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-The Project Gutenberg eBook of A Statement of Facts Tending to
-Establish an Estimate of the True Value and Present State of
-Vaccination, by Gilbert Blaine
-
-This eBook is for the use of anyone anywhere in the United States and
-most other parts of the world at no cost and with almost no restrictions
-whatsoever. You may copy it, give it away or re-use it under the terms
-of the Project Gutenberg License included with this eBook or online at
-www.gutenberg.org. If you are not located in the United States, you
-will have to check the laws of the country where you are located before
-using this eBook.
-
-Title: A Statement of Facts Tending to Establish an Estimate of the True
- Value and Present State of Vaccination
-
-Author: Gilbert Blaine
-
-Release Date: April 13, 2022 [eBook #67824]
-
-Language: English
-
-Produced by: Charlene Taylor, Daniel Lowe and the Online Distributed
- Proofreading Team at https://www.pgdp.net (This file was
- produced from images generously made available by The
- Internet Archive/American Libraries.)
-
-*** START OF THE PROJECT GUTENBERG EBOOK A STATEMENT OF FACTS TENDING
-TO ESTABLISH AN ESTIMATE OF THE TRUE VALUE AND PRESENT STATE OF
-VACCINATION ***
-
-
- A
-
- STATEMENT OF FACTS,
-
- TENDING TO
-
- ESTABLISH AN ESTIMATE OF THE TRUE VALUE
-
- AND
-
- PRESENT STATE
-
- OF
-
- VACCINATION.
-
- ----------
-
- BY SIR GILBERT BLANE, BART.
-
- _F.R.S. of London, Edinburgh, and Göttingen; Member of the Imperial
- Academy of St. Petersburgh; and Physician in Ordinary to the King._
-
- -------------------------
-
- FROM THE TENTH VOLUME OF THE MEDICO-CHIRURGICAL TRANSACTIONS, PUBLISHED
- BY THE MEDICAL AND CHIRURGICAL SOCIETY OF LONDON;
-
- WITH ADDITIONS.
-
- -------------------------
-
- LONDON:
-
- PRINTED FOR THOMAS AND GEORGE UNDERWOOD, 32, FLEET STREET.
-
- ----------
-
- 1820.
-
-------------------------------------------------------------------------
-
- J. MOYES, GREVILLE STREET, LONDON.
-
-------------------------------------------------------------------------
-
- A
-
- STATEMENT OF FACTS,
-
- TENDING TO ESTABLISH AN ESTIMATE OF THE TRUE VALUE AND
- PRESENT STATE OF
-
- VACCINATION.
-
- BY SIR GILBERT BLANE, BART. F.R.S. Lond. &c.
-
- _Physician in Ordinary to the King._
-
- -------------------------
-
- _Read Nov. 10, 1819._
-
- -------------------------
-
-It is now twenty-one years since Vaccination was promulgated in this
-country by Dr. Jenner, and fifteen years since it began to produce a
-sensible effect in diminishing the mortality from Small Pox. In regard
-to the latter period, it is coeval with this Society; yet, though no
-discovery in nature nor in medicine has been more important to the
-interests of humanity, nor any which has ever so rapidly and universally
-won the assent and practical adoption of mankind, there are no notices
-of it on our records, except in our second volume, in an article by Dr.
-Bateman, in which he relates a case of a mother who was affected with
-the Small Pox a second time, by being exposed to infection, from some of
-her own children who had caught it casually; while her other children,
-who had been vaccinated, resisted it. As it is to be hoped that our
-labours will prove to posterity some of the principal sources of
-reference regarding the medical and chirurgical discoveries and
-improvements of the age; as it is one of the reproaches of our country,
-that it has not availed itself so much as any other of the benefits of
-Vaccination; and as there are writers among us who still allege that the
-failures are so numerous that the value of the discovery is very
-ambiguous, it seems one of the duties of the Society to lend its aid in
-placing these important points in their true light.
-
-It seems almost needless to premise, that the Small Pox is of all
-maladies that, which, during the last thousand years, has destroyed the
-largest portion of the human species, and been productive of the largest
-share of human misery. There is, perhaps, no disease over which medical
-art has less power; and this power, such as it is, has consisted more in
-abolishing pernicious practices, than in ascertaining any positive
-methods of controlling its fatality, unless we except the inoculation of
-it with its own _virus_. But, though the beneficial effect of this on
-those on whom it is actually practised is undeniable, it has no tendency
-like Vaccination to extirpate the disease; and from the impossibility of
-rendering it universal, it has actually been found to add to the general
-mortality of Small Pox, by opening a new source for the diffusion of its
-_virus_.
-
-It ought to be stated also, with a view to a decision on this question,
-that Vaccination itself is attended with no danger, and frequently takes
-effect without any visible disturbance in the system. There is even
-reason to believe, that in its process it wards off other diseases, by
-pre-occupying the constitution.
-
-In order to bring this matter to the test of calculation, in order also
-to institute a comparison of the mortality of Small Pox as influenced by
-Vaccination, as well as by Inoculation from itself, I have selected from
-the bills of mortality four periods, each of fifteen years, for the
-purpose of exhibiting the mortality of Small Pox in each of these series
-in regard to each other. These are thrown into the form of Tables, and
-annexed to this article.
