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diff --git a/old/thx1910.txt b/old/thx1910.txt new file mode 100644 index 0000000..7257a23 --- /dev/null +++ b/old/thx1910.txt @@ -0,0 +1,1027 @@ +**The Project Gutenberg Etext of The Circulation of the Blood** +#39 in our series by Thomas H. Huxley + +Copyright laws are changing all over the world, be sure to check +the laws for your country before redistributing these files!!! + +Please take a look at the important information in this header. +We encourage you to keep this file on your own disk, keeping an +electronic path open for the next readers. + +Please do not remove this. + +This should be the first thing seen when anyone opens the book. +Do not change or edit it without written permission. 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Huxley + + + + +THE CIRCULATION OF THE BLOOD* + +[*footnote] A Lecture delivered in the Free Trade Hall, November 2nd, +1878. + +I DESIRE this evening to give you some account of the life and labours +of a very noble Englishman--William Harvey. + +William Harvey was born in the year 1578, and as he lived until the year +1657, he very nearly attained the age of 80. He was the son of a small +landowner in Kent, who was sufficiently wealthy to send this, his +eldest son, to the University of Cambridge; while he embarked the +others in mercantile pursuits, in which they all, as time passed on, +attained riches. + +William Harvey, after pursuing his education at Cambridge, and taking +his degree there, thought it was advisable--and justly thought so, in +the then state of University education--to proceed to Italy, which at +that time was one of the great centres of intellectual activity in +Europe, as all friends of freedom hope it will become again, sooner or +later. In those days the University of Padua had a great renown; and +Harvey went there and studied under a man who was then very +famous--Fabricius of Aquapendente. On his return to England, Harvey +became a member of the College of Physicians in London, and entered +into practice; and, I suppose, as an indispensable step thereto, +proceeded to marry. He very soon became one of the most eminent +members of the profession in London; and, about the year 1616, he was +elected by the College of Physicians their Professor of Anatomy. It +was while Harvey held this office that he made public that great +discovery of the circulation of the blood and the movements of the +heart, the nature of which I shall endeavour by-and-by to explain to you +at length. Shortly afterwards, Charles the First having succeeded to +the throne in 1625, Harvey became one of the king's physicians; and it +is much to the credit of the unfortunate monarch--who, whatever his +faults may have been, was one of the few English monarchs who have shown +a taste for art and science--that Harvey became his attached and +devoted friend as well as servant; and that the king, on the other +hand, did all he could to advance Harvey's investigations. But, as you +know, evil times came on; and Harvey, after the fortunes of his royal +master were broken, being then a man of somewhat advanced years--over +60 years of age, in fact--retired to the society of his brothers in and +near London, and among them pursued his studies until the day of his +death. Harvey's career is a life which offers no salient points of +interest to the biographer. It was a life devoted to study and +investigation; and it was a life the devotion of which was amply +rewarded, as I shall have occasion to point out to you, by its results. + +Harvey, by the diversity, the variety, and the thoroughness of his +investigations, was enabled to give an entirely new direction to at +least two branches--and two of the most important branches--of what +now-a-days we call Biological Science. On the one hand, he founded all +our modern physiology by the discovery of the exact nature of the +motions of the heart, and of the course in which the blood is propelled +through the body; and, on the other, he laid the foundation of that +study of development which has been so much advanced of late years, and +which constitutes one of the great pillars of the doctrine of evolution. +This doctrine, I need hardly tell you, is now tending to revolutionise +our conceptions of the origin of living things, exactly in the same way +as Harvey's discovery of the circulation in the seventeeth century +revolutionised the conceptions which men had previously entertained with +regard to physiological processes. + +It would, I regret, be quite impossible for me to attempt, in the course +of the time I can presume to hold you here, to unfold the history of +more than one of these great investigations of Harvey. I call them +"great investigations," as distinguished from "large publications." I +have in my hand a little book, which those of you who are at a great +distance may have some difficulty in seeing, and which I value very +much. It is, I am afraid, sadly thumbed and scratched with annotations +by a very humble successor and follower of Harvey. This little book is +the edition of 1651 of the 'Exercitationes de Generatione'; and if you +were to add another little book, printed in the same small type, and +about one-seventh of the thickness, you would have the sum total of the +printed matter which Harvey contributed to our literature. And yet in +that sum total was contained, I may say, the materials of two +revolutions in as many of the main branches of biological science. If +Harvey's published labours can be condensed into so small a compass, +you must recollect that it is not because he did not do a great deal +more. We know very well that he did accumulate a very considerable +number of observations on the most varied topics of