so as to ascertain fully which are +<i>lymphatic</i>, which are <i>nervous</i>, and which are <i>sanguine</i>. We must +notice the age, the sex, the state of gestation, and make allowance for +any prior complaints to which any of the sick cattle may have been +subject. For if, like certain system-mongers, we reduced the treatment +of all tainted cattle to the same mathematical formula of medication, +that is, either to bleeding or to purging exclusively, <span class='pagenum'><a name="Page_244" id="Page_244">[Pg 244]</a></span>we should +certainly increase the number of victims.</p> + +<p>In this stage of the disease we have to contend with the derangements of +the circulation and secretions. The fever is generally intense, the +blood is inflamed or vitiated, the mucous membranes are dried up; +shiverings, alternations of cold and heat, &c., occur. We must then +mitigate these morbid phenomena either by bleeding or purging. The +bleeding must be more or less copious, according to the strength of the +animal. For, it must not be forgotten that we have several critical +phases to pass through, and if we exhaust the animal by too largely +draining him of blood, we may forfeit the success of the treatment. If +bleeding is considered unnecessary, let the sufferer be purged at once, +by administering either <i>sulphate of magnesia</i> (<i>Epsom salts</i>), <i>or +sulphate of soda</i> (<i>Glauber's salt</i>). These purges to be taken daily, +for two or three days, according to the way they operate. Linseed oil, +mixed in some warm beverage, may be given instead of these, or else a +mixture of rhubarb and calomel, or even a decoction of senna. Preference +should be given to saline <span class='pagenum'><a name="Page_245" id="Page_245">[Pg 245]</a></span>or laxative purges, as, drastic purgatives, +such as aloes or jalap, sometimes concentrate the inflammation on the +narrow parts of the digestive channels.</p> + +<p>In this second stage—the period of initiation—the appetite is +generally gone, the thirst excessive; so that nutritive or solid feeding +must of course be suppressed.</p> + +<p>As for the drinks, they must be cold, consisting of water with +sufficient flour mixed in it to whiten it, and a little vinegar or +sulphuric acid, to acidulate it. A decoction of good hay with some +marine salt, or nitrate of potash; a decoction of pellitory or +wall-wort, of ground-ivy, or whey, or buttermilk, likewise acidulated, +and which the cattle are very partial to, will in every way be suitable +for their use. If the heat of the skin diminishes, and if congestion +appears to settle on the lungs, the drinks must be given warm, +consisting of a decoction of borage leaves, mallows, marsh-mallow, and +pellitory. In these cases, the body must be protected from chills by +overlaying it with blankets, so as to keep the mass of the blood as much +as possible on the surface, and check the tendency it has to load the +internal organs.</p> + +<p><span class='pagenum'><a name="Page_246" id="Page_246">[Pg 246]</a></span>By following these prescriptions, we shall answer all the conditions of +the treatment during the second period. In truth, by the process of +bleeding, we shall have reduced the heat of the fever, and prevented too +great a flow towards the nervous, pulmonary, or digestive centres. The +purgings will have acted with similar effects; and, what is more, they +will have cleared the <i>primæ viæ</i>, and rendered the circulation of the +abdominal apparatus more easy. In fine, the drinks will have contributed +to assuage the violence of the fever. The washing, which must be +effected with a wet sponge passed over the nose, mouth, and eyes, and +then over the skin, which must afterwards be rubbed dry, will be both +useful and pleasant to the sick animal. This cleansing will maintain the +important functions of the skin in due order.</p> + +<p>Some persons have advocated as most efficacious at this period +hydro-therapia, or the Water-cure, in the form of warm and cold +ablutions, vapour baths, &c. This treatment, so bracing by its revulsive +action, and the powerful influence of which we witnessed for several +years in the establishment which we <span class='pagenum'><a name="Page_247" id="Page_247">[Pg 247]</a></span>superintended at Belle Vue, near +Paris, might prove of some service in ox-typhus, especially in the form +of the vapour bath; but it requires so much practice, and so incessant +and watchful a care, that it is needful to have the process attended by +an experienced practitioner.</p> + +<p>We must remark, in addition, that the general state of the animal, and +his desire for food, will show the degree of strictness and restraint +which must be observed in regulating his diet. His instinct must be +taken by us as a guide; and if the drinks rendered nutritive by the +addition of bran, oatmeal, barley flour, or even seed of grass pounded, +are relished by him, we must indulge his desires to some extent, in +order to keep up his strength.</p> +<br /> + +<p class="cen"><i>Third Period, or that of Duration.</i></p> + +<p>At this stage of the distemper we must watch and follow step by step the +symptoms which attend it, and come to their relief.</p> + +<p>All the secretions have now resumed their course; from the mucous +membranes there occurs a copious discharge, first of all serous, then +thick and muco-purulent; the breathing <span class='pagenum'><a name="Page_248" id="Page_248">[Pg 248]</a></span>may be obstructed, the +diarrhœa frequent; the air infiltrates beneath the integument. The +fever is sometimes continuous, sometimes intermittent. We must satisfy +the cravings of the vital powers by administering the same beverages as +in the preceding period. Far from checking the diarrhœa, as some +advise, we must regulate the evacuations by means of laxatives, such as +tartrate of potash, sulphate of magnesia, or sulphate of soda. It is +very essential, indeed, that the mucous membranes of the digestive +channels should be free, and not irritated by the contact of solid +alimentary substances or bilious secretions.</p> + +<p>If the diarrhœa be too frequent or irritating, we must give the +sufferer night and morning a clyster, consisting of bran water.</p> + +<p>At this period we will follow the advice given over and over again by +all the physicians of the last century, and apply cauteries with red-hot +iron, or fix one or two setons either on the dewlap, the neck, or the +thighs, and these issues must be kept open by means of basilicon +ointment. It is unquestionably of the highest importance to promote all +the depurative secretions in animals whose cellular <span class='pagenum'><a name="Page_249" id="Page_249">[Pg 249]</a></span>tissue is choked up +with grease and lymph. Those only have got well in which the running has +been regular and copious, and the wasting of the flesh progressive.</p> + +<p>If the fever is not regular, two pills of sulphate of quinine must be +given, each pill containing one gramme, one pill in the morning, the +other during the day, in order to prevent the fit, which usually takes +place in the evening. If the state of atony, of adynamia, comes on at +this period, <i>acetate of ammonia</i> must be given, from one to six ounces, +in a pint of water, the same to be administered in two doses; only the +acidulous or alkaline drinks must be discontinued, otherwise the acetate +of ammonia would be decomposed in its passage into the digestive +channels. Finally, the eyes, the nostrils, and the mouth must be +frequently washed with an infusion of camomile, or some other aromatic +plant.</p> + +<p>The setons must be kept up very carefully. If the sick animal relishes +the nutritive beverages, let him have a decoction of bread, rice, +barley, or oats.</p> +<br /> + +<p class="cen"><span class='pagenum'><a name="Page_250" id="Page_250">[Pg 250]</a></span><i>Fourth Period, or that of Decline.</i></p> + +<p>At this stage of the disease, in which adynamia predominates, everything +must tend to support the organism. The drinks must be bitter and +stimulating; beer, with plenty of hops in it, with an addition of +powdered Peruvian bark or sulphate of iron, may be given; or a decoction +of this bark, with gentian roots, centaury leaves, and hops; or again, a +beverage may be administered night and morning, made of veterinary +theriacum, of extract of juniper and alcohol; or finally, an infusion of +aromatic plants.</p> + +<p>If the diarrhœa be bloody and fetid, give the animal night and +morning a clyster, consisting of a decoction of Jesuit's bark, adding +thereto a spoonful of powdered wood charcoal, pounded to the finest +powder, and passed carefully through a sieve. If the running ceases, its +return must be excited by injecting in the nostrils a spoonful of +sternutatory vinegar or smelling salts. Finally, the purulent boils must +be opened, and dressed with stimulating ointment.</p> + +<p><span class='pagenum'><a name="Page_251" id="Page_251">[Pg 251]</a></span>At this closing period, which determines the fate of the disease, as we +say, there is a tendency to despair of the cure. Seeing the fatal course +of most attacks, we lose heart, death seems inevitable, and we yield its +prey to its fangs. But let us not despair; let us remember that, in +these febrile infectious diseases, above all, the phenomena must almost +always proceed to the last stage of exhaustion of the vital powers to +render the cure attainable. Some patients, smitten with typhoid fever or +cholera, have owed their lives to the indefatigable tenacity of the +contest <i>in extremis</i> between life and death.</p> + +<p>I still see before me a choleraic patient, whom, during the epidemic of +1849, I had left in the morning at ten o'clock, passing into the cold +period. At five o'clock I returned to see him; the whole family was in +tears, and the sheet had been thrown over the patient's head, as if he +had already breathed his last. Time was precious to me at that fell +season, and I was about to retire, when I applied my finger to the wrist +of the sufferer, and felt a faint pulsation at long intervals. I threw +<span class='pagenum'><a name="Page_252" id="Page_252">[Pg 252]</a></span>my coat off directly, called for flannel and essential oil of mustard, +which I had prescribed that morning. I set the example, and instantly +the whole family helped me to rub the patient in every direction. In a +quarter of an hour the heart quickened and revived, and in less than +half an hour more the circulation resumed its course; at the end of an +hour of this obstinate struggle the vital heat began to show itself—in +a word, the patient was saved.</p> + +<p>We must not, therefore, give up the contest until the death of the +sufferer is fully ascertained; and the same persistency should be +practised in the case of animals smitten with the typhus. If the +circulation slackens, if the skin turns cold, take a piece of wool, coat +it with rubefacient liniment, and rub the animal therewith, more +particularly along the spine. Then give him a cordial drink, and pass +<i>raies de feu</i> over the loins. All these appliances will help to +stimulate the nervous system, and resuscitate the exhausted powers of +life.</p> + +<p>If, at last, we are so fortunate as to overcome the profound adynamia +which has <span class='pagenum'><a name="Page_253" id="Page_253">[Pg 253]</a></span>utterly prostrated the frame, we next shall have to sustain +the sick animal by giving him decoctions of meat with sea-salt, or +sulphate of iron added to it, or a light broth, made with meat and +bread.</p> + +<p>Herbivorous animals, put upon a carnivorous diet, would not generally +endure it, of course; but some of them rather incline to unctuous +beverages, and even to cooked or raw meat. All men know that certain +horse trainers give race-horses a small portion of meat, especially when +the races are coming on, in order to increase their mettle and strength.</p> + +<p>We remember a sheep, which we saw at the Ecole d'Alfort, during our +studies of comparative pathology and the cutaneous diseases of domestic +animals, which manifested a great liking for meat, and even ate it +ravenously like a glutton.</p> + +<p>In convalescence, the animal must be sent into the open air, in some +fold enclosed with bars; he must be taken every day to pasture, each day +increasing the time he is allowed to feed, and gradually he will be left +to return to his usual regimen. But still it <span class='pagenum'><a name="Page_254" id="Page_254">[Pg 254]</a></span>must be observed, that in +this distemper convalescence is long and slow, and very deceitful. A too +substantial course of feeding often revives the inflammation of the +intestines by irritating ulcerations not yet healed, and more than one +animal which had been looked upon as cured has perished in its +convalescence through a lack of watchful attention.</p> + +<p>Herbivorous beasts, therefore, incline to and digest animal food; +consequently, we must give sick oxen meat broths, pure milk, or milk and +water. With these must be mixed wheat straw chopped small, for hay or +even oat straw would swell and distend the stomachs.</p> + +<p>The typhus in this epizootia is not regular in its progress and +development. Frequently the nervous or pulmonary phenomena predominate, +when the treatment, such as we have just explained, must be modified. We +must also bear in mind that nature does not divide a disease into +periods, like those we have adopted to render our exposition of the +symptoms more intelligible and the treatment itself more methodical.</p> + +<p>If the nervous form of the disease <span class='pagenum'><a name="Page_255" id="Page_255">[Pg 255]</a></span>prevails—if the animal shows +alternations of dulness and restlessness—if, pressure on the spine is +very painful—above all, if, in bulls, for instance, there is plethora, +let the bleedings and purgings be increased in order to abate the +nervous erethismus. In this form, the violence of the attack usually +carries off the beast. Should there, however, be any chance of saving +him it will be by employing this medication, which is at once revulsive +and depletive, notwithstanding the well-known fact that bleedings, far +from relieving the nervous system, sometimes aggravate its irritability.</p> + +<p>A general ablution with cold water may be tried in <i>desperate cases</i>. +The animal must then be immediately well rubbed, and covered with wool, +in order to excite a thorough reaction.</p> + +<p>In the pulmonary form of the typhus, but only during the acute stage, +the drinks must be warm and emollient, composed of a decoction of +soothing substances, with mallows, &c.; or one of linseed, to which must +be added some oxymel of squills and opium. The purgatives must be +non-stimulating; and <span class='pagenum'><a name="Page_256" id="Page_256">[Pg 256]</a></span>emetics, freely diluted, for instance, will be +very serviceable.</p> + +<p>At the third and fourth period in this pulmonary form of the disease, +adopt the treatment prescribed for intestinal typhus.</p> + +<p>We might have greatly enlarged the list of the pharmaceutic agents, but +the richer a treatment is in remedies the poorer it is in cures. We have +made choice of the simplest and safest among all the remedies advised by +experienced men, making allowance for the difficulties inherent to the +number of animals, the mode of application, the cost, &c., always +keeping in view the life of the animal to be saved and the interest of +the cattle owners.</p> + +<p>We think that the treatment by inoculation might have prevented the +typhus in a very large proportion, and that the curative medication +might have saved many of the infected cattle at the worst period of the +epizootia.</p> + +<p>Such, then, are the results which will one day be obtained, when we +shall be able to supersede the barbarous process of general +extermination, by the adoption of a rational treatment, founded at once +on science and practical experience.</p> +<br /> + +<p class="cen"><span class='pagenum'><a name="Page_257" id="Page_257">[Pg 257]</a></span>IV.</p> + +<div class="blockquot"><p class="hang" style="margin-left: 2em;"><i>Hygienic Measures to be taken against the Extension of the +Contagion—Acts and Orders concerning Sanitary Police +Regulations.</i></p></div> + +<p>I have purposely neglected, in discussing the various plans of +treatment, certain measures to be adopted with the object of opposing +the spread of the contagion. The memorandum published on this subject by +the Privy Council, and drawn up by Dr. Thudichum, is so complete and so +clear, that we can find nothing better to say. I recommend its perusal +to all who possess horned cattle, and who have occasion to send them to +any distance. It is of the highest importance to follow this judicious +advice, as the general interest will constitute here the safeguard of +the pecuniary interests of each in particular. I add to this memorandum +upon hygienic measures, the consolidated and amended acts and orders +published under the head of "Sanitary Police." In this way those +interested will have beneath their eyes all which it is important for +them to know, both in a medical and legal point of view.</p> + +<span class='pagenum'><a name="Page_258" id="Page_258">[Pg 258]</a></span> +<div class="blockquot"><p class="hang" style="margin-left: 6em;"><span + class="smcap">Memorandum</span> <i>on the Principles and Practice of Disinfection, as + applicable to the present Epidemic of Cattle Disease</i>. By J. L. W. <span + class="smcap">Thudichum</span>, M.D.</p> +<br /> + +<div class="sidenote">I.—Principles of disinfection.</div> + +<p class="cen">I.—<span class="smcap">Principles of Disinfection.</span></p> + +<div class="sidenote">1. Definition of disinfection.</div> + +<p>1. The term disinfection signifies the removal and destruction, or +destruction and subsequent removal of the products of destruction, of +all matters actually being or containing products of disease capable of +reproducing disease in other animals.</p> + +<div class="sidenote">2. May include special purification and deodorization.</div> + +<p>2. If the same processes and means, as used for this purpose, are +applied to the purification and deodorization of places and things not +actually infected, but capable or suspected of being infected, then +these preventive measures are practically and properly included under +the definition of disinfection.</p> + +<div class="sidenote">3. Reproducers and primary carriers of infection.</div> + +<div class="sidenote">Infectious parts of dead animals.</div> + +<p>3. The reproducers of the infectious matter or contagion are all kinds +of cattle of the ox tribe, which also are at present in this country the +only animals liable to its specific effects. It is probable that the +contagion adheres with particular pertinacity to all secretions and +discharges from sick animals. For this reason, fæces or droppings, +urine, ruminated food, all secretions from the mouth, nose, and eyes, +and any sore parts of the surface of the diseased animals must be +considered as the principal and primary carriers of the infectious +matter or plague poison. It is also probable that many parts of animals +which have died from the cattle plague, or have been killed during +advanced stages of the disease, are infectious, some because they are +primarily imbued with the contagion, others because they have been in +contact with it after the death of the animal. Skins, hides, hair, +horns, <span class='pagenum'><a name="Page_259" id="Page_259">[Pg 259]</a></span>and hoofs, must therefore always be treated with precaution. The +chances of infection by flesh, fat, cleaned guts, and blood, are perhaps +more remote, but cannot be lost sight of.</p> + +<div class="sidenote">4. Particular danger of droppings, or fæces.</div> + +<p>4. The cattle plague, although affecting every part of the animal, shows +its visible effects most extensively in the intestinal canal. It is +believed, and apparently upon good grounds, that the intestinal +discharges are the principal agents, upon the distribution of which +mainly depends the spread of the disorder.</p> + +<div class="sidenote">5. Enumeration of infected things and places.</div> + +<p>5. It follows from the above, that all articles which have been in +contact with a diseased animal, or any of its discharges, particularly +its fæces, are capable of carrying the infection for an indefinite time, +and must be looked upon as being actually infectious to other healthy +animals. Such are racks of wood or iron; cribs or mangers of wood, iron, +or stone; articles used for fastening animals; leather collars and +straps, ropes and chains; all harness of any animals used for drawing, +and all carts, waggons, and carriages which they have actually been +drawing; the stalls or sheds in which animals have been standing; the +whole lengths of the gutters and drains through which their urine has +been flowing; the entire surface over which their manure has been drawn, +and all implements with which the removal has been effected; the entire +dung-heap upon which infected manure has been put, and the fluid +contents of the manure pit, or of the special receptacle for the urine; +yards or sheds in which cattle have been kept to tread down long straw, +and the whole of such straw and manure, as also the ground beneath them; +paths and roads upon which diseased cattle have walked or been carried; +fields and meadows <span class='pagenum'><a name="Page_260" id="Page_260">[Pg 260]</a></span>upon which they have been grazing; all carts, +carriages, trucks and railway trucks in which diseased cattle have been +conveyed, and all the platforms, railings, bridges, and boards upon +which they have been moved thereto; as also all apparatus which has been +used to pen, tie, lift, haul, lower, and fix them; the clothes, and +particularly shoes and boots, and iron-pointed sticks of drivers and +their dogs; the apparel of all cattle-herds or attendants, particularly +their shoes and boots; the shoes and boots of all persons visiting +places where diseased cattle are or have been standing; and, in general, +the clothes of all persons visiting infected places, ships, and all +parts of the platforms, stages, stairs and bridges, hoists and cranes +used for embarking and landing the animals; markets, and all sheds, and +pens, and implements used in contact with cattle; slaughter-houses, and +all persons and implements in them which have been employed upon sick +cattle, as also sundry parts or organs which come from sick animals +killed in slaughter-houses; knackers' yards, trucks or carts, horses, +men, and implements which have been employed in the disposal of sick or +dead animals; wells and ponds from which diseased cattle have been +drinking, or into which any portion of their excreta has had any +opportunity of flowing, directly or indirectly; all fodder, grass, hay, +straw, clover, &c., and particularly remnants of fodder upon which +diseased cattle have been feeding; and, in general, all persons, +animals, places, buildings, and movable things which have been in +contact with matters proceeding from diseased cattle, or with such +diseased cattle themselves. To the above-mentioned places and things any +of the processes and agents <span class='pagenum'><a name="Page_261" id="Page_261">[Pg 261]</a></span>enumerated and described in the following +may have to be applied.</p> +<br /> + +<div class="sidenote">II. Practice of disinfection.</div> + +<p class="cen">II.—<span class="smcap">Practice of Disinfection.</span></p> + +<div class="sidenote">A. Disinfection by earth.<br /> +1. Burying of animals, &c.</div> + +<p>A. <i>Disinfection by Earth.</i> 1. <i>Burying.</i>—All matters that can be +buried, so as to remain covered with a thick layer of ground or earth +are innocuous. The ground chosen for such interment should be dry. The +quickest, and cheapest, and most certain way of disinfecting an animal +dead from the plague is to bury it entire.</p> + +<div class="sidenote">2. Burying of dung.</div> + +<p>2. The droppings, and all straw and other matters contaminated +therewith, may also be buried into ground where they are not likely to +be disturbed for a long time. The places from which such droppings have +been removed to be cleaned and disinfected as will be described below.</p> + +<div class="sidenote">3. Infected manure and compost heaps.</div> + +<p>3. Manure heaps and the down-trodden manure of cattle yards, if they +have become infected by even a small quantity of the droppings of a +diseased animal, should be carefully shifted to a suitable piece of +ground, and there be transformed into compost heaps. A layer of manure +one or two feet in thickness should be covered all over with six inches +of dry earth, ashes, and mineral rubbish; upon this another layer of +manure may be placed, and then again a layer of earth, and so forth, +until the whole of the manure is stacked; it should be covered all over +with a continuous layer of earth of from six inches to one foot in +thickness. If the manure heap or yard manure cannot be shifted, it may +be covered on the spot with a layer of dry earth, after which all +animals are to be kept away from it.</p> +<span class='pagenum'><a name="Page_262" id="Page_262">[Pg 262]</a></span> +<div class="sidenote">4. Removal of boil infected by soakage.</div> + +<p>4. If the floor of any shed or stable in which diseased cattle has been +standing is not constructed with special water-tight and impenetrable +material, it must be assumed to be infected to the depth of at least six +inches. This ground should therefore be removed, together with any +stones, pavements, or wood work which may have been in contact with it, +carted to a piece of dry land and buried. Half-rotten wood is a +particularly favourable carrier of infection. Mortar, bricks, loam, or +any other lining of the sides of a pen in which a diseased animal has +been standing, should be broken out and buried.</p> + +<div class="sidenote">B. Disinfection by fire.</div> + +<div class="sidenote">1. Burning.</div> + +<p>B. <i>Disinfection by Fire.</i> 1. <i>Burning.</i>—All infected articles of a +minor value, or made of incombustible materials, can be disinfected by +exposing them to a heat which will char organic matter. To this class of +articles may be reckoned racks of wood or iron; cribs or mangers of +wood, iron or stone; leather collars and straps, ropes and chains; dry +manure, residues of fodder from which diseased cattle have eaten; and +all such small articles of little value which can easily be replaced by +new ones. Chains may be exposed to a dull red heat; all other articles +may be heated over a fire of coal, brushwood, or straw until well +scorched. All new articles of ironware should be bought in a galvanised +state, to prevent the formation of rust, the accumulations of which form +convenient seats for infectious matter, and for the same purpose it is +desirable that iron articles which have been disinfected by heat as +above should afterwards be either galvanised, or, at least, while hot be +treated with resin, to cover them with a durable varnish, or should be +varnished or painted.</p> +<span class='pagenum'><a name="Page_263" id="Page_263">[Pg 263]</a></span> +<div class="sidenote">C. Disinfection by chloride of lime. General remarks.</div> + +<p>C. <i>Disinfection by Chloride of Lime.</i>—Chloride of lime, or bleaching +powder, is the most powerful, the cheapest and most easily managed of +all artificial disinfectants. It can be had everywhere, and at any time, +and in quantities sufficient for every purpose. It should as much as +possible he applied in solution, of a strength varying somewhat with the +particular purpose for which it is to be employed; and after it has been +allowed to act upon the surface or matter to be disinfected a reasonable +time, should be washed off, together with all products of decomposition. +As chloride of lime does not destroy only the infectious matter in a +mixture, but destroys all organic matter without distinction, it is not +applicable to large quantities of matter, such as the manure of cattle, +dung-heaps, &c., inasmuch as twice or three times the weight of these +matters of chloride of lime would be required for their effectual +destruction and disinfection. It is further inapplicable to all matters +rich in ammonia, particularly putrid urine, as it destroys the ammonia +and evolves a large amount of gases, some of which have a repugnant +odour, and are perhaps not quite innocuous. But for the disinfection of +surfaces of things and places no better or more suitable agent than +chloride of lime is at present known to science.</p> + +<div class="sidenote">D. Special directions for disinfection of stables, sheds, +&c., trucks, and ships, &c.</div> + +<div class="sidenote">1. Special directions.</div> + +<p>D. <i>Special Directions for the Disinfection of Stables, Sheds, Vans, +Railway Trucks, and Cattle Ships,<a name="FNanchor_V_22" id="FNanchor_V_22"></a><a href="#Footnote_V_22" class="fnanchor">[V]</a> and of Persons and Things connected +with them.</i>—1. After such a place has been cleaned by mechanical means, +scraping, &c., as much as possible, and all manure and</p> +<span class='pagenum'><a name="Page_264" id="Page_264">[Pg 264]</a></span> +<div class="sidenote">Washing.</div> + +<div class="sidenote">Scrubbing.</div> + +<div class="sidenote">All washing water to be disinfected.</div> + +<p>dirt has been carefully buried, the entire surface which has been +contaminated, or is likely to have been contaminated, should be covered +with a layer of chloride of lime in powder. The powder should be worked +about with a broom until equally distributed. It is intended to +disinfect the water to be used in the washing process which is now to +commence. Clean water, from a hose in which it flows under pressure, or +from a force-pump, garden-engine, or from large watering-pots or +water-cans, or poured freely from buckets, should now be applied to the +entire surface by one person, while another at the same time scrubs the +entire surface; and particularly all crevices, joints, and +irregularities. The washing water and chloride of lime are then to be +worked down the gutters, into the sinks, cesses, or natural +watercourses. No washing water from any infected place or thing should +ever be allowed to flow into any cesspool, urine-hold, dung-heap, pond, +sewer, or natural watercourse, without having previously been mixed and +stirred with a liberal amount of chloride of lime. When the place has +thus been scrubbed until the water flows off clean, it is ready for +effectual disinfection.</p> + +<div class="sidenote">2. Actual disinfection.</div> + +<div class="sidenote">Solution of chloride of lime.</div> + +<div class="sidenote">How applied.</div> + +<div class="sidenote">How long to be left on.</div> + +<p>2. For this purpose a solution of chloride of lime in water, in the +proportion of one pound of the powder to one gallon of water, is made. +For the lair of one animal from six to ten gallons of such fluid should +be prepared. This fluid is now distributed over the whole surface to be +disinfected, gradually, by squirting from a syringe, or by pumping +through a force-pump, garden-engine, or by watering from a watering-pot +or can with a finely pierced rose. All woodwork, stones, bricks, cement, +mortar, all fixtures of whatever material, <span class='pagenum'><a name="Page_265" id="Page_265">[Pg 265]</a></span>should be well wetted with +the solution, and immediately be scrubbed with a hard brush. Floor and +ceiling are also scrubbed, and the whole is left in this wet state +covered with the chloride of lime solution for at least one hour, during +which time care is taken that no parts become dry.</p> + +<div class="sidenote">3. To be washed off after disinfection.</div> + +<div class="sidenote">Flushing.</div> + +<div class="sidenote">Precautions as to direction of clean water.</div> + +<p>3. As the chloride of lime and the products of its decomposing action +upon infectious matters may be hurtful to cattle, these matters have to +be carefully washed off by a second and final flushing. For this too +much water and too much scrubbing cannot be employed. Care should be +taken to apply the clean water always to the highest parts, so as to +cause it to flow thence to the lower parts, and to wash away the waste +from the lower parts before applying any fresh water to the upper parts.</p> + +<div class="sidenote">4. Care not to carry back dirt by brooms, boots, &c.</div> + +<p>4. Care should also be taken to rinse and flush every broom which has +worked away sediment and waste from the lower parts into and through the +gutters and drains before applying it again to the clean upper parts. +Care should also be taken that the working persons should not step from +the dirty or partially cleansed places on to the clean ones, as this may +suffice to bring infection back to the disinfected place.</p> + +<div class="sidenote">5. Disinfection of workmen and tools.</div> + +<p>5. Lastly, all persons employed in this work, having swept and flushed +the gutters with the same care as the lairs, are collected, together +with all engines and tools which they have used, as near as possible to +the sink or place of final egress of water from the premises, and there +disinfected as will be described.</p> + +<div class="sidenote">Tools.</div> + +<p>The tools, such as hooks, forks, spades, hoes, barrows, &c., are +scrubbed with the above solution of chloride of lime, and subsequently +water until clean; they are <span class='pagenum'><a name="Page_266" id="Page_266">[Pg 266]</a></span>then repeatedly wetted with the solution, +and after it has had time to disinfect the entire surfaces of them, they +are washed clean and laid up, or hung up to dry.</p> + +<div class="sidenote">Workmen.</div> + +<div class="sidenote">Disinfection of boots.</div> + +<div class="sidenote">Disinfection of workpeople's bodies, hands, &c.</div> + +<div class="sidenote">Changing and disinfecting clothes.</div> + +<div class="sidenote">Burning of articles of little value.</div> + +<p>The workmen, then, having finished the disinfection and flushing of all +objects and surfaces, effect their own disinfection in the following +manner:—They wash their boots most carefully with chloride of lime and +water, scraping the soles and scrubbing the seams where the soles join +the upper leather. They wash their hands and arms, and by means of clean +rags or sponges they remove any splashes from their clothes. After this +they go indoors, remove all clothes from head to foot, wash their +bodies, and particularly their hands, faces, hair and feet, with plenty +of soap and water, and put on fresh clothes and linen. The clothes and +linen which they have taken off should be treated as infected, set to +soak immediately in boiling water and afterwards disinfected, or in +water containing two ounces of chloride of lime to the gallon in +solution, or containing four ounces of Condy's red permanganate of +potash fluid in solution; or the clothes and linen should be put in a +copper and boiled and subsequently washed. All articles of little value +which are much soiled should be burned on a bright fire.</p> + +<div class="sidenote">E. Disinfection of live stock.</div> + +<div class="sidenote">1. Stock may carry infection in two modes.</div> + +<p>E. <i>Disinfection of Live Stock.</i>—1. Live cattle may carry infection in +two ways: first, by being themselves infected with the plague and +reproducing the poison; and secondly, by accidentally carrying the +poison from other animals in a dormant state upon some part of their +surface, their hair, and particularly their feet. These latter animals +may therefore infect others without being or becoming themselves +subjects of the <span class='pagenum'><a name="Page_267" id="Page_267">[Pg 267]</a></span>plague. All persons therefore buying new animals, +should disinfect them before allowing them to enter their premises. In a +similar manner, if in a stable there has been a case of plague, the +healthy or apparently healthy animals should all be disinfected.</p> + +<div class="sidenote">2. Mode and means of disinfecting live stock.</div> + +<div class="sidenote">Warming and refreshing drink.</div> + +<div class="sidenote">Penned in the quarantine shed.</div> + +<p>2. The mode in which live animals may be disinfected, consists in +washing them with disinfectant solutions of such strength as will +destroy the contagion without injuring the surface of the animal. A +solution of two ounces of chloride of lime in a gallon of water, is a +proper solution for washing the coat of animals. A mixture of four +ounces of Condy's red permanganate of potash fluid, with one gallon of +water, is also a proper disinfectant solution. For full-sized cows and +bullocks, &c., several gallons of either of these solutions should be +used. Great care should be taken to keep the solution away from the +eyes, nostrils, mouth, and tender parts. When the entire surface is +washed and disinfected, all disinfectant is removed by the application +of great quantities of clean tepid water to all parts. The animal is +given a warming and refreshing drink, and is conducted by a clean +attendant to the clean quarantine shed. There it should receive fodder +both dry and green, and sop, and plenty of pure cold water, and be +rubbed dry with whisks of straw and hay.</p> + +<div class="sidenote">F. The quarantine shed.</div> + +<div class="sidenote">1. Objects.</div> + +<div class="sidenote">Both quarantine and surface disinfection are required.</div> + +<p>F. <i>The Quarantine Shed.</i>—1. The quarantine shed is intended to keep +the new and suspected cattle separate for a period of at least ten days, +in order to afford the security, to be obtained by observation alone, +that it is not actually infected with plague. While, therefore, +disinfection of the surface of cattle removes one +<span class='pagenum'><a name="Page_268" id="Page_268">[Pg 268]</a></span>kind of danger, another, which cannot be removed, can only be kept +circumscribed or penned in, and this is done by the quarantine shed. But +the keeping of cattle in the quarantine shed would not disinfect its +surface with certainty even during a much longer period than ten days; +disinfection of the surface therefore cannot supply the precaution of +the quarantine shed, and a rigorous quarantine cannot supply the effect +of surface disinfection. Both precautions are necessary for perfect +security, although either of them, without the other, obviates a +particular kind and a certain amount of danger.</p> + +<div class="sidenote">2. Management of the quarantine shed.</div> + +<p>2. The quarantine shed should be situated in an isolated part of the +premises. All manure and urine from it should flow and be carried to a +particular place separate and distinct from the common dung-heap, and be +buried daily.</p> + +<div class="sidenote">Cleanliness.</div> + +<div class="sidenote">Persons attending healthy stock not to attend quarantine +shed, and vice versâ.</div> + +<p>The utmost cleanliness should be observed in the shed. All tools, pails, +currycombs, etc., used in this shed should be used in it exclusively and +nowhere else. The person attending the quarantine shed should not be +allowed to go into the shed where healthy stock is kept, or permitted to +approach healthy stock. No person attending healthy stock should be +permitted to approach quarantine cattle, or to go near or into the +quarantine shed. But should unfortunately only one person be available +for both duties, that person should be allowed to approach quarantine +cattle only when clothed in the safety dress to be immediately +described.</p> + +<div class="sidenote">G. The safety dress.<br /> +1. Description.</div> + +<p>G. <i>The Safety Dress.</i>—1. This consists of strong water-boots reaching +up to the knees, well greased all over; of a waterproof coat, buttoned +close all the way <span class='pagenum'><a name="Page_269" id="Page_269">[Pg 269]</a></span>up in front, and closing tightly round the neck and +wrists. The head is to be covered with a cap which takes the hair well +in.</p> + +<div class="sidenote">2. Persons who should use the safety dress.</div> + +<div class="sidenote">To disinfect before leaving suspected or infected premises.</div> + +<p>2. Every person having occasion to visit sheds in which there is +diseased cattle, or suspected cattle, or quarantine cattle, should be +provided with the above dress, put it on when entering the place, take +it off when leaving the place, and have it disinfected immediately. This +precaution should be strictly observed by all inspectors, all +veterinarians, or others called in to attend sick cattle, by all dealers +and butchers entering sheds, yards, or meadows, for the purpose of sale +or purchase, and by all other persons coming on the premises on business +in connexion with cattle.</p> + +<div class="sidenote">3. Strangers not to enter sheds except in disinfected safety +dresses.</div> + +<div class="sidenote">Proprietors of cattle to keep safety dresses.</div> + +<p>3. The owners of stock should not allow any strangers to enter their +sheds, yards, or meadows, except in disinfected safety-dresses; and in +case this should give rise to difficulties, they will do well to have +themselves one or two such safety-dresses at hand, and to cause all +persons whose business compels them to enter their sheds, to leave their +own boots behind, and to put on the long boots, waterproof-coat, and +special cap. Only thus can they hope to exclude all ordinary and obvious +chances of infection from their previously healthy sheds, yards, and +meadows.</p> + +<div class="sidenote">H. Measures to be taken where plague has appeared.</div> + +<div class="sidenote">Killing and burying diseased animals.</div> + +<div class="sidenote">Disinfecting the living and the stables.</div> + +<p>H. <i>Measures to be taken on Premises where Plague has actually +appeared.</i>—1. When the plague has actually appeared in any shed, yard, +or place, the sick animal should at once be removed with all due +precautions. It is certainly the safest and best to pole-axe the animal +at once, and to bury it entire, and then to disinfect the particular +lair as above described, clear <span class='pagenum'><a name="Page_270" id="Page_270">[Pg 270]</a></span>out the stable or shed, disinfect the +whole of it and all apparatus, also all the animals, and only to let the +animals enter the shed, &c. again, after it is completely sweet and dry.</p> + +<div class="sidenote">2. Hospital shed.</div> + +<div class="sidenote">Situation of.</div> + +<p>2. If, however, a proprietor is desirous of keeping a sick animal +because its illness does not appear severe or fatal, he should place it +in a separate shed, which must not be the same as or near to the +quarantine shed, and be distant from all healthy animals, and so +situated that the prevailing wind does not blow from this hospital shed +towards the healthy or quarantine shed. The water should also not flow +from this hospital shed towards the others, or the yard, or any meadow, +but should be carefully drained away and sent off the premises by a +special sink.</p> + +<div class="sidenote">3. Preventing of diffusion of fæces.</div> + +<p>3. To prevent the scattering of fæces by infected animals (and also by +suspected animals and all animals suffering from diarrhœa), their +tails should be so tied to one or other of their horns as to protect +them against being soiled by the intestinal discharges, and to prevent +them from distributing such discharges by the ceaseless motions peculiar +to these organs. The spattering of fæces should be prevented by a +copious supply of rough straw, with some sand, sawdust, or ashes placed +behind and underneath the animal. The straw and fæces should be dealt +with as has been described. Animals affected with plague or diarrhœa +should not be led along streets, highroads, and paths, as they would be +certain to drop infectious fæces, which would then be distributed over +the entire length of these roads by the feet of men and animals, and the +wheels of vehicles.</p> + +<div class="sidenote"><span class='pagenum'><a name="Page_271" id="Page_271">[Pg 271]</a></span>4. Special management of hospital shed.</div> + +<div class="sidenote">Persons to be employed.</div> + +<p>4. The sick animals should be disinfected repeatedly; their pens should +be cleaned and disinfected repeatedly, during the course of the illness. +This should be done by persons either guarded by the safety dress, +or—and this is safest—by such as may not come into contact with +healthy cattle, or have to enter healthy sheds. All tools, pails, +fodder, &c., to be used in the hospital shed to be kept for that purpose +only, and never to be used with healthy, or quarantine, or only +suspected cattle.</p> + +<div class="sidenote">5. Disinfection of parts of dead or killed animals.</div> + +<p>5. If the proprietor of any dead piece of cattle, whether it has died +naturally or been killed, should decide upon dismembering it instead of +burying it entire, and upon utilising the hide, horns, hoofs, tallow, +and bones, he should disinfect the skin, horns, and hoofs, by steeping +them for one hour in a strong solution of chloride of lime, containing +one pound of the powder in each gallon of water, and afterwards washing +them. The tallow should be thickly powdered with chloride of lime all +over, and be sent directly to the boilers. It should not be boiled in +any vessel employed on the farm. Under all circumstances, it is +advisable to let this dismemberment of dead and fallen cattle he +performed at the knacker's yard.</p> + +<div class="sidenote">6. Flesh, &c., to be buried.</div> + +<p>6. Flesh, blood, guts, lungs, and the bones of the head of infected +animals should not be trafficked with, as they cannot easily be +disinfected. They should always be buried.</p> + +<div class="sidenote">I. Disinfection of meadows, fields, roads, &c.</div> + +<div class="sidenote">1. Meadows.</div> + +<p>I. <i>Disinfection of Meadows, Fields, Roads, &c.</i>—1. Meadows infected by +diseased cattle should be carefully cleaned of all dung, by burying each +dropping on the spot where it lies, cutting out the round piece of <span class='pagenum'><a name="Page_272" id="Page_272">[Pg 272]</a></span>turf +with the dropping on it, and turning it upside down. The grass on the +entire meadow should then be cut and burned. It should then be left +without any cattle for at least a month, including at least two wet +days.</p> + +<div class="sidenote">2. Of roads, &c.</div> + +<p>2. All roads, paths, streets of towns, or villages should be carefully +and frequently scavenged. All carts, vans, or waggons used for carrying +manure, should be water-tight, caulked and painted, and should not be +permitted to ooze and drop their fluid or semi-fluid contents on the +road over which they are drawn. They should be kept clean and +disinfected, as a precautionary measure, by the proceedings above +described.</p> +<br /> + +<div class="sidenote">III. General recommendations.</div> + +<p class="cen">III. <span class="smcap">General Recommendations.</span></p> + +<p>In conclusion it must be pointed out to farmers, dairymen, and all +persons having charge of cattle,</p> + +<div class="blockquot"><p class="hang" style="margin-left: 2em;"><i>That the same great measures which are known to maintain and +restore the health of human beings, will also maintain and +restore the health of cattle.</i></p></div> + +<p>Pure air; dry, spacious, well-ventilated and well-drained clean sheds; +clean and dry meadows; plenty of pure water; frequent currying and +washing; the prevention of the development, by the destruction of the +germs, of internal and external parasites, particularly entozoa; proper +food in suitable quantities, and at proper times; protection from +inclement weather; the utmost cleanliness in the removal of manure; the +storing of the manure at a great distance from the cattle-shed, and, in +addition, the most conscientious observance of the precautionary and +disinfecting measures above described—all these measures and agents +<span class='pagenum'><a name="Page_273" id="Page_273">[Pg 273]</a></span>together will secure the utmost possible health of stock and the +prosperity of the agriculturist and dairyman. But the neglect of any one +of them will make the stock liable to become infected, and the more so +the more several or all collateral conditions of the healthy existence +of animals are neglected. The negligent man is therefore certain to +lose, to injure his neighbour by defeating his precautions, and to +damage society; but the watchful and painstaking man will be rewarded +not only by the preservation of his property, but particularly by the +consciousness that it has been preserved by his own care and attention, +and that thereby he has also benefited the state.</p> +</div> + +<hr /> + +<p>This consolidates and amends the former Orders.</p> + +<div class="blockquot"><p class="cen">(<i>Copy.</i>)</p> + +<p>At the <i>Council Chamber, Whitehall</i>, the 22nd day of +<i>September</i>, 1865.</p> + +<p class="cen">By the Lords of Her Majesty's Most Honourable Privy Council.</p> + +<div style="margin-left: 35%; margin-right: 20%;"> +<span class="smcap"> Present.</span><br /> +Lord President.<br /> +Duke of Somerset.<br /> +Earl of Clarendon.<br /> +Earl de Grey and Ripon.<br /> +Mr. Secretary Cardwell.<br /> +Mr. H. A. Bruce.</div> + + +<p><span class="smcap">Whereas</span> by an Act passed in the session of the eleventh and +twelfth years of Her present Majesty's <span class='pagenum'><a name="Page_274" id="Page_274">[Pg 274]</a></span>reign, chapter one hundred and +seven, intituled "An Act to prevent until the 1st day of September, +1850, and to the end of the then next session of Parliament, the +spreading of contagious or infectious disorders amongst sheep, cattle, +and other animals," and which has since been from time to time continued +by divers subsequent Acts, and lastly by an Act passed in the session of +the twenty-eighth and twenty-ninth years of the reign of Her present +Majesty, chapter one hundred and nineteen, it is (amongst other things) +enacted that it shall be lawful for the Lords and others of Her +Majesty's Privy Council, or any two or more of them, from time to time, +to make such Orders and Regulations as to them may seem necessary for +the purpose of prohibiting or regulating the removal to or from such +parts or places as they may designate in such Order or Orders, of sheep, +cattle, horses, swine, or other animals, or of meat, skins, hides, +horns, hoofs, or other part of any animals, or of hay, straw, fodder, or +other articles likely to propagate infection; and also for the purpose +of purifying any yard, stable, outhouse, or other place, or any waggons, +carts, carriages, or other vehicles; and also for the purpose of +directing how any animals dying in a diseased state, or any animals, +parts of animals, or other things seized under the provisions of the +said Act, are to be disposed of; and also for the purpose of causing +notices to be given of the appearance of any disorder among sheep, +cattle, or other animals, and to make any other Orders or Regulations +for the purpose of giving effect to the provisions of the said Act, and +again to revoke, alter, or vary any such Orders or Regulations; and that +all provisions for any of the purposes aforesaid in any such Order or +Orders contained shall have the like force and <span class='pagenum'><a name="Page_275" id="Page_275">[Pg 275]</a></span>effect as if the same +had been inserted in the said Act; and that all persons offending +against the said Act shall for each and every offence forfeit and pay +any sum not exceeding twenty pounds, or such smaller sum as the said +Lords or others of Her Majesty's Privy Council may in any case by such +Order direct:—</p> + +<p>And whereas a contagious or infectious disorder now prevails among the +cattle of Great Britain, which is generally designated the "cattle +plague," and may be recognised by the following symptoms:—</p> + +<p>"Great depression of the vital powers, frequent shivering, staggering +gait, cold extremities, quick and short breathing, drooping head, +reddened eyes, with a discharge from them, and also from the nostrils, +of a mucous nature; raw-looking places on the inner side of the lips and +roof of the mouth, diarrhœa or dysenteric purging:"</p> + +<p>And whereas several Orders, dated respectively the 24th of July, the +11th, 18th, and 26th of August, 1865, have been made under the authority +of the said Acts by the Lords of Her Majesty's Privy Council, with a +view to check the spreading of the said disorder:</p> + +<p>And whereas it is expedient to consolidate and amend the said Orders:</p> + +<p>Now, therefore, the Lords of Her Majesty's Privy Council do hereby, by +virtue of, and in exercise of the powers given by, the said Act, so +continued as aforesaid, order as follows:—</p> + +<p>1. This Order shall extend to all parts of Great Britain.</p> + +<p>2. The said Orders dated respectively the 24th of July, the 11th, 18th, +and 26th of August, 1865, are revoked, with the exception of so much of +the said Order <span class='pagenum'><a name="Page_276" id="Page_276">[Pg 276]</a></span>of the 24th of July, 1865, as empowers the Clerk of Her +Majesty's Privy Council to appoint Inspectors within the limits of the +Metropolitan Police District, provided that such revocation shall not +affect any appointment made, or any act done, or penalty recoverable, +under any Order hereby revoked.</p> + +<p>3. In this Order the word "animal" shall mean any cow, heifer, bull, +bullock, ox, calf, sheep, lamb, goat, or swine; and the word "Inspector" +shall include any Inspector appointed under this Order, or under any of +the said revoked Orders.</p> + +<p>4. Whenever the Local Authority, as hereinafter defined, shall be +satisfied of the existence of the said disorder in, or have reason to +apprehend its approach to, the district over which his or their +jurisdiction extends, it shall be lawful for such Local Authority, if he +or they shall think fit, from time to time to appoint one or more +Veterinary Surgeon or Surgeons, or other duly qualified person or +persons, to be an Inspector or Inspectors, for the purpose of carrying +into effect the rules and regulations made by this Order, within the +district for which he or they shall have been appointed. And the same +authority may, from time to time, revoke such appointment.</p> + +<p>5. Subject to the powers herein reserved to the Clerk of Her Majesty's +Privy Council, the Local Authority within the City of London, and the +liberties thereof, shall be the Lord Mayor; in any municipal borough in +England or Wales, the Mayor; in any Petty Sessional Division in England +or Wales (exclusive so far as relates to the jurisdiction of the +Inspector of so much of the said division as lies, within the limits of +a municipal borough for which an Inspector has been appointed), <span class='pagenum'><a name="Page_277" id="Page_277">[Pg 277]</a></span>the +Justices acting in and for such Petty Sessional Division. The Local +Authority in any burgh or town in Scotland which is subject to the +jurisdiction of a Provost or other Principal Magistrate, shall be the +Provost or such Principal Magistrate; and in any other place in Scotland +not within the jurisdiction of such Provost or other Principal +Magistrate, the Justices of the County in Sessions assembled.</p> + +<p>6. Every Inspector shall from time to time report to the Local Authority +by which he is appointed, the steps taken by him for carrying into +effect the regulations prescribed by this Order; and the Local Authority +shall certify, in such manner as may be directed by one of Her Majesty's +Principal Secretaries of State, the number of days that such Inspector +has actually been engaged in the performance of his duty, and the number +of miles travelled by him while thus engaged.</p> + +<p>7. Every Inspector shall furnish the Lords of the Council with such +information in regard to the said disorder, as their Lordships may, from +time to time, require.</p> + +<p>8. Every person having in his possession, or under his custody, any +animal labouring under the said disorder, shall forthwith give notice +thereof to the Inspector of the district within which such person +resides, or if no Inspector shall have been appointed for the district +within which such person resides, then to the Officers hereinafter +named, according to the place of residence of the person obliged to give +notice; that is to say: within the Metropolitan Police District, to the +said Clerk of the Privy Council; within the City of London, and the +liberties thereof, to the Lord Mayor; within any other borough, burgh, +or town subject to the jurisdiction of a <span class='pagenum'><a name="Page_278" id="Page_278">[Pg 278]</a></span>Mayor, Provost, or other +Principal Magistrate, to such Mayor, Provost, or other Principal +Magistrate; elsewhere in England, to the Clerk of the Justices acting in +and for the Petty Sessional Division; and elsewhere in Scotland, to the +Clerk of the Peace of the county.</p> + +<p>9. Every Inspector shalt have power to enter upon and inspect any +premises or place in which any animal or animals may be found within the +district for which he is appointed, and to examine and inspect, whenever +and wherever he may deem it necessary, any animal within such district.</p> + +<p>10. Every Inspector shall have power within his district to seize and +slaughter, or cause to be seized and slaughtered, and to be buried, as +hereinafter directed, in any convenient place, any animal labouring +under the said disorder.</p> + +<p>11. Every Inspector shall have power within his district to cause to be +cleansed and disinfected, in any manner which he may think proper, any +premises in which animals labouring under the said disorder have been, +or may be, and to cause to be disinfected, and if necessary destroyed, +any fodder, manure, or refuse matter, which he may deem likely to +propagate the said disorder. And every owner or occupier of such +premises shall obey any order given by such Inspector for that purpose.</p> + +<p>12. Every Inspector shall have power within his district to direct that +any animal which he suspects to be labouring under the said disorder, +shall be kept separate from animals free from the said disorder. And +every person having in his possession, or under his custody, such +animal, shall obey any order given by such Inspector for that purpose.</p> + +<p>13. Every person having in his possession, or under <span class='pagenum'><a name="Page_279" id="Page_279">[Pg 279]</a></span>his custody, any +animal labouring under the said disorder, shall, as far as practicable, +keep such animal separate from all other animals, and shall not, if the +animal be within a district for which an Inspector has been appointed, +remove the same from his land or premises, without the licence of the +Inspector.</p> + +<p>14. No person shall send or bring to any fair or market, or expose for +sale, or send or carry by any railway, or by any ship or vessel +coastwise, or place upon, or drive along, any highway or the sides +thereof; any animal labouring under the said disorder.</p> + +<p>15. No person in any district for which an Inspector has been appointed +shall, without the licence of the Inspector, send or bring to or from +market, or remove from his land or premises, any animal which has been +in the same shed or stable, or has been in the same herd or flock, or +has been in contact, with any animal labouring under the said disorder.</p> + +<p>16. No person shall place, or keep, any animal labouring under the said +disorder in any common or unenclosed land, or, if the animal be in a +district for which an Inspector has been appointed, in any field or +pasture, where, in the judgment of the Inspector, such animal may be +likely to propagate the said disorder.</p> + +<p>17. All animals having died of the said disorder, or having been +slaughtered on account thereof; shall be buried with their skins, and +with a sufficient quantity of quick-lime, or other disinfectant, as soon +as practicable, and shall be covered with at least five feet of earth, +or shall, in districts for which an Inspector has been appointed, with +the consent of the owner, be otherwise disposed of; in manner directed +by the Inspector.</p> + +<p>18. During the continuance of the "cattle plague" <span class='pagenum'><a name="Page_280" id="Page_280">[Pg 280]</a></span>within the said City +of London, or that part of the Metropolitan Police District which is +under the jurisdiction of the Metropolitan Board of Works, no animal +shall be brought or sent to the Metropolitan Cattle Market, or any other +market within the said City or the said part of the Metropolitan Police +District, except for the purpose of being there sold for immediate +slaughtering; and every such animal, as soon as sold, shall be marked +for slaughter, in the manner in which cattle are ordinarily marked for +slaughter in the Metropolitan Cattle Market.</p> + +<p>19. Whenever any Local Authority, as hereinbefore defined, declares, by +notice published in any newspaper circulating within his or their +jurisdiction, that it is expedient that animals, as hereinbefore +defined, or some specified description thereof, shall be excluded from +any specified market or fair within that jurisdiction, for a time to be +specified in such notice, it is hereby ordered, that after the +publication of such notice, it shall not be lawful for any person to +bring or send such animals or description thereof into such market or +fair: provided always, that this clause of this Order shall not, unless +renewed by a further Order, be in force after the expiration of three +calendar months from the date of this Order.</p> + +<p>20. Every person offending against this Order shall, in pursuance of the +said Act, for every such offence forfeit any sum not exceeding twenty +pounds which the Justices before whom he or she shall be convicted of +such offence may think fit to impose.</p> + +<p class="right"> +(Signed) <span class="smcap">Arthur Helps</span>.</p> +</div> + +<h4>FOOTNOTES:</h4> + +<div class="footnote"><p class="noin"><a name="Footnote_R_18" id="Footnote_R_18"></a><a href="#FNanchor_R_18"><span class="label">[R]</span></a> Since these lines were put into the printer's hands, the +French Government have proposed to other nations to take measures +collectively to prevent the pilgrimage to Mecca continuing to be a cause +of the spread of cholera. We hasten to render justice to this prudent +initiative. But why not take the same measures against typhus which are +judged necessary against cholera?</p></div> + +<div class="footnote"><p class="noin"><a name="Footnote_S_19" id="Footnote_S_19"></a><a href="#FNanchor_S_19"><span class="label">[S]</span></a> The typhus which broke out fifteen days ago near Roubaix, +in France, bordering upon Belgium, where the epizootia rages, appears to +have been stifled in its focus by the instantaneous extermination of the +whole herd in which it declared itself.</p></div> + +<div class="footnote"><p class="noin"><a name="Footnote_T_20" id="Footnote_T_20"></a><a href="#FNanchor_T_20"><span class="label">[T]</span></a> "It is amusing to read authors of the last century on the +treatment of this disease. They were far more confident in their powers +than we helpless creatures pretend to be. The directions given are full +and distinct, and in chapters boldly headed 'The Cure.' The beast is to +be bled, washed, and hot vinegar and water, with aromatic herbs, may be +placed in the stable to revive the cattle. The animal must be rubbed a +quarter of an hour, both morning and evening, and the bags of a milch +cow should be anointed morning and evening with warm oil. A rowel is to +be made in the dewlap by taking a skein of hemp, tow, or twisted +packthread, a foot long, and as thick as a man's thumb. <i>The +prescriptions are most amusing.</i> They may serve to entertain those who +want the cure at present, and for this reason I reproduce one or +two."—<i>Gamgee, Letter on 21st August.</i></p></div> + +<div class="footnote"><p class="noin"><a name="Footnote_U_21" id="Footnote_U_21"></a><a href="#FNanchor_U_21"><span class="label">[U]</span></a> Dr. Letheby reported that 12,916 lbs., or more than five +tons of meat, had been condemned in the City markets during the past +week as unfit for human food. It consisted of 64 sheep, 4 calves, 7 +pigs, 142 quarters of beef, and 361 joints and pieces of meat; 5377 lbs. +were diseased or from animals that had died of disease, and the rest was +putrid. All of it was destroyed. Yesterday, a sub-committee of the +Metropolitan Plague Committee, at a meeting at the Mansion House, passed +an unanimous resolution, on the motion of Mr. Brewster, recommending +that, as unexpected and insuperable difficulties had arisen in carrying +out the purposes for which they were appointed, the money already +subscribed should be returned to the subscribers, after deducting, <i>pro +ratâ</i>, the expenses already incurred.</p></div> + +<div class="footnote"><p class="noin"><a name="Footnote_V_22" id="Footnote_V_22"></a><a href="#FNanchor_V_22"><span class="label">[V]</span></a> For the disinfection of railway trucks and cattle ships, +see Special Memorandum.</p></div> +<br /> +<br /> +<br /><span class='pagenum'><a name="Page_281" id="Page_281">[Pg 281]</a></span> +<br /> + +<hr /> +<br /> +<h2>THIRD PART.</h2> + +<p class="cen"><i>To Farmers and Graziers.</i></p> +<br /> + +<p>You would have had just cause to reproach me with a want of common sense +if I had obliged you to read a book of two hundred pages, and to lose +your time in looking for the advice you will require, if the cattle +plague should visit your stalls and herds, instead of being able to turn +at once to the matter which concerns you. I have taken up my pen on +purpose to be of service to you; this is my principal duty, which I am +now going to fulfil by summing up in a few pages the most important +facts which have been described in the two first parts of this work.</p> + +<p>The cattle plague, which has lately fallen upon horned beasts, is a +plague, no doubt: but there are different species of plagues, and it is +necessary that you should know that this <span class='pagenum'><a name="Page_282" id="Page_282">[Pg 282]</a></span>disease is one arising from +the absorption of seeds and germs with which the air is impregnated, and +which is drawn by the animals into their bodies when breathing the air +around them. When these germs, these infectious poisons, have penetrated +into the lungs and blood of the animals, these seeds of infection remain +there from eight to twelve days without producing any very perceptible +effects; but after that time the tainted animal becomes dejected, loses +his appetite, is seized with fever, laborious breathing, and +diarrhœa, to which sum of disorders in the health of oxen, cows, &c., +the name of <i>typhus</i> has been given; or, as this distemper is contagious +in the highest degree, it has also been called the <i>contagious typhus</i>.</p> + +<p>You may compare this disease, in order to form a more precise idea of +it, to the small-pox, which sometimes afflicts your children, or to +typhoid fever. These complaints, which are familiar to most of you, have +some resemblance to the typhus of the ox. Only in the small-pox, which +is caught by contagion, and which seldom attacks more than once, like +typhus, the disease is localized <span class='pagenum'><a name="Page_283" id="Page_283">[Pg 283]</a></span>on the skin; whilst in the cattle +plague the internal organs are the principal seat of the evil.</p> + +<p>This comparison will show you at once that the cattle plague, or rather +the cattle typhus, can only be cured when the disease has run its full +course, as you have observed in a person tainted with small-pox; so that +your task must be to help the sick animal to endure his complaint until +the end, or until he is cured; and you must not attempt to check it by +violent means, for if you did you would hasten the death which you +desire to prevent. You will likewise understand that if the disease—as +is certainly the case—does not attack the same animal twice, it would +be very beneficial to inoculate the animal whilst he is sound and +healthy, whenever this scourge threatens—as in the present time—to +attack all cattle. Perhaps you may be told that inoculation, which +prevents small-pox in man, cannot be applicable to cattle; that animals +inoculated with the virus of the typhus have all died of the +consequences of the operation, and so on. To all these objections you +will answer, with that downright good sense which belongs to your class, +<i>that Nature cannot have <span class='pagenum'><a name="Page_284" id="Page_284">[Pg 284]</a></span>two weights and two measures</i>; and that if the +inoculation of the typhus kills animals, whilst the inoculation of the +small-pox saves men, both maladies being governed by the same laws, it +is the inexperience of physicians, and not the operation itself, which +must be made to account for it.</p> + +<p>In a word, to sow virus is to reap it; but there are many ways of sowing +it, and one man will reap a rich harvest, whilst another shall gather +nothing but tares. Let those unbelievers say what they like, and take my +word for it, that we shall one day cure typhus as frequently as we do +small-pox, by inoculating it, and when it appears in spite of that +course, by treating it medicinally.</p> + +<p>This contagious disease is very frequent in certain countries, +principally in Russia and Hungary, on the banks of the great rivers +which empty themselves into the Black Sea. In those remote countries, +when the seasons are either too rainy or too hot—and you know what a +summer that of 1865 has been—the pastures generate the pestilential +poisons of the typhus, the cattle absorb these destructive principles, +and die of them.</p> + +<p><span class='pagenum'><a name="Page_285" id="Page_285">[Pg 285]</a></span>But as the herds of cattle in those countries are bred for sale, and are +sent for that purpose to other countries, to France, Italy, England, +&c., the animals which have had the germ of the disease transport it +with them wherever they go. Thus, it is certain that some oxen conveyed +from Russia and Hungary, where the typhus frequently rages, brought the +disease with them into Great Britain in the month of last June; and as +the complaint is communicated from one animal to another, and afterwards +at great distances, it spread with great rapidity over England and +Scotland. So great are its powers of contagion, that some of the cattle +sent back from England have transmitted the disease to Holland, in the +first place, and afterwards to Belgium; and it was feared at one time +that all Europe would be invaded by it.</p> + +<p>The first belief was—and everything tends to make good the +opinion—that the typhus originally came from abroad; but many +respectable authorities, seeing the foul and nauseous state of the +stalls and cowsheds both in London and elsewhere, the overcrowding of +the animals, and the general neglect to <span class='pagenum'><a name="Page_286" id="Page_286">[Pg 286]</a></span>which they are exposed, have +asserted that the disease had its origin in London. This, we repeat, is +not likely to have been the case, but it is not absolutely impossible; +at all events, there can be no question that the grievous conditions in +which some of your brethren keep their cattle have contributed to spread +the distemper, independently of other causes.</p> + +<p>Moreover, it is necessary to tell you, that sheep and horned cattle are +of all living animals those which are most sensitive to the influence of +contagious diseases. Every year you see instances of this fact in your +own fields and meadows. Your sheep, you all know, easily contract the +small-pox, worm diseases both on the skin and in the interior of the +body; your oxen have aphthous diseases, disorders of the blood and the +lungs, scabs and carbuncles—diseases which are all more or less +contagious, and which are generally brought on by want of care, and, +above all, by improper feeding: by which you see how much of the +sufferings of the cattle, and of the heavy losses to you which follow +them, depends upon yourselves and may be <span class='pagenum'><a name="Page_287" id="Page_287">[Pg 287]</a></span>avoided. Besides, these poor +creatures, which some of you treat so harshly, are extremely +susceptible, and the blows they receive may easily affect their whole +mass of blood. You must, therefore, for your own sakes, treat them more +kindly and gently.</p> + +<p>Therefore, the typhus which was imported from Russia into England, +finding your cattle in such wretched conditions of cleanliness and +health, was propagated amongst them with fearful rapidity. When once the +disease had developed itself within your sheds and stalls, it would have +been the wisest plan immediately to kill the sick cattle, or to treat +them medicinally, carefully abstaining from driving to market any of +your beasts which had been exposed to the contagion. But unfortunately +you did not act in this manner; many amongst you could not put up +patiently with your losses, and only consulting your private interest, +to the detriment of the general good, you sold your sick cows and oxen, +and sowing the contagion about the country and through the markets, the +scourge was soon scattered in every direction, so that instead of +stifling the disease at its birth <span class='pagenum'><a name="Page_288" id="Page_288">[Pg 288]</a></span>everything was done to propagate and +diffuse it.</p> + +<p>Now, if we add, that the germs of this typhus penetrate everywhere, that +it is sufficient to convey sick cattle along the public roads, and by +this means to pass near farms and meadows containing healthy cattle, to +transmit the contagion, that these noxious germs impregnate your own +clothes, the fleece of sheep, and every article, implement, and vehicle +used in agriculture, you cannot but see how often, though unwillingly, +you must have disseminated the evil far and wide.</p> + +<p>The germs, the miasmata of the disease, insinuate themselves not only +upon animals and men, but they shed their virus upon the grass of the +fields, the walls of the stalls and stables, and every agricultural +utensil. Every tainted animal scatters the pestilential and contagious +germs, not only by the air he expires, but by his droppings, and after +death by his mortal remains—his hide, his horns, his entrails, his +flesh—all of which disseminate the deadly germs into the atmosphere, +which afterwards diffuses them in every direction.</p> + +<p><span class='pagenum'><a name="Page_289" id="Page_289">[Pg 289]</a></span>The germs of this virulent distemper have no doubt smitten some cattle +which appeared in the best health and conditions, those of the rich as +well as those of the poor; but, just in the same manner as the cholera +chiefly fixes itself upon the sickly, the ill-fed, the unclean, upon +those who live in crowded dwellings and badly ventilated rooms; so, too, +does the typhus choose its victims among the stalls and stables of those +graziers who keep their cows tied up for years to the rack, giving them +neither air nor exercise, and feeding them, not on that diet which their +health requires, but on those things which add to their milk and +increase their flesh. It follows, of course, that the greater number of +these cows, more or less disordered by this long course of baleful +treatment, and many of which die of consumption, after their +deteriorated milk has infused into men the seeds of diseases, must +afford an easy prey to the typhus, <i>to receive which they seem almost +expressly to have been trained</i>.</p> + +<p>It is highly important then, farmers and graziers, that you should be +able to recognise this ox-typhus; in the first place, that you may take +the necessary measures to prevent its <span class='pagenum'><a name="Page_290" id="Page_290">[Pg 290]</a></span>contagion; and secondly, that you +may apply the treatment which shall have been recommended to you.</p> + +<p>You must at all times, but above all when the contagious disease is +raging, keep a watchful eye on your cattle. If you notice in their gait, +in their looks, about their ears, any unusual signs; if they seem to you +less eager, less active, less vigilant, if they leave any part of their +rations when in the stables, or if, when in the fields, they no longer +browse with that continual alacrity which sometimes it is difficult to +divert them from, be upon your guard, and dread the outbreak of the +complaint. If to these changes of minor importance is added an appetite +really less acute, if the rumination is less regular, if the animal +looks sad and dispirited, if he exhibits an unwonted look of gloom, if +his leaden eye continues fixed, astonished, be sure a morbid change is +inwardly at work, and that this cruel distemper is spreading through his +frame.</p> + +<p>By-and-bye the animal loses his appetite more and more; rumination is +shorter and less frequent; he holds his head down, his ears sink and +fall; he grinds his teeth. Then as <span class='pagenum'><a name="Page_291" id="Page_291">[Pg 291]</a></span>to the cows: their milk, which was +already diminished, suddenly dries up altogether, and that lowness of +spirits which had been visible for some days before, passes into stupor. +If at this time you touch their horns, their extremities, their hide in +any part, you find that all these different parts are sometimes warm, +sometimes cold. From this day forward you will witness, one by one, a +succession of disorders in the animal's health: partial shiverings at +the attachment of the fore and hind limbs, loud panting breathing, with +slight cough, the urine scanty and thick, the droppings hard and +constipated, and finally, general excessive warmth. If you press the +back the pressure will be painful, and all the signs of intense fever +will be manifest.</p> + +<p>Already these indications have divulged the nature of the malady you +have to deal with; but others more significant succeed them which remove +every doubt. The breathing becomes more hurried and oppressed, more +puffy; from the eyes, nostrils, and mouth there issues a discharge +which, thin and irritant at first, soon becomes thick and purulent, and +of a fetid smell. Diarrhœa takes the place of <span class='pagenum'><a name="Page_292" id="Page_292">[Pg 292]</a></span>constipation; the +sexual organs of the cow are red and inflamed, and furrowed with livid +streaks. The cattle grow leaner and leaner, some of them dying at this +period. If they still hold out, the diarrhœa becomes more frequent, +more fetid, and sometimes bloody; gases are developed under the skin, +along the spine, where they form wide flat tumours, which crackle when +pressed upon with the fingers. Finally, the mucus which runs from the +head becomes still thicker and more fetid; a glutinous foam stops up the +mouth; the eyes, filled with humour, sink in the orbit; the bodily +warmth decreases, the animal sways his head from right to left, becomes +insensible, cold; his head lolls on one side, and he dies, panting, from +exhaustion and asphyxia, the tenth or twelfth day after the disease has +been confirmed.</p> + +<p>The carcass exhibits a repulsive appearance; the hide is dry, +excoriated, and cracked; it sticks to the bones, which show the form of +a skeleton, and the putrid decomposition, which had already set in +before death, seizes rapidly on all the tissues.</p> + +<p>The course of the disease is not always the <span class='pagenum'><a name="Page_293" id="Page_293">[Pg 293]</a></span>same. Sometimes the animal +is agitated at first, and all the functions of life are so disturbed +that death comes on in the two or three first days. At other times, the +lungs are more affected than the other internal organs; the cough is +more intense, the breath hurried and obstructed, the excess of mucus +preventing the air from passing into the chest.</p> + +<p>When once you have seen this disease it is impossible to mistake it for +any other, unless it be the chest complaint called peripneumonia, which +is likewise contagious. But in this disease, as the Report of the Royal +Agricultural Society states, the attack is generally insidious; the eyes +preserve their vivacity, and the appetite is not lost until towards the +close. A short, dry cough shows itself from the outbreak, and persists. +The breathing is frequent and painful; the sides of the chest when +struck with the fingers give out the hard, solid sound of a full barrel, +this percussion being painful. The eyes, nose, and mouth do not +discharge those purulent secretions seen in typhus; the diarrhœa only +comes on at the end, being less frequent and fetid. In the milch cows +the milk decreases, but is not quite <span class='pagenum'><a name="Page_294" id="Page_294">[Pg 294]</a></span>suppressed. The heat of the horns +and lower extremities is retained. The peripneumonia, in a word, runs +its course more regularly, and carries off the animal about the fourth +week. Thus it will be seen that the two distempers widely differ in +their symptoms.</p> + +<p>Every beast which dies of the contagious typhus, bears on its digestive +organs the traces of the malady, more or less strongly marked. The third +and fourth stomachs and the intestines exhibit red or livid patches, and +at other times ulcerations.</p> + +<p>The cattle plague is by far the most formidable malady which can affect +animals. When left to itself, or treated without discernment, it carries +off ninety cattle out of a hundred. In prior visitations, especially +that of 1750, when six millions of horned beasts were swept off in +Europe, England lost from three to four hundred thousand; and we may +suppose that the number of cattle which have perished since last June +exceeds sixty thousand.</p> + +<p><i>The treatment</i> is very difficult, owing to the contagious character of +the disease, and it has given rise to much discussion. In some +countries, the governments, considering the <span class='pagenum'><a name="Page_295" id="Page_295">[Pg 295]</a></span>distemper incurable, only +seek to stamp it out wherever it may appear. They slaughter all the sick +cattle, and even those which had come near them, allowing a compensation +of half the value of the beast. This measure has not always proved +successful, the disease having in spite of it sometimes extended over +the whole of the country thus defended from its diffusion.</p> + +<p>England protected by the sea, and which has been spared for a century, +was taken somewhat unawares, so that some uncertainty has been witnessed +in the measures employed to arrest its course. In some districts, the +parties interested have had the good sense to form assurance funds; and +it is much to be regretted that the same plan has not been adopted for +the metropolis.</p> + +<p>But we cannot help what has been done; let us, therefore, be reconciled +with the past, and see what is best to be done in future for the +interests of all. What is the present state of the matter? A certain +number of districts, both in England and Scotland, are still exempt from +the typhus; in others the disease is generally extending its ravages.</p> + +<p>Those districts which hitherto have been <span class='pagenum'><a name="Page_296" id="Page_296">[Pg 296]</a></span>spared, should institute +assurance funds, and take every precaution to secure themselves against +this scourge. In France, in Belgium, even in Great Britain, some places +managed, in 1750, to successfully protect themselves by prohibiting the +importation of any foreign cattle or animal. These preventive measures +may now be taken with some chance of success in certain parts. Ireland, +which, thanks to the published Orders in Council, seems to have escaped +up to this time from the contagion, shows us the effectual results of +these sanitary measures.