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+The Project Gutenberg EBook of Old English Patent Medicines in America, by
+George B. Griffenhagen and James Harvey Young
+
+This eBook is for the use of anyone anywhere at no cost and with
+almost no restrictions whatsoever. You may copy it, give it away or
+re-use it under the terms of the Project Gutenberg License included
+with this eBook or online at www.gutenberg.org
+
+
+Title: Old English Patent Medicines in America
+
+Author: George B. Griffenhagen
+ James Harvey Young
+
+Release Date: October 2, 2009 [EBook #30162]
+
+Language: English
+
+Character set encoding: ASCII
+
+*** START OF THIS PROJECT GUTENBERG EBOOK OLD ENGLISH PATENT MEDICINES ***
+
+
+
+
+Produced by Chris Curnow, Joseph Cooper and the Online
+Distributed Proofreading Team at http://www.pgdp.net
+
+
+
+
+
+
+CONTRIBUTIONS FROM
+THE MUSEUM OF HISTORY AND TECHNOLOGY:
+
+PAPER 10
+
+
+
+
+OLD ENGLISH PATENT MEDICINES IN AMERICA
+
+
+
+_George B. Griffenhagen_ and
+_James Harvey Young_
+
+
+
+
+ORIGINS OF ENGLISH PATENT MEDICINES 156
+
+ENGLISH PATENT MEDICINES COME TO AMERICA 162
+
+COMPLEX FORMULAS AND DISTINCTIVE PACKAGES 166
+
+SOURCE OF SUPPLY SEVERED 168
+
+PHILADELPHIA COLLEGE OF PHARMACY FORMULARY 174
+
+ENGLISH PATENT MEDICINES GO WEST 176
+
+THE PATENT MEDICINES IN THE 20TH CENTURY 179
+
+
+
+
+OLD ENGLISH PATENT MEDICINES IN AMERICA
+
+_By George B. Griffenhagen and James Harvey Young_
+
+
+_Bateman's Pectoral Drops, Godfrey's Cordial, Turlington's Balsam of
+Life, Hooper's Female Pills, and a half-dozen other similar nostrums
+originated in England, mostly during the first half of the 18th
+century. Advertised with extravagant claims, their use soon spread to
+the American Colonies._
+
+_To the busy settler, with little time and small means, these
+ready-made and comparatively inexpensive "remedies" appealed as a
+solution to problems of medical and pharmaceutical aid. Their
+popularity brought forth a host of American imitations and made an
+impression not soon forgotten or discarded._
+
+THE AUTHORS: _George B. Griffenhagen, formerly curator of medical
+sciences in the Smithsonian Institution's U.S. National Museum, is now
+Director of Communications for the American Pharmaceutical Association.
+James Harvey Young is professor of history at Emory University. Some of
+the material cited in the paper was found by him while he held a
+fellowship from the Fund for the Advancement of Education, in 1954-55,
+and grants-in-aid from the Social Science Research Council and Emory
+University, in 1956-57._
+
+
+
+
+In 1824 there issued from the press in Philadelphia a 12-page pamphlet
+bearing the title, _Formulae for the preparation of eight patent
+medicines, adopted by the Philadelphia College of Pharmacy_. The
+College was the first professional pharmaceutical organization
+established in America, having been founded in 1821, and this small
+publication was its first venture of any general importance. Viewed
+from the perspective of the mid-20th century, it may seem strange if
+not shocking that the maiden effort of such a college should be
+publicizing formulas for nostrums. Adding to the novelty is the fact
+that all eight of these patent medicines, with which the Philadelphians
+concerned themselves half a century after American independence, were
+of English origin.
+
+Hooper's Female Pills, Anderson's Scots Pills, Bateman's Pectoral
+Drops, Godfrey's Cordial, Dalby's Carminative, Turlington's Balsam of
+Life, Steer's Opodeldoc, British Oil--in this order do the names appear
+in the Philadelphia pamphlet--all were products of British therapeutic
+ingenuity. Across the Atlantic Ocean and on American soil these eight
+and other old English patent medicines, as of the year when the 12-page
+pamphlet was printed, had both a past and a future.
+
+
+Origin of English Patent Medicines
+
+When the Philadelphia pharmacists began their study, the eight English
+patent medicines were from half a century to two centuries old.[1] The
+most ancient was Anderson's Scots Pills, a product of the 1630's, and
+the most recent was probably Dalby's Carminative, which appeared upon
+the scene in the 1780's. Some aspects of the origin and development of
+these and similar English proprietaries have been treated, but a more
+thorough search of the sources and a more integrated and interpretive
+recounting of the story would be a worthy undertaking. Here merely an
+introduction can be given to the cast of characters prior to their
+entrances upon the American stage.
+
+ [1] Unless otherwise indicated, the early English history of
+ these patent medicines has been obtained from the following
+ sources: "Proprietaries of other days," _Chemist and Druggist_,
+ June 25, 1927, vol. 106, pp. 831-840; C. J. S. Thompson, _The
+ mystery and art of the apothecary_, London, 1929; C. J. S.
+ Thompson, _Quacks of old London_, London, 1928; and A. C.
+ Wootton, _Chronicles of pharmacy_, London, 1910, 2 vols.
+
+The inventor of Anderson's Scots Pills was fittingly enough a Scot
+named Patrick Anderson, who claimed to be physician to King Charles I.
+In one of his books, published in 1635, Anderson extolled in Latin the
+merits of the Grana Angelica, a pill the formula for which he said he
+had learned in Venice. Before he died, Anderson imparted the secret to
+his daughter Katherine, and in 1686 she in turn conveyed the secret to
+an Edinburgh physician named Thomas Weir. The next year Weir persuaded
+James II to grant him letters patent for the pills. Whether he did
+this to protect himself against competition that already had begun,
+or whether the patenting gave a cue to those always ready to cut
+themselves in on a good thing, cannot be said for sure. The last years
+of the 17th century, at any rate, saw the commencement of a spirited
+rivalry among various makers of Anderson's Scots Pills that was long to
+continue. One of them was Mrs. Isabella Inglish, an enterprising woman
+who sealed her pill boxes in black wax bearing a lion rampant, three
+mallets argent, and the bust of Dr. Anderson. Another was a man named
+Gray who sealed his boxes in red wax with his coat of arms and a motto
+strangely chosen for a medicine, "Remember you must die."
+
+[Illustration: Figure 1.--THE PHILADELPHIA COLLEGE OF PHARMACY in 1824
+set forth in this pamphlet formulas for eight old English patent
+medicines. (_Courtesy, Philadelphia College of Pharmacy and Science,
+Philadelphia, Pennsylvania._)]
+
+Competition already had begun when Godfrey's Cordial appeared in the
+record in a London newspaper advertisement during December 1721. John
+Fisher of Hertfordshire, "Physician and Chymist," claimed to have
+gotten the true formula from its originator, the late Dr. Thomas
+Godfrey of the same county. But there is an alternate explanation.
+Perhaps the Cordial had its origin in the apothecary shop established
+about 1660 by Ambroise (Hanckowitz) Godfrey in Southampton Street,
+London.[2] According to a handbill issued during the late 17th century,
+Ambroise Godfrey prepared "Good Cordials as Royal English Drops."
+
+ [2] "How the patent medicine industry came into its own,"
+ _American Druggist_, October 1933, vol. 88, pp. 84-87, 232, 234,
+ 236, 238.
+
+[Illustration: Figure 2.--ANTHONY DAFFY EXTOLLED THE VIRTUES OF HIS
+ELIXIR SALUTIS in this pamphlet, published in London in 1673.
+(_Courtesy, British Museum._)]
+
+With respect to his rivals, the 18th-century Hertfordshire vendor of
+the Cordial warned in the _Weekly Journal_ (London), December 23, 1721:
+"I do advise all Persons, for their own Safety, not to meddle with the
+said Cordial prepared by illiterate and ignorant Persons, as Bakers,
+Malsters, [sic] and Goldsmiths, that shall pretend to make it, it being
+beyond their reach; so that by their Covetousness and Pretensions, many
+Men, Women, and especially Infants, may fall as Victims, whose Slain
+may exceed Herod's Cruelty...."
+
+In 1726 King George I granted a patent for the making and selling of
+Dr. Bateman's Pectoral Drops. The patent was given not to a doctor, but
+to a business man named Benjamin Okell. In the words of the patent,[3]
+Okell is lauded for having "found out and brought to Perfection, a new
+Chymicall Preparacion and Medicine..., working chiefly by Moderate
+Sweat and Urine, exceeding all other Medicines yet found out for the
+Rheumatism, which is highly useful under the Afflictions of the Stone,
+Gravell, Pains, Agues, and Hysterias...." What the chemicals
+constituting his remedy were, the patentee did not vouchsafe to reveal.
+
+ [3] Benjamin Okell, "Pectoral drops for rheumatism, gravel,
+ etc.," British patent 483, March 31, 1726.
+
+The practice of patenting had begun in royal prerogative. Long
+accustomed to granting monopoly privileges for the development of new
+industries, the discovery of new lands, and the enrichment of court
+favorites, various monarchs in 17th-century Europe had given letters
+patent to proprietors of medical remedies which had gained popular
+acclaim. In France and the German States, this practice continued well
+through the 18th century. In England, where representative government
+had progressed at the expense of the personal prerogative of the
+sovereign, Parliament passed a law in 1624 aimed at curbing arbitrary
+actions like those of James I and Charles I. The statute declared all
+monopolies void except those extended to the first inventor of a new
+process of manufacture. To such pioneers the king could grant his
+letters patent bestowing monopoly privileges for a period of 14 years.
+That the machinery set up by this law did not completely curb the
+independence of English sovereigns in the medical realm is indicated by
+the favor extended Dr. Weir, who successfully sought from James II a
+privileged position for Anderson's Scots Pills. This kingly grant is
+not included in the regular list, and the Glorious Revolution of 1688
+brought an end to such an exercise of royal power without consent of
+Parliament. A list of patents in the medical field later published by
+the Commissioners of Patents[4] includes only six issued during the
+17th century, four for baths and devices, one for an improved method of
+preparing alum, and one for making epsom salts. The first patent for a
+compound medicine was granted in 1711, and only two other proprietors
+preceded Benjamin Okell in seeking this particular legal form of
+protection and promotion.
+
+As early as 1721, Bateman's Pectoral Drops were being regularly
+advertised in the _London Mercury_. The advertisements announced: "Dr.
+Bateman's Pectoral DROPS published at the Request of several Persons of
+Distinction from both Universities...." The Drops, priced at "1 s. a
+Bottle," were "Sold Wholesale and Retail at the Printing-house and
+Picture Warehouse in Bow Churchyard," and likewise "in most Cities and
+celebrated Towns in Great Britain." "Each Bottle Seal'd with the Boar's
+Head." So stated the advertisement, which itself contained a crude cut
+of this Boar's Head seal.[5] Elsewhere in this issue of the _Mercury_,
+we learn that John Cluer, printer, was the proprietor of the Bow
+Churchyard Warehouse. This same John Cluer, along with William Dicey
+and Robert Raikes, were named in the 1726 patent as "the Persons
+concerned with the said Inventor," Benjamin Okell, who, with him,
+should "enjoy the sole Benefit of the said Medicine." It was this
+partnership which was to find the field of nostrum promotion especially
+congenial and which was to play an important transatlantic role. Soon
+after securing their patent, the proprietors undertook to inform their
+countrymen about the remedy by issuing _A short treatise of the virtues
+of Dr. Bateman's Pectoral Drops_.[6]
+
+ [4] British Patent Office, _Patents for inventions: abridgements
+ of specifications relating to medicine, surgery, and dentistry,
+ 1620-1866_, London, 1872.
+
+ [5] _London Mercury_, London, August 19-26, 1721.
+
+ [6] _A short treatise of the virtues of Dr. Bateman's Pectoral
+ Drops_, New York, 1731. A 36-page pamphlet preserved in the
+ Library of the New York Academy of Medicine. This is an American
+ reprint of an English original, date unknown.
+
+It was the 18th century, and the essay was in fashion. The proprietors
+prepared a didactic introduction to their treatise, phrased in long and
+flowery sentences, in which modesty was not the governing tone. The
+arguments ran like this: that the "Universal Good of Mankind" should be
+the aim of "every private member"; that nothing is so conducive to this
+general welfare as "HEALTH"; that no hazards to health are more direful
+than diseases such as "the Gout; the Rheumatism; the Stone; the
+Jaundice," etc., etc.; that countless men and women have succumbed to
+such afflictions either because they received no treatment or suffered
+wrong treatment at "the Hands of the Learned"; that no medicine is so
+sure a cure as that inexpensive remedy discovered as a result of great
+"Piety, Learning and Industry" by one "inspir'd with the Love of his
+Country, and the Good of Mankind," to wit. "Dr. BATEMAN'S Pectoral
+Drops."
+
+Then followed seven chapters treating the multitude of illnesses for
+which the Drops were a specific. Finally, the pamphlet cited "some few,
+out of the many thousands of Certificates of Cures effected by these
+DROPS...." Even so early was the testimonial deemed a powerful
+persuader.
+
+No more could Okell, Cluer, Dicey, and Raikes escape competition than
+could the proprietors of other successful nostrums. In 1755 they went
+to court and won a suit for the infringement of their patent, but the
+damages amounted to only a shilling. Even after the patent expired, the
+tide of publicity flowed on.[7]
+
+ [7] A broadside, issued in London, _ca._ 1750, advertising "Dr.