-
-The first series, is the fifteen years immediately preceding the
-introduction of Inoculation; that is, from 1706 to 1720, both included.
-Previous to this period, no account that could be depended upon
-regarding the Small Pox, could be derived from the bills of mortality;
-for down to the beginning of last century such was their imperfect
-construction, that Small Pox, Measles, and Flux were blended under one
-head. Exception may be taken against the accuracy of these bills, even
-in this improved state, particularly with regard to the discrimination
-of diseases. This objection, however, is certainly less applicable to
-Small Pox than any other disorder, its character being so striking as
-not to be mistaken by the most ignorant and careless observer.
-
-The second series is taken at the middle of the last century, when
-Inoculation had made considerable progress; that is, from 1745 to 1759,
-both included. In comparing this with the preceding series, with regard
-to absolute numbers, it ought to be taken into account, that eleven
-parishes were added to the bills of mortality, between the years 1726
-and 1745, both included: so that the progressive improvement of general
-salubrity ought to be estimated still higher than what is indicated by
-the diminished mortality, as it stands in the Tables.
-
-The third series comprises the fifteen years previous to the
-introduction of Vaccination, when Inoculation had made still greater
-progress; that is, from 1785 to 1798, both included.
-
-The fourth series comprises the time in which the vaccine Inoculation
-has been so far diffused as to produce a notable effect on the mortality
-of Small Pox; that is, from 1804 to 1818, both included.
-
-The result of these computations stands as follows:—
-
- _Ratio of the Mortality of Small Pox to the total Mortality._
-
- From 1706 to 1720, one in 12.7; that is, 78 in 1000.
- From 1745 to 1759, one in 11.2; that is, 89 in 1000.
- From 1785 to 1798, one in 10.6; that is, 94 in 1000.
- From 1804 to 1818, one in 18.9; that is, 53 in 1000.
-
- Fractions are not noticed in the last column of numbers.
-
-It appears from this statement, that the proportion of deaths from Small
-Pox to the total mortality, increased in the course of last century; so
-that Inoculation appears to have added to the mortality. It is but fair
-to mention, however, that this total mortality is not quite a just scale
-whereby to measure the relative mortality of Small Pox; for in the
-course of that century, the general mortality itself was greatly
-diminished in relation to the population. This diminution of general
-mortality was chiefly owing to the diminished mortality of children
-under two years of age, which, at the time when the account began to be
-kept, 1729, averaged about 9000; but at the end of the century not more
-than 5000[1]; also to the decrease of fevers, and still more of fluxes.
-The relation of the mortality of Small Pox to the population, would
-therefore be a more fair criterion of its increase or decrease. In this
-view it might, at first sight, be thought that it had decreased; for the
-population of the metropolis nearly doubled in the course of the last
-century. But it is to be remarked, that there has been little increase
-of population in that portion of the metropolis which is included in the
-bills of mortality; the great increase having been in the parishes of
-Mary-le-bone and St. Pancras, which are not included in these bills. It
-is computed in the remarks subjoined to the last parliamentary returns
-of population, that the population of London, within the walls, had
-decreased more than three-fifths in the course of last century, from the
-widening of streets, the erection of public buildings and warehouses,
-and, it might have been added, from the migration of mercantile families
-to the west end of the town. As a set-off to this, there has certainly
-been a great addition, in the same time, to those parishes within the
-bills, which stand on the verge of the metropolis, such as St. George’s
-Hanover Square, St. George’s Bloomsbury, Poplar, and Stepney. But the
-addition to the population, if any, within the bills of mortality, does
-not seem to be so considerable as to affect the computation. And, if
-this is admitted, the absolute numbers of the deaths from Small Pox,
-estimated in relation to the population, that is, exactly as they stand
-on the Tables, afford a fair comparative statement of the mortality in
-the last century, and seem to prove that Inoculation has not added so
-much to it as has been alleged. It was in the rural population that the
-effect of Inoculation in diffusing Small Pox was chiefly felt. In this
-situation there is much less intercourse of persons with each other than
-in towns, so that not only many individuals escaped from their not being
-exposed to infection during their whole lives, but whole districts were
-known to have been exempt from it for a long series of years, before it
-was universally diffused by Inoculation.