</p> + +<p>As for the districts already infected, it is of the highest importance +to send no more tainted beasts to the different fairs and markets, +otherwise the distemper will spread indefinitely: the unsold cattle, the +sheep, the pigs, which are placed only a few yards apart, must +necessarily convey the contagion everywhere. It would even be necessary +at this time not to collect oxen and other animals together in the same +markets; we urgently invite the attention of all public authorities to +this most important question.</p> + +<p>At all events, the farmers and graziers who, after all the cautions they +have received, all <span class='pagenum'><a name="Page_297" id="Page_297">[Pg 297]</a></span>the orders which have been published, and all the +dangers which have been clearly exposed to them, should still persist in +driving their cattle out of their abodes, would deserve censure, and +ought to be heavily fined. The best they can do, since the contagion has +not been prevented, is to submit their cattle to the treatment which we +are now going to explain to them in detail.</p> + +<p>It has been abundantly proved by the many convictions at the various +police courts, that the flesh of cattle seriously diseased has been sold +to the consumers, to the great injury of the public health; and if the +cholera, which is steadily and surely advancing towards us, should mix +its fatal germs with those of the ox-typhus, we must all expect +deplorable consequences, in case the flesh of tainted oxen should +continue to be sold by the butchers, as during the last three months it +has been.</p> + +<p>Every farmer or grazier who shall have fully ascertained that the ox +typhus has insinuated itself into his farm or his stables, must +instantly have recourse to the necessary measures and safeguards by +means of which he may limit its pernicious influence, and prevent <span class='pagenum'><a name="Page_298" id="Page_298">[Pg 298]</a></span>the +spread of the contagion to his other cattle still sound and healthy. Let +him immediately divide his stock of animals into three classes or +lots—the first class must consist of healthy cattle, having had no +direct contact with the infected beasts; the second class must contain +those cattle which, though not yet sick, may become so, because they +have been in contact with those tainted; the third class will be +composed of cattle smitten with the typhus.</p> + +<p>The sound and healthy cattle forming the first class must be removed +from the farm, and driven to the field separately, by some other road, +in different pastures, and only after the dispersion of the morning +mists. Those which are accustomed to continue at the rack must be taken +out twice a day, for the twofold object of taking wholesome exercise, +and allowing their stalls and sheds to be cleaned.</p> + +<p>Their feeding must be attended to and watched with very particular care; +the rations of those which were being fattened up must be decreased, and +they ought to be sold to the butcher for consumption as soon as +possible. <span class='pagenum'><a name="Page_299" id="Page_299">[Pg 299]</a></span>Let the following provisions be added to their daily +sustenance:</p> + +<div class="centered"> +<table border="0" width="55%" cellpadding="2" cellspacing="0" summary="png 309"> + <tr> + <td class="tdl" width="60%">Pounded oats</td> + <td class="tdl" width="40%">4 pounds.</td> + </tr> + <tr> + <td class="tdl">Pounded juniper berries</td> + <td class="tdl">1 pound.</td> + </tr> + <tr> + <td class="tdl">Powdered gentian</td> + <td class="tdl">1 ounce.</td> + </tr> + <tr> + <td class="tdl">Sulphate of iron</td> + <td class="tdl">2 drachms.</td> + </tr> + <tr> + <td class="tdl">Carbonate of soda</td> + <td class="tdl">2 drachms.</td> + </tr> +</table> +</div> + +<p>The herdsman who tends the cattle whilst feeding in the fields must have +them cleaned every day: he will carefully wash and scrub them; he will +not allow them to drink out of the ponds, or at any stagnant and muddy +watercourse.</p> + +<p>Those belonging to the second class must receive the same strengthening +and tonic ration in the morning; and, twice every day, one of the +following anti-contagious preparations: either a solution of <i>chlorate +of potash</i> or of <i>permanganate of potash</i>; two drachms of either of +these salts dissolved in eight ounces of warm water, mixed afterwards +with a gallon of an infusion of sage or hyssop, just at the time when +the drink is given to them.</p> + +<p>Or you may employ, for the same purpose, a solution of arseniate of +soda—two grains dissolved in four ounces of water, and mixed <span class='pagenum'><a name="Page_300" id="Page_300">[Pg 300]</a></span>with +their drink in the same way. You need hardly be told that these doses +must be reduced one half, when you have to treat a calf or a heifer, and +that the same diminution will hold good, in their cases, for all other +medicaments. <i>The use of these anti-contagious drinks is of the highest +importance; I recommend you earnestly to study their effects, and to +continue them even after the distemper shall have broken out.</i></p> + +<p>These drinks having no disagreeable taste, the cattle take to them in +general; should the contrary be the case, give them in a bottle as all +men who are cattle owners know how to do.</p> + +<p>If the health of any of these animals among which the outbreak of the +typhus is apprehended should seem below the standard, you must apply a +purgative to those whose bowels do not operate well, and even have +recourse to bleeding in exceptional cases.</p> + +<p>During the absence of those cattle which are undergoing the preventive +treatment, let the hygienic conditions of their stalls and sheds be +looked to; for no circumstance must be overlooked or neglected if we +hope to withstand <span class='pagenum'><a name="Page_301" id="Page_301">[Pg 301]</a></span>the propagation of so formidable a malady. Be careful +to take out the litter every day, to wash the floor and cleanse it of +the droppings, to ventilate the place thoroughly, to fumigate it with +burnt sulphur or aromatic plants, such as juniper berries, sage, +rosemary, salted with nitrate of potash and arsenic acid; in order to +promote the combustion and give effect to its disinfectious properties. +At night, camphor or tar, or naphthaline, or creosote, or even iodine, +may be left in the stable to diffuse their vapours; all these measures +are very effectual in modifying the air.</p> + +<p>Let us now see what must be done with respect to the sick animals +themselves.</p> + +<p>The typhus, as we have said, when once it is developed in an ox or cow, +usually pursues its fatal course until the last period of its cure; +generally death alone can arrest its march. Besides, the disorders which +this disease produces in the various functions of the body are not the +same at the different stages of its duration. Thus, for instance, the +fever produces great excitement in the beginning, but later it produces +exhaustion. Without being a physician, a man can understand that the +treatment to be <span class='pagenum'><a name="Page_302" id="Page_302">[Pg 302]</a></span>applied to these different states ought not to be the +same. We must, moreover, observe that the typhus is of all known +distempers the most difficult to treat. It requires in the doctor a +degree of skill, of practical experience, vigilance, decision, and +sureness of hand which no man can be expected to possess at the first +outbreak of the epizootia.</p> + +<p>On the other hand, the constitution of the ox, so easily shaken, +undergoes in two weeks all the commotion which a man labouring under +typhoid fever would be subject to in a month. The phenomena succeed each +other with terrific swiftness, leaving scarcely time for us to act, or +for the medicines to operate. Do not, therefore, marvel at the great +mortality among your cattle, and at my repeated recommendations of the +preventive treatment by means of inoculation.</p> + +<p>At the outbreak, you must reduce the violence of the fever, prevent the +derangements in connexion with the nervous centres, assuage the thirst, +empty the stomachs and intestines, which will be the principal seat of +the complaint, and sometimes let blood.</p> + +<p>But how are you to obtain these results? <span class='pagenum'><a name="Page_303" id="Page_303">[Pg 303]</a></span>By abolishing the solid +feeding, which is easily done, since the animal has lost his appetite. +Give him to drink, three or four times a day, half a pailful of a +decoction of good hay, adding thereto a sprinkling of salt; or a +decoction of wall-wort, with a drachm of nitrate of potash; or water +whitened with bran and flour, or whey, with a little vinegar. If the +animal has a tendency to cold, if he coughs, if his breathing is +oppressed, give him warm drinks, consisting of an infusion of mallow +leaves and borage, or else a light decoction of barley and oats, and +cover the animal's body warmly over.</p> + +<p>Now, with respect to purgatives: give the animal, night and morning, +according to the effect produced, 6 or 8 ounces of Epsom salts (sulphate +of magnesia), or an equal dose of Glauber's salt (sulphate of soda), +dissolved in two pints of honey-coloured water; or 12 ounces of linseed +oil in some warm drink; or a decoction of senna leaves and prunes, with +an ounce of sulphate of soda added thereto.</p> + +<p>We might point out a larger number of purgatives, but we shall desist +from so doing. Those which we have just prescribed, not <span class='pagenum'><a name="Page_304" id="Page_304">[Pg 304]</a></span>being irritant +to the intestines, are the best which can be employed.</p> + +<p>If the animal is very restive, if he passes through alternate fits of +dejection, stupor, and great excitement, you must have recourse to +bleeding, particularly local bleeding, by opening the small veins of the +head. If the excitement does not abate you must add, night and morning, +to one of his drinks, 2 grains of extract of belladonna, or a half ounce +of powdered belladonna leaves. If the fever, at first, is irregular, and +tends to become malignant, you must then have recourse to sulphate of +quinine, 20 grains in the morning, and the same quantity during the day.</p> + +<p>When the disease is principally seated in the lungs, add to one of the +pectoral drinks 4 ounces of oxymel of squills, and 2 grains of opium, +giving also an emetic—5 grains of tartar-emetic to 4 pints of water—to +be taken in four times, at intervals of two hours.</p> + +<p>Whilst this medication is applied to the internal organs, let the animal +have unusual care taken of him; let his head be washed several times a +day with vinegar and water.</p> + +<p>Such is the course of treatment to be <span class='pagenum'><a name="Page_305" id="Page_305">[Pg 305]</a></span>adopted during the first three or +four days. It must be, of course, followed methodically, watching and +obeying the signs of nature. The purgatives must not be given on those +days when the sick animal is bled, and the doses must vary with the +effects they produce.</p> + +<p>From the fourth to the seventh day the symptoms change, diarrhœa +shows itself, and the running appears at the nose, mouth, and eyes; you +must then continue the use of purgatives, but the dose must be weaker. +Those mentioned above are suitable in every way. The drinks, too, +continue the same. Sometimes, at this period of the disease, the animal +is utterly cast down, nothing can draw him from his stupor: he lies down +the whole day; in this case you give him acetate of ammonia, from 1 to 6 +ounces, in a pint of water, gradually increasing from 1 to 2 ounces a +day, according to the effect produced; and meanwhile, plain +non-acidulated drinks should be administered.</p> + +<p>At this stage of the disease it is right to assist the depurative work +of nature. This is effected by inserting a seton in the neck, <span class='pagenum'><a name="Page_306" id="Page_306">[Pg 306]</a></span>and the +secretion of this issue is kept up by means of such an ointment as the +basilicon with powdered cantharides. Finally, the mouth, nose, and eyes +must be washed very often with an infusion of camomile and sage.</p> + +<p>At the last period of the distemper, the beast sinks into a state of +general exhaustion; his life seems all but extinguished through excess +of weakness. You must now sustain and keep him up by every possible +contrivance; give him bitter and stimulating drinks, beer diluted with +water, adding thereto some powder of Peruvian bark, or sulphate of +quinine. This is prepared by steeping in 8 pints of boiling water, +Peruvian bark, gentian root, centaury leaves and flowers, and hops, 1 +ounce of each; or else prepare a drink consisting of veterinary treacle, +extract of juniper, 1 ounce of each, dissolved in 2 ounces of alcohol, +and then mixed with 3 pints of water.</p> + +<p>When the diarrhœa becomes fetid and bloody, give, night and morning, +a clyster composed of a decoction of Peruvian bark, and a teaspoonful of +powdered charcoal from the poplar, well sifted. If the running from the +<span class='pagenum'><a name="Page_307" id="Page_307">[Pg 307]</a></span>nostrils begins to stop, you must inject into the nasal orifices some +spoonfuls of a sternutatory solution, thus composed—</p> + +<div class="centered"> +<table border="0" width="55%" cellpadding="2" cellspacing="0" summary="png 317a"> + <tr> + <td class="tdl" width="60%">Spanish pepper</td> + <td class="tdl" width="40%"> 1 ounce.</td> + </tr> + <tr> + <td class="tdl">Essence of turpentine</td> + <td class="tdl"> 1 ounce.</td> + </tr> + <tr> + <td class="tdl">Camphor</td> + <td class="tdl"> 2 drachms.</td> + </tr> + <tr> + <td class="tdl">Vinegar</td> + <td class="tdl"> 2 pints.</td> + </tr> +</table> +</div> + +<p>Should any sores form on the skin, or should they arise from the opening +of purulent deposits, dress them with the following ointment—</p> + +<div class="centered"> +<table border="0" width="55%" cellpadding="2" cellspacing="0" summary="png 317b"> + <tr> + <td class="tdl" width="60%">Acetate of copper</td> + <td class="tdl" width="40%"> ½ a drachm.</td> + </tr> + <tr> + <td class="tdl">Calcined alum</td> + <td class="tdl">20 grains.</td> + </tr> + <tr> + <td class="tdl">Sal ammoniac</td> + <td class="tdl">20 grains.</td> + </tr> + <tr> + <td class="tdl">Camphor</td> + <td class="tdl"> ½ a drachm.</td> + </tr> + <tr> + <td class="tdl">Common ointment</td> + <td class="tdl"> ½ an ounce.</td> + </tr> +</table> +</div> + +<p>If the natural heat diminishes greatly, if the chill reaches the hams +and skin, let the beast be rubbed all over, three times a day, with +wool, moistened with the following liniment—</p> + +<div class="centered"> +<table border="0" width="55%" cellpadding="2" cellspacing="0" summary="png 317c"> + <tr> + <td class="tdl" width="60%">Laurel oil</td> + <td class="tdl" width="40%"> ½ an ounce.</td> + </tr> + <tr> + <td class="tdl">Green soap</td> + <td class="tdl"> ½ an ounce.</td> + </tr> + <tr> + <td class="tdl">Volatile oil of lavender</td> + <td class="tdl"> ½ a drachm.</td> + </tr> + <tr> + <td class="tdl">Solution of ammonia</td> + <td class="tdl"> ½ a drachm.</td> + </tr> +</table> +</div> + +<p>Simultaneously with the above, give the <span class='pagenum'><a name="Page_308" id="Page_308">[Pg 308]</a></span>following cordial, to be drunk +in two draughts—</p> + +<div class="centered"> +<table border="0" width="55%" cellpadding="2" cellspacing="0" summary="png 318"> + <tr> + <td class="tdl" width="60%">Cinnamon</td> + <td class="tdl" width="40%"> ½ an ounce.</td> + </tr> + <tr> + <td class="tdl">Extract of gentian</td> + <td class="tdl"> 1 ounce.</td> + </tr> + <tr> + <td class="tdl">Red wine</td> + <td class="tdl"> 2 pints.</td> + </tr> +</table> +</div> + +<p>Should the animal fall into a state of lethargy, you must have recourse +to strokes of fire, according to surgical usage.</p> + +<p>This distemper must extend to its extreme degree of gravity before it +advances towards its cure; you need, therefore, not despair until the +last moment. At this period of exhaustion, the drinks above-mentioned +are given up, or you add nutritive beverages to them, such as beef-tea, +fat soups, milk, and farinaceous drinks.</p> + +<p>If the animal holds on, and his appetite returns, which will be shown by +the desquamation of the nostrils, by the return of rumination, by the +habit of the beast to look right and left, to question you in a manner, +add cut straw to his nutritive drinks: send him out every day into the +open air, and let him return by slow degrees to his habitual feeding. +But it is extremely important to watch the intestinal functions; to +diminish and change the food, <span class='pagenum'><a name="Page_309" id="Page_309">[Pg 309]</a></span>if the diarrhœa returns; as such +relapses often cause the death of an animal considered out of danger.</p> + +<p>Such, then, farmers and graziers, is the treatment to be opposed to the +ox typhus: it is simple as respects the remedies, and I have deemed that +it ought to be so, in order that the medicines prescribed might be had +everywhere, and at a cost which the poor man could command as well as +the rich. The disease is variable, it is not always equally deadly; and +there comes a moment when in some sort it cures itself, with a little +assistance and watching. The great point is, to be careful and vigilant, +to attend to nature and the instincts of the suffering cattle, and lend +yourselves to both.</p> + +<p>I cannot reproduce here the instructions given by the Privy Council to +protect your cattle from contagion, and above all not to propagate it, +but I shall refer you to Doctor Thudichum's <i>Memorandum</i>, page 257. This +exposition is too complete to need anything added to it by me; study it +well; let it be your monitor and guide; read it over again and again; +your own interests and those of the <span class='pagenum'><a name="Page_310" id="Page_310">[Pg 310]</a></span>whole country depend on the manner +in which you shall treat this admirable warning.</p> + +<p>There are in this disease, as in every other, unforeseen varieties and +complications, such as those which are brought on by the gestation and +abortion of cows, and those proceeding from prior disease; for these +accidents you will provide. Moreover, such a terrible distemper can only +be treated according to the advice of a professional man. Call him in, +then, follow his advice and prescriptions with rigid exactness, and do +not attempt to do better than he; and, above all, arm yourselves against +the insidious pretensions of quacks and charlatans, whatever mantle they +may put on to hide their ignorance.</p> +<br /> +<br /> +<br /><span class='pagenum'><a name="Page_311" id="Page_311">[Pg 311]</a></span> +<br /> + +<hr /> +<br /> +<h2>FOURTH PART.</h2> + +<div class="blockquot"><p class="hang" style="margin-left: 2em;"><i>Suggestions on the Improvements to be effected in the Study +of Medical Science, in order that we may be in a Condition +to confront Diseases generally, but Epizootic and Epidemic +Diseases in particular.</i></p></div> +<br /> + +<p>The epizootia of bovine typhus which is now extending its unrestricted +ravages over this island, and which has assumed the magnitude of a +general calamity, has naturally excited and stirred up the public mind. +Thoughtful and earnest men could not look on and witness unmoved the +ever progressive march of the scourge; but each observer has, +consistently with his means and qualifications, striven to find a remedy +to resist the evil. Thus, we have seen, and with respectful interest we +have watched, the gentlemen of the press, and other men of letters, +economists, scientific men, and, above all, physicians, producing from +day to <span class='pagenum'><a name="Page_312" id="Page_312">[Pg 312]</a></span>day in the newspapers articles and letters of remarkable merit +on the all-engrossing subject of this epizootia. The re-opening of the +medical colleges furnished the skilful professors at their head with a +seasonable opportunity to consider this dire distemper, according to the +views of general pathology and medical philosophy, and this they have +done with unquestionable talent and ability. Still, something remains to +be said on this important matter, and since I have taken up my pen, like +others, I wish to mingle my voice with that of my brethren, and inquire +whether the time is not come to avail ourselves more fully than we have +done yet of the grand discoveries of the exact sciences, which, with +respect to the science of medicine, are the instruments of its progress. +And my object in doing so, is, that we may, as far as possible, rise to +a level with the ordeal which the future may have in store for us.</p> + +<p>Medicine is at once an art and a science. An art it has been at all +times, and in every age of civilized man; but it became a science only +when human knowledge had acquired a certain expansion; when natural +phenomena had been <span class='pagenum'><a name="Page_313" id="Page_313">[Pg 313]</a></span>tested and explained; when mathematics, physics, +chemistry, botany, general anatomy, general pathology, had enabled the +inquiring physician to study with important results whatever belongs to +his theme; to understand the serial chain and connexion of bodies with +each other, in the mineral, vegetable, and animal kingdoms, and to +investigate their immutable laws. Uric acid, as we see with the +microscope, will always crystallize in rhombohedrons, according to a +fixed law; the vegetable cell, the germination of a seed, must obey, and +always submit to, the innate and indestructible forces inherent in them. +That which is true in the vegetable is true in the animal world, as +regards the pre-established order which regulates and controls the +phenomena of life. These laws which govern the development of organic +phenomena being immutable and everlasting, permit the different +generations which succeed each other on our globe to build upon a +durable basis, which certifies to the slow and laborious, but +irresistible march of human progress.</p> + +<p>Medical science being in truth only the application of other positive +sciences to the <span class='pagenum'><a name="Page_314" id="Page_314">[Pg 314]</a></span>preservation of health and the cure of diseases, +continues like them to perfect itself incessantly; but all it can do is +to follow them at a distance, and it can never hope to reach their +degree of superiority.</p> + +<p>These are truths which have been long admitted and felt by us. +Therefore, we have appealed for assistance to the discoveries of the +natural sciences: physics, chemistry, have in our hands become effectual +means of observation and analysis; and we, in our age, gain more +knowledge in fifty years than our forefathers did in several centuries, +for they were then necessarily rather artists than scholars. In a word, +medical science or biology is constituting itself, and if it be fully +conscious of its impotence in the case of many diseases, it also knows +its progressive improvement. It is striving to achieve the highest place +among social institutions, and the day may come when it shall obtain it, +for nations will then owe to us their health and life—that is to say, +their earthly happiness.</p> + +<p>The laws by which organic phenomena are regulated, are, we have said, +everlasting; we may also declare that they are general. One of <span class='pagenum'><a name="Page_315" id="Page_315">[Pg 315]</a></span>these +laws common to the plant, to the shell, to every species of vertebrata, +reappears in man, whose organization comprises all the functions divided +among the other organic kingdoms. Not only does the organization of man +obey the laws which govern the vital phenomena of other animals; not +only does he possess their organs and functions, but he is a tributary +subject to their diseases. So that the knowledge of the laws affecting +the functions and diseases of those creatures which are placed below him +in the scale of animals ought to be the first foundation of all medical +study.</p> + +<p>These truths are too manifest to be new; they are written and professed +everywhere, and every one amongst us has received general notions of +comparative anatomy and physiology at the beginning of his course of +study. But let us admit that these notions only served to expand the +circle of our knowledge and ideas, and that we seldom or never apply +them to the practice of our art. It would have been very different had +we received at the beginning of our medical novitiate, not merely in +theory and books, but practically and experimentally, precise notions of +anatomy, physiology, and, <span class='pagenum'><a name="Page_316" id="Page_316">[Pg 316]</a></span>let me add, of the <i>pathology of all +animals</i>. Let us suppose for a moment that the task had been imposed +upon us before entering upon the study of human maladies, to observe the +structure of plants and animals, to submit their tissues to +microscopical examination and chemical analysis; to study experimentally +all their functions and diseases, and acknowledge that had such been the +case, the anatomy, physiology; and pathology of man would have been far +better understood, and that most of the difficulties against which we +now contend in vain in our helplessness, might easily have been +overcome.</p> + +<p>Comparative anatomy and physiology are the first conditions of all +medical instruction of a serious character; there can be no doubt on the +subject, but the evidence being not perhaps so palpable with respect to +comparative pathology, it will not be useless, therefore, to enter into +fuller particulars as to this subject.</p> + +<p>We know not whether any one has ever sought to retrace the first origin +of our diseases in the animal kingdom, but it would undoubtedly be a +study of great scientific interest. <span class='pagenum'><a name="Page_317" id="Page_317">[Pg 317]</a></span>As for us, we gladly believe that +man, created to be the sovereign lord of the earth, did not originally +receive the principle of every organic disease with which we see him +affected. It seems to us probable that he was created sound in body and +in mind, but unequal is his vital powers, and in his faculties and +talents, the social functions being various and dissimilar, and subject +to physical and moral infirmities. We think it likely that plants and +animals, from which, in course of time, man's substance is formed, have +transmitted the first causes, the germs of some organic diseases with +which they were themselves affected. We see in this transmission of +animal diseases to man, a connecting link, which appears to us to be a +condition of harmony, order, peace, and happiness among all living +beings. It seems to us that the first injunction of a legislator should +be—<i>love other animals like yourselves</i>; for if man had practised this +maxim, he would have logically applied the same to his fellow-creatures; +and no doubt, with such principles to guide them, past generations would +not have bequeathed to us the innumerable calamities we have had to +deplore.</p> + +<p><span class='pagenum'><a name="Page_318" id="Page_318">[Pg 318]</a></span>We think that we receive from animals some of their diseases, because +the fact is palpably evident; thus they have parasitical diseases, such +as favus, tænia, psora, trichinosis, which they transmit to us. They are +likewise smitten with small-pox, typhoid fever, and with typhus; and +under certain given conditions they may transmit them to us. They die of +consumption and cancer, and it is probable that they transfuse into us +through their milk and flesh the germs of these diseases. Finally, we +have our epidemics as they have their epizootics; and here we will limit +our instances of this reciprocation.</p> + +<p>It is certain that the study of these maladies in animals would have +been for us the source of precise knowledge, which, if well understood +and explained, would have often led to their preventive treatment. This +is what has occurred in the case of small-pox; it is what will one day +occur in typhoid fever, in times of epidemic, as will be the case in a +certain number of other general or local diseases.</p> + +<p>In truth, some complaints now looked upon as inherent to the human +species, were originally foreign to it; most parasitical diseases +<span class='pagenum'><a name="Page_319" id="Page_319">[Pg 319]</a></span>belong to this class. Thus man has not the <i>psora</i>, or itch—the +disease does not properly belong to him; the parasite which engenders it +is not bred in him, it is always transmitted to him by animals. It is +the same with the tænia, or tape-worm, with the trichina, or fine +hair-worm.</p> + +<p>Medical science, instituted on the bases of comparative pathology, would +have made the study of diseases in the brute creation, not the +collateral, but the principal object of its inquiries. It would have +applied itself to the cure of the lower animals; and whilst learning to +cure them, it would have ensured the cure of men's diseases.</p> + +<p>If such be the case, can any one believe that the treatment of diathetic +and hereditary maladies would be, as they still are, insoluble problems; +and that the physician would have the misery of seeing decimated, whilst +he helplessly looks on, a large part of the population, condemned +inevitably to die of consumption and cancer? Would every man smitten +with hydrophobia be irrevocably condemned to death? Assuredly, it would +not be so.</p> + +<p>That the physician should have been reduced <span class='pagenum'><a name="Page_320" id="Page_320">[Pg 320]</a></span>to the painful necessity of +confessing his want of means, when medicine could be nothing more than +an art, we admit; but now that science has grown up and come of age, +society has a right to challenge him to do, what in past ages could not +have been expected of him. Briefly, we think that the time is come, by +blending comparative pathology with anatomy and physiology, to construct +one of the bases of the tripod on which medical science will have to +rest. The success which has already been achieved in this direction is a +certain guarantee for those which we may hope for hereafter.</p> + +<p>Such is our deep conviction, and perhaps we have some title to speak out +decidedly on this point, as we have long since exemplified our precepts +by actual proofs.</p> + +<p>Persuaded for many years that comparative pathology afforded to +industrious men a new mine, rich in precious veins for working, we +several times endeavoured to explore this fertile field. But, +unfortunately, our means of action not being consistent with our +sanguine expectations, we were repeatedly compelled to suspend our +pursuits, until at last we found at the <span class='pagenum'><a name="Page_321" id="Page_321">[Pg 321]</a></span>Ecole Vétérinaire d'Alfort, the +favourable opportunity and the essential conditions of which we had so +long been in quest.</p> + +<p>Grieved at our helplessness to stay the ravages of pulmonary +consumption, I formed one day the resolution to study that wasteful +complaint in animals in order to discover, or at least to look for, the +required remedy. With that view, I confined in a dark, cold, and damp +cellar a number of animals to practise on: birds of different species, +rabbits, a monkey, a dog, &c. To these animals I dealt out a deficient +quantity of food. The monkey, as might have been expected, was the first +to be affected, since in our climates they all die of consumption. Next, +and for the same reason, it was the parrot's turn; then the chickens and +ducks died; after them the rabbits;—in fine, at the end of fourteen +months, the dog alone survived. All the rest had sunk under consumption, +and exhibited tubercles in different organs—in the lungs or mesentery.</p> + +<p>It was then necessary to have the counter-proof: to place a second set +of animals in the same conditions, to produce the disease again, and +attempt its cure. But the first experiment <span class='pagenum'><a name="Page_322" id="Page_322">[Pg 322]</a></span>had been a long one, and I +was forced to relinquish the inquiry, which, moreover, was above my +means at that period.</p> + +<p>On another occasion, it seemed to me strange that we should be obliged +to open the bladder of patients suffering from the stone, or to subject +them to lithotrity, which has also its perils. Nature, I said to myself, +forms calculi by uniting organic elements, by crystallizing them, and by +cementing them with vesical mucus. But would it not be possible to cure +the disease by employing contrary means—dissolving the calculi in the +bladder by means of continued injections, changing the chemical agents +according to the composition of the calculus, and adding thereto the +action of a galvanic current?</p> + +<p>After this, I pursued my inquiry in this direction. I studied for +several months the chemical composition of calculi by examining them in +their dissolved state; and I saw that those in which the alkaline bases +prevailed, being submitted to a diluted solution of tartaric acid, which +would not injure the bladder, crumbled after a time; that the calculi +with excess of acid were also attacked by an alkaline <span class='pagenum'><a name="Page_323" id="Page_323">[Pg 323]</a></span>solution; in +fine, that the calculi of oxalate of lime alone seemed to resist the +action of these chemical solutions. But it is well known that they +sometimes defy all lithotrite instruments, and compel us to have +recourse to the knife.</p> + +<p>These preliminary experiments over, it was necessary to come to their +application, and for that purpose to make experiments on some animals. +The canine species, omnivorous like ourselves, was chosen in preference. +Bitches were selected to be practised on; for as their urinary passages +are wider and more flexible, it enabled me to insert in the bladder +fragments of calculi already analysed, which were to serve as the nuclei +to the stones they were intended to develop.</p> + +<p>This second assortment of animals, penned up apart from each other, were +supplied with different modes of sustenance: some of them were put upon +a diet of meat only, others on a farinaceous diet, and a third set on a +mixed course of food. These experiments were being regularly followed +up, when an important and unforeseen event compelled me to desist at the +end of six months. The poor animals were destroyed; but all of them, as +I <span class='pagenum'><a name="Page_324" id="Page_324">[Pg 324]</a></span>had anticipated, had generated calculi of various chemical +composition.</p> + +<p>These unfinished inquiries concerning comparative pathology, thus +interrupted in spite of myself, might, had circumstances allowed them to +reach the goal, have authorized us to undertake in man the dissolution +of stone in the bladder. And how would this have been effected? By +seizing the stone between the two ends of the catheter with the double +current, and by injecting a well-sustained series of dissolvents into +the patient, whilst lying at his ease in a recumbent posture.</p> + +<p>Nor is this all. They would likewise, I believe, have thrown some light +on the organic production of calculi, on the lithic diathesis, and the +particular formation of the stone; and led us, in some degree, to their +preventive treatment, which is always superior to the curative remedy.</p> + +<p>On a subsequent occasion, I betook myself to my task under more +favourable conditions. I undertook at Alfort, conjointly with Professor +Delafond, a course of experiments on the cutaneous diseases of animals +in relation to comparative pathology, having already, <span class='pagenum'><a name="Page_325" id="Page_325">[Pg 325]</a></span>whilst walking +the hospitals, published a work on the "Entomology and Pathology of +Psora in Man," which had been printed at the expense of the Academy.</p> + +<p>These inquiries and examinations at Alfort were persisted in for five +years, and were considered to have led to very satisfactory results as +regards general pathology. But I have spoken of these labours in the +first part of my book.</p> + +<p>Pardon me, reader, and do not suppose that vanity or any desire to +parade myself has induced me to refer to these experiments. No; my only +object is to show to what results similar studies might lead, if they +were executed on a large scale and on the whole animal kingdom; if, +instead of these partial efforts made under favour, some special and +appropriate medical institution encouraged earnest experimentalists, +supplying them without stint with all necessary resources, and with the +best and completest instruments of observation.</p> + +<p>Will any one deny, that if medical science had been settled on this +foundation fifty years ago—that is to say, since the exact sciences +<span class='pagenum'><a name="Page_326" id="Page_326">[Pg 326]</a></span>first began to provide us with the means of investigation, it would now +be so impotent? Epizootias and epidemics would not thus flout us as they +do; the cholera would no longer be an enigma, nor the ox typhus so +incurable. No! a hundred times no! Medical science would not he helpless +and impotent in our day, had our forerunners been more mindful and +provident.</p> + +<p>But, instead of this, the science for which we plead would have done +good work. It would have made and confirmed an infinite variety of +observations on the brute creation; it would have transmitted our +diseases to them as they transmit their diseases to us; it would have +treated and cured these diseases, and every such cure would have been a +new triumph, a new victory for mankind.</p> + +<p>For instance, during an outbreak of cholera, this science would have +been ready and prepared to try different experiments on men and animals; +it would first have communicated the cholera to animals, and then +submitted them to a variety of experimental treatments. This cholera, +which is not an infectious fever, with its regular and assigned periods, +like <span class='pagenum'><a name="Page_327" id="Page_327">[Pg 327]</a></span>typhus, and which we are not obliged to suffer to run its course, +but which, on the contrary, is a nervous affection produced by some +poisonous miasma, the toxical effects of which first of all assail the +nervous system and then more particularly the great sympathetic; the +cramps being but the result of a reflective action—<i>this cholera, we +say, must be curable</i>, and well-advised experiments would reveal the +remedy we want for it, nor should we have to wait long for the +revelation.</p> + +<p>As for me, I once made a desperate attempt in this direction. It was +during the cholera of 1854. We remarked whilst dissecting subjects, as +is always the case, that the mucous membranes of the stomach and +intestines, which were in a manner paralyzed, had suffered the fluid +parts of the blood to ooze out on the surface. Hence the cause of those +vomitings, and those watery and colourless diarrhœas which nothing +can stop, so that at a given moment the patients die, poisoned, of +course, but dying more particularly through want of circulation, the +blood being reduced to its solid parts and unable to circulate any +longer. Relying on this fact, and trusting for <span class='pagenum'><a name="Page_328" id="Page_328">[Pg 328]</a></span>want of better to the +secondary effects, I strove to restore to the blood its aqueous part, +and, if possible, to re-establish the circulation.</p> + +<p>With this view, I went to the Hôpital de la Charité, provided with all +the requisite instruments. Choleraic patients were being brought there +every hour. The experiments being new, venturesome, and <i>dangerous</i>, in +the eyes of the hospital directors, I was only suffered to operate on +the moribund. The first patient, considered to be in a state +sufficiently desperate to be given up to me, was a woman, forty-five +years old. She was literally insensible, and thoroughly cold. I +hesitated for a moment to try the operation under conditions so +unreasonable, so preposterous—almost upon a corpse. The radial arteries +in the arm had ceased to beat, and the heart alone kept up a feeble +circulation at the central parts. At length I opened the vein, from +which not a single drop of blood proceeded, and taking the usual +measures to prevent the air from having access, I gradually and slowly +injected two ounces of alkaline solution, the process of injection +lasting twelve minutes. It was scarcely over before <span class='pagenum'><a name="Page_329" id="Page_329">[Pg 329]</a></span>the patient +half-opened her eyelids, and looked about her with astonishment; the +pulse became perceptible for a few moments, and all present thought she +was saved. We put a few questions to her; the patient could not answer +us, but she nodded as much as to say "yes," when asked if she felt +better. But this was all we could do in her case. The circulation +stopped again, the patient relapsed into her state of insensibility and +died two hours after the injection.</p> + +<p>The result obtained in this instance had not answered our expectation. +However, the circulation had for a minute or two resumed its course, and +a flash of reason had once more shown itself.</p> + +<p>I thought the experiment ought to be repeated, and accordingly the next +morning I made another trial. The patient this time was a working +shoemaker, thirty-eight years of age, exactly in the same far-gone, +hopeless state as the patient of the day before. In his case, the inward +commotion caused by the injection was more powerful; twenty minutes +after the injection he was able to see, to understand, to speak, to +raise his head; but this vital <span class='pagenum'><a name="Page_330" id="Page_330">[Pg 330]</a></span>recovery was, as in the former case, but +of short continuance, and two hours and a half after the operation the +man expired.</p> + +<p>After these experiments I dissected the two bodies, and then, finding +that their lungs were infiltrated with water, I understood that the +alkaline solution had not been assimilated, that it had stopped in its +passage into the pulmonary parenchyma, to the detriment of the functions +of the hæmatosis. I also understood that the proper injection, instead +of distilled alkaline water, would have been the serum of the blood, +drawn at the very moment from some man or animal.</p> + +<p>The conclusion which I drew from these experiments was that a variety of +operations, made at different stages of the malady, might lead to +beneficial results, especially if we succeeded in transmitting the +cholera to animals, as that would enable us to test a large number of +curative agents and to pursue a methodical course of +experimentalization.</p> + +<p>From all I have said, I infer that life, health, and disease, being +subject to the same laws throughout the whole animal kind, it is certain +that the physician should possess precise <span class='pagenum'><a name="Page_331" id="Page_331">[Pg 331]</a></span>knowledge as to the +organization, the functions, and diseases of animals. That by proceeding +in this manner, we shall advance from the simple to the complex, from +the plant to the animal, and from the animal to man. That we must of +necessity emerge from the state in which we are now entangled <span class="smcap">by +founding and establishing in London a College of the Natural and Medical +Sciences</span>. Every medical pupil might spend two years in this +college, receiving in it an experimental and practical training; he +would devote himself in it to the chemical analysis of all bodies, to +physiological experiments and tests, without limit and of every kind.</p> + +<p>Most deeply do I appreciate the many difficulties and obstacles that +would interfere with the execution of such a design. In our civilized +age, nations seem rather bent on seeking out the means of exterminating +each other than of protecting themselves and animals from epidemics and +epizootias. It is believed that every first-rate kingdom now spends from +400 to 500 millions of francs (16 to 20,000,000<i>l.</i>) annually in +maintaining their land and sea forces, whilst one-half of their +populations are <span class='pagenum'><a name="Page_332" id="Page_332">[Pg 332]</a></span>living in misery and ignorance, in disease and +corruption. The time is not come—shall we ever see it?—to employ the +vital powers of the peoples, to better incessantly their social +condition. Perhaps, by reason of its organization, the Government of +this country would not be authorized to devote 100,000<i>l.</i> or +200,000<i>l.</i> to the establishment of an institution like the medical +college I suggest, notwithstanding its paramount necessity. But England +is in the habit of doing great things independently of the Government. +In default of the ruling powers, then, let me appeal to the national +initiative, for if the spectacle which we are at present witnessing was +not, in the case of England, one of those trials which invigorate a +people by the salutary teachings which they bring; if it did not induce +them to take some energetic resolution by which their interests would be +saved and their power enlarged, it would indeed be a deplorable sign of +the times and make us despair of its future.</p> + +<p>Moreover, to show the urgency of founding a <i>College of Natural and +Medical Science</i>, let us add, that in every other country they are +endeavouring to unite this indispensable <span class='pagenum'><a name="Page_333" id="Page_333">[Pg 333]</a></span>complement to medical +education. The German universities, the Faculty of Paris, have, for +several years past, incorporated a course of comparative pathology, with +the other series of public lectures.</p> + +<p>It is not a mere Utopia that we propose, but an extension and +improvement, all the parts of which are already prepared. If this +College could be thrown open to-morrow, competent professors would be +ready at the call of duty to indite the programme for this instruction +within twenty-four hours; and as for the professors themselves, there +would be enough to choose among the large body of efficient scholars who +do honour to the country.</p> + +<p>If we have been rightly understood, we desire to see established in +London an institution which would afford an equivalent to what exists in +Paris, at the Museum and Collège de France, where numerous courses of +lectures on anatomy, physiology, physics, and chemistry are given. Only +in London this special college would be formed and organized on such a +scale as to bear away the palm from every previous foundation of the +same kind; it would be an institution unexampled in the world, out <span class='pagenum'><a name="Page_334" id="Page_334">[Pg 334]</a></span>of +whose halls would one day come anatomists, physiologists, and +pathologists of the very highest order of excellence.—But organic +matter would not be the sole object of this instruction, for the animal +is something more than matter. Courses of medical history and +philosophy, of really general pathology, would introduce the students to +the grand phenomena of nature, to the great laws which govern the worlds +and the globe; and descending from the heights of science to the +observation of the infinitely minute, they would never forget the +important part of the vital powers, and of that unknown power called at +different times by the names of <span class="Greek" title="Typhos">πνευμα</span>, <i>archéc—mind</i> and +<i>soul</i>.</p> + +<p>The Regent's Park would, we think, be the proper site for this college, +as the contiguity of the Zoological Gardens would afford continual +opportunities for investigating the diseases of animals.</p> + +<p>Moreover, this college would not trench upon or interfere in any manner +with those medical and veterinary establishments which at present exist; +it would ally itself with, and complete them, nothing more. The +<span class='pagenum'><a name="Page_335" id="Page_335">[Pg 335]</a></span>instruction received at this "College of Natural and Medical Science" +would be so useful and necessary, and so attractive withal, that the +sons of the great families would come to it to finish their collegiate +studies, to the great benefit of the country. Other young men, in +considerable numbers, would flock to it from various parts of the world. +The foundation of such an institution would be an epoch in the history +of science, and would give England another claim to the esteem of +nations.</p> + +<p>I conclude, then, with a conviction that a nation which owes to Lord +Bacon, the founder of experimental philosophy, his imperishable book on +the <i>restoration, the method and teaching of the sciences</i>; to Harvey, +the circulation; to Priestley, the constitution of chemistry; to +Sydenham, the modern Hippocrates, his treatise on "Practical Medicine"; +to Jenner, vaccination; and to Charles Bell, the discovery of the +sensitive and motor nerves—is a people too great and too enlightened to +retrograde; and that, if the epizootic of ox typhus did find them at +first unready and disarmed, they will in the end convert this <span class='pagenum'><a name="Page_336" id="Page_336">[Pg 336]</a></span>disaster +into a new source of greatness and strength.</p> + +<p>Such is the sincere hope which I cherish and the prayer I offer up for +the happiness of a country which, for the future, has become my own.</p> +<br /> +<br /> +<br /><span class='pagenum'><a name="Page_337" id="Page_337">[Pg 337]</a></span> +<br /> + +<hr /> +<br /> +<h2>APPENDIX.</h2> +<br /> + +<p class="cen"><span class="smcap">Note A.</span><a name="Note_A" id="Note_A"></a></p> + +<p class="right"><span class="smcap">Bremen</span>, August 30.</p> + +<p>The following report, drawn up by two German veterinary surgeons, of a +recent visit to London to examine into the cattle murrain, has been +furnished by the agent of the North German Lloyd's at Nordenhamm:—</p> + +<p>"On Wednesday, the 9th instant, we, the undersigned, were requested to +be at Nordenhamm, if possible, the following morning. Upon our arrival +we were asked by the agent of the North German Lloyd's, who had +consulted with several of the chief cattle exporters, to undertake a +voyage to London at once in the steamer <i>Schwan</i>, in the interest of the +cattle export from the Weser. The object of our mission was, first, to +examine as closely as possible into the epidemic cattle disease raging +in and around London for some time past; then carefully to observe the +treatment of cattle upon the vessel during the voyage, upon arrival, and +at the time of disembarkation; lastly, to use every means in our power +to prevent obstacles being opposed to the continued export of cattle +from these ports to England.</p> + +<p><span class='pagenum'><a name="Page_338" id="Page_338">[Pg 338]</a></span>"Furnished by the agent of the North German Lloyd's with letters of +introduction to cattle dealers in London, and with the necessary funds, +we left Nordenhamm in the steamer <i>Schwan</i>, Captain Christensen, at 4 +<span class="smcap">P.M.</span>, on the 10th instant. The vessel carried 347 head of large +cattle, 2 calves, and 260 sheep. Favoured by very fine weather, we +arrived in the Thames at 2 <span class="smcap">P.M.</span>, on the 12th. At the beginning +of the voyage the animals were rather uneasy, trampled a good deal, and +caused considerable motion in the ship; after a time, however, they +became quiet. A sharp, penetrating smell was easily perceptible in the +'tween decks of the ship, which was quickly removed upon a light breeze +springing up, by means of the excellent ventilation and numerous +air-pipes and wind shafts. The animals were several times watered, and +it was easy to see how greatly they were refreshed. The hay in the +racks, on the other hand, was hardly touched.</p> + +<p>"Upon arriving in the port we were introduced by the captain to the two +veterinary surgeons stationed here to inspect the cattle, and witnessed +the rapid disembarkation of the cargo, all of which were thoroughly +healthy, not one being condemned. The cattle, when landed, were +immediately brought to carts standing in readiness and transported to +London, where they are cleansed and then driven into the adjacent +fields.</p> + +<p>"After doing all in our power to attain the object of our journey, we +went back to the port to wait for the <i>Schwan</i>, having first thoroughly +cleansed the clothes we had worn during our inspection of the <span class='pagenum'><a name="Page_339" id="Page_339">[Pg 339]</a></span>diseased +cattle. The <i>Schwan</i> came in shortly after our arrival, and disembarked +256 head of large cattle, 12 calves and 400 sheep, all in good +condition. Mr. Philipps, the London agent of the North German Lloyd's, +was on the spot, together with several reporters from newspapers, who +wished to see by personal investigation how and in what condition cattle +are brought from the Weser.</p> + +<p>"We re-embarked on the <i>Schwan</i> upon the 19th. The crew were engaged +during the voyage in carefully cleansing the ship. The weather was fine, +and we arrived safely at Nordenhamm upon the 21st.</p> + +<p class="right"> +(Signed) "<span class="smcap">G. J. Rippen</span>,<br /> +"Veterinary Surgeon at Seefield.<br /> +<br /> +"<span class="smcap"> H. Fasting</span>,<br /> +"Veterinary Surgeon at Schwey."</p> +<br /> + +<p class="cen"><span class="smcap">Note B.</span><a name="Note_B" id="Note_B"></a></p> + +<p>Professor Simonds having had such opportunities of investigating those +diseases as they existed in England and in foreign countries as were +possessed only by a few Englishmen, might be permitted to offer a few +observations. He had been appointed by the Royal Agricultural Societies +of England and Ireland to proceed to the Continent in 1857, when there +was a rumour that the disease which existed among cattle in this country +at the present time was prevailing in Mecklenburg. Consuls sent +despatches that the rinderpest was prevailing largely, and the +Government, as a precautionary measure, closed the ports against the +introduction of cattle from the Baltic to this <span class='pagenum'><a name="Page_340" id="Page_340">[Pg 340]</a></span>country. He found, +however, from his observations abroad that since 1817 there had been no +disease of this kind westward of a line between Revel in the Baltic and +the Gulf of Venice, but to the eastward of that line it had existed. He +came up with the affection at the Carpathian mountains, where it was +raging in 1857 just as it is raging in England at the present time. Not +only had it existed there, but it had been carried into the interior of +Russia in the ordinary method of the cattle trade. A person who was in +the habit of purchasing cattle attended a fair and bought a number of +animals, and took them to his own farm, and in the course of ten days +one or two were seized with the disease, and the result was there was a +gradual spread of the evil in that district. It gained ground until the +Government instituted the sanitary police regulations, which, though +they were such as would be considered strange in England, were, he +believed, absolutely necessary for the extirpation of the plague. It was +undoubtedly true that no foreign animals had been seized at our ports or +in the metropolitan market; but it was not necessary for the case they +had in hand to say whether the disease was or was not of foreign +importation. There was this fact before them, that it was not until the +month of June that the disease appeared in England. A certain number of +animals came out of a diseased district. He had documentary evidence +that animals came from Revel and came from the district of Esthonia. He +had before him proof that the disease now in England was raging in that +district. They had proof that shortly after the arrival of those cattle +in England the disease manifested itself <span class='pagenum'><a name="Page_341" id="Page_341">[Pg 341]</a></span>here. He admitted there were +difficulties in the way of checking the importation of foreign cattle. +The Government had its eyes open to the matter, and he did not think it +possible for the Government to have done more than they had done or to +have done more quickly what they had been doing. At this moment half the +supply of the metropolitan market came from foreign countries, and he +did not wish to convey any reflection by saying that this disease had +its origin from abroad. He would admit that the animals from Germany and +Hungary were coming in a healthy condition; but he could not admit that +they came from Russia, Poland, or Galicia in so perfect a condition, +because the regulations there were not sufficient to stamp out the +disease. The Government had made an inquiry as to the general health of +cattle on the Continent. They believed France, Belgium, Holland, +Schleswig-Holstein, Oldenburg, and a large part of the Continent that +supplied cattle to this country were free from disease. This went to +show that we had admitted a disease not from where we received our +supplies of meat, but from some other district. Then it must be +associated with the fact that it came into this country when animals +arrived here from an infected district in Russia. Animals from Germany +and Hungary were often shipped and mixed with others from a diseased +district. As regarded the disease being spontaneous, we had been free +from it for twenty years. What was the state of our cowsheds fifty years +ago? Were they not in a more filthy condition than they are now? If, +therefore, the disease had been induced from common causes it would have +been here years and years ago. <span class='pagenum'><a name="Page_342" id="Page_342">[Pg 342]</a></span>It was no reflection to say that a great +many cases could be traced directly to the metropolitan market. Take one +case which occurred in Sussex. Certain cattle had been bought in the +metropolitan market and were taken home. In three or four days they were +ill, and presented symptoms of this affection. In a few days more the +cows and calves were dead. In another instance calves were bought in +Chichester Market, where they had been taken from London. The result was +the death of twelve cows and ten calves. The people had other cattle on +the same farm, and not one of them took it. He could say, too, that +persons who had only one animal had lost it by the disease. How had the +disease got into Norfolk and Kent but by the animals which went from the +metropolitan market? He could prove by documentary evidence that it was +so. He could show there was not a single instance where the origin of +the disease could not be traced to the metropolis. It was the most +fearful visitation that had ever been seen in England. They had adopted +a system of compensation in Norfolk, and if by this meeting something +was done to shut out the animals of infected districts, no doubt the +promoters would receive not only the thanks of London, but the country +generally.</p> + +<p>Mr. Gibbins—Now, if the disease came from abroad, and diseased cattle +were shipped on the other side of the sea, no doubt the voyage would +concentrate and aggravate the disease. The Government inspectors +reported, however, that not one instance had been seen of foreign cattle +so diseased, nor had any been seized and destroyed in London or anywhere +else. Whether <span class='pagenum'><a name="Page_343" id="Page_343">[Pg 343]</a></span>the disease came from abroad or elsewhere he was not able +to state. Sir George Grey asked him whether he had found any disease +among the foreign cattle that came into the market. He said not one. +They had, no doubt, many instances of the disease amongst the cows that +were ordinarily called milch cows, but that were not milch cows when +they came to market, because one effect of the disease was to deprive +the animal of milk. These were then sent to the market and sold as fat +stock. He could only say they had had no cases, except in cows, whether +they came from the dairies in London or elsewhere.</p> +<br /> + +<p class="cen"><span class="smcap">Note C.</span><a name="Note_C" id="Note_C"></a></p> + +<p>M. Dembinski, Professor of Analytical Chemistry and Natural Science, had +also addressed a communication to the Lord Mayor on the subject. The +prevalent Rinderpest, he said, originated in the steppes of Podolia, +from which considerable herds of cattle were exported through the +steppes to Moscow, St. Petersburg, Riga, and Revel, and thence to the +ports of Memel, Königsberg, Dantzic, Hamburg, Kiel, and the Hague. +<i>Deprived of congenial food and pure water on their transport through +the steppes, and then arriving at marshy lands, the exhausted animals +drank the stagnant water, which, during hot weather, exhaled a +pestiferous malaria, and infected them with a predisposition to the +epidemic in question, which developed itself into a kind of fever on the +voyage to England in a crowded condition.</i></p> +<br /> + +<p class="cen"><span class="smcap">Note D.</span><a name="Note_D" id="Note_D"></a><span class='pagenum'><a name="Page_344" id="Page_344">[Pg 344]</a></span></p> + +<p class="right"> +<span class="smcap">International Veterinary Congress, Vienna</span>,<br /> +August, 1865.</p> + +<p>With regard to the cattle plague, it may be well to state that Austria +has been most unfortunately situated, from the readiness with which +Russian cattle have been admitted into the country at various parts of +the western and southern frontiers. At the opening of the Congress this +difficulty was particularly noted by the Ministerial counsellor, Dr. +Vell, who attended on behalf of the Government, for the purpose of +welcoming the assembly, and giving an assurance that its deliberations +would meet with all the attention they deserved. He specially referred +to the fact that the laws relating to cattle disease prevention had been +entirely revised in 1850, but that the Steppe murrain continued to be +introduced by smuggled stock into the western and southern provinces of +the State. It was therefore necessary to attempt a more effectual +control over the propagation of so disastrous a malady.</p> + +<p>Herr Pabst welcomed the meeting on behalf of the Minister of Trade. He +said that the value of the cattle of the Austrian dominions considerably +exceeded one hundred million pounds sterling (one thousand million +Austrian florins), and that cattle plagues completely put a stop to the +development of that essential branch of agriculture which embraces the +improvement and increase of live stock in a country. He assured the +assembly that all would be done that was possible to improve the +existing state of matters, and <span class='pagenum'><a name="Page_345" id="Page_345">[Pg 345]</a></span>that he hoped they would greatly aid the +Government by the discussions which would take place and the conclusions +at which they would arrive.</p> + +<p>I may state, by the way, that an opinion rather generally expressed by +some, and stoutly maintained by others, was that the peculiar +disposition of some of the Austrian subjects, and the feeling existing +in Hungary against State measures, rendered the law, to a great extent, +inoperative. I can, from personal experience, state that although +stringent and most efficient means are used for the suppression of +cattle plagues, and with the best results in Austria proper, there is +great difficulty in carrying out the law in districts where Austrian +rule is at a discount. Indeed this is clearly indicated by the manner in +which the Rinderpest penetrates into Austria, where the laws are similar +to those in the kingdom of Prussia, which is, and has long been, +completely protected from invasions of the disorder.</p> + +<p>At the meeting of the first International Congress, held in Hamburg in +1865, Dr. Röll stated that owing to the length of time to which the +quarantine for Russian cattle extended on the Austrian frontier, herds +of cattle were often smuggled through, and companies had been formed for +the purpose of insurance against seizure by the authorities. The +unlawful traffic was therefore carried on with comparative safety to the +dealers, who cared not what misfortune they brought on a country if only +their personal ends could be served. This question was the first to +occupy the attention of the Congress last week; when a resolution was +proposed to shorten the period of quarantine <span class='pagenum'><a name="Page_346" id="Page_346">[Pg 346]</a></span>for cattle from Russia +into any country from twenty-one days to ten. The discussion was keen. +It was stipulated, however, that the quarantine should be carried out +most strictly over all parts of the frontier, without respect to any +breed of cattle or other circumstances which might be brought forward as +exceptional reasons for retaining animals in quarantine. The committee +appointed to prepare a succinct report on the subject included +Professors Unterberger, Seifmann, Werner, Zlamal, Hertwig, Haubner, and +Röll; and the committee decided in favour of the shortened quarantine, +on the following conditions:—First—When the establishment of +quarantine institutions is effected in accordance with the requirements +of trade and the peculiarities of the frontier, special attention must +be paid to the erection of quarantine stables, &c., where there are +facilities for procuring an abundance of fodder and water. Second—The +animals to be kept under efficient veterinary supervision wherever they +have to submit to quarantine. The inspectors must be properly qualified +veterinary surgeons. Third—The use of a brand to indicate that the +animals have been in quarantine. Fourth—The effectual disinfection, by +washing and otherwise, of animals as they leave the quarantine. +Fifth—The introduction of a poll-tax along the eastern frontiers, and +the appointment of proper veterinarians to be on the watch as to the +health of cattle along the frontiers. Sixth—Careful supervision to be +placed over the traffic in cattle wherever it takes place in a country. +Seventh—The punishment to the full extent that the law allows of <span class='pagenum'><a name="Page_347" id="Page_347">[Pg 347]</a></span>all +who break the rules relating to quarantine or other means for the +prevention of the cattle plague.</p> + +<p>Professor Hertwig, of Berlin, whose opinion is always listened to with +great respect in veterinary circles, stated his reasons for adopting +these resolutions now, whereas in 1863 he was against shortening the +period of quarantine. He referred chiefly to the importance of not +offering temptations for cattle dealers to evade the law by insisting on +unreasonable restrictions. The feeling of the assembly was greatly in +favour of avoiding vexatious and expensive measures, which might greatly +interfere with the employment of capital in cattle traffic. A small +number of professors, not exceeding eight or nine, held out for a +quarantine of twenty-one days.</p> + +<p>It may be as well to state that quarantine regulations, which have been +regarded as almost useless in the prevention of human disorders, from +the great difficulties in the way of carrying them out efficiently, are +recognised as of great value in controlling the propagation of cattle +plagues. It is possible to control the movement of herds, and the +governments of Central Europe have found it absolutely essential so to +do. Indeed, the ablest medical men who have written against the adoption +of a quarantine system for human small-pox and cholera, such as +Professor Siegmund, of Berlin, acknowledge its value and absolute +requirement with regard to the Rinderpest. A professor from Galicia +argued in favour of controlling the movements of people wherever the +disease appeared, and no fact seems to have been better ascertained than +that of the communication of the <span class='pagenum'><a name="Page_348" id="Page_348">[Pg 348]</a></span>Rinderpest from herd to herd by human +beings. Professor Jessen, of Dorpat, states that in Russia the malady +was at one time speedily propagated by the people, who regarded the +destruction of their stock as a visitation of Providence, and who +summoned a priest into their stables to pray with them that the plague +might be stayed. Moving from farm to farm, the malady was by this means +rapidly transmitted. In Hungary, many outbreaks result from people +dressing the carcases and hawking about the meat, which, even where +human beings remain uninjured, is deadly to the cattle whenever the +water with which it is washed is thrown about the yards, or the meat is +hung up near sheds containing living animals.</p> + +<p>The members present at the International Congress spoke in favour of +establishing a fund, apart from the Government grants, for the payment +of diseased or infected animals which have to be slaughtered with a view +to the prevention of the plague. Special precautions were suggested as +to the transmission of articles the product of diseased animals.</p> + +<p>1. Perfectly dried skins, the points of horns cut off, as they often are +for commercial purposes, the salted and dried intestines of cattle, +melted tallow, wools, cowhair, &c., could be freely allowed to pass +unobserved.</p> + +<p>2. Entire horns, hoofs, &c., which are detached from the soft parts, but +which often contain adhering flesh, &c., should be disinfected with +chloride of lime.</p> + +<p>3. As melted tallow is often conveyed in bags which may be charged with +the poison, those bags should be washed with chloride of lime solution.</p> + +<p><span class='pagenum'><a name="Page_349" id="Page_349">[Pg 349]</a></span>4. Fresh bones, fresh skins, and intestines, unmelted tallow, raw flesh, +and fresh sheepskins, should not be sold whenever the Rinderpest exists +in a district.</p> + +<p>According to all the accounts which reach us, the foreign observations +and resolutions may be of essential service in England. The members of +the Assembly were informed by Mr. Erner of the origin and the progress +of the cattle plague in England, and were deeply interested by the +account given of the imminent danger in which many countries are placed +that purchase breeding stock in the British isles. The theories of +spontaneous origin amuse the learned here not a little, as they justly +think we ought not to be so far behind every nation in the possession of +knowledge regarding the propagation of such a disorder as the steppe +murrain.</p> +<br /> + +<p class="cen"><span class="smcap">Note E.</span><a name="Note_E" id="Note_E"></a></p> + +<p>Now, if the disease came from abroad, and diseased cattle were shipped +on the other side of the sea, no doubt the voyage would concentrate and +aggravate the disease. Whether the disease came from abroad or elsewhere +he was not able to state. Sir George Grey asked him whether he had found +any disease among the foreign cattle that came into the market. He had +not one. He could only say they had had no cases, except in cows, +whether they came from the dairies in London or elsewhere. So far as +they knew, not one single bullock or ox had been condemned.—<span class="smcap">Mr. +Gibbins</span>, <i>18th August, Meeting at the Mansion House</i>.</p> + +<p>The very first shed in which the plague must have appeared in London is +a pattern of cleanliness, and <span class='pagenum'><a name="Page_350" id="Page_350">[Pg 350]</a></span>the stock was magnificent, as proved by +the animals in a shed to which the disease has not been propagated. +Almost simultaneously the malady broke out in the Essex marshes, and in +every instance we trace a more or less direct contamination by foreign +stock.</p> +<br /> + +<p class="cen"><span class="smcap">Note F.</span><a name="Note_F" id="Note_F"></a></p> + +<p class="right"> +<span class="smcap">Vienna</span>, August, 1865.</p> + +<p>On the 28th of August about thirty of the members of the Congress +accepted an invitation to visit the renowned agricultural establishment +at Altenburg, in Hungary. After the visitors had inspected the herds and +other appurtenances of this institution, Professor Maasch, its director, +intimated that the Rinderpest had appeared at Nickolsdorf, about four +German miles from Altenburg. The President of the Congress had known +this fact before the party left Vienna for Hungary; but as he feared +some enthusiasts would first see the plague, and then inspect the +Altenburg herds, he preferred to adopt the stratagem of communicating +the information through Professor Maasch, after the great Agricultural +College of Hungary had been viewed. Nickolsdorf, where the steppe +murrain appeared on the 10th of August, is an exquisitely clean village, +with well-whitewashed buildings and broad roads, constituting the centre +of a thriving agricultural district. Its people are typical Hungarians, +not too anxious to work, and, on the whole, poor; but they are +intelligent, notwithstanding the national proclivity to farm a thousand +acres badly rather than one-fourth the quantity to perfection. Their +wants <span class='pagenum'><a name="Page_351" id="Page_351">[Pg 351]</a></span>are not great, and their worldly luxuries, beyond potatoes and +schnaps, are bought with the profits made on large herds of cattle. One +herd only had suffered from the cattle plague when we visited the +village. This herd consisted of 1225 animals, divided into three lots. +The affected portion numbered 450 animals—bullocks intended for work +and slaughter—varying in age from three to seven years. The cows and +heifers had not been smitten. The 450 animals amongst which the disease +appeared were housed in no less than sixteen different sheds in +Nickolsdorf. Out of each of these places sick animals had been taken, +and either slaughtered or permitted to die. We killed four for +dissection on the 29th. Six more had been previously killed, their hides +slacked, and the entire body buried; nine had died, and two we left in +life to be soon slaughtered and disposed of as the others. The district +veterinary surgeon in constant attendance was an extremely active and +intelligent man, who recognised the disease on its first outbreak, and +adopted such measures for separation, destruction, and burial, as +prevented the disease from spreading so rapidly as it has in England.</p> + +<p>The cause of the outbreak was the intermingling of cattle-dealers' stock +with the Nickolsdorf herd; and although the animals which carried it +have not been fully traced, they are believed to have been owned by a +butcher who had purchased them in Comorn, where the malady is raging. +Singular variations have been seen in the symptoms exhibited, especially +when animals are first affected. During the Nickolsdorf outbreak there +has been an invariable incubation of five or six <span class='pagenum'><a name="Page_352" id="Page_352">[Pg 352]</a></span>days; then furor or +delirium appears: the bullocks stare, roar, stamp with their feet, are +prepared to attack people who approach them, and seem to be dizzy at +intervals. They shiver, their muscles twitch, the eyes soon begin to +discharge, and the mucus which flows from the mouth foams. The pulse is +at first slower than usual, until all the fever symptoms appear. There +is more constipation than diarrhœa, though, on examination, the +mucous membranes are all found to be affected precisely in the manner so +often observed in England during the present outbreak. The differences +in the symptoms are accounted for by peculiarities of breed, the +condition of stalls, the food the animals have lived on, and similar +circumstances. We may hear more of these Hungarian outbreaks, but the +chances are we shall not witness in any part of Austria the wholesale +devastation now going on in Great Britain.—<i>International Veterinary +Congress.</i></p> +<br /> + +<p class="cen"><span class="smcap">Note G.</span><a name="Note_G" id="Note_G"></a></p> + +<p>At present the cowkeepers send off the infected beasts to the market, or +to some slaughter-house, where they might be killed. There was believed +to be great danger in allowing the infected cows to be driven through +the streets. If the good could be separated from the bad animals, and if +the latter could be conveyed to sanitoriums, where the medical men could +operate upon them, then much benefit would result; and then, too, if the +animals died, they would be buried on the spot. All the professors were +agreed in this, that if a compensation fund were raised, and <span class='pagenum'><a name="Page_353" id="Page_353">[Pg 353]</a></span>the +cowkeeper were told that he would be remunerated for his loss, he would +at once inform the authorities when the disease made its appearance in +his cowshed. Shed after shed was being now shut up, and men and women +who seemed to be affluent one day were the next reduced to ruin. An +illustration of this would suffice. One day last week a cowkeeper at +Pimlico had 70 or 80 healthy cows. On Wednesday three of them were found +dead. On Thursday 42 of them were sent to the market. Of these 42 three +showed symptoms of the disease, and then the whole of the 42 beasts had +to be slaughtered because of the disease being among the three. The poor +fellow was thus ruined. Last Monday he sent nine more cows to the +market, and these also had to be slaughtered. At present the man was +absolutely out of his mind. Out of his 70 beasts, he had not one left. +Some persons were saying that the disease arose from bad water, bad +ventilation, and bad cowsheds; but in the case of Miss Burdett Coutts, +who had had 40 head of cattle, which were most carefully housed and +attended to—particularly from the moment she heard that the disease was +amongst them—all were gone, with the exception of one cow; so that, +whether it was a want of water or a want of ventilation which in other +cases caused it, this was an instance in which everything was done that +could be done, and yet the plague raged and the mortality +ensued.—<span class="smcap">Mr. Gibbins</span>, <i>Meeting at the Mansion House</i>.</p> +<br /> + +<p class="cen"><span class="smcap">Note J.</span><a name="Note_J" id="Note_J"></a><span class='pagenum'><a name="Page_354" id="Page_354">[Pg 354]</a></span></p> + +<p>Yesterday morning Dr. Jarvis, medical officer of St. Matthew's, +Bethnal-green, received information that Mr. Castell, an extensive +purveyor of milk, had lost eighty-four cows during the past week. Other +cowkeepers in this district have also experienced great losses. The +disease has manifested itself with more or less virulence at St. Anne's, +Limehouse; St. John, Hackney: St. Mary-le-Bow, St. George's-in-the-East, +St. John, Wapping; Christ Church, Spitalfields; St. Leonard's, +Shoreditch; St. Mary, Whitechapel; St. Paul's, Shadwell; the hamlet of +Ratcliff, Stoke Newington, Kingsland, and Tottenham.</p> + +<p>Mr. Gibbins, chairman of the Metropolitan Markets Committee, Mr. Rudkin, +a member of the committee, Mr. Tegg, veterinary surgeon to the market, +and Mr. Baldry, clerk to the market, applied to the sitting magistrate +at Clerkenwell Police Court yesterday for summonses against cowkeepers +for sending diseased cows into the market. During the course of the +present week no less than nineteen cows had been seized in the market +and fairs and condemned. The order was asked for under the 8th section +of the recent Order in Council, which recited that it shall not be +lawful to send or bring to any fair or market, or to send or carry by +any railway, or by any ship or vessel coastwise, or to place upon or to +drive along any highway, or the sides thereof, any animal labouring +under disease. The cattle seized had not been examined by a Government +inspector, and no certificate <span class='pagenum'><a name="Page_355" id="Page_355">[Pg 355]</a></span>had been given to the owners that they +were fit to be removed. The market authorities wished it to be known +that proceedings would be taken in every case that was brought under +their notice. Mr. Cooke observed that the inspectors had power to seize +and slaughter, or cause to be slaughtered, and to be buried in any +convenient place, any animal labouring under the disease. Had that been +done? Mr. Tegg said that the animals were in some of the cases +slaughtered, and the others would be slaughtered in the course of the +day. The summonses were granted.</p> + +<p>Yesterday, the summonses issued at the instance of Mr. Frederick Thomas +Stanley, a member of the Royal College of Veterinary Surgeons, and one +of the inspectors appointed under the Order in Council, came on for +hearing before Mr. Burcham, magistrate at the Southwark police court. +The summons in the first case was addressed to Thomas Meredith, of the +Flying Horse-yard, Blackman-street, for that the defendant, without the +licence of the said inspector, did unlawfully remove from his premises +some animals labouring under the cattle disease. Mr. Sleigh, instructed +by Mr. Gant, appeared to support the summons; and Mr. W. Edwin for the +defendant. Evidence was given that the defendant had been warned that +the cows were diseased, but that he had removed them notwithstanding. +The further hearing of the case was adjourned, as were also the other +summonses of a like nature.</p> + +<p>In pursuance of powers vested in him by the Manx Legislature, the +governor of the Isle of Man has issued a proclamation prohibiting the +importation of <span class='pagenum'><a name="Page_356" id="Page_356">[Pg 356]</a></span>cattle into the island. Tinder the same Act his +Excellency has power to subject all cattle imported into the island to a +five days' quarantine.</p> +<br /> + +<p class="cen"><span class="smcap">Note K.</span><a name="Note_K" id="Note_K"></a></p> + +<p>Tracing, as we have done, the sale of infected stock from abroad as far +back as the 19th of June, we find that each week that the disease has +been amongst us a fresh county has been contaminated; and more than that +when we consider that Scotland has not escaped.</p> +<br /> + +<p class="cen"><span class="smcap">Note L.</span><a name="Note_L" id="Note_L"></a></p> + +<p><span class="smcap">Scotland.</span>—The cattle plague has travelled North to +Aberdeenshire, and has killed a number of animals almost simultaneously +on three farms at many miles distance from one another. The owners of +stock in one of the districts, and the Royal Northern Agricultural +Association, are taking, or resolving to take, sharp and prompt steps to +stay the progress of the disease. The committee of the association +having met on Friday, appointed a committee of inspection, arranged for +a public meeting of persons interested, and favourably entertained the +notion of forming a fund for mutual insurance against the sacrifices and +losses which the extension of the disease might occasion. A meeting of +the General Central Union was also held at Stirling on Friday, and a +committee was appointed to confer on the subject with the directors of +the Highland Society, and report to another meeting to be held next +Friday.—<i>Scotsman.</i></p> + +<p><span class='pagenum'><a name="Page_357" id="Page_357">[Pg 357]</a></span>The most important communication received to-day is from Scotland. The +malady has undoubtedly broken out near Kelso, on fourteen head of cattle +imported into London and sent north. Twenty-eight animals have been +seized with the disease at Woolwich, and calves from the London market +are said to have taken the malady down to Horsham and Grinstead.</p> + +<p>Information has been received concerning the sale of at least fifty-four +diseased and infected animals in the Metropolitan Cattle Market the 3rd +instant.</p> +<br /> + +<p class="cen"><span class="smcap">Note M.