+ Bateman's Drops," is preserved in the Warshaw Collection of
+ Business Americana, New York. Later reprints of this same
+ broadside are preserved in the private collection of Samuel Aker,
+ Albany, New York, and in the Smithsonian Institution.
+
+Competition was also lively in the 1740's among some half a dozen
+proprietors marketing a form of crude petroleum under the name of
+British Oil. Early in the decade Michael and Thomas Betton were granted
+a patent for "An Oyl extracted from a Flinty Rock for the Cure of
+Rheumatick and Scorbutick and other Cases." The source of the oil,
+according to their specifications, was rock lying just above the coal
+in mines, and this rock was pulverized and heated in a furnace to
+extract all the precious healing oil.[8] This Betton patent aroused one
+of their rivals, Edmund Darby & Co. of Coalbrook-Dale in Shropshire.
+Darby asserted that it was presumptuous of the Bettons to call their
+British oyl a new invention.[9] For over a century Darby and his
+predecessors had been marketing this self-same product, and it had
+proved to be "the one and only unrivall'd and most efficacious Remedy
+ever yet discovered, against the whole force of Diseases and Accidents
+that await Mankind...." For the Bettons to appropriate the process and
+patent it--and even to claim in their advertising cures which really
+had been wrought by the Darby product--was scandalous. Worse than that,
+said Darby, it was illegal, for in 1693 William III had granted a
+patent to "Martin Eele and two others at his Nomination for making the
+same Sort of Oyl from the same Sort of Materials." Evidence to
+substantiate his belief in the Betton perfidy was presented by Darby to
+George II, who had the matter duly investigated.[10] Being persuaded
+that Darby was right, the king and his councillors, in 1745, vacated
+the Betton patent. This victory seems not to have boomed the Darby
+interests, and this defeat seems not to have ruined the Bettons. During
+the succeeding century, the Betton patent was published and republished
+in advertising, just as if it had never fallen afoul the law. From
+their battles with the Oil from Coalbrook-Dale and other British Oils
+marketed by other proprietors, the Bettons emerged triumphant. In the
+years to come, patent or no, the Bettons British Oil was to dominate
+the field.
+
+ [8] Michael and Thomas Betton, "Oil for the cure of rheumatic and
+ scorbutic affections," British patent 587, August 14, 1742.
+
+ [9] Edmund Darby & Co., _Directions for taking inwardly and using
+ outwardly the company's true genuine and original British Oil;
+ prepared by Edmund Darby & Co. at Coalbrook-Dale, Shropshire_,
+ ca. 1745. An 8-page pamphlet preserved in the Library of the
+ College of Physicians, Philadelphia, Pennsylvania.
+
+ [10] _London Gazette_, London, March 1, 1745.
+
+The year after the Bettons had secured their patent, another was
+granted to John Hooper of Reading for the manufacture of "Female Pills"
+bearing his name.[11] Hooper was an apothecary, a man-midwife, and a
+shrewd fellow. This was the period in which the British Government was
+increasing its efforts to require the patentee to furnish precise
+specifications with his application.[12] When Hooper was called upon to
+tell what was in his pills and how they were made, he replied by
+asserting that they were composed "Of the best purging stomatick and
+anti-hysterick ingredients," which were formed into pills the size of a
+small pea. This satisfied the royal agents and Hooper went on about his
+business. In an advertisement of the same year, he was able to cite as
+a witness to his patent the name of the Archbishop of Canterbury.[13]
+
+ [11] John Hooper, "Pills," British patent 592, July 21, 1743.
+
+ [12] E. Burke Inlow, _The patent grant_, Baltimore, 1950, p. 33.
+
+ [13] _Daily Advertiser_, London, September 23, 1743.
+
+Much less taciturn than Hooper about the composition of his nostrum was
+Robert Turlington, who secured a patent in 1744 for "A specifick
+balsam, called the balsam of life."[14] The Balsam contained no less
+than 27 ingredients, and in his patent specifications Turlington
+asserted that it would cure kidney and bladder stones, cholic, and
+inward weakness. He shortly issued a 46-page pamphlet in which he
+greatly expanded the list.[15] In this appeal to 18th-century
+sensibilities, Turlington asserted that the "Author of Nature" has
+provided "a Remedy for every Malady." To find them, "Men of Learning
+and Genius" have "ransack'd" the "Animal, Mineral and Vegetable World."
+His own search had led Turlington to the Balsam, "a perfect Friend to
+Nature, which it strengthens and corroborates when weak and declining,
+vivifies and enlivens the Spirits, mixes with the Juices and Fluids of
+the Body and gently infuses its kindly Influence into those Parts that
+are most in Disorder."
+
+ [14] Robert Turlington, "A Specifick balsam, called the balsam of
+ life," British patent 596, January 18, 1744.
+
+ [15] Robert Turlington, _Turlington's Balsam of Life_, ca. 1747.
+ A 46-page pamphlet preserved in the Folger Shakespeare Library,
+ Washington, D.C.
+
+[Illustration: Figure 3.--LABEL FOR STOUGHTON'S ELIXIR as manufactured
+by Dr. Jos. Frye of Salem, Massachusetts. (_Courtesy, Essex Institute,
+Salem, Massachusetts._)]
+
+Testimonials from those who had felt the kindly influence took up most
+of the space in Turlington's pamphlet. In these grateful
+acknowledgments to the potency of the patent medicine, the list of
+illnesses cured stretched far beyond the handful named in the patent
+specifications. Just as for Bateman's Pectoral Drops and the Darby
+brand of British Oil, workers of many occupations solemnly swore that
+they had received benefit. Most of them were humble people--a porter, a
+carpenter, the wife of a gardener, a blanket-weaver, a gunner's mate, a
+butcher, a hostler, a bodice-maker. Some bore a status of greater
+distinction: there were a "Mathematical Instrument-Maker" and the
+doorkeeper of the East India Company. All were jubilant at their
+restored good health.
+
+The Balsam's well-nigh sovereign power could not protect it from one
+ailment of the times, competition. Various preparations of similar
+composition, like Friar's Balsam, already were on the market, but
+before long even the Turlington name was trespassed upon, and the
+inventor's niece was forced to advertise that she alone had the true
+formula and that any person who took a dose of the spurious imitations
+being offered did so at great hazard to his life.
+
+A quarter of a century after the patenting of the Balsam, there
+appeared for sale to British ailing a remedy called Dr. Steer's
+Celebrated Opodeldoc. Dr. Steer is a shadowy rider of a vigorous
+steed, for although the doctor has left but a faint personal impact
+upon the historical record, Opodeldoc has pranced through medical
+history since the time of Paracelsus. This 16th-century continental
+chemist-physician, who introduced many mineral remedies into the
+materia medica, had coined the word "opodeldoc" to apply to various
+medical plasters. In the two ensuing centuries the meaning had
+changed, and the _Pharmacopoeia Edinburgensis_ of 1722 employed the
+term to designate soap liniment. It is presumed that Dr. Steer
+appropriated the Edinburgh formula, added ammonia, and marketed his
+proprietary version. In 1780, a London paper carried an advertisement
+listing the difficulties for which the Opodeldoc was a "speedy and
+certain cure." These included bruises, sprains, burns, cuts,
+chillblains, and headaches. Furthermore, the remedy had been "found
+of infinite Use in hot Climates for the Bite of venomous
+Insects."[16] Dr. Steer seems not to have secured a patent for his
+slightly modified version of an official preparation. He died in
+1781, but Opodeldoc, indeed Steer's Opodeldoc, went marching on.[17]
+
+ [16] _Daily Advertiser_, London, February 18, 1780.
+
+ [17] Broadsides, _ca._ 1810-1822, advertising "Steer's Chemical
+ Opodeldoc, for bruises, sprains, rheumatism, etc., etc.," are
+ preserved in the American Antiquarian Society, Worcester,
+ Massachusetts; the Library of the New York Academy of Medicine;
+ and the Warshaw Collection of Business Americana, New York.
+
+About the same time that Dr. Steer began advertising, newspaper
+promotion was launched in behalf of another remedy, called Dalby's
+Carminative. The inventor, J. Dalby, was a London apothecary, and his
+unpatented concoction was designed to cure "Disorders of the Bowels."
+One early advertisement[18] added details: "This Medicine, which is
+founded on just Medical Principles, has been long established as a most
+safe and effectual Remedy, generally affording immediate Relief in the
+Wind, Cholocks [_sic_], Convulsions, Purgings, and all those fatal
+Disorders in the Bowels of Infants, which carry off so great a number
+under the age of 2 years. It is also equally efficacious in gouty Pains
+in the Intestines, in Fluxes, and in the cholicky Complaints of grown
+Persons, so usual at this Season of the Year." Dalby, like Steer,
+failed long to survive the appearance of his medicine on the market.
+
+ [18] _Daily Advertiser_, London, January 4, 1781.
+
+Such were the origins of the eight remedies which the Philadelphia
+pharmacists were to take account of in 1824. Besides these eight, two
+other patent medicines, both elixirs, were destined for roles of such
+special interest that a brief look at their English background is
+warranted.
+
+One of them, Daffy's Elixir, was the invention of a clergyman, Rev.
+Thomas Daffy soon after 1650. Daffy had his troubles during that
+troubled century, losing a pastorate because he offended a powerful
+Countess. When the rector first sought to minister unto men's bodies as
+well as to their souls is not known. According to a pamphlet issued in
+1673, after the Rev. Daffy had passed from the scene, the formula had
+been "found out by the Providence of the Almighty." By this time a
+London kinsman of the inventor, named Anthony Daffy, was vending the
+remedy. The full name of the medicine, according to the pamphlet's
+title, was "Elixir Salutis: The Choice Drink of Health, or
+Health-Bringing Drink," and among the ailments for which it was
+effective were gout, the stone, colic, "ptissick," scurvy, dropsy,
+rickets, consumption, and "languishing and melancholly."
+
+The Elixir Salutis proved immensely popular. It was too much to expect
+that Anthony should hold the field uncontested; in the 1673 pamphlet
+one false fabricator was called by name, and in 1680 Anthony advertised
+to warn against "diverse Persons" who were not only counterfeiting the
+medicine but spreading the malicious rumor that Anthony was dead. Early
+in the new century, Catherine, the daughter of the original Rev. Daffy,
+insisted that she as well as her cousin Anthony had received the
+valuable formula. But it was Anthony's line that was to prove the more
+persistent. In 1743, one Susannah Daffy advertised the "Original and
+Famous Elixir," asserting that she had a brother Anthony who also knew
+the secret.[19] This Anthony died in 1750 and willed the formula to his
+niece. But there were others outside the family who long had been
+making and selling the medicine. For example, the Bow Churchyard
+Warehouse advertised Daffy's Elixir in the _London Mercury_ during
+1721. Without hiding the fact that others were also compounding this
+"safe and pleasant Cordial ... well-known throughout England, where it
+has been in great Use these 50 Years," the advertisement concluded:
+"Those who make tryalof That sold at this [Bow Churchyard] Warehouse
+will never buy anywhere else."[20]
+
+ [19] _Ibid._, September 7, 1743.
+
+ [20] _London Mercury_, London, August 19-26, 1721.
+
+Although once lauded by a physician to King Charles II, Daffy's Elixir
+was never patented. The Elixir invented by Richard Stoughton was, in
+1712, the second compound medicine to be granted a patent in
+England.[21] Stoughton was an apothecary who had a shop at the Sign of
+the Unicorn in Southwark, Surrey. It was evidently competition, the
+constant bane of the medicine proprietor's life, that drove him to seek
+governmental protection. In his specifications he asserted that he had
+been making his medical mixture for over twenty years. Stoughton was
+less precise about his formula; indeed, he gave none, but was generous
+in indicating the remedy's name: "Stoughton's Elixir Magnum Stomachii,
+or the Great Cordial Elixir, otherwise called the Stomatick Tincture or
+Bitter Drops." In a handbill, the apothecary did tip his hand to the
+extent of asserting that his Elixir contained 22 ingredients, but added
+that nobody but himself knew what they were. The dosage was generous,
+50 to 60 drops "in a glass of Spring water, Beer, Ale, Mum, Canary,
+White wine, with or without sugar, and a dram of brandy as often as you
+please." This, it was said, would cure any stomach ailment
+whatever.[22]
+
+ [21] Richard Stoughton, "Restorative cordial and medicine,"
+ British patent 390, 1712.
+
+ [22] From a broadside, _ca._ 1750, advertising "Dr. Stoughton's
+ Elixir Magnum Stomachum," preserved in the American Antiquarian
+ Society, Worcester, Mass.
+
+The inventor died in 1726, and his passing precipitated a perfect fury
+of competitive advertising. As in the case of Daffy's, there was a
+family feud. A son of Stoughton and the widow of another son argued
+vituperously in print, each claiming sole possession of Richard's
+complicated secret, and each terming the other a scoundrel. The
+daughter-in-law accused the son of financial chicanery, and the son
+condemned the daughter-in-law for having run through two husbands and
+for desperately wanting a third. In the midst of this running battle, a
+third party entered the lists as maker of the Elixir. She was no
+Stoughton--though a widow--and her quaint claim for the public's
+consideration lay in this, that her late husband had infringed
+Stoughton's patent until restrained by the Lord Chancellor.