medicine, surgery, +and natural history. But, as I mentioned to you just now, Harvey, for +a time, took the royal side in the domestic quarrel of the Great +Rebellion, as it is called; and the Parliament, not unnaturally +resenting that action of his, sent soldiers to seize his papers. And +while I imagine they found nothing treasonable among those papers, yet, +in the process of rummaging through them, they destroyed all the +materials which Harvey had spent a laborious life in accumulating; and +hence it is that the man's work and labours are represented by so +little in apparent bulk. + +What I chiefly propose to do to-night is to lay before you an account of +the nature of the discovery which Harvey made, and which is termed the +Discovery of the Circulation of the Blood. And I desire also, with +some particularity, to draw your attention to the methods by which that +discovery was achieved; for, in both these respects, I think, there will +be much matter for profitable reflection. + +Let me point out to you, in the first place, with respect to this +important matter of the movements of the heart and the course of the +blood in the body, that there is a certain amount of knowledge which +must have been obtained without men taking the trouble to seek +it--knowledge which must have been taken in, in the course of time, by +everybody who followed the trade of a butcher, and still more so by +those people who, in ancient times, professed to divine the course of +future events from the entrails of animals. It is quite obvious to +all, from ordinary accidents, that the bodies of all the higher animals +contain a hot red fluid--the blood. Everybody can see upon the surface +of some part of the skin, underneath that skin, pulsating tubes, which +we know as the arteries. Everybody can see under the surface of the +skin more delicate and softer looking tubes, which do not pulsate, which +are of a bluish colour, and are termed the veins. And every person who +has seen a recently killed animal opened knows that these two kinds of +tubes to which I have just referred, are connected with an apparatus +which is placed in the chest, which apparatus, in recently killed +animals, is still pulsating. And you know that in yourselves you can +feel the pulsation of this organ, the heart, between the fifth and +sixth ribs. I take it that this much of anatomy and physiology has +been known from the oldest times, not only as a matter of curiosity, +but because one of the great objects of men, from their earliest +recorded existence, has been to kill one another, and it was a matter +of considerable importance to know which was the best place for hitting +an enemy. I can refer you to very ancient records for most precise and +clear information that one of the best places is to smite him between +the fifth and sixth ribs. Now that is a very good piece of regional +anatomy, for that is the place where the heart strikes in its +pulsations, and the use of smiting there is that you go straight to the +heart. Well, all that must have been known from time immemorial--at +least for 4,000 or 5,000 years before the commencement of our +era--because we know that for as great a period as that the Egyptians, +at any rate, whatever may have been the case with other people, were in +the enjoyment of a highly developed civilisation. But of what +knowledge they may have possessed beyond this we know nothing; and in +tracing back the springs of the origin of everything that we call +"modern science" (which is not merely knowing, but knowing +systematically, and with the intention and endeavour to find out the +causal connection of things)--I say that when we trace back the +different lines of all the modern sciences we come at length to one +epoch and to one country--the epoch being about the fourth and fifth +centuries before Christ, and the country being ancient Greece. It is +there that we find the commencement and the root of every branch of +physical science and of scientific method. If we go back to that time +we have in the works attributed to Aristotle, who flourished between +300 and 400 years before Christ, a sort of encyclopaedia of the +scientific knowledge of that day--and a very marvellous collection of, +in many respects, accurate and precise knowledge it is. But, so far as +regards this particular topic, Aristotle, it must be confessed, has not +got very far beyond common knowledge. He knows a little about the +structure of the heart. I do not think that his knowledge is so +inaccurate as many people fancy, but it does not amount to much. A very +few years after his time, however, there was a Greek philosopher, +Erasistratus, who lived about three hundred years before Christ, and +who must have pursued anatomy with much care, for he made the important +discovery that there are membranous flaps, which are now called +"valves," at the origins of the great vessels; and that there are +certain other valves in the interior of the heart itself. + +Fig. 1.