-
-But the truly important result from these statements consists in the
-clear, undeniable, and great diminution of it since the introduction of
-Vaccination. It appears, that in the last fifteen years, the mortality
-from Small Pox, in the bills of mortality, has not been much more than
-one-half of what it was in the two like series of years in the middle
-and latter end of the last century. Nor does this comprise the whole
-benefit derived from this discovery in the metropolis; for, besides that
-the sixth part of it lies without the bills, it was found, in levying
-the tax on burials for the last six months of 1794, that the number of
-unregistered deaths, chiefly those of dissenters, amounted in that half
-year to 3148; and the reporter of the parliamentary enumeration thinks
-that, as besides these there were undiscovered interments, the
-unregistered deaths may be computed at one-third of the total mortality,
-that is, about 7000. (_See Abstract of the Parish Registers, 1811,
-printed by authority of Parliament, page 200._)
-
-Assuming, therefore, that Vaccination had not been practised the last
-fifteen years, and that the mortality from Small Pox, within the bills,
-had in that time, that is, from 1804 to 1818, been the same as from 1784
-to 1798, that is, 27,569 in place of 14,716; and assuming that there has
-been the same proportional diminution of deaths in the districts without
-the bills, and among the unregistered subjects, the account of lives
-saved in this metropolis by Vaccination in the fifteen years, will stand
-as follows:—
-
- Within the bills of mortality 12,853
- Without the bills of mortality 2,570
- Unregistered cases 7,711
- ------
- Total 23,134
-
-The first of these numbers is found by subtracting the amount of deaths
-by Small Pox, in the bills of mortality, during the practice of
-Vaccination, from the amount of them, during the same number of years,
-immediately before the discovery of Vaccination.
-
-The second number is found by dividing the first by 5. The population of
-the metropolis without the bills is stated at one-sixth of the whole,
-which is evidently one-fifth of that within the bills.
-
-The third number is found by dividing the sum of the two others by 2;
-the unregistered cases being, as before stated, one-third of the whole.
-
-It appears, therefore, that, even under the very imperfect practice of
-Vaccination which has taken place in this metropolis, 23,134 lives have
-been saved in the last fifteen years, according to the best computation
-that the _data_ afford. It will be seen, by an inspection of the Table,
-that in that time there have been great fluctuations in the number of
-deaths. This has been owing partly to the Small Pox Inoculation of
-out-patients having, by an unaccountable infatuation, been kept up at
-the Small Pox Hospital for several years after the virtue of Vaccination
-had been fully confirmed. The greater number of deaths in 1805 may
-chiefly be referred to this cause. Since the suppression of this
-practice, the adoption of Vaccination, though in a degree so incomplete,
-in consequence of public prejudice, created entirely by mischievous
-publications, has been unable to prevent a considerable, though
-fluctuating, mortality from Small Pox. The late mortality from Small
-Pox, though little more than one half of what it was in former times,
-might have been entirely saved, if Vaccination had been carried to the
-same extent as in many cities and whole districts on the continent of
-Europe, in Peru, and Ceylon.
-
-In the summer of 1811 the author was called to visit, professionally,
-Don Francisco de Salazar, who had arrived a few days before in London,
-on his route from Lima to Cadiz, as a deputy to the Spanish Cortes. He
-informed him, that Vaccination had been practised with so much energy
-and success in Lima, that for the last twelve months there had occurred,
-not only no death from, but no case of, Small Pox; that the new-born
-children of all ranks are carried as regularly to the Vaccinating House
-as to the font of baptism; that the Small Pox is entirely extinguished
-all over Peru; nearly so in Chili; and that there has been no compulsory
-interference on the part of the government to promote Vaccination.
-
-It is now matter of irrefragable historical evidence, that Vaccination
-possesses powers adequate to the great end proposed by its meritorious
-discoverer, in his first promulgation of it in 1798, namely, the total
-extirpation of Small Pox. The first proof of this was at Vienna, where,
-in 1804, no cases occurred, except two strangers who came into the city
-with the disease upon them. In 1805 there did not occur a single death
-from it in Copenhagen[2]. Dr. Sacco, the indefatigable superintendent of
-Vaccination in Lombardy, stated, in his Annual Report, 3d January, 1808,
-that the Small Pox had entirely disappeared in all the large towns in
-that country; and that in the great city of Milan it had not appeared
-for several years. Dr. Odier, of Geneva, so favourably known for his
-high professional, scientific, and literary acquirements, testifies,
-that, after a vigorous perseverance in Vaccination for six years, the
-Small Pox had disappeared in that city and the whole surrounding
-district; and that, when casually introduced by strangers, it did not
-spread, the inhabitants not being _susceptible_. The Central Committee
-in Paris testify, in their Report of 1809, that the Small Pox had been
-extinguished at Lyons and other districts of France.
-
-These are selected as some of the earliest and most remarkable proofs of
-the extirpating power. But it is demonstrable, that if at the first
-moment of this singular discovery, at any moment since, at the present
-or any future moment, mankind were sufficiently wise and decided to
-vaccinate the whole of the human species who have not gone through the
-Small Pox, from that moment would this most loathsome and afflicting of
-all the scourges of humanity be instantaneously, and for ever, banished
-from the earth.