+
+These ten medicines--Stoughton's and Daffy's Elixirs and the eight
+which the Philadelphia pharmacists were later to select--were by no
+means the only packaged remedies available to the 18th-century
+Englishman who resorted to self-dosage for his ills. Between 1711, when
+the first patent was granted for a compound medicine, and 1776, some 75
+items were patented in the medical field.[23] And, along with Godfrey's
+Cordial and Daffy's Elixir, there were scores of other remedies for
+which no patents had been given. A list of nostrums published in _The
+Gentleman's Magazine_ in 1748 totaled 202, and it was admittedly
+incomplete.[24] The proprietor with a patent might do his utmost to
+keep this badge of governmental sanction before the public, but the
+distinction was not great enough in such a crowded field to make things
+clear. The casual buyer could not keep track of which electuary had
+been granted a patent and which lozenge had not. They were all bottles
+and boxes upon the shelf. In use they served the same purpose. One term
+arose in common speech to apply to both, and it was "patent medicine."
+
+ [23] British Patent Office, _op. cit._ (see footnote 4).
+
+ [24] Poplicola, "Pharmacopoeia empirica or the list of nostrums
+ and empirics," _The Gentleman's Magazine_, 1748, vol. 18, pp.
+ 346-350.
+
+
+English Patent Medicines Come to America
+
+When the first English packaged medicine, patented or unpatented, came
+to the New World, cannot be told. Some 17th-century prospective
+colonist, setting forth to face the hazards of life in Jamestown or
+Baltimore or Boston, must have packed a box of Anderson's Scots Pills
+or a bottle of Daffy's Elixir to bring along, but no record to
+substantiate such an incident has been encountered. It would seem that
+the use of English packaged remedies in America was most infrequent
+before 1700. Samuel Lee, answering questions posed from England in 1690
+about the status of medicine and pharmacy in Massachusetts, mentions no
+patent medicines.[25] Neither does the 1698 account book of the Salem
+apothecary, Bartholomew Brown.[26]
+
+ [25] George L. Kittredge, "Letters to Samuel Lee and Samuel
+ Sewall relating to New England and the Indians," _Colonial
+ Society of Massachusetts, Transactions_, 1913, vol. 14, pp.
+ 142-186.
+
+ [26] Bartholomew Brown, Apothecary day book, Salem [1698];
+ manuscript original preserved in the Library of the Essex
+ Institute, Salem, Massachusetts.
+
+[Illustration: Figure 4.--PATRICK ANDERSON, M.D., from a box of
+Anderson's Scots Pills. From Wootton's _Chronicles of pharmacy_,
+London, 1910. (_Smithsonian photo 44286-C._)]
+
+In the _Boston News-Letter_ for October 4, 1708, Nicholas Boone, at the
+Sign of the Bible, near the corner, of School-House-Lane, advertised
+for sale: "DAFFY'S Elixir Salutis, very good, at four shillings and
+sixpence _per_ half pint Bottle." This may well be the first printed
+reference in America to an English patent medicine, and it certainly is
+the first newspaper advertisement for a nostrum. Preceding the
+_News-Letter_ in colonial America, there had been only one paper, the
+_Publick Occurrences Both Foreign and Domestic_.[27] This journal had
+lasted but a single issue. Then its printer had returned to England,
+where he took up the career of a patent medicine promoter, vending "the
+only Angelical Pills against all Vapours, Hysterick Fits." The
+_News-Letter_ had begun with the issue of April 27, 1704, about 4 years
+before Boone's advertisement for Daffy's remedy made its appearance,
+but during that time, only one advertisement for anything at all in the
+medical field had appeared, and that was for a home-remedy book, _The
+English physician_, by Nicholas Culpeper, Doctor of Physick.[28] This
+volume was also for sale at Boone's shop.
+
+ [27] Frank L. Mott, _American journalism_, New York, 1941, pp.
+ 9-10.
+
+ [28] _Boston News-Letter_, Boston, February 9, 1708.
+
+Patent-medicine advertising in the _News-Letter_ prior to 1750 was
+infrequent. Apothecary Zabdiel Boylston, who a decade later was to earn
+a role of esteem in medical history by introducing the inoculation for
+smallpox, announced in 1711 that he would sell "the true Lockyers
+Pills."[29] This was an unpatented remedy first concocted half a
+century earlier by a "licensed physitian" in London. The next year
+Boylston repeated this appeal,[30] and in the same advertisement listed
+other wares of the same type. He had two varieties, Golden and Plain,
+of the Spirit of Scurvy-Grass; he had "The Bitter Stomach Drops," worm
+potions for children; and a wonderful multipurpose nostrum, "the Royal
+Honey Water, an Excellent Perfume, good against Deafness, and to Make
+Hair grow...." The antecedents of this regal liquid are unknown.
+Boylston also announced for sale "The Best [Daffy's] Elixir Salutis in
+Bottles, or by the Ounce." This is a provocative listing. It may mean
+merely that the apothecary would break a bottle to sell a dose of the
+Elixir, which was often the custom. But it also may suggest that
+Boylston was making the Elixir himself, or was having it prepared by a
+journeyman. This latter interpretation would place Boylston well at the
+head of a long parade of American imitators of the old English patent
+medicines.
+
+ [29] _Ibid._, March 12, 1711.
+
+ [30] _Ibid._, March 24, 1712.
+
+Other such shipments of the packaged English remedies may have come to
+New England on the latest ships from London during the next several
+decades, but they got scant play in the advertising columns of the
+small 4-page _Boston News-Letter_. Another reference to "Doctor Anthony
+Daffey's Original Elixer Salutis" occurs in 1720.[31] Ten years later,
+Stoughton's Drops were announced for sale "by Public Vendue," along
+with feather beds, looking glasses, and leather breeches.[32] Nearly a
+decade more was to pass before Bateman's Pectoral Drops showed up in
+the midst of another general list, including cheese, and shoes, and
+stays.[33] Not until 1748 did an advertisement appear in which several
+of the old English nostrums rubbed shoulders with each other.[34] Then
+Silvester Gardiner, at the Sign of the Unicorn and Mortar, asserted
+that "by appointment of the Patentee" he was enabled to sell "Genuine
+British Oyl, _Bateman's_ Pectoral Drops, and _Hooper's_ Female Pills,
+and the True _Lockyer's_ Pills."
+
+ [31] _Ibid._, November 14, 1720.
+
+ [32] _Ibid._, March 12, 1730.
+
+ [33] _Ibid._, January 4, 1739.
+
+ [34] _Ibid._, November 14, 1748.
+
+Although nearly a century old, Anderson's Scots Pills were not cited
+for sale in the pages of the _Boston News-Letter_ until August 23,
+1750, two months after the much more recent Turlington's Balsam of Life
+first put in its appearance.[35] During the same year, the British
+confusion over British Oil was reflected in America. Boden's and
+Darby's variety preceded the Betton brand into the _News-Letter_ pages
+by a fortnight.[36] It was the latter, however, which was to win the
+day in Boston, for almost all subsequent advertising specified the
+Betton Oil. Godfrey's Cordial was first mentioned in 1761.[37] Thus, of
+the ten old English patent medicines which are the focus of the present
+study, eight had been advertised in the _Boston News-Letter_. The other
+two, Steer's Opodeldoc and Dalby's Carminative, did not reach the
+market before this colonial journal fell prey to the heightening
+tensions of early 1776.
+
+ [35] _Ibid._, June 7, 1750.
+
+ [36] _Ibid._, May 24, 1750.
+
+ [37] _Ibid._, December 31, 1761.
+
+By the 1750's, the names of several old English nostrums were appearing
+fairly frequently in the advertising of colonial apothecaries, not only
+in Boston but in other colonial towns. In Williamsburg, for example, a
+steady increase occurs in the number of references and the length of
+the lists of the English patent medicines advertised in the _Virginia
+Gazette_ from their first mention into the early 1760's.[38] This
+journal--which later had competing issues by different editors--was
+launched in 1736, and the next year George Gilmer advised customers
+that, in addition to "all manner of Chymical and Galenical Medicines,"
+he could furnish, at his old shop near the Governor's, "Bateman's
+Drops, Squires Elixir, Anderson's Pills."[39] The other remedies
+appeared in due time, Stoughton's and Daffy's Elixirs in 1745,
+Turlington's Balsam in 1746, Godfrey's Cordial in 1751, Hooper's Pills
+in 1752, and Betton's British Oil in 1770.
+
+ [38] Lester J. Cappon and Stella F. Duff, _Virginia Gazette
+ index, 1736-1780_, Williamsburg, 1950, 2 vols.
+
+ [39] _Virginia Gazette_, Williamsburg, May 27, 1737.
+
+A spot check of newspapers in Philadelphia and New York reveals a
+pattern quite similar. Residents of the middle colonies, like those to
+the north and the south, could buy the basic English brands, and it was
+during the 1750's that the notices of freshly-arrived supplies ceased
+to be rare in advertising columns and became a frequent occurrence.
+Thomas Preston, for example, announced to residents of Philadelphia in
+1768 that he had just received a supply of Anderson's, Hooper's,
+Bateman's, Betton's, Daffy's, Stoughton's, Turlington's, and Godfrey's
+remedies.[40] Not only were these medicines for sale at apothecary
+shops, but they were sold by postmasters, goldsmiths, grocers, hair
+dressers, tailors, printers, booksellers, cork cutters, the post-rider
+between Philadelphia and Williamsburg, and by many colonial American
+physicians.
+
+ [40] _Pennsylvania Gazette_, Philadelphia, December 1, 1768.
+
+It is a matter for comment that American newspaper advertising of the
+English packaged medicines was singularly drab. In the mother country,
+the proprietors or their heirs were faced with vigorous competition. It
+behooved them to sharpen up their adjectives and reach for their
+vitriol. In America the apothecary or merchant had no proprietary
+interest in any of the different brands of the imported medicines which
+were sold. Moreover, there was probably no great surplus of supply over
+demand in America as in Britain, so the task of selling the stock on
+hand was less difficult and required less vigorous promotion. Also,
+advertising space in the few American weeklies was more at a premium
+than in the more frequent and numerous English journals. With rare
+exceptions, therefore, the old English patent medicines were merely
+mentioned by name in American advertising. Seldom did one receive the
+individual attention accorded by Samuel Emlen to Godfrey's Cordial in
+Benjamin Franklin's _Pennsylvania Gazette_ for June 26, 1732. The ad
+ran like this:
+
+ "Dr. Godfrey's General Cordial. So universally approved of for the
+ Cholick, and all Manners cf Pains in the Bowels, Fluxes, Fevers,
+ Small-Pox, Measles, Rheumatism, Coughs, Colds, and Restlessness in
+ Men, Women, and Children; and particularly for several Ailments
+ incident to Child-bearing Women, and Relief of young Children in
+ breeding their Teeth."
+
+[Illustration: Figure 5.--PAMPHLET, DATED 1731, ON BEHALF OF BATEMAN'S
+PECTORAL DROPS. It was published by John Peter Zenger in New York.
+Original preserved in the New York Academy of Medicine Library.
+(_Smithsonian photo 44286-D._)]
+
+Emlen's venturesomeness may have lain in the fact that he was not only
+a retailer, but also an agent for the British manufacturer, for he
+cited the names of those who sold Godfrey's Cordial in nearby towns.
+Even at that, this appeal, consisting merely of a list of illnesses,
+lacked the cleverness of contemporary English nostrum advertising. In
+the whole span of the _Boston News-Letter_, beginning in 1704, it was
+not until 1763 that a bookstore pulled out the stops with half a column
+of lively prose in behalf of Dr. Hill's four unpatented nostrums.[41]
+It seems a safe assumption that not only the medicines but the verbiage
+were imported from London, where Dr. Hill had been at work endeavoring
+to restore a Greek secret which "converts a Glass of Water into the
+Nature and Quality of Asses Milk, with the Balsamick Addition...."
+
+ [41] _Boston News-Letter_, Boston, November 24, 1763.
+
+The infrequency of extended fanciful promotion in behalf of the old
+English nostrums in American newspaper advertising may have been
+compensated for to some degree in broadside and pamphlet. A critic of
+the medical scene in New York in the early 1750's asserted that
+physicians used patent medicines which they learned about from "London
+quack bills." This doctor complained, these were often their only
+reading matter.[42] Such a judgment may be too severe. Certainly it is
+difficult to validate today. Such pamphlets and broadsides do appear in
+American archival collections. The Historical Society of Pennsylvania
+contains a 2-page Turlington broadside,[43] while the Folger
+Shakespeare Library in Washington has an earlier 46-page Turlington
+pamphlet with testimonials reaching out toward America.[44] One such
+certificate came from "a sailor before the mast, on board the ship
+Britannia in the New York trade," and another cited a woman living in
+Philadelphia who gave thanks for the cure of her dropsy.
+
+ [42] James J. Walsh, _History of the Medical Society of the State
+ of New York_, New York, 1907.
+
+ [43] Robert Turlington, "Turlington's Balsam of Life," 1755-1757.
+ A later reprint of this same circular is preserved in the Warshaw
+ Collection of Business Americana.
+
+ [44] _Turlington's Balsam of Life_ (see footnote 15).