</span><a name="Note_M" id="Note_M"></a></p> + +<p>Mr. Charles Panter has, at the request of Earl Granville, drawn up a +statement relative to the health of the cows on a farm hired by his +lordship at Golder's-green, on the Finchley-road. In publishing the +statement, Earl Granville says: "When I left England, a month ago, there +were about 130 milch cows in four sheds. In the two largest and best +managed I found only one cow yesterday (Sept. 4). His Royal Highness the +Duke of Coburg informed me last week that what he believed to be the +same disease visited Coburg last year. No one could trace its origin, +and no medical treatment was successful. Air and water were their only +remedies. Some men had died from eating the meat killed at a particular +stage of the disease. His Royal Highness had seen a horse die in four +hours, killed by flies which came from the carcase of a cow which had +been allowed to remain above ground. The disease disappeared in the +autumn as mysteriously as it had come. I understand that <span class='pagenum'><a name="Page_358" id="Page_358">[Pg 358]</a></span>Professor +Simonds is of opinion that the disease mentioned by the Duke of Coburg +is not the same as that from which we are suffering here—that its name +is the Siberian Pest." Mr. Panter's statement is dated Sept. 4, and is +as follows:—"On the 13th of July I purchased five Dutch cows in the +Metropolitan Market, and placed them in quarantine at Child's-hill Farm, +one mile from here. On the 22nd of July one of them showed signs of +debility; diarrhœa followed. Thinking it was only a cold, she was +treated accordingly, but continued to get worse, and died in five days. +Two more were attacked in a similar way, when veterinary advice was +called in, but in five days the whole either died or were slaughtered. +Every precaution was used to prevent the spread of infection here; the +men who attended the sick cattle were not allowed to go among the +healthy ones, and <i>vice versâ</i>. But, previous to this, bearing of the +disease in the London cowsheds, I adopted precautionary measures, such +as a liberal use daily of chloride of lime, administered one ounce of +nitre in half a pint of water to each cow, and a small quantity of tar, +and painted their noses with tar. But on the 8th of August, +unfortunately, the disease showed itself here in a fat cow that had been +for ten months in the best built, best drained and ventilated shed. No +new stock had been added for nine weeks. In a few hours four more cows +showed symptoms of it. I immediately had them all removed and +slaughtered, and made a <i>post-mortem</i> examination of them, and found the +windpipe in a state of decomposition, the lungs inflated, the small +intestines red and inflamed, and the meat of a dark <span class='pagenum'><a name="Page_359" id="Page_359">[Pg 359]</a></span>yellow colour +outside, and dark red inside, which I think unfit for human food after +the first stage. The disease confined itself to the above shed of +forty-eight cows (which are now all gone) till the 20th of August, when +it broke out in another shed of thirty-five cows, some ten yards from +the former one, and continued its ravages, taking from two to four cows +daily, till they are all gone but two, one of which has not been +attacked; the other, which was a bad case, is cured, and partly come to +her milk again. On the first symptoms I had her separated from the other +stock, and did not treat her for two days, when diarrhœa set in; I +then gave her a bottle of brandy and four ounces of ground ginger in +three quarts of old ale. She lay in a kind of stupor for twelve hours, +when I could see a change in her for the better. I continued to give her +daily four quarts of gruel made with old ale and two ounces of ginger. +In four days she was sufficiently recovered to eat a little hay, &c., +and do without further treatment. In another case the above treatment +failed, and the animal died in three days. In other cases I allowed +anyone to treat them who thought they had a remedy, both professional +men and others. One persevering young veterinary surgeon came up out of +Somersetshire and treated two cases most energetically, but failed in +both; one died in four, and the other in eight days. In other cases +tonics, stimulants, blisters, and setons have been tried, but all +failed. The whole of the eighty-one cows lost were of the English breed; +we have not as yet had any loss out of the other two sheds, consisting +of about half English and half Dutch cows, and standing about forty +yards from the infected <span class='pagenum'><a name="Page_360" id="Page_360">[Pg 360]</a></span>shed. It may be interesting for your lordship +to know that I had the shed at Child's-hill Farm immediately cleansed +with disinfectants, and washed with hot lime, &c., and bought twelve +fresh cows and placed them there on the 16th, which are now in perfect +health; and a neighbour situated midway between here and that farm had +twenty-three cows lying in a field; the plague took twenty of them, and +in three weeks he replaced them with new stock, which are still healthy, +he having had them a month. Another neighbour, a mile distant, had a +fine herd of seventy-two cows (English) lying in the fields a fortnight +ago. The plague broke out among them, and now he has only eight left in +health. From my own experience, and from all I can learn, I believe the +disease is atmospheric, and of a typhoid character. The first symptom in +a milking cow is an almost entire loss of milk, then loss of appetite, a +watery discharge from the eyes, nostrils, and mouth, which thickens as +the disease develops itself; rumination ceases, her ears hang down, her +eyes are heavy and sunken, bloody matter is seen in the excrement, great +debility is seen, diarrhœa sets in, and death takes place in from +three to nine days. I have read of iron water being a preventive of the +disease. All the water your cows have drunk comes six miles through +rusty iron pipes."</p> +<br /> + +<p class="cen"><span class="smcap">Note N.</span><a name="Note_N" id="Note_N"></a></p> + +<p><span class="smcap">The Cattle Murrain at Holly Lodge.</span>—On the 27th of June an +Alderney bull was purchased at Bushey, near Watford, and placed with the +rest <span class='pagenum'><a name="Page_361" id="Page_361">[Pg 361]</a></span>of the herd, then consisting of eleven cows, five sucking calves, +three yearling heifers, and one bull. The bull had been imported from +Alderney for several months. About a month after—namely, on the 29th of +July—a cow in calf was attacked with unusual symptoms. She was +separated from the rest; nourishing drinks were administered; but having +calved, she died forty-eight hours after the first symptoms were +observed. This led to the belief that she died of the disease which then +began to prevail. This cow had been pastured with the others in a field +occasionally used for grazing sheep that were taken to the Metropolitan +Cattle-market, and, if not sold, brought back again until the next +market day; the sheep were separated from the cows by iron hurdles. The +Holly Lodge Estate is partly bounded on the east by the route taken by +drovers with foreign and other cattle to and from the market, some of +which are also occasionally brought back to neighbouring fields. The +high road forms the western boundary within a few yards of the +cattle-sheds and pastures. These facts are stated to show that the +contagion might have been easily communicated to the animals. A few days +later three calves were attacked with cold shivering and twitching of +the muscles. The previous nights having become suddenly and unusually +cold and wet, the symptoms were at first attributed to that cause. +Although these calves had been pastured quite apart from the cow which +first died, the cow had been driven across the field where the calves +lay to the shed in which it died, the calves having been placed in the +next shed, where two of them died on the 6th <span class='pagenum'><a name="Page_362" id="Page_362">[Pg 362]</a></span>of August, unmistakeably +of the cattle plague. The third calf was sent to the Royal Veterinary +College, where it also died. By the 9th of August four cows and the bull +were seized with the disease so virulently that it was thought necessary +to kill them after three days' illness. On the 12th a cow and a heifer +were also destroyed, and on the 14th one of the sucking calves died. +Thus, out of a herd of nineteen animals, twelve had died within a +fortnight. The malady had taken so strong and sudden a hold upon them +that no systematic means of remedy could be applied except separation, +warmth, stimulants, and the medicines ordinarily given in cases of cold +and fever. On the 13th of August two more cows were pronounced incurable +by two of the veterinary surgeons who had been called in; but it was +determined, upon further advice, to try a mode of treatment upon them +not hitherto adopted. One drachm of calomel was administered in gruel, +four hours afterwards one pint of castor oil, and three hours later one +quart of yeast. About two quarts of warm porter were added to a gruel of +yeast and oatmeal, and given at intervals. These remedies acted most +efficiently, and in one case gave much encouragement. The next day the +cow began to eat hay, to chew her cud, and to yield a good quantity of +milk. These remedies, together with bi-sulphate of soda, which +invariably produced a return of the milk, and quinine, were then tried +upon four other patients, with varied success. But in the end all these +cows died, not, it is believed, of the cattle murrain, but of exhaustion +occasioned by the activity of the drugs administered to them. This +<span class='pagenum'><a name="Page_363" id="Page_363">[Pg 363]</a></span>belief was strengthened by the healthy appearance presented by the +viscera of the first cow thus experimented upon, on its being partially +dissected after death. The remaining cow thus treated is still alive. It +is impossible to avoid believing that had the medical man who kindly +gave his attention to these animals, been better acquainted with the +constitution of the creature, or had those who tended them had any +knowledge of medicine, three of the cows treated in this manner might +and probably would have recovered; and even when the animals succumbed +the consequences were less serious, the virulence of the poison being +expelled—at least it was undiscernible to those who dissected them. +During the fortnight that the murrain was raging, one cow in calf and +one calf remained perfectly healthy, apparently, until both were seized +within a day of each other; these had always been kept separate from the +sick animals, and tended by other men. The calf died, and the cow was +destroyed, in consequence of the symptoms being so violent. In this case +very little calomel was given. As it may be as well to mention all +particulars, it may be stated here that the men who tended the animals +were provided with a dress, and that it was found desirable that a +certain quantity of stimulants—brandy, coffee, and strong soup—should +be given to prevent nausea and other uncomfortable feelings from which +the men suffered. All the directions respecting the burying of the +animals issued by the Privy Council have been strictly complied with; +clothes, &c., have been burnt, chloride of lime (Macdougall's +disinfectant) was used with others <span class='pagenum'><a name="Page_364" id="Page_364">[Pg 364]</a></span>to destroy insects and flies, with +abundance of white-washing. The men were recommended to use, as a wash +for the mouth, manganate of potash. The first crop of grass in the field +where the cattle lay before their sickness, and during it, has been +destroyed also; and it is intended to use some disinfectant, such as +charcoal or lime, to spread over the field. Miss B. C. feels so +persuaded that some mode of treatment could be found to alleviate, if +not to save life, that she has determined to employ a medical gentleman, +who kindly offers his services, and to take also the advice of a good +cow or veterinary surgeon, and to try the effects of various remedies in +some of the cowsheds where persons will be glad to let such experiments +be tried; and it is also her intention to ask the Privy Council to allow +one of the Government Inspectors to assist and report upon the cases. It +may not be altogether unimportant to add that the state of the +atmosphere seemed to have some effect upon the health of the animals, as +upon those occasions the symptoms were most severe during the +thunder-storms which then occurred. The milk which returned was found to +be rather watery, and the cream had a peculiar appearance. At first the +pigs declined it, and it was not thought advisable to continue to give +it at all to any animals for about a week. It is now perfectly good.</p> +<br /> + +<p class="cen"><span class="smcap">Note O.</span><a name="Note_O" id="Note_O"></a></p> + +<p>Advices from Holland, dated the Hague, Sept. 6, state: "The cattle +disease has now been observed <span class='pagenum'><a name="Page_365" id="Page_365">[Pg 365]</a></span>in the parishes of Kethel, Delfshaven, +Moordrecht, Uaardingen, Averschie, Kvalingen, Nieuwerkerk on the Issel +(two hours from Rotterdam), Spykenisse, Schiedam, Herrjansdam, Maasland, +Sommelsdyk, and Zevenhuisen. It has spread most at Kethel, where it +first broke out among a cargo of cattle not admitted into England. In +the other parishes some sixty animals were infected on the 1st inst. The +post-mortem examination of the diseased beasts presents the abnormal +appearances that have been found in the disease elsewhere, <i>i.e.</i>, +swollen mucous membranes with red spots, peculiar exudations in the +fourth stomach and intestines, &c. The medical commission declares the +malady to be the <i>typhus contagiosus bovum</i> of modern veterinary +surgery, and recommends that infected animals should be treated with +from three to four drachms of muriatic acid, mixed with six ounces of +treacle and decoction of linseed. Decoctions of Peruvian bark and osier +peelings, with sulphuric ether, are also said to be beneficial to weak +animals. The avoidance of all contact of the cattle-tenders with +infected beasts is especially enjoined, and ventilation and cleanliness +of the stalls strongly recommended. Cattle markets and fairs are +suspended until further orders, and extraordinary measures for +disinfection are applied upon steamboats and railways."</p> +<br /> + +<p class="cen"><span class="smcap">Note P.</span><a name="Note_P" id="Note_P"></a></p> + +<p>The following document has been received at the Foreign Office from her +Majesty's Agent and Consul-General at Bucharest:—</p> + +<p class="cen"><span class='pagenum'><a name="Page_366" id="Page_366">[Pg 366]</a></span>(<i>Translation from the Official "Monitoral," No. 173, August 8-20, +1865.</i>)</p> + +<p class="cen"><span class="smcap">General Direction of the Sanitary Service.</span></p> + +<p>From the 1st to the 15th July a typhus epizooty broke out among the +large horned cattle in the districts of Ilfov, Jassy, Bolgrad, Falcin, +Buzeo, and Roman, which still continues, but is on the decrease. The +Direction, in consequence, publishes the above for the information of +those concerned.</p> + +<p class="right"> +<span style="padding-right: 8em">The Director-General,</span><br /> +<span style="padding-right: 3em;">(Signed) <span class="smcap">D. Gluch</span>.</span></p> +<p class="noin"><span style="margin-left: 1em;">Aug. 2-14, 1865.</span> +</p> +<br /> + +<p class="cen"><span class="smcap">Note R.</span><a name="Note_R" id="Note_R"></a></p> + +<p class="right">August 14.</p> + +<p><span class="smcap">The Question of Infection.</span>—Yesterday afternoon Mr. Alfred +Ebsworth, of 11, Trinity-street, Southwark, the medical officer of +health for the parish of St. Mary, Newington, attended before the +sitting magistrate to make a statement with regard to the condition of +the parish from the influx of diseased cattle, and the manner in which +they were disposed of. Addressing the magistrate (Mr. Burnham) Mr. +Ebsworth said that on that morning he, in his capacity of medical +officer of health for the parish of St. Mary, Newington, received an +order to attend professionally a man who was seriously ill in +Kent-street, within the parish. While paying the visit to the patient +his attention had been drawn to the condition of a slaughter-house on +the other side of the street, where <span class='pagenum'><a name="Page_367" id="Page_367">[Pg 367]</a></span>it was reported to him there were +fifteen cows which had been ordered by the Government officer to be +destroyed at the Bricklayers' Arms Station, and then to be buried. The +animals were accordingly destroyed by the men in the employ of Mr. +George Nicholls, the proprietor of the yard in question; and from Mr. +Nicholls he had learned that, instead of the carcases of the animals +being buried, they were carted through the parish of St. George's to +Mitcham, where they were boiled down, and brought back through the +parish of St. Mary, Newington, in the shape of cats'-meat. He (Mr. +Ebsworth) felt it his duty to come before the magistrate with this +complaint, especially when the cattle plague was so prevalent. He had a +right to inquire upon what grounds the carcases had not been disposed of +on the spot where they had been slaughtered, instead of being carted +through the parish he represented, in a way calculated to spread the +infection. He could not but regard this as a most iniquitous proceeding, +and he attended with a view to prevent a repetition of the practice. Mr. +Frederick T. Stanley presented himself, and said that he was a member of +the Royal College of Veterinary Surgeons. He had been appointed an +inspector of cattle under the orders issued by the Privy Council. Within +the district there were no means of burying the carcases of the diseased +and condemned animals, and in the instance referred to they could not +have been buried in the cowshed. It was impossible to bury the carcases +in the London districts, and hence they were sent to the knacker's yard, +where it was supposed they would be disposed of. Mr. Ebsworth: <span class='pagenum'><a name="Page_368" id="Page_368">[Pg 368]</a></span>And +that, your worship, is what I complain of. Mr. Burcham: You think that +the practice to which you have called my attention is calculated to +propagate the extension of the disease. Mr. Stanley declared that the +skins were disinfected under his especial orders. Mr. Burcham remarked +that the animals had been taken to the slaughter-house, not for the +purpose of being killed and buried, but that their skins should be taken +off and disinfected. Why should they have been taken to Mitcham? Mr. +Stanley stated that the disease could not be communicated from a dead +animal, and it was conveyed only by inoculation, or through the breath +of a living animal upon the dead body of a diseased ox. Mr. Burcham: I +do not agree with you in that opinion. I believe that infection may be +conveyed by a dead animal. Mr. Ebsworth said that such was his opinion, +and, having regard to 28,000 patients in the parish, he had felt it his +bounden duty to come forward to make this complaint. He thought such +things ought not to occur. Mr. Burcham was of the same opinion, and that +such a commodity ought not to be allowed to be conveyed through the +public streets in open carts. Just before the magistrate was about to +rise, Mr. Stanley introduced to his worship Professor Simonds, and a +long colloquy (in private) ensued between them. At its close Professor +Simonds retired, and Mr. Burcham said: I wish to state that I wanted to +be satisfied that everything was done by Mr. Stanley that could be done +under the circumstances by which he was surrounded, in the midst of +great difficulty. I have had an interview with Professor Simonds, and he +informs me <span class='pagenum'><a name="Page_369" id="Page_369">[Pg 369]</a></span>that there are the greatest difficulties, if not +impossibilities, in finding any places near London in which the dead +carcases of diseased animals can be buried. In the case now before me +these animals were slaughtered at the Bricklayers' Arms Station, and +were then taken to the slaughter-house in Kent-street, under the notion +that the owner of the slaughter-house had the means of boiling them +down. It appears that he had no such apparatus, and hence he found it +necessary to send the carcases to Mitcham, the nearest place at which he +believed the carcases could be buried and disposed of, and the +neighbourhood thereby disinfected. Professor Simonds is perfectly sure +that this meat when boiled down cannot by any probability cause the +infection to spread. It was possible, but not probable, that infection +might be introduced by the carcases of the diseased animals on their way +to the place where they had to be boiled down; but it appears to me, +from what I have just heard, that every precaution has been taken to +prevent such an occurrence. It seems that the authorities cannot find a +place within a reasonable distance in which the carcases can be buried, +and, therefore, they are obliged to have recourse to boiling them down, +as the only alternative. It is right that I should add that the conduct +of Mr. Stanley, the inspector, has been quite in conformity with the +directions he has received, not only under the Orders in Council, but +also sanctioned in my presence to-day by Professor Simonds. I trust that +this statement will remove from the mind of Mr. Stanley any unfavourable +impression he may have entertained; and I will only add my opinion, that +<span class='pagenum'><a name="Page_370" id="Page_370">[Pg 370]</a></span>the diseased cattle ought to be removed through these populous +districts in closed and not in open carts. The conversation then closed, +and at an unusually late hour the court adjourned.</p> + +<p><span class="smcap">Diseased Meat.</span>—At the Thames Police Court yesterday Henry +Frost, an old man, was charged with having allowed to be deposited on +the premises occupied by him in the rear of the house, No. 13, +Sidney-street, Stepney, four quarters of beef prepared for sale and +intended for the food of man, but which was unfit for human food. Frost +carried on the business of a greengrocer. He asserted that he let the +place to other men, who were the actual offenders. It was intimated that +the vestry had no disposition to press for a heavy penalty. Mr. Paget +fined the prisoner 40s. At Clerkenwell, Mr. Tegg, inspector at the +Metropolitan Cattle Market for the City authorities applied to Mr. +D'Eyncourt for an order to destroy a quantity of diseased meat which he +purposed seizing. Mr. D'Eyncourt said the meat must be actually seized +and condemned upon evidence before he could make the order. In the +matter of the seizure of 32 quarters of beef, weighing about 3000 lbs., +which was found on the premises of a knacker in Pleasant-grove, +Belle-isle, Mr. D'Eyncourt dismissed an application made against the +defendant under the Nuisances Removal Act. The defence set up was that +the meat was recognised as bad and diseased by the killer as soon as the +animals were slaughtered.</p> +<br /> + +<p class="cen"><span class="smcap">Note S.</span><a name="Note_S" id="Note_S"></a><span class='pagenum'><a name="Page_371" id="Page_371">[Pg 371]</a></span></p> + +<p>The Orders in Council seemed only to complicate the matter, and how +effectually to combat the evil was a most difficult question. Some said +the grand remedy was the knife, and others suggested that the diseased +animals should be sent to a sanatorium. To destroy the diseased cattle +was impossible, except the owner of them or the inspector went round and +obtained an order from a magistrate for their destruction. The last +meeting was adjourned, among other purposes, in order that the committee +might take the opinion of the law officers upon the subject. It so +happened, however, that most of the law officers of the Corporation were +at present out of town. Fortunately the Common Serjeant was found, and +he gave an opinion which confirmed the committee in their view that they +had no power to kill, and no power to do anything except in the matter +of isolation. Then the committee passed a resolution that another +committee ought to be formed to raise the necessary funds for +compensating the cattle-owners, and to see that those funds were +properly applied, for the money was only intended to apply to the cattle +plague, and was not meant to go in the shape of compensation for +pleuro-pneumonia, or for the foot diseases. In other words, they were +now legislating for the cattle plague or Rinderpest only. He resided at +Dulwich, and he found that in the villages adjoining there were many +cows, and never in his life had he seen finer cows. Not one of them had +been affected <span class='pagenum'><a name="Page_372" id="Page_372">[Pg 372]</a></span>by the disease. There was a cowkeeper at Peckham who had +200 cows, and all of them were in the most healthy state. At Brixton +Hill a man had 30 cows in the same excellent condition. At Dulwich +nearly all the cows were diseased, but there the shed and other +accommodation was exceedingly bad. In parts of Peckham Rye some of the +cowkeepers had lost their cattle, but there again the places were badly +ventilated, and the cows were badly cared for. He believed that the +disease might be prevented by the use of proper precautions on the part +of those who had the greatest interest in keeping their cows in a +healthy state. He believed, too, that this question affected the whole +of the metropolitan district quite as much as it did the City itself. +There were no fewer than 106 head of diseased cattle lately seized; but, +as he said before, they could not be killed without an order from a +magistrate, and a magistrate would naturally feel a difficulty in +issuing an order to kill so many as 106 head. It was necessary, under +such circumstances, that a deputation should wait upon the Home +Secretary and ask him to provide a remedy, and tell the authorities what +they were to do at such a crisis. If, as it now appeared, the inspectors +and the markets' committee had been slaughtering beasts without +authority, who was to pay the costs should proceedings against them be +commenced? Professor Simonds seemed to think that next session a bill of +indemnity would be introduced, and certainly something of this kind was +rendered necessary, for cattle were now coming here which were consigned +to A., B., and C., and then the owners could not be <span class='pagenum'><a name="Page_373" id="Page_373">[Pg 373]</a></span>found, and without +the consent of the owners the diseased beasts could not be killed. The +next subject in the report had reference to slaughter-houses. As there +were no places at present to which cattle in an incipient stage of the +disease could be removed from the sheds in which they were placed along +with untainted cattle, it was now proposed that slaughter-houses should +be established in London for their reception. Then came the question, +how were the beasts to be removed from the sheds to the +slaughter-houses? It was the opinion of many that they ought to be +removed in vans, and not driven through the streets; but, however that +might be, slaughter-houses should be erected in the metropolis where the +tainted animals might be killed. Then came the question, how was an +animal to be dealt with when first stricken with the disease? It was +suggested that hospitals or sanatoriums should be provided, to which the +beasts should be sent. But this was a matter of great importance, to +which the attention of the committee to be appointed and that of the +medical men would have to be directed. If the plague went on it would +affect all classes, rich and poor alike, and instead of meat being as +now at a reasonable rate, it would go up 4<i>d.</i> or 6<i>d.</i> per pound; but +he had hopes that the disease might be checked, particularly as +Professors Simonds and Gamgee had been more successful in the treatment +of it than they had previously been.</p> +<br /> + +<p class="cen"><span class="smcap">Note T.</span><a name="Note_T" id="Note_T"></a><span class='pagenum'><a name="Page_374" id="Page_374">[Pg 374]</a></span></p> + +<p class="right">August 31.</p> + +<p><span class="smcap">Deputation to the Home Office.</span>—Yesterday afternoon the Lord +Mayor proceeded from the Mansion House to the Home Office, and had an +interview with Mr. Waddington on the subject of the cattle plague, and +the desirability of establishing hospitals or sanatoriums within the +metropolitan districts for the reception and medical treatment of +diseased cattle. His lordship was accompanied on the occasion by the +following deputation from the Markets and Cattle Plague Committees:—Mr. +Gibbins (Chairman of the Markets Committee), Mr. Webber, Mr. Gower, Mr. +Brewster, Mr. Rudkin, and Dr. Jarvis (the Medical Officer of Health for +Bethnal-green). Sir George Grey having left London for Falloden.</p> + +<p>The Lord Mayor introduced the deputation to Mr. Waddington, and in doing +so, said that their object was to obtain the sanction of Government to +the establishment of hospitals or sanatoriums within the metropolitan +districts, to which diseased cattle could be conveyed from the cowsheds +in order that they might there receive medical treatment, and be, if +possible, restored to health. He observed that similar establishments +had been formed at Edinburgh and other large towns, and that they had +been found to work most satisfactorily, not only in separating the +diseased cattle from those which were non-diseased, but in affording +facilities to the medical profession to exercise their skill and +knowledge under circumstances <span class='pagenum'><a name="Page_375" id="Page_375">[Pg 375]</a></span>more favourable to a fair trial of both +than they could expect to find in crowded cowsheds, many of which were +in a filthy condition and badly ventilated. He pointed out the progress +the plague had made, and was still making, in the metropolis, and how +its effects upon the high price of meat and milk were affecting all +classes of the community. The difficulties, he said, of adequately +meeting the necessities of the case were at present very great, and some +of these consisted in the alleged illegality of slaughtering diseased +animals without an order from a magistrate, and also the illegality of +removing those diseased from the cowsheds to the hospitals, supposing +the latter to exist. But he hoped the Government, who had no doubt well +considered a subject of such vast importance, would speedily do away +with those difficulties, and render the fullest aid to the Markets' +Committee and Metropolitan Cattle Plague Committee, who were unceasingly +devoting their time and attention to mitigate, and, if possible, put an +end to the evil. At present, however, the object of the deputation was +limited to that of obtaining the sanction of the Government to the +establishment of the hospitals or sanatoriums. This was an object which +had not only received the general approval of the two committees +mentioned, but also of the medical profession, and he might add, what it +was by no means unimportant to bear in mind, that the cowkeepers +themselves and the salesmen of the Cattle Market were also in favour of +it.</p> + +<p>Mr. Gibbins and the several members of the deputation corroborated what +had fallen from the Lord <span class='pagenum'><a name="Page_376" id="Page_376">[Pg 376]</a></span>Mayor, and strongly advocated the necessity of +having the hospitals speedily established.</p> + +<p>Mr. Rudkin called the attention of Mr. Waddington to the fact that the +day before there were fourteen diseased cows seized at the +slaughter-house of the Cattle Market, which had been sent there from the +cowsheds of the metropolis. He argued that this in itself was a proof +that the Order in Council, as at present carried out, was insufficient +to prevent diseased cows from being sent from the cowsheds by their +owners to be slaughtered for human food.</p> + +<p>Mr. Waddington, who listened very attentively to the whole of the +statements, said he would take an early opportunity of communicating +with Sir George Grey upon the subject. In the first instance, however, +he wished the deputation to forward to him their views in writing, and +these also would be transmitted to the Home Secretary.</p> + +<p>The deputation promised to comply with the suggestion, and thanked Mr. +Waddington for the courtesy with which he had received and the patience +with which he had listened to them.</p> + +<p><span class="smcap">Yorkshire.</span>—The plague has extended to this district. The cases +reported, however, are extremely few, and precautions are being taken +which it is hoped may stop the further progress of the disease. On +Tuesday a meeting of the Yorkshire Medical Veterinary Society was held +at Leeds, and the question was discussed in all its bearings. It was +stated that four cases had occurred in Leeds, and the disease has also +appeared in the Skyrack division of the Riding. The general result of +the discussion was, that members of <span class='pagenum'><a name="Page_377" id="Page_377">[Pg 377]</a></span>the society were recommended, when +diseased cattle were submitted, not to order them to be killed, but to +place them in a sanatorium for medicinal treatment; the wholesale +destruction of the animals being regarded as a blot upon the profession.</p> +<br /> + +<p class="cen"><span class="smcap">Note V.</span><a name="Note_V" id="Note_V"></a></p> + +<p>Indeed, information has reached us of the disease existing in +Dumfriesshire, but there is some doubt on this point. So long as we hear +of infected, or probably infected, cattle being disseminated in large +numbers from the great markets of the country, we must have the +propagation of the malady. For the welfare of this country, it is deeply +to be regretted that our Government cannot deal with this question as +Continental authorities do. <i>I regret to say some of our neighbours +laugh at our expense.</i> They see us helpless owing to the wretched state +of our laws on the subject, and they are not a little amused at the +theories of spontaneous development of the disease which some still +advocate. The French Emperor has sent over Professor Bouley, who is +still in this country, and who telegraphed on his first arrival, about +ten days ago, that the ports of France should be instantly closed to +British cattle. This has been done, and we may depend upon it the French +people will not suffer as we now must.—<span class="smcap">Gamgee</span>, <i>Lettre du 24 +Août</i>.</p> +<br /> + +<p class="cen"><span class="smcap">Note Y.</span><a name="Note_Y" id="Note_Y"></a></p> + +<p class="right">August 16.</p> + +<p><span class="smcap">More Seizures of Diseased Meat.</span>—Yesterday Mr. Paget, in the +course of the proceedings at the <span class='pagenum'><a name="Page_378" id="Page_378">[Pg 378]</a></span>Thames Police Court, was informed that +there was a large quantity of meat in a van in the police-yard +adjoining, which had been seized that day by Mr. J. Stevens, the +sanitary inspector of Mile-end Old Town, and which was described as +unfit for human food. The inspector stated, that in consequence of +having been informed that there was a quantity of diseased meat at the +shop of Mr. Frost, butcher, Sydney-street, Mile-end Old Town, he went +there that morning, and found four quarters of beef (two fore and two +hind quarters) which were from a diseased beast. He made a seizure of +them, and heard that the animal had been sent by a person of the name of +Stephens, a cowkeeper in business on Bow-common. The meat was in a very +nasty state, and totally unfit for human food. (Mr. Paget went into the +police-yard to examine the meat, which was in a very shocking state.) +Dr. Freeman, Medical Officer of Health of the Hamlet of Mile-end Old +Town, stated that his attention was called to the state of the meat by +the sanitary inspector. He examined it, and gave his opinion that it +should be destroyed, as it was not only in a diseased condition, but he +believed that it had died from some disease. Mr. Paget: Can you state +the nature of the disease which caused its death?—Witness: I cannot. +Most likely it was the prevailing epidemic; and if it were eaten it +would be very injurious. Mr. Paget, after hearing the evidence, ordered +that the meat should be immediately destroyed, when the inspector took +the van with its contents to a knacker's yard to see the order carried +into effect.</p> +<br /> + +<p class="cen"><span class="smcap">Note Z.</span><a name="Note_Z" id="Note_Z"></a><span class='pagenum'><a name="Page_379" id="Page_379">[Pg 379]</a></span></p> + +<p><span class="smcap">Nefarious Attempt to spread the Plague.</span>—Yesterday Mr. Gifford, +Sanitary Inspector to the parish of Paddington, asked (at Marylebone +Police Court) for the magistrate's advice under the following +circumstances:—Applicant said that, in consequence of information +received, he yesterday went to a cowshed situate on the Maryland Farm, +Harrow-road. He found the door fastened. On looking through one of the +chinks, he saw a cow which apparently was in the worst stage of the now +prevailing disease, and his opinion was verified after he had burst open +the door and examined the animal. He subsequently ascertained that the +diseased cow had been brought some distance by a man who was at feud +with the owner of the Maryland Farm, and surreptitiously placed amongst +the healthy cattle. This was the first case where the disease had shown +itself in the parish of Paddington. Mr. Yardley referred the applicant +to the Order in Council, dated the 24th of July, 1865, under which he +thought inspectors of nuisances had power to act summarily.</p> +<br /> + +<h3>THE END.</h3> +<br /> +<br /> +<br /> +<br /> + +<h4>LONDON:<br /> +SAVILL AND EDWARDS, PRINTERS, CHANDOS STREET,<br /> +COVENT GARDEN</h4> +<br /> +<br /> +<br /> +<br /> + +<div class="tr"> +<p class="cen"><a name="TN" id="TN"></a>Transcriber's Note</p> +<br /> +Some inconsistent hyphenation and spelling in +the original document has been preserved.<br /> +<br /> +Typographical errors corrected in the text:<br /> +<br /> +Page 62 Ge11e changed to Gellé<br /> +Page 67 Bruneleschi changed to Brunelleschi<br /> +Page 142 Röol changed to Röll<br /> +Page 175 charboneux changed to charbonneux<br /> +Page 253 eat changed to ate<br /> +Page 354 lairs changed to fairs<br /> +Page 377 Boulay changed to Bouley<br /> +</div> + + + + + + + + +<pre> + + + + + +End of the Project Gutenberg EBook of On the cattle plague: or, Contagious +typhus in horned cattle. 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You may copy it, give it away or +re-use it under the terms of the Project Gutenberg License included +with this eBook or online at www.gutenberg.org + + +Title: On the cattle plague: or, Contagious typhus in horned cattle. Its history, origin, description, and treatment + +Author: Honore Bourguignon + +Release Date: June 22, 2011 [EBook #36496] + +Language: English + +Character set encoding: ASCII + +*** START OF THIS PROJECT GUTENBERG EBOOK ON THE CATTLE PLAGUE *** + + + + +Produced by Barbara Kosker, Bryan Ness and the Online +Distributed Proofreading Team at https://www.pgdp.net + + + + + + + +-----------------------------------------------+ + | Transcriber's Note: | + | | + | Inconsistent hyphenation and spelling in the | + | original document have been preserved. | + | | + | Greek words are transliterated and marked | + | +like so+. | + | | + +-----------------------------------------------+ + + + + + ON THE + CATTLE PLAGUE: + OR, + Contagious Typhus in Horned Cattle. + + ITS HISTORY, ORIGIN, DESCRIPTION, AND TREATMENT. + + + + + BY + H. BOURGUIGNON, + + Doctor of the Faculte de Paris, Fellow of the Societe de Medecine + de Paris; Laureate of the Institute of France, Member of the + Legion of Honour, etc. + + + + + "Scribo nec ficta, nee picta, sed quae ratio, + sensus et experientia docent." + + + + + PHILADELPHIA: + J. B. LIPPINCOTT & CO. + LONDON: J CHURCHILL & SONS. + 1869. + + + + + TO + MISS BURDETT COUTTS. + + + MADAM, + +The numerous services which you have rendered, and the interest you have +shown in the calamitous epizootic which at this moment decimates the +noble herds of England, have prompted me to dedicate the following pages +to you, satisfied that I am only giving public expression to the homage +felt for you by many of your fellow-countrymen. + +I have the honour to be, Madam, + + With respect, your obedient servant, + + H. BOURGUIGNON. + + + + +PREFACE. + + +Nations, during the successive phases of their evolution on the globe, +in which they advance from a state of infancy and barbarism to one of +virility and civilization, from civilization to decadence or senility; +and from decadence to their final extinction, are liable to numberless +calamities. + +These calamities are produced by moral causes, and are then called +social Revolutions; and in other instances from physical causes, and +then they are termed Cataclysms, Epidemics, or Epizootics. + +In these crises, the initiative and devotion of individuals, the public +administration, and the application of knowledge acquired in the Arts +and Sciences, afford collectively an infallible criterion for +ascertaining the position which a nation occupies in the scale of +civilization, and the value of its religious, social, and political +institutions. + +Calamities always leave behind them disasters and victims, but they +bequeath also a precious legacy. Nations which are called upon for fresh +and progressive efforts, find in the experience they have gained a new +source of strength and means of future greatness. I am convinced that +this will be the case with England; though, helpless for the moment, and +unable to stay the Cattle Plague which now ravages her entire extent, +she will in future be found better prepared to resist the inroads of +such a direful enemy. + +No branch of human knowledge has been more rudely tested during the +present epizootic than medical science. Many persons have been astounded +at its helplessness; but if they had reflected at what a distance +medicine has to follow in the wake of the exact sciences by which it is +furnished with instruments for prosecuting its researches,--that +organic chemistry progresses but slowly,--that the Cattle Plague was +entirely unknown to the present generation of medical men in +England,--and that the means for its scientific and practical study have +been therefore wholly wanting, they would have been less surprised to +find that it is as difficult to cure the Cattle Plague as it, is to cure +phthisis, cancer, hydrophobia, and the cholera, against which medicine +but too often is of little avail. + +In times of great national calamity it behoves every one to contribute +in proportion to his talents, fortune, or abilities, to alleviate the +effects of the common misfortune. The poor man's mite, and the honest +intention of the most insignificant, when added to the budget of common +efforts, have their relative value; and it is for these reasons that I +have published the following monograph on the Cattle Plague. + +If it assists in any way to the extinction of the present epizootic, or +if it serve to point out the necessity of combining the study of +comparative pathology with that of medicine, I shall feel that I have +contributed something which may favour my claim to be enrolled among the +citizens of England. + +This book, as may easily be seen, was originally written in my native +language. A few kind and obliging friends--more particularly Mr. Taylor +Sinnett, Drs. Clapton and Gervis, of St. Thomas's Hospital, and Mr. +Berridge, of the British Museum--have rendered me the greatest +assistance in the translation. Without the guidance of such competent +auxiliaries I could not have performed my arduous task. + +I therefore beg to return to those gentlemen, and to all those who have +assisted me on this occasion, my sincerest and most grateful thanks. + + H. B. + + + + +CONTENTS. + + + PAGE + + Introduction 1 + + + FIRST PART. + + The History of the Contagious Typhus of the Ox, from + the remotest Times down to the Present Day 5 + + + SECOND PART. + + CHAPTER I.--On Typhus Disease in general, and the + Typhus which affects the Ox in particular 72 + + CHAPTER II.--The Origin and Causes of the Ox-Typhus 84 + + CHAPTER III.--Description of the Contagious Typhus + of the Ox; its Symptoms, Course, Progress, &c. 140 + 1. Symptomatic Characteristics 141 + 2. Lesions found in the Bodies after Death 163 + 3. Diagnosis--Prognosis--Use of the Flesh of + Animals--Danger of direct Absorption 173 + 4. General Considerations on the Typhus, and + Recapitulation of the Symptoms 191 + + CHAPTER IV.--Treatment of the Ox-Typhus 206 + 1 & 2. Means and Measures to be employed + to resist the Causes of Contagious Typhus + of the Bovine Species 208 + 3. Curative Medication 237 + 4. Hygienic Measures to be taken against the + Extension of the Contagion--Acts and + Orders concerning sanitary Police Regulations 257 + + + THIRD PART. + + To Farmers and Graziers 281 + + + FOURTH PART. + + Suggestions on the Improvements to be effected in + the Study of Medical Science, in order that we + may be in a Condition to confront Disease generally, + and Epizootic and Epidemic Diseases in particular 311 + + + APPENDIX. + + Various Documents 337 + + + + +INTRODUCTION. + + +Everyone is talking of the CATTLE PLAGUE! But why should we +borrow this sinister and gloomy denomination from the middle ages and +from the people's vocabulary? Is this, then, an unknown and incurable +disease? Is this the first time that it has made its appearance on the +soil of Great Britain? To judge by the manner in which the diffusion of +this complaint has been met, accounted for, explained, and discussed, +one might imagine it was so; and yet the mere observation of its causes, +its symptoms, and its signs and effects on the bodies of the diseased +animals, besides a few references to the medical library, would easily +have testified that nature did not wait until the second half of the +19th century to generate a new distemper. No! Nothing new has appeared +for a long time in the worlds of space. The cosmic phenomena pursue +their perpetual course, and the organic phenomena, _a fortiori_, do the +same. Life, throughout the whole range of the animal kingdom, whatever +may be its changes and fluctuations, submits to the fixed and invariable +laws which hold dominion over health and disease. Our presumption and +ignorance alone can account for the astonishment we manifest, not only +when we witness great general calamities, but even when we look upon +those simple morbid derangements which organic matter, both animal and +vegetable, is continually undergoing on the globe, in the natural +progress of destruction and dissolution. + +The habit we most of us have contracted of confining our observations to +the phenomena which strike our eyes, instead of fixing them on the +general causes by which these phenomena have been produced; the +forgetfulness of some, in others the want of acquaintance with general +and comparative pathology, have in this instance led many conscientious +inquirers to misapprehend both the nature and the treatment of the +cattle complaint. It is in vain that we have subdivided and classed +medical science--in vain that we have arbitrarily instituted a +veterinary medicine and a human medicine; nature, in her acts, has no +such subtleties. With nature, organic matter is organic matter, life is +life; and although it may be true that both organic matter and life +become more complex, and continue to rise in perfection till they reach +man, it is quite as true that the laws of pathology and physiology are +the same in all, and that it is just as difficult to cure the typhus of +the ox as that of man. As, therefore, it is because we overlooked these +fundamental truths, that the outbreak of the cattle distemper found us +unprepared, we must treat the subject with all the gravity which is its +due. + +Let it not, however, be feared that the special fact of the _so-called_ +Cattle Plague will be lost sight of amidst a crowd of scientific +generalities. No; collateral reflections, seemingly foreign to the main +argument, will concur to elucidate it; and all these rays of light will +converge to a common centre, reflecting, we flatter ourselves, some +evident facts and practical truths. + +This work on the contagious typhus of the ox is divided into four +principal parts. + +The first part contains the history of this typhus from the remotest +times down to the present day. It is divided into several sections. + +The second part, which gives the description of the disease, is +subdivided into four chapters. + +The first chapter treats of general typhus, in order that a perfect +understanding may be arrived at as to the name and definition of the +particular distemper which affects the ox. + +The second relates to the causes and origin of the disease. + +The third treats of its symptoms, its progress, &c. + +The fourth contains its mode of treatment. + +The third part gives some plain instructions for the benefit of farmers, +cattle-dealers, and dairymen. + +The fourth part gives a development of the scientific means and +safeguards to be adopted, in order that this country shall never relapse +into that state of helpless panic to which a want of preparation exposed +it when the present epizootia began its ravages. + + + + +FIRST PART. + + _The History of the Contagious Typhus of the Ox, from the + remotest times down to the present day._ + + +I. + +General, local, and particular causes of destruction are constantly +reacting on organized creatures, and these causes account for those +_epiphytic_ diseases which infest plants, the _epizootic_ diseases which +spread mortality among the brute creation, and the _epidemic_, which +strike and are fatal to the human species. Thus it is that we +particularize at present, in the vegetable kingdom, the disease which +has attacked the vines, olive-trees, and potatoes; in the animal +kingdom, the silkworm sickness, and the cholera, and the typhoid fever +of cattle: so that we may safely say, that one or other of these +diseases is always, at a given moment, raging in some part of the globe +among some species of animal, either birds, pigs, horses, sheep, horned +cattle, or, in fine, attacks man himself. + +When, however, the peccant invasion falls only on the vegetables and +animals situated at our antipodes, we seldom hear of the ravages it +commits; and when we do, forgetful of the affinity which links together +all the organic beings on the earth and their mutual dependence, nothing +can exceed the indifference we show to these calamities. Then, when the +danger threatens us nearer home, or when the evil has invaded us, we +have recourse to quarantine as the grand preservative to shield us. But +this preservative remedy is most frequently deceptive--a mere illusion; +for the real plague, typhus and cholera, borne along by the winds of +heaven, pass over the longest distances and the highest obstacles, and +baffle all our calculations; teaching us, by their successive returns, +that we shall continually be exposed to their destructive havoc so long +as we neglect to eradicate the evil at its original source, that is, in +those countries from which it emanates. + +And this is the place to observe, that the cholera morbus threatens to +keep a permanent footing in the English possessions of India, because +the public works, by means of which the great rivers used to be confined +to their beds, have not of late been repaired and kept in good order in +those countries; owing to which neglect, their waters overflow the +plains, leaving, when they subside, those pestilential deposits which +afford a perpetual incubation to the cholera. + +We are induced to dwell thus on the general causes of these diseases, +because the sick plants, on which dumb animals feed, and the sick +animals, on which man himself feeds, have a continual relation of cause +and effect; and we shall have to refer to this subject and give it +weight, when we come to speak of the treatment of these diseases. + +It is an important fact, which deserves our most pointed attention and +consideration, that the vital resistance inherent in the animal frame to +withstand the attacks of these contagious diseases, is very far from +being the same throughout the whole kind. Man, in this respect, is the +most favoured and best fortified; he is able, without much +degenerating, to inhabit any latitude, to go with a sort of impunity, if +his calling require him to do so, amidst the most pestilential +emanations, and to continue for hours inhaling their baneful fumes. We +could quote many striking examples of this resisting power in man. But +there is one which we have recently witnessed, and which all can +appreciate. We refer to the slaughter-house of the great Metropolitan +Market. Here we saw, in lumps and fragments, every variety of corrupt +_detritus_ of animals which had been seized with the contagious typhus; +we saw the animals, too, being felled and slaughtered and dissected, in +a high temperature which rendered the air so poisonous that we could +hardly breathe it; yet amidst all this infection the workmen employed to +move and handle these revolting wrecks appeared indifferent to the +scene, and quite in their usual health. No living animal besides man +could stand such a trial; no other could breathe for hours, and day +after day, like these workmen, an atmosphere so charged with decomposing +impurities. + +We say, therefore, that man may expose himself, with less danger to his +life than any other animal, to those pernicious causes which produce and +develop contagious diseases. Next to him, with respect to this power of +vital resistance, come the omnivorous animals, then the carnivorous, and +last of all, the herbivorous, in which this faculty is very feeble +indeed. + +This prime consideration, to be fully understood and appreciated by +unscientific readers, would require explanations beyond the scope of +this work. Let us, however, for the present establish the fact, that +herbivorous animals, such as sheep and horned cattle, offer but a very +weak resistance to the causes which generate infectious and epizootic +diseases, and let us do our best to prove it by demonstration; for if +this truth be once admitted, we shall therefrom deduce that it is the +duty of man constantly to surround these frail and delicate creatures +with special care and attention, if he wishes to prevent their being +decimated from time to time, and if he would likewise avoid the +consequent injuries to himself--the loss of health and money accruing +from this deterioration. + +So long as the herbivorous or grass-eating animal is properly fed; so +long as he browses on fat pastures; so long as his blood retains those +physiological elements which are the prime condition of health, he can, +and does, resist the causes of most contagious maladies. But if a hot +summer and a long continuance of dry weather chance to curtail, in +temperate zones, the usual abundance of his fodder, then comes the fatal +change: the blood is impoverished, the secretions are debilitated, a +strange languor runs through the system, the vital resistance is +unnerved, and he becomes an easy prey to those noxious influences which +were encountered before without injury whilst his provision was +abundant. + +This is a fundamental matter. We therefore beg leave to support and +justify our argument by borrowing some additional evidence from prior +labours of ours, accomplished at the Ecole d'Alfort, near Paris, +conjointly with Professor Delafond, whose name has so often been cited +in the public journals in connexion with the cattle plague. + +All vegetables and animals; with the exception of _adult_ men, whenever +their health declines from any cause (but more particularly from +paucity of food), spontaneously generate microscopic parasites, or very +minute insects, the germs of which are inherent in their system. A flock +of fleecy animals, wasted by deficient food in dry and parched meadows, +becomes attacked in due time by a parasitical cutaneous disease, known +as the _itch_, which is enough, if not checked, to destroy the whole. +Now, all that is required is to remove this flock to a more fertile +soil, where there is plenty to feed them, and the disease will disappear +of itself without any treatment. Deficiency of food destroys the health +of animals, and abundance of food overcomes disease in them. + +A sheep affected by this parasitical disease may, without any fear, be +placed in a flock of healthy sheep, for he will not propagate the +distemper; but if instead of being sound and healthy, the flock is in a +weak declining state, this contaminated animal will diffuse the disease +with frightful rapidity, and may cause their entire destruction. These +facts may seem startling, but we are only speaking after the +incontestable authority of experiments. + +We selected six healthy sheep, which we kept well supplied with +provisions; we covered these healthy sheep with parasites (acari). On +every one of these sound, well-fed sheep, the microscopic animalculae +died off without generating the cutaneous disease; for the blood, the +humours, and the skin of sound and healthy sheep constitute a soil +unfavourable to the propagation of these parasites, and actually starve +them to death. + +After this first experiment, we subjected these six sheep to a deficient +diet; they grew lean, their blood was impoverished, and then all we had +to do was to lay upon them not thousands and thousands of these +parasites--as we had done in the first instance--but one solitary female +in a state of fecundity; and the parasitical distemper unfolded itself +so fiercely as to cause the death of three of these sheep on which the +test was allowed to run its course; whilst the other three sheep, having +been restored in time to a recoverable condition just as they were about +to drop off, were thoroughly cured, without any special treatment, by +the sole influence of good food and ordinary hygienic attention. + +Other tests, similar to these experiments, were applied to dogs, horses, +and horned cattle. A lean and scraggy dog, covered with parasites and +eruptions, with eyes running foul humour, a dog which could neither run +nor stand, and which was reduced to the last stage of wasting marasmus, +was rescued from the jaws of death and thoroughly cured without special +treatment, by the sole influence of a rich restorative diet. This dog +afterwards became a fine hunting hound, beautiful in shape, and +admirable for his sportive attributes. + +These experiments having been submitted to the judgment of the Academie +des Sciences in Paris, were honoured with its approval, and the reports +concerning them were printed at the Academy's expense, and crowned at +the competitive examination. + +The vital resistance of horned cattle is so feeble, that those animals +which are periodically exhibited in the north of London, though +certainly chosen from among the most healthy and robust, could not herd +together in large numbers for the space of a month in the Agricultural +Hall at Islington, without sinking under infectious and contagious +diseases--almost one and all. Under the conditions in which we see them +in that Show, a single month would be sufficient to produce almost their +complete destruction; for even a single week, which is the usual +duration of their confinement, affects them so much as to render a large +proportion of them unhealthy. + +Every one knows how apt cavalry horses are to sicken and die off during +a campaign. Every one has heard of the fearful ravages amongst the +horses of the Allied armies during the Crimean war, when many companies +were dismounted owing to this mortality. + +Let us now transport ourselves in thought into the middle of those +immense steppes where vast and innumerable herds of herbivorous animals +are being bred for our supply, and consider what will be the effects on +their health and life if they should be afflicted with a scarcity of +forage, in consequence of this long dry summer. + +It is unnecessary to say that there exist in Russia, in Hungary, in +Australia, in North and South America, and in many other parts of the +globe, large tracts of country which are still uninhabited, whose +uncultivated soil supplies with food great numbers of sheep and cattle. +These spacious tracts, known as moorlands or steppes, particularly +abound in Russia, on the banks of the Wolga, the Don, the Dnieper; in +Hungary, on the banks of the Danube; and also in South America, in the +republics of Venezuela, New Granada, Columbia, &c. + +Now, in hot and rainy seasons these steppes teem with rich and luxuriant +verdure; the plants growing up in the marshes are prolific and abundant, +and even those parts of the wild moors which produce nothing but heath +are capable of feeding and fattening flocks and herds. + +Under conditions so auspicious as these, animals may still suffer, but +in what way? By excess of food, or repletion. They are in general robust +and healthy, and thus fortified they inhale without detriment the +deleterious gases of oxygen with carbon, carburetted hydrogen and the +like, exhaled by the plants which grow out of the swampy soils. Thus +protected, too, they are proof against the fluctuations of the seasons, +and against every injury which threatens them; and their strong and +sound condition enables them to sustain the fatigues of their long and +arduous journeys, and to supply the rich countries of the West with +their flesh, fleece, and hides. + +When the seasons have thus conveyed a due proportion of heat, water, and +electricity to the elements of the soil, both plants and animals conduce +to the comfort and health of man, and fulfil his expectations. But the +laws of nature are involved in mystery. Good and evil go hand in +hand--death and life travel close together--and a few years of +prosperous harvests are almost invariably followed by blight, +barrenness, and scarcity. Most men think only of the present time, and +this imprudence and want of foresight prevent farmers and great cattle +proprietors from collecting and holding in reserve the requisite stores +of sustenance to supply their sheep and oxen during these barren +seasons. Sickness then breaks out, and these helpless creatures perish +in vast numbers, to the detriment of their owners' best interests. + +And truly, when continual rains cause the rivers to overflow, when the +plains are drenched and soaked, or when a burning sun scorches the +ground, herbivorous animals wander in vain from field to field in quest +of sustenance to restore their strength, or of pure and healthy water to +slake their thirst; their vital resistance dwindles away, deleterious +gases poison and bewilder them, their blood is debased, and as Ovid +says, + + "Corpora foeda jacent, vitiantur odoribus herbae." + +And since these mild and harmless animals, which seem to have been +created merely to clothe us, and to nourish us with their milk and +flesh, have not been endowed by nature either with the intelligence, or +the activity, or the cunning, or the invention, or the skill bestowed on +the omnivorous and carnivorous species, hard is their fate under the +pressing needs of hunger. Peaceful creatures, they browse in vain on +deleterious plants on a sterile soil; their external and internal +teguments now afford a favourable seat for the propagation of +parasites--for the _parasitogenia_; and soon after a general _adynamia_, +or relaxation of the fibres, delivers them up without resistance to the +morbific elements of the infectious diseases to which they are exposed, +where the languishing, the sick, and the rotting are herded together, +and they are carried off by hecatombs by this wasteful and devouring +typhus. + + +II. + +We may readily conclude, from these general observations on infectious +and contagious diseases, that they must have existed in all former ages; +and if in our present advanced state of civilization they are so +destructive, we may be sure that in those remote periods they must have +been, both as regards man as well as the brute creation, the cause of +general extermination, in whatever parts of the earth they prevailed. +And indeed, whenever we refer to ancient or modern history, we are +continually struck with the analogy which exists between the epidemic +diseases signalized by the general name of PLAGUE, and which +decimated all the living beings, and those which more recently, and at +the present moment, have startled the world by their fatal effects on +men and animals. + +Moreover, we cannot too often repeat the fact--in order that those +documents relating to the past which contain useful instruction may be +examined and searched into--that the physiological and pathological laws +which rule and determine the phenomena of organic matter, whether in +health or sickness, were, like the laws of chemistry, electricity, and +astronomy, originally established at the time of creation, and that +matter submits with passive obedience to the laws of transformation and +transubstantiation, which are the absolute condition of life. These are +the eternal laws of which a synthesis so admirable is furnished by the +Gospel, in this short injunction, "_Take, eat, this is my body; drink, +this is my blood._" + +Now, if man, who is the sovereign master of this matter, did not take +care to regulate and modify it for his own benefit and the benefit of +all living creatures on whom his own life depends, as well as his wealth +and happiness; if he did not seek thereby continually to diminish the +sum of evil, and to extend the sum of good which it is his mission to +increase, he would violate these laws, which are inherent in matter, and +which have existed for his use since the creation of the world. + +We must likewise believe that those PLAGUES which are spoken of +in the Bible, those which Homer alludes to, that which is related by +Plutarch, and which succeeded the general drought in 753 before Christ; +those mentioned by Titus Livius, Virgil, Ovid, and other Latin authors, +the most virulent of which plagues raged in the years 310, 212, and 178 +of the Foundation of Rome, resembled the epidemics or plagues which are +witnessed in our own day. + +The plague of 212 swept away all the inhabitants of Sicily, cattle as +well as men; that of 178 destroyed all the priests, who sought in vain +for victims free from the contagion, to offer them up as sacrifices to +the offended Gods. + +Cecilius Severus gives a most striking description of a pestilential +disease which, in 376 A.D., swept away all the cattle in +Europe. Judging from his account of that scourge, we may fairly believe +that the distemper he has described was identically the same as the one +which has just broken out in England. "A universal distaste, sudden +dejection, vertigoes, spasmodic tension in the limbs, _a painful_ +_swelling of the lower belly_, violent affections of the nerves, sudden +death--everything shows the presence of a pestilential ferment, which +irritates the solids, infects and vitiates the fluids, which is the +cause of the putrefaction of the humours, manifested by the swelling of +the lower belly, which in that case depends on a putrid fermentation so +as to disengage air." + +A piece of iron, representing the sign of the Cross, was heated in the +fire, and when red-hot was applied to the forehead of the sick animals; +and this remedy was looked upon at that time as the most effectual they +could apply. + +Gregoire de Tours makes mention of an epidemic, the result of a long dry +summer, which, in 592, was very fatal in its havoc, sparing no living +creature whatever. + +Andre Duchesne, in his "History of England," speaks of an epidemic +which, in 1316, during the reign of Edward II., owed its origin, on the +contrary, to a long season of rains. + +The celebrated physicians Ramazzini and Lancisi relate that in 1711, an +ox which had been imported from Hungary, that constant focus of typhus, +displayed the most deadly form of the cattle disease, in the Venetian +territory, although no alteration in the air or waters had been observed +in Italy, and the seasons had been regular and the pastures abundant. +The contagion spread into Piedmont, where it carried of 70,000 head of +cattle; thence it extended to France and Holland, each of which +countries lost 200,000 of these animals. The trade in hides introduced +the distemper into England, where it proved no less fatal. It was the +same in the other countries of Europe. + +In this disease, the intestines of the affected cattle were, as in the +present epizootia, inflamed, and strewed over with livid spots and +ulcerations, and the blood, though apparently fluid in the body of the +animal, _coagulated directly after it had issued from the vein_. + +Herment thence concludes, that this epizootia is nothing more than an +inflammation of the blood. Lancisi advised his contemporaries to put to +death without pity every animal which was affected or seemed to be +affected with the disease; and it was in England that this spirited +resolve was first acted upon. + +The three counties of Middlesex, Essex, and Surrey arrested the course +of this contagion in less than three months, by adopting this measure; +whilst in the rest of the stricken counties of Great Britain, and +likewise in Holland, where this decisive course was not taken at all, +the disease prevailed among the cattle for several years. Since that +time, it has been insisted on by some authors, that the barbarous +process of general extermination offers the most effectual remedy which, +in our present state of ignorance and improvidence, we could have +recourse to, in order to check the diffusion and the duration of this +fell disease. + +The learned Goelicke describes an epizootia which was witnessed in 1730, +at Frankfort-on-the-Oder. His narrative, written with a masterly hand, +might very properly be applied to the disease which we are now +considering; and the treatment recommended by this earnest and vigilant +observer is so wisely deduced from the symptoms, that even in the +present day we might take that treatment as a model. + +We could have borrowed much more largely from this source of +biographical researches had we not deemed that these quotations would be +sufficient for the purpose we had in view in this work. But from these +authorities we think it may justly be concluded, that infectious and +contagious diseases among horned cattle have frequently appeared from +the remotest times down to the middle of the eighteenth century. + +All these attacks of epizootia were a frequent and severe cause of +suffering and misery among animals and men; but the ravages which they +left behind them were of slight importance each time, if we compare them +with those attending the epizootia which towards the year 1746 affected +the animal kingdom. This dreadful scourge lasted ten years, and swept +away nearly the whole race of horned cattle throughout Europe. It was +closely studied and thoroughly understood in its causes, its symptoms, +and its treatment by the scientific authors of that day, and those +writers, more judicious than we, did not designate the malady by the +title of PLAGUE. This particular visitation deserves to fix our +attention in an especial manner, not only on account of its striking +resemblance to the disease which now makes us all so anxious, but +because it induced two English physicians, Malcolm Flemming and Peter +Layard, to write on this disease two accounts or statements which are +equal, if not superior, to all the volumes which have since appeared on +the subject of the Cattle Disease. There is no help for it, and our +pride must bend itself to the acknowledgment: these two men, our seniors +by a century, were men of quite another stamp. Their expositions, +enriched with quotations from the Greek and Latin authors, abounding in +facts, ingenious insights and inferences, are far superior in merit to +the multitude of voluminous works which have been written and published +since then. It would be easy to prove that these two sagacious inquirers +far better understood than we have done the real nature of this cattle +disease, and that we must be grateful to them for first opening the way +which all of us must take in order to discover the preventive and +curative means of which we are still ignorant. + +Let us observe, in passing, that these two physicians, who appear to +have been scarcely known, enlightened by the effects of the inoculation +of small-pox, then practised from man to man, appear to have first +conceived the idea, now practised in Russia, of preventing the +propagation of the contagious cattle disease by means of inoculation; +and we may raise the interest of this remark by reminding the reader +that their experiments to inoculate cattle were made in 1757, eight +years after the very year which gave birth to the future inoculation of +man with animal virus by the celebrated Jenner. By this it would appear +that the twofold honour of applying the method of inoculation as both +preventive and curative means in respect of contagion in cattle, and as +the preventive means by the variola of the cow to resist the ravages of +the small-pox in man, is the indisputable claim of English +physicians.