-
-It is farther manifest, that extirpation being the ultimate aim of this
-discovery, and there being the fullest historical and practical evidence
-of its being capable of accomplishing this end, all other questions with
-regard to its expediency must be futile and irrelevant. It is in the
-nature of all morbid phenomena to be liable to exception. One of the
-most essential and characteristic laws of Small Pox itself, namely, that
-of its affecting the human subject but once in life, is found in rare
-cases to be violated. It is, therefore, perfectly conformable to
-analogy, and naturally to be expected, that it may not in all cases be a
-complete security against Small Pox. But it is obvious, that, admitting
-these exceptions to be very frequent, much more so than the recurrence
-of Small Pox after Small Pox, this can constitute no objection to the
-practice, as long as the extirpating power remains unimpaired and
-unimpeached. Nay, it is obviously so far from an objection, that it
-ought to operate as a powerful additional incentive on every benevolent
-mind, to push Vaccination to the utmost, as rapidly as possible, in
-order that those who are still susceptible, either from peculiar natural
-constitution, or from the unskillful manner of conducting the operation,
-or from defective matter, may not, by any possibility, catch it; for, in
-the event of its extirpation, it could nowhere be met with. And in order
-to stimulate the good and the wise to aim strenuously at this
-consummation, let it be constantly borne in mind, that the adversary
-they are contending with is the greatest scourge that has ever afflicted
-humanity. That it is so, all history, civil and medical, proclaims: for,
-though the term Plague carries a sound of greater horror and dismay, we
-should probably be within the truth, if we were to assert, that Small
-Pox has destroyed a hundred for every one that has perished by the
-Plague.
-
-It is true that in its last visitation of this metropolis, one hundred
-and fifty-four years ago, it carried off 70,000 victims in a few months;
-but since that time, the deaths from Small Pox, recorded in the bills of
-mortality, have amounted to more than 300,000; and a like number of the
-survivors have been afflicted with blindness, deformity, scrofula, or
-broken constitutions, which is not the case with the survivors of the
-Plague. It appears, by a Report of the Hospital for the Indigent Blind,
-that two thirds of those who apply for relief have lost their sight by
-the Small Pox. It is alleged by some of the soundest Political
-Economists that Small Pox does not diminish the numbers of mankind, nor
-Vaccination increase them; for population is determined by subsistence,
-and the indefinite powers of procreation soon repair the ravages of
-disease. But, however true this may be, the miseries incident to so many
-of those who survive Small Pox, whereby they become a burden to
-themselves, their families, and to society, render this disease
-uncontrovertibly an evil of the first magnitude, not to mention the
-intense sufferings and afflictions inseparable from it; and in this view
-of the matter the objection seriously adduced against Vaccination by one
-of its opponents[3], that _Small Pox is a merciful dispensation of
-Providence for the poor man, by diminishing the burden of his family_,
-will not hold good, for the burden is not removed.
-
-And when it is considered that there are large portions of the globe,
-India, China, even one whole quarter of it (North and South America),
-besides all the tropical and arctic regions, in which the Plague has
-never been known; and that in all the countries liable to it, it seldom
-appears but at one season of the year, and in some at long intervals,
-the ravage which it makes is trifling when compared with the unceasing
-havoc of Small Pox, which spares no nation in any climate, or at any
-season. Yet the Legislative Regulations for excluding and checking the
-Plague are of the most harsh and despotic description, while the law
-touches upon Small Pox comparatively with the most lenient hand. It
-ought to be generally known, however, that in a late trial and
-conviction, it was laid down by the judge to be the law of the land,
-that a medical practitioner who neglects to exclude the person whom he
-inoculates from communication with others, is liable to fine and
-imprisonment. Morally considered, indeed, it is difficult to conceive a
-higher degree of flagitious turpitude than that of a professional
-person, in the present state of knowledge, exposing his
-fellow-creatures, from sordid motives, to one of the most grievous
-calamities of which human nature is susceptible.
-
-The preceding reasoning is grounded on the supposition of extirpation:
-but, however demonstrable the _possibility_ of extirpation may be, it
-may not in all communities be _practicable_; and may not these alleged
-failures so operate, as, in such circumstances, to render the expediency
-of the practice questionable?
-
-In order to decide this, let the nature and amount of these failures be
-ascertained and estimated.
-
-The description of those cases of Small Pox, (if they can be called so,)
-which occur in vaccinated subjects, is shortly as follows:—The invasion
-and eruption in every respect resembles that of the genuine Small Pox. I
-have seen it attended with high fever and a thick crowded crop of
-_papulæ_, such as precedes the most severe and dangerous cases of the
-confluent kind. This runs on till the fifth day from the eruption, both
-days included, at which time some of the _papulæ_ begin to be converted
-into small sized pustules. The disorder then abruptly stops short. On
-the following day the fever is found to have subsided, with a
-shrivelling and desiccation of the eruption, and recovery proceeds
-without the least danger or inconvenience. The face is marked, for some
-time after, with brown spots, but without pits. It should never be
-forgotten, that all morbid _phænomena_ are full of varieties and
-exceptions. Accordingly, though the fifth day is the most common limit
-of this disorder, it sometimes stops short on the third; sometimes not
-till the sixth or seventh; and, in a very few cases, it has been known
-to run the common course of Small Pox. What forms the strong line of
-distinction from proper Small Pox, is that, with a few exceptions, it
-does not advance to maturation and secondary fever, which is the only
-period of danger. I am not prepared to deny that death may not have
-occurred in a few instances; nay, there seems sufficient evidence that
-it actually has; but these adverse cases are so rare, as not to form the
-shadow of an objection to the expediency of the general practice. A few
-weeks ago at a meeting of this Society, at which forty members and
-visitors were present, I put the question whether any of these eminent
-and extensive practitioners had met with any fatal cases of this kind.