+
+A broadside in the Warshaw Collection touting Bateman's Drops noted
+that "extraordinary demands have been made for Maryland, New-York,
+Jamaica, etc. where their virtues have been truely experienced with the
+greatest satisfaction."[45] That such promotional items are extremely
+rare does not mean they were not abundant in the mid-18th century, for
+this type of printed matter, then as now, was likely to be looked at
+and thrown away. A certain amount of nostrum literature was undoubtedly
+imported from Britain. For example, in 1753 apothecary James Carter of
+Williamsburg ordered from England "3 Quire Stoughton's Directions"
+along with "1/2 Groce Stoughton Vials."[46] These broadsides or
+circulars served a twofold purpose. Not only did they promote the
+medicine, but they actually served as the labels for the bottles. Early
+packages of these patent medicines which have been discovered indicate
+that paper labels were seldom applied to the glass bottles; instead,
+the bottle was tightly wrapped and sealed in one of these broadsides.
+
+ [45] "Dr. Bateman's Drops" (see footnote 7).
+
+ [46] James Carter, Apothecary account book, Williamsburg
+ [1752-1773]. Manuscript original preserved at Colonial
+ Williamsburg, Virginia.
+
+American imprints seeking to promote the English patent medicines were
+certainly rare. The most significant example may be found in the
+Library of the New York Academy of Medicine.[47] In 1731 James Wallace,
+a New York merchant, became American agent for the sale of Dr.
+Bateman's Pectoral Drops. To help him with his new venture, Wallace
+took a copy of the London promotional pamphlet to a New York printer to
+be reproduced. The printer was John Peter Zenger, not yet an editor and
+three years away from the events which were to link his name
+inextricably with the concept of the freedom of the press. This 1731
+pamphlet may well have been the earliest work on any medical theme to
+be printed in New York.[48]
+
+ [47] _A short treatise of the virtues of Dr. Bateman's Pectoral
+ Drops_ (see footnote 6).
+
+ [48] Gertrude L. Annan, "Printing and medicine," _Bulletin of the
+ Medical Library Association_, March 1940, vol. 28, p. 155.
+
+Now and then a physician might frown on his fellows for reading such
+literature and prescribing such remedies, but he was in a minority.
+Colonial doctors, by and large, had no qualms about employing the
+packaged medicines. It was a doctor who first advertised Anderson's
+Pills and Bateman's Drops in Williamsburg;[49] it was another,
+migrating from England to the Virginia frontier, who founded a town and
+dosed those who came to dwell therein with Bateman's Drops,
+Turlington's Balsam, and other patent medicines.[50]
+
+ [49] Wyndham B. Blanton, _Medicine in Virginia in the eighteenth
+ century_, Richmond, Virginia, 1931, pp. 33-34.
+
+ [50] Maurice Bear Gordon, _Aesculapius comes to the colonies_,
+ Ventnor, New Jersey, 1949, p. 39.
+
+
+Complex Formulas and Distinctive Packages
+
+Indeed, the status of medical knowledge, medical need, and medical
+ethics in the 18th century permitted patent medicines to fit quite
+comfortably into the environment. As to what actually caused diseases,
+man knew little more than had the ancient Greeks. There were many
+theories, however, and the speculations of the learned often sound as
+quaint in retrospect as do the cocky assertions of the quack bills.
+Pamphlet warfare among physicians about their conflicting theories
+achieved an acrimony not surpassed by the competing advertisers of
+Stoughton's Elixir. The aristocratic practitioners of England, the
+London College of Physicians, refused to expand their ranks even at a
+time when there were in the city more than 1,300 serious cases of
+illness a day to every member of the College. The masses had to
+look elsewhere, and turned to apothecaries, surgeons, quacks, and
+self-treatment.[51] The lines were drawn even less sharply in colonial
+America, and there was no group to resemble the London College in
+prestige and authority. Medical laissez-faire prevailed. "Practitioners
+are laureated gratis with a title feather of Doctor," wrote a New
+Englander in 1690. "Potecaries, surgeons & midwifes are dignified
+acc[ording] to successe."[52] Such an atmosphere gave free rein to
+self-dosage, either with an herbal mixture found in the pages of a
+home-remedy book or with Daffy's Elixir.
+
+ [51] Fielding H. Garrison, _An introduction to the history of
+ medicine_, Philadelphia, 1924, pp. 405-408; and Richard H.
+ Shryock. _The development of modern medicine_, New York, 1947,
+ pp. 51-54.
+
+ [52] Kittredge, _op. cit._ (footnote 25).
+
+In the 18th century, drugs were still prescribed that dated back to the
+dawn of medicine. There were Theriac or Mithridatum, Hiera Picra (or
+Holy Bitters), and Terra Sigillata. Newer botanicals from the Orient
+and the New World, as well as the "chymicals" reputedly introduced by
+Paracelsus, found their way into these ancient formulas. Since the
+precise action of individual drugs in relation to given ailments was
+but hazily known, there was a tendency to blanket assorted
+possibilities by mixing numerous ingredients into the same formula. The
+formularies of the Middle Ages encouraged this so-called
+"polypharmacy." For example the _Antidotarium Nicolai_, written about
+A.D. 1100 at Salerno, described 38 ingredients in Confectio Adrianum,
+35 ingredients in Confectio Atanasia, and 48 ingredients in Confectio
+Esdra. Theriac or Mithridatum grew in complexity until by the 16th
+century it had some 60 different ingredients.
+
+It was in this tradition of complex mixtures that most of the patent
+medicines may be placed. Richard Stoughton claimed 22 ingredients for
+his Elixir, and Robert Turlington, in his patent specification, named
+27. Although other proprietors had shorter lists or were silent on the
+number of ingredients, a major part of their secrecy really lay in
+having complicated formulas. Even though rivals might detect the major
+active ingredients, the original proprietor could claim that only he
+knew all the elements in their proper proportions and the secret of
+their blending.
+
+Not only in complexity did the patent medicines resemble regular
+pharmaceutical compounds of the 18th century. In the nature of their
+composition they were blood brothers of preparations in the various
+pharmacopoeias and formularies. Indeed, there was much borrowing in
+both directions. An official formula of one year might blossom out the
+next in a fancy bottle bearing a proprietor's name. At the same time,
+the essential recipe of a patent medicine, deprived of its original
+cognomen and given a Latin name indicative of its composition or
+therapeutic nature, might suddenly appear in one of the official
+volumes.
+
+For example, the formula for Daffy's Elixir was adopted by the
+_Pharmacopoeia Londinensis_ in 1721 under the title of "Elixir Salutis"
+and later by the _Pharmacopoeia Edinburghensis_ as "Tinctura sennae
+composita" (Compound Senna Tincture). Similarly the essential formula
+for Stoughton's Elixir was adopted by the _Pharmacopoeia
+Edinburghensis_ as early as 1762 under the name of "Elixir Stomachium,"
+and later as "Compound Tincture of Gentian" (as in the _Pharmacopoeia
+of the Massachusetts Medical Society_ of 1808). Only two years after
+Turlington obtained his "Balsam of Life" patent, the _Pharmacopoeia
+Londinensis_ introduced a recipe under the title of "Balsamum
+Traumaticum" which eventually became Compound Tincture of Benzoin, with
+the synonym Turlington's Balsam. On the other hand, none of these early
+English patent medicines, including Stoughton's Elixir and Turlington's
+Balsam, offered anything new, except possibly new combinations or new
+proportions of ingredients already widely employed in medicine.
+Formulas similar in composition to those patented or marketed as "new
+inventions" can in every case be found in such 17th-century
+pharmacopoeias as William Salmon's _Pharmacopoeia Londinensis_.
+
+[Illustration: Figure 6.--BOTTLES OF BATEMAN'S PECTORAL DROPS, 19th
+century (left) and early 20th century (right), from the Samuel Aker,
+David and George Kass collection, Albany, New York. (_Smithsonian photo
+44287-A._)]
+
+Whatever similarities existed between the canons of regular pharmacy
+and the composition of patent medicines, there was a decided difference
+in the methods of marketing. Although patent medicines were often
+prescription items, they did not have to be. The way they looked on a
+shelf made them so easily recognizable that even the most loutish
+illiterate could tell one from another. As the nostrum proprietor did
+so much to pioneer in advertising psychology, so he also blazed a trail
+with respect to distinctive packaging. The popularity of the old
+English remedies, year in and year out, owed much to the fact that
+though the ingredients inside might vary (unbeknownst to the customer),
+the shape of the bottle did not. This was the reason proprietors raised
+such a hue and cry about counterfeiters. The secret of a formula might,
+if only to a degree, be retained, but simulation of bottle design and
+printed wrapper was easily accomplished, and to the average customer
+these externals were the medicine.
+
+This fundamental fact was to be recognized by the committee of
+Philadelphia pharmacists in 1824. "We are aware" the committeemen
+reported, "that long custom has so strongly associated the idea of the
+genuineness of the Patent medicines, with particular shapes of the
+vials that contain them, and with certain printed labels, as to render
+an alteration in them an affair of difficulty. Many who use these
+preparations would not purchase British Oil that was put up in a
+conical vial, nor Turlington's Balsam in a cylindrical one. The stamp
+of the excise, the king's royal patent, the seal and coat of arms which
+are to prevent counterfeits, the solemn caution against quacks and
+imposters, and the certified lists of incredible cures, [all these were
+printed on the bottle wrappers] have not even now lost their
+influence." Nor were they for years to come.
+
+Thus after 1754 the Turlington Balsam bottle was pear-shaped, with
+sloping shoulders, and molded into the glass in crude raised capitals
+were the proprietor's name and his claim of THE KINGS ROYAL PATENT.[53]
+Turlington during his life had made one modification. He explained it
+in a broadside, saying that "to prevent the Villainy of some Persons
+who buying up my empty Bottles, have basely and wickedly put therein a
+vile spurious Counterfeit-Sort," he had changed the bottle shape. The
+date molded into the glass on his supply of new genuine bottles was
+January 26, 1754.[54] This was, perhaps, a very fine point of
+difference from the perspective of the average customer, and in any
+case the bottle was hidden under its paper wrapper.
+
+ [53] "From past times an original bottle of Turlington's Balsam,"
+ _Chemist and Druggist_, September 23, 1905, vol. 67, p. 525;
+ Stewart Schackne, "Bottles," _American Druggist_, October 1933,
+ vol. 88, pp. 78-81, 186-188, 190, 194; Frederick Fairchild
+ Sherman, "Some early bottles," _Antiques_, vol. 3, pp. 122-123;
+ and Stephen Van Rensselaer, _Early American bottles and flasks_,
+ Peterborough, New Hampshire, 1926.
+
+ [54] Waldo R. Wedel and George B. Griffenhagen, "An English
+ balsam among the Dakota aborigines," _American Journal of
+ Pharmacy_, December 1954, vol. 126, pp. 409-415.
+
+The British Oil bottle was tall and slender and it rested on a square
+base. Godfrey's Cordial came in a conical vial with steep-pitched
+sides, the cone's point replaced by a narrow mouth.[55] Bateman's
+Pectoral Drops were packaged in a more common "phial"--a tall and
+slender cylindrical bottle.[56] Dalby's Carminative came in a bottle
+not unlike the Godfrey's Cordial bottle, except that Dalby's was
+impressed with the inscription DALBY'S CARMINATIV.[57] Steer's
+Opodeldoc bottles were cylindrical in shape, with a wide mouth; some
+apparently were inscribed OPODELDOC while others carried no such
+inscription. At least one brand of Daffy's Elixir was packaged in a
+globular bottle, according to a picture in a 1743 advertisement.[58]
+Speculation regarding the size and shape of the Stoughton bottle
+varies.[59] At least one Stoughton bottle was described as "Round
+amber. Tapered from domed shoulder to base. Long 5 in. bulged neck.
+Square flanged mouth. Flat base."[60]
+
+ [55] Sherman, _op. cit._ (footnote 53).
+
+ [56] Schackne, _op. cit._ (footnote 53).
+
+ [57] George S. and Helen McKearin, _American glass_, New York,
+ 1941.
+
+ [58] _Daily Advertiser_, London, October 29, 1743.
+
+ [59] George Griffenhagen, "Stodgy as a Stoughton bottle,"
+ _Journal of the American Pharmaceutical Association, Practical
+ Pharmacy Edition_, January 1956, vol. 17, p. 20; Mitford B.
+ Mathews, ed., _A dictionary of Americanisms on historical
+ principles_, Chicago, 1951, 2 vols.; Bertha Kitchell Whyte,
+ _Wisconsin heritage_, Boston, 1954; Charles Earle Funk, _Heavens
+ to Betsy! and other curious sayings_, New York, 1955.
+
+ [60] James H. Thompson, _Bitters bottles_, Watkins Glen, New
+ York, 1947, p. 60.
+
+Hooper's and Anderson's Scots Pills were, of course, not packaged in
+bottles (at least not the earliest), but were instead sold in the
+typical oval chip-wood pill boxes. On the lid of the box containing
+Hooper's Pills was stamped this inscription: DR. JOHN HOOPER'S FEMALE
+PILLS: BY THE KING'S PATENT 21 JULY 1743 NO. 592. So far no example or
+illustration of Anderson's Scots Pills has been found. At least one
+producer, it will be remembered (page 157), sealed the box in black wax
+bearing a lion rampant, three mallets argent, and the bust of Dr.
+Anderson.