--The apparatus of the circulation, as at present known. The +capillary vessels, which connect the arteries and veins, are omitted, +on account of their small size. The shading of the "venous system" is +given to all the vessels which contain venous blood; that of the +"arterial system" to all the vessels which contain arterial blood. + +I have here (Fig. 1) a purposely rough, but, so far as it goes, +accurate, diagram of the structure of the heart and the course of the +blood. The heart is supposed to be divided into two portions. It +would be possible, by very careful dissection, to split the heart down +the middle of a partition, or so-called 'septum', which exists in it, +and to divide it into the two portions which you see here represented; +in which case we should have a left heart and a right heart, quite +distinct from one another. You will observe that there is a portion of +each heart which is what is called the ventricle. Now the ancients +applied the term 'heart' simply and solely to the ventricles. They did +not count the rest of the heart--what we now speak of as the +'auricles'--as any part of the heart at all; but when they spoke of the +heart they meant the left and the right ventricles; and they described +those great vessels, which we now call the 'pulmonary veins' and the +'vena cava', as opening directly into the heart itself. + +What Erasistratus made out was that, at the roots of the aorta and the +pulmonary artery (Fig. 1) there were valves, which opened in the +direction indicated by the arrows; and, on the other hand, that at the +junction of what he called the veins with the heart there were other +valves, which also opened again in the direction indicated by the +arrows. This was a very capital discovery, because it proved that if +the heart was full of fluid, and if there were any means of causing +that fluid in the ventricles to move, then the fluid could move only in +one direction; for you will observe that, as soon as the fluid is +compressed, the two valves between the ventricles and the veins will be +shut, and the fluid will be obliged to move into the arteries; and, if +it tries to get back from them into the heart, it is prevented from +doing so by the valves at the origin of the arteries, which we now call +the semilunar valves (half-moon shaped valves); so that it is +impossible, if the fluid move at all, that it should move in any other +way than from the great veins into the arteries. Now that was a very +remarkable and striking discovery. + +But it is not given to any man to be altogether right (that is a +reflection which it is very desirable for every man who has had the +good luck to be nearly right once, always to bear in mind); and +Erasistratus, while he made this capital and important discovery, made a +very capital and important error in another direction, although it was +a very natural error. If, in any animal which is recently killed, you +open one of those pulsating trunks which I referred to a short time +ago, you will find, as a general rule, that it either contains no blood +at all or next to none; but that, on the contrary, it is full of air. +Very naturally, therefore, Erasistratus came to the conclusion that +this was the normal and natural state of the arteries, and that they +contained air. We are apt to think this a very gross blunder; but, to +anybody who is acquainted with the facts of the case, it is, at first +sight, an exceedingly natural conclusion. Not only so, but Erasistratus +might have very justly imagined that he had seen his way to the meaning +of the connection of the left side of the heart with the lungs; for we +find that what we now call the pulmonary vein is connected with the +lungs, and branches out in them (Fig. 1). Finding that the greater part +of this system of vessels was filled with air after death, this ancient +thinker very shrewdly concluded that its real business was to receive +air from the lungs, and to distribute that air all through the body, so +as to get rid of the grosser humours and purify the blood. That was a +very natural and very obvious suggestion, and a highly ingenious one, +though it happened to be a great error. You will observe that the only +way of correcting it was to experiment upon living animals, for there +is no other way in which this point could be settled. + +Fig.2,--The Course of the Blood according to Galen (A.D. 170). + +And hence we are indebted, for the correction of the error of +Erasistratus, to one of the greatest experimenters of ancient or modern +times, Claudius Galenus, who lived in the second century after Christ. +I say it was to this man more than any one else, because he knew that +the only way of solving physiological problems was to examine into the +facts in the living animal. And because Galen was a skilful anatomist, +and a skilful experimenter, he was able to show in what particulars +Erasistratus had erred, and to build up a system of thought upon this +subject which was not improved upon for fully 1,300 years. I have +endeavoured, in Fig. 2, to make clear to you exactly what it was he +tried to establish. You will observe that this diagram is practically +the same as that given in Fig. 1, only simplified. The same facts may +be looked upon by different people from different points of view. Galen +looked upon these facts from a very different point of view from that +which we ourselves occupy; but, so far as the facts are concerned, they +were the same for him as for us. Well then, the first thing that Galen +did was to make out experimentally that, during life, the arteries are +not full of air, but that they are full of blood. And he describes a +great variety of experiments which he made upon living animals with the +view of proving this point, which he did prove effectually and for all +time; and that you will observe was the only way of settling the +matter. Furthermore, he demonstrated that the cavities of the left +side of the heart--what we now call the left auricle and the left +ventricle--are, like the arteries, full of blood during life, and that +that blood was of the scarlet kind--arterialised, or as he called it +"pneumatised," blood. It was known before, that the pulmonary artery, +the right ventricle, and the veins, contain the darker kind of blood, +which was thence called venous. Having proved that the whole of the +left side of the heart, during life, is full of scarlet arterial blood, +Galen's next point was to inquire into the mode of communication +between the arteries and