[A] + + +III. + +Very little is known of the origin or first outbreak of the epizootia +which produced such fearful ravages in the middle of the eighteenth +century. Some suppose that it first appeared in Tartary, where it +occasioned a disorder twice as extensive in its pernicious effects as +any similar distemper which had been known up to that time. Thence it +passed into Russia, from which it spread on one side into Poland, +Livonia, Prussia, Pomerania, and Holland, and from that country into +England; on the other side towards the East, it invaded the Turkish +Empire, Bohemia, Hungary, Dalmatia, Austria, Moravia, Styria, the Gulf +of Venice, Italy, Spain, Portugal, France, the banks of the Rhine, and +Denmark. + +But another opinion has assigned Bohemia as the source from which this +destructive epizootia took its rise, and its supporters allege that +during the siege of Prague the cattle feeding in its plains had been +deprived of their usual fodder by the continual _razzias_ of the French +to supply their own cavalry. + +Be this as it may, this virulent cattle disease having at length +assumed the proportions of a public calamity, the several governments +were obliged to take it into serious consideration, and the medical +faculties and most celebrated physicians began to make it the subject of +their studies and reports. In France, therefore, the professors of the +faculty of Paris and Montpellier, suspending every other pursuit, +devoted their most assiduous care and attention to dumb animals. + +Sauvages, the Dean of the Faculty at Montpellier, drew up a most +philosophical and learned account of the prevailing disease, in which, +like Stahl, he forgot probably for a moment the part which, in the +progress of distempers, he ascribes to the soul. + +The professors of Paris, very famous in their day, but who, having left +behind them no works so valuable as the "Nosologia" of Sauvages, are now +completely forgotten, likewise addressed the result of their inquiries +and lucubrations to the King. + +Doctor Leclerc was sent into Holland, whence he brought back a Memorial, +which was a reflex of the opinions he found current in Denmark, and +which has been transmitted to us in the _Memorials of the Royal Society +of Science at Copenhagen_. + +It is evident from the reflections found in the writings of Malcolm +Flemming, Layard, and other competent observers, that this formidable +epizootia was in its character identical with the one described by +Ramazzini and Lancisi in 1711; and we feel warranted in saying, after +having examined every work of any importance which has treated of that +visitation, that it resembles the disease now prevailing among cattle, +in its march, in its symptoms, and in its gravity. We believe that these +three visitations constitute but one and the same malady, occurring at +three different periods. This appears to us a most important fact, for +if such be the case, the tentative treatment of that time deserves our +most particular attention. Consequently, a few retrospective glances may +perhaps be permitted us, in considering the subject of cattle disease. + +The medical professors (including several English physicians), who +observed and described the epizootia of 1745, divided the same into +three periods. + +The duration of the disease, when it passed through all its phases up to +the death of the affected animal, consisting of from ten to twelve days, +they usually ascribed to each of these periods or stages an average +continuance of three or four days. + +_1st Period._--After a few days of latent incubation, which the observer +could not suspect, the sick animal betrayed signs of the morbid state +which was about to declare itself, by his careless feeding, by drooping +his head, and by exhibiting the deepest dejection of spirits in his +attitude and look. Rumination, already imperfect, soon ceased +altogether, the appetite failed, the horns, ears, and hoofs were cold, +the hair grew stiff, the tongue and mucus looked white; the eyes were +tearful and fixed, the hearing obtuse, whilst, in the cows, the supply +of milk diminished. In cases of unusual gravity, transient shiverings +testified to a serious disturbance in all the animal functions. These +shiverings were followed by a violent fever, the blood became inflamed, +the breath hot, the respiration hurried and sometimes attended with +slight coughing; when, if too violent a repercussion was transmitted to +the nervous centres, the pressure on the vertebral line became +intolerable, and the animal, seized with vertigo, and almost delirious +with pain, would fall during this first period, as if struck by +lightning. + +The same phenomena are sometimes observed in the typhoid fever of man, +which offers moreover some analogy with the contagious typhus of the ox; +but as the ox and the horse have likewise the real typhus fever, they +may some day supply us with the preventive virus for that fever, in the +same manner as the cow now supplies us with the preventive virus for the +small-pox. + +_2nd Period._--In most cases the disease pursued its course with greater +or less regularity; the sick animal experienced gnawing pains or +twitchings, and spasmodic shootings in the limbs, apparently attended +with pain. His thirst was insatiable, but he had no appetite, the +functions of the bladder and intestines were impeded, then diarrhoea +supervened, accompanied with dry, fetid, and sometimes bloody excreta. +Thick viscid mucosities dripped from the nostrils, mouth, and eyes. The +dorsal regions and the loins were constantly aching, headache and +sleeplessness were permanent. The animal continued either standing or +lying down, and if he wanted to rest, he could not bend himself +gradually, but would fall like an inert mass to the ground. + +_3rd Period._--Diarrhoea was continual, becoming more fetid every day, +the wasting of flesh made rapid strides; the cellular tissue beneath the +hide was filled with gas along the vertebral channels and under the +abdomen; the nostrils were stopped up with mucosities, the animal could +only breathe through the mouth, puffing and blowing aloud as he drew in +the air; and at last pustular eruptions showed themselves on various +parts; but as this depurating crisis was insufficient, the poor beast, +in this final period of the attack, fell a sacrifice to it between the +seventh and twelfth day. If he chanced to be lying down his agony was +slow, but if standing, he would sink upon himself, and expire at once. + +In this dreadful epizootia, very few of the smitten cattle survived--not +more than four or five in a hundred; and in these favourable cases, the +symptoms presented certain signs and critical phenomena of a happy omen. +In these rare exceptions, the pulse did not exceed seventy, the +beatings of the heart were always perceptible, the patient did not +refuse to drink, the continuous fever exhibited no aggravation at night, +pustular eruptions and tumours appeared on the dewlap and the fore +limbs, and the epidermis over the mouth and nostrils peeled off about +the twelfth day. + +When dissected, the bodies offered to view the following alterations, +the same having already been observed by Frascator during the prevalence +of the epizootia in 1514, and by Lancisi and Ramazzini during that which +was so fatal in 1711. The mucous glands of the mouth were livid, and +occasionally excoriated; the bronchial tubes were obstructed with +mucosities; the lungs, besides being partially congested, were sometimes +emphysematous, that is, inflated with compressed air. Of the four +stomachs, the rumen was full of food, the reticulum, the omasum, and the +abomasum exhibited purple or livid spots, according to their place. The +thin intestine and the thick intestine showed either a general +injection, scattered livid spots, or ulcerations, according as the fever +had worn the exanthematous or typhoid form; for the mucous membrane of +the digestive channels, and especially that of the intestines, displays, +like the external tegument in man and the brute creation, divers forms +of inflammation, analogous with the measles, the scarlatina, and the +small-pox; so that, if the typhoid fever in man, which is nothing else +than the small-pox of the intestines, is so frequently cured, it is +because the general morbid condition, the fever, often conceals +different intestinal lesions, albeit they seem to be similar in the +general symptoms, which taken collectively constitute the disease. + +The flesh of these diseased animals was blackish, and devoid of blood; +the animals which fed upon it, if uncooked, sickened afterwards, or +died. The wrecks of the bodies, and more particularly the skin, +sometimes retained a strength of contagion so deadly, that the mere +exportation of them was enough to cause its propagation, and to this +cause was at that time attributed the outbreak of the contagion in +England. + +An extraordinary case of this pernicious influence, which is related by +Hartmann, who observed this epizootia at its decline in 1756, will give +an idea of the subtlety of this malignant virus. + +A farmer who had lost an ox in consequence of that virulent distemper, +buried it in one of his fields. The following night a bear smelt the ox, +raked it up with his feet, ate a portion of the flesh, and a few days +after, the beast of prey was found dead in a neighbouring wood by a +peasant in the parish of Eumaki. The skin belonging to this bear was +magnificent. The peasant flayed the animal and carried home his skin in +triumph. But his triumph was short; for that same night the poor +countryman fell ill, and died two days after the attack. The magistrates +of Wiburg, having heard of this occurrence, sent orders to have the +infected skin burned. Meanwhile, the skin had been given to the curate +of the place as a compensation for the offices of burial; but his +cupidity having persuaded him that this fine skin could not have +destroyed the peasant whom he had just buried, he did not burn it at +all, but induced another peasant to clean and dress it for him. This +simple fellow and two other clodpoles, who assisted him in the +preparation, fell ill, and all three of them died in the course of a +few days. A new and peremptory order now came from Wiburg to burn this +skin, to burn the house in which it had been dressed, to burn even the +presbytery itself, should it be deemed necessary. The skin had already +passed through several hands. However, the curate being still reluctant +to part with it, took it home again. "Can it be possible," said he to +himself, "that this skin has really proved fatal to life? What can have +been the cause, I wonder?" At the same time he rubbed it in his hands +and smelt it. Unlucky curate! A few days afterwards he himself was taken +ill and died. (_Memoirs of the Academy of Stockholm._) + +A native of Clermont Ferrand, in the department of Puy de Dome, in +France, the birth-place of Pascal, one day finding an ox which had died +of the epizootia, stripped off the skin and carried it away. After his +return home, the black typhus, and then gangrene, broke out on one of +his arms, which had to be cut off, and the patient died of the effects +of the amputation. + +A butcher having slaughtered an ox smitten with this typhus, sold the +flesh for meat to some soldiers of the Regiment Royal Baviere, then +garrisoned in one of the towns of Languedoc. All those who partook of +this meat were seized with diarrhoea, dysentery, and fever, and +several of the sick soldiers very nearly died. The butcher, whose +avarice had caused all this mischief, had richly deserved some exemplary +punishment, and some of the sufferers proposed that he should be hanged +outright, but the majority, more clement, sentenced him to be beaten +black and blue with horsewhips. + +The popular saying, _when the beast is dead the poison is dead_, being +generally true, the virulence of the contagion, in the above instances, +possessed venomous properties of an exceptional character, for if every +sick animal slaughtered by the butchers and sold to the consumers, or +those which had been flayed for the sake of the skin, had contained so +murderous a virus in their tissues, the number of victims to the +contagion among the human species would have been appalling. And in that +case, too, similar sacrifices would be witnessed at present, for it +cannot be doubted that, in the actual state of the meat market in +London, the people are now in the daily habit of eating the flesh of +cattle which are diseased. + + +IV. + +Physicians of different countries have naturally bestowed much time and +care in considering and discussing the nature of this epizootia, because +they have felt that a satisfactory theory and appreciation of its +principal phenomena, might afford the medical faculty a rational basis +for some special treatment. + +Layard and the physicians of Geneva have considered this cattle disease +to be _a malignant fever with an eruptive tendency_. + +In the estimation of the faculties of Paris and Montpellier, this cattle +disease, considered in its symptoms, was nothing more than _a malignant +fever essentially contagious_, the action of which appeared to tend +exclusively towards the skin, and therefore it was rational to provoke +external eruptions and deposits which, as they matured, diverted from +the centre the greatest part of the morbific matter. + +_The treatment_, to which, above all, we invite the reader's attention +(more particularly that of medical men), necessarily varied according to +the period of the disease. It was sometimes preservative, sometimes +curative, as the case might be. + +_The Preventive Treatment._--The farmers and cattle-breeders, whose +herds were still exempt from the contagion, mindful of the advice which +they received through the public press, took very particular care of +their cattle during this season of epizootia: they rubbed them over with +a brush, and washed them at least once a day; they sheltered them from +the inclemency of wind and rain; they took their milch cows, which until +then they had kept shut up in unhealthy cow-houses, into the open air of +the fields; they washed and fumigated the stables; they examined the +quality of the fodder and of the other articles of food; they added +marine salt to their drinking water, or poured salt water over their +forage; and above all, they took care that no foreign animal commingled +with their flocks and herds. + +Some physicians, on their side conscious of the duty which devolves upon +them in such seasons of calamity, instead of resting satisfied with +recommending remedies, betook themselves boldly to the work, and studied +the disease experimentally in respect to its propagation and prevention. + +Thus, for instance, certain Dutch physicians, in 1754, wishing to know +whether the morbid matter would transmit the disease by inoculation, +made incisions in the necks of some oxen, cows and calves, inserting in +the wound a little tow saturated with the morbid secretions discharged +from the eyes and nostrils. This direct inoculation having been +practised on seventeen animals, transmitted the disease to them all in +the course of a few days. + +The English physicians having been made acquainted with these +experiments, applied them to a more practical purpose, no longer to +discover whether the disease could thus be transmitted (for that had +been proved), but to find out (what was far more important) whether this +fearful distemper could be prevented and kept off. + +Malcolm Flemming, in 1755, merely suggested the idea of inoculation as a +preventive means, without proceeding to a course of experiments to +ratify his opinion. He intimates his notion in the following terms:-- + +"I apprehend that inoculation will stand the better chance of bringing +on the distemper, if the subject it is performed on is as young as +safety will permit, the vessels being then most absorbent, and the +animal economy most easily put into disorder. + +"But even in case the inoculation of calves should be found so +successful as universally to prevail, the method I recommend will not be +altogether useless; for, by being properly modelled and adapted to +circumstances, it may, I am persuaded, prevent contagion, and likewise +act as a preparative in any epidemical affection of the inflammatory +kind, not only in horned cattle, but likewise in all other quadrupeds +that civil society may think worthy of preservation, and even in the +human species." + +Layard, in 1757, devotes the seventh chapter of his work, "The Means to +prevent the Infection," to the consideration of the preventive +treatment, in which he says:-- + +"No one will think of bringing the infection into any place free from +it, merely for the sake of inoculating their cattle; but if the +contagious distemper be in the neighbourhood of a herd, or break out so +as to endanger the stock, the grazier or farmer may, by inoculating his +cattle, with proper precautions, at least secure his stock, since he can +house them before they fall sick, prepare them, and have due care taken, +knowing the course of the distemper. + +"Sir William St. Quintin, the Rev. Dr. Fountayne, Dean of York, and +other gentlemen have succeeded in inoculation: in Holland it has both +failed and succeeded. These gentlemen all inoculated with matter taken +from the running of the mouth, nose, or eyes. Professor Swenke mentions +that the beast from which he took the matter was recovering from the +distemper. A circumstance to be attended to is this:--had matter been +taken after the crisis, from a tumour, boil, pimple, or scab, either on +the back near the spine, or on the legs, the pus would have proved much +more elaborated, subtle, and infecting than that which, flowing with the +mucus of the nose, must necessarily be, in some degree, sheathed by this +glutinous excretion, though I am well aware how putrid and acrid it is +rendered by the disease. + +"That nothing may be omitted which in any shape can contribute to the +success of inoculation, due attention should be paid to the constitution +and state of the beast, no less in this practice on the cattle than on +the human species. Undoubtedly the young, healthy, and strong bid fairer +for a good issue than the old, sickly, and feeble; each of these +different constitutions demand a particular treatment, even in the +method of preparation; and however trifling it may seem to many--the +urging a necessity of preparation--I will venture to affirm that I have +seen excellent effects arising from a rational preparation, and fatal +events from want of preparation. I have likewise been witness of +unfavourable turns, merely from an injudicious preparation. + +"The beasts which are sanguine require moderate bleeding; those that +have but a small share of blood must have none drawn. The strong must, +besides moderate bleeding and purging, be kept on light diet, and their +body kept open. Thus, scalded bran, mixed with their hay and chaff, will +cool them. The weakly, and such as are inclined to scour, must be kept +on dry fodder, and have peas and beans given them to strengthen them. A +mess of malt, or a quart of warm ale, with a few spices, will be very +suitable for them. + +"Whatever diseases the cattle may be affected with, if time will permit, +they are first to be removed. + +"The cattle to be inoculated are first to be well washed, rubbed dry, +and then curried, to remove all the filth from the hair and skin. Then +they are to be placed in a spacious barn or stable, where the air is +temperate and no cold can come to them. There they are to be prepared +according to the direction already given, foddered with good sweet hay, +and watered with clear spring water; and if the distemper be not near, +they may be turned out into the air, near the barn or stable, and may +stay there a few hours in the middle of the day. + +"When it appears that the cattle are in perfect health, free from any +infection or disease, brisk and lively, neither costive nor scouring, +and chewing their cud, then the operation may be safely undertaken, and +henceforth they must be confined to the barn. + +"Since there is observed to follow the greatest flow of the contagious +and putrid particles separated from the blood, wherever the infectious +matter makes an impression at first, particular care must be taken not +to inoculate near such vital parts as the heart and lungs, nor near the +womb, if a cow with calf be inoculated; for, though rowels are properly +applied in the dewlaps to draw off the pestilential humour from the +breast, and in other cases beasts are frequently rowelled in the +flanks,--yet, in this operation, as matter is inserted by these channels +into the neighbouring vessels, those vital parts, or the womb, might +become the chief seat of the disease, and the event prove fatal. + +"To prevent such accidents, human beings have been inoculated on the +arms and legs, and now-a-days the arms are found sufficient. I would +recommend that the cattle should be inoculated about the middle of the +shoulders or buttocks, on both sides, to have the benefit of two drains. +The skin is to be cut lengthways two inches, deep enough for the blood +to start, but not to bleed much. In this incision is to be put a dossil +or pledget of tow, dipped in the matter of a boil full ripe, opened in +the back of a young calf recovering from the distemper. It may not be +amiss to stitch up the wound, to keep the tow in, and let it remain +forty-eight hours. Then the stitches are to be cut, the tow taken out, +and the wound dressed with yellow basilicum ointment, or one made with +turpentine and yolk of egg, spread on pledgets of tow. These dressings +are to be continued during the whole illness, and till after the +recovery of the beast, to promote the discharge; and then the wound may +be healed with the cerate of lapis calaminaris, or any other. + +"On the third day after inoculation, the discolouring of the wound, +whose lips appear grey and swollen, will be a sign that the inoculation +has succeeded; but the beasts, as Professor Swenke informs us, did not +fall ill till the sixth day, which answers exactly to the observations +daily made in the inoculating of children. Yet the Professor adds that +on the third day a costiveness came on, which was removed by giving each +calf three ounces of Epsom salts. + +"No sooner do the symptoms of heaviness and stupidity appear than the +beasts must have a light covering thrown over them, and at night +fastened loosely. They must be rubbed morning and evening, and curried, +till the boils begin to rise; warm hay-water and vinegar-whey must be +given plentifully. Should the beasts require more nourishment, dry meat, +such as cut hay, with a little bran, may be offered. I should be very +cautious in giving milk-pottage, even after the boils and pimples had +all come out, for fear of bringing on a scouring. However, this caution +is proper, that whenever milk-pottage be given, the vinegar-whey is to +be omitted for obvious reasons. In cases of accident, the same attention +is to be observed in the disease by inoculation as in the natural way, +and the medicines recommended are the same I would use; but by +inoculation there seldom is a call for any, so favourably does the +distemper proceed through its several stages. + +"The crisis being over, it will be proper to purge the cattle, to air +them by degrees, and to have the same regard in the management of them +as is laid down in the chapter on the method of cure." + +Such are the recommendations which Layard has prescribed for those who +have to practise inoculation as a preventive treatment; it would be +difficult to offer an example of greater prudence or precision. + +A certain number of oxen were, by means of this inoculation, protected +against the attack of the cattle disease; and this mode of treatment +was, as we shall afterwards explain, adopted in Russia. Unfortunately, +this rational and preventive treatment was discovered only at the end of +the epizootia, when already upwards of six millions of horned cattle had +fallen a sacrifice to the contagious fever. + +_Curative Means._--When the first course of the disease had left no +doubt of the attack, the sick animal was subjected to an appropriate +diet, and restricted to liquids either as medicinal decoctions, or as +alimentary beverages. The decoctions consisted of whey mixed with a +little vinegar, and nitred hay. The broths, or alimentary beverages, +consisted of a decoction of bread, and of water mixed with bran and +meal, whether of barley, oats, or wheat. + +At this stage of the curative process, the majority of physicians +recommended one or two bleedings, in order to abate the violence of the +fever, and of the congestions near the nervous centres and the lungs; +and as constipation prevailed at the time, they strove with the same +object to empty the digestive passages, the intestines, and the +stomachs, notwithstanding the difficulty that exists to produce this +result in ruminating animals. + +The purgatives employed consisted of a decoction of senna, mixed with +prune juice, with a little rhubarb or fresh linseed oil, infused in +their drink, or applied as a clyster in warm water slightly salted. +Those who practised polypharmacy administered at night a mixture of +nitre, camphor, red-lead, and rhubarb, in half a pailful of warm water; +and greatly did they boast of the active influence of this beverage. + +Some practitioners even endeavoured, in the first stage of the malady, +to accelerate its action on the skin by giving for that purpose warm +drinks, and by covering the cattle with woollen cloths, to promote +perspiration; but it was generally admitted that the sick animals +preferred cold drinks, and that they were particularly fond of +acidulated whey. + +In the second period of the distemper, the same drinks were continued, +adding thereto some theriac or Jesuit's bark, in order to lessen the +frequency of the diarrhoetic evacuations. They also provoked the +depurating secretions from the mouth, nose, and eyes, by repeated +washings; and as those animals, in which the running was most easy and +copious, seemed to be less seriously affected with the disease, they +strove to increase that which flowed from the glands of the mouth by +fixing a gag in the jaws, and keeping it there for several hours. This +measure seemed so efficacious that a decree from the Parlement de Rouen, +issued on the 13th of March, 1745, ordered the application of a gag, or +bit, for three hours every day, to the cattle under treatment. + +In the third period, they sought to overcome the wasting of strength in +the system by means of tonic and nutritious drinks, decoctions of +centaury, Jesuit's bark, juniper berries, &c. They likewise administered +emollient clysters if the evacuations were bloody. + +Moreover, they placed two or three setons, principally in the dewlap, in +order to obey the signs and indications of nature--_quo natura vergit, +eo ducendum_; as a salutary and critical eruption of the skin was at +that period forcing its way. These setons were kept open with a mixture +of turpentine and yolks of egg, for the purpose of encouraging the +secretion. The purulent or emphysematous tumours were cut. + +But whatever means might be employed, almost all the cattle perished, +and the few and rare recoveries only afforded the pessimists the +satisfaction of claiming the merit of them for themselves. It was +remarked, besides, that the fattest beasts were the least able to resist +the effects of the distemper. + +It is hardly necessary to say, that during the whole course of the +treatment, great care was taken to keep both the stables and the cattle +in a perfect state of cleanliness. + +The convalescence of those animals which were cured was invariably long, +and required great attention as to their food and hygienic treatment. +Solid substances, roots, and forage were withheld until rumination +revived; and it was only after several days of encouraging trials that +the recovered animal was suffered at last to feed all day in the field, +according to his pleasure. + +Such, then, was that formidable epizootia which, in the middle of the +eighteenth century, swept away upwards of six millions of horned cattle, +and which occasioned a loss to Europe exceeding fifty millions +sterling--perhaps we might say a hundred millions--for other domestic +animals, sheep, horses, &c. (as generally happens in cases of +epizootia), had likewise suffered, in different degrees, from the +various complaints arising from inclement seasons. + +It was certainly necessary to our purpose that we should have taken this +retrospective view of the cattle disease, and it will afford us a +valuable guide for the future. We may now content ourselves with +bringing together the different annals in the chain of time which +elapsed between Layard's treatise, which was published in 1757, and the +present day. This chain of time amounts to 108 years. + + +V. + +The typhus of Horned Cattle, which had shown itself in a manner +permanent, sometimes raging at one part of the globe, sometimes at +another, could not, under the unaltered conditions by which it had been +generated, suspend its ravages; and though, thanks to her isolated +position, England may be less exposed to it than other countries, it is, +however, necessary to take note of what may serve for our instruction in +the several epizootics which will pass under our view. + +Medical writers relate that contagious typhus broke out several times in +Holland during the years 1768, 1769, and 1770; it also appeared in +French Flanders in 1771, in Hainault in 1773. In France one particular +spot was, at this period, completely rendered intact by drawing a +sanitary fence about its limits, and bestowing on the cattle particular +hygienic attention as a safeguard. The stables of these animals were +washed, cleansed, and fumigated; spring water was given them to drink, +their food was chosen with care, and a certain quantity of salt was +mixed with it. + +In 1774, Holland, a cold and damp country, was once more invaded by the +scourge; and the Government offered in vain a reward of 80,000 florins +to any one who should discover the preventive or specific remedy for the +disease. + +The typhus which, at that epoch, had likewise broken out again in the +south of France, threatened to become an abiding peril to the wealth of +nations. Two French authors, Vicq d'Azyr and Paulet, betook themselves +earnestly to the task of collecting every document which up to that time +had been published on the successive visitations of the malady, and of +offering the means of preventing it. Their intention was unquestionably +laudable, but the time for obtaining such a result had not yet arrived; +besides which, these two writers, whatever may have been their desert, +were not equal to an achievement of this character. They belonged, +indeed, to that order of men who look upon the cultivation of science +solely as a step to personal distinction. + +Vicq d'Azyr himself was but twenty-five years old when he issued, in +1775, his work, entitled, "Expose des Moyens curatifs et preservatifs +qui peuvent etre employes contre les Maladies des Betes a Cornes." We +should deceive ourselves if we expected to find in this exposition +anything but an interesting compilation of the works already published. + +Paulet's treatise appeared likewise in 1775, under the title, +"Recherches historiques et physiques sur les Maladies epizootiques, avec +les Moyens d'y remedier dans tous les Cas, publiees _par ordre du Roi_." +Paris. Two volumes. + +After reading and reflecting on this title, as servile as it is +arrogant, I might have dispensed with all examination of the work. A +scientific man, whilst in the pursuit of truth, takes orders from +nobody, not even from kings. Paulet, therefore, writing _by order_, +could only produce a work of mediocrity, and such is incontestably the +degree of value of his two volumes, forming, as they do, a fastidious +dissertation of epizootics in general, and of those relating to cattle +in particular. + +The works of Paulet and Vicq d'Azyr, written at the same time, not being +the labour of men practising the medical art, are on a level as to the +notions which they have handed down to us; but that of Vicq d'Azyr +being the better of the two, we shall extract therefrom what may chiefly +interest us. + +Vicq d'Azyr relates the history of the epizootics, and expatiates on the +original cause of the typhus in horned cattle, and on its nature. The +passages in which he treats of its mode of propagation and its +treatment, are the most deserving of our notice. + +He says, that he tried to no purpose to communicate the disease a second +time to animals which had been fortunate enough to get cured. + +That cows covered with the fresh skins stripped from dead cattle, +victims to the distemper, did not contract it. + +That infected clothes which had been worn by men who had served in +hospitals where cattle were under treatment, having been laid on the +backs of several beasts in sound health, were found to transmit the +distemper in three cases out of six. + +That the gases expelled from the intestines, received into a bladder +ball, and let out under the noses of healthy cattle, have communicated +the disease to them, after ten or fifteen days of latent incubation; +and that the same gases being mixed with their drink, have also +propagated the contagion. + +That frictions, with the hands impregnated with virus, having been made +over the skin, did not produce any ill effects. + +That some oxen which had been designedly placed for a few hours among +sick animals, have afterwards been seized with the distemper. + +That a calf which had been placed in a stall containing some oxen +grievously affected, but which calf had a basket beneath its nose filled +with aromatic herbs, withstood the contagion. + +That cowsheds which had been partially cleansed and fumigated, +transmitted the disease to other cattle, even several months after they +had been vacated. + +Finally, he mentions the experiments of inoculation made by Lay and in +England, but not understanding their aim and capacity, he adds, that +inoculation does not seem to him of any use, since the inoculated +animals all died. Yet he quotes the encouraging results obtained by +Camper in Holland, who, out of 112 inoculated cattle, saved 41; and +those of Koopman, who, out of 94, cured 45 by this very inoculation. + +He reminds us that the cattle typhus is an abiding disease in Hungary +and Russia, where the beasts having bad water to drink, can only be +protected by a constant use of marine salt (_sel gemme_); but being +deprived of this salt, when they go great distances to be sold, and +being exposed to extreme fatigue and privations, the typhus then spreads +among them. He likewise tells us that Hungary and Dalmatia, which used +to supply the markets of Italy with butcher's meat, were obliged to give +up sending any cattle there, the Italians having firmly refused to +purchase the same at any price whatever. + +As regards treatment, the advice which Vicq d'Azyr gives to +agriculturists, is mostly borrowed from the authors who have written on +the great epizootics of 1711, and 1745 to 1755. Thus, he advises them to +give as drinks in the first stage, water whitened with meal and nitred; +to purge the animals with linseed oil; even to make scarifications on +the skin, and to keep up the suppuration with turpentine; to make the +animals inhale six times a day vapours seasoned with vinegar; to wrap +them over with woollen cloths; to bleed them once or twice; to +administer to them, when diarrhoea shows itself, a beverage containing +wormwood, quinine, and diascordium; to cut open the tumours containing +pus or air, etc. + +It is, as is seen, the same treatment as that quoted above; he +guarantees its success, and supports his views by the authority of Van +Swieten and Huxan. + +Van Swieten, however, had somewhat modified the treatment, by the +predominance which he allowed to acids; and this course seemed to him to +be only reasonable with respect to animals whose sick humours contain an +excess of alkali. + +Vicq d'Azyr fixed his attention on the means of prevention, the most +effectual of which, in his opinion, was to slaughter every animal which +had either sickened, or had been exposed to the influence of the +contagion; and as he insisted that the authorities had no measures to +keep in this matter of public interest, he made it a principle that the +government was bound to compensate the cattle proprietors whose animals +had to be killed--the more so, said he, that the crafty husbandmen would +never come forward and freely declare the invalidity of their cattle, +unless some indemnity were held out to them, which they would look upon +as a sort of equivalent for the benefits they had expected by cutting +them up and selling them as the food of man. + +The doctors of the period, scenting in Vicq d'Azyr a dangerous +competitor, considered the advice of exterminating the diseased cattle +as an _ingenious means of curing_ them, and as the author's age and +experience gave warrant for this satirical tone of discussion, the +public joined them in laughing at him. + +The epizootic typhus, if not so destructive, was at least as frequent in +the early part of the nineteenth century, as it had been during the +eighteenth. The armies during the wars of united Europe against the +French Republic and Empire, found it constantly in their train. Nor +could it be otherwise, the two leading causes of its prevalence being at +hand. For on one hand there was the transit of large herds from the +steppes of Hungary, and on the other the wretched hygienic conditions +amidst which the cattle had to live in the campaigning armies. + +Many books have been published of late years on the diseases of cattle, +in France and Germany; and several distinguished English veterinary +surgeons, especially Professor Simonds, have also devoted their +attention to the same subject. In the second part of this work, we shall +have occasion to refer to their labours. + +In France, Renault, Delafond, d'Arboval, Gelle, whose works enjoy a +deserved reputation, have discussed the subject of the origin of this +disease. + +Renault asserts that the disease has but one single focus, the steppes +of Russia and Hungary. The epizootics of Asia, Africa, and South America +are caused, he considers, by the importation of animals to those +countries. It is thus that he explains the epizootia which, under the +name of Delombodera, devastated the American Republics in 1832, and that +which, in 1841, appeared in Egypt. Renault thinks that neither the long +transit, nor the filthy state of the markets, nor the most wretched +feeding, are sufficient to account for contagious typhus among cattle; +that in addition to these causes, it still requires, in order to produce +and generate it among animals, a predisposition, and a special aptitude, +such as, hitherto at least, do not appear to have been witnessed except +in the progeny of the steppes. + +The other professors of his fraternity have submitted arguments to him, +which to us seem very rational; and we will endeavour to do justice to +them when we discuss the origin of the typhus which at this moment is +afflicting England. + + +VI. + +These historical dissertations and speculations on the subject of the +bovine epizootia certainly deserve to draw the attention of all who feel +an interest in the malady; but how insignificant they are compared with +the concluding facts which I have still to mention, before I at length +address myself to the consideration of the epizootia which is now +consuming our herds! + +The indisputable fact that so terrible a distemper as this typhus had +fixed itself permanently in Russia, and that it was causing incalculable +losses to the lordly proprietors of the steppes, as well as to the +government, roused them at last from their indifference. Then, indeed, +they urged the veterinary doctors to adopt some energetic means to +arrest the long duration of the scourge, and we must admit to their +honour, that various experiments which were tried for the purpose of +preventing the evil, have been crowned with complete success. Any one +may ascertain the fact by referring to the _Journal Magazin_ of Berlin, +in which the learned Professor Jessen of Dorpat has explained the +results of these important experiments. + +The Russian veterinarians having observed that the oxen which had been +cured of the typhus could mingle with impunity with the infected herds, +conceived the idea of communicating the complaint to sound cattle by +means of inoculation, and thereby to shield them from the contagion. + +The first experiments in the inoculation of _Tchouma_ or cattle typhus, +were made in the year 1853, by order of the government, in the +neighbourhood of Odessa, at the Heridin farm, by Professor Jessen. + +The first inoculative attempts were very fatal; they caused the death of +all the inoculated animals. But it was soon perceived that these +grievous results, far from prejudicing the theory, really confirmed it; +and that the virus, attenuated in its toxical properties, would prove as +effectual as was expected. And truly, in 1854 and 1855, at the Dorpat +establishment, the inoculations made with a better selected virus +afforded results less disastrous. At Kozau they were still more +satisfactory. In fine, passing from experiment to experiment, they +arrived at the conclusion that it was necessary to inoculate several +heads of cattle, the one after the other, without having recourse to any +other virus than the first inoculated, so that they might thereby obtain +virus of the 2nd, 3rd, 4th, 5th, and up to the 10th generation. The +virus thus attenuated in its morbid effects answered at length every +experiment, and oxen thus inoculated could mingle with impunity with +diseased cattle. + +At the veterinary establishment of Chalkoff they inoculated, during +eight meetings, 1059 animals with virus of the 3rd generation, and the +results were as satisfactory as could be wished for, only 60 animals +having sunk under the effects of this preventive operation. + +The inoculations made in 1857 and 1858 on an estate belonging to the +Duchess Helena, at Karlowska, in the government of Pultawa, and +conducted by the veterinarian Raussels, likewise afforded the most +satisfactory results. + +Professor Jessen thinks it certain, that beasts born of cows which have +been afflicted with contagious typhus do not contract the disease. He +maintains that Europe may be preserved from this frightful scourge, by +taking care that no cattle be exported from the steppes of Russia save +those which have had the distemper either naturally or by inoculation, +and he is striving to propagate this opinion, and to render it +practical, by having all the cattle inoculated, without exception. + +It is deeply to be regretted that counsels so prudent have not been +heeded in the 47 governments which, out of the 53 possessed by Russia, +have generated the contagious typhus; for then it would not so +frequently have effected its passage into the neighbouring states, and +England most probably, would not now have to take up arms against its +fatal extension. + + +VII. + +We here conclude that part of our labour which includes the history of +this disease, and what we have been able to glean from those medical +writers, and others, who have given us the results of their experience. +It may have appeared somewhat protracted, but it has at least laid open +to the student the antecedent investigations of our predecessors, under +calamities of the same kind, but considerably more fatal than what has +yet been witnessed in Western Europe during our time. We have +disinterred and brought to light the forgotten works of conscientious +and competent men. Like Brunelleschi, the architect, we have sought, not +to invent a theory, but to recover a practice; and thus we have received +the observations and precious facts, and finally the preventive +treatment, of other men and other times, which had coped successfully +against the cattle disease when its ravages were infinitely greater. + +To resume, then: these inquiries (which we undertook without +anticipating so rich a harvest) have proved, and made evident-- + +That the contagious typhus afflicting horned cattle, has spread its +destructive principle over our globe ever since there have been animals +living on its surface. + +That from century to century, not to say from year to year, it has +carried its terrors amidst nations and peoples. + +That the remedial measures which had been taken and applied prior to the +middle of the eighteenth century, were utterly powerless either to cure +this disease or to prevent it. + +That at that period appeared two English physicians, men of remarkable +aptitude and penetration, one of whom, Malcolm Flemming, laid down in +theory the bases of a preventive treatment; whilst the other, Peter +Layard, applied this theory to practice, by inoculating sound and +healthy animals with the morbid virus of the typhus, in order to protect +them from the fatal effects of the contagion. + +That this all-important progress in medical experience, has been +absolutely forgotten; so much so, indeed, that the experiments of +inoculation, tried in Russia only ten or twelve years ago with perfect +success, do not seem to be connected by any link with those made in +England a century before, and that the invasion of the so-called +CATTLE PLAGUE in 1865 seemed to some men to have introduced a +new scourge, which men were not armed and prepared to meet--which they +were powerless to cure, or to stay in its progress. + +These inquiries, then, have proved, we think, that we are not so +helpless as we had imagined to resist the evil. But we cannot help +feeling, that we have laid bare in this exposition some most distressing +inferences concerning the human mind. For, in truth, can anything be +more deplorable, than thus to see the civilized nations of Europe +endure, from century to century, these reiterated outbreaks of cattle +typhus, and to see likewise that no man of sufficient energy and +independence has yet arisen to tell the truth fearlessly to the +governments and peoples, however painful that truth may be, and to +expose the futility of the measures hitherto employed to arrest the +scourge? + +And, on the other hand, is it not most afflicting to see discoveries of +indisputable value buried out of view, submerged in public libraries, +utterly unknown and forgotten, like their authors, to such a degree, +that the distemper which they have made known in its entirety, and which +is as old as the world itself, seems to us almost new in 1865? + +God send, that these cruel trials and severe lessons which the past has +bequeathed to us may teach us something for our benefit! May the +irresistible might which is derived from the auspicious union of capital +and intelligence supersede the vain and flimsy efforts of isolated +energy! May the government, which lavishes hundreds of millions upon the +destructive engines of war, devote some portion of its ample means to +the study of hereditary infections and contagious diseases! For these +fatal epidemics decimate men as well as cattle, and we may at least ward +off from our children the desolating disease which at present afflicts +ourselves. + +We possess already every requisite means to protect ourselves from the +formidable visitation of these diseases: we have science; we have the +men who cultivate and teach it; we have the experience of the past +added to our own. To-day, we are called upon to resist the baleful +effects of cattle typhus; but another epizootia may come to-morrow, and +strike our horses and our sheep--those domestic animals which constitute +our most precious possession. The cholera hovers about us. If we do +nothing, if we talk and debate instead of acting, these scourges will +come upon us on a sudden, and find us quite as helpless as ever to +resist their sway. + +These palpable truths deserve to be further developed, and will be +treated more copiously at the end of this book. They will constitute the +complement of our work, necessarily written in haste, since the danger +we had to expose was itself so urgent and alarming. + +FOOTNOTES: + +[A] To assist the researches of other inquirers on this vital subject, +now so generally interesting, we may add, that the cattle treatises +already referred to--of Malcolm Flemming and Peter Layard--are to be +found in the Library of the British Museum, bound together in a single +volume, which is certainly worth ten times its weight in gold. It +contains, indeed, eight different opuscula, all relating to cattle +complaints, which scientific students may consult with real +gratification. I will here transcribe the titles of the most important +of these treatises, the pregnant expositions of the two English +physicians above-named. + +That of Malcolm Flemming: + +"A Proposal, in order to Diminish the Progress of the Distemper among +the Horned Cattle, supported by Facts. London, 1755." + +That of Peter Layard: + +"An Essay on the Nature, Cause, and Cure of the Contagious Distemper +among the Horned Cattle in these Kingdoms. London, 1757." + +A great many accounts, treatises, and expositions on the same subject +appeared at the same time in France, Holland, Denmark, and Switzerland. +One, which appeared in the last of these countries, is entitled: + +"Reflexions sur la Maladie du Gros Betail, par la Societe des Medecius +de Geneve. 1756." + + + + +SECOND PART. + +This Part is divided, as already stated, into four chapters. + + + + +CHAPTER I. + +_On Typhous Diseases in general, and the Typhus which affects the Ox in +particular._ + + +By following the example of those authors who have described the +contagious typhus of the ox, we might proceed at once to explain its +symptoms, and go directly to our purpose; but, by taking this hasty +course, we should expose ourselves to be imperfectly understood by the +majority of our readers, and to leave certain doubts in the minds of +physicians as to the nature of the disease and the propriety of its +treatment. + +All animals, including man himself, are born with a predisposition and +liability to contract a certain number of contagious febrile diseases; +they bear in a manner a certain number of physiological elements, which +might be called latent germs, and which, under given conditions, become +the leaven of these diseases. This must, indeed, be the case, since +after these disorders have been once developed those who have been cured +of them are not apt to contract them again, the morbid developments +having destroyed that natural aptitude which had previously existed to +undergo the morbid action of the contagious virus. These diseases are +not numerous; they constitute a very distinct class, and the same laws, +which regulate the phenomena in one of them are applicable to all the +rest. + +These diseases exhibit the following characteristics: 1st, a period of +incubation, during which the whole economy, more particularly the blood +and humours, experience very important changes and modifications; 2nd, a +febrile state, which varies in its continuous or intermittent types, and +in its intensity, according to the species of the animals, and which +proceeds from the alteration of the blood; 3rd, a revulsion at once +toxical and congestive towards the nervous centre, inducing _stupor_; +4th, a flux of mucus from the mouth and chest; 5th, a more intense, +congestive, and inflammatory flux or discharge from the external or +internal teguments--the skin or the mucous membrane of the digestive +channels; 6th, a period of adynamia and dejection, with a tendency, in +some cases, to a critical or salutary rejection of the morbid matter by +the development of tumours or abscesses in the skin; 7th, they are at +once infectious and contagious, epizootic or epidemic; that is to say, +they are transmitted in different degrees by contact, by inoculation, +and at a distance by the means of vitiated air; 8th, finally--and this +is their leading characteristic--_they are not subject to recurrence_, +each individual that has once been affected, losing in general all +aptitude to contract the disease a second time. + +This last characteristic, when well understood, ought in reason to +induce us to have recourse to the preventive treatment, and such has +been the case with respect to the most virulent amongst them--small-pox +and the typhus of the ox. + +Prompted by these principles, which are as logical and fixed as any +mathematical deduction, I suggested in 1855 that inoculation should be +applied in typhoid fever, which is nothing else but the equivalent of +intestinal small-pox, in order to prevent the disease in men. But if the +simplest truth sometimes requires a contest of ages before it is heard +and understood, I could not hope to fix attention on a fact which might +be taken as problematical. I felt that I was outrunning time, and that I +should neither be heard nor understood; and so it has proved. + +Be that as it may, these typhous diseases have, as is seen, their laws +and foreseen development. They attack animals generally, but chiefly +herbivorous animals, endowed, as we have shown in the first part, with a +vital resistance which is, relatively speaking, very inconsiderable. + +These febrile typhous diseases (whether their development is caused by a +spontaneous morbid action in the patient or by an evident contagion), +have a period of incubation during which the vital strength undergoes +latent morbid modifications, though not sufficient to indicate, save in +times of epizootics and epidemics, the particular form which is about to +reveal its symptoms in the course of a few days. This period of +incubation being over, the mouth and chest become affected, and fever +declares itself; and then the _materies morbi_, which is to become the +special and dominant characteristic of the distemper, is directed either +to the skin, or to the digestive mucous membrane. In the first case, we +see evidence of exanthematic diseases, which present only the lightest +forms of detersive disorders, such as measles, scarlatina, or that more +serious one, from its pustulous form, the small-pox. In the second case, +the elimination takes place from the intestinal canal, and then we see +produced in animals, as well as in men, the typhous diseases: that is to +say, the typhoid fever--a pustulous and ulcerous malady of the +intestines--or the common typhus of the hospitals, prisons, and +campaigning armies; and again, in animals, there is also the typhus of +the steppes, of the marshes, &c. + +The Eastern pestilence, the plague of Rome in the age of Antoninus and +the plague of Athens, which might have given to Hippocrates the right +of treating with Artaxerxes as one potentate treats with another, ought +perhaps to be classed among those typhuses not subject to recurrence. + +As for the _cholera_, it seems to be a contagious and epidemic disorder, +of a distinct and particular kind. We are ignorant of its essential +cause, its nature, and its mode of treatment; and although it has +prevailed in every age, and even frequently of late years, it will +always, by reason of the strange formation of our medical institutions, +find us as weak and defenceless to resist its attack as we have ever +been. + +If we have been properly understood, typhous diseases are, above all, +general febrile affections. At one time the _materies morbi_, or +discharge, affects the skin; at another, the digestive mucous membrane. +When it acts upon the skin, as clinical observation shows, there is +sometimes a sort of hesitation in the eruptive process; people wonder +what disease is coming forth; the eruption wavers in the form it will +assume, till at length its real character is determined. The same +uncertainty prevails when the intestines are affected. Sometimes the +exanthema is merely the equivalent of simple measles or scarlatina of +the intestinal mucous membrane, and many typhoid fevers of short +continuance are nothing else in their nature. The same occurs in common +typhuses. Sometimes the local affection proceeds as far as pustulous +eruption, sometimes only to exanthematic rubefaction; hence the various +alterations which we have witnessed in the intestines of cattle killed +in our presence at the slaughter-houses of the Metropolitan Market, and +which we ourselves dissected. The experienced Professor Bouley, from the +Ecole Veterinaire of Alfort, near Paris, whose visit must have been +beneficial to England, clearly recognised in an ox which was slaughtered +and dissected at the Metropolitan Market, the genuine pustule of typhoid +fever. But in most cases, as we shall show, it is the other forms which +prevail. + +We make these observations in order to anticipate the objections of +those reasoners who, being more influenced and guided by the local facts +and by the symptoms, than by the general phenomena of comparative +pathology, might argue that such or such fact is opposed to our +doctrine. + +In a word, then, typhous diseases have their types; but the living being +is subjected to so many different influences, hereditary, idiosyncratic, +climataic, hygienic, &c., that by the side of one subject going through +the course of morbid phenomena with fatal regularity, another may be +seen in which such or such functional derangement is readily +distinguished. Thus in some animals, predisposed thereto by prior +disorders, the morbid action originally propelled towards the channels +of respiration will continue to be most salient; and after dissection +the lungs will be congested and emphysematous, and the intestines +relatively but scarcely altered. The animal, indeed, though bordering on +typhus, will sink under the effect of functional derangement in the +breathing passages. In others, by the influence of some particular +predisposing cause, disorders of the nervous centres will be signalized; +a cerebral and spinal pains will be intolerable, delirium will quickly +ensue, and the asphyxiated patient, if a man, will succumb in the course +of a few days; or if an ox, he will be wild and ungovernable, and then +fall as if thunderstruck, fastened to his stall. Finally, in other +cases, these first two phases of the distemper will not prove fatal, the +intestinal injuries will pursue their course, and the affected animals +will not die until the third period. + +As we have seen, the morbid phenomena may be different, although the +affection continues the same; the typhoid fever or the typhus being +nevertheless the essential disease which prevails. + +These generalities, to some readers, may appear irrelevant, but let them +not be mistaken; they have a claim to our notice, and are really +important. They show, indeed, that independent of the preventive +treatment, which is an absolute rule in the case of virulent, +contagious, and non-recurring diseases, the treatment of the disease +itself, when it has declared itself, and when it pursues its course, +cannot be the same for every patient; and that, moreover, this treatment +must vary in the different phases of the disease, as physicians and +veterinarians are well aware. + +These generalities, likewise, explain the various diseases--viz., those +in which the animals blend together the typhous and exanthematic +diseases. The measles and the scarlet fever, affecting the external or +internal membranes, are like the first steps of these maladies; they are +generally slight, and we have but to watch over the progress of the +symptoms, and to assist nature, which, with few exceptions, brings all +things to a favourable issue. + +These disorders, which are relatively slight and do not provoke in the +economy any of those changes which in some sort transform the +constitution, are not absolutely proof against relapse. They lead us +rationally and by degrees to the more infectious and contagious +diseases, to the common typhus; therefore it is unnecessary to apply the +preventive treatment to them, that being exclusively reserved for the +latter. + +Let it then be well understood, that the typhus of the ox, the study of +which we are about to enter upon, may vary in its symptoms and +post-mortem appearances, without losing thereby the characteristic mark +which renders it a thoroughly distinct, and, in the present day, a +thoroughly well known distemper. + +Now that the reader possesses these general notions of the Contagious +Typhus, we shall be able to speak to him in a language which he will +understand, and give a definition which he will be able to judge and +appreciate. + +The typhus of the ox, then, is a _virulent, contagious, febrile, and +non-recurring disease, with stupor and derangement of the nervous, +respiratory, and digestive functions; leaving various changes in the +respective organs of these functions, and chiefly in the intestines_. + +This new definition seems to us to be more faithful and just than those +hitherto given; and this, if needed, we could demonstrate. + +I do not disguise from myself that some of the opinions expressed in +these generalities may, at first sight, appear strange and liable to +objection. Thus, it may be argued that inoculation as a preventive +treatment of typhous maladies is far from being a general law, +applicable to every case; since in Russia, for instance, where this +inoculation is practised every day, it completely fails in certain +foreign herds, and they die of the consequences of the operation; and +that this, therefore, might happen in England. + +To these objections we would reply, first, as regards the novelty of +opinions expressed, that we have taken up the pen, because we had to +write something different from what has already been published in known +works, otherwise it would have been our duty to remain silent; and +secondly, as regards the inefficacy of inoculation, that organic and +vital phenomena have their principles and their laws, which are fixed +and invincible, from which it is reasonable to deduce consequences and +positive rules of conduct, which cannot yield to superannuated opinions +or imperfectly executed experiments. To institute experiments indeed +under the rigorous conditions of a logical and irrefutable +demonstration, is not so easy a matter as may generally be thought. + +For our part, the principles deduced from strict observation are the +basis on which we build, and if it so chance that we are baffled in our +experiments we vary them indefinitely; and if still we are deceived in +our hopes, we ascribe the miscarriage to our impotence, to inadequate +means, and to the defective instruments which the physical and chemical +sciences, still in their cradle as regards organic matter, supply for +our use. Above all, we wish it to be remembered--"_Scribo nec ficta, nec +picta, sed quae ratio, sensus, et experientia docent._" + + + + +CHAPTER II. + +_The Origin and Causes of the Ox Typhus._ + + +I. + +I have drawn my conclusions as to the preventive treatment of typhus in +the ox, from the knowledge I had acquired of its morbid phenomena, its +nature, and its non-recurrence; and it is a logical deduction quite as +accurate as could be the result of a syllogism. The study of the origin +of this typhus, and of the causes by which it is generated and spread +abroad, will supply us with additional arguments to sustain this +deduction, as well as those signs and indications which are the very +foundation of curative treatment. The description of the disease will +contribute to the same result; for the rational treatment of a distemper +can be derived only from a knowledge of all the phenomena which occasion +it, of the functional derangements, and of the alterations observed in +bodies after death. + +I wish particularly to say at once, in entering upon the subject of +etiology, that the special works which treat of it contain precise +information as to the causes and origin of the typhus in horned cattle; +and that the chief organs of the press in every country--those ephemeral +encyclopaedias in which unfortunately so much vital force and +intelligence are dissipated--have published articles of the highest +interest on this subject. It would be physically impossible for me to +begin again a bibliographical labour similar to the one exhibited in the +First Part, in order to afford due justice to each of these public +writers, who have met the epizootia on the confines of their country and +fought hand to hand with it. This work is not susceptible of so much +enlargement. Let it be well understood, that I claim no other merit than +that of discussing these questions of etiology, in that order and with +that common sense which fix ideas firmly in the mind--which, if I may +use the term, _photograph_ them on those parts of the brain allotted to +the memory and judgment; also of drawing from known and admitted facts +more rational and practical conclusions than those which have been +current up to the present time. + +Much has been already said and argued on the origin of the contagious +typhus which affects the ox; some adhering exclusively to the special +conditions observable in the breed of those oxen which are reared and +fed on the steppes of Russia and Hungary; others, more reasonably, as it +seems to us, ascribing it to the hygienic conditions generally, that is +to say, to the climate, the season, the feeding, &c., &c., amidst which +these animals are living. + +All these discussions upon what has been said and argued on this subject +have been very useful. For, had it been rigidly proved that the oxen of +the steppes, by some peculiar organization, carry within them those +germs or physiological elements which at given times become the leaven +of the distemper, and, at a subsequent period, the elements of the +contagion, then, indeed, a fact of capital importance and prominent +authority would have been established, and the attention of all men +interested in these inquiries would have been exclusively concentrated +on that particular race of animals and on those countries smitten with +the curse, in order to arrest and confine the disease within its one and +only focus. + +The supporters of this theory, concerning the first circumscribed origin +of the typhus, maintain that all the epizootics whose deplorable history +we have given in the first part of this work, have had no other +generative causes than the propagation of the complaint, born and +begotten on the banks of the Wolga and the Danube, and subsequently +conveyed to the different parts of the earth by the emigration of the +cattle. And in this manner, too, they have accounted for the appearance +of the typhus in South America, in Africa, and in Asia. + +Since this doctrine on the origin of the typhus has been conceived and +maintained by men of a high order of understanding, we must suppose that +they had been struck and convinced by important facts and serious +reasons; and as it would be unfair to oppose a plain denial to an +opinion now so generally adopted, we are bound to say in what manner +these authors justify their views, after which we shall endeavour to +refute them. + +The partisans of the circumscribed origin, who make it depend +exclusively on the peculiar organization of the race of the steppes, +have based their argument, peremptory and unanswerable as they imagine, +on the prime fact, that it has always been possible to trace the +diffusion of the typhus in a given country, to some sick animal of the +steppes conveyed to that kingdom. In this manner it is, that they +explain the generation of the epizootics which have so frequently wasted +the continent of Europe. On whatever point of the globe they may appear, +this, and only this, is the source of their existence. The isolated +position of Great Britain is made to support their arguments. "Behold," +they exclaim, "Great Britain, which, thanks to its surrounding seas, has +escaped most of the epizootics which have desolated France and Germany +during the early part of the nineteenth century." Nay, more, the present +visitation of the distemper is also seized upon to sustain their theory, +since certain oxen, natives of the steppes, appear to have imported it +into London. + +We must add, that nothing is wanting in order to prove this assertion; +for they relate with perfect regularity, and step by step, the course +taken by the contagion; they specify the time occupied on its passage, +and even the names of the infected vessels which have thus imported the +principle of the typhus. + +It must be admitted that all the facts thus stated are indisputable; we +acknowledge as true, that the bovine race of the steppes has conveyed +into other countries the contagious germs of the disease; we admit that +its dissemination may be thus accounted for. + +But to admit this fact, and to draw from it the conclusion that the +bovine race of the steppes alone is capable, by some particular and +distinct organization, of developing the original typhus of the ox, and +that this typhus has no other focus on the earth than the banks of the +Dnieper and the Don, does not appear to us a sound logical deduction. +And as, if this conclusion were positively recognised, we might see but +one side of the evil, and deduce very serious consequences therefrom, it +is necessary to receive these facts for what they are worth, and no +more. + +Let us first observe, that those writers who ascribe the contagious +typhus to the race of Southern Russia, do not take into consideration +the epizootics of this typhus, the account of which has been handed down +to us by the ancient authors of Greece and Rome; and that they refer +just as little to those which are quite as frequent in the republics of +South America as on the banks of the Dnieper. For even if we allow that +once, and only once, one of these epizootics may be traced to the +arrival of a ship containing oxen brought from the steppes, how, on the +other hand, can we believe that all other epizootics have had such a +fortuitous cause to generate it; consequently, the typhus, in these +cases, must have been locally developed and diffused among American +cattle? + +Moreover, we seek in vain for the reasons which would authorize us to +assign to the bovine race of the steppes a particular organization, +rendering it alone fit to engender the typhus. But let us grant for a +moment, that the Russian and Hungarian oxen constitute a peculiar race, +as their framework and the length of their horns would seem to imply; +this much being conceded, it still remains to be shown in what respect +their anatomical and physiological structure differs from that of other +animals to such an extent as to render them alone liable to originate +this fatal typhus. + +Oh! if it were true that the bovine race of the steppes alone could +engender the typhus! we would hail the fact with joy, and would show +without much exertion of reasoning that, in that case, we possessed not +only the means of preventing the disease by inoculating sound and +healthy cattle, but the far more important means of sweeping it for ever +from the earth, by at once exterminating that cursed race, smitten with +the original predisposition of this plague; and as, after all, the +murderous scourge of the typhus of the steppes has already cost, and may +perhaps continue to cost the various nations of the Old World millions +upon millions, they would feel that their most urgent interest would be +to come to an understanding (nor would the sacrifice be too much for +their resources) so as to destroy and extirpate the evil at its original +source. There would then be no difficulty in raising up a new breed of +cattle in those countries, by transporting to it those of other nations +free from the infection. + +But who does not understand that this heroic sacrifice would be +illusory, and that the foreign races, modified in time in this new +medium, would regenerate the typhus; so that the double sacrifice of +extermination and indemnity would have been made to no purpose? + +We wish we could adopt this hypothesis, so simple and so consolatory, of +the circumscribed origin of the typhus, and its exclusive propagation +through the race of the steppes; but our mind is altogether opposed to +that view, and for the following reasons, amongst others:-- + +If the bovine race of the steppes alone could produce the typhic virus, +by reason of a particular organization which is the prime condition of +its existence, _this race alone would of necessity be fit to receive its +taint_ by the influence of contagion. But if the other animals of the +same species, as unfortunately too surely happens, can receive the +principle of the disorder, develop the ailment, and die of its effects, +then the reasoning of our opponents is faulty from its source; and it +must be admitted that all horned cattle are apt to generate the typhic +virus in those countries which afford the conditions of its production, +and that this exclusive predisposition as it is called, attributed to +the race inhabiting the steppes, is simply a chimera. + +But arguments are seldom exhausted even to defend a bad cause, and it is +objected that the fact that all oxen may contract the typhus transmitted +by the contact of animals from one to another, does not prove that the +original predisposition is the same in every race; and they persist in +maintaining--1st, that the typhus of the steppes is alone able +originally to beget the disease; 2nd, that having thus begotten and +produced it, it becomes, after this organic conception, apt to be +transmitted to every animal, and fit to be assimilated with them. + +To these subtleties and argumentative refinements it would be as easy +for me to oppose abstract reasonings equally strong, as it would have +been for the Jansenists and Mollinists, had it so chanced that they had +been drawn into a debate on the origin and nature of the virus of the +plague which carried off Jansenius. But let us confine ourselves to +serious facts and conclude-- + +1st. That we have no proof of any anatomical and physiological +difference in the humours or in the blood--that is to say, in the +organic, intimate, and biological elements of the individuals which +collectively constitute the bovine species. + +2nd. That we have a right to believe, that all horned cattle are apt to +develop the typhic virus when they are placed within the conditions +required for that effect--that is to say, when they are exposed to the +special morbific causes which form its condition _sine qua non_, and +which are met with on the banks of those great rivers which water +Southern Russia and Hungary, in Africa, on the banks of the Nile, in +South America, on the margins of the lakes, and in what are called hot +climates, &c. + + +II. + +But if the origin of the typhus cannot exclusively depend on the +peculiar organization of certain individuals of the bovine species, we +must inquire after and search for the real causes which produce it. + +We have explained already, in the First Part, what alterations organic +matter undergoes in general, when accidental causes happen to modify its +organic elements; and we have pointed out the fact, that of all living +creatures herbivorous animals were those that offered the least vital +resistance to the causes of disease and destruction. + +This unquestionable fact being taken for granted, let us now consider +under what conditions live the multitudinous herds of horned cattle +which in Russia and in South America are reared and supported solely for +the produce of their flesh, and sometimes, too, for that of their hides. + +The great breeders and proprietors fix the number of their heads of +cattle according and in proportion to the quantity of the pastures, but +like other men, they mortgage the future for their benefit without +making due allowance for accidents or extreme changes of weather, as +when years of unusual drought succeed those of heavy rain; so that these +herds, by the single fact of these extreme fluctuations in the degrees +of temperature, are exposed to a multiplicity of causes productive of +disease. The same nature which generates life and health generates +disease and dissolution, and when the former are neglected the latter +will prevail. + +In the prosperous and favoured countries of the temperate zone, such as +England and France, these extreme variations in the seasons, which are +always the cause of a deficiency or alteration in the production of +fodder, are equally the cause of the numerous epizootics which attack +all the herbivorous species, and particularly those to which oxen fall +victims, such as the tumourous typhus (_le typhus charbonneux_), the +so-called aphthous fever, the contagious peripneumonia (which is not +liable to return and is prevented by inoculation), parasitical cutaneous +disease. + +But in less favoured countries, in those which are damp, argillaceous, +swampy, inundated by the overflows of their lakes and rivers, or by the +reflux of the sea, there is deposited a slimy or brackish water, which a +temporary torrid heat afterwards causes to ferment; and then a +superabundance of life, a teeming vegetation, springs up in all +directions. In the midst of this swarming vitality live and thrive an +infinity of worms, maggots, animalculae, insects, mollusca, fish, +reptiles, birds, &c.; and here, too, all these creatures die and decay, +when this slime, the prolific source of generations which we might look +upon as spontaneous, begins to dry up and disintegrate. Then from these +organic vegetable and animal matters, in a state of decomposition, +escape those deleterious gases, such as hydrogen, carbonic oxide, +nitrogen, carbonic acid, sulphuretted hydrogen, and even phosphoretted +hydrogen. + +Often to all these causes of infection are added myriads of +grasshoppers, which cover the ground, where they die, aggravating the +mass of pestiferous vapour which fills the atmosphere. Finally, the +water which slakes the thirst of the herds of cattle is corrupted; the +plants on which they feed distil poisons; the air, the water, and the +plants, carry within them a principle of venom and death. After this, +how can we be surprised if this flood of putrid emanations is +transformed into a contagious typhic virus, whose subtle and +pestilential effluvia are conveyed by the ox to considerable distances? + +In fine, let us recapitulate in our minds all the causes of destruction +to which these passive creatures are exposed, and we shall acknowledge +that there is no necessity to attribute to them a peculiar organization +in order to understand the development of the typhus, which, at a given +moment, cuts them all off; and that in the deltas of the different +countries, as well in Asia, Africa, and America, as in Europe, are to be +found those conditions of infectious disease which we have described. In +these causes, and only in these causes, or in those which resemble them, +will rational men seek for the principle of the contagious typhus in the +bovine race. + +Moreover, who is there who does not understand that what is true with +regard to cholera is likewise applicable to this contagious typhus? The +cholera, for causes analogous to these, subject to the particular state +of the soil, is generated, not exclusively, it is true, but most +frequently, on the banks of the Ganges, in the same manner as the +contagious typhus is developed in certain countries where its natural +focus is found. + +The race of animals which exists on this deadly and destructive soil is +an instrument of incubation for typhus, not in consequence of their +peculiar structure, but because the conditions under which they live +condemn them to this fate. + + +III. + +Now the breeding of cattle, and the feeding and fattening of them for +the market, constitute a branch of industry--a great interest. They all +have to be removed, conveyed to various distances, and sold; so that +this traffic becomes a new cause to be added to all those which foster, +develop and propagate the distemper. + +In prosperous times, when the seasons, conformably with our wishes, have +pursued a course which we call regular (for we are fain to believe that +the planets turn on their axes on our account), and when the cattle find +the ground covered with rich pastures, and limpid streams--conditions +which are eminently favourable in themselves, though in Hungary it is +necessary to add gum, salt, mineral water, and arsenic acid, before the +health of these animals is satisfactory,--then the cattle breeders make +their sordid calculations, and select the heads of cattle intended for +sale. + +With animals, as with man, health is but relative, not absolute; the +healthiest in appearance often bearing within its frame the fatal +principle of no distant death. Fatness not being by any means a sure +sign of vital strength, many of these cumbersome beasts, though +seemingly in good and sound condition, contain in their systems, in +various stages of incubation, the tainted leaven of contagious +affections, such as peripneumonia, or even the typhus itself. + +But, regardless of this liability, their sale and migration are resolved +upon at length. Hitherto these harmless creatures have lived in the most +perfect stillness and retirement. Their calm, monotonous life has been +as regular as the course of time; never by a single pulsation have their +hearts exceeded the wonted number per minute; they are all gifted with a +nervous sensibility of which the vulgar have no notion. Some favoured +few have felt the sympathy of friendship for the herdsman who tended +them, and for the companions with which they fed. They have been leaders +of their own herd, they have marched at their head; they have given the +signal when to seek shelter beneath the trees, or when to repair to the +brook. They have loved the fields amidst which they have grown and +thriven. Some of them, reared and fed beneath the domestic thatch, were +grateful for the care they had received; their master was endeared to +them, they would run to meet his coming, answer to their name, and lick +his hand with fondness. + +And it is the course of this tranquil, this happy existence, that is +about to be broken abruptly. It is this creature, the pattern of +gentleness and goodness, that we are going to treat like a heap of +insensible and inert matter--which we are going to subject to +unutterable torture! + +And now, indeed, these creatures are all at once handed over to the +savage guidance, to the thongs and cudgels, of a hind, whose cruelty +keeps pace with his stolid ignorance, and who abets his dogs to quicken +their course to the neighbouring market. From this moment, half-fed and +athirst, these poor animals are forced to make long journeys afoot; or +since the construction of railways, to be heaped together confusedly in +a locomotive pen. There, the shaking, the sudden starts, the friction of +five hundred wheels on the rails, the horrid snorting of the engines, +alarm and terrify them to such a degree as to turn the whole mass of +their blood. + +In such a state of vital prostration or feverish excitement, entire +herds are carried to the public markets or to annual fairs with other +animals, and nearly all sent to the shambles. But some amongst them are +reserved for another fate. The females, for instance, are set apart to +serve as milch cows; and in this manner they carry with them into the +cowsheds, wherein they are received, the taint of those contagious +distempers, the germs of which lay concealed in their frames, or which +they have contracted from the companions of their journey. + +Some of these heads of cattle, starting from the steppes of Russia, have +to travel five hundred miles in an open cage, less cared for and +protected than bales of merchandise, exposed to the rain, to the heat +of the sun, to sudden changes of temperature, to cold and cutting +draughts, increased by the rapid motion of the train;--these animals, +foundered, prostrate, panting with fever and torturing pains, still have +to undergo new trials, if they cross the sea. In this case, the wretched +victims are violently expelled from the locomotive, rocking sheds of the +railway; a leathern strap hanging from a crane lifts them into the air, +and lets them down into the mid-deck of a ship, where they are crowded +as closely together as possible, for here, too, space is very costly. +Finally, the vessel gets under way and ploughs the ocean; contrary winds +beat it about in every direction, and these poor creatures have to +endure a new kind of torture, accompanied by the intolerable pangs of +sea-sickness; and in this state it is that they alight on the British +soil, and are driven off to the different markets. + +It is useless to expatiate at length on the state of general derangement +and disease in which these oxen reach their final destination. Some +amongst them have endured for eight or nine days these unspeakable +tortures, without being sustained by nourishment--for no animal, when +his spirits forsake him, can assimilate his food amidst all this +physical suffering and so great a shock to his nervous system. + +Let us here declare that these animals, though removed from their +meadows with all the signs and appearances of sound health, at a time +when a fine season had been productive of abundance, and when no +epizootia was raging in the country which they have left, may +nevertheless bear within them the taint of contagious typhus; and let us +ask ourselves what must come to pass in those disastrous years when this +typhus prevails under the influence of those destructive causes which +were passed in review just now, and when the Russian and Hungarian +proprietors, eager to forestall an inevitable general calamity, hasten +to send off to Italy, France, Holland, Finland, or to the ports of +England, many animals already seized with typhus, and whose virus must +have acquired infectious properties still more intense and deadly under +the influence of the deep disquiet and commotion which the removal and +conveyance of these animals, under conditions so deplorable, must have +produced in their frames. + +Such are indeed the pernicious conditions in which oxen may be, and +often are, dispatched to England; and such appears to be the real cause +of the outbreak of the spreading epizootia which we witness at this +moment, and which has created so much alarm in so many counties of +England.[B] + + +IV. + +Let us now consider this contagious typhus in its destructive extension +over the British soil; let us study and examine the causes of its +diffusion as they pass under our notice. + +The mooted question of determining whether the cattle typhus was +originally imported from abroad, or whether it broke out spontaneously +in England, has been, and still is, a subject of dubious debate amongst +some professional men, amongst the leading writers of the public +journals, and also amongst agriculturists and farmers.[C] + +And, in truth, the propagation of the distemper is occasionally +witnessed under conditions so singular and striking, that it seems to +warrant and supply arguments for every conceivable opinion. + +When the disease was recognised and identified for the first time on the +24th of June, 1865, public opinion ascribed its appearance to contagion +arising from some diseased cows imported from Finland, and which, after +being exposed in the Islington Market on the 19th, were sold and removed +to the cowsheds of a breeder or dairyman. + +We may observe that, on hearing the intelligence of this sudden +invasion, the public mind, which is so excitable in England, did not +disguise the indignation it felt against foreign countries which had +been capable of contaminating an island so advantageously situated and +so well protected, and infecting her magnificent herds, exuberant with +health. But after a closer examination of the facts, and possibly +alarmed, at the serious consequences of a Continental blockade which +would deprive the United Kingdom, not of the entire twenty or thirty +thousand live stock, such as oxen, sheep, pigs, &c., which they receive +every week, but only of the eight or ten thousand head of cattle which +are landed weekly on their coasts to supply their markets, public +opinion was appeased. But, unfortunately, this national susceptibility +now took the opposite extreme; and the only causes it now saw were the +dirt and want of adequate ventilation in the metropolitan stables and +sheds; and to these causes it attributed, first the generation, and then +the propagation or diffusion of the malady; an opinion which appeared +all the more natural and reasonable, in that the oxen and cows of the +graziers were the first victims of the typhus. + +We all know how liable, among all nations, the public mind is to waver +and fluctuate, and how susceptible and open it is to new impressions +during fatal visitations and general calamities; nor can we feel the +least surprise at the uncertainty which has so long prevailed, and still +continues, as to the real causes of the introduction of the bovine +typhus in England. + +Let us therefore examine this question of etiology, and try to discover +what opinion ought to prevail. + +It is important to establish at once two material facts which seem to us +indisputable: + +1st. That the contagious typhus in cattle which is known to be permanent +in the southeast of Europe, actually existed there during the month of +June, 1865; 2nd, That some of the horned cattle, fed and reared in that +part of Europe, were transported to England, after having crossed +through Russia from south to north, in order to avoid passing through +Germany. + +As for the first of these facts, it is admitted and received, as might +easily be proved by reproducing the speeches and addresses delivered by +the veterinary doctors at the Congress now being held at Vienna, and at +which were present the men whose experience of this cattle distemper +gives them the highest authority--Hertwig, Jessen, Roell, Siegmund, +Gerlach, &c. + +The contagious typhus of horned cattle is so fully in the epizootic +state in those countries which are washed by the Black Sea, that it was +enough for the veterinarians present at the Congress to manifest a +desire to see cattle afflicted with this disease, for the opportunity so +to do to be immediately afforded them.