+
+
+Source of Supply Severed
+
+On September 29, 1774, John Boyd's "medicinal store" in Baltimore
+followed the time-honored custom of advertising in the _Maryland
+Gazette_ a fresh supply of medicines newly at hand from England. To
+this intelligence was added a warning. Since nonimportation agreements
+by colonial merchants were imminent, which bade fair to make goods hard
+to get, customers would be wise to make their purchases before the
+supply became exhausted. Boyd's prediction was sound. The Boston Tea
+Party of the previous December had evoked from Parliament a handful of
+repressive measures, the Intolerable Acts, and at the time of Boyd's
+advertisement, the first Continental Congress in session was soon to
+declare that all imports from Great Britain should be halted.
+
+[Illustration: Figure 7.--BOTTLES OF BRITISH OIL, 19th and early 20th
+century, from the Samuel Aker, David and George Kass collection,
+Albany, New York. (_Smithsonian photo 44201-B._)]
+
+This Baltimore scare advertising may well have been heeded by Boyd's
+customers, for trade with the mother country had been interrupted
+before; in the wake of the Townshend Acts in 1767, when Parliament had
+placed import duties on various products, including tea, American
+merchants in various cities had entered into nonimportation agreements.
+Certainly, there was a decided decrease in the Boston advertising of
+patent medicines received from London. With respect to imports of any
+kind, it became necessary to explain, and one merchant noted that his
+goods were "the Remains of a Consignment receiv'd before the
+Non-Importation Agreement took place."[61] When Parliament yielded to
+the financial pressure and abolished all the taxes but the one on tea,
+nonimportation collapsed. This fact is reflected in an advertisement
+listing nearly a score of patent medicines, including the remedies of
+Turlington, Bateman, the Bettons, Anderson, Hooper, Godfrey, Daffy, and
+Stoughton, as "Just come to Hand and Warranted Genuine" on Captain
+Dane's ship, "directly from the Original Warehouse kept by DICEY and
+OKELL in Bow Street, London."[62]
+
+ [61] _Massachusetts Gazette_, Boston, December 21, 1769.
+
+ [62] _Ibid._, April 25, 1771.
+
+The days of such ample importations, however, were doomed, as commerce
+fell prey to the growing revolutionary agitation. The last medical
+advertisement in the _Massachusetts Gazette and Boston Weekly
+News-Letter_, before its demise the following February, appeared five
+months after the Battles of Lexington and Concord.[63] The apothecary
+at the Sign of the Unicorn was frank about the situation. He had
+imported fresh drugs and medicines every fall and spring up to the
+preceding June. He still had some on hand. Doctors and others should be
+advised.
+
+ [63] _Ibid._, September 7, 1775.
+
+Implicit in the advertisement is the suggestion that the securing of
+new supplies under the circumstances would be highly uncertain. That
+pre-war stocks did hold out, sometimes well into the war years may be
+deduced from a Williamsburg apothecary's advertisement.[64] W. Carter
+took the occasion of the ending of a partnership with his brother to
+publish a sort of inventory. Along with the "syrup and ointment pots,
+all neatly painted and lettered," the crabs eyes and claws, the Spanish
+flies, he listed a dozen patent medicines, including the remedies of
+Anderson, Bateman, and Daffy.
+
+ [64] _Virginia Gazette_ (edited by Dixon and Nicholson),
+ Williamsburg, June 12, 1779.
+
+Even the British blockade failed to prevent patent medicines from being
+shipped from wholesaler to retailer. In the account book of a Salem,
+Massachusetts, apothecary,[65] the following entry appears:
+
+ 4 cases Containing
+ 1 Dozn Bottles Godfreys Cordial 4/
+ 5 Dozn Do Smaller Turling Bals 18/
+ 8 Dozn Bettons British Oil 8/
+ 6-1/2 Dozn Hoopers Female Pills 10/
+ 4 Dozn nd 8 Boxs And. Pills 10/
+
+ SALEM APRIL 8th 1777
+
+ The above 13 packages and 4 cases of medicines are ship'd on Board
+ the Sloop Called the Two Brothers Saml West Master. On Account and
+ [illegible word] of Mr. Oliver Smith of Boston Apothecary and to
+ him consigned. The cases are unmarked being ship'd at Night. Error
+ Excepted Jon. Waldo.
+
+ [65] Jonathon Waldo, Apothecary account book, Salem,
+ Massachusetts [1770-1790]. Manuscript original preserved in
+ the Library of the Essex Institute, Salem, Mass.
+
+[Illustration: Figure 8.--DALBY'S CARMINATIVE, two sides of a bottle
+from the McKearin collection, Hoosick Falls, New York. (_Smithsonian
+photo 44287-C._)]
+
+The sloop was undoubtedly one of the small coastal type ships employed
+by the colonists, and the British blockade required such ominous
+precautions as "unmarked cases" and "ship'd by Night."
+
+Such random assortments of prewar importations could hardly have met
+the American demand for the old English patent medicines created by a
+half century of use. Doubtless many embattled farmers had to confront
+their ailments without the accustomed English-made remedies. However,
+as early as the 1750's, at least two of the English patent medicines,
+Daffy's and Stoughton's Elixirs, were being compounded in the
+colonies and packaged in empty bottles shipped from England.
+Apothecary Carter of Williamsburg ordered sizable quantities of empty
+"Stoughton Vials" from 1752 through 1770, and occasionally ordered
+empty Daffy's bottles.[66] In 1774 apothecary Waldo of Salem noted
+the receipt from England of "1 Groce Stoughton Phials" and "1 Groce
+Daffy's Do."[67] Joseph Stansbury, who sold china and glass in
+Philadelphia, advertised "Daffy's Elixir Bottles" a week after the
+Declaration of Independence.[68] Stoughton's and Daffy's Elixirs,
+therefore, were being compounded by the American apothecaries during
+the Revolutionary War. Formulas for both preparations were official
+in the London and Edinburgh pharmacopoeias, as well as in unofficial
+formularies like Quincy's _Pharmacopoeias officinalis extemporanea_
+of 1765. All these publications were used widely by American
+physicians and apothecaries.
+
+ [66] Carter, _op. cit._ (footnote 46).
+
+ [67] Waldo, _op. cit._ (footnote 65).
+
+ [68] _Pennsylvania Gazette_, Philadelphia, July 11, 1776.
+
+It is not known how extensively, during the struggle for independence,
+this custom was adopted for English patent medicines other than Daffy's
+and Stoughton's. However, imitation of English patent medicines in
+America was to increase, and it contributed to the chaos that beset the
+nostrum field when the war was over and the original articles from
+England were once more available. And they were bought. An
+advertisement at a time when the fighting was over and peace
+negotiations were still under way indicated that the Baltimore post
+office had half a dozen of the familiar English remedies for sale.[69]
+Two years later a New York store turned to tortured rhyme to convey the
+same message:[70]
+
+ Medicines approv'd by royal charter,
+ James, Godfry, Anderson, Court-plaster,
+ With Keyser's, Hooper's Lockyer's Pills,
+ And Honey Balsam Doctor Hill's;
+ Bateman and Daffy, Jesuits drops,
+ And all the Tinctures of the shops,
+ As Stoughton, Turlington and Grenough,
+ Pure British Oil and Haerlem Ditto....
+
+ [69] _Maryland Journal and Baltimore Gazette_, Baltimore, October
+ 29, 1782.
+
+ [70] _New York Packet and the American Advertiser_, New York,
+ October 11, 1784.
+
+Later in the decade, the Salem apothecary, Jonathon Waldo, made a list
+of "An assortment [of patent medicines] Usually Called For." The
+imported brand of Turlington's Balsam, Waldo stated, was "very dear" at
+36 shillings a dozen, adding that his "own" was worth but 15 shillings
+for the same quantity. The English original of another nostrum, Essence
+of Peppermint, he listed at 18 shillings a dozen, his own at a mere
+10/6.[71] Despite the price differential, importations continued. A
+Beverly, Massachusetts, druggist, Robert Rantoul, in 1799 ordered from
+London filled boxes and bottles of Anderson's Pills, Bateman's Drops,
+Steer's Opodeldoc, and Turlington's Balsam, along with the empty vials
+in which to put British Oil and Essence of Peppermint.[72] For decades
+thereafter the catalogs of wholesale drug firms continued to specify
+two grades of various patent medicines for sale, termed "English" and
+"American," "true" and "common," or "genuine" and "imitation."[73] This
+had not been the case in patent medicine listings of 18th-century
+catalogs.[74]
+
+ [71] Waldo, _op. cit._ (footnote 65).
+
+ [72] Robert Rantoul, Apothecary daybooks, 3 vols., Beverly,
+ Massachusetts [1796-1812]. Manuscript originals preserved in the
+ Beverly Historical Society. Also see Robert W. Lovett, "Squire
+ Rantoul and his drug store," _Bulletin of the Business Historical
+ Society_, June 1951, vol. 25, pp. 99-114.
+
+ [73] Joel and Jotham Post, _A catalogue of drugs, medicines &
+ chemicals, sold wholesale & retail, by Joel and Jotham Post,
+ druggists, corner of Wall and William-Streets_, New York, 1804;
+ Massachusetts College of Pharmacy, _Catalogue of the materia
+ medica and of the pharmaceutical preparations, with the uniform
+ prices of the Massachusetts College of Pharmacy_, Boston, 1828;
+ George W. Carpenter, _Essays on some of the most important
+ articles of the materia medica ... to which is added a catalogue
+ of medicines, surgical instruments, etc._, Philadelphia, 1834.
+
+ [74] John Dunlap, _Catalogus medicinarum et pharmacorum_,
+ Philadelphia, 1771; John Day, _Catalogue of drugs, chymical and
+ galenical preparations, shop furniture, patent medicines, and
+ surgical instruments sold by John Day and Company, druggists and
+ chymists in second-street_, Philadelphia, 1771; George
+ Griffenhagen, "The Day-Dunlap 1771 pharmaceutical catalog,"
+ _American Journal of Pharmacy_, September 1955, vol. 127, pp.
+ 296-302; also _The New York Physician and American Medicine_, May
+ 1956, vol. 46, pp. 42-44; Smith and Bartlett, _Catalogue of drugs
+ and medicines, instruments and utensils, dyestuffs, groceries,
+ and painters' colours, imported, prepared, and sold, by Smith and
+ Bartlett, at their druggists store and apothecaries shop_,
+ Boston, 1795.
+
+[Illustration: Figure 9.--GODFREY'S CORDIAL, 19th-century bottles from
+the Samuel Aker, David and George Kass collection, Albany, New York.
+(_Smithsonian photo 44201-C._)]
+
+In buying Anderson's and Bateman's remedies from London in 1799, Robert
+Rantoul of Massachusetts specified that they be secured from Dicey. It
+will be remembered that 60 years earlier William Dicey, John Cluer, and
+Robert Raikes were the group of entrepreneurs who had aided Benjamin
+Okell in patenting the pectoral drops bearing Bateman's name. Then and
+throughout the century, this concern continued to operate a warehouse
+in the Bow Churchyard, Cheapside, London. In 1721, it was known as the
+"Printing-house and Picture Warehouse" of John Cluer, printer,[75] but
+by 1790, it was simply the "Medicinal Warehouse" of Bow Churchyard,
+Cheapside. This address lay in the center of the London area whence
+came nearly all of the British goods exported to America.[76] It had
+been the location of many merchants who had migrated to New England in
+the 17th century, and these newcomers had done business with their
+erstwhile associates who did not leave home. Thus were started trade
+channels which continued to run. The Bow Churchyard Warehouse may have
+been the major exporter of English patent medicines to colonial
+America, although others of importance were located in the same London
+region, in particular Robert Turlington of Lombard Street and Francis
+Newbery of St. Paul's Churchyard. The significance of the fact that
+there were key suppliers of patent medicines for the American market
+lies in the selection process which resulted. Out of the several
+hundred patent medicines which 18th-century Britain had available,
+Americans dosed themselves with that score or more which the major
+exporters shipped to colonial ports.
+
+ [75] _London Mercury_, London, August 19-26, 1721.
+
+ [76] Bernard Bailyn, _The New England merchants in the
+ seventeenth century_, Cambridge, Massachusetts, 1955, pp. 35-36.
+
+Not only did the Bow Churchyard Warehouse firm have Bateman's Drops. It
+will be remembered that in 1721 they advertised that they were
+preparing Daffy's Elixir. In 1743, they and Newbery were made exclusive
+vendors of Hooper's Pills.[77] By 1750, the firm was also marketing
+British Oil, Anderson's Pills, and Stoughton's Elixir.[78] Turlington
+in 1755 was selling not only his Balsam of Life, but was also vending
+Daffy's Elixir, Godfrey's Cordial, and Stoughton's Elixir.[79] After
+the tension of the Townshend Acts, it was the Bow Churchyard Warehouse
+which supplied a Boston apothecary with a large supply of nostrums,
+including all the eight patent medicines then in existence of the ten
+with which this discussion is primarily concerned.[80] On November 29,
+1770, the _Virginia Gazette_ (edited by Purdie and Dixon) reported a
+shipment, including Bateman's, Hooper's, Betton's, Anderson's, and
+Godfrey's remedies, just received "from Dr. Bateman's original
+wholesale warehouse in London" (the Bow Churchyard Warehouse). When
+Dalby's Carminative and Steer's Opodeldoc came on the market in the
+1780's, it was Francis Newbery who had them for sale. Both the Newbery
+and Dicey (Bow Churchyard Warehouse) firms continued to operate in the
+post-Revolutionary years. Thus, it was no accident but rather vigorous
+commercial promotion over the decades, that resulted in the most
+popular items on the Dicey and Newbery lists appearing in the
+Philadelphia College of Pharmacy pamphlet published in 1824. And
+although the same old firms continued to export the same old medicines
+to the new United States, the back of the business was broken. The
+imitation spurred by wartime necessity became the post-war pattern.