veins. It was known before his time that both +arteries and veins branched out. Galen maintained, though he could not +prove the fact, that the ultimate branches of the arteries and veins +communicated together somehow or other, by what he called +'anastomoses', and that these 'anastomoses' existed not only in the body +in general but also in the lungs. In the next place, Galen maintained +that all the veins of the body arise from the liver; that they draw the +blood thence and distribute it over the body. People laugh at that +notion now-a-days; but if anybody will look at the facts he will see +that it is a very probable supposition. There is a great vein (hepatic +vein--Fig. 1) which rises out of the liver, and that vein goes straight +into the 'vena cava' (Fig. 1) which passes to the heart, being there +joined by the other veins of the body. The liver itself is fed by a +very large vein (portal vein--Fig. 1), which comes from the alimentary +canal. The way the ancients looked at this matter was, that the food, +after being received into the alimentary canal, was then taken up by the +branches of this great vein, which are called the 'vena portae', just +as the roots of a plant suck up nourishment from the soil in which it +lives; that then it was carried to the liver, there to be what was +called "concocted," which was their phrase for its conversion into +substances more fitted for nutrition than previously existed in it. +They then supposed that the next thing to be done was to distribute +this fluid through the body; and Galen like his predecessors, imagined +that the "concocted" blood, having entered the great 'vena cava', was +distributed by its ramifications all over the body. So that, in his +view (Fig. 2), the course of the blood was from the intestine to the +liver, and from the liver into the great 'vena cava', including what we +now call the right auricle of the heart, whence it was distributed by +the branches of the veins. But the whole of the blood was not thus +disposed of. Part of the blood, it was supposed, went through what we +now call the pulmonary arteries (Fig. 1), and, branching out there, gave +exit to certain "fuliginous" products, and at the same time took in +from the air a something which Galen calls the 'pneuma'. He does not +know anything about what we call oxygen; but it is astonishing how very +easy it would be to turn his language into the equivalent of modern +chemical theory. The old philosopher had so just a suspicion of the +real state of affairs that you could make use of his language in many +cases, if you substituted the word "oxygen," which we now-a-days use, +for the word 'pneuma'. Then he imagined that the blood, further +concocted or altered by contact with the 'pneuma', passed to a certain +extent to the left side of the heart. So that Galen believed that +there was such a thing as what is now called the pulmonary +circulation. He believed, as much as we do, that the blood passed +through the right side of the heart, through the artery which goes to +the lungs, through the lungs themselves, and back by what we call the +pulmonary veins to the left side of the heart. But he thought it was +only a very small portion of the blood which passes to the right side of +the heart in this way; the rest of the blood, he thought, passed +through the partition which separates the two ventricles of the heart. +He describes a number of small pits, which really exist there, as +holes, and he supposed that the greater part of the blood passed +through these holes from the right to the left ventricle (Fig 2). + +It is of great importance you should clearly understand these teachings +of Galen, because, as I said just now, they sum up all that anybody +knew until the revival of learning; and they come to this--that the +blood having passed from the stomach and intestines through the liver, +and having entered the great veins, was by them distributed to every +part of the body; that part of the blood, thus distributed, entered the +arterial system by the 'anastomoses', as Galen called them, in the +lungs; that a very small portion of it entered the arteries by the +'anastomoses' in the body generally; but that the greater part of it +passed through the septum of the heart, and so entered the left side +and mingled with the pneumatised blood, which had been subjected to the +air in the lungs, and was then distributed by the arteries, and +eventually mixed with the currents of blood, coming the other way, +through the veins. + +Yet one other point about the views of Galen. He thought that both the +contractions and dilatations of the heart--what we call the 'systole' +or contraction of the heart, and the 'diastole' or dilatation--Galen +thought that these were both active movements; that the heart actively +dilated, so that it had a sort of sucking power upon the fluids which +had access to it. And again, with respect to the movements of the +pulse, which anybody can feel at the wrist and elsewhere, Galen was of +opinion that the walls of the arteries partook of that which he +supposed to be the nature of the walls of the heart, and that they had +the power of alternately actively contracting and actively dilating, so +that he is careful to say that the nature of the pulse is comparable, +not to the movement of a bag, which we fill by blowing into it, and +which we empty by drawing the air out of it, but to the action of a +bellows, which is actively dilated and actively compressed. + +Fig 3.