[D] + +Thus, then, the fact is undeniable, the contagious typhus was raging, in +June, 1865, in Hungary and Russia, as it rages there at all times. + +As for the conveyance of cattle from those countries into England, the +fact is no less certain and assured. It is well known that a convoy of +300 heads of cattle, proceeding from the pasture-grounds of Hungary and +Austria, was transported into Finland by rail, and afterwards shipped at +Revel for England. Thanks to the rapid locomotion by steam, the +migration of these cattle had lasted but ten days--two days for the +transport by land, and eight days for the passage by sea, through the +tortuous line of the Baltic; but this was sufficient length of time for +the incubation to be produced, even supposing the animals to have looked +sound when their transit began. + +Moreover, it is indubitable that the markets of this immeasurable London +have for many years been supplied with horned cattle from every country: +from France, Holland, Belgium, Podolia, Poland, Prussia, Austria, +Hungary, and Russia. + +Thus, the Islington Market (the fact is assured) had received horned +cattle imported from the countries where typhus is known to be +permanent. Were these cattle thus imported affected with the typhus? +This fact likewise is as certain as the other, since two of the foreign +cows thus imported, were the first to fall sick, and to die of this +typhus. + +But if the contagious typhus of horned cattle rages permanently on the +banks of the streams which discharge themselves into the Black Sea, and +if the beasts reared in those countries have long been transported to +England and other countries, how, it will be asked, is it that the +disease has not broken out more frequently, for it has never been seen +in Great Britain, at least, during the former part of the nineteenth +century? + +This question is not devoid of a certain degree of importance, and +deserves to fix our attention for a moment. + +Now the conditions in which the animals were exhibited in 1863 and 1864 +were precisely the same as those of 1865, before the outbreak of the +disease; and yet the contagion has been possible in 1865, whilst it was +not so in 1863. + +We do not presume to explain the mysterious phenomena which govern the +development of epidemics and epizootics; but it seems to us not +altogether impossible to give a rational and satisfactory elucidation of +the facts. + +In general, in _epizootics_, and I might even say in some particular +epidemics--in that of the typhus, for instance--three connected and +inseparable facts form the condition _sine qua non_, of the generation +of the disease. First, a focus for producing the virus; secondly, for +the most part a favourable soil, and a special predisposition amongst +animals to receive and propagate it; thirdly, what is called an epidemic +or epizootic genius--that is to say, a particular state of the +atmospheric elements, or the air, which hitherto has escaped our +analyses, and whose morbific properties vary in their degrees of +intensity. Thus the epizootic genius of 1711, the terrible one of 1750, +and the one which now diffuses its contagious miasma, have differed in +some of their virulent conditions. + +However that may be, it will be sufficient to glance back at the past to +assure ourselves that, in general, epizootics have been coincident with +some violent change of season, such as extreme droughts, or +superabundant rains; that is to say, when the cattle, disturbed in the +physiological conditions of their health, have become favourable to the +incubation of the miasmatic leaven scattered through the air, or else +when these animals were living under irregular conditions, and had to +endure unwonted fatigues and privations, as in the folds of campaigning +armies, for instance. + +These epizootics have appeared to depend not only on the state of the +soil and of the health of the cattle, but also (we repeat it designedly) +on an element no less indispensable to the propagation of the disease--a +special state of the air, which favours the development and preservation +of typhic miasma: for sometimes a sudden change of temperature has +proved sufficient to stop the rampant progress of the contagion, the +other conditions remaining unaltered. + +These relations of cause and effect between the contagious principle, +the predisposition of the animals, and the state of the atmosphere, +evidently are subject to some exceptions; but we must allow that in the +present epizootic they are absolutely and completely applicable. For, in +truth, the years 1864 and 1865 have been distinguished, if not by the +persistency of a high rate of temperature not often witnessed, at least +by an excessive drought during the months which are both hot and rainy; +and this has happened in the various countries of Europe, thereby +producing a falling off in the pasture and fodder both as respects their +quantity and quality. + +As to England, a country usually cold and damp, but renowned for its +spacious green fields and meadows, it has suffered more than any other +country from these unfavourable conditions, and their destructive +influence on the grass and corn; the herds having found a great +reduction of food where formerly they met with abundance. Everybody has +seen, as we have ourselves, large herds of cattle, wandering in +amazement from field to field, and seeking for something to browse on a +parched and arid soil. A supplementary provision of corn, roots, malt, +and the grounds of the beer vat or spirit barrel, no doubt served to +mitigate the sad effects of these privations on the health of cattle; +but in spite of all that could be done, their blood became impoverished, +their strength and vital resistance sank, and (like the animals which we +transferred at will into a soil more favourable to the spread of +parasitic diseases), they afforded last June, as they do now, an unusual +predisposition to suffer and transform the morbific principles of +typhus, which in all probability they would have been proof against at +any other time. We may very fairly infer this much, for we must of +necessity believe that the regular importation of cattle from those +countries which are considered as the permanent focus of typhus, has +from time to time transported the miasmatic germs of this malady into +England, although the virus did not take effect on British cattle at +those periods, for want of one or other of the conditions necessary to +its generation and development. + +We may likewise infer, and a watchful appreciation of the facts +contained in the veterinary medical journals would show that this +opinion is not unfounded, that the special disease which constitutes +this typhus (similar in that respect to epidemic diseases), may develop +itself in one beast by accident, spontaneously, sporadically--that is to +say, without immediate contagion; in a word, _apart from those epizootic +conditions which alone render its propagation possible_. To be brief, we +think that an isolated case of cattle typhus may by chance be detected, +when there is no epizootia prevailing to account for it, just as we +occasionally meet with cases of typhus or cholera among men during +seasons absolutely free from these epidemics. It would not, therefore, +appear to us altogether impossible, that under the influence of very +special conditions, the contagious typhus of the ox might have its birth +in England; and this would favour the theory of those reasoners who +maintain that this typhus met with the first causes, and the origin of +its development, in the stalls and cowsheds of London. But such has not +been the cause of cattle typhus in the epizootia which we see at +present. + +No doubt some animals suffered great privations, but, whatever +alteration their health may have sustained, all this is nothing to be +compared to the sufferings endured by the cattle in the steppes under +the influence of deleterious conditions of the most exceptional +character, which do, indeed, give birth to this typhus, and which we +have already described. + +No, certainly not! _Nothing authorizes us to believe that the typhus now +under our observation was bred and born, at first, within the stalls and +cowsheds of London._ It was most assuredly imported. But it is true, +nevertheless, that this cruel scourge found the horned cattle of England +predisposed to receive it, and it likewise met with atmospheric +conditions favourable to its subsequent diffusion; in a word, it met +with the epizootic genius proper for the generation and propagation of +the typhus miasma. + +It is thus that we may account for and reconcile the two contending +theories, one of which refers the cause of this typhus to foreign +importation, whilst the other insists that it originated in the filthy +and half-ventilated cowsheds of the metropolis. + +But if this typhus could not spring up spontaneously out of the bovine +race of England, it must be confessed that, independently of the general +predisposition due to a great and protracted drought, it found in the +sickening sheds of the metropolitan and country cattle the most +favourable conditions for its incubation and subsequent diffusion. + +It would, indeed, be difficult to conceive of anything more directly +adverse to the hygienic laws of health in cattle than the stalls and +sheds dotted over the densely populated districts of London. Most of +these pent-up cribs are situated in narrow lanes and yards, in filthy +streets and blind alleys; and within these close, hot, and steaming +receptacles the miserable cows, pressed against each other, without +ever moving a limb, waste away and become phthisical in a very short +space of time. We may readily imagine what a prey to the contagion must +be afforded by these animals, already more or less ailing, some of which +are fed in a great measure on malt, so sour and acrid that the very +smell of it is intolerable. The milk from these cows is, moreover, of so +wretched a quality, that in a cowhouse containing 48 of these poor +creatures, at Kensington, I found only one, the milk of which exhibited +the taste and quality fit for a sick child, for whom I ordered a milk +diet. + +It is not, therefore, to be wondered at that the present epizootia, +during this late tropical season[E] especially, should have met with all +the conditions most conducive to its development and propagation. + +When the cattle distemper first broke out, the graziers, not suspecting +its gravity, attempted to treat the animals themselves, but soon +afterwards perceiving the fruitlessness of all their remedial measures, +they felt that the best thing they could do was to turn their sick +beasts to whatever account they could, by driving them to market or to +the slaughter-houses, an expedient which they were the more disposed to +adopt, inasmuch as the diseased cows had ceased to give milk. And then, +the removal of these animals, in various stages of the disorder, became +the most rapid means of disseminating the contagion, which, had it been +concentrated and pent-up at first within its narrow focus, would +otherwise have spread with less fearful havoc.[F] + +In the meanwhile the sick cows being commingled with thousands of heads +of cattle exposed for sale at the different markets, communicated far +and wide the principle of the disease; and as a certain number of these +animals remaining unsold were driven back to the farms, into stalls +until then removed from every cause of contagion, they introduced among +their sound companions the fatal germs of the distemper; and as, again, +this effectual means of propagating the evil was repeated several times +in the same week, the consequence was that, by the end of July--a little +more than a month after the outbreak--the whole of the south of England +was in some sort contaminated. Thence the contagion extended to the +north of the kingdom, and passed into Scotland; so that, at present, the +cattle-typhus has spread its ramifications over a great number of the +counties of Great Britain.[G] + +In the first instance, the contagion spread from animal to animal by +means of an infecting influence in some degree direct, among cattle +sheltered beneath the same roof, or collected in swarms within the same +markets. But very soon the air itself was impregnated and polluted by +the vaporization and diffusion of the typhic miasma; and herds of cattle +which had no contact, either direct or indirect, with infected animals, +were seen to be tainted with the distemper. Whether this contamination +was produced by the passage of attainted cattle along the public roads +(having fields on the right and left), or otherwise, nothing but an +absolute isolation, an utter impossibility of contact, appeared to offer +a perfect immunity against the spread of the evil. + +The miasma, condensed by the fogs and transported in all directions by +the winds, now began to overleap every natural or artificial barrier, +and the favoured herds, ruminating at their ease in the manorial farms +of the wealthy patricians, in their well-kept parks and amid every +luxury, were suddenly smitten with an evil which in their case seemed an +anomaly. In such peaceful homes these innocent creatures were tended by +intelligent and benevolent hands, which understood and felt for their +frail constitutions; food of the best quality was lavishly supplied to +them, and whatever they could wish for lay around them in abundance; +richly reared, they had themselves become so many ornaments within these +scenes of beauty, and all men thought that here, at least, were plots of +rural ground which the genius of epizootia would not invade, and in +which the healthy herds were invulnerable to contagion. + +It was under these circumstances that the fine farms of Earl Granville, +at Golder's Green, skirting the Finchley Road,[H] containing as many as +130 milch cows, were suddenly and fiercely attacked amidst their +seeming immunity, and struck down in great numbers. + +"When I left England a month ago," said the noble lord, "there were +about 130 milch cows in four sheds; in the two largest and best managed +I found only one cow yesterday, September 4th." + +The park of Holly Lodge,[I] which is partly bounded by the main road +along which pass and repass files of cattle going to and coming from the +markets, was visited by the same unsparing scourge. Now certainly, the +noble and beneficent lady of the manor, who secured to her cattle every +attention, and who, confiding in the resources of medical science, +attempted every means to save these stricken creatures doomed to an +inevitable death; she whose enlightened mind, equally open to the claims +of science as to those of misfortune, desired that experiments should be +made which might tend to throw any light on this devastating malady; +she, at any rate, one would think, might have escaped the common lot +without exciting wonder or envy at the privilege which she enjoyed. But +this fell and sweeping epizootia, inexorable in its latitudinarian +march, entered those shady bounds, and decimated those orderly sheds +with the same impartiality as it did that of the poor man, Cutting, +whose whole fortune was stored up in the two milch cows whose death he +had to deplore. + +This epizootia threatens to invade, one by one, all the European States, +like the awful scourge of 1750, to which we have already drawn +attention. For even now Holland and Belgium[J] have been smitten; and +the alarm it has excited has for a time superseded the panic which the +stealthy advance of the cholera to the west had kindled. Some imagine +that it might have been kept out of Great Britain, or have been checked +in its outbreak. But, in spite of all the safest precautions and the +soundest measures of preparation, it would most likely have baffled +human skill, and neither been held aloof nor stifled in its focus. But +how painful it is, to have to write and to think that ignorance, +carelessness, revolting cupidity, and the most wanton violation of the +laws, have all contributed to extend the evil, with the foulest +premeditation and the blindest disregard! + +To feel one's self a stranger in a country, and to be able to rejoice at +one's connexions with it, and at the same time to be obliged to give +publicity to certain truths distasteful to those to whom they are told, +is a most painful task. But, as it would be to swerve from that duty and +loyalty which the national interests as well as those of science impose +upon a writer, not to speak out with impartial justice in a matter of so +vital an importance, we beg permission to consider, without reserve, +this delicate question:--the causes which have contributed to propagate +the complaint. + + +V. + +England, so long spared by that wasting scourge, which had so often +extended its ravages over France and other kingdoms during the last +sixty years, was taken by surprise; and the regulations and laws +necessary to stifle without delay the distemper in its focus--that is to +say, in the metropolis--not being in readiness, the outbreak of the +disease found her helpless and unarmed. + +On the other hand, the organic forms of the English Government and +municipal bodies, the reserve of the Cabinet during the vacation, the +limited power of the Lord Mayor and his civic counsellors, the +subdivision of London into parishes and vestries, as in the good times +of the middle ages, the loose scattering of the shambles and meat +markets through the many streets of the huge town, the right asserted by +each man to be absolutely independent and free, the sanctity of the +Englishman's home, &c., &c., all concurred to let loose and propagate +the contagion, instead of keeping it within bounds. + +Indeed, whilst the competent authorities, with all the energy which +could be expected of them on so grave a matter, were meeting and +discussing the best measures to be taken, and the interesting debates at +the Mansion-house were throwing the first light upon the question, the +insidious malady pursued its destructive progress, diffusing new terror +and alarm. When at length the Privy Council issued their orders, +prescribing the public declaration of sick cattle, and that no affected +beast was to be conveyed either by rail or by ship, whilst all the +necessary means of purification and disinfection were to be employed, +&c., it was unfortunately too late, the dreadful calamity having taken +root and multiplied its stem like the upas-tree. + +What a field for reflection there is in these cases, which originating +with the imperfect state of the laws and institutions, have fostered and +encouraged the disease! But this is a subject which it would not behove +us to discuss, and we prefer to show by the notes which will be found +appended to the end of this work, and which are produced as attesting +documents, that cattle proprietors, by their own confession, too often +sacrifice the interests of the public to their own private advantage.[K] + +Nor have we been able to participate in the thoughts and reflections of +so many sensible and judicious persons, on the impotence and +dilatoriness of the public authorities, and also, let us say, on the +inadequate pecuniary means proposed by a people so lavish of its wealth +when useful and great undertakings are designed, without paying a +natural tribute of regret, to the memory of a Prince who took so deep an +interest in the progress of agriculture, and who, had he still been +living, would have known how to direct with a firm and steady hand, the +right measures to be taken amidst so many intricacies and +embarrassments. + +Sometimes allusion has been made to France in the speeches delivered at +these meetings, presided over by that active magistrate, the Lord Mayor. +In the course of these remarks the speakers have praised and held up to +admiration the advantages of her system of centralization, the decrees +of her sanitary police, and the promptness with which she executes the +measures which the public interests require. That is true. France is +certainly in a state to resist the scourge with very effectual means to +arrest its progress; but if in this matter, as in some others, she have +acquired a superiority, it has only been by an experience dearly +purchased, these epizootics having returned more than once to destroy +her flocks and herds. Politically, the same might be said of her +revolutions, those great moral epidemics. + +An orator, a writer, went so far as to say, in one of his numerous +letters, the one dated the 24th of August: "I regret to say some of our +neighbours laugh at our expense."[L] + +No, your neighbours will not laugh at your misfortunes. They sympathize +at present both in your joys and sorrows, and if I have taken up my pen +on this occasion, it has only been because I could not look with +indifference on your too just anxieties, when I flattered myself that I +might write some useful pages to mitigate and relieve them. + +As most newspaper readers are aware,[M] and as everybody may easily +ascertain, the diseased cattle, in spite of reiterated orders to destroy +them immediately, were, nevertheless, driven to the markets to be sold +for what could be got for them; or when their tainted condition was too +glaring they were at once sent off to the private shambles, the owners +of which, in order to disguise the accusatory proof of the misdemeanor, +hastened to sell the body of the animal. It would be quite impossible to +mention all the violations of the law, which every day continue to fill +the columns of the public journals. One graceless wretch, who deserved +to be hanged for it, if his ignorance do not excuse him, was so infamous +as to introduce a sick cow into a shed not yet attainted, in his +criminal desire of propagating the disease there.[N] + +Thus, then, independently of the causes inherent to the typhus itself, +which served of necessity to diffuse it, other causes proceeding from +the defective state of the law, and the perfidy of individuals, have +contributed to its dissemination. And yet the Government circulars, the +newspapers, and the reports of veterinary doctors have made known that +the slightest omissions and inattentions were serious--that the want of +ventilation and cleanliness in the stables, the overcrowding of the +cattle, and their abiding near their own droppings, or dung-heaps--that +the keeping of dead bodies close to farms, cowsheds, enclosed grounds, +and fields--that the hasty and imperfect burial of cattle--that the +collection and transit of their fragments, bones, horns, and skins--that +the driving on the public roads of any animal either tainted itself, or +having lived among those that were sick--that the clothes of persons and +stable utensils, soiled with putrid liquids--that all these, and similar +causes, were capable of propagating or aggravating the disease. + +But whilst we must loudly condemn the voluntary misdeeds of those who +drove their sick cattle to market, it must likewise be allowed that, to +conform one's self rigidly to the given injunctions, was sometimes +attended with serious embarrassments. How great, indeed, must have been +the perplexity of any grazier who, being the owner, for instance, of +forty head of cattle, and having seen ten of them perish under his eyes, +without knowing where to dispose of them, was threatened with the loss +of the remaining thirty within a few days! How could he calmly and +patiently resign himself to suffer so large a quantity of animal matter +to accumulate and putrefy around him, when, suddenly ruined, and +destitute of every resource, the authorities held back instead of coming +to his assistance. + +The prime cause of all the transgressions committed in despite of the +Privy Council's orders, may therefore be referred in part to the want +of compensation to be granted to the owners of infected cattle. It all +might be almost reduced to a question of money. For let us suppose for a +moment, that inspectors entrusted with adequate powers, had been +authorized, after a close examination, to point out the tainted cattle; +to fix a moderate price on them by way of compensation; to have them +slaughtered, carried away, and immediately buried, would not such a +course have diminished the generation of contagious miasma in a +considerable proportion? + +Moreover, some cattle-breeders and farmers exposed themselves to the +imposition of fines and penalties without any evil designs; for when +they drove their beasts to market they were only in the stage of +incubation, at the preliminary period, when it is really no easy task to +distinguish the distemper. The following fact will exemplify this. + +At each market, in spite of continual warnings, the inspectors pick out +and despatch to the slaughter-houses a certain number of sick cattle, +not only those affected with typhus, but with other disorders. One +cannot help wondering, on seeing the poor, lean, sickly condition of +some of these creatures, how their owners could have been so mad as to +expose them for sale; but in their number there are a few which, +although sick, appear in good health to the common observer. + +About a fortnight ago, during one of our visits to the great +Metropolitan Market, Mr. Tegg, the veterinary inspector, whose +intelligence and earnestness are quite equal to the very difficult +charge with which he is entrusted, ordered to be seized and removed to a +secluded fold near the slaughter-houses, a dozen diseased animals. When +once these cattle had been thus collected in a body, it was easy to +submit them to a still closer examination. Most of these beasts, adult +cows and oxen, were lean, panting, feverish, dispirited, and remained +motionless where they stood. But among them was a cow, with a brisk and +lively look, a quick open eye, which watched us with anxiety, and fled +at our approach every time we passed by her. The turn came for this cow +to be examined. Mr. Tegg, strong and handy--as every good veterinary +doctor should be--seized hold of one of her horns, but he was quickly +shaken off; other persons came up to assist him; the fiery animal was +suddenly seized by both horns, by the nostrils, and the tail; but so +strong and spirited was the animal, that she defended herself with +advantage against all her adversaries, and once more shook herself free. + +It was necessary, however, to master the creature, so they surrounded +her again, pressing her back this time into a corner of the pen, to +overpower her. But lo! the animal takes a sudden spring, and leaps over +the bars. Assuredly this cow, for a beast suspected of the typhus taint, +had given a proof, if not of health, at least of extraordinary vigour; +and her owner, who had seen her condemned with much vexation, now +thought he saw ample reason to reclaim her, and drive her back to the +market for sale. However the cow, on taking such a leap, and under +conditions so unfavourable, came down with all her weight upon her +limbs, fracturing one of her forelegs. + +After this accident, we were able to prosecute the examination we +desired, and Mr. Tegg showed us a row of little glandular swellings on +the ridge of the gums, and livid spots on the vaginal mucous membrane, +which confirmed his diagnosis. The owner of this cow, nevertheless, +still discredited the diseased state of the beast; so to convince him, +she was driven off at once to the slaughter-house to be struck down; +but, unfortunately, three or four others filled the required area, so +that the poor cow was forced to witness the execution of her +fellow-creatures before being killed herself. The look and posture of +this cow, her excited yet terrified glance as she surveyed this scene of +carnage, was one of those pictures which no pencil could draw; and +although we acknowledge that man possesses an incontestable right to +apply to his own use the dead or live matter of animals for his food and +sustenance, we could not help feeling for the poor victim, slipping over +the blood, and thus scenting death before receiving the stroke. + +We are not excessively sensitive; we have seen a hundred horses bleeding +from the incisions made by veterinary pupils, and scores of oxen +slaughtered; we ourselves have practised numerous experiments on +animals; but the affecting sight of that animal witnessing the slaughter +of others, and waiting her turn to die, touched us deeply. We could not +help asking ourselves, how it was that man could dispense with +compassion and good feeling even in that bloody toil, and why he did not +bandage the eyes of the doomed creatures he was going to sacrifice? +These dumb animals that we treat like inert matter are sensitive like +ourselves; they are very conscious of pain; and if it be our privilege +to compute the number of our days, we ought not to forget that they are, +like us, endowed with intelligence, so that when they are thus detained +at the place of execution, all their senses and faculties being +concentrated on their destroyer, they are fully conscious of the cruel +fate which awaits them. + +At last it was the poor beast's turn to be slaughtered, and ten minutes +afterwards we opened her entrails, and had proof that Mr. Tegg's +judgment was exact, for already the stomach and intestines offered to +view indubitable signs of the typhus at its first period. + +The owner of the cow was then convinced and brought to reason, but he +still very fairly asserted the goodness of his motives, about which none +present doubted at all, and applied for compensation to the full value +of the beast, both as butcher's meat and offal, which application was +granted. + +Judge, therefore, by this particular example, how many tainted cattle +there must have been which have propagated this distemper, some with and +some without the knowledge of their owners; and, "_horresco referens!_" +how much of this tainted meat must have been purchased and eaten by the +public, since this cow had all the appearance of health and vigour, and +the real diseased condition might not have been detected at all, but for +the experience and sagacity of Mr. Tegg, the inspector. + + +VI. + +In this consideration of the causes of the contagious typhus in bovine +cattle, we have deemed it essential to invite attention both to those +which are generally recognised and admitted, and to those which, though +they may have been settled in the minds of observant and experienced +men, may yet appear hypothetical to certain readers. + +Besides which, in every scientific work, allowance must be made for the +past and future; and here we have two vital distinctions. If the man +who undertakes this task does not go on, he falls back; and it was to +avoid incurring this reproach that we have passed our old boundaries and +visited new avenues. We are aware that more than one objection might be +urged against the opinions and theories which we have exposed, in order +to account for the outbreak of typhus in England; we might anticipate, +we might reply to these objections; but we would rather recapitulate our +inquiry into the causes, in the tangible form of practical propositions. + +From the general considerations above given, we think we may conclude, + +1st. That the causes which generate the cattle typhus on our globe are +permanent and unceasing, not only on the banks of the great rivers which +empty themselves into the Black Sea, but also in other countries--in +America, in Africa, &c.; wherever, in a word, exist the conditions, not +of race (the race of the animal in this case being but secondary), but +of climate and of the organic elements which are indispensable to the +formation and development of typhic miasma. + +2nd. That the cattle typhus, although it exists not necessarily, but +through the improvidence or want of caution in man, on different parts +of the earth, never appears at all in the temperate and more genial +zones, save under particular and special circumstances, analogous in +some degree with those which generate the human typhus--inclemency of +the seasons, overcrowded dwellings, bad or insufficient food, and want +of cleanliness; and that these particular and special circumstances give +birth to the epizootic genus, rendering the cattle fit and apt to +receive the germs of the contagious virus, and to foster its incubation. + +3rd. That the cattle typhus, thus accidentally developed in the +temperate and genial zones, by means of the vicious hygienic conditions +amidst which horned cattle are accustomed to live, and which serve as +the causes of its propagation, is afterwards transmitted by the contact +of animals living in the same stall or shed, or collected in herds on +the same ground, or transported in the same vehicles, by land or sea. + +4th. That the droppings of animals, their litter, their dead bodies, and +their detritus, or broken-up remains--also the stables, vehicles, and +implements which have served for their use, and all matters or +substances which have touched them or approached them--are generative +elements of the distemper. + +5th. That the typhic miasma, thus reproduced and multiplied in one place +under the influence of all these producing causes, is conveyed by the +winds to great distances, smiting those well guarded cattle which +appeared to be fully protected from the possibility of infection by +their isolation. + +6th. That the want of prompt and stringent measures first to +concentrate, and then to stifle this typhus in its focus; the love of +lucre, the perfidy of some, and the absence of foresight and caution in +others, may be, and have been in the particular cases which we are +dealing with, material causes and agencies of its diffusion. + +Such we consider to be the causes which engender and propagate cattle +typhus, and which will serve as a basis for the preventive measures to +be employed in order to withstand and check its propagation. + +FOOTNOTES: + +[B] We are aware that the transport of cattle is conducted in a +different manner during the prevalence of this epizootia. The account +given by two German veterinary surgeons of the management of the vessels +of the North German Lloyd's, and of the manner in which the animals are +treated, is a proof of this; but before the appearance of the epizootia, +the transport of animals by land and by sea left much to be desired. +This account will be found at the end of this work (NOTE A); and all +documents in support of the facts which have served as the basis of our +dissertation, are also in the Appendix, arranged alphabetically in the +form of notes. + +[C] See Notes B, C, D, E. + +[D] See Note F. + +[E] On the 15th of September, the thermometer stood at 80 deg. Fahrenheit. + +[F] See Notes G, J. + +[G] See Notes K, L. + +[H] See Note M. + +[I] See Note N. + +[J] See Notes O, P. + +[K] See Notes R, S, T. + +[L] See Note V. + +[M] See Note Y. + +[N] See Note Z. + + + + +CHAPTER III. + +_Description of the Contagious Typhus of the Ox; its Symptoms, Course, +Progress, &c._ + + +I have already written the history of the typhus which affects the ox; I +have shown and dwelt upon the signs and characters of typhus diseases +generally, deducing therefrom the denomination and definition of that of +the ox in particular; finally, I have described the causes which +generate and diffuse it abroad. + +Now, I must make known the various phases and alterations to which the +disease is liable, and which, in the language of the medical schools, +are called its symptoms and characteristics; its progress or course; its +prognosis; its _post-mortem_ appearances, &c. &c. + +This examination, like those which have preceded it, will afford new +foundations for medical practice. + + +I. + +_Symptomatic Characteristics._--The typhus of the ox, like all +infectious and contagious diseases, offers to observation four +successive changes: 1st, a _period of Incubation_, during which the +original structure is subject to internal and latent derangements; 2nd, +a _period of Initiation_, during which the first evident signs of the +disease are manifested; 3rd, a _period of Endurance_, during which the +phenomena are fully developed; 4th, a _period of Decline_, or wasting +atony. + +These divisions and classifications, it will readily be conceived, are +rather fanciful, for nature does not adapt herself to our methodical +forms. Still we shall abide by them, because they have their relative +and practical utility, and because they will afford to the practitioner +suggestions more easily understood; and finally, because the organic +changes are different at these various periods, which in their entirety +constitute the typhus of the bovine species. + +The description of those different phases through which the organism of +cattle smitten with the contagion has to pass, has moreover been given +in a masterly manner by the veterinary physicians of the different +European countries, especially by those in which opportunities to +observe it have been most frequent--that is to say, by the Russian, +German, and French veterinary doctors, Jessen, Roell, D'Arboval, Gelle. + +The English physicians of the 18th century, as we have already seen, +were also in no respect inferior to those of our own time. Finally, Mr. +Simonds, who published a very able Report on his return from his +scientific exploration in Galicia, in 1857, and the skilful Professor +Bouley, in his recent communications to the Academie de Medecine, in +Paris, respecting his examination of the present cattle typhus in +England, have described the disease with minute exactness, as we +ourselves have verified on the various sick beasts which we have seen +during the last two months. + +1. _Period of Incubation._--Several careful experiments, which have been +cited in the historical division of this work, and numerous fortuitous +occasions, have authorized us to assign a duration of nine or twelve +days to the period of incubation, according to the general conditions +of the epizootia, the manner in which the contagion is transmitted, and +the former state of health of the affected cattle. + +Thus an epizootia at the outset, either when it has become general, or +when it is at its decline, does not always transmit typhic miasma of the +same virulent intensity, nor does it always provoke in the frame a +labour of incubation which is invariable. The contagion transmitted from +animal to animal living continually in the same stalls or sheds is +followed by an incubation more quick and active than that which results +from a chance contact in the markets, or from a contagion produced at a +distance, by the transmission of the miasmatic effluvium along the +public highways. + +Let us add to these considerations the relative state of each animal's +health, and we shall then perfectly understand that the incubation must +vary both in its continuance and in the characteristics of its +manifestation. In some animals it scarcely betrays the derangements +produced by its morbid operation: they preserve their appetite and their +usual looks. A close and attentive observation would alone be able to +distinguish some slight alterations in their way of living, in the +regularity of their rumination and sleep. But in others, there is no +mistaking a something irregular and unusual in their appearance and +living; the vital state is no longer the same. Thus an animal which used +to be cheerful and familiar becomes silent and solitary; it browses the +grass with less eagerness and avidity; it lies down more frequently and +longer; it lingers by the side of the hedge along the field, or it +wanders about, here and there, with a listless look, and without any +object. Others moan and complain, bellowing at intervals in an unusual +manner, very expressive of languor and pain. + +But apart from seasons of epizootia, the beasts too often exhibit these +imperceptible shades of variety in their looks and actions for the +attention to be struck by them; these changes, therefore, are almost +always unnoticed. + +However, the typhic miasma absorbed at the same time by the respiratory +and digestive mucous membranes serves to modify the qualities of the +blood, and secretly reacts on the nervous system; soon after, the +animal exhibits more decidedly those changes which previously were +hardly to be detected; his want of appetite is more marked, his sadness +more obvious, and his attention fixes itself more slowly and carelessly +on the objects which surround him. When he is in the shed, his usual +food is found in excess of his wants, his thirst is much keener and more +frequent, and a continual dejection and lowness of spirits or a +transitory agitation disturb all his functions. When the farmers or +graziers notice these premonitory signs for the first time they pay but +little attention thereto; but if the contagion has found its way into +their stalls and sheds they are no longer deceived by them, but begin to +apprehend that in a day or two fresh victims will be added to the +number. + +2. _Period of Initiation._--Soon the elaboration of the virulent miasma +in the organic structure changes the quality of the blood and humours, +the functions of assimilation and secretion are modified, the nervous +centres receive vitiated organic elements and are disturbed in their +physiological conditions, and the smitten animal displays that state of +latent uneasiness which he is imperfectly conscious of by a general +look of heaviness and stupor (+Typhos+), which has suggested for this +disease its name of typhus. + +Indeed, the poor animal's eyes are fixed, the hearing becomes obtuse or +indifferent, as may be seen in the sinking of the ears, those organs +which are so sensitive, so contractile, and so vigilant in herbivorous +animals. With the head hanging down and motionless, the neck stretched +out, their forelegs open and spread, their buttocks drawn together and +one of them completely lax, they seem to succumb beneath the weight of +their bodies. In a word, the animal exhibits through its whole bearing a +heavy sadness, a general dejection, which bespeak a great derangement in +the whole structure. From this time, in the animals which are most +seriously affected, the appetite ceases, the rumination becomes +irregular and partial, whilst in some others the appetite and rumination +are maintained in different degrees. + +But the incubation of the morbid elements pursues its course, the +alteration of the blood becomes general, and the circulation is +increased and quickened. After this the fever interposes and stops the +secretions, that of the udders is dried up, the mucous channels cease to +flow, the mucous membrane of the mouth becomes whitish, the little +glands situated on it are more permanent, especially in the +circumference of the gums; the floor of the tongue and the larynx are +inflamed, the mucous membrane of the cow's sexual organs is red and +furrowed with livid streaks, the white of the eye is parched, and the +skin feels alternately hot and cold, as well as the horns and hoofs. + +Some of the sufferers have an external horripilation, transient +shiverings are felt in the front and hind quarters and at the junction +of the limbs with the trunk. Some pregnant cows near their delivery +miscarry. In a word, at this period of irritation, the whole frame is at +war with the typhic elements which besiege it, and which overcome the +preservative power of the vital forces, and from this general +disturbance arises an incandescent fever, which drains and stops all the +secretions at their source. + +These general symptoms are the first signs and warnings of functional +derangements more significant, which may, however, vary according to the +predispositions of each animal, and transfer their evolutions either to +the nervous centres or to the respiratory mucous membrane, or to that of +the digestive channels, in the inflammatory and febrile form of the +contagious typhus. Such at least is what we observe in the typhus of +1865 in England. + +The functional derangements, in truth, subordinate to and depending on +the predispositions exhibited by the cattle, are far from being the same +in all. In some, the nervous derangements predominate; in others, it is +those of the respiratory, and in others, it is those of the digestive +channels. + +As in this period of irritation the nervous centres are more +particularly affected, the animal suffers cerebral and rickety pains, a +constant cephalalgia, which provokes vague anxiety; he is sometimes +cheerful, sometimes wild and furious; he clenches his teeth and yawns, +the muscles of his face spasmodically contract, the spine feels very +sensitive when pressed, a burning and insatiable thirst comes on, the +breathing is hurried, and the intestinal evacuations are suspended. + +In this form the toxaemia appears to concentrate about the nervous +centres--as is observed elsewhere at the outset of certain violent +fevers, in the typhus and typhoid fever of man, for instance--and some +of their number may perish the victims of these nervous disorders, and +even fall as if struck with electricity. They die apparently from the +result of the typhic poison; for at this second period, we do not trace +in the nervous centres those injuries which might account for so sudden +a death. + +When the respiratory apparatus concentrates upon it the febrile +congestion, the breathing becomes painful, accelerated, embarrassed, +sometimes convulsive, and a deep, oppressive cough is heard from time to +time. The animal, under the yoke of this oppressive uneasiness, turns +his head from right to left, scents, and seems to question his flanks, +where the seat of the disorder is; and then, whether the pulmonary +affection is congestive or inflammatory or emphysematous, he may die of +the consequences of obstruction to the pulmonary circulation and from +the alteration of the blood, under the influence of a slow asphyxia, +but only at the third or fourth period. + +Finally, when the typhus localizes more particularly its morbid +phenomena on the digestive channels, we discern local alterations on the +floor of the tongue and the buccal mucous membrane, spots of livid red, +leaving behind them ulcerations of greater or less extent and depth on +different parts of the intestinal canal. In this form, which follows +more regularly all the periods, constipation is obstinate at the outset, +evacuation of the bowels takes place with difficulty, the faeces are hard +and the urine scanty, the belly is inflated and sensitive. + +Sometimes at this period of initiation, one of these three symptomatic +forms--the nervous, the pulmonary, and the digestive--may predominate +exclusively, so far as to mask the disease as a whole, and to constitute +it a special malady. But in that case, it is only the exaggeration of +the functional derangements which in their total constitute the typhus: +for when the distemper pursues its course, these three principal centres +of life are always affected in different degrees. Thus, not one of the +cattle smitten with the typhus goes through all the phases of the +disease, without suffering at a given moment in its nervous, +respiratory, and digestive functions. + +In this respect, the typhus of the ox presents an apparent analogy with +the typhoid fever in man, although it is different. Consequently, the +name of _typhus fever_ given by some veterinary surgeons, is not +altogether inapplicable to it. + +3. _Period of Duration._--At this stage of the disease, which may be +said to extend from the fourth to the seventh day, the nervous +derangements are confined to symptoms of uneasiness and sensibility +along the dorsal spine; for those cases which exhibited more violent +derangement in the nervous functions have proved fatal. In this period +of the disease the breathing is more embarrassed, particularly when the +pulmonary form of the disease prevails. The pulse, which is hard and +frequent, indicates from forty to sixty pulsations; the beatings of the +heart are more violent and audible; the mucous membranes, dry at the +outbreak, recover their secretions, but these latter are endowed with +irritating properties. Thus the eyelids, swollen and tumefied at the +edges beneath the lashes, drip with a corrosive liquid, which soon marks +its furrow along the chanfrin; the bronchiae, the trachea, the nostrils, +the salivary glands, exude a serosity which runs out of the nasal and +buccal orifices. The exanthematic eruption having discharged itself +through the digestive channels, constipation is followed by diarrhoea, +rumination is completely stopped, the beast declines all solid +nutriment, and pants for drinks,--for those especially which have a +slight taste of acidity in them. + +The derangements at this period pursue a rapid course--the breathing +becomes more and more difficult, the skin is hot and dry, the hairs +stiffen more and more, gases are developed in the cellular tissues +beneath the skin, along the dorsal vertebrae, at the abdominal folds of +the posterior limbs and under the abdomen, in the form of flat, uneven, +crepitant tumours, which crackle when pressed with the hand; the +diarrhoea becomes more liquefied and irritant, for then it is no +longer a flow of droppings covered with mucus which is expelled, but +secretions already putrid, sometimes reddish in colour, and attended +with foetid gases, which induce tenesmus in the rectum, and force up +the tail. The animal grows perceptibly lean, his dejection is extreme, +and cows which are with calf miscarry. + +At night, the animal seems to have an increase of fever, sometimes of a +remittent type, after which he becomes drowsy and lies down to rest +himself or to sleep, if he can; but the difficulty of breathing, the +abdominal pains, soon force him to rise again, which he cannot do +without an effort. + +4. _Period of Decline and Sinking._--This stage is observed to extend +from the eighth day to the twelfth or the fourteenth. The morbid +functions pursue their course, for the disease has its regular phases +and a successive variation of phenomena. The secretions, which a few +days before were fluid and irritating, have undergone a change; they +have become thick and purulent, they flow more slowly from the ocular +mucous membranes, and also from the nasal and buccal, which are red and +inflamed, and they already emit a foetid smell. The dull tarnished +eyes become hollowed, purulent mucus lodges within their orbits, the +bronchiae are stopped up, the breathing grows louder and more panting, +the animal instinctively stretches his neck to ease it; the wasting of +the flesh exposes the bones of the sacrum and coccyx, laying bare the +vertebrae and the ribs; the emphysematous tumours are more extensive and +crackling; the skin, less heated, wrinkles up and splits about the bony +protuberances; the udders are crusty and excoriated; detached boils, +hard and rounded at first, then soft and purulent, begin to show +themselves on the trunk and the upper parts of the limbs. The +diarrhoea, still frequent, becomes bloody and intolerably offensive. + +At this final period the organic structure yields to the effects of a +general alteration of the liquids and solids. The vital force has lost +the power of reaction; a mass of blood, decomposed by the double +influence of a virulent toxaemia and the obstructions of respiration, +conveys to all the organs a principle of dissolution; the nervous system +is in a manner paralysed, as is shown in the animal's insensibility. + +The secretions stop up the various channels and cavities; they lodge +within them; they undergo a putrid decomposition, and pass out with +difficulty in the form of a purulent and bloody flux, in the highest +degree infectious. Very soon the sick animal has ceased really to live; +it struggles and labours with its agony; if the lungs are clogged with +gas or fluid they rattle hurriedly and often; the animal cannot hold its +head up even when lying down, and when standing moves it to and fro as +if affected with the natural shaking of old age, and as if seeking to +ward off some indescribable evil, the occurrence of which it was +awaiting. + +The animal's body is a prey given up beforehand to the laws of organic +decomposition: the internal mucous membrane of the cheeks and lips peels +off in strips when rubbed; the sores on the skin have a livid and +gangrenous look; the eggs which the flies deposit on the edge of the +eyelids and at the nasal orifices, or on the excoriations of the skin, +quickly pass into the state of larvae. The air they expire is cold and +infectious; the native caloric, extinguished in every focus +successively, disappears; the vaginal mucous membrane is tumefied, the +anal opening gapes, and from it flows a bloody and decomposed liquid +which the rectum can no longer expel. The mouth, half open and coated +with a thick glutinous foam, vainly tries to inhale long draughts of air +which can no longer reach the lungs. Finally, if the animal is lying +down, he expires in slow agony, his head borne down by its own weight; +or, if standing, he sinks and falls down, his death having anticipated +the fall. + +Such are the symptoms--the subjective signs which enable us to detect +the contagious typhus of the ox. But all animals do not exhibit these +disorders of the vital functions with the same regularity and excess. +Some of these we have seen, from first to last, sustain the internal +effects of the morbid process--in some sort passively--without revealing +any deep derangements in the nervous, respiratory, and digestive +functions. The poisonous virus had smitten them; they suffered in their +general structure; they looked stupefied; they lost, at a given moment, +their appetite and rumination; they had fever; their breathing had +become short and frequent; they had diarrhoea; they gradually lost +flesh, and the excreta passed through certain changes and +transformations. In a word, the animal had manifestly the bovine typhus; +but, thanks to a relative immunity, to a special organization, which +renders some of these beasts capable of resisting the contagion for a +long period, and sometimes altogether[O]--thanks to that variety which +we observe in different constitutions (for small-pox and typhus in man, +and the true typhoid fever in animals, do not operate with the same +violence on all alike)--thanks to this privileged organization,--we have +seen some oxen pass through every stage of the disease without +exhibiting this terrible train of morbid phenomena. + +In these cases--for even this mild form of the distemper at last +produces death--the injuries fix themselves more exclusively on the +digestive channels, and we witness, in dissection, ulcerations in some, +in others mere spots of a livid red, more or less extensive. + +Finally, although the typhus be one of the gravest maladies which +destroy and decimate cattle, all sick animals are not mortally affected +thereby. In the present epizootia, five per cent., as nearly as can be +ascertained, recover; and when that happens, signs of a favourable omen +are observable during the course of the attack. In these favourable +instances, indeed, the symptoms, even though they exhibit a certain +gravity, pursue a regular course; fever does not become remittent; the +faecal discharge is copious and easy, with less foetor; the animal +loses flesh slowly and progressively; the tumours are cutaneous, +inflammatory; their character is good, depurative, and rather purulent +than gaseous and crackling. The droppings do not show that high degree +of pestilential decomposition described above; the animal in his drink +welcomes and digests a mixture of bran and flour; the secretions of +purulent mucus and the faecal discharges dry up and stop in the early +part of the period of decline; the epidermis of the openings through +which they passed out peels off in thin scales, and afterwards in scurfs +or husks--in a word, the economy does not experience those acute +disturbances which strike one of the tripods of life--that is to say, +either the nervous centres, the lungs, or the digestive organs. + +Now, in these curable cases, in which the cure is most generally due to +nature's own efforts, but which a systematic treatment might render far +more frequent, the convalescence is long, and requires great attention +and a well-regulated diet, in which the food is carefully measured and +divided. Here there must be a rigid superintendence. A laxity in the +watchfulness, or too much reliance on the reviving health, have produced +sudden relapses, and been fatal to many sick cattle, which had been +looked upon as thoroughly cured. For it may well be conceived that +convalescent animals, after sustaining such violent derangements in +their health, and having been brought down to the lowest degree of +prostration and marasmus--to a reconstitution, we may call it, of the +solids and liquids--have a devouring hunger. If, therefore, the keeper +who looks after them unhappily forgets that the principal lesions or +sores are seated in the stomach and intestines, and if he gives them too +much solid nutriment, he impedes the cure, irritates the ulcerations not +yet thoroughly covered over, and soon adds another victim to those which +had already died. + +This convalescence lasts from fifteen to twenty days, and the animal +only recovers its health at last by slow degrees. Still the careful +keeper need not be afraid of a relapse when he is patient and watchful. + +Such, then, is the contagious typhus of the ox. Type of the unreturnable +infectious diseases, its virulent miasms undergo within the structure a +series of transformations: they produce in the frame a general disorder +fully capable of annihilating the predisposition or aptitude of the +animal to receive the taint. A disease essentially specific, it affects +the principal centres of life; it kills its victim both by its deadly +virus and by the local derangements to which it gives rise; for how is +it possible to preserve life when the whole nervous system, that +promoter and regulator of all the functions, is upset?--when the lungs +which revivify the blood, when the digestive organs which are the very +sources of alimentation, are smitten with stagnation?--when, in fine, +not only these vital centres have ceased to operate, but when each by +itself is the cause of torturing pains and exhaustion? + +The typhus, moreover, is observed in all animals of the bovine species, +whatever may be their race, their age, or their sex. The recovered +animals may live with impunity amidst diseased herds of cattle, thanks +to its non-relapsive nature. Jessen has even witnessed cows which, after +their own cure, communicated a sort of immunity to their offspring. For +the same reason it is that epizootias are less fatal in those countries +where they often occur, the constitutions of those animals which are +engendered amongst such habituated herds, preserving a prophylaxy +inherent to the blood which has been transmitted to them. + +Besides, what a pregnant subject is this for the physician, and what +more meritorious task can he set himself than the treatment of such a +distemper, which reason assures him must eventually lead to the cure and +eradication of the same complaint in the human species? + +From a cause which as yet has been indistinguishable and imponderable, +what important, what marvellous results loom in the future! The air +seems to us pure and wholesome, yet it conceals a typhic miasma of the +most deadly kind; it carries this pernicious principle into the richest +meadows, where we see feeding flocks and herds which to us seem +exuberant with health. Then this miasma is inhaled and absorbed, and it +meets in the frame the special and indispensable organic element which +is needed for its multiplication; there it undergoes certain latent +transformations, and a fermentation, a germination, which we call +_incubation_, in order to explain a process which we cannot understand. +Then fever is kindled, all the functions are disturbed, and the sick +animal is struck down, leaving us wondering, ignorant, and powerless +spectators in the presence of phenomena which, nevertheless, are the +eternal work of nature and have endured through all time.--But if in +the invisible typhic atom nature gives us death, it also gives us life +in the zoosperma. + + +II. + +_Lesions found in the Bodies of Oxen after Death._ + +The description which we have given of the disorders produced in the +different functions by the operation of the typhus, may easily suggest +what must be the lesions exhibited by the organs of the body. + +Death, we have said already, may overtake the disease at any of its +periods, and thus show every aspect and every degree of the organic +lesions. Such an animal being struck down at the period of initiation, +will not, of course, present the changes and varieties of the period of +decline, and _vice versa_. + +In general, the state of the dead bodies is that of the most decided +marasmus; the remains are intensely repulsive, as well by the stench +they emit as by the sight they afford; and, in summer especially, +decomposition sets in with great rapidity. Consequently, the utmost care +is required in conveying them from place to place; and this attention +is the more essential, because in the transit, the cavities being +deprived of their contractile power, let flow the pestilential liquids +which they contain, thereby infecting the carriages and public roads. +The urgent necessity there is to inhume at once these dead bodies, the +most active agents in diffusing the contagion, is equally the drift of +this observation. + +The deceased animal, as a subject of anatomy, enables us to certify the +seat of the emphysematous tumours, and to see that they are really due +to the air which insinuates itself into the cellular tissue, and which, +receding from the pressure of the fingers between the cells, produced +the crackling sound we noticed above. This penetration of the air is, +moreover, a far more general effect than was supposed. + +It is ascertained, likewise, from the examination of these subjects, +that the round, fluctuating, and smaller tumours, are indeed purulent +gatherings, which occasionally find a passage into the layers and +interstices of the muscles. + +The muscular flesh is usually flabby, bloodless, unsightly, of a very +nauseous smell; and it would be difficult to imagine that the most +avaricious trickster would dare to offer even the most presentable parts +of it for sale and consumption. But when the expedients and artifices +known to the butcher's trade are had resort to, when, regardless of the +public health, the unprincipled dealer selects the most fleshy parts, +when he dresses and adorns them by colouring them over with the blood of +a healthy beast, the unwary eye of the purchaser may be deceived. +Observe, that we are now speaking of cattle that have died in the last +stage of this marasmus, so that we might suppose, even if the many +summonses before the magistrates, and the too moderate fines which have +been imposed on the guilty parties, had not shed the broadest light upon +the fact, that _a large number of sick cattle which had been slaughtered +at different stages of this frightful disease, have been dressed and +adorned, exposed for sale, sold, and eaten by a very large portion of +the inhabitants of London and of the country likewise_. + +_Digestive Channels._--The mucous membrane of the buccal cavity is, for +the most part, of a livid whiteness; ecchymosed stains, and sometimes +ulcerations, differing in their form and number, are visible on the +floor of the tongue. Mr. Simonds has had an anatomical model +constructed, which presents a perfect type of these ulcerations, some of +which are of a scarlet hue, with perpendicular edges. The _stomachs_ +exhibit a variety of ulcerations. + +The _paunch_, or first stomach, always contains a large quantity of food +intended for rumination; sometimes these aliments are dry, and lie +sticking to its sides; at other times they are diluted with water which +had not yet been absorbed after drinking. The inner membrane of this +first reservoir may show flat spots, with livid injections of different +sizes. + +The _honeycomb_, or second stomach, generally exhibits the same injuries +as the paunch. + +The _manyplies_, or third stomach, contains between its laminae hard, +pulverulent, and dry alimentary substances, which are seen sticking to +the different leaves. On removing these substances, some ecchymosed +spots are laid bare, the epithelium of which easily peels off; +sometimes ulcerations, and even perforations, are visible. + +The _reed_, or fourth stomach, whose sides are thicker, more fleshy, and +more vascular, exhibits within its folds various kinds of lesions or +sores: they consist of large flat stains of a darkish red, more or less +soft, and sometimes ulcerations red on their deep surface, with clean +edges. + +As for the intestines, properly so called, the _duodenum_ shows the same +injuries, but most generally large ecchymosed spots. + +The _small intestine_ appears on the outside, even when it preserves its +place in the abdomen, of a reddish colour, lined with vessels distended +with blood, the signs of a general congestion of its membranes. The +examination of the mucous membrane, after it has been cut open +lengthways, shows, indeed, that this portion of the digestive tube is +the principal seat of the distemper; for, independently of this general +injection, you perceive ulcerations which have succeeded to detached +pustules or lengthy flat spots, the result of a cluster of several of +Peyer's glands, brought together by the plastic influence of +inflammation. These flat spots, or wafers, very similar to those we +observe in the typhoid fever of man, are inflamed and ulcerated in +different degrees. + +The mucous membrane of the _large intestine_ exhibits lesions depending +on the period of the disease. About the third period, the injection is +sometimes general, especially near the rectum; but in the fourth and +last period we often meet with ulcerations which are smaller in the +upper part, larger and deeper about the lower or rectal part. The +membrane of the sexual parts of the cow is strongly injected, and of a +dull red colour. + +As we have seen, the different organs of the digestive apparatus may, in +this typhus, offer to view extensive alterations perfectly consistent +with the gravity of the symptoms or the functional derangements. In two +cases in which disorders of the respiration had prevailed, and which had +been sacrificed on the eighth or tenth day of the disease, we only +observed partial injections of a very limited character, either on the +gastric membranes or on that of the intestine, and which might have +been detected in the case of common intestinal inflammation. Therefore, +in these two cases, the characteristic lesions of the typhus, if they +must be localized in the intestine, were, so to speak, absolutely +wanting. It was, we will not say exactly the same, on four other +animals, three oxen and one cow; but if, in two of them, the fourth +stomach was inflamed, if in the third the small intestine was congested, +and if, lastly, in the cow the large intestine showed ulcerations, we +could not in these lesions distinguish those of typhoid fever. + +These facts struck us with great surprise, for we were far from +suspecting them. We hoped, on opening the intestine of these animals, +which had certainly all died of the typhus, to meet assuredly in a +determined spot some well-known lesion declared beforehand. To our great +astonishment, such has not always been the case. So that our theories, +conclusive as they seemed on the identity of the ox typhus and the +typhoid fever in man, and which more than anyone else we wished to see +confirmed, must submit to observation. + +In fine, in this epizootia the intestinal lesions or sores present +different appearances. Developed to the utmost in some cases, so much so +as to exhibit ulcerations at the root of the tongue as well as in the +intestines, and to be in a manner the excess of the injuries which are +seen in typhoid fever, they are in other cases scarcely perceptible, and +sometimes entirely absent, when the animal is struck down in the third +or fourth period, that is to say, when the exanthematic or pustular +state has had time to develope itself on the digestive channels. One of +these animals seized by Mr. Tegg at the Camden Town market, was in such +a state of exhaustion that he could not be driven to the +slaughter-house, only two hundred yards distant; they were forced to +fell him on the spot midway, in order to have him conveyed to the place +of dissection. We only detected partial injections on the digestive tube +of this beast. The pulmonary emphysema which had caused this animal's +death was developed in the highest degree.--He was opened at the request +of M. Bouley, of Alfort. + +_Apparatus of Respiration._--Here, again, the typhus shows us injuries +which differ from those of typhoid fever; for if the breathing is always +more or less obstructed at the outbreak of this fever, no serious +organic change in the lungs is the consequence thereof. In the ox +typhus, on the contrary, when the pulmonary form prevails, the +derangements of the respiratory organs are remarkable. Thus, the mucous +membrane of the nostrils, from which flows a purulent and fetid mucus, +is sometimes ulcerated and excoriated. The larynx and the trachea or +windpipe, choked up with frothy mucus, show the same alterations, though +less frequently. The lungs, which are rather congested than inflamed, +are emphysematous, the air having entered and distended the cellular +tissue which unites the lobes together. + +In some cases, the lungs are so gorged with air that their lobes +constitute but a single heap, rendering them irrecognisable, so greatly +do their volume, their specific gravity, and their spongy aeriform +aspect differ from the natural state. + +_Apparatus of Circulation._--The inner sides of the heart show +ecchymosed spots, and the same is the case with the larger vessels. The +blood, diminished in its quantity and altered in its quality, is +blackish and more fluid; but in most cases it coagulates instantaneously +and in a mass, without separating into its solid and liquid parts. + +_Nervous System._--Having observed and dissected the dead bodies at the +slaughter-houses of the markets, we were not able to examine either the +brain or the spinal marrow. Besides, let us remark in this place, that +the mode of felling cattle in England would have rendered impossible +such an examination. For the animals are struck with a club, which kills +them both by cerebral concussion and by the direct alteration of the +brain; the instrument having a sharp end which perforates the skull and +injures the cerebral lobes. Nor is this all; the moment the animal is +struck down, a flexible rod is inserted into the hole made in the skull, +and driven as far as the spinal canal, so as to tear to pieces the +protuberance and the bulb, that is to say, the vital knot. This manner +of killing cattle seems to us, however, preferable to the one adopted +in France, where the animal does not sink till he has been struck +repeatedly with the club. + +But be that as it may, those authors who have examined the nervous +centres of horned cattle which had perished victims of the typhus, have +usually found the meninges, or membranes that envelope the brain, +injected, whilst the brain itself was slightly dotted over with blood. + +These anatomical lesions of the nervous centres being insufficient of +themselves to explain the death at the second period, we have +endeavoured to give the explanation of it in treating of the symptoms. + +The other organs, the spleen, the liver, the kidneys, present +alterations of a secondary interest only. + + +III. + + _Diagnosis--Prognosis--Use of the Flesh of Animals which have + Died of the Typhus--Danger of direct Absorption._ + +The typhus of the ox has such distinct and strongly marked +characteristics that it is not easily mistaken. However, to conform +ourselves to received custom, I will say some words about the principal +symptoms of some distempers affecting the ox, between which and typhus +unprofessional persons might be embarrassed, and hesitate to distinguish +them. We will transfer, however, those particulars pertaining to the +diagnosis to the part written for the special use of agriculturists, +farmers, and graziers, in order that they may readily find whatever it +may be necessary for them to know when they chance to have any sick and +tainted cattle to treat and cure. + +We have likewise a few words to say on the subject of the prognosis of +the disease, as regards its propagation and its time of lasting. +Finally, we will unfold a question of very real importance in +hygiene--we mean the use and consumption of the flesh of animals as +food, and the danger which may accrue to man and other animals from +contact with their dead bodies, or fragments of the same. + +The diseases of the ox, which we are accustomed to consider as +distinguished from typhus, are the contagious peripneumonia, the +apthous fever, and the "charbonneux" typhus; but, as we have just said, +we will mention by-and-by their chief characteristics. + +Everyone is anxious, and natural indeed is that anxiety, to know what +this epizootia will become--what will be its course; how long it will +last; whether it will extend its ravages over the whole extent of the +three kingdoms; and if, in fine, it will invade all Europe. + +To answer in a precise manner these questions would be a difficult task; +for who amongst us can assign at present any definite course to the +atmospheric variations? and yet they have a genuine influence on the +progress of the epizootia. On the other hand, the measures which have +been taken hitherto to confine the contagion to its different foci, have +unhappily proved almost ineffectual, but it may be hoped that, assisted +by experience, we shall be able to resist the evil more effectually, and +check its propagation. + +If the atmospheric conditions and the preventive measures could not +modify the spread of the distemper, we should have reason to dread a +still greater extension of the contagion; for the virulent character of +the epizootia appears to be of an exceptional intensity, and we may +perhaps compare it with the famous epizootia, of the middle of the +eighteenth century, which for ten years afflicted all Europe with its +ravages, striking down six millions of horned cattle. + +Let the reader cast an eye over the extracts borrowed from the +physicians of the principal faculties who have described this typhus, +and which we have reproduced in the first part of this book relating to +its history, and he will then be convinced that the disease is +absolutely the same as that which then raged so fiercely. And if that is +the case, we must anticipate that it will extend its ravages whilst +prolonging its duration. Already it has spread to Holland and Belgium; +Hungary and other provinces in the south-east of Germany--a fact much +less surprising--are likewise smitten with it; and now we hear the news +that France, though so vigilantly on her guard, has seen her frontiers +passed over. In spite of the _cordon sanitaire_ which she had prudently +established everywhere, some horned cattle have been seized with the +typhus at the town of Raubaix, in the north. + +Without setting ourselves up as pessimists, let us declare that we must +expect that the contagion will continue to spread. Let us make up our +minds to this, in order to take the necessary sanitary measures, and set +ourselves seriously to work by trying the preventive treatment. But, +alas! between the Government, the municipal corporations, the +agricultural societies, the cattle proprietors, and, with regret we add, +the veterinary surgeons, there has been sadly wanting, up to the present +time, that mutual understanding; that prompt and decisive action, and +those pecuniary advances which are so necessary to encounter and contend +with this great calamity. + +As for estimating with any approach to accuracy the sacrifice of +property; the pecuniary loss, which this fatal epizootic may occasion +the country, the want of exact statistics as to the number of cattle +which have already been struck down will not permit us to do it. But we +may, perhaps, already set it down approximately from 50,000 to 60,000 +head of cattle for England and Scotland, until we have obtained more +precise statistical information on this significant point of inquiry. + +That would represent, however, a very considerable capital; for if we +compute the loss of each animal at the average sum of 15_l._ only, the +sacrifice already incurred would not be less than from 750,000_l._ to +900,000_l._ This sacrifice in money might possibly have proved the be +all and the end all; and at this point we might, perhaps, have arrested +the contagion, had we all been able to act advisedly and harmoniously +together, in the name and for the interest of the public, from the first +appearance of the disease. But this calculation of, let us say, +900,000_l._, is made on the supposition that each cattle owner had been +willing to abide by his own loss; whereas, unfortunately, many of them +have striven to shift it on others, and large numbers of the sick and +tainted beasts having been sold and consumed, a proportionate sum thus +recovered by those avaricious men must be of course _deducted_ from this +estimate. Deducted, indeed! Considering the consequences on the public +health, is it not rather an aggravation than a mitigation of the loss? + +These last assertions naturally lead us to inquire whether we are not +justified in saying that the flesh of sick and tainted cattle, thus +circulated and consumed, has not had its baleful effects on the public +health. + +The butchers who sold the flesh of these sick and tainted cattle have no +doubt been careful to abstain from using it in their own families; and +the first time they speculated on the health of their fellow-citizens, +well knowing what they did, their conscience probably reproached them +with the misdemeanour. But afterwards, when no bad consequences to their +customers had been seen, their own impunity, joined to this apparent +harmlessness to their neighbours, rendered them bolder, and it became a +daily habit with them to sell this peccant offal, which poisons even the +earth by its contact. + +Moreover, the graziers themselves were in league with the butchers, and +took care to slaughter the affected animals before the wasting of their +flesh by the progress of the distemper had bereft them of their greatest +value. Their private interest prompting them thus to dispose of the +sick animals as fast as they could, the majority of the tainted beasts +were sold and eaten in the second stage or period of the typhus. + +Now, if the flesh of these diseased animals had been eaten raw, +accidents most terrible and appalling would certainly have been the +consequence, although dogs may have fed upon it without injury. But the +cooking of animal flesh at 100 degrees of heat has the property of +destroying for a time the septic germs, as the famous debates now being +held by the experimentalists who are studying the subject of spontaneous +generation tend to show. This poisonous meat, therefore, may at first +have been digested without producing immediate ill effects. + +Our medical practice, however, authorizes us to declare that, after +making every allowance for the influences of this extraordinarily hot +summer, digestive and nervous complaints of the acutest description, and +without any special cause to account for them, have been very numerous +indeed during the last two months, and beyond all proportion greater +than they usually are in London. And we cannot but feel that, if the +cholera should reach the shores of England at this critical conjuncture, +it will find organisms most ready to receive its virus. Then, indeed, if +the typhic miasma come to mix and blend with the choleraic miasma, all +living beings will have to contend with the most deleterious causes of +alterations in their health, and we may (God send it be otherwise!) +witness one of those measureless calamities which, known in former ages +as the _Black Pestilence_, decimated cattle and men indiscriminately, +and which, when we read the sorrowful accounts of it in history, make +the flesh creep with affright. + +We sincerely hope that such misfortunes may be spared us. But ought we +to abstain entirely and absolutely from consuming the flesh of cattle +smitten with typhus? It is a delicate question, but still we shall +answer it, making due allowance for every interest concerned. + +We conceive that all animals which are smitten with the early effects of +the disorder, which begin to operate at the opening of its second +period, that is to say, when the first symptoms are declared, such as +stupor, loss of appetite and shiverings, may be handed over to the +butchers. But this must only be done on the _positive understanding and +condition_ that every animal, sick or not sick, in times of epizootia, +shall pass, either in the farm, the market, or the stable, under the +examination of a competent veterinary inspector, who shall mark the +beast when fit to be sold for consumption. With this precaution, which +at present is put in practice in Belgium, every interest is cared for +and guarded--those of the public health as well as those of the cattle +owners. + +But there is another question of some importance which deserves to fix +our attention for a moment. People sometimes inquire whether the +ox-typhus can be communicated to other animals, and even to man, either +by contact, by direct absorption, or by inhaling the miasma floating in +the atmosphere. + +Experiments of great interest might be made on this subject; but we can +already assert, on the evidence of facts publicly known, that the direct +absorption of putrid matter and purulent secretions, and likewise the +mere contact with tainted flesh, when the epidermis or scarf-skin is +cracked or peeled off, or when the least open sore exists, may give +access to the disease, and produce death, both in man and other animals. +In these cases, the absorbed virus operates, not as a specific agent, +giving birth to typhus, but as a provocative septic agent, endowed with +infectious properties, which infuse into the economy a germ of virulent +and mortal disease. So long as a sound and intact outer skin stands as a +safeguard between us and absorption, we may fearlessly touch and handle +the tainted flesh of these animals. But the slightest sore or abrasion +is an open door to let in death. A young veterinary surgeon, who had a +slight wound in one of his arms, was carried off within forty-eight +hours, as was proved at a coroner's inquest, after he had dissected an +ox which had died of the typhus.