+
+ [77] _Daily Advertiser_, London, September 23, 1743.
+
+ [78] "Dr. Bateman's Drops" (see footnote 7).
+
+ [79] Turlington, _op. cit._ (footnote 15).
+
+ [80] _Massachusetts Gazette_, Boston, December 21, 1769.
+
+The key recipes were to be found in formula books. Beginning in the
+1790's, even American editions of John Wesley's _Primitive physic_
+included formulas for Daffy's, Turlington's, and Stoughton's remedies
+which the founder of Methodism had introduced into English editions of
+this guidebook to health shortly before his death.[81]
+
+ [81] John Wesley, _Primitive physic_, 21st ed., London, 1785;
+ _ibid._, 22nd ed., London, 1788; _ibid._, 16th Amer. ed.,
+ Trenton, 1788; _ibid._, 22nd Amer. ed., Philadelphia, 1791;
+ George Dock, "The 'primitive physic' of Rev. John Wesley,"
+ _Journal of the American Medical Association_, February 20, 1915,
+ vol. 64, pp. 629-638.
+
+The homemade versions, as Jonathon Waldo had recorded (see p. 171),
+were about half as costly. The state of affairs at the turn of the new
+century is illustrated in the surviving business papers of the Beverly
+druggist, Robert Rantoul. In 1799 he had imported the British Oil and
+Essence of Peppermint bottles. In 1802 he reordered the latter,
+specifying that they should not have molded in the glass the words "by
+the Kings Patent." Rantoul wrote a formula for this nostrum in his
+formula book, and from it he filled 66 bottles in December 1801 and 202
+bottles in June 1803. About the same time he began making and bottling
+Turlington's Balsam, ordering bottles of two sizes from London. His
+formula book contains these entries: "Jany 4th, 1804 filled 54 small
+turlingtons with 37 oz. Balsam," and "Jany 20th, 1804 filled 144 small
+turlingtons with 90-1/4 oz. Balsam and 9 Large Bottles with 8-1/4
+oz."[82]
+
+ [82] Rantoul, _op. cit._ (footnote 72).
+
+Two decades later the imitation of the English proprietaries was even
+bigger business. In 1821 William A. Brewer became apprenticed to a
+druggist in Boston. A number of the old English brands, he recalled,
+were still imported and sold at the time. But his apprenticeship years
+were heavily encumbered with duties involving the American versions.
+"Many, very many, days were spent," Brewer remembered, "in compounding
+these imitations, cleaning the vials, fitting, corking, labelling,
+stamping with fac-similes of the English Government stamp, and in
+wrapping them, with ... little regard to the originator's rights, or
+that of their heirs...." The British nostrums chiefly imitated in this
+Boston shop were Steer's, Bateman's, Godfrey's, Dalby's, Betton's, and
+Stoughton's. The last was a major seller. The store loft was mostly
+filled with orange peel and gentian, and the laboratory had "a heavy
+oaken press, fastened to the wall with iron clamps and bolts, which was
+used in pressing out 'Stoughton's Bitters,' of which we usually
+prepared a hogshead full at one time." A large quantity was needed. In
+those days, Brewer asserted, "almost everybody indulged in Stoughton's
+elixir as morning bitters." [83]
+
+ [83] William A. Brewer, "Reminiscences of an old pharmacist."
+ _Pharmaceutical Record_, August 1, 1884, vol. 4, p. 326.
+
+[Illustration: Figure 10.--GODFREY'S CORDIAL, early 20th century
+bottles manufactured in the U.S.A. (_U.S. National Museum cat. Nos.
+M-6989, and M-6990; Smithsonian photo 44287 B._)]
+
+Other drugstores certainly followed the practice of Brewer's employer,
+in cleaning up and refilling bottles that had previously been drained
+of their old English medicines. The chief source of bottles to hold the
+American imitations, however, was the same as that to which Waldo and
+Rantoul had turned, English glass factories. It was not so easy for
+Americans to fabricate the vials as it was for them to compound the
+mixtures to fill them. In the years before the War of 1812, the British
+glass industry maintained a virtual monopoly of the specially-shaped
+bottles for Bateman's, Turlington's, and the other British remedies.
+When in the 1820's the first titan of made-in-America nostrums, Thomas
+W. Dyott of Philadelphia, appeared upon the scene, this venturesome
+entrepreneur decided to make bottles not only for his own assorted
+remedies but also for the popular English brands. In time he succeeded
+in improving the quality of American bottle glass and in drastically
+reducing prices. The standard cost for most of the old English vials
+under the British monopoly had been $5.50 a gross. By the early 1830's
+Dyott had cut the price to under two dollars.[84]
+
+ [84] _Democratic Press_, Philadelphia, July 1 and October 28,
+ 1824; Thomas W. Dyott, _An exposition of the system of moral and
+ mental abor, established at the glass factory of Dyottsville_,
+ Philadelphia, 1833; and Joseph D. Weeks, "Reports on the
+ manufacture of glass," _Report of the manufactures of the United
+ States at the tenth census_, Washington, D. C, 1883.
+
+[Illustration: Figure 11.--AN ORIGINAL PACKAGE OF HOOPER'S PILLS, from
+the Samuel Aker, David and George Kass collection, Albany, New York.
+(_Smithsonian photo_ 44201.)]
+
+Other American glass manufactories followed suit. For example, in 1835
+the Free Will Glass Manufactory was making "Godfrey's Cordial,"
+"Turlington's Balsam," and "Opodeldoc Bitters bottles."[85] An 1848
+broadside entitled "The Glassblowers' List of Prices of Druggist's
+Ware," a broadside preserved at the Smithsonian Institution, includes
+listings for Turlington's Balsam, Godfrey's Cordial, Dalby's and Small
+and Large Opodeldoc bottles, among many other American patent medicine
+bottles.
+
+ [85] Van Rensscalar, _op. cit._, (footnote 53), p. 151.
+
+In the daybook of the Beverly, Massachusetts, apothecary,[86] were
+inscribed for Turlington's Balsam, three separate formulas, each
+markedly different from the others. A Philadelphia medical journal in
+1811 contained a complaint that Americans were using calomel in the
+preparation of Anderson's Scots Pills, and that this practice was a
+deviation both from the original formula and from the different but
+still all-vegetable formula by which the pills were being made in
+England.[87] Various books were published revealing the "true"
+formulas, in conflicting versions.[88]
+
+ [86] Rantoul, _op. cit._ (footnote 72).
+
+ [87] _Philadelphia Medical Museum_, new ser., vol. 1, p. 130,
+ 1811.
+
+ [88] _Formulae selectae; or a collection of prescriptions of
+ eminent physicians, and the most celebrated patent medicines_,
+ New York, 1818; John Ayrton Paris, _Pharmacologia; or the history
+ of medicinal substances, with a view to establish the art of
+ prescribing and of composing extemporaneous formulae upon fixed
+ and scientific principles_, New York, 1822.
+
+
+Philadelphia College of Pharmacy Formulary
+
+As the years went by and therapeutic laissez-faire continued to
+operate, conditions worsened. By the early 1820's, the old English
+patent medicines, whether of dwindling British vintage or of burgeoning
+American manufacture, were as familiar as laudanum or castor oil.
+
+With the demand so extensive and the state of production so chaotic,
+the officials of the new Philadelphia College of Pharmacy were
+persuaded that remedial action was mandatory. In May 1822, the Board of
+Trustees resolved to appoint a 5-man committee "to select from such
+prescriptions for the preparation of Patent Medicines ..., as may be
+submitted to them by the members of the College, those which in their
+opinion, may be deemed most appropriate for the different
+compositions."
+
+The committee chose for study "eight of the Patent Medicines most in
+use," and sought to ascertain what ingredients these ancient remedies
+ought by right to contain. Turning to the original formulas, where
+these were given in English patent specifications, the pharmacists soon
+became convinced that the information provided by the original
+proprietors served "only to mislead."
+
+If the patent specifications were perhaps intentionally confusing, the
+committee inquired, how could the original formulas really be known?
+This quest seemed so fruitless that it was not pursued. Instead the
+pharmacists turned to American experience in making the English
+medicines. From many members of the College, and from other pharmacists
+as well, recipes were secured. The result was shocking. Although almost
+every one came bolstered with the assertion that it was true and
+genuine, the formulas differed so markedly one from the other, the
+committee reported, as to make "the task of reformation a very
+difficult one." Indeed, in some cases, when two recipes bearing the
+same old English name were compared, they were found to contain not one
+ingredient in common. In other cases, the proportions of some basic
+ingredient would vary widely. All the formulas collected for Bateman's
+Pectoral Drops, for instance, contained opium, but the amount of opium
+to liquid ingredients in one formula submitted was 1 to 14, while in
+another it was 1 to 1,000.
+
+Setting forth boldly to strip these English nostrums of "their
+extravagant pretensions," the committee sought to devise formulas for
+their composition as simple and inexpensive as possible while yet
+retaining the "chief compatible virtues" ascribed to them on the
+traditional wrappers.
+
+Hooper's Female Pills had been from the beginning a cathartic and
+emmenagogue. However, only aloes was common to all the recipes
+submitted to the committee. This botanical, which still finds a place
+in laxative products today, was retained by the committee as the
+cathartic base, and to it were added "the Extract of Hellebore, the
+Sulphate of Iron and the Myrrh as the best emmenagogues."
+
+Anderson's Scots Pills had been a "mild" purgative throughout its long
+career, varying in composition "according to the judgement or fancy of
+the preparer." Paris, an English physician, had earlier reported that
+these pills consisted of aloes and jalap; the committee decided on
+aloes, with small amounts of colocynth and gamboge, as the purgatives
+of choice.
+
+Of Bateman's Pectoral Drops more divergent versions existed than of any
+of the others. The committee settled on a formula of opium and camphor,
+not unlike paragoric in composition, with catachu, anise flavoring, and
+coloring added. Godfrey's Cordial also featured opium in widely varying
+amounts. The committee chose a formula which would provide a grain of
+opium per ounce, to which was added sassafras "as the carminative which
+has become one of the chief features of the medicine."
+
+English apothecary Dalby had introduced his "Carminative" for "all
+those fatal Disorders in the Bowels of Infants." The committee decided
+that a grain of opium to the ounce, together with magnesia and three
+volatile oils, were essential "for this mild carminative and laxative
+... for children."
+
+Instead of the complex formula described by Robert Turlington for his
+Balsam of Life, the committee settled on the official formula of
+Compound Tincture of Benzoin, with balsam of peru, myrrh, and angelica
+root added, to produce "an elegant and rich balsamic tincture." On the
+other hand, the committee adopted "with slight variations, the
+Linimentum Saponis of the old London Dispensatory" to which they, like
+Steers, added only ammonia.
+
+The committee found two distinct types of British Oil on the market.
+One employed oil of turpentine as its basic ingredient, while the other
+utilized flaxseed oil. The committee decided that both oils, along with
+several others in lesser quantities, were necessary to produce a
+medicine "as exhibited in the directions" sold with British Oil. "Oil
+of Bricks" which apparently was the essential ingredient of the Betton
+British Oil, was described by the committee as "a nauseous and
+unskilful preparation, which has long since been banished from the
+Pharmacopoeias."
+
+Thus the Philadelphia pharmacists devised eight new standardized
+formulas, aimed at retaining the therapeutic goals of the original
+patent medicines, while brought abreast of current pharmaceutical
+knowledge. Recognizing that the labeling had long contained
+"extravagant pretensions and false assertions," the committee
+recommended that the wrappers be modified to present only truthful
+claims. If the College trustees should adopt the changes suggested, the
+committee concluded optimistically, then "the reputation of the College
+preparations would soon become widely spread, and we ... should reap
+the benefit of the examination which has now been made, in an increased
+public confidence in the Institution and its members; the influence of
+which would be felt in extending the drug business of our city."[89]
+
+ [89] Philadelphia College of Pharmacy, _Formulae for the
+ preparation of eight patent medicines, adopted by the
+ Philadelphia College of Pharmacy_, May 4, 1824; Joseph W.
+ England, ed., _The first century of the Philadelphia College of
+ Pharmacy_, 1821-1921, Philadelphia, 1922.
+
+The trustees felt this counsel to be wise, and ordered 250 copies of
+the 12-page pamphlet to be printed. So popular did this first major
+undertaking of the Philadelphia College prove that in 1833 the formulas
+were reprinted in the pages of the journal published by the
+College.[90] Again the demand was high, few numbers of the publication
+were "more sought after," and in 1839 the formulas were printed once
+again, this time with slight revisions.[91]
+
+ [90] "Patent medicines," _Journal of the Philadelphia College of
+ Pharmacy_, April 1833, vol. 5, pp. 20-31.
+
+ [91] C. Ellis, "Patent medicines," _American Journal of
+ Pharmacy_, April 1839, new ser., vol. 5, pp. 67-74.
+
+Thus had the old English patent medicines reached a new point in their
+American odyssey. They had first crossed the Atlantic to serve the
+financial interests of the men who promoted them. During the Revolution
+they had lost their British identity while retaining their British
+names. The Philadelphia pharmacists, while adopting them and reforming
+their character, did not seek to monopolize them, as had the original
+proprietors. They now could work for every man.