-Two gentlemen had each seen a single case, and two other gentlemen took
-occasion to say that they had each seen a case of second Small Pox, both
-of which proved fatal. It is evident, therefore, that according to that
-maxim which guides mankind in the conduct of life, namely, that of
-acting on a general rule and average, and not on exceptions, these
-adverse instances ought not to have the least influence on practice,
-even though they were much more numerous. Nor indeed do they, except in
-the very rare cases here cited, deserve the name of failures; for,
-though they fail in preventing _Small Pox_, they do not fail to prevent
-_Death_. And let me here, in the name of humanity, beseech practitioners
-not to be forward in publishing single cases of failures, real or
-supposed; for, when the weak minded and uninformed hear of these
-failures, without hearing at the same time that there are hundreds of
-cases of permanent security for every single case of failure, they are
-guided by the _exception_, which becomes to them the _rule_; their
-judgments being thereby most fatally perverted.
-
-As it is of the utmost consequence to establish the strong and important
-distinction between Small Pox, properly so called, and that which takes
-place after Vaccination, which may be called the mitigated, or five day
-Small Pox, a few of the most impressive testimonies respecting the safe
-nature of the latter may be here recited. Mr. Brown[4], of Musselburgh,
-gives the detail of forty-eight cases, in none of which did the
-secondary fever nor death occur. Here was a saving of at least eight
-lives, at the lowest computation; for this is the number which, by the
-average mortality of natural Small Pox, would have died if the
-constitutions of these forty-eight persons had not been modified by
-previous Vaccination. Dr. Dewar, of Edinburgh, hearing that many
-vaccinated subjects had been affected with Small Pox at Cupar in Fife,
-where the natural Small Pox at the same time prevailed, he most laudably
-repaired to the spot to investigate the subject. He found that
-fifty-four vaccinated subjects had caught the Small Pox. All these,
-except one, had the mitigated or five day eruptive fever, and livid. The
-fatal case was that of a child, who had a complication of other
-disorders, and having died on the fifth day, the Small Pox, according to
-its ordinary course of fatality, could not of itself be the cause of
-death. All the rest were safe; while of sixteen cases of the natural
-Small Pox at the same time and place, six died; so that, if these
-fifty-three cases had not undergone the mitigating process of
-Vaccination, nineteen or twenty would have perished. Between thirty and
-forty cases of the same kind have occurred at Carlisle, on the testimony
-of Dr. Barnes, a respectable practitioner of that city[5]. Many proofs
-might be adduced from the oral testimony of private practitioners, which
-would overswell this article. The only other to be mentioned is from the
-Report of the Central Committee of Vaccination at Paris, made in
-December last, in which the description of the disease occurring after
-Vaccination corresponds exactly with the mitigated five day cases which
-have occurred in Britain. They refuse the name of Small Pox to it; but
-as I know from my own observation, as well as from the testimony of
-others, that the matter from it does by Inoculation give the Small Pox,
-we can hardly, perhaps, with propriety deny it that name; but it should
-be distinguished by some strong discriminating epithet, such as is
-suggested above.
-
-As the attack of Small Pox in subjects who have undergone Vaccination,
-generally occurs after a long interval, it becomes a question whether
-this is owing merely to the chance of such subjects not having been
-exposed to variolous contagion, or to the effect of time in diminishing
-the antivariolous virtue of vaccination. The former is certainly
-conceivable; but when we consider the numberless severe proofs to which
-the recently vaccinated were experimentally exposed in the early part of
-this practice all over Europe, from which the most satisfactory evidence
-resulted; and when it is considered that, in the great majority of
-cases, Small Pox has not occurred till several years after vaccination,
-it seems by far most probable that the virtue of it is weakened by time.
-When parents, therefore, become anxious and apprehensive regarding the
-risk of Small Pox after a lapse of years, it seems quite reasonable that
-they should be indulged in having the operation repeated.
-
-Let all this be applied to the case of a community, in which the total
-eradication of Small Pox is quite hopeless. Let it be admitted that such
-occurrences as have been described do frequently occur: let it even be
-admitted, for argument’s sake, that every vaccinated case whatever must
-of necessity and unavoidably at some time or other in future life be
-affected with this mitigated species of Small Pox, would it not even
-under this great abatement be one of the greatest boons that could be
-conferred on humanity, being an instrument or remedy which would disarm
-Small Pox of its danger? Would not the next greatest benefit to the
-total extirpation of Small Pox, be the stripping it of its terrors by
-rendering it safe and harmless?
-
-It may be further remarked, that the benefit derivable from the
-different proportions of the persons vaccinated to the total population,
-advances in a considerably higher progression than the simple
-arithmetical. It is evident that the smaller the relative number of the
-vaccinated, the greater their chance of meeting with Small Pox
-infection, and that though the disease which they may catch is of a
-mitigated nature, it would nevertheless be desirable to avoid it on its
-own account, but still more on account of the prejudice it creates.
-This, in the eye of general benevolence, constitutes an additional,
-though secondary motive for extending the vaccine inoculation as widely
-as possible, even though the attainment of the _maximum_, that is, total
-extirpation, should be impracticable and hopeless.