[P] + +We see by this fatal example that we must be particularly careful not to +touch an ox tainted with typhus when we carry about us any open sore, +unless we take the utmost precaution in order to guard against all +direct contact or absorption. Man, as we have said and shown, breathes +with comparative impunity an atmosphere laden with the infectious miasma +of this typhus. But that which to-day is true may not be true +to-morrow; let us, therefore, be also on our guard against the too +continuous absorption of an atmosphere impregnated with these +deleterious principles. + +As for herbivorous animals in general, a similar organization must, in +their cases, predispose them to receive the contagion. Whenever we visit +the markets, we cannot help fearing to see the ox typhus communicated to +the sheep and pigs which are stationed around them. It is an +unquestionable fact that, in certain epizootias, all animals without +distinction have been smitten and struck down, and the herbivorous +animals more rapidly than any other. The habit of collecting such vast +numbers of cattle in the same market, and on the same day, though +convenient for business, appears to us injudicious, especially during +the prevalence of this scourge. + +This part of our treatise was in the printer's hands when Mr. Simonds +wrote a letter to the Privy Council which justifies all our +apprehensions. The typhus of the ox has been communicated to a number of +sheep, and we must all expect to see this cruel disease assume much +larger proportions than heretofore, since it has now obtained a second +focus for its maintenance and dissemination. + + "Veterinary Department, 23, New-street, Spring-gardens, + Sept. 25th. + + "SIR,--I beg to report that, acting on the + instructions received from you to investigate without loss + of time the statement received at your office relative to an + outbreak of the cattle plague in a remote part of the county + of Norfolk, supposed to have arisen from cattle having been + in contact with some diseased sheep, recently brought to the + premises, I have visited the district in question, and + inquired into all the circumstances of the case. + + "It appears that as far back as the 17th of August Mr. C. + Temple, farmer and merchant, of Blakeney, received on his + farm 120 lambs which he had instructed a dealer to procure + for him for feeding purposes. + + "The lambs were bought at Thetford-fair on the preceding + day, and were immediately sent by rail to Fakenham, from + which place they were driven to Blakeney, a distance of + about ten miles. On their arrival they appeared to be + fatigued to a greater extent than ordinary, which was, + however, attributed to the heat of the weather and the + exertion the animals had undergone. + + "In addition to this, the shepherd observed that several of + them seemed unwell, and he remarked to his master that they + did not appear to be a 'very healthy lot,' and that he + thought it would be better to return them to the dealer. + Within a day or two of this time the symptoms of illness + were more marked in all the original cases, and many more of + the animals had been attacked. On the 24th two of the worst + cases were removed from the field to the farm premises, and + were placed in a shed for treatment, in which afterwards a + cow was put. On the 25th two of the lambs died, and in + consequence of this, and of the large number which were now + affected, the whole were brought, on the morning of the + 27th, into the same yard where the shed previously alluded + to was situated. There is also another shed, separated from + this yard only by some old furze faggots, into which the + cows were driven night and morning for being milked. The + lambs remained in the yard till the morning of the 28th, + when having had some medicine administered to them, they + were returned to the fold and never came again near the + cows. + + "While in the yard three died, two on the 27th, and one on + the 28th, and on the following day two others died in the + field. From this time the disease went on, so that by + Friday last, the 22nd of September, the day of my visit, + forty-six had either died or been killed, and twenty-seven + were in a very precarious condition. + + "On the 7th of September, ten days after the last exposure + to the sheep, a cow gave evidence of being affected with the + cattle plague, this animal being the one which had been put + into the shed occupied by the diseased sheep on the 24th of + August. A second cow was attacked on the 11th of September, + and a third shortly afterwards, which was followed by + others; so that by the 16th all the cows, six in number, a + heifer, and a calf, were all dead. + + "My examination of the lambs showed that they were + unmistakably the subjects of the plague. The symptoms agreed + in almost every particular with those observed in cattle + affected with the malady, and the _post-mortem_ appearances + were also identical. + + "With a view to ascertain the true nature of the changes + produced in the system prior to death, I had four of the + lambs killed, and from these I took some diseased parts and + forwarded them to the Royal Veterinary College without note + or comment. These parts were examined by my colleague, Mr. + Varnell, who at once recognised the special changes of + structure which are caused by the cattle plague. + + "The whole facts of the case leave not the least doubt of + sheep being liable to the disease termed the cattle plague, + and that when affected they can easily communicate the + malady to the ox tribe; and moreover, that when so conveyed + it proves equally as destructive as when propagated from ox + to ox in the ordinary manner. + + "The case is also more important from having occurred in a + place no less than fourteen miles distant from any other + where the cattle plague exists, thus placing beyond a doubt + the fact of the malady being introduced among the cattle by + the sheep alone. + + "I regret to add that this is not a solitary case of sheep + being affected by the cattle plague. I learned that some + sheep were supposed to be similarly affected belonging to + Mr. R. J. H. Harvey, M.P., on his estate at Crown Point, + near Norwich. This place I also visited, and found a large + flock of upwards of 2000 lambs, among which the malady was + prevailing. A large number had been separated from the + diseased, and gave no evidence of the malady. Very many, + however, had died, and the disease was making rapid + progress. I also examined many of the dead, and found the + _post-mortem_ appearances to be identical with those seen in + the other cases spoken of in this report. + + "In this instance the malady was brought into the estate by + the purchase of some cattle, which afterwards died from the + disease, and which were unfortunately pastured with the + sheep at the time the disease manifested itself. + + "The whole matter is one of the greatest importance, and + which I lose no time in submitting to you for the + information of the Lords of the Council. + + "I have the honour to be, Sir, your most obedient servant, + + "JAS. B. SIMONDS." + + +IV. + + _General Considerations on the Ox-Typhus, and the + Recapitulation of the Symptoms._ + +We have seen the causes, the symptoms, and the cadaveric alterations of +the Bovine typhus, and we may therefore apply ourselves at present to +the consideration of its pathogenia and its nature. Only, the limits of +this book will not admit of a complete discussion of every point of this +important question of pathology; for if we desired to show in what +respect the typhus differs from, and in what respect it resembles, such +and such a morbid entity, febrile, infectious and contagious like it, +such a dissertation would require a whole volume for itself; we are +therefore obliged to keep within certain limits. + +Like every watchful physician who has applied himself to the study of +comparative pathology, we entertained our own preconceived opinions as +to the nature of this _Cattle Plague_. Arguing _a priori_ from what we +knew, from the laws of the pathogenia of those exanthematic diseases +which we have alluded to in a former chapter; from the identity of +variola in various animals; from the preventive treatment to which this +identity has led; believing that animals and man have each their typhoid +fever, as they have their variola or small-pox; considering with the +Ecole de Tours, typhoid fever as a variola of the intestinal mucous +membrane, and having proposed, in 1855,[Q] to adopt inoculation as a +preventive treatment, drawing an easy comparison between the typhus we +are now observing and the typhoid fever in man; hoping, we may say, +indeed, to find in this typhus the inoculative and preventive virus +which is required for our typhoid fever, all will understand with what +eager and vivid curiosity we have examined the entrails of the victims +struck down by this epizootia. For, if this typhus had been a genuine +typhoid fever, the bovine species which has already provided the +preventive virus for small-pox, would equally have afforded us the +preventive virus for typhoid fever. In this hypothesis, our proposal to +inoculate the typhoid fever, which up to this time has been tried on +horses only, and in experiments badly conducted, by pupils of the +Veterinary School of Lyons, was perhaps on the eve of being realised. +But we regret to say, we have been forced to submit to evidence, and to +acknowledge that the present infectious typhus is not the one we require +to provide us with the anti-typhoid virus. + +In the same manner as pathologists disagree as to the question, whether +the typhus and typhoid fever in man are one and the same disease, so +should we long debate, without coming to an agreement, as to that which +relates to the typhus and typhoid fever of the ox. We cannot pretend to +produce a reconciliation between these dissentient schools; all we +desire, is to sum up what observation has suggested to us, on account of +the practical and therapeutic interest belonging to the subject. + +For ourselves, the typhus and the typhoid fever of the ox are two +diseases of the same order, but nevertheless distinct; and the reasons +upon which we ground our opinion are suggested to us by the nature of +the intestinal lesions, the symptoms, and causes of these distempers. + +As we have already seen, the contagious typhus of the ox, at least that +of the present epizootia, is an infectious disease, which varies in the +intensity of the functional disorders and the cadaveric lesions to which +it gives rise. The typhoid fever, we mean the real one,--for there are +other intestinal exanthematic fevers which simulate it,--always localize +on the small intestines a pustulous exanthem, and in the typhus of the +ox, this pustulous exanthem and the ulcerations by which it is +succeeded, are frequently wanting. + +The real typhoid fever springs up in every country under the influence +of local causes, and is not in the same degree infectious and contagious +as the typhus proper. In fine, the typhoid fever smites many species of +animals--the horse, the pig, etc., without transmitting its contagion +with the same intensity. + +The contagious typhus of the ox appears to be more especially proper to +that animal; for in those latitudes where it developes itself other +animals are not affected by it. + +For these reasons, then, to which we could easily add many others, we +consider the typhus of the present epizootia a special and distinct type +of typhic diseases, and differing from the typhoid fever: it is the +highest expression of its class, and occupies the first degree in the +scale of infectious typhic diseases. Next to it we should place the +typhoid fever, which we admit is not often found in the ox. But +veterinary pathology is still less understood than human pathology, and +typhoid fever may perhaps be recognised in those diseases which the +former science has described under the names of _adynamic_ and _ataxic +fevers_. Besides, a persistent research among the veterinary memorials +and reports might possibly enable us to discover some instances in which +the real typhoid fever in the ox had been traced, apart from the +epizootic conditions. Here is an instance of it:-- + +Gelle, in vol. i. page 245 of the _Pathologie Bovine_, quotes the +following abstract which had been forwarded to him by one of his +brethren, on the dissection of an ox, which was made on the 10th of May, +1824:-- + +"_Duodenum._--Uniform redness of the mucous membrane, with thickening, +softening, and petechial spots. In the middle portion were discovered +some of Peyer's glands, small round pustules, whitish at the top, with +a reddish circumference. In some parts contiguous to these pustules lay +ulcerations somewhat extensive, which seemed to be the result of the +softening of the pustules which had preceded them. A dark pus issued +from these ulcerations. The inflammation by which they were attended was +diffused in some places, whilst in others it was circumscribed. In some +parts the intestinal mucous membrane was utterly destroyed. The +mesenteric glands were red and soft." + +Gelle adds:--"I have recorded this interesting narrative, as it may +perhaps serve hereafter to throw light on a point of doctrine." + +The intention which Gelle nurtured at the time, is, we see, now +fulfilled conformably with his object. + +The contagious typhus of the ox not being a real typhoid fever, we shall +not, consequently, be able to borrow from it the preventive virus for +that disease in man. But if these diseases differ, and if it is +difficult, in the present state of science, to assign to them such +distinct characters as to produce a perfect agreement among all medical +writers, we must, however, admit, that to designate the ox-typhus now +before us by the generic name of PLAGUE, after the Germans, who +have given it the name of RINDERPEST, would carry us too far +back. + +Let us acknowledge also, that the denomination of _contagious typhus_, +adopted by the French veterinary doctors, is not, any more than the +designation of TYPHUS FEVER, applied to it by English physicians, +totally free from objection. + +In truth, the various species of typhus whose characteristics we have +already given (see p. 73), are all of them febrile and contagious. +Whoever uses the word _typhus_, speaks of a contagious and febrile +malady, inasmuch as we cannot conceive typhus without its +accompaniments, fever and contagion. But as the prevailing +characteristic of this infectious disease is, above all, its +_contagion_, we have preferred to adopt the name of _contagious typhus_, +without, however, deceiving ourselves as to the value of the +denomination. The final elucidation has not yet been found for these +diseases; at some future day they will be methodically divided and +arranged, and each of them will then receive a special title, which will +remove from the mind that vague uncertainty which at present we regret. + +But if some faults of doctrine are open to debate, no doubt whatever can +exist in the mind as to the morbid individuality of ox-typhus, or the +general conditions of its pathogenia; and we are able to deduce from the +preceding explanation, the following conclusions as so many propositions +definitively settled:-- + +1st. The typhus of the ox is a disease essentially infectious, which is +produced by the absorption of the morbigenous miasma in the air. + +2nd. This typhic miasma is absorbed and engendered by the ox, under the +influence of a number of special deleterious causes. + +3rd. When the miasma has been absorbed and incubation produced, the +disease itself is but a supreme effort of nature--a struggle between the +vital forces and the morbid evolution of the poison, in order to guard +and defend life against the danger which threatens it. + +4th. A malady essentially general, _totius substantiae_, it directs its +action, in different degrees, over the whole structure, but chiefly on +the nervous centres, on the organs of respiration, and on the digestive +apparatus. + +5th. Its progress is regular; to the latest period of incubation it +succeeds that of the general poisoning of the blood--that of the pyrexia +of general fever--which for a time stops up all the secretions. Then, +the morbid flux is localized according to particular predispositions: +either on the nervous centres, when the animal is struck down at the +outbreak; or on the lungs, when the respiratory derangements become the +leading symptoms; or on the digestive channels, when the train of +typhoid phenomena is observable. + +6th. The period of acute inflammation, which had dried up the sources of +secretion, gives place to that of the depurative and critical +exhalations or secretions; from every mucous membrane, from every +outlet, there issues a mucous discharge, which at first is thin and +clear, but afterwards becomes thick and purulent, and endowed with the +most infectious properties. The intestinal mucous membrane, smitten with +a particular lesion, becomes the seat of a flux extremely copious and +intolerably fetid. Gases, and occasionally purulent deposits, are +developed in the cellular tissue beneath the skin. + +7th. The organism or physical frame, disturbed in the very centres of +life, undergoes a general transformation, a kind of organic +decomposition beforehand, and all the symptoms of reaction are followed +by a period of wasting atony and adynamia, which usher in dissolution or +life's extinction. + +8th. Finally, throughout the whole course of the distemper, one special +functional derangement--_stupor_--has been witnessed as the predominant +symptom, the nervous system being in a manner annihilated in its +functions in consequence of the general infection. + +Such are, in a brief outline, the principal symptoms of this typhus, +which, when once engrafted on the economy, pursues its fatal march, and +no treatment can then arrest its evolution. As in small-pox, so in +typhoid fever and in most general disorders, Nature for a time must be +allowed to exercise her new functions, which succeed each other in due +course, and which the physician must not stop; for if he did, he would +accelerate death; but he must watch with a vigilant eye, in order to +assist the vital powers. + +The medical man, satisfied with these facts, will therefore abandon the +chimerical hope of finding a specific remedy for such a disease. The +virus once absorbed, the frame will endure, and fatally endure, all the +morbid phenomena which must produce and succeed each other. _Against +such a poison no other antidote exists than the poison itself._ And this +will be easily understood. What necessity have we for a specific remedy +to resist a distemper, which carries within itself its preventive +treatment? If it germinates and is propagated, let us not accuse Nature +and render her responsible; our own blindness, the lack of a community +of interests among the people, our social institutions, the still +imperfect state of the exact sciences, &c., amply explain how it is +that we have not yet employed the effectual means we possess, not of +curing it, but preventing it. If we could have our choice between +prevention and cure, should we not naturally take the former? + +Indeed, the sources, the causes which generate the typhic miasma, are +thoroughly well known to us, and these we can avoid. The developed +miasms hang suspended in the air; we may, perhaps, one day destroy them, +if not in the outer atmosphere, at least in the stalls and sheds where +the animals inhale and absorb them. In fine, if we are powerless to +arrest the fell disease when its periods revolve, we may hope at some +future time to act with greater efficiency upon it during its period of +incubation. + +On the other hand, if this formidable disease cannot be stopped in its +progress, does it follow that we should not treat it at all? Certainly +not! Far be such a heresy from our thoughts. What would be the +consequence, if we left to their fate the sufferers from the small-pox, +from typhoid fever, and from typhus itself, instead of watching over +them with the utmost solicitude? If the physician, the enlightened +interpreter of morbid phenomena, did not direct them with a bold and +fearless hand, but abandoned Nature to her helpless course, why, +necessarily, every patient would die, whereas a large number are now +saved. + +That which is true in the case of man, is likewise true in the case of +animals: we are bound to treat them when they are ill. If to-day we +think it more expeditious and more profitable to exterminate them, we +certainly neglect our duty. We are the sovereign masters of animals; +they are the companions of our toils and pleasures, their lives must be +given to preserve our own; but on their well-being and their happiness +our own well-being and happiness also depend. They will return to us the +sufferings and diseases of which they die a hundred times over. Like +ourselves, they die of consumptive, tubercular, cancerous, eruptive, +typhoid, and parasitical diseases. And who can tell whether they have +not communicated these disorders to man, who was, perhaps, originally +exempt from them; and whether they do not continually communicate them +to him? + +What noble pages might be written on the close connexion which exists +between all organized beings, both physically and morally! Let us love +these animals, let us treat them with kindness, and all our other +qualities will be raised by so doing. + +But as a man must belong to the time he lives in, we will take up for a +moment with the doctrines of the economists; we will tolerate the +extermination of diseased animals, as a painful necessity. Our duty is +to seek in the study of the diseases of animals _and in their cure_, the +cure of the disorders which afflict the human species. We shall, +therefore, now proceed to consider the subject of the treatment of +horned cattle, both as relates to preventive and curative medication. + +FOOTNOTES: + +[O] Mr. Simonds has for three months had under his observation a cow +which has lived with impunity among animals sick and dying of the +typhus. And a young calf did not contract the disease for more than +three weeks. + +[P] Another instance of the fatal effects of the terrible disease now +ravaging our flocks and herds of cattle, and resulting in the death of a +veterinary surgeon, has just occurred in the town of Sudbury, Suffolk. + +Last week the epidemic made its appearance in the stock-yard of Mr. +Ruffell, farmer, Melford, and the cases were attended by Mr. Robert John +Plumbly, veterinary surgeon, Sudbury. On Thursday a cow, which was +evidently suffering from the disease, was brought out and shot by Mr. +Plumbly, who afterwards made a partial _post-mortem_ examination of the +carcase. In doing so with a small scalpel his shirt-sleeves became +saturated with blood, &c. from the animal. He returned home, and the +same day was attacked with sickness and acute pains in the head and +chest, accompanied with a soreness in the bones generally. On the +following day he appeared somewhat better, and was able to attend to his +duties, but became worse towards evening, and was confined to his house +on the following day. He considered that he was merely suffering from +the effects of a severe cold, and did not call in medical assistance +till Saturday night. He slept well that night, and seemed somewhat +better on Sunday morning. About two o'clock in the afternoon he got out +of his bed to have it made, when he appeared comparatively strong and in +good spirits; but almost immediately afterwards he was taken in what +seemed to be a fit, and expired in a few minutes, before the surgeon, +who only lived next door, could come to his assistance. It was thought +that death had resulted from apoplexy, and a medical certificate to that +effect was given. Rumours, however, soon becoming current that Mr. +Plumbly's death was caused by the cattle plague, the borough coroner (R. +Ransom, Esq.) directed a _post-mortem_ examination to be made. But, by +this time, so rapid was the spread of the virus through the system that +the body appeared perfectly plague-stricken, and by Tuesday morning, +when the surgeons arrived to examine it, and it was taken out of the +coffin, the corpse scarcely retained the semblance of a human being, the +head and trunk being much swollen and black in colour, the features +quite undistinguishable, and all the flesh converted into a putrid +jelly-like mass. The tissues were completely disintegrated, so that it +was utterly impossible to make any examination. + +An inquest was held on Tuesday afternoon, at the court room, Town Hall, +before the coroner, R. Ransom, Esq., and a jury; Mr. Joseph Barker, +chemist, being chosen foreman. The mayor (S. Higgs, Esq.) and other +gentlemen were present during the whole of the inquiry, which lasted +four hours. + +The jury went and viewed the body, which lay in an outhouse, but were so +overcome with the fearful spectacle that they were permitted by the +coroner to retire to partake of stimulants before they could further +proceed with the inquiry. + +The first witness called was Mr. William Brown, veterinary surgeon, and +partner with the deceased, who deposed to having gone with him to Mr. +Ruffell's farm at Long Melford, on Thursday last, to examine several +cows down with the cattle plague. One was brought out and shot by the +deceased, who proceeded to examine the intestines and viscera, which did +not present the appearances usually observable in advanced stages of the +disease, there being but slight ulceration of the coats of the stomach +and bowels. The lungs were not examined, as the deceased had only a +small scalpel with him. In making incisions in the body the +shirt-sleeves of the deceased became covered with blood, but he did not +prick or cut himself. + +Henrietta Dansie, nurse, was examined, and said that deceased had been +suffering from boils on his right arm, one of which she had poulticed on +Wednesday, the day before he had examined the diseased animal. He +removed the poultice himself, but declined to put on a plaster as the +place was a small one, although not healed. He changed his linen on his +return from Melford; but the same afternoon he was taken with sickness +and vomiting, and complained of acute pains in his head and bones. On +Sunday afternoon, shortly before he died, he wished to have his bed +made, and got out and stood whilst it was being done. He then complained +of faintness, and got into bed again, and witness to revive him washed +his face and hands; in doing so she observed that the nails of one of +the hands which had lain in the bed were turning black. She was about to +give him some pills when she noticed a sudden change come over him; and +thinking he was going to faint or have a fit, she rang for assistance +and went herself for the doctor, who, being from home, another surgeon +residing next door was called in, but by this time the unfortunate +gentleman was quite dead. + +Mr. Maurice Mason, surgeon, said he was called in to see the deceased +the night before he died, and visited him again on Sunday morning, and +ordered him a lotion and leeches for his head and effervescing drinks +(the leeches were not applied). From the appearance of the body and the +evidence which had been adduced, witness was of opinion that the death +of the deceased was caused by the absorption of poisonous virus from the +dead beast. + +Mr. W. B. Smith, surgeon, gave similar evidence, and added that the +tissues of the body were so disintegrated that it would have been +utterly impossible to have made a _post-mortem_ examination. + +After half an hour's consultation the jury returned a verdict, "that +deceased died from the effects of the absorption of virus or poison into +his system upon the occasion of his making a _post-mortem_ examination +of a cow which had died from a certain disease called the cattle +plague." + +The sad occurrence has caused much sensation in the town, the deceased, +who was only 23 years of age, being well known and much respected. + + +[Q] "Appel a des Experiences dans le but d'etablir le Traitement +Preservatif de la Fievre Typhoide et des Maladies infectieuses +inrecidivables, par l'inoculation de leurs produits morbides." Memoire +lu a l'Institut, le 8 Octobre, 1855. Insere dans la Gazette Hebdomadaire +de Medecine. Paris. + + + + +CHAPTER IV. + +_Treatment and Cure of the Ox-Typhus._ + + +In now addressing ourselves to the treatment, and, as far as human +agency can effect it, to the cure, of this insidious distemper, we +cannot conceal from ourselves, that this is the most difficult, the most +delicate, and, at the same time, the most important division of our +work; for it is to this part, above all, that attention will be +directed. This portion of our task, therefore, will prove especially +arduous; and nothing can give a better notion of the difficulties we +shall have to encounter than the many fruitless attempts which, for +several months past, have been made to overcome them by many ardent +inquirers, stimulated by the best possible intentions. + +This, then, is the moment--if we may be allowed the metaphor--to take +the bull by the horns; and we do so without hesitation. If, like so many +others, we are baffled and overcome in this unequal struggle--if our +strength is not on a level with our desires--we trust we shall be +pardoned. + +Several paths leading to the same end may be followed in this exposition +of the treatment of ox-typhus. After mature reflection, we shall adopt +the one, which will allow us to take the disease at its birth, _ab ovo_; +to study it in all its phases, in its first and second causes, and then +in the successive periods of its development. + +In this manner, we shall be able to give an account of each fact of real +importance mentioned in the foregoing pages, and to comprise within the +treatment whatever is connected either directly or indirectly with the +disease. + +Thus we will relate in so many separate articles,-- + +1st. The means and measures to be employed to meet and resist the first +local causes which may generate the typhus, then the secondary causes +which serve to propagate it. + +2nd. The means of preventing the spread of the disease to animals still +in good health. + +3rd. The means of treating it at its different periods, from the period +of incubation to that of its decline. + +4th. Finally, we shall insert the laws and sanitary regulations which +have been published in England relative to this disease. + +As will be seen, by adopting this method, the whole matter will be +considered consecutively and in regular order; and the reader will +understand that when such a phase of the malady is developed it is +because the preceding one, which is the cause of it, has not been +effectually contended with. + + +I. + + _Means and Measures to be employed to resist the Causes of + the Contagious Typhus of the Bovine Species._ + +We have shown fully and explicitly in what countries of the globe, and +in what particular conditions, the typhus is generated among oxen. We +know that this dire disease has its focus on the banks of great rivers +or lakes, which are periodically overflowed, and on which is deposited a +slime teeming with organic matter; in marshy plains, where the same +natural impurities are fostered; and that these first hotbeds of the +evil are found in China, in India, in America, in Africa, as well as on +the shores of the Black Sea. A spirit of observation which delights in +measuring the phenomena of nature with the contracted compass of its own +short views and conceptions, could alone have imagined that the +ox-typhus was only to be found originally in the steppes of Hungary and +Russia, and that the bovine species of those countries, thanks to a +special organization, was alone capable of generating the typhus. + +Since we know, then, in what conditions this disease is developed, and +especially in what manner it is propagated in Europe, it is not +impossible now, when nations are united by the means of quick and easy +communication, by commercial treaties, and by the mutual relations of +science, to examine what measures might be taken to modify and control +these conditions. A commission formed for this purpose, a scientific +congress, would be able to make on the spot a study of all the +circumstances which favour the development of typhus, and the result of +their reports would enlighten the peoples as to the causes which produce +it and from which they are first to suffer. They would be recommended to +choose as pastures the healthiest places, to withdraw their cattle at +certain seasons from those plots of ground which are baleful to them; +new systems of agriculture would be planned and tried, &c. These +questions being carefully examined, might lead to important results; nor +can we understand how, in the age in which we live, the same +indifference and apathy as prevailed in the past should be maintained in +presence of the positive and permanent causes of this infectious +disease, whose contagion, as we now see by many proofs, may extend at +once to so large a portion of Europe. There is now something to be done +in this matter; it is the duty of the governments to deal with it +effectually, and to take serious measures to destroy the evil radically, +if radically it can be destroyed, and, if not, to alleviate its +pernicious effects as much as possible. + +Moreover, many breeders of cattle have not waited until now to guard +against some of the first causes of the typhus: already they give the +animals rock salt, ferruginous and arsenical preparations, but all this +is done without method, and according to each man's will and pleasure. +It would, therefore, be necessary to institute regulations, and to see +them carried out and practised under the superintendence of public +functionaries, armed with sufficient power and authority. + +These measures having been taken, others no less indispensable ought to +follow. They should determine for the herds of cattle intended for +exportation, the ways and channels they must travel by to go to any +central part or to any railway station; and there the inspectors on duty +should mark every animal that passes out of the district he is leaving. +Heavy penalties should be inflicted on all who might infringe these +rules. + +These precautions would contribute in part to arrest the propagation of +the complaint; but there is another measure more radical and effectual, +which should be taken in order to prevent its extension--we mean +inoculation, which has met with complete success in some of the +governments of Russia. + +Thus we see, there are powerful means of withstanding the production of +the disease in its focus, or generative bed, and likewise its extension +among the herds of neighbouring countries; and these latter might render +them in some sort obligatory, by refusing most rigidly to admit to their +markets, as in Italy has sometimes been done, every head of cattle which +was not marked as inoculated or which was not furnished with a permit of +health. + +It is easy to conceive that those countries wherein the ox-typhus has +its birth, and for which the breeding of cattle and their exportation +are a great source of wealth, would soon feel that they are more +interested than any other in stifling the contagion in its focus, and in +affording to those countries that receive their herds, every security +and guarantee which they have a right to expect. Interest in this case +coming to the help of common sense, very satisfactory results would in +course of time be obtained. + +Moreover, we are conscious that we are here dealing with very +complicated questions; for, though in a book they may seem simple and +easy, their application is a matter of extreme difficulty. We know too +well that these preventive measures for protecting animals will meet +with many obstacles, and only be adopted at last with tardy reluctance, +since man himself continues in some respect indifferent to the causes +which spread about the fearful epidemics to which he falls a victim in +consequence of his neglect. + +In truth, it is well known that the cholera of the present day--that +much more serious _plague_--had its origin on the banks of the Red Sea, +amidst the infectious miasmata developed near Mecca, where thousands of +pilgrims who had died of fatigue and privation, and hundreds of +thousands of sheep butchered and religiously offered up in sacrifice, +have, beneath a torrid heat, generated the choleraic miasma, which +formerly was supposed to be produced exclusively on the banks of the +Ganges. This fact duly ascertained and proved, we might suppose that the +governments of the different nations among which the cholera is about to +extend its ravages, were indignant and had complained at thus being +smitten with a scourge, due to the careless ignorance and sordid avidity +of some official of the Turkish Government. But we should be mistaken. + +No! every one hoped at first that he, at least, would be spared by the +contagion, and the authorities did nothing to resist the evil but adopt +the old course of _quarantine_--a remedy more illusory now than ever, +since the nations are in constant communication, either in their own +persons or by the exchange of their commodities; and consequently, the +epidemic is pursuing its invading course from week to week. + +That which is being done for the cholera gives us a scale by which we +may estimate the efforts which will be made to arrest the generation and +the contagion of the cattle typhus.[R] + +We are certainly bound to resist the introduction of horned cattle +tainted with typhus; but in the conditions amidst which they live, some +of them may bear the seeds of the distemper, even whilst they appear in +perfect health, and therefore able to endure the fatigue of a long +journey. + +Now, in order to avoid exciting the incubation of the typhus during +their transit either to Finland, Holland, France, or England, it must +never be forgotten that these animals are gifted with a nervous +sensibility of wonderful acuteness, joined to the weakest vital +resistance. Care must be taken to husband their strength, to give them a +choice distribution of food easy of assimilation; barley-meal, or other +grains, must be mixed up with their drink; they must be protected from +the changes of weather; they must have room enough and air enough in the +locomotive stalls on the railway trains and on board ship. + +We pass over in silence the hygienic measures to be taken in order to +keep these vehicles of transit in a proper sanitary state: the sanitary +police regulations inserted further on will make them sufficiently +known. + +All these measures having been taken to meet and withstand distant +causes and dangers, let us now direct our attention to those local +causes which strike our eyes, and which likewise have their share of +influence in propagating the disease. Thus, whenever an inclement season +comes to deprive the herbivorous animals of sufficient pasture, or to +deteriorate its natural qualities, we are bound to remedy this change, +and to increase the cares we devote to them; for these frail and +helpless creatures, immediately feel and suffer from the effects of a +sustenance less than usually restorative. Under such circumstances, we +must make exceptional sacrifices; when they return from feeding on the +grass, we should give them some additional fodder, or roots of a +generous quality. We must imitate the regimen used in the country of the +steppes, by adding to their forage a solution of marine salt, or a +solution of sulphate of iron. Day by day we must give to the weakest and +least fed cattle, a ration consisting of bruised oats, pounded juniper +berries, gentian, sulphate of iron, and carbonate of soda. + +For, if we neglect to take those measures which are required to prevent +among herbivorous animals the development of those ordinary epizootias, +which every year are generated on our own soil, they will certainly +afford a favourable seat to the typhic miasma transmitted by foreign +animals, or exceptionally generated by themselves. These cares and +attentions must be greatly increased, when the foreign epizootia, has +spread itself, as in the present instance, among our flocks and herds. +Then, indeed, we must be careful not to load these creatures with +pampering food for the purpose of fattening them. For it may be +profitable, and the breeder may plume himself, on having produced an +adipose monstrosity to such a degree as to bury, for instance, a pig's +head in the fleshy exuberance of his thorax; but such a derogation from +the laws of nature borders closely on disease, and assuredly such an +unnatural accumulation, predisposes the glutted animals to epizootic +diseases in general. + +The water given them to drink must be attended to with particular +solicitude. It should never be drawn up from ponds or stagnant rivers. +The animals kept in the pasture grounds should always find at their +disposal, in receptacles intended for their use, a supply of pure fresh +water. + +After these precautions with respect to their food and sustenance, +attention must next be directed to the hygienic conditions required by +the animal. Every morning he should be cleaned, washed, brushed, and +dried; what is every day done for the horse must now be done for the ox. +These unusual cares will be most salutary to him, and greatly increase +his vital resistance. + +The animal thus protected in his food and particular necessities, +attention must next be directed to the stalls and sheds. Over-crowding +must be carefully avoided; the proper cube of air for breathing must be +measured out for each head of cattle; every day the latter must be +carried out into the open air; the floor of the stall or shed must first +be thoroughly cleansed and washed out, after which it must be sprinkled +with a solution of chloride of lime. If the stall is not well aired, a +little straw should be burned on the ground, to improve the atmosphere, +or else branches of resinous trees, or juniper berries may be used. In +some cases aromatic fumigations of sage, rosemary, or mint, boiled in +water, are employed, the balsamic vapours which arise therefrom being at +once tonic and purifying. During the night a tub, containing pitch and +tar, should be left in the stall, or a large piece of camphor should be +suspended from the ceiling. Vinegar may be spilt on a piece of red-hot +iron, or powder of sulphur may be burned into sulphuric gas and diffuse +its vapours through the stall or shed. This excellent parasiticide may +perhaps be equally endowed with anti-typhic properties. + +Finally, when this fatal epizootia is ravaging the country, every farmer +and agriculturist must carefully abstain from mixing with his herds any +cattle which have been bought either at fairs or markets; he must take +care, conformably with the directions issued by the Privy Council, (to +which we refer the reader for more ample details,) to avoid all contact +both direct and indirect with horned cattle tainted with the typhus, as +he might himself become an instrument of the contagion.--Let him never +forget that to take as the guide for his actions in these times of +calamity his private and personal interest, is the greatest crime a man +can commit. Let him strive, therefore, to assist the authorities in the +measures which they have taken for the interest of all. + + +II. + +Now that we have examined the measures which prudence directs us to take +to defend ourselves against the causes which produce and propagate +typhus, let us think of the means of preventing it, when the contagion +threatens to diffuse itself over a whole kingdom, as at present it is +doing in England. + +When, on the 19th of last June, it was believed that the typhus or +Cattle Plague, as they continue to call it, had effected its invasion in +England, the Government, informed by professional men of the serious +danger to which the interests of the country would be exposed, if the +disease should spread, might have considered this distemper not as a +question of private interest, but as one of public and national concern. +It might at the outset have given to this epizootia all the significancy +of a public calamity, have looked upon it as the invasion of an enemy +threatening to destroy its territory, and have employed every possible +means to stifle it at its birth. + +We well know that the English Government, derived as it is rather from +political than from religious and social changes, is at once +monarchical, aristocratic, and partially democratic, and for that reason +embarrassed in its working by so many wheels. Its authority is scattered +and divided, whilst the respect ascribed to the prerogatives of each +distinct public power is the safeguard of the State. In the absence of +both Houses during the recess, it could take no resolution as to ways +and means; for the difficulties on this unhappy occasion, we cannot too +often repeat it, are reduced to a question of money. Deprived of the +requisite authority, it was unable to do more than exhume the old laws +on the matter and ordain new ones. And yet, the impotence of the +Government was not perhaps so great as is imagined; for whilst it +suffered the typhus almost unmolested to devastate the country, it very +justly, and in the name of the public interest, took vigorous and +effectual measures to stamp out another epidemic--the rash and insane +conspiracy of the Fenians. It stood still and would not authorize +domiciliary visits in stables and stalls, nor the seizure of sick +animals, but it did not falter a moment at the domiciliary visits and +incarceration of insurgent citizens meditating mischief, so that in +this instance, the privilege of immunity has been given to the brute +creation. Everybody, both in England and out of England, admires their +vigour and despatch in stifling the insurrection in its bud. But why not +act with equal promptitude in the case of an epizootia? + +Arming itself, in this manner, in the public interest, and with +sufficient power, the Government might have appointed an executive +commission, with the Lord Mayor as president. Such a commission would +have applied itself at once to the consideration and studious +examination of the subject in all its bearings, and would have proposed +prompt and energetic measures, which the Government, with equal +despatch, would have confirmed by giving to them the authority of law, +as they have since tardily done. A fund, which, for the wealth of +England, would not have been considerable, 250,000_l._--the cost of a +few Armstrong guns--might have been placed at the disposal of this +Board, to enable its directors to meet and provide for, without delay, +every just claim and want arising from the scourge. + +An auxiliary commission, exclusively medical, and consisting of medical +and veterinary doctors, might have been formed conjointly with the +former, and every preventive measure, considered by them as necessary to +stamp out the complaint at the outbreak, after it had been proposed by +the medical board, and submitted to the executive commission, and by +them to the Home Secretary, might have been acted upon by law within +twenty-four hours. + +Taken unawares, and the mode of treating the sick animals not being +known at first, they would have been reduced to the cruel necessity of +exterminating at once all tainted cattle, as well as those belonging to +tainted herds, but not without compensating the owners of those +cattle.[S] + +They would have sent two physicians to Russia and Hungary, to observe +and study the preventive and curative medication, especially their mode +of inoculation, and thanks to the rapid locomotion of these times, +twenty days would have been sufficient for this foreign exploration. +The physicians constituting the medical board should have been +authorized to seize any beast tainted with the typhus; a company should +have been charged to collect and keep ready for the public service, at +the four quarters of London, an ample retinue of horses, closed +carriages, and working men, to convey at all hours of the day and night +the carcases of the slaughtered animals to the respective spots, where +long and deep trenches had been dug to receive them. Each carcase before +burial to have been well sprinkled with chloride of lime. + +By taking this course, every one's interest would have been respected, +as much as can be desired when a great calamity threatens a country; +besides, in doing so, the present ministers would but have followed the +example of the Government (with regard to compensation), during the +epizootia of the eighteenth century. The proprietors who had thus +received, not the full and absolute price, but a sum sufficiently +remunerative for their sacrificed cattle, would have assisted the +authorities, and thereby would have served the common interest, because +their sick cattle, perishing every hour within their stalls and sheds, +were no longer a real source of embarrassment and ruin. They would not +have been obliged to drive them to market to get what they could out of +them and disencumber themselves. The most active cause of the contagion +would by this means have been prevented. + +This allowance having been made for the most pressing dangers, attention +should next have been directed to a matter no less important--we mean +the treatment and cure of this distemper; for we will never admit that +England can have fallen back a century, and that whilst those +enlightened men--Malcolm Flemming and Layard--proposed and tried to cure +and prevent ox-typhus in 1757, we, in 1865, shall have been reduced to +the horrible alternative, the repugnant barbarity, of the general and +indiscriminate extermination of the tainted cattle. + +Whilst, therefore, the treatment of the typhus would have been studied +on the spot, and the most urgent measures would have been taken to +withstand the propagation of the evil, they would have established, a +few miles from London and on the northern side, in the direction of the +great cattle market, a number of hospitals or sanitariums, and, as far +as possible, within a park. These hospitals, constructed of wood, +containing, besides stables and sheds, a slaughter-house, a +dwelling-house for the staff of employes, a laboratory stocked with all +the physical and chemical instruments required, &c., would in two or +three weeks have been sufficiently prepared to receive a certain number +of cattle. + +Provided with these advantages and opportunities, a permanent stage of +operation would have been raised on which trials and experiments might +have been made with every chance of fruitful results. In these +sanitariums, for instance, the most practical physicians and +veterinarians might have entered upon a systematic course of treatment, +dividing the bovine patients into classes, according to their periods of +disease, their age, &c.; and trying some particular mode of treatment, +some remedy considered as effectual, alternately, upon each of these +classes of tainted cattle. These experiments, having been made under +circumstances so favourable, would have enabled the faculty to +establish a medical basis, which, if not infallible, would have been +relatively efficacious, and might have saved a large number of the +infected animals. + +Whilst thus fixing their attention on the cure of the sick animals, +these experimentalists would have carefully studied and practised the +preventive treatment by inoculation, availing themselves both of +Layard's hints and recommendations and of the practical knowledge +acquired by the medical expedition to the steppes, which would by that +time have returned from their mission. They would have selected animals +smitten with the genuine typhus, of the typhoid and intestinal form, in +_the third period_, whilst the depurative and critical secretions are +running from the mucous membranes; they would have gathered the virus +from its springs of infection or from its purulent subcutaneous deposits +or from the serum of the blood. + +On the other hand, they might have chosen four heifers, of good +constitutions and healthy, and these they might have prepared, according +to Layard's advice, for inoculation, by a special treatment, and by +hygienic and medical cares. On some of these the inoculation would have +been made near the tail, according to the subcutaneous process, with a +lancet charged with typhic virus; on others, a crucial incision, or +cross-cut, would have been made on the crupper. But, to speak truth, we +cannot do better than Layard, whose ingenious treatment, with all due +deference to a certain veterinarian of our day, deserves a very +different epithet than that of being amusing.[T] Layard says:-- + + "That nothing may be omitted which in any shape can + contribute to the success of inoculation, due attention + should be paid to the constitution and state of the beast, + no less in this practice on the cattle than on the human + species. Undoubtedly the young, healthy, and strong bid + fairer for a good issue than the old, sickly, and feeble; + each of these different constitutions demand a particular + treatment, even in the method of preparation; and however + trifling it may seem to many--the urging a necessity of + preparation--I will venture to affirm that I have seen + excellent effects arising from a rational preparation, and + fatal events from want of preparation. I have likewise been + witness of unfavourable turns, merely from an injudicious + preparation. + + "The beasts which are sanguine require moderate bleeding; + those that have but a small share of blood must have none + drawn. The strong must, besides moderate bleeding and + purging, be kept on light diet and their body kept open. + Thus, scalded bran, mixed with their hay and chaff; will + cool them. The weakly, and such as are inclined to scour, + must be kept on dry fodder, and have peas and beans given + them to strengthen them. A mess of malt, or a quart of warm + ale, with a few spices, will be very suitable for them. + + "Whatever diseases the cattle be affected with, if time will + permit, they are first to be removed. + + "The cattle to be inoculated are first to be well washed, + rubbed dry, and then curried, to remove all the filth from + the hair and skin. Then they are to be placed in a spacious + barn or stable, where the air is temperate and no cold can + come to them. There they are to be prepared according to the + direction already given, foddered with good sweet hay, and + watered with clear spring water; and if the distemper be not + near they may be turned out into the air, near the barn or + stable, and may stay there a few hours in the middle of the + day. + + "When it appears that the cattle are in perfect health, free + from any infection or other disease, brisk and lively, + neither costive nor scouring, and chewing their cud, then + the operation may be safely undertaken, and henceforth they + must be confined to the barn. + + "Since there is observed to follow the greatest flow of the + contagious and putrid particles separated from the blood, + wherever the infectious matter makes an impression at first, + particular care must be taken not to inoculate near such + vital parts as the heart and lungs, nor near the womb, if a + cow with calf be inoculated; for, though rowels are properly + applied in the dewlaps, to draw off the pestilential humour + from the breast, and in other cases beasts are frequently + rowelled in the flanks,--yet in this operation, as matter is + inserted by these channels into the neighbouring vessels, + those vital parts, or the womb, might become the chief seat + of the disease, and the event prove fatal. + + "To prevent such accidents, human beings have been + inoculated on the arms and legs, and now-a-days the arms are + found sufficient. I would recommend that the cattle should + be inoculated about the middle of the shoulders or buttocks, + on both sides, to have the benefit of two drains. The skin + is to be cut lengthways two inches, deep enough for the + blood to start, but not to bleed much. In this incision is + to be put a dossil or pledget of tow, dipped in the matter + of a boil full ripe, opened in the back of a young calf + recovering from the distemper. It may not be amiss to stitch + up the wound, to keep the tow in, and let it remain + forty-eight hours. Then the stitches are to be cut, the tow + taken out, and the wound dressed with yellow basilicon + ointment, or one made with turpentine and yolk of egg, + spread on pledgets of tow. These dressings are to be + continued during the whole illness, and till after the + recovery of the beast, to promote the discharge; and then + the wound may be healed with the cerate of lapis + calaminaris, or any other. + + "On the third day after inoculation, the discolouring of the + wound, whose lips appear grey and swollen, will be a sign + that the inoculation has succeeded; but the beasts, as + Professor Swenke informs us, did not fall ill till the sixth + day, which answers exactly to the observations daily made in + the inoculating of children. Yet the Professor adds that on + the third day a costiveness came on, which was removed by + giving each calf three ounces of Epsom salts. + + "No sooner do the symptoms of heaviness and stupidity appear + than the beasts must have a light covering thrown over them, + and at night fastened loosely. They must be rubbed morning + and evening, and curried, till the boils begin to rise; warm + hay-water and vinegar-whey must be given plentifully. Should + the beasts require more nourishment, dry meat, such as hay, + with a little bran, may be offered. I should be very + cautious in giving milk-pottage, even after the boils and + pimples had all come out, for fear of bringing on a + scouring. However, this caution is proper, that whenever + milk-pottage be given the vinegar-whey is to be omitted for + obvious reasons. In cases of accident, the same attention is + to be observed in the disease by inoculation as in the + natural way, and the medicines recommended are the same I + would use; but by inoculation there seldom is a call for + any, so favourably does the distemper proceed through its + several stages. + + "The crisis being over, it will be proper to purge the + cattle, to air them by degrees, and to have the same regard + in the management of them as is laid down in the chapter on + the method of cure." + +The typhic virus is so highly infectious and poisonous that the first +animals inoculated would have all died; it would have been necessary to +inoculate successively a number of animals with the virus derived from +the first inoculation, and transmitted from an inoculated animal to a +healthy one, by which means they would have acquired a virus of the +first, second, third generation, and so on. These inoculations having +always been made on four animals at a time; on two of them, the disease +would have been left to take its own course, in order that the +experimentalists might watch its progress and development, and the two +others would have supplied the virus for inoculation. + +At the third or fourth generation, the virus, modified and attenuated in +its infectious principles, would no longer have been mortal in its +effects, as experience has proved in Russia. Then the inoculated +animals, placed under the control of hygienic cares and a few purgative +and tonic medications, would have passed from convalescence to health. +The virus thus attenuated would have supplied the means of a practical +inoculation on a large scale to all healthy animals. + +Proceeding thus, they would, moreover, but have followed the method +adopted in those times of epidemic and epizootia when the small-pox is +raging. On those occasions, we subject our sick patients to vaccination +or revaccination; we inoculate the variola in our sheep threatened with +the contagion; we pursue the same course in cases of epizootia, of +peripneumonia. And truly, that which it is reasonable to do in one case +may be generalized and applied to a greater number. + +The experiment we have suggested might, perhaps, have been long and +difficult, nay, even costly, but we should have established, after a +certain time, the rational method of this preventive treatment, and have +distributed the same throughout the country. Veterinarians would have +formed in particular districts their centre of operation, in which the +preventive virus might have been produced, and they might have gone from +farm-house to farm-house to inoculate all the cattle within them. + +From these facts and observations made by the physicians, precious +documents would have been derived; and if, contrary to all expectation, +success had not justified every hope, we should have bequeathed to +future generations facts and experiences which would have been of the +most useful character to them and full of instruction. Thus it is that +science advances and progress is accomplished. + +If all that we have just indicated as a realizable matter had been done, +in effect, England would have afforded in this, as she has so often done +in other cases, a noble example to be followed, and would have acquired +a new title to the admiration of other nations. + +But, unfortunately it has not been so: silence has succeeded to +eloquence at Guildhall, and the meetings at the Mansion-house have +flickered away. That which was held on the 27th of September, seems +likely to be the last of them.[U] + +The subscriptions which, in spite of all the praiseworthy efforts and +earnestness of the Lord Mayor, did not reach 2000_l._, were returned to +the subscribers, so that all the attempts which have been made to +centralize the direction to be given to the various measures have proved +abortive. The plan of forming sanitariums, as well as that of +compensating the owners of cattle, have both fallen to the ground. + +What can we think of such a state of things when we see the ox-typhus +extending its ravages to sheep, and have to fear that the disease will +spread to other animal species? What serious reflections it creates in +our minds, and what awful consequences we might deduce therefrom! But +what would be the use of them? + +Let us add, however, that France, save on the recognised principle of +indemnification, and a more speedy extermination of her tainted cattle, +has shown the same deficiency as to the means of treatment as England; +whilst we have the consolation of attributing this impotence on the part +of this country to the fact that the outbreak of the epizootia has +occurred during the Parliamentary recess. + +It is, therefore, to institutions rather than to individuals that we +must ascribe the impossibility of conquering the difficulties which have +been met, and which at any other time might not have obstructed the +course of things. Far be it from us therefore to accuse of indifference +a great people renowned for their zealous promotion of public interests, +for their charity and inexhaustible philanthropy, whose innumerable +asylums have been opened to every misfortune, who support so many +hospitals and public charities by their voluntary contributions, and +who, in so many calamities, have seen some devoted heroine issue from +her retirement to assuage them. For if the Crimean war produced its lady +beneficent in the person of Florence Nightingale, all of us must allow +that if others had followed the example of Miss Burdett Coutts, who, in +a manner, has stood alone against the storm, by the facilities she has +afforded for treating and experimentalizing on the cattle smitten with +typhus, the formidable scourge might have been arrested in its focus. + + +III. + +_Curative Medication._ + +We might acquire the means of resisting the general causes which develop +the typhus; we might stop its diffusion, we might even prevent it, by +inoculating the sound and healthy animals, and yet it would be +necessary, none the less, to search for the means of curing it; for, as +in the small-pox, the preventive treatment of which we know, certain +circumstances would arise in the disease which would oblige us to treat +it. And as we are far from being able to resist the generation and +dissemination of this scourge, which reckons almost as many victims as +sufferers, it is important to make known what treatment we can oppose to +the functional derangements to which it gives rise. + +As we have already said, this typhus, when the organism has absorbed its +peccant and infectious miasma, produces a succession of disorders which +become in a manner temporary functions; it pursues its phases, its +periods; and as the functional derangements differ at these several +epochs from the development of the morbid phenomena, the course of +medicine which is employed to check them cannot always be the same. +Starting, therefore, from practical data, we will attend the disease in +its gradual advance--that is to say, in its distinct periods--and will +afterwards explain certain predominant symptoms, which, owing to their +importance, must likewise fix the attention of the careful therapeutist. + +It will be remembered that we have recognised four periods in the +regular course of typhus:-- + + 1st, a period of incubation; + 2nd, a period of initiation; + 3rd, a period of duration; + 4th, a period of decline. + +But, in the first place, before beginning the treatment, every farmer or +grazier, or cattle-owner, who keeps a certain number of cattle, should +divide his herd into several classes, in order to regulate and methodize +the cares to be given to the sick. + +Thus, he will form a first class, comprising the animals in a sound and +healthy state, having had no intercourse, either direct or indirect, +with the tainted cattle, and which he will be careful immediately to +isolate and keep apart. + +A second class must be formed of those beasts, which, though as yet +unaffected with the distemper, have, nevertheless, been exposed more or +less directly to its contagion, by living and consorting with them, or +by their contact with other animals, either at fairs or markets, or in +the ships and cattle-trucks on the railway during their transit from one +place to another. The horned cattle composing this latter class must be +carefully watched, and be made the subject of the preventive treatment, +the moment the first sign appears of the working of the incubation. + +A third class must be formed, consisting of cattle actually smitten with +the distemper. + +These divisions of animals being thus settled and separated, will +diminish the labour and the cost of treatment and the liability to +diffuse the complaint, especially when the epizootia begins to lose its +virulence. + + +_First Period--of Incubation._ + +We have said that infectious diseases, when once the frame had suffered +the effects of the poisonous miasma, pursued their fatal course, and +that, generally speaking, it was impossible after such infection to +arrest its development. We say generally, for the typhus at the outbreak +of its appearance on a virgin soil sometimes manifests itself in a +benignant manner, then it becomes more destructive, by-and-bye its +pernicious properties decline, and it in some sort goes out of itself. +One would say that the epizootia, like those it smites, has likewise its +peculiarities, its period of initiation, of duration, and of decline. +There are in consequence fixed times or epochs during which the +sufferers afford better scope for our means of action; at a given moment +the attenuated virus, having lost much of its deadly effects, ceases to +produce death, which decline is the real source of the marvellous +successes obtained by certain remedies against the epizootia. + +If it be true that the distemper at its period of duration, and at its +most critical moment, cannot be fettered, we should not be justified in +asserting positively the same, as respects the period of incubation. +Indeed, we are convinced ourselves, that if ever this disease shall be +clogged in the wheel, _if ever its specific remedy shall be discovered, +it will be within the period of incubation_, when the economy begins to +struggle with the first phenomena of the poisoning. Be that as it may, +we cannot, in epizootic times, too earnestly enjoin the owners of cattle +to submit their animals to a strict and close inspection, in order that, +when the first signs of incubation appear, they may modify the animal's +usual diet, and attack the disease at its birth, so as to render it +abortive, if the thing can be done. + +At this period we must endeavour to come to Nature's assistance, we must +shake and stir up the economy, we must unseat the morbid functions which +seek to master us, and then the vital force, thus solicited and +stimulated, may sometimes struggle with advantage. To do this +effectually, if the animal is atonic and predisposed to adynamia, if his +internal organs are relaxed, we will strengthen him by administering +every day a stimulating beverage. If he is confined to the stall we +will give him the open air, and let him graze the fields; which is a +treatment by itself for the invalid animal, so vivifying is the pure air +of the common, and so thoroughly different from the atmosphere which is +pent up within his stall. If the animal is strong, lusty, exuberant with +health, let him be purged once or twice, the purgative to be given at +intervals of twenty-four hours. (We shall give the medical formula in +the chapter addressed to farmers, graziers, &c.) + +This purgation, moreover, will correspond with the theory of those +authors who consider the evacuations as the proper means of delivering +the economy from the infectious miasms which have been absorbed. + +If the beast is plethoric, recourse should sometimes be had to bleeding, +especially in hot and dry seasons, like the one we have recently passed +through. + +These stimulative and depletive medications cannot but be favourable to +the animal, since it will anticipate the treatment to which he must be +submitted a few days later, when the disease shall have declared +itself. + +To this treatment, in some sort preventive, must be annexed an +_antimiasmatic_ beverage, either a _permanganate of potash_, or a +solution of _chlorate of potash_, or of _arsenic acid_ in powder, mixed +with some aromatized beverage, or solution of _arseniate of soda_. These +anti-typhic drinks must be discontinued on those days when the sick +cattle are purged. + +It need hardly be said, that during this period of incubation the +feeding of the cattle must be strictly attended to, and that the animal +must receive unusual hygienic care. + + +_Second Period, or that of Initiation._ + +At this period the constitution and temperament of the sick cattle must +first of all be deliberately studied, so as to ascertain fully which are +_lymphatic_, which are _nervous_, and which are _sanguine_. We must +notice the age, the sex, the state of gestation, and make allowance for +any prior complaints to which any of the sick cattle may have been +subject. For if, like certain system-mongers, we reduced the treatment +of all tainted cattle to the same mathematical formula of medication, +that is, either to bleeding or to purging exclusively, we should +certainly increase the number of victims. + +In this stage of the disease we have to contend with the derangements of +the circulation and secretions. The fever is generally intense, the +blood is inflamed or vitiated, the mucous membranes are dried up; +shiverings, alternations of cold and heat, &c., occur. We must then +mitigate these morbid phenomena either by bleeding or purging. The +bleeding must be more or less copious, according to the strength of the +animal. For, it must not be forgotten that we have several critical +phases to pass through, and if we exhaust the animal by too largely +draining him of blood, we may forfeit the success of the treatment. If +bleeding is considered unnecessary, let the sufferer be purged at once, +by administering either _sulphate of magnesia_ (_Epsom salts_), _or +sulphate of soda_ (_Glauber's salt_). These purges to be taken daily, +for two or three days, according to the way they operate. Linseed oil, +mixed in some warm beverage, may be given instead of these, or else a +mixture of rhubarb and calomel, or even a decoction of senna. Preference +should be given to saline or laxative purges, as, drastic purgatives, +such as aloes or jalap, sometimes concentrate the inflammation on the +narrow parts of the digestive channels. + +In this second stage--the period of initiation--the appetite is +generally gone, the thirst excessive; so that nutritive or solid feeding +must of course be suppressed. + +As for the drinks, they must be cold, consisting of water with +sufficient flour mixed in it to whiten it, and a little vinegar or +sulphuric acid, to acidulate it. A decoction of good hay with some +marine salt, or nitrate of potash; a decoction of pellitory or +wall-wort, of ground-ivy, or whey, or buttermilk, likewise acidulated, +and which the cattle are very partial to, will in every way be suitable +for their use. If the heat of the skin diminishes, and if congestion +appears to settle on the lungs, the drinks must be given warm, +consisting of a decoction of borage leaves, mallows, marsh-mallow, and +pellitory. In these cases, the body must be protected from chills by +overlaying it with blankets, so as to keep the mass of the blood as much +as possible on the surface, and check the tendency it has to load the +internal organs. + +By following these prescriptions, we shall answer all the conditions of +the treatment during the second period. In truth, by the process of +bleeding, we shall have reduced the heat of the fever, and prevented too +great a flow towards the nervous, pulmonary, or digestive centres. The +purgings will have acted with similar effects; and, what is more, they +will have cleared the _primae viae_, and rendered the circulation of the +abdominal apparatus more easy. In fine, the drinks will have contributed +to assuage the violence of the fever. The washing, which must be +effected with a wet sponge passed over the nose, mouth, and eyes, and +then over the skin, which must afterwards be rubbed dry, will be both +useful and pleasant to the sick animal. This cleansing will maintain the +important functions of the skin in due order. + +Some persons have advocated as most efficacious at this period +hydro-therapia, or the Water-cure, in the form of warm and cold +ablutions, vapour baths, &c. This treatment, so bracing by its revulsive +action, and the powerful influence of which we witnessed for several +years in the establishment which we superintended at Belle Vue, near +Paris, might prove of some service in ox-typhus, especially in the form +of the vapour bath; but it requires so much practice, and so incessant +and watchful a care, that it is needful to have the process attended by +an experienced practitioner. + +We must remark, in addition, that the general state of the animal, and +his desire for food, will show the degree of strictness and restraint +which must be observed in regulating his diet. His instinct must be +taken by us as a guide; and if the drinks rendered nutritive by the +addition of bran, oatmeal, barley flour, or even seed of grass pounded, +are relished by him, we must indulge his desires to some extent, in +order to keep up his strength. + + +_Third Period, or that of Duration._ + +At this stage of the distemper we must watch and follow step by step the +symptoms which attend it, and come to their relief. + +All the secretions have now resumed their course; from the mucous +membranes there occurs a copious discharge, first of all serous, then +thick and muco-purulent; the breathing may be obstructed, the +diarrhoea frequent; the air infiltrates beneath the integument. The +fever is sometimes continuous, sometimes intermittent. We must satisfy +the cravings of the vital powers by administering the same beverages as +in the preceding period. Far from checking the diarrhoea, as some +advise, we must regulate the evacuations by means of laxatives, such as +tartrate of potash, sulphate of magnesia, or sulphate of soda. It is +very essential, indeed, that the mucous membranes of the digestive +channels should be free, and not irritated by the contact of solid +alimentary substances or bilious secretions. + +If the diarrhoea be too frequent or irritating, we must give the +sufferer night and morning a clyster, consisting of bran water. + +At this period we will follow the advice given over and over again by +all the physicians of the last century, and apply cauteries with red-hot +iron, or fix one or two setons either on the dewlap, the neck, or the +thighs, and these issues must be kept open by means of basilicon +ointment. It is unquestionably of the highest importance to promote all +the depurative secretions in animals whose cellular tissue is choked up +with grease and lymph. Those only have got well in which the running has +been regular and copious, and the wasting of the flesh progressive. + +If the fever is not regular, two pills of sulphate of quinine must be +given, each pill containing one gramme, one pill in the morning, the +other during the day, in order to prevent the fit, which usually takes +place in the evening. If the state of atony, of adynamia, comes on at +this period, _acetate of ammonia_ must be given, from one to six ounces, +in a pint of water, the same to be administered in two doses; only the +acidulous or alkaline drinks must be discontinued, otherwise the acetate +of ammonia would be decomposed in its passage into the digestive +channels. Finally, the eyes, the nostrils, and the mouth must be +frequently washed with an infusion of camomile, or some other aromatic +plant. + +The setons must be kept up very carefully. If the sick animal relishes +the nutritive beverages, let him have a decoction of bread, rice, +barley, or oats. + + +_Fourth Period, or that of Decline._ + +At this stage of the disease, in which adynamia predominates, everything +must tend to support the organism. The drinks must be bitter and +stimulating; beer, with plenty of hops in it, with an addition of +powdered Peruvian bark or sulphate of iron, may be given; or a decoction +of this bark, with gentian roots, centaury leaves, and hops; or again, a +beverage may be administered night and morning, made of veterinary +theriacum, of extract of juniper and alcohol; or finally, an infusion of +aromatic plants. + +If the diarrhoea be bloody and fetid, give the animal night and +morning a clyster, consisting of a decoction of Jesuit's bark, adding +thereto a spoonful of powdered wood charcoal, pounded to the finest +powder, and passed carefully through a sieve. If the running ceases, its +return must be excited by injecting in the nostrils a spoonful of +sternutatory vinegar or smelling salts. Finally, the purulent boils must +be opened, and dressed with stimulating ointment. + +At this closing period, which determines the fate of the disease, as we +say, there is a tendency to despair of the cure. Seeing the fatal course +of most attacks, we lose heart, death seems inevitable, and we yield its +prey to its fangs. But let us not despair; let us remember that, in +these febrile infectious diseases, above all, the phenomena must almost +always proceed to the last stage of exhaustion of the vital powers to +render the cure attainable. Some patients, smitten with typhoid fever or +cholera, have owed their lives to the indefatigable tenacity of the +contest _in extremis_ between life and death. + +I still see before me a choleraic patient, whom, during the epidemic of +1849, I had left in the morning at ten o'clock, passing into the cold +period. At five o'clock I returned to see him; the whole family was in +tears, and the sheet had been thrown over the patient's head, as if he +had already breathed his last. Time was precious to me at that fell +season, and I was about to retire, when I applied my finger to the wrist +of the sufferer, and felt a faint pulsation at long intervals. I threw +my coat off directly, called for flannel and essential oil of mustard, +which I had prescribed that morning. I set the example, and instantly +the whole family helped me to rub the patient in every direction. In a +quarter of an hour the heart quickened and revived, and in less than +half an hour more the circulation resumed its course; at the end of an +hour of this obstinate struggle the vital heat began to show itself--in +a word, the patient was saved. + +We must not, therefore, give up the contest until the death of the +sufferer is fully ascertained; and the same persistency should be +practised in the case of animals smitten with the typhus. If the +circulation slackens, if the skin turns cold, take a piece of wool, coat +it with rubefacient liniment, and rub the animal therewith, more +particularly along the spine. Then give him a cordial drink, and pass +_raies de feu_ over the loins. All these appliances will help to +stimulate the nervous system, and resuscitate the exhausted powers of +life. + +If, at last, we are so fortunate as to overcome the profound adynamia +which has utterly prostrated the frame, we next shall have to sustain +the sick animal by giving him decoctions of meat with sea-salt, or +sulphate of iron added to it, or a light broth, made with meat and +bread. + +Herbivorous animals, put upon a carnivorous diet, would not generally +endure it, of course; but some of them rather incline to unctuous +beverages, and even to cooked or raw meat. All men know that certain +horse trainers give race-horses a small portion of meat, especially when +the races are coming on, in order to increase their mettle and strength. + +We remember a sheep, which we saw at the Ecole d'Alfort, during our +studies of comparative pathology and the cutaneous diseases of domestic +animals, which manifested a great liking for meat, and even ate it +ravenously like a glutton. + +In convalescence, the animal must be sent into the open air, in some +fold enclosed with bars; he must be taken every day to pasture, each day +increasing the time he is allowed to feed, and gradually he will be left +to return to his usual regimen. But still it must be observed, that in +this distemper convalescence is long and slow, and very deceitful. A too +substantial course of feeding often revives the inflammation of the +intestines by irritating ulcerations not yet healed, and more than one +animal which had been looked upon as cured has perished in its +convalescence through a lack of watchful attention. + +Herbivorous beasts, therefore, incline to and digest animal food; +consequently, we must give sick oxen meat broths, pure milk, or milk and +water. With these must be mixed wheat straw chopped small, for hay or +even oat straw would swell and distend the stomachs. + +The typhus in this epizootia is not regular in its progress and +development. Frequently the nervous or pulmonary phenomena predominate, +when the treatment, such as we have just explained, must be modified. We +must also bear in mind that nature does not divide a disease into +periods, like those we have adopted to render our exposition of the +symptoms more intelligible and the treatment itself more methodical. + +If the nervous form of the disease prevails--if the animal shows +alternations of dulness and restlessness--if, pressure on the spine is +very painful--above all, if, in bulls, for instance, there is plethora, +let the bleedings and purgings be increased in order to abate the +nervous erethismus. In this form, the violence of the attack usually +carries off the beast. Should there, however, be any chance of saving +him it will be by employing this medication, which is at once revulsive +and depletive, notwithstanding the well-known fact that bleedings, far +from relieving the nervous system, sometimes aggravate its irritability. + +A general ablution with cold water may be tried in _desperate cases_. +The animal must then be immediately well rubbed, and covered with wool, +in order to excite a thorough reaction. + +In the pulmonary form of the typhus, but only during the acute stage, +the drinks must be warm and emollient, composed of a decoction of +soothing substances, with mallows, &c.; or one of linseed, to which must +be added some oxymel of squills and opium. The purgatives must be +non-stimulating; and emetics, freely diluted, for instance, will be +very serviceable. + +At the third and fourth period in this pulmonary form of the disease, +adopt the treatment prescribed for intestinal typhus. + +We might have greatly enlarged the list of the pharmaceutic agents, but +the richer a treatment is in remedies the poorer it is in cures. We have +made choice of the simplest and safest among all the remedies advised by +experienced men, making allowance for the difficulties inherent to the +number of animals, the mode of application, the cost, &c., always +keeping in view the life of the animal to be saved and the interest of +the cattle owners. + +We think that the treatment by inoculation might have prevented the +typhus in a very large proportion, and that the curative medication +might have saved many of the infected cattle at the worst period of the +epizootia. + +Such, then, are the results which will one day be obtained, when we +shall be able to supersede the barbarous process of general +extermination, by the adoption of a rational treatment, founded at once +on science and practical experience. + + +IV. + + _Hygienic Measures to be taken against the Extension of the + Contagion--Acts and Orders concerning Sanitary Police + Regulations._ + +I have purposely neglected, in discussing the various plans of +treatment, certain measures to be adopted with the object of opposing +the spread of the contagion. The memorandum published on this subject by +the Privy Council, and drawn up by Dr. Thudichum, is so complete and so +clear, that we can find nothing better to say. I recommend its perusal +to all who possess horned cattle, and who have occasion to send them to +any distance. It is of the highest importance to follow this judicious +advice, as the general interest will constitute here the safeguard of +the pecuniary interests of each in particular. I add to this memorandum +upon hygienic measures, the consolidated and amended acts and orders +published under the head of "Sanitary Police." In this way those +interested will have beneath their eyes all which it is important for +them to know, both in a medical and legal point of view. + + MEMORANDUM _on the Principles and Practice of + Disinfection, as applicable to the present Epidemic of + Cattle Disease_. By J. L. W. THUDICHUM, M.D. + + + [Sidenote: I.--Principles of disinfection.] + + I.--PRINCIPLES OF DISINFECTION. + + [Sidenote: 1. Definition of disinfection.] + + 1. The term disinfection signifies the removal and + destruction, or destruction and subsequent removal of the + products of destruction, of all matters actually being or + containing products of disease capable of reproducing + disease in other animals. + + [Sidenote: 2. May include special purification and + deodorization.] + + 2. If the same processes and means, as used for this + purpose, are applied to the purification and deodorization + of places and things not actually infected, but capable or + suspected of being infected, then these preventive measures + are practically and properly included under the definition + of disinfection. + + [Sidenote: 3. Reproducers and primary carriers of + infection.] + + [Sidenote: Infectious parts of dead animals.] + + 3. The reproducers of the infectious matter or contagion are + all kinds of cattle of the ox tribe, which also are at + present in this country the only animals liable to its + specific effects. It is probable that the contagion adheres + with particular pertinacity to all secretions and discharges + from sick animals. For this reason, faeces or droppings, + urine, ruminated food, all secretions from the mouth, nose, + and eyes, and any sore parts of the surface of the diseased + animals must be considered as the principal and primary + carriers of the infectious matter or plague poison. It is + also probable that many parts of animals which have died + from the cattle plague, or have been killed during advanced + stages of the disease, are infectious, some because they are + primarily imbued with the contagion, others because they + have been in contact with it after the death of the animal. + Skins, hides, hair, horns, and hoofs, must therefore always + be treated with precaution. The chances of infection by + flesh, fat, cleaned guts, and blood, are perhaps more + remote, but cannot be lost sight of. + + [Sidenote: 4. Particular danger of droppings, or faeces.] + + 4. The cattle plague, although affecting every part of the + animal, shows its visible effects most extensively in the + intestinal canal. It is believed, and apparently upon good + grounds, that the intestinal discharges are the principal + agents, upon the distribution of which mainly depends the + spread of the disorder. + + [Sidenote: 5. Enumeration of infected things and places.] + + 5. It follows from the above, that all articles which have + been in contact with a diseased animal, or any of its + discharges, particularly its faeces, are capable of carrying + the infection for an indefinite time, and must be looked + upon as being actually infectious to other healthy animals. + Such are racks of wood or iron; cribs or mangers of wood, + iron, or stone; articles used for fastening animals; leather + collars and straps, ropes and chains; all harness of any + animals used for drawing, and all carts, waggons, and + carriages which they have actually been drawing; the stalls + or sheds in which animals have been standing; the whole + lengths of the gutters and drains through which their urine + has been flowing; the entire surface over which their manure + has been drawn, and all implements with which the removal + has been effected; the entire dung-heap upon which infected + manure has been put, and the fluid contents of the manure + pit, or of the special receptacle for the urine; yards or + sheds in which cattle have been kept to tread down long + straw, and the whole of such straw and manure, as also the + ground beneath them; paths and roads upon which diseased + cattle have walked or been carried; fields and meadows upon + which they have been grazing; all carts, carriages, trucks + and railway trucks in which diseased cattle have been + conveyed, and all the platforms, railings, bridges, and + boards upon which they have been moved thereto; as also all + apparatus which has been used to pen, tie, lift, haul, + lower, and fix them; the clothes, and particularly shoes and + boots, and iron-pointed sticks of drivers and their dogs; + the apparel of all cattle-herds or attendants, particularly + their shoes and boots; the shoes and boots of all persons + visiting places where diseased cattle are or have been + standing; and, in general, the clothes of all persons + visiting infected places, ships, and all parts of the + platforms, stages, stairs and bridges, hoists and cranes + used for embarking and landing the animals; markets, and all + sheds, and pens, and implements used in contact with cattle; + slaughter-houses, and all persons and implements in them + which have been employed upon sick cattle, as also sundry + parts or organs which come from sick animals killed in + slaughter-houses; knackers' yards, trucks or carts, horses, + men, and implements which have been employed in the disposal + of sick or dead animals; wells and ponds from which diseased + cattle have been drinking, or into which any portion of + their excreta has had any opportunity of flowing, directly + or indirectly; all fodder, grass, hay, straw, clover, &c., + and particularly remnants of fodder upon which diseased + cattle have been feeding; and, in general, all persons, + animals, places, buildings, and movable things which have + been in contact with matters proceeding from diseased + cattle, or with such diseased cattle themselves. To the + above-mentioned places and things any of the processes and + agents enumerated and described in the following may have + to be applied. + + + [Sidenote: II. Practice of disinfection.] + + II.