--The course of the blood from the right to the left side of the +heart (Realdus Columbus, 1559). + +After Galen's time came the collapse of the Roman Empire, the extinction +of physical knowledge, and the repression of every kind of scientific +inquiry, by its powerful and consistent enemy, the Church; and that +state of things lasted until the latter part of the Middle Ages saw the +revival of learning. That revival of learning, so far as anatomy and +physiology are concerned, is due to the renewed influence of the +philosophers of ancient Greece, and indeed, of Galen. Arabic +commentators had translated Galen, and portions of his works had got +into the language of the learned in the Middle Ages, in that way; but, +by the study of the classical languages, the original text became +accessible to the men who were then endeavouring to learn for +themselves something about the facts of nature. It was a century or +more before these men, finding themselves in the presence of a +master--finding that all their lives were occupied in attempting to +ascertain for themselves that which was familiar to him--I say it took +the best part of a hundred years before they could fairly see that their +business was not to follow him, but to follow his example--namely, to +look into the facts of nature for themselves, and to carry on, in his +spirit, the work he had begun. That was first done by Vesalius, one of +the greatest anatomists who ever lived; but his work does not specially +bear upon the question we are now concerned with. So far as regards +the motions of the heart and the course of the blood, the first man in +the Middle Ages, and indeed the only man who did anything which was of +real importance, was one Realdus Columbus, who was professor at Padua +in the year 1559, and published a great anatomical treatise. What +Realdus Columbus did was this; once more resorting to the method of +Galen, turning to the living animal, experimenting, he came upon new +facts, and one of these new facts was that there was not merely a +subordinate communication between the blood of the right side of the +heart and that of the left side of the heart, through the lungs, but +that there was a constant steady current of blood, setting through the +pulmonary artery on the right side, through the lungs, and back by the +pulmonary veins to the left side of the heart (Fig.3). Such was the +capital discovery and demonstration of Realdus Columbus. He is the man +who discovered what is loosely called the 'pulmonary circulation'; and +it really is quite absurd, in the face of the fact, that twenty years +afterwards we find Ambrose Pare, the great French surgeon, ascribing +this discovery to him as a matter of common notoriety, to find that +attempts are made to give the credit of it to other people. So far as +I know, this discovery of the course of the blood through the lungs, +which is called the pulmonary circulation, is the one step in real +advance that was made between the time of Galen and the time of +Harvey. And I would beg you to note that the word "circulation" is +improperly employed when it is applied to the course of the blood +through the lungs. The blood from the right side of the heart, in +getting to the left side of the heart, only performs a half-circle--it +does not perform a whole circle--it does not return to the place from +whence it started; and hence the discovery of the so-called "pulmonary +circulation" has nothing whatever to do with that greater discovery +which I shall point out to you by-and-by was made by Harvey, and which +is alone really entitled to the name of the circulation of the blood. + +If anybody wants to understand what Harvey's great desert really was, I +would suggest to him that he devote himself to a course of reading, +which I cannot promise shall be very entertaining, but which, in this +respect at any rate, will be highly instructive--namely, the works of +the anatomists of the latter part of the 16th century and the beginning +of the 17th century. If anybody will take the trouble to do that which +I have thought it my business to do, he will find that the doctrines +respecting the action of the heart and the motion of the blood which +were taught in every university in Europe, whether in Padua or in Paris, +were essentially those put forward by Galen, 'plus' the discovery of +the pulmonary course of the blood which had been made by Realdus +Columbus. In every chair of anatomy and physiology (which studies were +not then separated) in Europe, it was taught that the blood brought to +the liver by the portal vein, and carried out of the liver to the 'vena +cava' by the hepatic vein, is distributed from the right side of the +heart, through the other veins, to all parts of the body; that the +blood of the arteries takes a like course from the heart towards the +periphery; and that it is there, by means of the 'anastomoses', more or +less mixed up with the venous blood. It so happens, by a curious +chance, that up to the year 1625 there was at Padua, which was Harvey's +own university, a very distinguished professor, Spigelius, whose work +is extant, and who teaches exactly what I am now telling you. It is +perfectly true that, some time before, Harvey's master, Fabricius, had +not only re-discovered, but had drawn much attention to certain +pouch-like structures, which are called the valves of the veins, found +in the muscular parts of the body, all of which are directed towards +the heart, and consequently impede the flow of the blood in the +opposite direction. And you will find it stated by people who have not +thought much about the matter, that it was this discovery of the valves +of the veins which led Harvey to imagine the course of the circulation +of the blood. Now it did not lead Harvey to imagine anything of the +kind. He had heard all about it from his master, Fabricius, who made a +great point of these valves in the veins, and he had heard the theories +which Fabricius entertained upon the subject, whose impression as