-
-It is of the highest importance to society, that this subject should be
-seen in its true light, and in all its bearings; for the frequent
-occurrence of these cases of Small Pox, however safe in themselves, have
-had a most pernicious effect on the credulous and ignorant, by giving a
-check to the practice of Vaccination. It ought never to be forgot that
-the power of Vaccination in extirpating Small Pox being established, the
-question of its expediency is completely set at rest. How many parents
-are there now who, from a weak distrust in the virtue of Vaccination,
-have to lament the loss of a child from Small Pox, either casual or
-inoculated? Many such are known to myself. It is pleasing, however, to
-observe, that though this unmerited discredit into which Vaccination had
-fallen, swelled the number of deaths in London from Small Pox to 1051 in
-1817, good sense is likely still to prevail, for last year (1818) the
-deaths have fallen lower than they have ever been known since the
-institution of the bills of mortality, the total number being only
-421[6].
-
-On the whole matter, I believe I am speaking the language of every man
-of good principles and feelings, capable of reflecting seriously and
-considerately on the subject, when I say, that whenever he applies his
-mind to it, he finds some new and increasing cause of complacency and
-satisfaction. Viewed as a mere physical fact in the natural history of
-the animal kingdom, the virtue of the vaccine _virus_ in resisting the
-action of the _variolous_, is, by its novelty and singularity, highly
-striking and interesting to every one whose taste leads him to take
-delight in contemplating and exploring the devious ways and varied forms
-of Nature, as curious exceptions to the uniformity and constancy of her
-laws. One can hardly contemplate with sufficient astonishment, the
-extraordinary fact that a morbid poison taken from a domestic animal
-should, when inserted into the human body, shield it against the assault
-of one of the most fatal and cruel maladies to which it is incident. But
-the importance of this, as a physical curiosity, vanishes to nothing
-when the unexampled benefits of it to mankind are fairly weighed;
-benefits which could never have been dreamt of by the most sanguine
-philanthropist, who, in contemplating it, finds himself lost in
-astonishment, at a boon to mankind almost beyond the grasp of his mind
-duly to appreciate: so that what seems at first sight merely a sportive
-aberration from the usual course of things, has, by the wise
-dispensation of Providence, become subservient to the most beneficent
-purposes: and how many more useful discoveries may there yet be in
-reserve for the alleviation of human misery, from obscure and undetected
-facts still lurking under the very surface of Nature! It will in the
-eyes of future ages be deemed an _epocha_ in the destinies of the world,
-and one of the highest boasts of the country in which it took its rise,
-with a sense of unrequitable obligation to the individual[7] who first
-disclosed and promulgated the secret, by drawing it from the dark
-recesses of rural tradition, and rendering it available to the whole
-human race.
-
-Such are the sentiments which must fill every well constituted mind; and
-it behoves the whole medical profession, which has already done itself
-so much honour by the zealous and disinterested encouragement afforded
-to it, to continue its efforts in eradicating every remaining prejudice
-against it. It becomes Englishmen, in particular, to cherish it, not
-only as the native offspring of their country, of which they have reason
-to be proud, but to redeem the character of the nation from the reproach
-of having, of all others, whether savage or civilized, done the least
-justice to this noble discovery. It is somewhat humiliating to reflect,
-that while there is no country which has received more striking and
-unambiguous benefits from this discovery, there is none which has prized
-it less, nor availed itself of it so little. I here allude to the
-unspeakable advantage of it to the public service, both by sea and land,
-in the late war, so eventful and portentous in its course, and so
-glorious in its termination. Formerly, Small Pox was one of the greatest
-embarrassments to the operations of armies; and ships of war were
-occasionally under the necessity of quitting the sea, from the
-prevalence of this disorder among their crews. Those lately at the head
-of the navy and army, with that vigilant wisdom and humanity which
-become those who direct the affairs of a great and enlightened nation,
-recommended and enforced the practice of Vaccination in both these
-departments, to the great furtherance of the public service. Their
-example has by no means been followed among the civil population of
-England. This is chiefly imputable to the abuse of the press, the
-general licentiousness of which may be denounced as one of the most
-grievous evils of this age and country, in regard to other subjects
-interesting to humanity and public happiness, as well as this; the
-votaries of error and depravity being more successful, because they find
-more encouragement in disseminating their principles, than the advocates
-of truth, virtue, and good order. There is no maxim more true, than that
-the best things do become by abuse the worst, and that in proportion to
-their excellence. What a mortifying contrast does England form with
-Peru, where it was adopted instantly, in consequence of a flash of
-conviction from the light of evidence! and was not this conviction fully
-justified by the immediate disappearance of Small Pox from that whole
-region? To those nations who may feel an envy of the glory attached to
-our country by this discovery, it must be no small consolation to
-perceive that a large proportion of the English nation has hitherto been
-so besotted as not to know how to appreciate it, nor how to avail
-themselves of it, and that it has encountered more opposition among
-ourselves than in all the world besides.
-
-------------------------------------------------------------------------
-
- TABLE I.