--PRACTICE OF DISINFECTION. + + [Sidenote: A. Disinfection by earth.] + + [Sidenote: 1. Burying of animals, &c.] + + A. _Disinfection by Earth._ 1. _Burying._--All matters that + can be buried, so as to remain covered with a thick layer of + ground or earth are innocuous. The ground chosen for such + interment should be dry. The quickest, and cheapest, and + most certain way of disinfecting an animal dead from the + plague is to bury it entire. + + [Sidenote: 2. Burying of dung.] + + 2. The droppings, and all straw and other matters + contaminated therewith, may also be buried into ground where + they are not likely to be disturbed for a long time. The + places from which such droppings have been removed to be + cleaned and disinfected as will be described below. + + [Sidenote: 3. Infected manure and compost heaps.] + + 3. Manure heaps and the down-trodden manure of cattle yards, + if they have become infected by even a small quantity of the + droppings of a diseased animal, should be carefully shifted + to a suitable piece of ground, and there be transformed into + compost heaps. A layer of manure one or two feet in + thickness should be covered all over with six inches of dry + earth, ashes, and mineral rubbish; upon this another layer + of manure may be placed, and then again a layer of earth, + and so forth, until the whole of the manure is stacked; it + should be covered all over with a continuous layer of earth + of from six inches to one foot in thickness. If the manure + heap or yard manure cannot be shifted, it may be covered on + the spot with a layer of dry earth, after which all animals + are to be kept away from it. + + [Sidenote: 4. Removal of boil infected by soakage.] + + 4. If the floor of any shed or stable in which diseased + cattle has been standing is not constructed with special + water-tight and impenetrable material, it must be assumed to + be infected to the depth of at least six inches. This ground + should therefore be removed, together with any stones, + pavements, or wood work which may have been in contact with + it, carted to a piece of dry land and buried. Half-rotten + wood is a particularly favourable carrier of infection. + Mortar, bricks, loam, or any other lining of the sides of a + pen in which a diseased animal has been standing, should be + broken out and buried. + + [Sidenote: B. Disinfection by fire.] + + [Sidenote: 1. Burning.] + + B. _Disinfection by Fire._ 1. _Burning._--All infected + articles of a minor value, or made of incombustible + materials, can be disinfected by exposing them to a heat + which will char organic matter. To this class of articles + may be reckoned racks of wood or iron; cribs or mangers of + wood, iron or stone; leather collars and straps, ropes and + chains; dry manure, residues of fodder from which diseased + cattle have eaten; and all such small articles of little + value which can easily be replaced by new ones. Chains may + be exposed to a dull red heat; all other articles may be + heated over a fire of coal, brushwood, or straw until well + scorched. All new articles of ironware should be bought in a + galvanised state, to prevent the formation of rust, the + accumulations of which form convenient seats for infectious + matter, and for the same purpose it is desirable that iron + articles which have been disinfected by heat as above should + afterwards be either galvanised, or, at least, while hot be + treated with resin, to cover them with a durable varnish, or + should be varnished or painted. + + [Sidenote: C. Disinfection by chloride of lime. General + remarks.] + + C. _Disinfection by Chloride of Lime._--Chloride of lime, or + bleaching powder, is the most powerful, the cheapest and + most easily managed of all artificial disinfectants. It can + be had everywhere, and at any time, and in quantities + sufficient for every purpose. It should as much as possible + he applied in solution, of a strength varying somewhat with + the particular purpose for which it is to be employed; and + after it has been allowed to act upon the surface or matter + to be disinfected a reasonable time, should be washed off, + together with all products of decomposition. As chloride of + lime does not destroy only the infectious matter in a + mixture, but destroys all organic matter without + distinction, it is not applicable to large quantities of + matter, such as the manure of cattle, dung-heaps, &c., + inasmuch as twice or three times the weight of these matters + of chloride of lime would be required for their effectual + destruction and disinfection. It is further inapplicable to + all matters rich in ammonia, particularly putrid urine, as + it destroys the ammonia and evolves a large amount of gases, + some of which have a repugnant odour, and are perhaps not + quite innocuous. But for the disinfection of surfaces of + things and places no better or more suitable agent than + chloride of lime is at present known to science. + + [Sidenote: D. Special directions for disinfection of + stables, sheds, &c., trucks, and ships, &c.] + + [Sidenote: 1. Special directions.] + + [Sidenote: Washing.] + + [Sidenote: Scrubbing.] + + [Sidenote: All washing water to be disinfected.] + + D. _Special Directions for the Disinfection of Stables, + Sheds, Vans, Railway Trucks, and Cattle Ships,[V] and of + Persons and Things connected with them._--1. After such a + place has been cleaned by mechanical means, scraping, &c., + as much as possible, and all manure and dirt has been + carefully buried, the entire surface which has been + contaminated, or is likely to have been contaminated, should + be covered with a layer of chloride of lime in powder. The + powder should be worked about with a broom until equally + distributed. It is intended to disinfect the water to be + used in the washing process which is now to commence. Clean + water, from a hose in which it flows under pressure, or from + a force-pump, garden-engine, or from large watering-pots or + water-cans, or poured freely from buckets, should now be + applied to the entire surface by one person, while another + at the same time scrubs the entire surface; and particularly + all crevices, joints, and irregularities. The washing water + and chloride of lime are then to be worked down the gutters, + into the sinks, cesses, or natural watercourses. No washing + water from any infected place or thing should ever be + allowed to flow into any cesspool, urine-hold, dung-heap, + pond, sewer, or natural watercourse, without having + previously been mixed and stirred with a liberal amount of + chloride of lime. When the place has thus been scrubbed + until the water flows off clean, it is ready for effectual + disinfection. + + [Sidenote: 2. Actual disinfection.] + + [Sidenote: Solution of chloride of lime.] + + [Sidenote: How applied.] + + [Sidenote: How long to be left on.] + + 2. For this purpose a solution of chloride of lime in water, + in the proportion of one pound of the powder to one gallon + of water, is made. For the lair of one animal from six to + ten gallons of such fluid should be prepared. This fluid is + now distributed over the whole surface to be disinfected, + gradually, by squirting from a syringe, or by pumping + through a force-pump, garden-engine, or by watering from a + watering-pot or can with a finely pierced rose. All + woodwork, stones, bricks, cement, mortar, all fixtures of + whatever material, should be well wetted with the solution, + and immediately be scrubbed with a hard brush. Floor and + ceiling are also scrubbed, and the whole is left in this wet + state covered with the chloride of lime solution for at + least one hour, during which time care is taken that no + parts become dry. + + [Sidenote: 3. To be washed off after disinfection.] + + [Sidenote: Flushing.] + + [Sidenote: Precautions as to direction of clean water.] + + 3. As the chloride of lime and the products of its + decomposing action upon infectious matters may be hurtful to + cattle, these matters have to be carefully washed off by a + second and final flushing. For this too much water and too + much scrubbing cannot be employed. Care should be taken to + apply the clean water always to the highest parts, so as to + cause it to flow thence to the lower parts, and to wash away + the waste from the lower parts before applying any fresh + water to the upper parts. + + [Sidenote: 4. Care not to carry back dirt by brooms, boots, + &c.] + + 4. Care should also be taken to rinse and flush every broom + which has worked away sediment and waste from the lower + parts into and through the gutters and drains before + applying it again to the clean upper parts. Care should also + be taken that the working persons should not step from the + dirty or partially cleansed places on to the clean ones, as + this may suffice to bring infection back to the disinfected + place. + + [Sidenote: 5. Disinfection of workmen and tools.] + + 5. Lastly, all persons employed in this work, having swept + and flushed the gutters with the same care as the lairs, are + collected, together with all engines and tools which they + have used, as near as possible to the sink or place of final + egress of water from the premises, and there disinfected as + will be described. + + [Sidenote: Tools.] + + The tools, such as hooks, forks, spades, hoes, barrows, &c., + are scrubbed with the above solution of chloride of lime, + and subsequently water until clean; they are then + repeatedly wetted with the solution, and after it has had + time to disinfect the entire surfaces of them, they are + washed clean and laid up, or hung up to dry. + + [Sidenote: Workmen.] + + [Sidenote: Disinfection of boots.] + + [Sidenote: Disinfection of workpeople's bodies, hands, &c.] + + [Sidenote: Changing and disinfecting clothes.] + + [Sidenote: Burning of articles of little value.] + + The workmen, then, having finished the disinfection and + flushing of all objects and surfaces, effect their own + disinfection in the following manner:--They wash their boots + most carefully with chloride of lime and water, scraping the + soles and scrubbing the seams where the soles join the upper + leather. They wash their hands and arms, and by means of + clean rags or sponges they remove any splashes from their + clothes. After this they go indoors, remove all clothes from + head to foot, wash their bodies, and particularly their + hands, faces, hair and feet, with plenty of soap and water, + and put on fresh clothes and linen. The clothes and linen + which they have taken off should be treated as infected, set + to soak immediately in boiling water and afterwards + disinfected, or in water containing two ounces of chloride + of lime to the gallon in solution, or containing four ounces + of Condy's red permanganate of potash fluid in solution; or + the clothes and linen should be put in a copper and boiled + and subsequently washed. All articles of little value which + are much soiled should be burned on a bright fire. + + [Sidenote: E. Disinfection of live stock.] + + [Sidenote: 1. Stock may carry infection in two modes.] + + E. _Disinfection of Live Stock._--1. Live cattle may carry + infection in two ways: first, by being themselves infected + with the plague and reproducing the poison; and secondly, by + accidentally carrying the poison from other animals in a + dormant state upon some part of their surface, their hair, + and particularly their feet. These latter animals may + therefore infect others without being or becoming themselves + subjects of the plague. All persons therefore buying new + animals, should disinfect them before allowing them to enter + their premises. In a similar manner, if in a stable there + has been a case of plague, the healthy or apparently healthy + animals should all be disinfected. + + [Sidenote: 2. Mode and means of disinfecting live stock.] + + [Sidenote: Warming and refreshing drink.] + + [Sidenote: Penned in the quarantine shed.] + + 2. The mode in which live animals may be disinfected, + consists in washing them with disinfectant solutions of such + strength as will destroy the contagion without injuring the + surface of the animal. A solution of two ounces of chloride + of lime in a gallon of water, is a proper solution for + washing the coat of animals. A mixture of four ounces of + Condy's red permanganate of potash fluid, with one gallon of + water, is also a proper disinfectant solution. For + full-sized cows and bullocks, &c., several gallons of either + of these solutions should be used. Great care should be + taken to keep the solution away from the eyes, nostrils, + mouth, and tender parts. When the entire surface is washed + and disinfected, all disinfectant is removed by the + application of great quantities of clean tepid water to all + parts. The animal is given a warming and refreshing drink, + and is conducted by a clean attendant to the clean + quarantine shed. There it should receive fodder both dry and + green, and sop, and plenty of pure cold water, and be rubbed + dry with whisks of straw and hay. + + [Sidenote: F. The quarantine shed.] + + [Sidenote: 1. Objects.] + + [Sidenote: Both quarantine and surface disinfection are + required.] + + F. _The Quarantine Shed._--1. The quarantine shed is + intended to keep the new and suspected cattle separate for a + period of at least ten days, in order to afford the + security, to be obtained by observation alone, that it is + not actually infected with plague. While, therefore, + disinfection of the surface of cattle removes one kind of + danger, another, which cannot be removed, can only be kept + circumscribed or penned in, and this is done by the + quarantine shed. But the keeping of cattle in the quarantine + shed would not disinfect its surface with certainty even + during a much longer period than ten days; disinfection of + the surface therefore cannot supply the precaution of the + quarantine shed, and a rigorous quarantine cannot supply the + effect of surface disinfection. Both precautions are + necessary for perfect security, although either of them, + without the other, obviates a particular kind and a certain + amount of danger. + + [Sidenote: 2. Management of the quarantine shed.] + + 2. The quarantine shed should be situated in an isolated + part of the premises. All manure and urine from it should + flow and be carried to a particular place separate and + distinct from the common dung-heap, and be buried daily. + + [Sidenote: Cleanliness.] + + [Sidenote: Persons attending healthy stock not to attend + quarantine shed, and vice versa.] + + The utmost cleanliness should be observed in the shed. All + tools, pails, currycombs, etc., used in this shed should be + used in it exclusively and nowhere else. The person + attending the quarantine shed should not be allowed to go + into the shed where healthy stock is kept, or permitted to + approach healthy stock. No person attending healthy stock + should be permitted to approach quarantine cattle, or to go + near or into the quarantine shed. But should unfortunately + only one person be available for both duties, that person + should be allowed to approach quarantine cattle only when + clothed in the safety dress to be immediately described. + + [Sidenote: G. The safety dress.] + + [Sidenote: 1. Description.] + + G. _The Safety Dress._--1. This consists of strong + water-boots reaching up to the knees, well greased all over; + of a waterproof coat, buttoned close all the way up in + front, and closing tightly round the neck and wrists. The + head is to be covered with a cap which takes the hair well + in. + + [Sidenote: 2. Persons who should use the safety dress.] + + [Sidenote: To disinfect before leaving suspected or infected + premises.] + + 2. Every person having occasion to visit sheds in which + there is diseased cattle, or suspected cattle, or quarantine + cattle, should be provided with the above dress, put it on + when entering the place, take it off when leaving the place, + and have it disinfected immediately. This precaution should + be strictly observed by all inspectors, all veterinarians, + or others called in to attend sick cattle, by all dealers + and butchers entering sheds, yards, or meadows, for the + purpose of sale or purchase, and by all other persons coming + on the premises on business in connexion with cattle. + + [Sidenote: 3. Strangers not to enter sheds except in + disinfected safety dresses.] + + [Sidenote: Proprietors of cattle to keep safety dresses.] + + 3. The owners of stock should not allow any strangers to + enter their sheds, yards, or meadows, except in disinfected + safety-dresses; and in case this should give rise to + difficulties, they will do well to have themselves one or + two such safety-dresses at hand, and to cause all persons + whose business compels them to enter their sheds, to leave + their own boots behind, and to put on the long boots, + waterproof-coat, and special cap. Only thus can they hope to + exclude all ordinary and obvious chances of infection from + their previously healthy sheds, yards, and meadows. + + [Sidenote: H. Measures to be taken where plague has + appeared.] + + [Sidenote: Killing and burying diseased animals.] + + [Sidenote: Disinfecting the living and the stables.] + + H. _Measures to be taken on Premises where Plague has + actually appeared._--1. When the plague has actually + appeared in any shed, yard, or place, the sick animal should + at once be removed with all due precautions. It is certainly + the safest and best to pole-axe the animal at once, and to + bury it entire, and then to disinfect the particular lair as + above described, clear out the stable or shed, disinfect + the whole of it and all apparatus, also all the animals, and + only to let the animals enter the shed, &c. again, after it + is completely sweet and dry. + + [Sidenote: 2. Hospital shed.] + + [Sidenote: Situation of.] + + 2. If, however, a proprietor is desirous of keeping a sick + animal because its illness does not appear severe or fatal, + he should place it in a separate shed, which must not be the + same as or near to the quarantine shed, and be distant from + all healthy animals, and so situated that the prevailing + wind does not blow from this hospital shed towards the + healthy or quarantine shed. The water should also not flow + from this hospital shed towards the others, or the yard, or + any meadow, but should be carefully drained away and sent + off the premises by a special sink. + + [Sidenote: 3. Preventing of diffusion of faeces.] + + 3. To prevent the scattering of faeces by infected animals + (and also by suspected animals and all animals suffering + from diarrhoea), their tails should be so tied to one or + other of their horns as to protect them against being soiled + by the intestinal discharges, and to prevent them from + distributing such discharges by the ceaseless motions + peculiar to these organs. The spattering of faeces should be + prevented by a copious supply of rough straw, with some + sand, sawdust, or ashes placed behind and underneath the + animal. The straw and faeces should be dealt with as has been + described. Animals affected with plague or diarrhoea should + not be led along streets, highroads, and paths, as they + would be certain to drop infectious faeces, which would then + be distributed over the entire length of these roads by the + feet of men and animals, and the wheels of vehicles. + + [Sidenote: 4. Special management of hospital shed.] + + [Sidenote: Persons to be employed.] + + 4. The sick animals should be disinfected repeatedly; their + pens should be cleaned and disinfected repeatedly, during + the course of the illness. This should be done by persons + either guarded by the safety dress, or--and this is + safest--by such as may not come into contact with healthy + cattle, or have to enter healthy sheds. All tools, pails, + fodder, &c., to be used in the hospital shed to be kept for + that purpose only, and never to be used with healthy, or + quarantine, or only suspected cattle. + + [Sidenote: 5. Disinfection of parts of dead or killed + animals.] + + 5. If the proprietor of any dead piece of cattle, whether it + has died naturally or been killed, should decide upon + dismembering it instead of burying it entire, and upon + utilising the hide, horns, hoofs, tallow, and bones, he + should disinfect the skin, horns, and hoofs, by steeping + them for one hour in a strong solution of chloride of lime, + containing one pound of the powder in each gallon of water, + and afterwards washing them. The tallow should be thickly + powdered with chloride of lime all over, and be sent + directly to the boilers. It should not be boiled in any + vessel employed on the farm. Under all circumstances, it is + advisable to let this dismemberment of dead and fallen + cattle he performed at the knacker's yard. + + [Sidenote: 6. Flesh, &c., to be buried.] + + 6. Flesh, blood, guts, lungs, and the bones of the head of + infected animals should not be trafficked with, as they + cannot easily be disinfected. They should always be buried. + + [Sidenote: I. Disinfection of meadows, fields, roads, &c.] + + [Sidenote: 1. Meadows.] + + I. _Disinfection of Meadows, Fields, Roads, &c._--1. Meadows + infected by diseased cattle should be carefully cleaned of + all dung, by burying each dropping on the spot where it + lies, cutting out the round piece of turf with the dropping + on it, and turning it upside down. The grass on the entire + meadow should then be cut and burned. It should then be left + without any cattle for at least a month, including at least + two wet days. + + [Sidenote: 2. Of roads, &c.] + + 2. All roads, paths, streets of towns, or villages should be + carefully and frequently scavenged. All carts, vans, or + waggons used for carrying manure, should be water-tight, + caulked and painted, and should not be permitted to ooze and + drop their fluid or semi-fluid contents on the road over + which they are drawn. They should be kept clean and + disinfected, as a precautionary measure, by the proceedings + above described. + + + [Sidenote: III. General recommendations.] + + III. GENERAL RECOMMENDATIONS. + + In conclusion it must be pointed out to farmers, dairymen, + and all persons having charge of cattle, + + _That the same great measures which are known to maintain + and restore the health of human beings, will also maintain + and restore the health of cattle._ + + Pure air; dry, spacious, well-ventilated and well-drained + clean sheds; clean and dry meadows; plenty of pure water; + frequent currying and washing; the prevention of the + development, by the destruction of the germs, of internal + and external parasites, particularly entozoa; proper food in + suitable quantities, and at proper times; protection from + inclement weather; the utmost cleanliness in the removal of + manure; the storing of the manure at a great distance from + the cattle-shed, and, in addition, the most conscientious + observance of the precautionary and disinfecting measures + above described--all these measures and agents together + will secure the utmost possible health of stock and the + prosperity of the agriculturist and dairyman. But the + neglect of any one of them will make the stock liable to + become infected, and the more so the more several or all + collateral conditions of the healthy existence of animals + are neglected. The negligent man is therefore certain to + lose, to injure his neighbour by defeating his precautions, + and to damage society; but the watchful and painstaking man + will be rewarded not only by the preservation of his + property, but particularly by the consciousness that it has + been preserved by his own care and attention, and that + thereby he has also benefited the state. + + * * * * * + +This consolidates and amends the former Orders. + + (_Copy._) + + At the _Council Chamber, Whitehall_, the 22nd day of + _September_, 1865. + + By the Lords of Her Majesty's Most Honourable Privy Council. + + PRESENT. + + Lord President. + Duke of Somerset. + Earl of Clarendon. + Earl de Grey and Ripon. + Mr. Secretary Cardwell. + Mr. H. A. Bruce. + + WHEREAS by an Act passed in the session of the eleventh and + twelfth years of Her present Majesty's reign, chapter one + hundred and seven, intituled "An Act to prevent until the + 1st day of September, 1850, and to the end of the then next + session of Parliament, the spreading of contagious or + infectious disorders amongst sheep, cattle, and other + animals," and which has since been from time to time + continued by divers subsequent Acts, and lastly by an Act + passed in the session of the twenty-eighth and twenty-ninth + years of the reign of Her present Majesty, chapter one + hundred and nineteen, it is (amongst other things) enacted + that it shall be lawful for the Lords and others of Her + Majesty's Privy Council, or any two or more of them, from + time to time, to make such Orders and Regulations as to them + may seem necessary for the purpose of prohibiting or + regulating the removal to or from such parts or places as + they may designate in such Order or Orders, of sheep, + cattle, horses, swine, or other animals, or of meat, skins, + hides, horns, hoofs, or other part of any animals, or of + hay, straw, fodder, or other articles likely to propagate + infection; and also for the purpose of purifying any yard, + stable, outhouse, or other place, or any waggons, carts, + carriages, or other vehicles; and also for the purpose of + directing how any animals dying in a diseased state, or any + animals, parts of animals, or other things seized under the + provisions of the said Act, are to be disposed of; and also + for the purpose of causing notices to be given of the + appearance of any disorder among sheep, cattle, or other + animals, and to make any other Orders or Regulations for the + purpose of giving effect to the provisions of the said Act, + and again to revoke, alter, or vary any such Orders or + Regulations; and that all provisions for any of the purposes + aforesaid in any such Order or Orders contained shall have + the like force and effect as if the same had been inserted + in the said Act; and that all persons offending against the + said Act shall for each and every offence forfeit and pay + any sum not exceeding twenty pounds, or such smaller sum as + the said Lords or others of Her Majesty's Privy Council may + in any case by such Order direct:-- + + And whereas a contagious or infectious disorder now prevails + among the cattle of Great Britain, which is generally + designated the "cattle plague," and may be recognised by the + following symptoms:-- + + "Great depression of the vital powers, frequent shivering, + staggering gait, cold extremities, quick and short + breathing, drooping head, reddened eyes, with a discharge + from them, and also from the nostrils, of a mucous nature; + raw-looking places on the inner side of the lips and roof of + the mouth, diarrhoea or dysenteric purging:" + + And whereas several Orders, dated respectively the 24th of + July, the 11th, 18th, and 26th of August, 1865, have been + made under the authority of the said Acts by the Lords of + Her Majesty's Privy Council, with a view to check the + spreading of the said disorder: + + And whereas it is expedient to consolidate and amend the + said Orders: + + Now, therefore, the Lords of Her Majesty's Privy Council do + hereby, by virtue of, and in exercise of the powers given + by, the said Act, so continued as aforesaid, order as + follows:-- + + 1. This Order shall extend to all parts of Great Britain. + + 2. The said Orders dated respectively the 24th of July, the + 11th, 18th, and 26th of August, 1865, are revoked, with the + exception of so much of the said Order of the 24th of July, + 1865, as empowers the Clerk of Her Majesty's Privy Council + to appoint Inspectors within the limits of the Metropolitan + Police District, provided that such revocation shall not + affect any appointment made, or any act done, or penalty + recoverable, under any Order hereby revoked. + + 3. In this Order the word "animal" shall mean any cow, + heifer, bull, bullock, ox, calf, sheep, lamb, goat, or + swine; and the word "Inspector" shall include any Inspector + appointed under this Order, or under any of the said revoked + Orders. + + 4. Whenever the Local Authority, as hereinafter defined, + shall be satisfied of the existence of the said disorder in, + or have reason to apprehend its approach to, the district + over which his or their jurisdiction extends, it shall be + lawful for such Local Authority, if he or they shall think + fit, from time to time to appoint one or more Veterinary + Surgeon or Surgeons, or other duly qualified person or + persons, to be an Inspector or Inspectors, for the purpose + of carrying into effect the rules and regulations made by + this Order, within the district for which he or they shall + have been appointed. And the same authority may, from time + to time, revoke such appointment. + + 5. Subject to the powers herein reserved to the Clerk of Her + Majesty's Privy Council, the Local Authority within the City + of London, and the liberties thereof, shall be the Lord + Mayor; in any municipal borough in England or Wales, the + Mayor; in any Petty Sessional Division in England or Wales + (exclusive so far as relates to the jurisdiction of the + Inspector of so much of the said division as lies, within + the limits of a municipal borough for which an Inspector has + been appointed), the Justices acting in and for such Petty + Sessional Division. The Local Authority in any burgh or town + in Scotland which is subject to the jurisdiction of a + Provost or other Principal Magistrate, shall be the Provost + or such Principal Magistrate; and in any other place in + Scotland not within the jurisdiction of such Provost or + other Principal Magistrate, the Justices of the County in + Sessions assembled. + + 6. Every Inspector shall from time to time report to the + Local Authority by which he is appointed, the steps taken by + him for carrying into effect the regulations prescribed by + this Order; and the Local Authority shall certify, in such + manner as may be directed by one of Her Majesty's Principal + Secretaries of State, the number of days that such Inspector + has actually been engaged in the performance of his duty, + and the number of miles travelled by him while thus engaged. + + 7. Every Inspector shall furnish the Lords of the Council + with such information in regard to the said disorder, as + their Lordships may, from time to time, require. + + 8. Every person having in his possession, or under his + custody, any animal labouring under the said disorder, shall + forthwith give notice thereof to the Inspector of the + district within which such person resides, or if no + Inspector shall have been appointed for the district within + which such person resides, then to the Officers hereinafter + named, according to the place of residence of the person + obliged to give notice; that is to say: within the + Metropolitan Police District, to the said Clerk of the Privy + Council; within the City of London, and the liberties + thereof, to the Lord Mayor; within any other borough, burgh, + or town subject to the jurisdiction of a Mayor, Provost, or + other Principal Magistrate, to such Mayor, Provost, or other + Principal Magistrate; elsewhere in England, to the Clerk of + the Justices acting in and for the Petty Sessional Division; + and elsewhere in Scotland, to the Clerk of the Peace of the + county. + + 9. Every Inspector shalt have power to enter upon and + inspect any premises or place in which any animal or animals + may be found within the district for which he is appointed, + and to examine and inspect, whenever and wherever he may + deem it necessary, any animal within such district. + + 10. Every Inspector shall have power within his district to + seize and slaughter, or cause to be seized and slaughtered, + and to be buried, as hereinafter directed, in any convenient + place, any animal labouring under the said disorder. + + 11. Every Inspector shall have power within his district to + cause to be cleansed and disinfected, in any manner which he + may think proper, any premises in which animals labouring + under the said disorder have been, or may be, and to cause + to be disinfected, and if necessary destroyed, any fodder, + manure, or refuse matter, which he may deem likely to + propagate the said disorder. And every owner or occupier of + such premises shall obey any order given by such Inspector + for that purpose. + + 12. Every Inspector shall have power within his district to + direct that any animal which he suspects to be labouring + under the said disorder, shall be kept separate from animals + free from the said disorder. And every person having in his + possession, or under his custody, such animal, shall obey + any order given by such Inspector for that purpose. + + 13. Every person having in his possession, or under his + custody, any animal labouring under the said disorder, + shall, as far as practicable, keep such animal separate from + all other animals, and shall not, if the animal be within a + district for which an Inspector has been appointed, remove + the same from his land or premises, without the licence of + the Inspector. + + 14. No person shall send or bring to any fair or market, or + expose for sale, or send or carry by any railway, or by any + ship or vessel coastwise, or place upon, or drive along, any + highway or the sides thereof; any animal labouring under the + said disorder. + + 15. No person in any district for which an Inspector has + been appointed shall, without the licence of the Inspector, + send or bring to or from market, or remove from his land or + premises, any animal which has been in the same shed or + stable, or has been in the same herd or flock, or has been + in contact, with any animal labouring under the said + disorder. + + 16. No person shall place, or keep, any animal labouring + under the said disorder in any common or unenclosed land, + or, if the animal be in a district for which an Inspector + has been appointed, in any field or pasture, where, in the + judgment of the Inspector, such animal may be likely to + propagate the said disorder. + + 17. All animals having died of the said disorder, or having + been slaughtered on account thereof; shall be buried with + their skins, and with a sufficient quantity of quick-lime, + or other disinfectant, as soon as practicable, and shall be + covered with at least five feet of earth, or shall, in + districts for which an Inspector has been appointed, with + the consent of the owner, be otherwise disposed of; in + manner directed by the Inspector. + + 18. During the continuance of the "cattle plague" within + the said City of London, or that part of the Metropolitan + Police District which is under the jurisdiction of the + Metropolitan Board of Works, no animal shall be brought or + sent to the Metropolitan Cattle Market, or any other market + within the said City or the said part of the Metropolitan + Police District, except for the purpose of being there sold + for immediate slaughtering; and every such animal, as soon + as sold, shall be marked for slaughter, in the manner in + which cattle are ordinarily marked for slaughter in the + Metropolitan Cattle Market. + + 19. Whenever any Local Authority, as hereinbefore defined, + declares, by notice published in any newspaper circulating + within his or their jurisdiction, that it is expedient that + animals, as hereinbefore defined, or some specified + description thereof, shall be excluded from any specified + market or fair within that jurisdiction, for a time to be + specified in such notice, it is hereby ordered, that after + the publication of such notice, it shall not be lawful for + any person to bring or send such animals or description + thereof into such market or fair: provided always, that this + clause of this Order shall not, unless renewed by a further + Order, be in force after the expiration of three calendar + months from the date of this Order. + + 20. Every person offending against this Order shall, in + pursuance of the said Act, for every such offence forfeit + any sum not exceeding twenty pounds which the Justices + before whom he or she shall be convicted of such offence may + think fit to impose. + + (Signed) ARTHUR HELPS. + +FOOTNOTES: + +[R] Since these lines were put into the printer's hands, the French +Government have proposed to other nations to take measures collectively +to prevent the pilgrimage to Mecca continuing to be a cause of the +spread of cholera. We hasten to render justice to this prudent +initiative. But why not take the same measures against typhus which are +judged necessary against cholera? + +[S] The typhus which broke out fifteen days ago near Roubaix, in France, +bordering upon Belgium, where the epizootia rages, appears to have been +stifled in its focus by the instantaneous extermination of the whole +herd in which it declared itself. + +[T] "It is amusing to read authors of the last century on the treatment +of this disease. They were far more confident in their powers than we +helpless creatures pretend to be. The directions given are full and +distinct, and in chapters boldly headed 'The Cure.' The beast is to be +bled, washed, and hot vinegar and water, with aromatic herbs, may be +placed in the stable to revive the cattle. The animal must be rubbed a +quarter of an hour, both morning and evening, and the bags of a milch +cow should be anointed morning and evening with warm oil. A rowel is to +be made in the dewlap by taking a skein of hemp, tow, or twisted +packthread, a foot long, and as thick as a man's thumb. _The +prescriptions are most amusing._ They may serve to entertain those who +want the cure at present, and for this reason I reproduce one or +two."--_Gamgee, Letter on 21st August._ + +[U] Dr. Letheby reported that 12,916 lbs., or more than five tons of +meat, had been condemned in the City markets during the past week as +unfit for human food. It consisted of 64 sheep, 4 calves, 7 pigs, 142 +quarters of beef, and 361 joints and pieces of meat; 5377 lbs. were +diseased or from animals that had died of disease, and the rest was +putrid. All of it was destroyed. Yesterday, a sub-committee of the +Metropolitan Plague Committee, at a meeting at the Mansion House, passed +an unanimous resolution, on the motion of Mr. Brewster, recommending +that, as unexpected and insuperable difficulties had arisen in carrying +out the purposes for which they were appointed, the money already +subscribed should be returned to the subscribers, after deducting, _pro +rata_, the expenses already incurred. + +[V] For the disinfection of railway trucks and cattle ships, see Special +Memorandum. + + + + +THIRD PART. + +_To Farmers and Graziers._ + + +You would have had just cause to reproach me with a want of common sense +if I had obliged you to read a book of two hundred pages, and to lose +your time in looking for the advice you will require, if the cattle +plague should visit your stalls and herds, instead of being able to turn +at once to the matter which concerns you. I have taken up my pen on +purpose to be of service to you; this is my principal duty, which I am +now going to fulfil by summing up in a few pages the most important +facts which have been described in the two first parts of this work. + +The cattle plague, which has lately fallen upon horned beasts, is a +plague, no doubt: but there are different species of plagues, and it is +necessary that you should know that this disease is one arising from +the absorption of seeds and germs with which the air is impregnated, and +which is drawn by the animals into their bodies when breathing the air +around them. When these germs, these infectious poisons, have penetrated +into the lungs and blood of the animals, these seeds of infection remain +there from eight to twelve days without producing any very perceptible +effects; but after that time the tainted animal becomes dejected, loses +his appetite, is seized with fever, laborious breathing, and +diarrhoea, to which sum of disorders in the health of oxen, cows, &c., +the name of _typhus_ has been given; or, as this distemper is contagious +in the highest degree, it has also been called the _contagious typhus_. + +You may compare this disease, in order to form a more precise idea of +it, to the small-pox, which sometimes afflicts your children, or to +typhoid fever. These complaints, which are familiar to most of you, have +some resemblance to the typhus of the ox. Only in the small-pox, which +is caught by contagion, and which seldom attacks more than once, like +typhus, the disease is localized on the skin; whilst in the cattle +plague the internal organs are the principal seat of the evil. + +This comparison will show you at once that the cattle plague, or rather +the cattle typhus, can only be cured when the disease has run its full +course, as you have observed in a person tainted with small-pox; so that +your task must be to help the sick animal to endure his complaint until +the end, or until he is cured; and you must not attempt to check it by +violent means, for if you did you would hasten the death which you +desire to prevent. You will likewise understand that if the disease--as +is certainly the case--does not attack the same animal twice, it would +be very beneficial to inoculate the animal whilst he is sound and +healthy, whenever this scourge threatens--as in the present time--to +attack all cattle. Perhaps you may be told that inoculation, which +prevents small-pox in man, cannot be applicable to cattle; that animals +inoculated with the virus of the typhus have all died of the +consequences of the operation, and so on. To all these objections you +will answer, with that downright good sense which belongs to your class, +_that Nature cannot have two weights and two measures_; and that if the +inoculation of the typhus kills animals, whilst the inoculation of the +small-pox saves men, both maladies being governed by the same laws, it +is the inexperience of physicians, and not the operation itself, which +must be made to account for it. + +In a word, to sow virus is to reap it; but there are many ways of sowing +it, and one man will reap a rich harvest, whilst another shall gather +nothing but tares. Let those unbelievers say what they like, and take my +word for it, that we shall one day cure typhus as frequently as we do +small-pox, by inoculating it, and when it appears in spite of that +course, by treating it medicinally. + +This contagious disease is very frequent in certain countries, +principally in Russia and Hungary, on the banks of the great rivers +which empty themselves into the Black Sea. In those remote countries, +when the seasons are either too rainy or too hot--and you know what a +summer that of 1865 has been--the pastures generate the pestilential +poisons of the typhus, the cattle absorb these destructive principles, +and die of them. + +But as the herds of cattle in those countries are bred for sale, and are +sent for that purpose to other countries, to France, Italy, England, +&c., the animals which have had the germ of the disease transport it +with them wherever they go. Thus, it is certain that some oxen conveyed +from Russia and Hungary, where the typhus frequently rages, brought the +disease with them into Great Britain in the month of last June; and as +the complaint is communicated from one animal to another, and afterwards +at great distances, it spread with great rapidity over England and +Scotland. So great are its powers of contagion, that some of the cattle +sent back from England have transmitted the disease to Holland, in the +first place, and afterwards to Belgium; and it was feared at one time +that all Europe would be invaded by it. + +The first belief was--and everything tends to make good the +opinion--that the typhus originally came from abroad; but many +respectable authorities, seeing the foul and nauseous state of the +stalls and cowsheds both in London and elsewhere, the overcrowding of +the animals, and the general neglect to which they are exposed, have +asserted that the disease had its origin in London. This, we repeat, is +not likely to have been the case, but it is not absolutely impossible; +at all events, there can be no question that the grievous conditions in +which some of your brethren keep their cattle have contributed to spread +the distemper, independently of other causes. + +Moreover, it is necessary to tell you, that sheep and horned cattle are +of all living animals those which are most sensitive to the influence of +contagious diseases. Every year you see instances of this fact in your +own fields and meadows. Your sheep, you all know, easily contract the +small-pox, worm diseases both on the skin and in the interior of the +body; your oxen have aphthous diseases, disorders of the blood and the +lungs, scabs and carbuncles--diseases which are all more or less +contagious, and which are generally brought on by want of care, and, +above all, by improper feeding: by which you see how much of the +sufferings of the cattle, and of the heavy losses to you which follow +them, depends upon yourselves and may be avoided. Besides, these poor +creatures, which some of you treat so harshly, are extremely +susceptible, and the blows they receive may easily affect their whole +mass of blood. You must, therefore, for your own sakes, treat them more +kindly and gently. + +Therefore, the typhus which was imported from Russia into England, +finding your cattle in such wretched conditions of cleanliness and +health, was propagated amongst them with fearful rapidity. When once the +disease had developed itself within your sheds and stalls, it would have +been the wisest plan immediately to kill the sick cattle, or to treat +them medicinally, carefully abstaining from driving to market any of +your beasts which had been exposed to the contagion. But unfortunately +you did not act in this manner; many amongst you could not put up +patiently with your losses, and only consulting your private interest, +to the detriment of the general good, you sold your sick cows and oxen, +and sowing the contagion about the country and through the markets, the +scourge was soon scattered in every direction, so that instead of +stifling the disease at its birth everything was done to propagate and +diffuse it. + +Now, if we add, that the germs of this typhus penetrate everywhere, that +it is sufficient to convey sick cattle along the public roads, and by +this means to pass near farms and meadows containing healthy cattle, to +transmit the contagion, that these noxious germs impregnate your own +clothes, the fleece of sheep, and every article, implement, and vehicle +used in agriculture, you cannot but see how often, though unwillingly, +you must have disseminated the evil far and wide. + +The germs, the miasmata of the disease, insinuate themselves not only +upon animals and men, but they shed their virus upon the grass of the +fields, the walls of the stalls and stables, and every agricultural +utensil. Every tainted animal scatters the pestilential and contagious +germs, not only by the air he expires, but by his droppings, and after +death by his mortal remains--his hide, his horns, his entrails, his +flesh--all of which disseminate the deadly germs into the atmosphere, +which afterwards diffuses them in every direction. + +The germs of this virulent distemper have no doubt smitten some cattle +which appeared in the best health and conditions, those of the rich as +well as those of the poor; but, just in the same manner as the cholera +chiefly fixes itself upon the sickly, the ill-fed, the unclean, upon +those who live in crowded dwellings and badly ventilated rooms; so, too, +does the typhus choose its victims among the stalls and stables of those +graziers who keep their cows tied up for years to the rack, giving them +neither air nor exercise, and feeding them, not on that diet which their +health requires, but on those things which add to their milk and +increase their flesh. It follows, of course, that the greater number of +these cows, more or less disordered by this long course of baleful +treatment, and many of which die of consumption, after their +deteriorated milk has infused into men the seeds of diseases, must +afford an easy prey to the typhus, _to receive which they seem almost +expressly to have been trained_. + +It is highly important then, farmers and graziers, that you should be +able to recognise this ox-typhus; in the first place, that you may take +the necessary measures to prevent its contagion; and secondly, that you +may apply the treatment which shall have been recommended to you. + +You must at all times, but above all when the contagious disease is +raging, keep a watchful eye on your cattle. If you notice in their gait, +in their looks, about their ears, any unusual signs; if they seem to you +less eager, less active, less vigilant, if they leave any part of their +rations when in the stables, or if, when in the fields, they no longer +browse with that continual alacrity which sometimes it is difficult to +divert them from, be upon your guard, and dread the outbreak of the +complaint. If to these changes of minor importance is added an appetite +really less acute, if the rumination is less regular, if the animal +looks sad and dispirited, if he exhibits an unwonted look of gloom, if +his leaden eye continues fixed, astonished, be sure a morbid change is +inwardly at work, and that this cruel distemper is spreading through his +frame. + +By-and-bye the animal loses his appetite more and more; rumination is +shorter and less frequent; he holds his head down, his ears sink and +fall; he grinds his teeth. Then as to the cows: their milk, which was +already diminished, suddenly dries up altogether, and that lowness of +spirits which had been visible for some days before, passes into stupor. +If at this time you touch their horns, their extremities, their hide in +any part, you find that all these different parts are sometimes warm, +sometimes cold. From this day forward you will witness, one by one, a +succession of disorders in the animal's health: partial shiverings at +the attachment of the fore and hind limbs, loud panting breathing, with +slight cough, the urine scanty and thick, the droppings hard and +constipated, and finally, general excessive warmth. If you press the +back the pressure will be painful, and all the signs of intense fever +will be manifest. + +Already these indications have divulged the nature of the malady you +have to deal with; but others more significant succeed them which remove +every doubt. The breathing becomes more hurried and oppressed, more +puffy; from the eyes, nostrils, and mouth there issues a discharge +which, thin and irritant at first, soon becomes thick and purulent, and +of a fetid smell. Diarrhoea takes the place of constipation; the +sexual organs of the cow are red and inflamed, and furrowed with livid +streaks. The cattle grow leaner and leaner, some of them dying at this +period. If they still hold out, the diarrhoea becomes more frequent, +more fetid, and sometimes bloody; gases are developed under the skin, +along the spine, where they form wide flat tumours, which crackle when +pressed upon with the fingers. Finally, the mucus which runs from the +head becomes still thicker and more fetid; a glutinous foam stops up the +mouth; the eyes, filled with humour, sink in the orbit; the bodily +warmth decreases, the animal sways his head from right to left, becomes +insensible, cold; his head lolls on one side, and he dies, panting, from +exhaustion and asphyxia, the tenth or twelfth day after the disease has +been confirmed. + +The carcass exhibits a repulsive appearance; the hide is dry, +excoriated, and cracked; it sticks to the bones, which show the form of +a skeleton, and the putrid decomposition, which had already set in +before death, seizes rapidly on all the tissues. + +The course of the disease is not always the same. Sometimes the animal +is agitated at first, and all the functions of life are so disturbed +that death comes on in the two or three first days. At other times, the +lungs are more affected than the other internal organs; the cough is +more intense, the breath hurried and obstructed, the excess of mucus +preventing the air from passing into the chest. + +When once you have seen this disease it is impossible to mistake it for +any other, unless it be the chest complaint called peripneumonia, which +is likewise contagious. But in this disease, as the Report of the Royal +Agricultural Society states, the attack is generally insidious; the eyes +preserve their vivacity, and the appetite is not lost until towards the +close. A short, dry cough shows itself from the outbreak, and persists. +The breathing is frequent and painful; the sides of the chest when +struck with the fingers give out the hard, solid sound of a full barrel, +this percussion being painful. The eyes, nose, and mouth do not +discharge those purulent secretions seen in typhus; the diarrhoea only +comes on at the end, being less frequent and fetid. In the milch cows +the milk decreases, but is not quite suppressed. The heat of the horns +and lower extremities is retained. The peripneumonia, in a word, runs +its course more regularly, and carries off the animal about the fourth +week. Thus it will be seen that the two distempers widely differ in +their symptoms. + +Every beast which dies of the contagious typhus, bears on its digestive +organs the traces of the malady, more or less strongly marked. The third +and fourth stomachs and the intestines exhibit red or livid patches, and +at other times ulcerations. + +The cattle plague is by far the most formidable malady which can affect +animals. When left to itself, or treated without discernment, it carries +off ninety cattle out of a hundred. In prior visitations, especially +that of 1750, when six millions of horned beasts were swept off in +Europe, England lost from three to four hundred thousand; and we may +suppose that the number of cattle which have perished since last June +exceeds sixty thousand. + +_The treatment_ is very difficult, owing to the contagious character of +the disease, and it has given rise to much discussion. In some +countries, the governments, considering the distemper incurable, only +seek to stamp it out wherever it may appear. They slaughter all the sick +cattle, and even those which had come near them, allowing a compensation +of half the value of the beast. This measure has not always proved +successful, the disease having in spite of it sometimes extended over +the whole of the country thus defended from its diffusion. + +England protected by the sea, and which has been spared for a century, +was taken somewhat unawares, so that some uncertainty has been witnessed +in the measures employed to arrest its course. In some districts, the +parties interested have had the good sense to form assurance funds; and +it is much to be regretted that the same plan has not been adopted for +the metropolis. + +But we cannot help what has been done; let us, therefore, be reconciled +with the past, and see what is best to be done in future for the +interests of all. What is the present state of the matter? A certain +number of districts, both in England and Scotland, are still exempt from +the typhus; in others the disease is generally extending its ravages. + +Those districts which hitherto have been spared, should institute +assurance funds, and take every precaution to secure themselves against +this scourge. In France, in Belgium, even in Great Britain, some places +managed, in 1750, to successfully protect themselves by prohibiting the +importation of any foreign cattle or animal. These preventive measures +may now be taken with some chance of success in certain parts. Ireland, +which, thanks to the published Orders in Council, seems to have escaped +up to this time from the contagion, shows us the effectual results of +these sanitary measures. + +As for the districts already infected, it is of the highest importance +to send no more tainted beasts to the different fairs and markets, +otherwise the distemper will spread indefinitely: the unsold cattle, the +sheep, the pigs, which are placed only a few yards apart, must +necessarily convey the contagion everywhere. It would even be necessary +at this time not to collect oxen and other animals together in the same +markets; we urgently invite the attention of all public authorities to +this most important question. + +At all events, the farmers and graziers who, after all the cautions they +have received, all the orders which have been published, and all the +dangers which have been clearly exposed to them, should still persist in +driving their cattle out of their abodes, would deserve censure, and +ought to be heavily fined. The best they can do, since the contagion has +not been prevented, is to submit their cattle to the treatment which we +are now going to explain to them in detail. + +It has been abundantly proved by the many convictions at the various +police courts, that the flesh of cattle seriously diseased has been sold +to the consumers, to the great injury of the public health; and if the +cholera, which is steadily and surely advancing towards us, should mix +its fatal germs with those of the ox-typhus, we must all expect +deplorable consequences, in case the flesh of tainted oxen should +continue to be sold by the butchers, as during the last three months it +has been. + +Every farmer or grazier who shall have fully ascertained that the ox +typhus has insinuated itself into his farm or his stables, must +instantly have recourse to the necessary measures and safeguards by +means of which he may limit its pernicious influence, and prevent the +spread of the contagion to his other cattle still sound and healthy. Let +him immediately divide his stock of animals into three classes or +lots--the first class must consist of healthy cattle, having had no +direct contact with the infected beasts; the second class must contain +those cattle which, though not yet sick, may become so, because they +have been in contact with those tainted; the third class will be +composed of cattle smitten with the typhus. + +The sound and healthy cattle forming the first class must be removed +from the farm, and driven to the field separately, by some other road, +in different pastures, and only after the dispersion of the morning +mists. Those which are accustomed to continue at the rack must be taken +out twice a day, for the twofold object of taking wholesome exercise, +and allowing their stalls and sheds to be cleaned. + +Their feeding must be attended to and watched with very particular care; +the rations of those which were being fattened up must be decreased, and +they ought to be sold to the butcher for consumption as soon as +possible. Let the following provisions be added to their daily +sustenance: + + Pounded oats 4 pounds. + Pounded juniper berries 1 pound. + Powdered gentian 1 ounce. + Sulphate of iron 2 drachms. + Carbonate of soda 2 " + +The herdsman who tends the cattle whilst feeding in the fields must have +them cleaned every day: he will carefully wash and scrub them; he will +not allow them to drink out of the ponds, or at any stagnant and muddy +watercourse. + +Those belonging to the second class must receive the same strengthening +and tonic ration in the morning; and, twice every day, one of the +following anti-contagious preparations: either a solution of _chlorate +of potash_ or of _permanganate of potash_; two drachms of either of +these salts dissolved in eight ounces of warm water, mixed afterwards +with a gallon of an infusion of sage or hyssop, just at the time when +the drink is given to them. + +Or you may employ, for the same purpose, a solution of arseniate of +soda--two grains dissolved in four ounces of water, and mixed with +their drink in the same way. You need hardly be told that these doses +must be reduced one half, when you have to treat a calf or a heifer, and +that the same diminution will hold good, in their cases, for all other +medicaments. _The use of these anti-contagious drinks is of the highest +importance; I recommend you earnestly to study their effects, and to +continue them even after the distemper shall have broken out._ + +These drinks having no disagreeable taste, the cattle take to them in +general; should the contrary be the case, give them in a bottle as all +men who are cattle owners know how to do. + +If the health of any of these animals among which the outbreak of the +typhus is apprehended should seem below the standard, you must apply a +purgative to those whose bowels do not operate well, and even have +recourse to bleeding in exceptional cases. + +During the absence of those cattle which are undergoing the preventive +treatment, let the hygienic conditions of their stalls and sheds be +looked to; for no circumstance must be overlooked or neglected if we +hope to withstand the propagation of so formidable a malady. Be careful +to take out the litter every day, to wash the floor and cleanse it of +the droppings, to ventilate the place thoroughly, to fumigate it with +burnt sulphur or aromatic plants, such as juniper berries, sage, +rosemary, salted with nitrate of potash and arsenic acid; in order to +promote the combustion and give effect to its disinfectious properties. +At night, camphor or tar, or naphthaline, or creosote, or even iodine, +may be left in the stable to diffuse their vapours; all these measures +are very effectual in modifying the air. + +Let us now see what must be done with respect to the sick animals +themselves. + +The typhus, as we have said, when once it is developed in an ox or cow, +usually pursues its fatal course until the last period of its cure; +generally death alone can arrest its march. Besides, the disorders which +this disease produces in the various functions of the body are not the +same at the different stages of its duration. Thus, for instance, the +fever produces great excitement in the beginning, but later it produces +exhaustion. Without being a physician, a man can understand that the +treatment to be applied to these different states ought not to be the +same. We must, moreover, observe that the typhus is of all known +distempers the most difficult to treat. It requires in the doctor a +degree of skill, of practical experience, vigilance, decision, and +sureness of hand which no man can be expected to possess at the first +outbreak of the epizootia. + +On the other hand, the constitution of the ox, so easily shaken, +undergoes in two weeks all the commotion which a man labouring under +typhoid fever would be subject to in a month. The phenomena succeed each +other with terrific swiftness, leaving scarcely time for us to act, or +for the medicines to operate. Do not, therefore, marvel at the great +mortality among your cattle, and at my repeated recommendations of the +preventive treatment by means of inoculation. + +At the outbreak, you must reduce the violence of the fever, prevent the +derangements in connexion with the nervous centres, assuage the thirst, +empty the stomachs and intestines, which will be the principal seat of +the complaint, and sometimes let blood. + +But how are you to obtain these results? By abolishing the solid +feeding, which is easily done, since the animal has lost his appetite. +Give him to drink, three or four times a day, half a pailful of a +decoction of good hay, adding thereto a sprinkling of salt; or a +decoction of wall-wort, with a drachm of nitrate of potash; or water +whitened with bran and flour, or whey, with a little vinegar. If the +animal has a tendency to cold, if he coughs, if his breathing is +oppressed, give him warm drinks, consisting of an infusion of mallow +leaves and borage, or else a light decoction of barley and oats, and +cover the animal's body warmly over. + +Now, with respect to purgatives: give the animal, night and morning, +according to the effect produced, 6 or 8 ounces of Epsom salts (sulphate +of magnesia), or an equal dose of Glauber's salt (sulphate of soda), +dissolved in two pints of honey-coloured water; or 12 ounces of linseed +oil in some warm drink; or a decoction of senna leaves and prunes, with +an ounce of sulphate of soda added thereto. + +We might point out a larger number of purgatives, but we shall desist +from so doing. Those which we have just prescribed, not being irritant +to the intestines, are the best which can be employed. + +If the animal is very restive, if he passes through alternate fits of +dejection, stupor, and great excitement, you must have recourse to +bleeding, particularly local bleeding, by opening the small veins of the +head. If the excitement does not abate you must add, night and morning, +to one of his drinks, 2 grains of extract of belladonna, or a half ounce +of powdered belladonna leaves. If the fever, at first, is irregular, and +tends to become malignant, you must then have recourse to sulphate of +quinine, 20 grains in the morning, and the same quantity during the day. + +When the disease is principally seated in the lungs, add to one of the +pectoral drinks 4 ounces of oxymel of squills, and 2 grains of opium, +giving also an emetic--5 grains of tartar-emetic to 4 pints of water--to +be taken in four times, at intervals of two hours. + +Whilst this medication is applied to the internal organs, let the animal +have unusual care taken of him; let his head be washed several times a +day with vinegar and water. + +Such is the course of treatment to be adopted during the first three or +four days. It must be, of course, followed methodically, watching and +obeying the signs of nature. The purgatives must not be given on those +days when the sick animal is bled, and the doses must vary with the +effects they produce. + +From the fourth to the seventh day the symptoms change, diarrhoea +shows itself, and the running appears at the nose, mouth, and eyes; you +must then continue the use of purgatives, but the dose must be weaker. +Those mentioned above are suitable in every way. The drinks, too, +continue the same. Sometimes, at this period of the disease, the animal +is utterly cast down, nothing can draw him from his stupor: he lies down +the whole day; in this case you give him acetate of ammonia, from 1 to 6 +ounces, in a pint of water, gradually increasing from 1 to 2 ounces a +day, according to the effect produced; and meanwhile, plain +non-acidulated drinks should be administered. + +At this stage of the disease it is right to assist the depurative work +of nature. This is effected by inserting a seton in the neck, and the +secretion of this issue is kept up by means of such an ointment as the +basilicon with powdered cantharides. Finally, the mouth, nose, and eyes +must be washed very often with an infusion of camomile and sage. + +At the last period of the distemper, the beast sinks into a state of +general exhaustion; his life seems all but extinguished through excess +of weakness. You must now sustain and keep him up by every possible +contrivance; give him bitter and stimulating drinks, beer diluted with +water, adding thereto some powder of Peruvian bark, or sulphate of +quinine. This is prepared by steeping in 8 pints of boiling water, +Peruvian bark, gentian root, centaury leaves and flowers, and hops, 1 +ounce of each; or else prepare a drink consisting of veterinary treacle, +extract of juniper, 1 ounce of each, dissolved in 2 ounces of alcohol, +and then mixed with 3 pints of water. + +When the diarrhoea becomes fetid and bloody, give, night and morning, +a clyster composed of a decoction of Peruvian bark, and a teaspoonful of +powdered charcoal from the poplar, well sifted. If the running from the +nostrils begins to stop, you must inject into the nasal orifices some +spoonfuls of a sternutatory solution, thus composed-- + + Spanish pepper 1 ounce. + Essence of turpentine 1 " + Camphor 2 drachms. + Vinegar 2 pints. + +Should any sores form on the skin, or should they arise from the opening +of purulent deposits, dress them with the following ointment-- + + Acetate of copper 1/2 a drachm. + Calcined alum 20 grains. + Sal ammoniac 20 " + Camphor 1/2 a drachm. + Common ointment 1/2 an ounce. + +If the natural heat diminishes greatly, if the chill reaches the hams +and skin, let the beast be rubbed all over, three times a day, with +wool, moistened with the following liniment-- + + Laurel oil 1/2 an ounce. + Green soap 1/2 " + Volatile oil of lavender 1/2 a drachm. + Solution of ammonia 1/2 " + +Simultaneously with the above, give the following cordial, to be drunk +in two draughts-- + + Cinnamon 1/2 an ounce. + Extract of gentian 1 ounce. + Red wine 2 pints. + +Should the animal fall into a state of lethargy, you must have recourse +to strokes of fire, according to surgical usage. + +This distemper must extend to its extreme degree of gravity before it +advances towards its cure; you need, therefore, not despair until the +last moment. At this period of exhaustion, the drinks above-mentioned +are given up, or you add nutritive beverages to them, such as beef-tea, +fat soups, milk, and farinaceous drinks. + +If the animal holds on, and his appetite returns, which will be shown by +the desquamation of the nostrils, by the return of rumination, by the +habit of the beast to look right and left, to question you in a manner, +add cut straw to his nutritive drinks: send him out every day into the +open air, and let him return by slow degrees to his habitual feeding. +But it is extremely important to watch the intestinal functions; to +diminish and change the food, if the diarrhoea returns; as such +relapses often cause the death of an animal considered out of danger. + +Such, then, farmers and graziers, is the treatment to be opposed to the +ox typhus: it is simple as respects the remedies, and I have deemed that +it ought to be so, in order that the medicines prescribed might be had +everywhere, and at a cost which the poor man could command as well as +the rich. The disease is variable, it is not always equally deadly; and +there comes a moment when in some sort it cures itself, with a little +assistance and watching. The great point is, to be careful and vigilant, +to attend to nature and the instincts of the suffering cattle, and lend +yourselves to both. + +I cannot reproduce here the instructions given by the Privy Council to +protect your cattle from contagion, and above all not to propagate it, +but I shall refer you to Doctor Thudichum's _Memorandum_, page 257. This +exposition is too complete to need anything added to it by me; study it +well; let it be your monitor and guide; read it over again and again; +your own interests and those of the whole country depend on the manner +in which you shall treat this admirable warning. + +There are in this disease, as in every other, unforeseen varieties and +complications, such as those which are brought on by the gestation and +abortion of cows, and those proceeding from prior disease; for these +accidents you will provide. Moreover, such a terrible distemper can only +be treated according to the advice of a professional man. Call him in, +then, follow his advice and prescriptions with rigid exactness, and do +not attempt to do better than he; and, above all, arm yourselves against +the insidious pretensions of quacks and charlatans, whatever mantle they +may put on to hide their ignorance. + + + + +FOURTH PART. + + _Suggestions on the Improvements to be effected in the Study + of Medical Science, in order that we may be in a Condition + to confront Diseases generally, but Epizootic and Epidemic + Diseases in particular._ + + +The epizootia of bovine typhus which is now extending its unrestricted +ravages over this island, and which has assumed the magnitude of a +general calamity, has naturally excited and stirred up the public mind. +Thoughtful and earnest men could not look on and witness unmoved the +ever progressive march of the scourge; but each observer has, +consistently with his means and qualifications, striven to find a remedy +to resist the evil. Thus, we have seen, and with respectful interest we +have watched, the gentlemen of the press, and other men of letters, +economists, scientific men, and, above all, physicians, producing from +day to day in the newspapers articles and letters of remarkable merit +on the all-engrossing subject of this epizootia. The re-opening of the +medical colleges furnished the skilful professors at their head with a +seasonable opportunity to consider this dire distemper, according to the +views of general pathology and medical philosophy, and this they have +done with unquestionable talent and ability. Still, something remains to +be said on this important matter, and since I have taken up my pen, like +others, I wish to mingle my voice with that of my brethren, and inquire +whether the time is not come to avail ourselves more fully than we have +done yet of the grand discoveries of the exact sciences, which, with +respect to the science of medicine, are the instruments of its progress. +And my object in doing so, is, that we may, as far as possible, rise to +a level with the ordeal which the future may have in store for us. + +Medicine is at once an art and a science. An art it has been at all +times, and in every age of civilized man; but it became a science only +when human knowledge had acquired a certain expansion; when natural +phenomena had been tested and explained; when mathematics, physics, +chemistry, botany, general anatomy, general pathology, had enabled the +inquiring physician to study with important results whatever belongs to +his theme; to understand the serial chain and connexion of bodies with +each other, in the mineral, vegetable, and animal kingdoms, and to +investigate their immutable laws. Uric acid, as we see with the +microscope, will always crystallize in rhombohedrons, according to a +fixed law; the vegetable cell, the germination of a seed, must obey, and +always submit to, the innate and indestructible forces inherent in them. +That which is true in the vegetable is true in the animal world, as +regards the pre-established order which regulates and controls the +phenomena of life. These laws which govern the development of organic +phenomena being immutable and everlasting, permit the different +generations which succeed each other on our globe to build upon a +durable basis, which certifies to the slow and laborious, but +irresistible march of human progress. + +Medical science being in truth only the application of other positive +sciences to the preservation of health and the cure of diseases, +continues like them to perfect itself incessantly; but all it can do is +to follow them at a distance, and it can never hope to reach their +degree of superiority. + +These are truths which have been long admitted and felt by us. +Therefore, we have appealed for assistance to the discoveries of the +natural sciences: physics, chemistry, have in our hands become effectual +means of observation and analysis; and we, in our age, gain more +knowledge in fifty years than our forefathers did in several centuries, +for they were then necessarily rather artists than scholars. In a word, +medical science or biology is constituting itself, and if it be fully +conscious of its impotence in the case of many diseases, it also knows +its progressive improvement. It is striving to achieve the highest place +among social institutions, and the day may come when it shall obtain it, +for nations will then owe to us their health and life--that is to say, +their earthly happiness. + +The laws by which organic phenomena are regulated, are, we have said, +everlasting; we may also declare that they are general. One of these +laws common to the plant, to the shell, to every species of vertebrata, +reappears in man, whose organization comprises all the functions divided +among the other organic kingdoms. Not only does the organization of man +obey the laws which govern the vital phenomena of other animals; not +only does he possess their organs and functions, but he is a tributary +subject to their diseases. So that the knowledge of the laws affecting +the functions and diseases of those creatures which are placed below him +in the scale of animals ought to be the first foundation of all medical +study. + +These truths are too manifest to be new; they are written and professed +everywhere, and every one amongst us has received general notions of +comparative anatomy and physiology at the beginning of his course of +study. But let us admit that these notions only served to expand the +circle of our knowledge and ideas, and that we seldom or never apply +them to the practice of our art. It would have been very different had +we received at the beginning of our medical novitiate, not merely in +theory and books, but practically and experimentally, precise notions of +anatomy, physiology, and, let me add, of the _pathology of all +animals_. Let us suppose for a moment that the task had been imposed +upon us before entering upon the study of human maladies, to observe the +structure of plants and animals, to submit their tissues to +microscopical examination and chemical analysis; to study experimentally +all their functions and diseases, and acknowledge that had such been the +case, the anatomy, physiology; and pathology of man would have been far +better understood, and that most of the difficulties against which we +now contend in vain in our helplessness, might easily have been +overcome. + +Comparative anatomy and physiology are the first conditions of all +medical instruction of a serious character; there can be no doubt on the +subject, but the evidence being not perhaps so palpable with respect to +comparative pathology, it will not be useless, therefore, to enter into +fuller particulars as to this subject. + +We know not whether any one has ever sought to retrace the first origin +of our diseases in the animal kingdom, but it would undoubtedly be a +study of great scientific interest. As for us, we gladly believe that +man, created to be the sovereign lord of the earth, did not originally +receive the principle of every organic disease with which we see him +affected. It seems to us probable that he was created sound in body and +in mind, but unequal is his vital powers, and in his faculties and +talents, the social functions being various and dissimilar, and subject +to physical and moral infirmities. We think it likely that plants and +animals, from which, in course of time, man's substance is formed, have +transmitted the first causes, the germs of some organic diseases with +which they were themselves affected. We see in this transmission of +animal diseases to man, a connecting link, which appears to us to be a +condition of harmony, order, peace, and happiness among all living +beings. It seems to us that the first injunction of a legislator should +be--_love other animals like yourselves_; for if man had practised this +maxim, he would have logically applied the same to his fellow-creatures; +and no doubt, with such principles to guide them, past generations would +not have bequeathed to us the innumerable calamities we have had to +deplore. + +We think that we receive from animals some of their diseases, because +the fact is palpably evident; thus they have parasitical diseases, such +as favus, taenia, psora, trichinosis, which they transmit to us. They are +likewise smitten with small-pox, typhoid fever, and with typhus; and +under certain given conditions they may transmit them to us. They die of +consumption and cancer, and it is probable that they transfuse into us +through their milk and flesh the germs of these diseases. Finally, we +have our epidemics as they have their epizootics; and here we will limit +our instances of this reciprocation. + +It is certain that the study of these maladies in animals would have +been for us the source of precise knowledge, which, if well understood +and explained, would have often led to their preventive treatment. This +is what has occurred in the case of small-pox; it is what will one day +occur in typhoid fever, in times of epidemic, as will be the case in a +certain number of other general or local diseases. + +In truth, some complaints now looked upon as inherent to the human +species, were originally foreign to it; most parasitical diseases +belong to this class. Thus man has not the _psora_, or itch--the +disease does not properly belong to him; the parasite which engenders it +is not bred in him, it is always transmitted to him by animals. It is +the same with the taenia, or tape-worm, with the trichina, or fine +hair-worm. + +Medical science, instituted on the bases of comparative pathology, would +have made the study of diseases in the brute creation, not the +collateral, but the principal object of its inquiries. It would have +applied itself to the cure of the lower animals; and whilst learning to +cure them, it would have ensured the cure of men's diseases. + +If such be the case, can any one believe that the treatment of diathetic +and hereditary maladies would be, as they still are, insoluble problems; +and that the physician would have the misery of seeing decimated, whilst +he helplessly looks on, a large part of the population, condemned +inevitably to die of consumption and cancer? Would every man smitten +with hydrophobia be irrevocably condemned to death? Assuredly, it would +not be so. + +That the physician should have been reduced to the painful necessity of +confessing his want of means, when medicine could be nothing more than +an art, we admit; but now that science has grown up and come of age, +society has a right to challenge him to do, what in past ages could not +have been expected of him. Briefly, we think that the time is come, by +blending comparative pathology with anatomy and physiology, to construct +one of the bases of the tripod on which medical science will have to +rest. The success which has already been achieved in this direction is a +certain guarantee for those which we may hope for hereafter. + +Such is our deep conviction, and perhaps we have some title to speak out +decidedly on this point, as we have long since exemplified our precepts +by actual proofs. + +Persuaded for many years that comparative pathology afforded to +industrious men a new mine, rich in precious veins for working, we +several times endeavoured to explore this fertile field. But, +unfortunately, our means of action