+
+
+English Patent Medicines Go West
+
+The double reprinting of the formulas was one token of the continuing
+role in American therapy of the old English patent medicines. There
+were others. In 1829 with the establishment of a school of pharmacy in
+New York City, the Philadelphia formulas were accepted as standard. The
+new labels devised by the Philadelphians with their more modest claims
+of efficacy had a good sale.[92] It was doubtless the Philadelphia
+recipes which went into the Bateman and Turlington and Godfrey vials
+with which a new druggist should be equipped "at the outset of
+business," according to a book of practical counsel.[93] To local
+merchants who lacked the knowledge or time to do it themselves,
+drummers and peddlers vended the medicines already bottled. "Doctor"
+William Euen of Philadelphia issued a pamphlet in 1840 to introduce his
+son to "Physicians and Country Merchants." His primary concern was
+dispensing nostrums bearing his own label, but his son was also
+prepared to take orders for the old English patent medicines.[94]
+Manufacturers and wholesalers of much better repute were prepared to
+sell bottles for the same brands, empty or filled.
+
+ [92] England, _op. cit._ (footnote 89), pp. 73, 103.
+
+ [93] Carpenter, _op. cit._ (footnote 73).
+
+ [94] William Euen, _A short expose on quackery ... or,
+ introduction of his son to physicians and country merchants_,
+ Philadelphia, 1840.
+
+[Illustration: Figure 12.--ENGLISH AND AMERICAN BRANDS OF HOOPER'S
+FEMALE PILLS, an assortment of packages of from the Samuel Aker, David
+and George Kass collection, Albany, New York. (_Smithsonian photo
+44201-D._)]
+
+In the early 1850's a young pharmacist in upstate New York,[95] using
+"old alcohol barrels for tanks," worked hard at concocting Bateman's
+and Godfrey's and Steer's remedies. John Uri Lloyd of Cincinnati
+recalled having compounded Godfrey's Cordial and Bateman's Drops,
+usually making ten gallons in a single batch.[96] Out in Wisconsin,
+another druggist was buying Godfrey's Cordial bottles at a dollar for
+half a gross, sticking printed directions on them that cost twelve
+cents for the same quantity, and selling the medicine at four ounces
+for a quarter.[97] He also sold British Oil and Opodeldoc, the same old
+English names dispensed by a druggist in another Wisconsin town, who in
+addition kept Bateman's Oil in stock at thirteen cents the bottle.[98]
+Godfrey's was listed in the 1860 inventory of an Illinois general store
+at six cents a bottle.[99]
+
+ [95] James Winchell Forbes, "The memoirs of an American
+ pharmacist," _Midland Druggist and Pharmaceutical Review_, 1911,
+ vol. 45, pp. 388-395.
+
+ [96] John Uri Lloyd, "Eclectic fads," _Eclectic Medical Journal_,
+ October 1921, vol. 81, p. 2.
+
+ [97] Cody & Johnson Drug Co., Apothecary daybooks, Watertown,
+ Wisconsin [1851-1872]. Manuscript originals preserved in the
+ State Historical Society of Wisconsin, cataloged under "Cady."
+
+ [98] Swarthout and Silsbee, Druggists daybook, Columbus,
+ Wisconsin [1852-1853]. Manuscript original preserved in the State
+ Historical Society of Wisconsin.
+
+ [99] McClaughry and Tyler, Invoice book, Fountain Green, Illinois
+ [1860-1877]. Manuscript original preserved in the Illinois State
+ Historical Society, Springfield.
+
+Farther west the same familiar names appeared. Indeed, the old English
+patent medicines had long since moved westward with fur trader and
+settler. As early as 1783, a trader in western Canada, shot by a rival,
+called for Turlington's Balsam to stop the bleeding. Alas, in this
+case, the remedy failed to work.[100] In 1800 that inveterate Methodist
+traveler, Bishop Francis Asbury, resorted to Stoughton's Elixir when
+afflicted with an intestinal complaint.[101] In 1808, some two months
+after the first newspaper began publishing west of the Mississippi
+River, a local store advised readers in the vicinity of St. Louis that
+"a large supply of patent medicines" had just been received, among them
+Godfrey's Cordial, British Oil, Turlington's Balsam, and Steer's
+"Ofodeldo [sic]."[102]
+
+ [100] Harold A. Innis, _Peter Pond, fur trader and adventurer_,
+ Toronto, 1930.
+
+ [101] Peter Oliver, "Notes on science, medicine and public health
+ in the United States in the year 1800," _Bulletin of the History
+ of Medicine_. 1944, vol. 16, p. 129.
+
+ [102] Isaac Lionberger, "Advertisements in the Missouri Gazette,
+ 1808-1811," _Missouri Historical Society Collections_, 1928-1931,
+ vol. 6, p. 21.
+
+Turlington's product played a particular role in the Indian trade, thus
+demonstrating that the red man has not been limited in nostrum history
+to providing medical secrets for the white man to exploit. Proof of
+this has been demonstrated by archaeologists working under the auspices
+of the Smithsonian Institution in both North and South Dakota. Two
+pear-shaped bottles with Turlington's name and patent claims embossed
+in the glass were excavated by a Smithsonian Institution River Basin
+Surveys expedition in 1952, on the site of an old trading post known as
+Fort Atkinson or Fort Bethold II, situated some 16 miles southeast of
+the present Elbowoods, North Dakota. In 1954 the North Dakota
+Historical Society found a third bottle nearby. These posts, operated
+from the mid-1850's to the mid-1880's, served the Hidatsa and Mandan
+Indians who dwelt in a town named Like-a-Fishhook Village. The medicine
+bottles were made of cast glass, light green in color, probably of
+American manufacture. More interesting is the bottle from South Dakota.
+It was excavated in 1923 near Mobridge at a site which was the
+principal village of the Arikara Indians from about 1800 to 1833, a
+town visited by Lewis and Clark as they ascended the Missouri River in
+1804. This bottle, made of English lead glass and therefore an imported
+article, was unearthed from a grave in the Indian burying ground.
+Throughout history the claims made in behalf of patent medicines have
+been extreme. This Turlington bottle, however, affords one of the few
+cases on record wherein such a medicine has been felt to possess a
+postmortem utility.[103]
+
+ [103] Wedel and Griffenhagen, _op. cit._ (footnote 54).
+
+Fur traders were still using old English patent medicines at
+mid-century. Four dozen bottles of Turlington's Balsam were included in
+an "Inventory of Stock the property of Pierre Chouteau, Jr. and Co.
+U[pper], M[issouri]. On hand at Fort Benton 4th May 1851...."[104] In
+the very same year, out in the new State of California, one of the
+early San Francisco papers listed Stoughton's Bitters as among the
+merchandise for sale at a general store.[105]
+
+ [104] A. McDonnell, _Contributions to the Historical Society of
+ Montana_, 1941, vol. 10, pp. 202, 217.
+
+ [105] _California Daily Courier_, San Francisco, April 25, 1851.
+
+Newspaper advertising of the English proprietaries--even the mere
+listing so common during the late colonial years--became very rare
+after the Philadelphia College of Pharmacy pamphlet was issued.
+Apothecary George J. Fischer of Frederick, Maryland, might mention
+seven of the old familiar names in 1837,[106] and another druggist in
+the same city might present a shorter list in 1844,[107] but such
+advertising was largely gratuitous. Since the English patent medicines
+had become every druggist's property, people who felt the need of such
+dosage would expect every druggist to have them in stock. There was no
+more need to advertise them than there was to advertise laudanum or
+leeches or castor oil. Even the Supreme Court of Massachusetts in 1837
+took judicial cognizance of the fact that the old English patent
+medicine names had acquired a generic meaning descriptive of a general
+class of medicines, names which everyone was free to use and no one
+could monopolize.[108]
+
+ [106] _Political Examiner_, Frederick, Maryland, April 19, 1837.
+
+ [107] _Frederick Examiner_, Frederick, Maryland, January 31,
+ 1844.
+
+ [108] _Massachusetts Supreme Court_, Thomson vs. Winchester, 19
+ Pick (Mass.), p. 214, March 1837.
+
+As the years went by, and as advertising did not keep the names of the
+old English medicines before the eyes of customers, it is a safe
+assumption that their use declined. Losing their original proprietary
+status, they were playing a different role. New American proprietaries
+had stolen the appeal and usurped the function which Bateman's Drops
+and Turlington's Balsam had possessed in 18th-century London and Boston
+and Williamsburg. As part of the cultural nationalism that had
+accompanied the Revolution, American brands of nostrums had come upon
+the scene, promoted with all the vigor and cleverness once bestowed in
+English but not in colonial American advertising upon Dalby's
+Carminative and others of its kind. While these English names retreated
+from American advertising during the 19th century, vast blocks of space
+in the ever-larger newspapers were devoted to extolling the merits of
+Dyott's Patent Itch Ointment, Swaim's Panacea, and Brandreth's Pills.
+More and more Americans were learning how to read, as free public
+education spread. Persuaded by the frightening symptoms and the
+glorious promises, citizens with a bent toward self-dosage flocked to
+buy the American brands. Druggists and general stores stocked them and
+made fine profits.[109] While bottles of British Oil sold two for a
+quarter in 1885 Wisconsin, one bottle of Jayne's Expectorant retailed
+for a dollar.[110] It is no wonder that, although the old English names
+continue to appear in the mid-19th-century and later druggists'
+catalogs and price currents,[111] they are muscled aside by the
+multitude of brash American nostrums. Many of the late 19th century
+listings continued to follow the procedure set early in the century of
+specifying two grades of the various patent medicines, _i.e._,
+"English" and "American," "genuine" and "imitation," "U.S." and
+"stamped." American manufactories specializing in pharmaceutical
+glassware continued to offer the various English patent medicine
+bottles until the close of the century.[112]
+
+ [109] James Harvey Young, "Patent medicines: the early
+ post-frontier phase," _Journal of the Illinois State Historical
+ Society_, Autumn 1953, vol. 46, pp. 254-264.
+
+ [110] Cody and Johnson Drug Co., _op. cit._ (footnote 97).
+
+ [111] Van Schaack, Stevenson & Reid, _Annual prices current_,
+ Chicago, 1875; Morrison, Plummer & Co., _Price current of drugs,
+ chemicals, oils, glassware, patent medicines, druggists sundries
+ ..._, Chicago, 1880.
+
+ [112] Hagerty Bros. & Co., _Catalogue of Druggists' glassware,
+ sundries, fancy goods, etc._, New York, 1879; Whitall, Tatum &
+ Co., _Annual price list_, Millville, New Jersey, 1898.
+
+[Illustration: Figure 13.--OPODELDOC BOTTLE from the collection of Mrs.
+Leo F. Redden, Kenmore, New York. (_Smithsonian photo 44201-E._)]
+
+In a thesaurus published in 1899, Godfrey's, Bateman's, Turlington's,
+and other of the old English patent remedies were termed "extinct
+patents."[113] The adjective referred to the status of the patent, not
+the condition of the medicines. If less prominent than in the olden
+days, the medicines were still alive. The first edition of the
+_National Formulary_, published in 1888, had cited the old English
+names as synonyms for official preparations in four cases, Dalby's,
+Bateman's, Godfrey's and Turlington's.
+
+ [113] Emil Hiss, _Thesaurus of proprietary preparations and
+ pharmaceutical specialties_, Chicago, 1899, p. 12.
+
+[Illustration: Figure 14.--OPODELDOC BOTTLE as illustrated in the 1879
+Catalog of Hagerty Bros., New York City, New York.]
+
+Thus as the present century opened, the old English patent medicines
+were still being sold. City druggists were dispensing them over their
+counters, and the peddler's wagon carried them to remote rural
+regions.[114] But the medical scene was changing rapidly. Improvements
+in medical science, stemming in part from the establishment of the germ
+theory of disease, were providing a better yardstick against which to
+measure the therapeutic efficiency of proprietary remedies. Medical
+ethics were likewise advancing, and the occasional critic among the
+ranks of physicians was being joined by scores of his fellow
+practitioners in lambasting the brazen effrontery of the hundreds of
+American cure-alls which advertised from newspaper and roadside sign.
+Journalists joined doctors in condemning nostrums. Samuel Hopkins Adams
+in particular, writing "The Great American Fraud" series for _Collier's
+Weekly_, frightened and aroused the American public with his exposure
+of cheap whiskey posing as consumption cures and soothing syrups filled
+with opium. Then came a revolution in public policy. After a long and
+frustrating legislative prelude, Congress in June of 1906 passed, and
+President Theodore Roosevelt signed, the first Pure Food and Drugs Act.
+The law contained clauses aimed at curtailing the worst features of the
+patent medicine evil.
+
+ [114] Robert B. Nixon, Jr., _Corner druggist_, New York, 1941,
+ p. 68.