-
- ┌──────┬──────────┬──────────────┬───────────┬──────────┐
- │Years.│ Total │Mortality from│Proportion.│Proportion│
- │ │Mortality.│ Small Pox. │ │ to 1000. │
- ├──────┼──────────┼──────────────┼───────────┼──────────┤
- │ 1706 │ 22,097 │ 1094 │1 in 20 │ 50│
- │ 1707 │ 21,600 │ 1078 │1 20 │ 50│
- │ 1708 │ 21,291 │ 1687 │1 12-1/2│ 79│
- │ 1709 │ 21,800 │ 1024 │1 21 │ 49│
- │ 1710 │ 24,620 │ 3138 │1 8 │ 127│
- │ 1711 │ 19,833 │ 915 │1 21-1/2│ 46│
- │ 1712 │ 21,198 │ 1943 │1 11 │ 92│
- │ 1713 │ 21,057 │ 1614 │1 13 │ 77│
- │ 1714 │ 26,569 │ 2810 │1 9-1/2 │ 106│
- │ 1715 │ 22,232 │ 1057 │1 21 │ 47│
- │ 1716 │ 24,436 │ 2427 │1 10 │ 100│
- │ 1717 │ 23,446 │ 2211 │1 10-1/2│ 94│
- │ 1718 │ 26,523 │ 1884 │1 14 │ 71│
- │ 1719 │ 28,347 │ 3229 │1 8-3/4 │ 114│
- │ 1720 │ 25,454 │ 1440 │1 17-1/2│ 56│
- ├──────┴──────────┼──────────────┼───────────┼──────────┤
- │ Total—350,503 │ 27,557 │1 12.7 │ 78│
- └─────────────────┴──────────────┴───────────┴──────────┘
-
- In this series it appears that the deaths from Small Pox are, to the
- total mortality, as 1 in 12.7; that is, 78 in 1000.
-
-------------------------------------------------------------------------
-
- TABLE II.
-
- ┌──────┬──────────┬──────────────┬───────────┬──────────┐
- │Years.│ Total │Mortality from│Proportion.│Proportion│
- │ │Mortality.│ Small Pox. │ │ to 1000. │
- ├──────┼──────────┼──────────────┼───────────┼──────────┤
- │ 1745 │ 21,296 │ 1206 │1 in 17-3/4│ 56│
- │ 1746 │ 28,157 │ 3236 │1 8-3/4 │ 115│
- │ 1747 │ 25,494 │ 1380 │1 18-1/2│ 54│
- │ 1748 │ 23,869 │ 1789 │1 13-1/2│ 75│
- │ 1749 │ 25,516 │ 2625 │1 9-3/4 │ 103│
- │ 1750 │ 23,727 │ 1229 │1 19-1/4│ 52│
- │ 1751 │ 21,028 │ 998 │1 21 │ 48│
- │ 1752 │ 20,485 │ 3538 │1 5-3/4 │ 172│
- │ 1753 │ 19,276 │ 774 │1 25 │ 40│
- │ 1754 │ 22,696 │ 2359 │1 9-1/2 │ 104│
- │ 1755 │ 21,917 │ 1988 │1 11 │ 91│
- │ 1756 │ 20,872 │ 1608 │1 13 │ 77│
- │ 1757 │ 21,313 │ 3296 │1 6-1/2 │ 155│
- │ 1758 │ 17,576 │ 1273 │1 13-3/4│ 73│
- │ 1759 │ 19,604 │ 2596 │1 7-1/2 │ 132│
- ├──────┴──────────┼──────────────┼───────────┼──────────┤
- │ Total—332,826 │ 29,895 │1 11.2 │ 89│
- └─────────────────┴──────────────┴───────────┴──────────┘
-
- In this series it appears that the proportion of deaths from Small Pox
- is, to the total mortality, as 1 in 11.2; that is, 89 in 1000.
-
-------------------------------------------------------------------------
-
- TABLE III.
-
- ┌──────┬──────────┬──────────────┬───────────┬──────────┐
- │Years.│ Total │Mortality from│Proportion.│Proportion│
- │ │Mortality.│ Small Pox. │ │ to 1000. │
- ├──────┼──────────┼──────────────┼───────────┼──────────┤
- │ 1784 │ 20,454 │ 1210 │1 in 17 │ 59│
- │ 1785 │ 18,919 │ 1999 │1 9-1/2 │ 106│
- │ 1786 │ 20,445 │ 1210 │1 17 │ 59│
- │ 1787 │ 19,349 │ 2418 │1 8 │ 125│
- │ 1788 │ 19,697 │ 1101 │1 17-3/4│ 56│
- │ 1789 │ 20,749 │ 2077 │1 10 │ 100│
- │ 1790 │ 18,038 │ 1617 │1 11-1/4│ 89│
- │ 1791 │ 18,760 │ 1747 │1 10-3/4│ 93│
- │ 1792 │ 20,313 │ 1568 │1 13 │ 77│
- │ 1793 │ 21,749 │ 2382 │1 9 │ 11│
- │ 1794 │ 19,241 │ 1913 │1 10 │ 99│
- │ 1795 │ 21,179 │ 1040 │1 20-1/4│ 49│
- │ 1796 │ 19,288 │ 3548 │1 54 │ 18│
- │ 1797 │ 17,014 │ 512 │1 33-1/2│ 30│
- │ 1798 │ 18,155 │ 2237 │1 8 │ 123│
- ├──────┴──────────┼──────────────┼───────────┼──────────┤
- │ Total—293,350 │ 26,579 │1 11 │ 90.9│
- └─────────────────┴──────────────┴───────────┴──────────┘
-
- In this series it appears that the proportion of deaths from Small Pox
- to the total mortality is 1 in 11, that is, 90.9 in 1000.