to +the use of the valves was simply this--that they tended to take off any +excess of pressure of the blood in passing from the heart to the +extremities; for Fabricius believed, with the rest of the world, that +the blood in the veins flowed from the heart towards the extremities. +This, under the circumstances, was as good a theory as any other, +because the action of the valves depends altogether upon the form and +nature of the walls of the structures in which they are attached; and +without accurate experiment, it was impossible to say whether the +theory of Fabricius was right or wrong. But we not only have the +evidence of the facts themselves that these could tell Harvey nothing +about the circulation, but we have his own distinct declaration as to +the considerations which led him to the true theory of the circulation +of the blood, and amongst these the valves of the veins are not +mentioned. + +Fig. 4.--The circulation of the blood as demonstrated by Harvey (A.D. +1628). + +Now then we may come to Harvey himself. When you read Harvey's +treatise, which is one of the most remarkable scientific monographs +with which I am acquainted--it occupies between 50 and 60 pages of a +small quarto in Latin, and is as terse and concise as it possibly can +be--when you come to look at Harvey's work, you will find that he had +long struggled with the difficulties of the accepted doctrine of the +circulation. He had received from Fabricius, and from all the great +authorities of the day, the current view of the circulation of the +blood. But he was a man with that rarest of all +qualities--intellectual honesty; and by dint of cultivating that great +faculty, which is more moral than intellectual, it had become impossible +for him to say he believed anything which he did not clearly believe. +This is a most uncomfortable peculiarity--for it gets you into all +sorts of difficulties with all sorts of people--but, for scientific +purposes, it is absolutely invaluable. Harvey possessed this +peculiarity in the highest degree, and so it was impossible for him to +accept what all the authorities told him, and he looked into the matter +for himself. But he was not hasty. He worked at his new views, and he +lectured about them at the College of Physicians for nine years; he did +not print them until he was a man of fifty years of age; and when he +did print them he accompanied them with a demonstration which has never +been shaken, and which will stand till the end of time. What Harvey +proved, in short, was this (see Fig. 4)--that everybody had made a +mistake, for want of sufficiently accurate experimentation as to the +actual existence of the fact which everybody assumed. To anybody who +looks at the blood-vessels with an unprejudiced eye it seems so natural +that the blood should all come out of the liver, and be distributed by +the veins to the different parts of the body, that nothing can seem +simpler or more plain; and consequently no one could make up his mind +to dispute this apparently obvious assumption. But Harvey did dispute +it; and when he came to investigate the matter he discovered that it was +a profound mistake, and that, all this time, the blood had been moving +in just the opposite direction, namely, from the small ramifications of +the veins towards the right side of the heart. Harvey further found +that, in the arteries, the blood, as had previously been known, was +travelling from the greater trunks towards the ramifications. Moreover, +referring to the ideas of Columbus and of Galen (for he was a great +student of literature, and did justice to all his predecessors), Harvey +accepts and strengthens their view of the course of the blood through +the lungs, and he shows how it fitted into his general scheme. If you +will follow the course of the arrows in Fig. 4 you will see at once +that--in accordance with the views of Columbus--the blood passes from +the right side of the heart, through the lungs, to the left side. Then, +adds Harvey, with abundant proof, it passes through the arteries to all +parts of the body; and then, at the extremities of their branches in +the different parts of the body, it passes (in what way he could not +tell, for his means of investigation did not allow him to say) into the +roots of the vents--then from the roots of the veins it goes into the +trunk and veins--then to the right side of the heart--and then to the +lungs, and so on. + +That, you will observe, makes a complete circuit; and it was precisely +here that the originality of Harvey lay. There never yet has been +produced, and I do not believe there can be produced, a tittle of +evidence to show that, before his time, any one had the slightest +suspicion that a single drop of blood, starting in the left ventricle +of the heart, passes through the whole arterial system, comes back +through the venous system, goes through the lungs, and comes back to +the place whence it started. But that is the circulation of the blood, +and it was exactly this which Harvey was the first man to suspect, to +discover, and to demonstrate. + +But this was by no means the only thing Harvey did. He was the first +who discovered and who demonstrated the true mechanism of the heart's +action. No one, before his time, conceived that the movement of the +blood was entirely due to the mechanical action of the heart as a +pump. There were all sorts of speculations about the matter, but nobody +had formed this conception, and nobody understood that the so-called +systole of the heart is a state of active contraction, and the +so-called diastole is a mere passive dilatation. Even within our own +age that matter had been discussed. Harvey is as clear as possible +about it. He says the movement of the blood is entirely