+
+
+The Patent Medicines In The 20th Century
+
+Although the old English patent medicines had not been the target at
+which disturbed physicians and "muck-raking" journalists had taken aim,
+these ancient remedies were governed by provisions of the new law. In
+November 1906 the Bureau of Chemistry of the Department of Agriculture,
+in charge of administering the new federal statute, received a letter
+from a wholesale druggist in Evansville, Indiana. One of his stocks in
+trade, the druggist wrote, was a remedy called Godfrey's Cordial. He
+realized that the Pure Food and Drugs Act had something to do with the
+labeling of medicines containing opium, as Godfrey's did, and he wanted
+to know from the Bureau just what was required of him.[115] Many
+manufacturing druggists and producers of medicine were equally anxious
+to learn how the law would affect them. The editors of a trade paper,
+the _American Druggist and Pharmaceutical Record_, issued warnings and
+gave advice. It was still the custom, they noted, to wrap bottles of
+ancient patent medicines, like Godfrey's Cordial and Turlington's
+Balsam, in facsimiles of the original circulars, on which were printed
+extravagant claims and fabulous certificates of cures that dated back
+some two hundred years. The new law was not going to permit the
+continuation of such 18th-century practices. Statements on the label
+"false or misleading in any particular" were banned.[116]
+
+ [115] Letter from Charles Leich & Co. to Harvey Washington Wiley,
+ Bureau of Chemistry, Department of Agriculture, November 2, 1906.
+ Manuscript original in Record Group 97, National Archives,
+ Washington, D.C.
+
+ [116] _American Druggist and Pharmaceutical Record_, 1906, vol.
+ 49, pp. 343-344.
+
+A few manufacturers, as the years went by, fell afoul of this and other
+provisions of the law. In 1918 a Reading, Pennsylvania, firm entered a
+plea of guilty and received a fifty dollar fine for putting on the
+market an adulterated and misbranded version of Dr. Bateman's Pectoral
+Drops.[117] The law required that all medicines sold under a name
+recognized in the _United States pharmacopoeia_ or the _National
+formulary_, and Bateman's was included in the latter, must not differ
+from the standard of strength, quality, or purity as established by
+these volumes. Yet the Bateman Drops produced in Reading, the
+government charged, fell short. They contained only 27.8 percent of the
+alcohol and less than a tenth of the morphine that they should have
+had. While short on active ingredients, the Drops were long on claims.
+The wrapper boasted that the medicine was "effective as a remedy for
+all fluxes, spitting of blood, agues, measles, colds, coughs, and to
+put off the most violent fever; as a treatment, remedy, and cure for
+stone and gravel in the kidneys, bladder, and urethra, shortness of
+breath, straightness of the breast; and to rekindle the most natural
+heat in the bodies by which they restore the languishing to perfect
+health." Okell and Dicey had scarcely promised more. By 20th-century
+standards, the government asserted, these claims were false and
+fraudulent.
+
+ [117] Department of Agriculture, Bureau of Chemistry, Notices of
+ Judgment under the Food and Drugs Act, Notice of Judgment 6222,
+ United States vs. Pabst Pure Extract Co., 1919.
+
+Other manufacturers sold Bateman's Drops without running afoul of the
+law. In 1925, ninety-nine years after the Philadelphia College of
+Pharmacy pamphlet was printed, one North Carolina firm was persuaded
+that it still was relevant to tell potential customers, in a handbill,
+that its Drops were being made in strict conformity with the College
+formula.[118] For Compound Tincture of Opium and Gambir Compound,
+however, most manufacturers chose to follow the _National formulary_
+specifications, which remained official until 1936.
+
+ [118] Original handbill, distributed by Standard Drug Co.,
+ Elizabeth City, North Carolina, 1925, preserved in the files of
+ the Bureau of Investigation, American Medical Association,
+ Chicago, Ill.
+
+Another old English patent medicine against which the Department of
+Agriculture was forced to take action was Hooper's Female Pills.
+Between 1919 and 1923, government agents seized a great many shipments
+of this ancient remedy in versions put out by three Philadelphia
+concerns.[119] Some of the packages bore red seals, others green seals,
+and still others black, but the labeling of all claimed them to be "a
+safe and sovereign remedy in female complaints." This theme was
+expanded in considerable detail and there was an 18th-century ring to
+the promise that the pills would work a sure cure "in all
+hypochondriac, hysterick or vapourish disorders." No pill made
+essentially of aloes and ferrous sulphate, said the government experts,
+could do these things. Nor did the manufacturers, in court, seek to say
+otherwise. Whether the seals were green or red, whether the packages
+were seized in Washington or Worcester, the result was the same. No
+party appeared in court to claim the pills, and they were condemned and
+destroyed.
+
+ [119] Multiple seizures were made of products shipped by the
+ Horace B. Taylor Co., Fore & Co., and the American Synthetic Co.
+ The quotations are from Notice of Judgment 8868; see also 8881,
+ 8914, 8936, 8956, 8974, 9134, 9147, 9203, 9510, 9586, 9785,
+ 10203, 10204, 10629, 11519, 11669.
+
+In one of the last actions under the 1906 law, a case concluded in
+1940, after the first federal statute had been superseded by a more
+rigorous one enacted in 1938, two of the old English patent medicines
+encountered trouble.[120] They were British Oil and Dalby's
+Carminative, as prepared by the South Carolina branch of a large
+pharmaceutical manufacturing concern.
+
+ [120] Federal Security Agency, Food and Drug Administration,
+ Notice of Judgment 31134, United States vs. McKesson and Robbins,
+ Inc., Murray Division, 1942.
+
+According to the label, the British Oil was made in conformity with the
+Philadelphia College of Pharmacy formula given in an outdated edition
+of the _United States dispensatory_. But instead of containing a proper
+amount of linseed oil, if indeed it contained any, the medicine was
+made with cottonseed oil, an ingredient not mentioned in the
+Dispensatory. Therefore, the government charged, the Oil was
+adulterated, under that provision of the law requiring a medicine to
+maintain the strength and purity of any standard it professed to
+follow. More than that, the labeling contravened the law since it
+represented the remedy as an effective treatment for various swellings,
+inflammations, fresh wounds, earaches, shortnesses of breath, and
+ulcers.
+
+Dalby's Carminative was merely misbranded, but that was bad enough. Its
+label suggested that it be used especially "For Infants Afflicted With
+Wind, Watery Gripes, Fluxes and Other Disorders of the Stomach and
+Bowels," although it would aid adults as well. The impression that this
+remedy was capable of curing such afflictions, the government charged,
+was false and fraudulent. Moreover, since the Carminative contained
+opium, it was not a safe medicine when given according to the dosage
+directions in a circular accompanying the bottle. For these and several
+other violations of the law, the defending company, which did not
+contest the case, was fined a hundred dollars.
+
+Throughout the 19th century, occasional criticism of the old English
+patent medicines had been made in the lay press. One novel[121]
+describes a physician who comments on the use of Dalby's Carminative
+for babies: "Don't, for pity's sake, vitiate and torment your poor
+little angel's stomach, so new to the atrocities of this world, with
+drugs. These mixers of baby medicines ought to be fed nothing but their
+own nostrums. That would put a stop to their inventions of the
+adversary."
+
+ [121] John William De Forest, _Miss Ravenel's conversion from
+ secession to loyalty_, New York, 1867.
+
+Opium had been lauded in the 17th and 18th centuries, when the old
+English proprietaries began, as a superior cordial which could moderate
+most illnesses and even cure some. "Medicine would be a one-armed man
+if it did not possess this remedy." So had stated the noted English
+physician, Thomas Sydenham.[122] But the 20th century had grown to fear
+this powerful narcotic, especially in remedies for children. This point
+of view, illustrated in the governmental action concerning Dalby's
+Carminative, was also reflected in medical comment about Godfrey's
+Cordial. During 1912, a Missouri physician described the death of a
+baby who had been given this medicine for a week.[123] The symptoms
+were those of opium poisoning. Deploring the naming of this "dangerous
+mixture" a "cordial," since the average person thought of a cordial as
+beneficial, the doctor hoped that the formula might be omitted from the
+next edition of the _National formulary_. This did not happen, for the
+recipe hung on until 1926. The Harrison Narcotic Act, enacted in 1914
+as a Federal measure to restrict the distribution of narcotics,[124]
+failed to restrict the sale of many opium-bearing compounds like
+Godfrey's Cordial. In 1931, a Tennessee resident complained to the
+medical journal _Hygeia_ that this medication was "sold in general
+stores and drug stores here without prescription and is given to
+babies." To this, the journal replied that the situation was "little
+short of criminal."[125] The charge leveled against his competitors by
+one of the first producers of Godfrey's Cordial two centuries earlier
+(see page 158) may well have proved a prophecy broad enough to cover
+the whole history of this potent nostrum. "... Many Men, Women, and
+especially Infants," he said, "may fall as Victims, whose Slain may
+exceed Herod's Cruelty...."
+
+ [122] Charles H. LaWall, _The curious lore of drugs and medicines
+ (Four thousand years of pharmacy)_, Garden City, New York, 1927,
+ p. 281.
+
+ [123] W. B. Sissons, "Poisoning from Godfrey's Cordial," _Journal
+ of the American Medical Association_, March 2, 1912, vol. 58, p.
+ 650.
+
+ [124] Edward Kremers and George Urdang, _History of pharmacy_,
+ Philadelphia, 1951, pp. 170, 278.
+
+ [125] "Godfrey's Cordial," _Hygeia_, October 1931, vol. 9, p.
+ 1050.
+
+[Illustration: Figure 15.--TURLINGTON'S BALSAM OF LIFE bottles as
+pictured in a brochure dated 1755-1757, preserved in the Pennsylvania
+Historical Society, Philadelphia, Pa. According to Turlington, the
+bottle was adopted in 1754 "to prevent the villainy of some persons
+who, buying up my empty bottles, have basely and wickedly put therein a
+vile spurious counterfeit sort."]
+
+For those who persist in using the formulas of the early English patent
+medicines, recipes are still available. Turlington's Balsam remains
+as an unofficial synonym of U.S.P. Compound Tincture of Benzoin.
+Concerning its efficacy, the _United States dispensatory_[126] states:
+"The tincture is occasionally employed internally as a stimulating
+expectorant in chronic bronchitis. More frequently it is used as an
+inhalent ... It has also been recommended in chronic dysentery ... but
+is of doubtful utility."
+
+ [126] _The dispensatory of the United States of America_, 25th
+ ed., Philadelphia, 1955, p. 158.
+
+A formula for Godfrey's Cordial, under the title of Mixture of Opium
+and Sassafras, is still carried in the _Pharmaceutical recipe
+book_.[127] _Remington's practice of pharmacy_[128] retains a formula
+for Dalby's Carminative under the former _National formulary_ title of
+Carminative Mixture.
+
+ [127] _The Pharmaceutical recipe book_, 2nd ed., American
+ Pharmaceutical Association, 1936, p. 121.
+
+ [128] Eric W. Martin and E. Fullerton Cook, editors, _Remington's
+ practice of pharmacy_, 11th ed., Easton, Pennsylvania, 1956, p.
+ 286.
+
+In the nation of their origin, the continuing interest in the ancient
+proprietaries seems somewhat more lively than in America. The 1953
+edition of _Pharmaceutical formulas_, published by the London journal
+_The Chemist and Druggist_, includes formulas for eight of the ten old
+patent medicines described in this study. This compendium, indeed,
+lists not one, but three different recipes for British Oil, and the
+formulas by which Dalby's Carminative may be compounded run on to a
+total of eight. Two lineal descendents of 18th-century firms which took
+the lead in exporting to America still manufacture remedies made so
+long ago by their predecessors. May, Roberts & Co., Ltd., of London,
+successors to the Newbery interests, continues to market Hooper's
+Female Pills, whereas W. Sutton & Co. (Druggists' Sundries), London,
+Ltd., of Enfield, in Middlesex, successors to Dicey & Co. at Bow
+Churchyard, currently sells Bateman's Pectoral Drops.[129]
+
+ [129] Letter from Owen H. Waller, editor of _The Chemist and
+ Druggist_, to George Griffenhagen, January 15, 1957.
+
+In America, however, the impact of the old English patent medicines has
+been largely absorbed and forgotten. During the past twenty years a
+revolution in medical therapy has taken place. Most of the drugs in use
+today were unknown a quarter of a century ago. Some of the newer drugs
+can really perform certain of the healing miracles claimed by their
+pretentious proprietors for the old English patent medicines.
+
+A more recent import from Britain, penicillin, may prove to have an
+even longer life on these shores than did Turlington's Balsam or
+Bateman's Drops. Still, two hundred years is a long time. Despite the
+fact that these early English patent medicines are nearly forgotten by
+the public today, their American career is none the less worth tracing.
+It reflects aspects not only of medical and pharmaceutical history, but
+of colonial dependence, cultural nationalism, industrial development,
+and popular psychology. It reveals how desperate man has been when
+faced with the terrors of disease, how he has purchased the packaged
+promises offered by the sincere but deluded as well as by the
+charlatan. It shows how science and law have combined to offer man some
+safeguards against deception in his pursuit of health.
+
+The time seems ripe to write the epitaph of the old English patent
+medicines in America. That they are now a chapter of history is a token
+of medical progress for mankind.
+
+[Illustration: Figure 16.--TURLINGTON'S BALSAM OF LIFE BOTTLE (all four
+sides) found in an Indian grave at Mobridge, South Dakota; now
+preserved in the U.S. National Museum. (_Cat. No. 32462, Archeol.;
+Smithsonian photo 42936-A._)]
+
+
+
+
+
+
+End of the Project Gutenberg EBook of Old English Patent Medicines in America, by
+George B. Griffenhagen and James Harvey Young
+
+*** END OF THIS PROJECT GUTENBERG EBOOK OLD ENGLISH PATENT MEDICINES ***
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