-
-------------------------------------------------------------------------
-
- TABLE IV.
-
- ┌──────┬──────────┬──────────────┬───────────┬──────────┐
- │Years.│ Total │Mortality from│Proportion.│Proportion│
- │ │Mortality.│ Small Pox. │ │ to 1000. │
- ├──────┼──────────┼──────────────┼───────────┼──────────┤
- │ 1804 │ 17,038 │ 622 │1 in 27-1/2│ 36│
- │ 1805 │ 17,565 │ 1685 │1 10-1/2│ 96│
- │ 1806 │ 18,334 │ 1297 │1 14 │ 71│
- │ 1807 │ 17,938 │ 1158 │1 15-1/2│ 65│
- │ 1808 │ 19,964 │ 1169 │1 17-1/4│ 58│
- │ 1809 │ 16,680 │ 1163 │1 14-1/4│ 70│
- │ 1810 │ 19,893 │ 1198 │1 16-1/2│ 60│
- │ 1811 │ 17,043 │ 751 │1 22-3/4│ 44│
- │ 1812 │ 18,295 │ 1287 │1 14-1/4│ 70│
- │ 1813 │ 17,322 │ 898 │1 19-1/4│ 52│
- │ 1814 │ 19,783 │ 638 │1 31 │ 32│
- │ 1815 │ 19,560 │ 725 │1 27 │ 37│
- │ 1816 │ 20,316 │ 653 │1 31-1/4│ 32│
- │ 1817 │ 19,968 │ 1051 │1 19 │ 53│
- │ 1818 │ 19,705 │ 421 │1 47 │ 21│
- ├──────┴──────────┼──────────────┼───────────┼──────────┤
- │ Total—279,404 │ 14,716 │1 18.9 │ 53│
- └─────────────────┴──────────────┴───────────┴──────────┘
-
- In this series it appears that the proportion of deaths from Small Pox
- to the total mortality is 1 in 18.9, that is, 53 in 1000.
-
-------------------------------------------------------------------------
-
- LONDON:
-
- PRINTED BY J. MOYES, GREVILLE STREET.
-
------
-
-Footnote 1:
-
- This diminished mortality of young children is, like that of fevers
- and fluxes, owing chiefly to the improvements in ventilation and
- cleanliness, but greatly also to laying aside the custom of exposing
- them to the open air in winter and early in spring; either from
- inadvertency, or from the false notion of rendering them hardy,
- whereas they thereby catch inflammations of the lungs. Nothing tends
- more to the health, strength, and growth of children, than genial
- warmth. It seems chiefly owing to the great plenty and cheapness of
- fuel, that the race of people in Lancashire are so superior in their
- form and size. In Buckinghamshire, on the contrary, where fuel is
- extremely scanty and dear, the race of people is small and puny,
- insomuch that it is provided by Act of Parliament that men shall be
- admitted into the militia of a smaller stature in this than other
- counties.
-
-Footnote 2:
-
- See Pfaff Neuen Nord v. Archiv. B. I.
-
-Footnote 3:
-
- See Serious Reasons for uniformly opposing Vaccination. By John Birch.
- London, 1807.
-
-Footnote 4:
-
- See Inquiry into the Antivariolous power of Vaccination. Ed. 1809.
- There is an article in the Edinburgh Medical Journal by the same
- gentleman in 1819, in which he mentions that he had heard of several
- deaths having occurred from cases of Small Pox after Vaccination. But,
- admitting this, it is utterly incomprehensible by what process of
- reasoning Mr. Brown could on such premises arrive at the conclusion
- that Vaccination ought to be exploded and abandoned.
-
-Footnote 5:
-
- See also a clear and able exposition of this subject in the Medical
- and Surgical Journal of Edinburgh for July, 1818, by Mr. Dunning, of
- Plymouth.
-
-Footnote 6:
-
- Since the first publication of this Tract, it has appeared that in the
- succeeding year (1819), the deaths from the Small Pox had advanced to
- 712; which ought to add to the perseverance, zeal, and vigilance, of
- the friends of humanity in prosecuting Vaccination.
-
-Footnote 7:
-
- Dr. Edward Jenner.
-
- * * * * *
-
- Transcriber’s Notes
-
-Some inconsistencies in spelling, hyphenation, and punctuation have been
-retained.
-
-This file uses _underscores_ to indicate italic text.
-
-*** END OF THE PROJECT GUTENBERG EBOOK A STATEMENT OF FACTS TENDING TO
-ESTABLISH AN ESTIMATE OF THE TRUE VALUE AND PRESENT STATE OF
-VACCINATION ***
-
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