due to the +contractions of the walls of the heart--that it is the propelling +apparatus--and all recent investigation tends to show that he was +perfectly right. And from this followed the true theory of the pulse. +Galen said, as I pointed out just now, that the arteries dilate as +bellows, which have an active power of dilatation and contraction, and +not as bags which are blown out and collapse. Harvey said it was +exactly the contrary--the arteries dilate as bags simply because the +stroke of the heart propels the blood into them; and, when they relax +again, they relax as bags which are no longer stretched, simply because +the force of the blow of the heart is spent. Harvey has been +demonstrated to be absolutely right in this statement of his; and yet, +so slow is the progress of truth, that, within my time, the question of +the active dilatation of the arteries has been discussed. + +Thus Harvey's contributions to physiology may be summed up as follows: +In the first place, he was the first person who ever imagined, and +still more who demonstrated, the true course of the circulation of the +blood in the body; in the second place, he was the first person who +ever understood the mechanism of the heart, and comprehended that its +contraction was the cause of the motion of the blood; and thirdly, he +was the first person who took a just view of the nature of the pulse. +These are the three great contributions which he made to the science of +physiology; and I shall not err in saying--I speak in the presence of +distinguished physiologists, but I am perfectly certain that they will +endorse what I say--that upon that foundation the whole of our +knowledge of the human body, with the exception of the motor apparatus +and the sense organs, has been gradually built up, and that upon that +foundation the whole rests. And not only does scientific physiology +rest upon it, but everything like scientific medicine also rests upon +it. As you know--I hope it is now a matter of popular knowledge--it is +the foundation of all rational speculation about morbid processes; it +is the only key to the rational interpretation of that commonest of all +indications of disease, the state of the pulse; so that, both +theoretically and practically, this discovery, this demonstration of +Harvey's, has had an effect which is absolutely incalculable, and the +consequences of which will accumulate from age to age until they result +in a complete body of physiological science. + +Fig.5.--The junction of the arteries and veins by capillary tubes, +discovered by Malpighi (A.D. 1664). + +I regret that I am unable to pursue this subject much further; but there +is one point I should mention. In Harvey's time, the microscope was +hardly invented. It is quite true that in some of his embryological +researches he speaks of having made use of a hand glass; but that was +the most that he seems to have known anything about, or that was +accessible to him at that day. And so it came about, that, although he +examined the course of the blood in many of the lower animals--watched +the pulsation of the heart in shrimps, and animals of that kind--he +never could put the final coping-stone on his edifice. He did not know +to the day of his death, although quite clear about the fact that the +arteries and the veins do communicate, how it is that they +communicate--how it was that the blood of the arteries passed into the +veins. One is grieved to think that the grand old man should have gone +down to his tomb without the vast satisfaction it would have given to +him to see what the Italian naturalist Malpighi showed only seven years +later, in 1664, when he demonstrated, in a living frog, the actual +passage of the blood from the ultimate ramifications of the arteries +into the veins. But that absolute ocular demonstration of the truth of +the views he had maintained throughout his life it was not granted to +Harvey to see. What he did experience was this: that on the +publication of his doctrines, they were met with the greatest possible +opposition; and I have no doubt savage things were uttered in those old +controversies, and that a great many people said that these new-fangled +doctrines, reducing living processes to mere mechanism, would sap the +foundations of religion and morality. I do not know for certain that +they did, but they said things very like it. The first point was to +show that Harvey's views were absolutely untrue; and not being able to +succeed in that, opponents said they were not new; and not being able +to succeed in that, that they didn't matter. That is the usual course +with all new discoveries. But Harvey troubled himself very little +about these things. He remained perfectly quiet; for although reputed +a hot-tempered man, he never would have anything to do with controversy +if he could help it; and he only replied to one of his antagonists +after twenty years' interval, and then in the most charming spirit of +candour and moderation. But he had the great satisfaction of living to +see his doctrine accepted upon all sides. At the time of his death, +there was not an anatomical school in Europe in which the doctrine of +the circulation of the blood was not taught in the way in which Harvey +had laid it down. In that respect he had a happiness which is granted +to very few men. + +I have said that the other great investigation of Harvey is not one +which can be dealt with to a general audience. It is very complex, and +therefore I must ask you to take my word for it that, although not so +fortunate an investigation, not so entirely accordant with later results +as the doctrine of the circulation; yet that still, this little +treatise of Harvey's has in many directions exerted an influence