not being consistent with our +sanguine expectations, we were repeatedly compelled to suspend our +pursuits, until at last we found at the Ecole Veterinaire d'Alfort, the +favourable opportunity and the essential conditions of which we had so +long been in quest. + +Grieved at our helplessness to stay the ravages of pulmonary +consumption, I formed one day the resolution to study that wasteful +complaint in animals in order to discover, or at least to look for, the +required remedy. With that view, I confined in a dark, cold, and damp +cellar a number of animals to practise on: birds of different species, +rabbits, a monkey, a dog, &c. To these animals I dealt out a deficient +quantity of food. The monkey, as might have been expected, was the first +to be affected, since in our climates they all die of consumption. Next, +and for the same reason, it was the parrot's turn; then the chickens and +ducks died; after them the rabbits;--in fine, at the end of fourteen +months, the dog alone survived. All the rest had sunk under consumption, +and exhibited tubercles in different organs--in the lungs or mesentery. + +It was then necessary to have the counter-proof: to place a second set +of animals in the same conditions, to produce the disease again, and +attempt its cure. But the first experiment had been a long one, and I +was forced to relinquish the inquiry, which, moreover, was above my +means at that period. + +On another occasion, it seemed to me strange that we should be obliged +to open the bladder of patients suffering from the stone, or to subject +them to lithotrity, which has also its perils. Nature, I said to myself, +forms calculi by uniting organic elements, by crystallizing them, and by +cementing them with vesical mucus. But would it not be possible to cure +the disease by employing contrary means--dissolving the calculi in the +bladder by means of continued injections, changing the chemical agents +according to the composition of the calculus, and adding thereto the +action of a galvanic current? + +After this, I pursued my inquiry in this direction. I studied for +several months the chemical composition of calculi by examining them in +their dissolved state; and I saw that those in which the alkaline bases +prevailed, being submitted to a diluted solution of tartaric acid, which +would not injure the bladder, crumbled after a time; that the calculi +with excess of acid were also attacked by an alkaline solution; in +fine, that the calculi of oxalate of lime alone seemed to resist the +action of these chemical solutions. But it is well known that they +sometimes defy all lithotrite instruments, and compel us to have +recourse to the knife. + +These preliminary experiments over, it was necessary to come to their +application, and for that purpose to make experiments on some animals. +The canine species, omnivorous like ourselves, was chosen in preference. +Bitches were selected to be practised on; for as their urinary passages +are wider and more flexible, it enabled me to insert in the bladder +fragments of calculi already analysed, which were to serve as the nuclei +to the stones they were intended to develop. + +This second assortment of animals, penned up apart from each other, were +supplied with different modes of sustenance: some of them were put upon +a diet of meat only, others on a farinaceous diet, and a third set on a +mixed course of food. These experiments were being regularly followed +up, when an important and unforeseen event compelled me to desist at the +end of six months. The poor animals were destroyed; but all of them, as +I had anticipated, had generated calculi of various chemical +composition. + +These unfinished inquiries concerning comparative pathology, thus +interrupted in spite of myself, might, had circumstances allowed them to +reach the goal, have authorized us to undertake in man the dissolution +of stone in the bladder. And how would this have been effected? By +seizing the stone between the two ends of the catheter with the double +current, and by injecting a well-sustained series of dissolvents into +the patient, whilst lying at his ease in a recumbent posture. + +Nor is this all. They would likewise, I believe, have thrown some light +on the organic production of calculi, on the lithic diathesis, and the +particular formation of the stone; and led us, in some degree, to their +preventive treatment, which is always superior to the curative remedy. + +On a subsequent occasion, I betook myself to my task under more +favourable conditions. I undertook at Alfort, conjointly with Professor +Delafond, a course of experiments on the cutaneous diseases of animals +in relation to comparative pathology, having already, whilst walking +the hospitals, published a work on the "Entomology and Pathology of +Psora in Man," which had been printed at the expense of the Academy. + +These inquiries and examinations at Alfort were persisted in for five +years, and were considered to have led to very satisfactory results as +regards general pathology. But I have spoken of these labours in the +first part of my book. + +Pardon me, reader, and do not suppose that vanity or any desire to +parade myself has induced me to refer to these experiments. No; my only +object is to show to what results similar studies might lead, if they +were executed on a large scale and on the whole animal kingdom; if, +instead of these partial efforts made under favour, some special and +appropriate medical institution encouraged earnest experimentalists, +supplying them without stint with all necessary resources, and with the +best and completest instruments of observation. + +Will any one deny, that if medical science had been settled on this +foundation fifty years ago--that is to say, since the exact sciences +first began to provide us with the means of investigation, it would now +be so impotent? Epizootias and epidemics would not thus flout us as they +do; the cholera would no longer be an enigma, nor the ox typhus so +incurable. No! a hundred times no! Medical science would not he helpless +and impotent in our day, had our forerunners been more mindful and +provident. + +But, instead of this, the science for which we plead would have done +good work. It would have made and confirmed an infinite variety of +observations on the brute creation; it would have transmitted our +diseases to them as they transmit their diseases to us; it would have +treated and cured these diseases, and every such cure would have been a +new triumph, a new victory for mankind. + +For instance, during an outbreak of cholera, this science would have +been ready and prepared to try different experiments on men and animals; +it would first have communicated the cholera to animals, and then +submitted them to a variety of experimental treatments. This cholera, +which is not an infectious fever, with its regular and assigned periods, +like typhus, and which we are not obliged to suffer to run its course, +but which, on the contrary, is a nervous affection produced by some +poisonous miasma, the toxical effects of which first of all assail the +nervous system and then more particularly the great sympathetic; the +cramps being but the result of a reflective action--_this cholera, we +say, must be curable_, and well-advised experiments would reveal the +remedy we want for it, nor should we have to wait long for the +revelation. + +As for me, I once made a desperate attempt in this direction. It was +during the cholera of 1854. We remarked whilst dissecting subjects, as +is always the case, that the mucous membranes of the stomach and +intestines, which were in a manner paralyzed, had suffered the fluid +parts of the blood to ooze out on the surface. Hence the cause of those +vomitings, and those watery and colourless diarrhoeas which nothing +can stop, so that at a given moment the patients die, poisoned, of +course, but dying more particularly through want of circulation, the +blood being reduced to its solid parts and unable to circulate any +longer. Relying on this fact, and trusting for want of better to the +secondary effects, I strove to restore to the blood its aqueous part, +and, if possible, to re-establish the circulation. + +With this view, I went to the Hopital de la Charite, provided with all +the requisite instruments. Choleraic patients were being brought there +every hour. The experiments being new, venturesome, and _dangerous_, in +the eyes of the hospital directors, I was only suffered to operate on +the moribund. The first patient, considered to be in a state +sufficiently desperate to be given up to me, was a woman, forty-five +years old. She was literally insensible, and thoroughly cold. I +hesitated for a moment to try the operation under conditions so +unreasonable, so preposterous--almost upon a corpse. The radial arteries +in the arm had ceased to beat, and the heart alone kept up a feeble +circulation at the central parts. At length I opened the vein, from +which not a single drop of blood proceeded, and taking the usual +measures to prevent the air from having access, I gradually and slowly +injected two ounces of alkaline solution, the process of injection +lasting twelve minutes. It was scarcely over before the patient +half-opened her eyelids, and looked about her with astonishment; the +pulse became perceptible for a few moments, and all present thought she +was saved. We put a few questions to her; the patient could not answer +us, but she nodded as much as to say "yes," when asked if she felt +better. But this was all we could do in her case. The circulation +stopped again, the patient relapsed into her state of insensibility and +died two hours after the injection. + +The result obtained in this instance had not answered our expectation. +However, the circulation had for a minute or two resumed its course, and +a flash of reason had once more shown itself. + +I thought the experiment ought to be repeated, and accordingly the next +morning I made another trial. The patient this time was a working +shoemaker, thirty-eight years of age, exactly in the same far-gone, +hopeless state as the patient of the day before. In his case, the inward +commotion caused by the injection was more powerful; twenty minutes +after the injection he was able to see, to understand, to speak, to +raise his head; but this vital recovery was, as in the former case, but +of short continuance, and two hours and a half after the operation the +man expired. + +After these experiments I dissected the two bodies, and then, finding +that their lungs were infiltrated with water, I understood that the +alkaline solution had not been assimilated, that it had stopped in its +passage into the pulmonary parenchyma, to the detriment of the functions +of the haematosis. I also understood that the proper injection, instead +of distilled alkaline water, would have been the serum of the blood, +drawn at the very moment from some man or animal. + +The conclusion which I drew from these experiments was that a variety of +operations, made at different stages of the malady, might lead to +beneficial results, especially if we succeeded in transmitting the +cholera to animals, as that would enable us to test a large number of +curative agents and to pursue a methodical course of experimentalization. + +From all I have said, I infer that life, health, and disease, being +subject to the same laws throughout the whole animal kind, it is certain +that the physician should possess precise knowledge as to the +organization, the functions, and diseases of animals. That by proceeding +in this manner, we shall advance from the simple to the complex, from +the plant to the animal, and from the animal to man. That we must of +necessity emerge from the state in which we are now entangled BY FOUNDING +AND ESTABLISHING IN LONDON A COLLEGE OF THE NATURAL AND MEDICAL SCIENCES. +Every medical pupil might spend two years in this college, receiving in +it an experimental and practical training; he would devote himself in it +to the chemical analysis of all bodies, to physiological experiments and +tests, without limit and of every kind. + +Most deeply do I appreciate the many difficulties and obstacles that +would interfere with the execution of such a design. In our civilized +age, nations seem rather bent on seeking out the means of exterminating +each other than of protecting themselves and animals from epidemics and +epizootias. It is believed that every first-rate kingdom now spends from +400 to 500 millions of francs (16 to 20,000,000_l._) annually in +maintaining their land and sea forces, whilst one-half of their +populations are living in misery and ignorance, in disease and +corruption. The time is not come--shall we ever see it?--to employ the +vital powers of the peoples, to better incessantly their social +condition. Perhaps, by reason of its organization, the Government of +this country would not be authorized to devote 100,000_l._ or +200,000_l._ to the establishment of an institution like the medical +college I suggest, notwithstanding its paramount necessity. But England +is in the habit of doing great things independently of the Government. +In default of the ruling powers, then, let me appeal to the national +initiative, for if the spectacle which we are at present witnessing was +not, in the case of England, one of those trials which invigorate a +people by the salutary teachings which they bring; if it did not induce +them to take some energetic resolution by which their interests would be +saved and their power enlarged, it would indeed be a deplorable sign of +the times and make us despair of its future. + +Moreover, to show the urgency of founding a _College of Natural and +Medical Science_, let us add, that in every other country they are +endeavouring to unite this indispensable complement to medical +education. The German universities, the Faculty of Paris, have, for +several years past, incorporated a course of comparative pathology, with +the other series of public lectures. + +It is not a mere Utopia that we propose, but an extension and +improvement, all the parts of which are already prepared. If this +College could be thrown open to-morrow, competent professors would be +ready at the call of duty to indite the programme for this instruction +within twenty-four hours; and as for the professors themselves, there +would be enough to choose among the large body of efficient scholars who +do honour to the country. + +If we have been rightly understood, we desire to see established in +London an institution which would afford an equivalent to what exists in +Paris, at the Museum and College de France, where numerous courses of +lectures on anatomy, physiology, physics, and chemistry are given. Only +in London this special college would be formed and organized on such a +scale as to bear away the palm from every previous foundation of the +same kind; it would be an institution unexampled in the world, out of +whose halls would one day come anatomists, physiologists, and +pathologists of the very highest order of excellence.--But organic +matter would not be the sole object of this instruction, for the animal +is something more than matter. Courses of medical history and +philosophy, of really general pathology, would introduce the students to +the grand phenomena of nature, to the great laws which govern the worlds +and the globe; and descending from the heights of science to the +observation of the infinitely minute, they would never forget the +important part of the vital powers, and of that unknown power called at +different times by the names of +pneuma+, _archec_--_mind_ and _soul_. + +The Regent's Park would, we think, be the proper site for this college, +as the contiguity of the Zoological Gardens would afford continual +opportunities for investigating the diseases of animals. + +Moreover, this college would not trench upon or interfere in any manner +with those medical and veterinary establishments which at present exist; +it would ally itself with, and complete them, nothing more. The +instruction received at this "College of Natural and Medical Science" +would be so useful and necessary, and so attractive withal, that the +sons of the great families would come to it to finish their collegiate +studies, to the great benefit of the country. Other young men, in +considerable numbers, would flock to it from various parts of the world. +The foundation of such an institution would be an epoch in the history +of science, and would give England another claim to the esteem of +nations. + +I conclude, then, with a conviction that a nation which owes to Lord +Bacon, the founder of experimental philosophy, his imperishable book on +the _restoration, the method and teaching of the sciences_; to Harvey, +the circulation; to Priestley, the constitution of chemistry; to +Sydenham, the modern Hippocrates, his treatise on "Practical Medicine"; +to Jenner, vaccination; and to Charles Bell, the discovery of the +sensitive and motor nerves--is a people too great and too enlightened to +retrograde; and that, if the epizootic of ox typhus did find them at +first unready and disarmed, they will in the end convert this disaster +into a new source of greatness and strength. + +Such is the sincere hope which I cherish and the prayer I offer up for +the happiness of a country which, for the future, has become my own. + + + + +APPENDIX. + + +NOTE A. + + BREMEN, August 30. + +The following report, drawn up by two German veterinary surgeons, of a +recent visit to London to examine into the cattle murrain, has been +furnished by the agent of the North German Lloyd's at Nordenhamm:-- + +"On Wednesday, the 9th instant, we, the undersigned, were requested to +be at Nordenhamm, if possible, the following morning. Upon our arrival +we were asked by the agent of the North German Lloyd's, who had +consulted with several of the chief cattle exporters, to undertake a +voyage to London at once in the steamer _Schwan_, in the interest of the +cattle export from the Weser. The object of our mission was, first, to +examine as closely as possible into the epidemic cattle disease raging +in and around London for some time past; then carefully to observe the +treatment of cattle upon the vessel during the voyage, upon arrival, and +at the time of disembarkation; lastly, to use every means in our power +to prevent obstacles being opposed to the continued export of cattle +from these ports to England. + +"Furnished by the agent of the North German Lloyd's with letters of +introduction to cattle dealers in London, and with the necessary funds, +we left Nordenhamm in the steamer _Schwan_, Captain Christensen, at 4 +P.M., on the 10th instant. The vessel carried 347 head of large +cattle, 2 calves, and 260 sheep. Favoured by very fine weather, we +arrived in the Thames at 2 P.M., on the 12th. At the beginning +of the voyage the animals were rather uneasy, trampled a good deal, and +caused considerable motion in the ship; after a time, however, they +became quiet. A sharp, penetrating smell was easily perceptible in the +'tween decks of the ship, which was quickly removed upon a light breeze +springing up, by means of the excellent ventilation and numerous +air-pipes and wind shafts. The animals were several times watered, and +it was easy to see how greatly they were refreshed. The hay in the +racks, on the other hand, was hardly touched. + +"Upon arriving in the port we were introduced by the captain to the two +veterinary surgeons stationed here to inspect the cattle, and witnessed +the rapid disembarkation of the cargo, all of which were thoroughly +healthy, not one being condemned. The cattle, when landed, were +immediately brought to carts standing in readiness and transported to +London, where they are cleansed and then driven into the adjacent +fields. + +"After doing all in our power to attain the object of our journey, we +went back to the port to wait for the _Schwan_, having first thoroughly +cleansed the clothes we had worn during our inspection of the diseased +cattle. The _Schwan_ came in shortly after our arrival, and disembarked +256 head of large cattle, 12 calves and 400 sheep, all in good +condition. Mr. Philipps, the London agent of the North German Lloyd's, +was on the spot, together with several reporters from newspapers, who +wished to see by personal investigation how and in what condition cattle +are brought from the Weser. + +"We re-embarked on the _Schwan_ upon the 19th. The crew were engaged +during the voyage in carefully cleansing the ship. The weather was fine, +and we arrived safely at Nordenhamm upon the 21st. + + (Signed) + + "G. J. RIPPEN, + "Veterinary Surgeon at Seefield. + + "H. FASTING, + "Veterinary Surgeon at Schwey." + + +NOTE B. + +Professor Simonds having had such opportunities of investigating those +diseases as they existed in England and in foreign countries as were +possessed only by a few Englishmen, might be permitted to offer a few +observations. He had been appointed by the Royal Agricultural Societies +of England and Ireland to proceed to the Continent in 1857, when there +was a rumour that the disease which existed among cattle in this country +at the present time was prevailing in Mecklenburg. Consuls sent +despatches that the rinderpest was prevailing largely, and the +Government, as a precautionary measure, closed the ports against the +introduction of cattle from the Baltic to this country. He found, +however, from his observations abroad that since 1817 there had been no +disease of this kind westward of a line between Revel in the Baltic and +the Gulf of Venice, but to the eastward of that line it had existed. He +came up with the affection at the Carpathian mountains, where it was +raging in 1857 just as it is raging in England at the present time. Not +only had it existed there, but it had been carried into the interior of +Russia in the ordinary method of the cattle trade. A person who was in +the habit of purchasing cattle attended a fair and bought a number of +animals, and took them to his own farm, and in the course of ten days +one or two were seized with the disease, and the result was there was a +gradual spread of the evil in that district. It gained ground until the +Government instituted the sanitary police regulations, which, though +they were such as would be considered strange in England, were, he +believed, absolutely necessary for the extirpation of the plague. It was +undoubtedly true that no foreign animals had been seized at our ports or +in the metropolitan market; but it was not necessary for the case they +had in hand to say whether the disease was or was not of foreign +importation. There was this fact before them, that it was not until the +month of June that the disease appeared in England. A certain number of +animals came out of a diseased district. He had documentary evidence +that animals came from Revel and came from the district of Esthonia. He +had before him proof that the disease now in England was raging in that +district. They had proof that shortly after the arrival of those cattle +in England the disease manifested itself here. He admitted there were +difficulties in the way of checking the importation of foreign cattle. +The Government had its eyes open to the matter, and he did not think it +possible for the Government to have done more than they had done or to +have done more quickly what they had been doing. At this moment half the +supply of the metropolitan market came from foreign countries, and he +did not wish to convey any reflection by saying that this disease had +its origin from abroad. He would admit that the animals from Germany and +Hungary were coming in a healthy condition; but he could not admit that +they came from Russia, Poland, or Galicia in so perfect a condition, +because the regulations there were not sufficient to stamp out the +disease. The Government had made an inquiry as to the general health of +cattle on the Continent. They believed France, Belgium, Holland, +Schleswig-Holstein, Oldenburg, and a large part of the Continent that +supplied cattle to this country were free from disease. This went to +show that we had admitted a disease not from where we received our +supplies of meat, but from some other district. Then it must be +associated with the fact that it came into this country when animals +arrived here from an infected district in Russia. Animals from Germany +and Hungary were often shipped and mixed with others from a diseased +district. As regarded the disease being spontaneous, we had been free +from it for twenty years. What was the state of our cowsheds fifty years +ago? Were they not in a more filthy condition than they are now? If, +therefore, the disease had been induced from common causes it would have +been here years and years ago. It was no reflection to say that a great +many cases could be traced directly to the metropolitan market. Take one +case which occurred in Sussex. Certain cattle had been bought in the +metropolitan market and were taken home. In three or four days they were +ill, and presented symptoms of this affection. In a few days more the +cows and calves were dead. In another instance calves were bought in +Chichester Market, where they had been taken from London. The result was +the death of twelve cows and ten calves. The people had other cattle on +the same farm, and not one of them took it. He could say, too, that +persons who had only one animal had lost it by the disease. How had the +disease got into Norfolk and Kent but by the animals which went from the +metropolitan market? He could prove by documentary evidence that it was +so. He could show there was not a single instance where the origin of +the disease could not be traced to the metropolis. It was the most +fearful visitation that had ever been seen in England. They had adopted +a system of compensation in Norfolk, and if by this meeting something +was done to shut out the animals of infected districts, no doubt the +promoters would receive not only the thanks of London, but the country +generally. + +Mr. Gibbins--Now, if the disease came from abroad, and diseased cattle +were shipped on the other side of the sea, no doubt the voyage would +concentrate and aggravate the disease. The Government inspectors +reported, however, that not one instance had been seen of foreign cattle +so diseased, nor had any been seized and destroyed in London or anywhere +else. Whether the disease came from abroad or elsewhere he was not able +to state. Sir George Grey asked him whether he had found any disease +among the foreign cattle that came into the market. He said not one. +They had, no doubt, many instances of the disease amongst the cows that +were ordinarily called milch cows, but that were not milch cows when +they came to market, because one effect of the disease was to deprive +the animal of milk. These were then sent to the market and sold as fat +stock. He could only say they had had no cases, except in cows, whether +they came from the dairies in London or elsewhere. + + +NOTE C. + +M. Dembinski, Professor of Analytical Chemistry and Natural Science, had +also addressed a communication to the Lord Mayor on the subject. The +prevalent Rinderpest, he said, originated in the steppes of Podolia, +from which considerable herds of cattle were exported through the +steppes to Moscow, St. Petersburg, Riga, and Revel, and thence to the +ports of Memel, Koenigsberg, Dantzic, Hamburg, Kiel, and the Hague. +_Deprived of congenial food and pure water on their transport through +the steppes, and then arriving at marshy lands, the exhausted animals +drank the stagnant water, which, during hot weather, exhaled a +pestiferous malaria, and infected them with a predisposition to the +epidemic in question, which developed itself into a kind of fever on the +voyage to England in a crowded condition._ + + +NOTE D. + + INTERNATIONAL VETERINARY CONGRESS, VIENNA, + August, 1865. + +With regard to the cattle plague, it may be well to state that Austria +has been most unfortunately situated, from the readiness with which +Russian cattle have been admitted into the country at various parts of +the western and southern frontiers. At the opening of the Congress this +difficulty was particularly noted by the Ministerial counsellor, Dr. +Vell, who attended on behalf of the Government, for the purpose of +welcoming the assembly, and giving an assurance that its deliberations +would meet with all the attention they deserved. He specially referred +to the fact that the laws relating to cattle disease prevention had been +entirely revised in 1850, but that the Steppe murrain continued to be +introduced by smuggled stock into the western and southern provinces of +the State. It was therefore necessary to attempt a more effectual +control over the propagation of so disastrous a malady. + +Herr Pabst welcomed the meeting on behalf of the Minister of Trade. He +said that the value of the cattle of the Austrian dominions considerably +exceeded one hundred million pounds sterling (one thousand million +Austrian florins), and that cattle plagues completely put a stop to the +development of that essential branch of agriculture which embraces the +improvement and increase of live stock in a country. He assured the +assembly that all would be done that was possible to improve the +existing state of matters, and that he hoped they would greatly aid the +Government by the discussions which would take place and the conclusions +at which they would arrive. + +I may state, by the way, that an opinion rather generally expressed by +some, and stoutly maintained by others, was that the peculiar +disposition of some of the Austrian subjects, and the feeling existing +in Hungary against State measures, rendered the law, to a great extent, +inoperative. I can, from personal experience, state that although +stringent and most efficient means are used for the suppression of +cattle plagues, and with the best results in Austria proper, there is +great difficulty in carrying out the law in districts where Austrian +rule is at a discount. Indeed this is clearly indicated by the manner in +which the Rinderpest penetrates into Austria, where the laws are similar +to those in the kingdom of Prussia, which is, and has long been, +completely protected from invasions of the disorder. + +At the meeting of the first International Congress, held in Hamburg in +1865, Dr. Roell stated that owing to the length of time to which the +quarantine for Russian cattle extended on the Austrian frontier, herds +of cattle were often smuggled through, and companies had been formed for +the purpose of insurance against seizure by the authorities. The +unlawful traffic was therefore carried on with comparative safety to the +dealers, who cared not what misfortune they brought on a country if only +their personal ends could be served. This question was the first to +occupy the attention of the Congress last week; when a resolution was +proposed to shorten the period of quarantine for cattle from Russia +into any country from twenty-one days to ten. The discussion was keen. +It was stipulated, however, that the quarantine should be carried out +most strictly over all parts of the frontier, without respect to any +breed of cattle or other circumstances which might be brought forward as +exceptional reasons for retaining animals in quarantine. The committee +appointed to prepare a succinct report on the subject included +Professors Unterberger, Seifmann, Werner, Zlamal, Hertwig, Haubner, and +Roell; and the committee decided in favour of the shortened quarantine, +on the following conditions:--First--When the establishment of +quarantine institutions is effected in accordance with the requirements +of trade and the peculiarities of the frontier, special attention must +be paid to the erection of quarantine stables, &c., where there are +facilities for procuring an abundance of fodder and water. Second--The +animals to be kept under efficient veterinary supervision wherever they +have to submit to quarantine. The inspectors must be properly qualified +veterinary surgeons. Third--The use of a brand to indicate that the +animals have been in quarantine. Fourth--The effectual disinfection, by +washing and otherwise, of animals as they leave the quarantine. +Fifth--The introduction of a poll-tax along the eastern frontiers, and +the appointment of proper veterinarians to be on the watch as to the +health of cattle along the frontiers. Sixth--Careful supervision to be +placed over the traffic in cattle wherever it takes place in a country. +Seventh--The punishment to the full extent that the law allows of all +who break the rules relating to quarantine or other means for the +prevention of the cattle plague. + +Professor Hertwig, of Berlin, whose opinion is always listened to with +great respect in veterinary circles, stated his reasons for adopting +these resolutions now, whereas in 1863 he was against shortening the +period of quarantine. He referred chiefly to the importance of not +offering temptations for cattle dealers to evade the law by insisting on +unreasonable restrictions. The feeling of the assembly was greatly in +favour of avoiding vexatious and expensive measures, which might greatly +interfere with the employment of capital in cattle traffic. A small +number of professors, not exceeding eight or nine, held out for a +quarantine of twenty-one days. + +It may be as well to state that quarantine regulations, which have been +regarded as almost useless in the prevention of human disorders, from +the great difficulties in the way of carrying them out efficiently, are +recognised as of great value in controlling the propagation of cattle +plagues. It is possible to control the movement of herds, and the +governments of Central Europe have found it absolutely essential so to +do. Indeed, the ablest medical men who have written against the adoption +of a quarantine system for human small-pox and cholera, such as +Professor Siegmund, of Berlin, acknowledge its value and absolute +requirement with regard to the Rinderpest. A professor from Galicia +argued in favour of controlling the movements of people wherever the +disease appeared, and no fact seems to have been better ascertained than +that of the communication of the Rinderpest from herd to herd by human +beings. Professor Jessen, of Dorpat, states that in Russia the malady +was at one time speedily propagated by the people, who regarded the +destruction of their stock as a visitation of Providence, and who +summoned a priest into their stables to pray with them that the plague +might be stayed. Moving from farm to farm, the malady was by this means +rapidly transmitted. In Hungary, many outbreaks result from people +dressing the carcases and hawking about the meat, which, even where +human beings remain uninjured, is deadly to the cattle whenever the +water with which it is washed is thrown about the yards, or the meat is +hung up near sheds containing living animals. + +The members present at the International Congress spoke in favour of +establishing a fund, apart from the Government grants, for the payment +of diseased or infected animals which have to be slaughtered with a view +to the prevention of the plague. Special precautions were suggested as +to the transmission of articles the product of diseased animals. + +1. Perfectly dried skins, the points of horns cut off, as they often are +for commercial purposes, the salted and dried intestines of cattle, +melted tallow, wools, cowhair, &.c., could be freely allowed to pass +unobserved. + +2. Entire horns, hoofs, &c., which are detached from the soft parts, but +which often contain adhering flesh, &c., should be disinfected with +chloride of lime. + +3. As melted tallow is often conveyed in bags which may be charged with +the poison, those bags should be washed with chloride of lime solution. + +4. Fresh bones, fresh skins, and intestines, unmelted tallow, raw flesh, +and fresh sheepskins, should not be sold whenever the Rinderpest exists +in a district. + +According to all the accounts which reach us, the foreign observations +and resolutions may be of essential service in England. The members of +the Assembly were informed by Mr. Erner of the origin and the progress +of the cattle plague in England, and were deeply interested by the +account given of the imminent danger in which many countries are placed +that purchase breeding stock in the British isles. The theories of +spontaneous origin amuse the learned here not a little, as they justly +think we ought not to be so far behind every nation in the possession of +knowledge regarding the propagation of such a disorder as the steppe +murrain. + + +NOTE E. + +Now, if the disease came from abroad, and diseased cattle were shipped +on the other side of the sea, no doubt the voyage would concentrate and +aggravate the disease. Whether the disease came from abroad or elsewhere +he was not able to state. Sir George Grey asked him whether he had found +any disease among the foreign cattle that came into the market. He had +not one. He could only say they had had no cases, except in cows, +whether they came from the dairies in London or elsewhere. So far as +they knew, not one single bullock or ox had been condemned.--MR. GIBBINS, +_18th August, Meeting at the Mansion House_. + +The very first shed in which the plague must have appeared in London is +a pattern of cleanliness, and the stock was magnificent, as proved by +the animals in a shed to which the disease has not been propagated. +Almost simultaneously the malady broke out in the Essex marshes, and in +every instance we trace a more or less direct contamination by foreign +stock. + + +NOTE F. + + VIENNA, August, 1865. + +On the 28th of August about thirty of the members of the Congress +accepted an invitation to visit the renowned agricultural establishment +at Altenburg, in Hungary. After the visitors had inspected the herds and +other appurtenances of this institution, Professor Maasch, its director, +intimated that the Rinderpest had appeared at Nickolsdorf, about four +German miles from Altenburg. The President of the Congress had known +this fact before the party left Vienna for Hungary; but as he feared +some enthusiasts would first see the plague, and then inspect the +Altenburg herds, he preferred to adopt the stratagem of communicating +the information through Professor Maasch, after the great Agricultural +College of Hungary had been viewed. Nickolsdorf, where the steppe +murrain appeared on the 10th of August, is an exquisitely clean village, +with well-whitewashed buildings and broad roads, constituting the centre +of a thriving agricultural district. Its people are typical Hungarians, +not too anxious to work, and, on the whole, poor; but they are +intelligent, notwithstanding the national proclivity to farm a thousand +acres badly rather than one-fourth the quantity to perfection. Their +wants are not great, and their worldly luxuries, beyond potatoes and +schnaps, are bought with the profits made on large herds of cattle. One +herd only had suffered from the cattle plague when we visited the +village. This herd consisted of 1225 animals, divided into three lots. +The affected portion numbered 450 animals--bullocks intended for work +and slaughter--varying in age from three to seven years. The cows and +heifers had not been smitten. The 450 animals amongst which the disease +appeared were housed in no less than sixteen different sheds in +Nickolsdorf. Out of each of these places sick animals had been taken, +and either slaughtered or permitted to die. We killed four for +dissection on the 29th. Six more had been previously killed, their hides +slacked, and the entire body buried; nine had died, and two we left in +life to be soon slaughtered and disposed of as the others. The district +veterinary surgeon in constant attendance was an extremely active and +intelligent man, who recognised the disease on its first outbreak, and +adopted such measures for separation, destruction, and burial, as +prevented the disease from spreading so rapidly as it has in England. + +The cause of the outbreak was the intermingling of cattle-dealers' stock +with the Nickolsdorf herd; and although the animals which carried it +have not been fully traced, they are believed to have been owned by a +butcher who had purchased them in Comorn, where the malady is raging. +Singular variations have been seen in the symptoms exhibited, especially +when animals are first affected. During the Nickolsdorf outbreak there +has been an invariable incubation of five or six days; then furor or +delirium appears: the bullocks stare, roar, stamp with their feet, are +prepared to attack people who approach them, and seem to be dizzy at +intervals. They shiver, their muscles twitch, the eyes soon begin to +discharge, and the mucus which flows from the mouth foams. The pulse is +at first slower than usual, until all the fever symptoms appear. There +is more constipation than diarrhoea, though, on examination, the +mucous membranes are all found to be affected precisely in the manner so +often observed in England during the present outbreak. The differences +in the symptoms are accounted for by peculiarities of breed, the +condition of stalls, the food the animals have lived on, and similar +circumstances. We may hear more of these Hungarian outbreaks, but the +chances are we shall not witness in any part of Austria the wholesale +devastation now going on in Great Britain.--_International Veterinary +Congress._ + + +NOTE G. + +At present the cowkeepers send off the infected beasts to the market, or +to some slaughter-house, where they might be killed. There was believed +to be great danger in allowing the infected cows to be driven through +the streets. If the good could be separated from the bad animals, and if +the latter could be conveyed to sanitoriums, where the medical men could +operate upon them, then much benefit would result; and then, too, if the +animals died, they would be buried on the spot. All the professors were +agreed in this, that if a compensation fund were raised, and the +cowkeeper were told that he would be remunerated for his loss, he would +at once inform the authorities when the disease made its appearance in +his cowshed. Shed after shed was being now shut up, and men and women +who seemed to be affluent one day were the next reduced to ruin. An +illustration of this would suffice. One day last week a cowkeeper at +Pimlico had 70 or 80 healthy cows. On Wednesday three of them were found +dead. On Thursday 42 of them were sent to the market. Of these 42 three +showed symptoms of the disease, and then the whole of the 42 beasts had +to be slaughtered because of the disease being among the three. The poor +fellow was thus ruined. Last Monday he sent nine more cows to the +market, and these also had to be slaughtered. At present the man was +absolutely out of his mind. Out of his 70 beasts, he had not one left. +Some persons were saying that the disease arose from bad water, bad +ventilation, and bad cowsheds; but in the case of Miss Burdett Coutts, +who had had 40 head of cattle, which were most carefully housed and +attended to--particularly from the moment she heard that the disease was +amongst them--all were gone, with the exception of one cow; so that, +whether it was a want of water or a want of ventilation which in other +cases caused it, this was an instance in which everything was done that +could be done, and yet the plague raged and the mortality +ensued.--MR. GIBBINS, _Meeting at the Mansion House_. + + +NOTE J. + +Yesterday morning Dr. Jarvis, medical officer of St. Matthew's, +Bethnal-green, received information that Mr. Castell, an extensive +purveyor of milk, had lost eighty-four cows during the past week. Other +cowkeepers in this district have also experienced great losses. The +disease has manifested itself with more or less virulence at St. Anne's, +Limehouse; St. John, Hackney: St. Mary-le-Bow, St. George's-in-the-East, +St. John, Wapping; Christ Church, Spitalfields; St. Leonard's, +Shoreditch; St. Mary, Whitechapel; St. Paul's, Shadwell; the hamlet of +Ratcliff, Stoke Newington, Kingsland, and Tottenham. + +Mr. Gibbins, chairman of the Metropolitan Markets Committee, Mr. Rudkin, +a member of the committee, Mr. Tegg, veterinary surgeon to the market, +and Mr. Baldry, clerk to the market, applied to the sitting magistrate +at Clerkenwell Police Court yesterday for summonses against cowkeepers +for sending diseased cows into the market. During the course of the +present week no less than nineteen cows had been seized in the market +and fairs and condemned. The order was asked for under the 8th section +of the recent Order in Council, which recited that it shall not be +lawful to send or bring to any fair or market, or to send or carry by +any railway, or by any ship or vessel coastwise, or to place upon or to +drive along any highway, or the sides thereof, any animal labouring +under disease. The cattle seized had not been examined by a Government +inspector, and no certificate had been given to the owners that they +were fit to be removed. The market authorities wished it to be known +that proceedings would be taken in every case that was brought under +their notice. Mr. Cooke observed that the inspectors had power to seize +and slaughter, or cause to be slaughtered, and to be buried in any +convenient place, any animal labouring under the disease. Had that been +done? Mr. Tegg said that the animals were in some of the cases +slaughtered, and the others would be slaughtered in the course of the +day. The summonses were granted. + +Yesterday, the summonses issued at the instance of Mr. Frederick Thomas +Stanley, a member of the Royal College of Veterinary Surgeons, and one +of the inspectors appointed under the Order in Council, came on for +hearing before Mr. Burcham, magistrate at the Southwark police court. +The summons in the first case was addressed to Thomas Meredith, of the +Flying Horse-yard, Blackman-street, for that the defendant, without the +licence of the said inspector, did unlawfully remove from his premises +some animals labouring under the cattle disease. Mr. Sleigh, instructed +by Mr. Gant, appeared to support the summons; and Mr. W. Edwin for the +defendant. Evidence was given that the defendant had been warned that +the cows were diseased, but that he had removed them notwithstanding. +The further hearing of the case was adjourned, as were also the other +summonses of a like nature. + +In pursuance of powers vested in him by the Manx Legislature, the +governor of the Isle of Man has issued a proclamation prohibiting the +importation of cattle into the island. Tinder the same Act his +Excellency has power to subject all cattle imported into the island to a +five days' quarantine. + + +NOTE K. + +Tracing, as we have done, the sale of infected stock from abroad as far +back as the 19th of June, we find that each week that the disease has +been amongst us a fresh county has been contaminated; and more than that +when we consider that Scotland has not escaped. + + +NOTE L. + +SCOTLAND.--The cattle plague has travelled North to Aberdeenshire, and +has killed a number of animals almost simultaneously on three farms at +many miles distance from one another. The owners of stock in one of the +districts, and the Royal Northern Agricultural Association, are taking, +or resolving to take, sharp and prompt steps to stay the progress of the +disease. The committee of the association having met on Friday, +appointed a committee of inspection, arranged for a public meeting of +persons interested, and favourably entertained the notion of forming a +fund for mutual insurance against the sacrifices and losses which the +extension of the disease might occasion. A meeting of the General +Central Union was also held at Stirling on Friday, and a committee was +appointed to confer on the subject with the directors of the Highland +Society, and report to another meeting to be held next Friday.-- +_Scotsman._ + +The most important communication received to-day is from Scotland. The +malady has undoubtedly broken out near Kelso, on fourteen head of cattle +imported into London and sent north. Twenty-eight animals have been +seized with the disease at Woolwich, and calves from the London market +are said to have taken the malady down to Horsham and Grinstead. + +Information has been received concerning the sale of at least fifty-four +diseased and infected animals in the Metropolitan Cattle Market the 3rd +instant. + + +NOTE M. + +Mr. Charles Panter has, at the request of Earl Granville, drawn up a +statement relative to the health of the cows on a farm hired by his +lordship at Golder's-green, on the Finchley-road. In publishing the +statement, Earl Granville says: "When I left England, a month ago, there +were about 130 milch cows in four sheds. In the two largest and best +managed I found only one cow yesterday (Sept. 4). His Royal Highness the +Duke of Coburg informed me last week that what he believed to be the +same disease visited Coburg last year. No one could trace its origin, +and no medical treatment was successful. Air and water were their only +remedies. Some men had died from eating the meat killed at a particular +stage of the disease. His Royal Highness had seen a horse die in four +hours, killed by flies which came from the carcase of a cow which had +been allowed to remain above ground. The disease disappeared in the +autumn as mysteriously as it had come. I understand that Professor +Simonds is of opinion that the disease mentioned by the Duke of Coburg +is not the same as that from which we are suffering here--that its name +is the Siberian Pest." Mr. Panter's statement is dated Sept. 4, and is +as follows:--"On the 13th of July I purchased five Dutch cows in the +Metropolitan Market, and placed them in quarantine at Child's-hill Farm, +one mile from here. On the 22nd of July one of them showed signs of +debility; diarrhoea followed. Thinking it was only a cold, she was +treated accordingly, but continued to get worse, and died in five days. +Two more were attacked in a similar way, when veterinary advice was +called in, but in five days the whole either died or were slaughtered. +Every precaution was used to prevent the spread of infection here; the +men who attended the sick cattle were not allowed to go among the +healthy ones, and _vice versa_. But, previous to this, bearing of the +disease in the London cowsheds, I adopted precautionary measures, such +as a liberal use daily of chloride of lime, administered one ounce of +nitre in half a pint of water to each cow, and a small quantity of tar, +and painted their noses with tar. But on the 8th of August, +unfortunately, the disease showed itself here in a fat cow that had been +for ten months in the best built, best drained and ventilated shed. No +new stock had been added for nine weeks. In a few hours four more cows +showed symptoms of it. I immediately had them all removed and +slaughtered, and made a _post-mortem_ examination of them, and found the +windpipe in a state of decomposition, the lungs inflated, the small +intestines red and inflamed, and the meat of a dark yellow colour +outside, and dark red inside, which I think unfit for human food after +the first stage. The disease confined itself to the above shed of +forty-eight cows (which are now all gone) till the 20th of August, when +it broke out in another shed of thirty-five cows, some ten yards from +the former one, and continued its ravages, taking from two to four cows +daily, till they are all gone but two, one of which has not been +attacked; the other, which was a bad case, is cured, and partly come to +her milk again. On the first symptoms I had her separated from the other +stock, and did not treat her for two days, when diarrhoea set in; I +then gave her a bottle of brandy and four ounces of ground ginger in +three quarts of old ale. She lay in a kind of stupor for twelve hours, +when I could see a change in her for the better. I continued to give her +daily four quarts of gruel made with old ale and two ounces of ginger. +In four days she was sufficiently recovered to eat a little hay, &c., +and do without further treatment. In another case the above treatment +failed, and the animal died in three days. In other cases I allowed +anyone to treat them who thought they had a remedy, both professional +men and others. One persevering young veterinary surgeon came up out of +Somersetshire and treated two cases most energetically, but failed in +both; one died in four, and the other in eight days. In other cases +tonics, stimulants, blisters, and setons have been tried, but all +failed. The whole of the eighty-one cows lost were of the English breed; +we have not as yet had any loss out of the other two sheds, consisting +of about half English and half Dutch cows, and standing about forty +yards from the infected shed. It may be interesting for your lordship +to know that I had the shed at Child's-hill Farm immediately cleansed +with disinfectants, and washed with hot lime, &c., and bought twelve +fresh cows and placed them there on the 16th, which are now in perfect +health; and a neighbour situated midway between here and that farm had +twenty-three cows lying in a field; the plague took twenty of them, and +in three weeks he replaced them with new stock, which are still healthy, +he having had them a month. Another neighbour, a mile distant, had a +fine herd of seventy-two cows (English) lying in the fields a fortnight +ago. The plague broke out among them, and now he has only eight left in +health. From my own experience, and from all I can learn, I believe the +disease is atmospheric, and of a typhoid character. The first symptom in +a milking cow is an almost entire loss of milk, then loss of appetite, a +watery discharge from the eyes, nostrils, and mouth, which thickens as +the disease develops itself; rumination ceases, her ears hang down, her +eyes are heavy and sunken, bloody matter is seen in the excrement, great +debility is seen, diarrhoea sets in, and death takes place in from +three to nine days. I have read of iron water being a preventive of the +disease. All the water your cows have drunk comes six miles through +rusty iron pipes." + + +NOTE N. + +THE CATTLE MURRAIN AT HOLLY LODGE.--On the 27th of June an +Alderney bull was purchased at Bushey, near Watford, and placed with the +rest of the herd, then consisting of eleven cows, five sucking calves, +three yearling heifers, and one bull. The bull had been imported from +Alderney for several months. About a month after--namely, on the 29th of +July--a cow in calf was attacked with unusual symptoms. She was +separated from the rest; nourishing drinks were administered; but having +calved, she died forty-eight hours after the first symptoms were +observed. This led to the belief that she died of the disease which then +began to prevail. This cow had been pastured with the others in a field +occasionally used for grazing sheep that were taken to the Metropolitan +Cattle-market, and, if not sold, brought back again until the next +market day; the sheep were separated from the cows by iron hurdles. The +Holly Lodge Estate is partly bounded on the east by the route taken by +drovers with foreign and other cattle to and from the market, some of +which are also occasionally brought back to neighbouring fields. The +high road forms the western boundary within a few yards of the +cattle-sheds and pastures. These facts are stated to show that the +contagion might have been easily communicated to the animals. A few days +later three calves were attacked with cold shivering and twitching of +the muscles. The previous nights having become suddenly and unusually +cold and wet, the symptoms were at first attributed to that cause. +Although these calves had been pastured quite apart from the cow which +first died, the cow had been driven across the field where the calves +lay to the shed in which it died, the calves having been placed in the +next shed, where two of them died on the 6th of August, unmistakeably +of the cattle plague. The third calf was sent to the Royal Veterinary +College, where it also died. By the 9th of August four cows and the bull +were seized with the disease so virulently that it was thought necessary +to kill them after three days' illness. On the 12th a cow and a heifer +were also destroyed, and on the 14th one of the sucking calves died. +Thus, out of a herd of nineteen animals, twelve had died within a +fortnight. The malady had taken so strong and sudden a hold upon them +that no systematic means of remedy could be applied except separation, +warmth, stimulants, and the medicines ordinarily given in cases of cold +and fever. On the 13th of August two more cows were pronounced incurable +by two of the veterinary surgeons who had been called in; but it was +determined, upon further advice, to try a mode of treatment upon them +not hitherto adopted. One drachm of calomel was administered in gruel, +four hours afterwards one pint of castor oil, and three hours later one +quart of yeast. About two quarts of warm porter were added to a gruel of +yeast and oatmeal, and given at intervals. These remedies acted most +efficiently, and in one case gave much encouragement. The next day the +cow began to eat hay, to chew her cud, and to yield a good quantity of +milk. These remedies, together with bi-sulphate of soda, which +invariably produced a return of the milk, and quinine, were then tried +upon four other patients, with varied success. But in the end all these +cows died, not, it is believed, of the cattle murrain, but of exhaustion +occasioned by the activity of the drugs administered to them. This +belief was strengthened by the healthy appearance presented by the +viscera of the first cow thus experimented upon, on its being partially +dissected after death. The remaining cow thus treated is still alive. It +is impossible to avoid believing that had the medical man who kindly +gave his attention to these animals, been better acquainted with the +constitution of the creature, or had those who tended them had any +knowledge of medicine, three of the cows treated in this manner might +and probably would have recovered; and even when the animals succumbed +the consequences were less serious, the virulence of the poison being +expelled--at least it was undiscernible to those who dissected them. +During the fortnight that the murrain was raging, one cow in calf and +one calf remained perfectly healthy, apparently, until both were seized +within a day of each other; these had always been kept separate from the +sick animals, and tended by other men. The calf died, and the cow was +destroyed, in consequence of the symptoms being so violent. In this case +very little calomel was given. As it may be as well to mention all +particulars, it may be stated here that the men who tended the animals +were provided with a dress, and that it was found desirable that a +certain quantity of stimulants--brandy, coffee, and strong soup--should +be given to prevent nausea and other uncomfortable feelings from which +the men suffered. All the directions respecting the burying of the +animals issued by the Privy Council have been strictly complied with; +clothes, &c., have been burnt, chloride of lime (Macdougall's +disinfectant) was used with others to destroy insects and flies, with +abundance of white-washing. The men were recommended to use, as a wash +for the mouth, manganate of potash. The first crop of grass in the field +where the cattle lay before their sickness, and during it, has been +destroyed also; and it is intended to use some disinfectant, such as +charcoal or lime, to spread over the field. Miss B. C. feels so +persuaded that some mode of treatment could be found to alleviate, if +not to save life, that she has determined to employ a medical gentleman, +who kindly offers his services, and to take also the advice of a good +cow or veterinary surgeon, and to try the effects of various remedies in +some of the cowsheds where persons will be glad to let such experiments +be tried; and it is also her intention to ask the Privy Council to allow +one of the Government Inspectors to assist and report upon the cases. It +may not be altogether unimportant to add that the state of the +atmosphere seemed to have some effect upon the health of the animals, as +upon those occasions the symptoms were most severe during the +thunder-storms which then occurred. The milk which returned was found to +be rather watery, and the cream had a peculiar appearance. At first the +pigs declined it, and it was not thought advisable to continue to give +it at all to any animals for about a week. It is now perfectly good. + + +NOTE O. + +Advices from Holland, dated the Hague, Sept. 6, state: "The cattle +disease has now been observed in the parishes of Kethel, Delfshaven, +Moordrecht, Uaardingen, Averschie, Kvalingen, Nieuwerkerk on the Issel +(two hours from Rotterdam), Spykenisse, Schiedam, Herrjansdam, Maasland, +Sommelsdyk, and Zevenhuisen. It has spread most at Kethel, where it +first broke out among a cargo of cattle not admitted into England. In +the other parishes some sixty animals were infected on the 1st inst. The +post-mortem examination of the diseased beasts presents the abnormal +appearances that have been found in the disease elsewhere, _i.e._, +swollen mucous membranes with red spots, peculiar exudations in the +fourth stomach and intestines, &c. The medical commission declares the +malady to be the _typhus contagiosus bovum_ of modern veterinary +surgery, and recommends that infected animals should be treated with +from three to four drachms of muriatic acid, mixed with six ounces of +treacle and decoction of linseed. Decoctions of Peruvian bark and osier +peelings, with sulphuric ether, are also said to be beneficial to weak +animals. The avoidance of all contact of the cattle-tenders with +infected beasts is especially enjoined, and ventilation and cleanliness +of the stalls strongly recommended. Cattle markets and fairs are +suspended until further orders, and extraordinary measures for +disinfection are applied upon steamboats and railways." + + +NOTE P. + +The following document has been received at the Foreign Office from her +Majesty's Agent and Consul-General at Bucharest:-- + +(_Translation from the Official "Monitoral," No. 173, August 8-20, +1865._) + +GENERAL DIRECTION OF THE SANITARY SERVICE. + +From the 1st to the 15th July a typhus epizooty broke out among the +large horned cattle in the districts of Ilfov, Jassy, Bolgrad, Falcin, +Buzeo, and Roman, which still continues, but is on the decrease. The +Direction, in consequence, publishes the above for the information of +those concerned. + + The Director-General, + + (Signed) D. GLUCH. + + Aug. 2-14, 1865. + + +NOTE R. + +August 14. + +THE QUESTION OF INFECTION.--Yesterday afternoon Mr. Alfred +Ebsworth, of 11, Trinity-street, Southwark, the medical officer of +health for the parish of St. Mary, Newington, attended before the +sitting magistrate to make a statement with regard to the condition of +the parish from the influx of diseased cattle, and the manner in which +they were disposed of. Addressing the magistrate (Mr. Burnham) Mr. +Ebsworth said that on that morning he, in his capacity of medical +officer of health for the parish of St. Mary, Newington, received an +order to attend professionally a man who was seriously ill in +Kent-street, within the parish. While paying the visit to the patient +his attention had been drawn to the condition of a slaughter-house on +the other side of the street, where it was reported to him there were +fifteen cows which had been ordered by the Government officer to be +destroyed at the Bricklayers' Arms Station, and then to be buried. The +animals were accordingly destroyed by the men in the employ of Mr. +George Nicholls, the proprietor of the yard in question; and from Mr. +Nicholls he had learned that, instead of the carcases of the animals +being buried, they were carted through the parish of St. George's to +Mitcham, where they were boiled down, and brought back through the +parish of St. Mary, Newington, in the shape of cats'-meat. He (Mr. +Ebsworth) felt it his duty to come before the magistrate with this +complaint, especially when the cattle plague was so prevalent. He had a +right to inquire upon what grounds the carcases had not been disposed of +on the spot where they had been slaughtered, instead of being carted +through the parish he represented, in a way calculated to spread the +infection. He could not but regard this as a most iniquitous proceeding, +and he attended with a view to prevent a repetition of the practice. Mr. +Frederick T. Stanley presented himself, and said that he was a member of +the Royal College of Veterinary Surgeons. He had been appointed an +inspector of cattle under the orders issued by the Privy Council. Within +the district there were no means of burying the carcases of the diseased +and condemned animals, and in the instance referred to they could not +have been buried in the cowshed. It was impossible to bury the carcases +in the London districts, and hence they were sent to the knacker's yard, +where it was supposed they would be disposed of. Mr. Ebsworth: And +that, your worship, is what I complain of. Mr. Burcham: You think that +the practice to which you have called my attention is calculated to +propagate the extension of the disease. Mr. Stanley declared that the +skins were disinfected under his especial orders. Mr. Burcham remarked +that the animals had been taken to the slaughter-house, not for the +purpose of being killed and buried, but that their skins should be taken +off and disinfected. Why should they have been taken to Mitcham? Mr. +Stanley stated that the disease could not be communicated from a dead +animal, and it was conveyed only by inoculation, or through the breath +of a living animal upon the dead body of a diseased ox. Mr. Burcham: I +do not agree with you in that opinion. I believe that infection may be +conveyed by a dead animal. Mr. Ebsworth said that such was his opinion, +and, having regard to 28,000 patients in the parish, he had felt it his +bounden duty to come forward to make this complaint. He thought such +things ought not to occur. Mr. Burcham was of the same opinion, and that +such a commodity ought not to be allowed to be conveyed through the +public streets in open carts. Just before the magistrate was about to +rise, Mr. Stanley introduced to his worship Professor Simonds, and a +long colloquy (in private) ensued between them. At its close Professor +Simonds retired, and Mr. Burcham said: I wish to state that I wanted to +be satisfied that everything was done by Mr. Stanley that could be done +under the circumstances by which he was surrounded, in the midst of +great difficulty. I have had an interview with Professor Simonds, and he +informs me that there are the greatest difficulties, if not +impossibilities, in finding any places near London in which the dead +carcases of diseased animals can be buried. In the case now before me +these animals were slaughtered at the Bricklayers' Arms Station, and +were then taken to the slaughter-house in Kent-street, under the notion +that the owner of the slaughter-house had the means of boiling them +down. It appears that he had no such apparatus, and hence he found it +necessary to send the carcases to Mitcham, the nearest place at which he +believed the carcases could be buried and disposed of, and the +neighbourhood thereby disinfected. Professor Simonds is perfectly sure +that this meat when boiled down cannot by any probability cause the +infection to spread. It was possible, but not probable, that infection +might be introduced by the carcases of the diseased animals on their way +to the place where they had to be boiled down; but it appears to me, +from what I have just heard, that every precaution has been taken to +prevent such an occurrence. It seems that the authorities cannot find a +place within a reasonable distance in which the carcases can be buried, +and, therefore, they are obliged to have recourse to boiling them down, +as the only alternative. It is right that I should add that the conduct +of Mr. Stanley, the inspector, has been quite in conformity with the +directions he has received, not only under the Orders in Council, but +also sanctioned in my presence to-day by Professor Simonds. I trust that +this statement will remove from the mind of Mr. Stanley any unfavourable +impression he may have entertained; and I will only add my opinion, that +the diseased cattle ought to be removed through these populous +districts in closed and not in open carts. The conversation then closed, +and at an unusually late hour the court adjourned. + +DISEASED MEAT.--At the Thames Police Court yesterday Henry +Frost, an old man, was charged with having allowed to be deposited on +the premises occupied by him in the rear of the house, No. 13, +Sidney-street, Stepney, four quarters of beef prepared for sale and +intended for the food of man, but which was unfit for human food. Frost +carried on the business of a greengrocer. He asserted that he let the +place to other men, who were the actual offenders. It was intimated that +the vestry had no disposition to press for a heavy penalty. Mr. Paget +fined the prisoner 40s. At Clerkenwell, Mr. Tegg, inspector at the +Metropolitan Cattle Market for the City authorities applied to Mr. +D'Eyncourt for an order to destroy a quantity of diseased meat which he +purposed seizing. Mr. D'Eyncourt said the meat must be actually seized +and condemned upon evidence before he could make the order. In the +matter of the seizure of 32 quarters of beef, weighing about 3000 lbs., +which was found on the premises of a knacker in Pleasant-grove, +Belle-isle, Mr. D'Eyncourt dismissed an application made against the +defendant under the Nuisances Removal Act. The defence set up was that +the meat was recognised as bad and diseased by the killer as soon as the +animals were slaughtered. + + +NOTE S. + +The Orders in Council seemed only to complicate the matter, and how +effectually to combat the evil was a most difficult question. Some said +the grand remedy was the knife, and others suggested that the diseased +animals should be sent to a sanatorium. To destroy the diseased cattle +was impossible, except the owner of them or the inspector went round and +obtained an order from a magistrate for their destruction. The last +meeting was adjourned, among other purposes, in order that the committee +might take the opinion of the law officers upon the subject. It so +happened, however, that most of the law officers of the Corporation were +at present out of town. Fortunately the Common Serjeant was found, and +he gave an opinion which confirmed the committee in their view that they +had no power to kill, and no power to do anything except in the matter +of isolation. Then the committee passed a resolution that another +committee ought to be formed to raise the necessary funds for +compensating the cattle-owners, and to see that those funds were +properly applied, for the money was only intended to apply to the cattle +plague, and was not meant to go in the shape of compensation for +pleuro-pneumonia, or for the foot diseases. In other words, they were +now legislating for the cattle plague or Rinderpest only. He resided at +Dulwich, and he found that in the villages adjoining there were many +cows, and never in his life had he seen finer cows. Not one of them had +been affected by the disease. There was a cowkeeper at Peckham who had +200 cows, and all of them were in the most healthy state. At Brixton +Hill a man had 30 cows in the same excellent condition. At Dulwich +nearly all the cows were diseased, but there the shed and other +accommodation was exceedingly bad. In parts of Peckham Rye some of the +cowkeepers had lost their cattle, but there again the places were badly +ventilated, and the cows were badly cared for. He believed that the +disease might be prevented by the use of proper precautions on the part +of those who had the greatest interest in keeping their cows in a +healthy state. He believed, too, that this question affected the whole +of the metropolitan district quite as much as it did the City itself. +There were no fewer than 106 head of diseased cattle lately seized; but, +as he said before, they could not be killed without an order from a +magistrate, and a magistrate would naturally feel a difficulty in +issuing an order to kill so many as 106 head. It was necessary, under +such circumstances, that a deputation should wait upon the Home +Secretary and ask him to provide a remedy, and tell the authorities what +they were to do at such a crisis. If, as it now appeared, the inspectors +and the markets' committee had been slaughtering beasts without +authority, who was to pay the costs should proceedings against them be +commenced? Professor Simonds seemed to think that next session a bill of +indemnity would be introduced, and certainly something of this kind was +rendered necessary, for cattle were now coming here which were consigned +to A., B., and C., and then the owners could not be found, and without +the consent of the owners the diseased beasts could not be killed. The +next subject in the report had reference to slaughter-houses. As there +were no places at present to which cattle in an incipient stage of the +disease could be removed from the sheds in which they were placed along +with untainted cattle, it was now proposed that slaughter-houses should +be established in London for their reception. Then came the question, +how were the beasts to be removed from the sheds to the +slaughter-houses? It was the opinion of many that they ought to be +removed in vans, and not driven through the streets; but, however that +might be, slaughter-houses should be erected in the metropolis where the +tainted animals might be killed. Then came the question, how was an +animal to be dealt with when first stricken with the disease? It was +suggested that hospitals or sanatoriums should be provided, to which the +beasts should be sent. But this was a matter of great importance, to +which the attention of the committee to be appointed and that of the +medical men would have to be directed. If the plague went on it would +affect all classes, rich and poor alike, and instead of meat being as +now at a reasonable rate, it would go up 4_d._ or 6_d._ per pound; but +he had hopes that the disease might be checked, particularly as +Professors Simonds and Gamgee had been more successful in the treatment +of it than they had previously been. + + +NOTE T. + +August 31. + +DEPUTATION TO THE HOME OFFICE.--Yesterday afternoon the Lord +Mayor proceeded from the Mansion House to the Home Office, and had an +interview with Mr. Waddington on the subject of the cattle plague, and +the desirability of establishing hospitals or sanatoriums within the +metropolitan districts for the reception and medical treatment of +diseased cattle. His lordship was accompanied on the occasion by the +following deputation from the Markets and Cattle Plague Committees:--Mr. +Gibbins (Chairman of the Markets Committee), Mr. Webber, Mr. Gower, Mr. +Brewster, Mr. Rudkin, and Dr. Jarvis (the Medical Officer of Health for +Bethnal-green). Sir George Grey having left London for Falloden. + +The Lord Mayor introduced the deputation to Mr. Waddington, and in doing +so, said that their object was to obtain the sanction of Government to +the establishment of hospitals or sanatoriums within the metropolitan +districts, to which diseased cattle could be conveyed from the cowsheds +in order that they might there receive medical treatment, and be, if +possible, restored to health. He observed that similar establishments +had been formed at Edinburgh and other large towns, and that they had +been found to work most satisfactorily, not only in separating the +diseased cattle from those which were non-diseased, but in affording +facilities to the medical profession to exercise their skill and +knowledge under circumstances more favourable to a fair trial of both +than they could expect to find in crowded cowsheds, many of which were +in a filthy condition and badly ventilated. He pointed out the progress +the plague had made, and was still making, in the metropolis, and how +its effects upon the high price of meat and milk were affecting all +classes of the community. The difficulties, he said, of adequately +meeting the necessities of the case were at present very great, and some +of these consisted in the alleged illegality of slaughtering diseased +animals without an order from a magistrate, and also the illegality of +removing those diseased from the cowsheds to the hospitals, supposing +the latter to exist. But he hoped the Government, who had no doubt well +considered a subject of such vast importance, would speedily do away +with those difficulties, and render the fullest aid to the Markets' +Committee and Metropolitan Cattle Plague Committee, who were unceasingly +devoting their time and attention to mitigate, and, if possible, put an +end to the evil. At present, however, the object of the deputation was +limited to that of obtaining the sanction of the Government to the +establishment of the hospitals or sanatoriums. This was an object which +had not only received the general approval of the two committees +mentioned, but also of the medical profession, and he might add, what it +was by no means unimportant to bear in mind, that the cowkeepers +themselves and the salesmen of the Cattle Market were also in favour of +it. + +Mr. Gibbins and the several members of the deputation corroborated what +had fallen from the Lord Mayor, and strongly advocated the necessity of +having the hospitals speedily established. + +Mr. Rudkin called the attention of Mr. Waddington to the fact that the +day before there were fourteen diseased cows seized at the +slaughter-house of the Cattle Market, which had been sent there from the +cowsheds of the metropolis. He argued that this in itself was a proof +that the Order in Council, as at present carried out, was insufficient +to prevent diseased cows from being sent from the cowsheds by their +owners to be slaughtered for human food. + +Mr. Waddington, who listened very attentively to the whole of the +statements, said he would take an early opportunity of communicating +with Sir George Grey upon the subject. In the first instance, however, +he wished the deputation to forward to him their views in writing, and +these also would be transmitted to the Home Secretary. + +The deputation promised to comply with the suggestion, and thanked Mr. +Waddington for the courtesy with which he had received and the patience +with which he had listened to them. + +YORKSHIRE.--The plague has extended to this district. The cases +reported, however, are extremely few, and precautions are being taken +which it is hoped may stop the further progress of the disease. On +Tuesday a meeting of the Yorkshire Medical Veterinary Society was held +at Leeds, and the question was discussed in all its bearings. It was +stated that four cases had occurred in Leeds, and the disease has also +appeared in the Skyrack division of the Riding. The general result of +the discussion was, that members of the society were recommended, when +diseased cattle were submitted, not to order them to be killed, but to +place them in a sanatorium for medicinal treatment; the wholesale +destruction of the animals being regarded as a blot upon the profession. + + +NOTE V. + +Indeed, information has reached us of the disease existing in +Dumfriesshire, but there is some doubt on this point. So long as we hear +of infected, or probably infected, cattle being disseminated in large +numbers from the great markets of the country, we must have the +propagation of the malady. For the welfare of this country, it is deeply +to be regretted that our Government cannot deal with this question as +Continental authorities do. _I regret to say some of our neighbours +laugh at our expense._ They see us helpless owing to the wretched state +of our laws on the subject, and they are not a little amused at the +theories of spontaneous development of the disease which some still +advocate. The French Emperor has sent over Professor Bouley, who is +still in this country, and who telegraphed on his first arrival, about +ten days ago, that the ports of France should be instantly closed to +British cattle. This has been done, and we may depend upon it the French +people will not suffer as we now must.--GAMGEE, _Lettre du 24 Aout_. + + +NOTE Y. + +August 16. + +MORE SEIZURES OF DISEASED MEAT.--Yesterday Mr. Paget, in the +course of the proceedings at the Thames Police Court, was informed that +there was a large quantity of meat in a van in the police-yard +adjoining, which had been seized that day by Mr. J. Stevens, the +sanitary inspector of Mile-end Old Town, and which was described as +unfit for human food. The inspector stated, that in consequence of +having been informed that there was a quantity of diseased meat at the +shop of Mr. Frost, butcher, Sydney-street, Mile-end Old Town, he went +there that morning, and found four quarters of beef (two fore and two +hind quarters) which were from a diseased beast. He made a seizure of +them, and heard that the animal had been sent by a person of the name of +Stephens, a cowkeeper in business on Bow-common. The meat was in a very +nasty state, and totally unfit for human food. (Mr. Paget went into the +police-yard to examine the meat, which was in a very shocking state.) +Dr. Freeman, Medical Officer of Health of the Hamlet of Mile-end Old +Town, stated that his attention was called to the state of the meat by +the sanitary inspector. He examined it, and gave his opinion that it +should be destroyed, as it was not only in a diseased condition, but he +believed that it had died from some disease. Mr. Paget: Can you state +the nature of the disease which caused its death?--Witness: I cannot. +Most likely it was the prevailing epidemic; and if it were eaten it +would be very injurious. Mr. Paget, after hearing the evidence, ordered +that the meat should be immediately destroyed, when the inspector took +the van with its contents to a knacker's yard to see the order carried +into effect. + + +NOTE Z. + +NEFARIOUS ATTEMPT TO SPREAD THE PLAGUE.--Yesterday Mr. Gifford, +Sanitary Inspector to the parish of Paddington, asked (at Marylebone +Police Court) for the magistrate's advice under the following +circumstances:--Applicant said that, in consequence of information +received, he yesterday went to a cowshed situate on the Maryland Farm, +Harrow-road. He found the door fastened. On looking through one of the +chinks, he saw a cow which apparently was in the worst stage of the now +prevailing disease, and his opinion was verified after he had burst open +the door and examined the animal. He subsequently ascertained that the +diseased cow had been brought some distance by a man who was at feud +with the owner of the Maryland Farm, and surreptitiously placed amongst +the healthy cattle. This was the first case where the disease had shown +itself in the parish of Paddington. Mr. Yardley referred the applicant +to the Order in Council, dated the 24th of July, 1865, under which he +thought inspectors of nuisances had power to act summarily. + + +THE END. + + + LONDON: + SAVILL AND EDWARDS, PRINTERS, CHANDOS STREET, + COVENT GARDEN. + + + + + +-----------------------------------------------+ + | Transcriber's Note: | + | | + | Inconsistent hyphenation and spelling in the | + | original document have been preserved. | + | | + | Greek words are transliterated and marked | + | +like so+ | + | | + | Typographical errors corrected in the text: | + | | + | Page 62 Ge11e changed to Gelle | + | Page 67 Bruneleschi changed to Brunelleschi | + | Page 142 Roeol changed to Roell | + | Page 175 charboneux changed to charbonneux | + | Page 253 eat changed to ate | + | Page 354 lairs changed to fairs | + | Page 377 Boulay changed to Bouley | + +-----------------------------------------------+ + + + + + +End of the Project Gutenberg EBook of On the cattle plague: or, Contagious +typhus in horned cattle. 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