hardly +less remarkable than that exerted by the Essay upon the Circulation of +the Blood. + +And now let me ask your attention to two or three closing remarks. + +If you look back upon that period of about 100 years which commences +with Harvey's birth--I mean from the year 1578 to 1680 or +thereabouts--I think you will agree with me, that it constitutes one of +the most remarkable epochs in the whole of that thousand years which we +may roughly reckon as constituting the history of Britain. In the +commencement of that period, we may see, if not the setting, at any +rate the declension of that system of personal rule which had existed +under previous sovereigns, and which, after a brief and spasmodic +revival in the time of George the Third, has now sunk, let us hope, +into the limbo of forgotten things. The latter part of that 100 years +saw the dawn of that system of free government which has grown and +flourished, and which, if the men of the present day be the worthy +descendants of Eliott and Pym, and Hampden and Milton, will go on +growing as long as this realm lasts. Within that time, one of the +strangest phenomena which I think I may say any nation has ever +manifested arose to its height and fell--I mean that strange and +altogether marvellous phenomenon, English Puritanism. Within that +time, England had to show statesmen like Burleigh, Strafford, and +Cromwell--I mean men who were real statesmen, and not intriguers, +seeking to make a reputation at the expense of the nation. In the +course of that time, the nation had begun to throw off those swarms of +hardy colonists which, to the benefit of the world--and as I fancy, in +the long run, to the benefit of England herself--have now become the +United States of America; and, during the same epoch, the first +foundations were laid of that Indian Empire which, it may be, future +generations will not look upon as so happy a product of English +enterprise and ingenuity. In that time we had poets such as Spenser, +Shakespere, and Milton; we had a great philosopher, in Hobbes; and we +had a clever talker about philosophy, in Bacon. In the beginning of +the period, Harvey revolutionized the biological sciences, and at the +end of it, Newton was preparing the revolution of the physical sciences. +I know not any period of our history--I doubt if there be any period of +the history of any nation--which has precisely such a record as this to +show for a hundred years. But I do not recall these facts to your +recollection for a mere vainglorious purpose. I myself am of opinion +that the memory of the great men of a nation is one of its most precious +possessions--not because we have any right to plume ourselves upon +their having existed as a matter of national vanity, but because we +have a just and rational ground of expectation that the race which has +brought forth such products as these may, in good time and under +fortunate circumstances, produce the like again. I am one of those +people who do not believe in the natural decay of nations. I believe, +to speak frankly, though perhaps not quite so politely as I could +wish--but I am getting near the end of my lecture--that the whole +theory is a speculation invented by cowards to excuse knaves. My +belief is, that so far as this old English stock is concerned it has in +it as much sap and vitality and power as it had two centuries ago; and +that, with due pruning of rotten branches, and due hoeing up of weeds, +which will grow about the roots, the like products will be yielded +again. The "weeds" to which I refer are mainly three: the first of +them is dishonesty, the second is sentimentality, and the third is +luxury. If William Harvey had been a dishonest man--I mean in the high +sense of the word--a man who failed in the ideal of honesty--he would +have believed what it was easiest to believe--that which he received on +the authority of his predecessors. He would not have felt that his +highest duty was to know of his own knowledge that that which he said +he believed was true, and we should never have had those +investigations, pursued through good report and evil report, which ended +in discoveries so fraught with magnificent results for science and for +man. If Harvey had been a sentimentalist--by which I mean a person of +false pity, a person who has not imagination enough to see that great, +distant evils may be much worse than those which we can picture to +ourselves, because they happen to be immediate and near (for that, I +take it, is the essence of sentimentalism)--if Harvey had been a person +of that kind, he, being one of the kindest men living, would never have +pursued those researches which, as he tells us over and over again, he +was obliged to pursue in order to the ascertainment of those facts which +have turned out to be of such inestimable value to the human race; and +I say, if on such grounds he had failed to do so, he would have failed +in his duty to the human race. The third point is that Harvey was +devoid of care either for wealth, or for riches, or for ambition. The +man found a higher ideal than any of these things in the pursuit of +truth and the benefit of his fellow-men. If we all go and do likewise, +I think there is no fear for the decadence of England. I think that our +children and our successors will find themselves in a commonwealth, +different it may be from that for which Eliott, and Pym, and Hampden +struggled, but one which will be identical in the substance of its +aims--great, worthy, and well to live in. + + + + + +End of The Project Gutenberg Etext of The Circulation of the Blood + diff --git a/old/thx1910.zip b/old/thx1910.zip Binary files differnew file mode 100644 index 0000000..ceef282 --- /dev/null +++ b/old/thx1910.zip |
